keyword
https://read.qxmd.com/read/38070492/prevalence-diagnostic-delay-and-economic-burden-of-endometriosis-and-its-impact-on-quality-of-life-results-from-an-eastern-mediterranean-population
#21
JOURNAL ARTICLE
Bethan Swift, Bahar Taneri, Christian M Becker, Hasan Basarir, Huseyin Naci, Stacey A Missmer, Krina T Zondervan, Nilufer Rahmioglu
BACKGROUND: There are limited data on endometriosis from the Eastern Mediterranean region. This study for the first time estimates the prevalence and impact of endometriosis on women in Northern Cyprus, an under-represented region in Europe. METHODS: Cyprus Women's Health Research Initiative, a cross-sectional study recruited 7646 women aged 18-55 in Northern Cyprus between January 2018 and February 2020. Cases were identified using self-reported and ultrasound data and two control groups were defined, with (n = 2922) and without (n = 4314) pain...
December 9, 2023: European Journal of Public Health
https://read.qxmd.com/read/38055072/risk-factors-for-major-complications-following-colorectal-resections-for-endometriosis-in-the-usa
#22
JOURNAL ARTICLE
Raanan Meyer, Yosef Y Nasseri, Moshe Barnajian, Matthew T Siedhoff, Kelly N Wright, Kacey M Hamilton, Gabriel Levin, Mireille D Truong
PURPOSE: We aimed to describe the incidence and identify risk factors for the occurrence of short-term major posto-perative complications following colorectal resection for endometriosis. METHODS: A cohort study using data from the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database from 2012-2020. We included patients with a primary diagnosis of endometriosis who underwent colon or rectal resections for endometriosis. RESULTS: Of 755 women who underwent colorectal resection, 495 (65...
December 6, 2023: International Journal of Colorectal Disease
https://read.qxmd.com/read/38043860/robotic-management-of-recurrent-rectal-endometriosis-after-previous-segmental-bowel-resection
#23
JOURNAL ARTICLE
Muhterem Melis Canturk, Gianmarco D'Ancona, Marc Olivier François, Horace Roman
OBJECTIVE: To describe the management of recurrent bowel endometriosis after previous colorectal resection. DESIGN: Surgical video article. The local institutional board review was omitted due to the narration of surgical management. Patient consent was obtained. SETTING: A tertiary referral center. The patient first underwent segmental bowel resection for deep infiltrating endometriosis of the rectum in the ENDORE randomized controlled trial in 2012 and then received a total hysterectomy in 2018...
December 2, 2023: Journal of Minimally Invasive Gynecology
https://read.qxmd.com/read/38007964/robotic-assisted-laparoscopy-for-deep-infiltrating-endometriosis
#24
REVIEW
T Hebert
Deep infiltrative endometriosis is a condition affecting up to 15 % of women of childbearing age, defined by extra uterine location of endometrial like tissues. The symptoms of endometriosis range from severe dysmenorrhea to infertility, chronic pelvic pain, bowel dysfunction and urinary tract involvement to name the most common. Endometriosis has an impact on the quality of life of patients, with personal and social consequences. Although medical treatment is indicated in the first instance, surgery may be necessary...
November 11, 2023: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://read.qxmd.com/read/38006584/irritable-bowel-syndrome-and-endometriosis-diagnosis-similarities-and-nutritional-management
#25
JOURNAL ARTICLE
Cordula Henggeler
Irritable bowel syndrome (IBS) and endometriosis pose significant challenges to affected individuals. IBS, which is a functional gastrointestinal disorder, affects 5-10% of the population, while endometriosis affects 1 in 10 of those assigned female at birth. Despite distinct origins, symptom often overlap, which may lead to misdiagnosis. Diagnosing IBS and endometriosis requires a comprehensive approach. Nutritional management for IBS emphasises self-help strategies, nutritional changes and gut-brain axis modulation...
November 23, 2023: British Journal of Nursing: BJN
https://read.qxmd.com/read/38002788/endo-belly-what-is-it-and-why-does-it-happen-a-narrative-review
#26
REVIEW
Renata Voltolini Velho, Franziska Werner, Sylvia Mechsner
Endometriosis is a chronic inflammatory disease where endometrial-like lesions settle outside the uterus, resulting in extensive inflammatory reactions. It is a complex disease that presents with a range of symptoms, with pain and infertility being the most common. Along with severe dysmenorrhea, cyclic and acyclic lower abdominal pain, cyclic dysuria and dyschezia, dyspareunia, and infertility, there are also nonspecific complaints that can cause confusion and make endometriosis the chameleon among gynecological diseases...
November 19, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37987824/pilot-study-of-treatment-of-patients-with-deep-infiltrative-endometriosis-with-methotrexate-carried-in-lipid-nanoparticles
#27
JOURNAL ARTICLE
Roberta Avila-Tavares, Luciano Gibran, Luiz Gustavo Oliveira Brito, Thauany Martins Tavoni, Manoel Orlando Gonçalves, Edmund Chada Baracat, Raul Cavalcante Maranhão, Sergio Podgaec
OBJECTIVE: Previously, lipid nanoparticles (LDE) injected in women with endometriosis were shown to concentrate in the lesions. Here, the safety and feasibility of LDE carrying methotrexate (MTX) to treat deep infiltrating endometriosis was tested. DESIGN: Prospective pilot study. SETTING: Perola Byington Hospital Reference for Women's Health. SUBJECTS: Eleven volunteers (aged 30-47 years, BMI 26.15 ± 6.50 kg/m2 ) with endometriosis with visual analog scale pelvic pain scores (VAS) > 7 and rectosigmoid lesions were enrolled in the study...
November 21, 2023: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/37982388/a-plain-language-summary-to-learn-about-relugolix-combination-therapy-for-the-treatment-of-pain-associated-with-endometriosis
#28
REVIEW
Linda C Giudice, Sawsan As-Sanie, Juan C Arjona Ferreira, Christian M Becker, Mauricio S Abrao, Bruce A Lessey, Krzysztof Dynowski, Krzysztof Wilk, Yulan Li, Vandana Mathur, Rachel B Wagman, Neil P Johnson
WHAT IS THIS SUMMARY ABOUT?: This is a summary of research studies (known as clinical trials) called SPIRIT 1 and SPIRIT 2. The SPIRIT 1 and SPIRIT 2 studies compared how well a medicine called relugolix combination therapy worked in relieving pain in women with moderate to severe endometriosis compared to a placebo, a pill with no active medication. Endometriosis occurs when tissue similar to what normally lines the uterus grows in other places, such as the ovaries, fallopian tubes, and bowels...
November 2023: Pain Management
https://read.qxmd.com/read/37931893/patient-reported-outcome-measures-used-in-randomized-controlled-trials-following-surgical-intervention-for-endometriosis-a-structured-review-from-the-aagl-practice-guidelines-group
#29
JOURNAL ARTICLE
Jason Abbott, Megan Billow, Thomas Gallant, Loren Hackett, Rosanne M Kho, Blake Knapman, Miguel A Luna Russo, Sarah Maheux-Lacroix, Adriana Meneses Gonzalez, Cecilia Ng, Megan S Orlando, Andrea Sit, Xiao Xu
OBJECTIVE: No consensus currently exists regarding patient-reported outcome measure (PROM) instruments. This structured review was conducted to identify the PROMs used by randomized controlled trials (RCTs) that evaluated surgical treatment in patients with endometriosis. DATA SOURCES: Two parallel searches were conducted by a medical librarian using Ovid MEDLINE, Ovid Embase, and Cochrane Library for RCTs published from 2000 to July 2022. One search focused on studies reporting quality of life (QoL), and the second search focused on studies reporting pain and sexual, bowel, and bladder function...
February 2024: Journal of Minimally Invasive Gynecology
https://read.qxmd.com/read/37916045/endometriosis-resection-using-nerve-sparing-versus-non-nerve-sparing-surgical-techniques
#30
JOURNAL ARTICLE
Shailesh P Puntambekar, Sneha Venkateswaran, Saranya Naidu, Maitreyee Parulekar, Madhavi Patil, Sravya Inampudi, Mihir Chitale, Suyog Bharambe, Aishwarya Puntambekar, Kshitij Manerikar, Seema Puntambekar
INTRODUCTION: Endometriosis is the condition in which there are ectopic endometrial tissues outside the uterine cavity. The use of nerve sparing technique has been well established in the field of oncology, leading to better quality of life following radical oncologic procedures without compromising on the long-term survival. The objective of this study is to compare the quality of life in terms of sexual function and urinary function in women undergoing nerve sparing surgeries for endometriosis and those undergoing non-nerve sparing surgeries...
October 2023: Journal of Obstetrics and Gynaecology of India
https://read.qxmd.com/read/37915732/repetitive-abdominal-pain-in-a-reproductive-aged-woman
#31
Minnie Chan, Yuko Ono, Joji Kotani, Takashi Itou, Yoshikazu Kinoshita
We report a young woman with ileocecal endometriosis who presented with repeated abdominal pain. Under hormonal effects, the endometrium may proliferate and cause bleeding in the bowel wall, leading to cyclical abdominal pain. When recurring abdominal pain is observed in reproductive-aged women, physicians should always be aware of gastrointestinal endometriosis.
November 2023: Clinical Case Reports
https://read.qxmd.com/read/37909040/evidence-of-shared-genetic-factors-in-the-etiology-of-gastrointestinal-disorders-and-endometriosis-and-clinical-implications-for-disease-management
#32
JOURNAL ARTICLE
Fei Yang, Yeda Wu, Richard Hockey, Jenny Doust, Gita D Mishra, Grant W Montgomery, Sally Mortlock
In clinical practice, the co-existence of endometriosis and gastrointestinal symptoms is often observed. Using large-scale datasets, we report a genetic correlation between endometriosis and irritable bowel syndrome (IBS), peptic ulcer disease (PUD), gastro-esophageal reflux disease (GORD), and a combined GORD/PUD medicated (GPM) phenotype. Mendelian randomization analyses support a causal relationship between genetic predisposition to endometriosis and IBS and GPM. Identification of shared risk loci highlights biological pathways that may contribute to the pathogenesis of both diseases, including estrogen regulation and inflammation, and potential therapeutic drug targets (CCKBR; PDE4B)...
October 30, 2023: Cell reports medicine
https://read.qxmd.com/read/37905841/treatment-of-rectosigmoid-endometriosis-by-laparoscopic-reverse-submucosal-dissection-lrsd-the%C3%A2-sydney-partial-thickness-discoid-excision-technique
#33
JOURNAL ARTICLE
Jessica Robertson, Jason Abbott, Sophie Corbett-Burns, Mujahid Bukhari, Shevy Perera, Assem Kalantan, Mikhail Sarofim, Rebecca Chou, Greg Cario, David Rosen, Sarah Choi, Michael Wynn-Williams, George Condous, Danny Chou
BACKGROUND: Laparoscopic reverse submucosal dissection (LRSD) is a standardised surgical technique for removal of rectosigmoid endometriosis which optimises the anatomical dissection plane for excision of endometriotic nodules. AIM: This cohort study assesses the outcomes of the first cohort of women treated by LRSD, for deeply infiltrating rectosigmoid endometriosis. MATERIALS AND METHODS: Primary outcomes assessed were complication rate as defined by the Clavien-Dindo system, and completion of the planned LRSD...
October 31, 2023: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://read.qxmd.com/read/37894065/microbiota-transplant-and-gynecological-disorders-the-bridge-between-present-and-future-treatments
#34
REVIEW
Serena Martinelli, Giulia Nannini, Fabio Cianchi, Fabio Staderini, Francesco Coratti, Amedeo Amedei
Fecal microbiota transplantation (FMT) is a procedure that involves transferring fecal bacteria from a healthy donor to a patients' intestines to restore gut-immunity homeostasis. While FMT was primarily supposed to treat gastrointestinal disorders such as inflammatory bowel disease and irritable bowel syndrome-and especially Clostridium difficile infection (currently the only used as clinical treatment)-recent research has suggested that it may also become a potential treatment for gynecological disorders, including endometriosis and polycystic ovary syndrome (PCOS)...
September 27, 2023: Microorganisms
https://read.qxmd.com/read/37893241/endometriosis-related-chronic-pelvic-pain
#35
REVIEW
Soo Youn Song, Ye Won Jung, WonKyo Shin, Mia Park, Geon Woo Lee, Soohwa Jeong, Sukjeong An, Kyoungmin Kim, Young Bok Ko, Ki Hwan Lee, Byung Hun Kang, Mina Lee, Heon Jong Yoo
Endometriosis, which is the presence of endometrial stroma and glands outside the uterus, is one of the most frequently diagnosed gynecologic diseases in reproductive women. Patients with endometriosis suffer from various pain symptoms such as dysmenorrhea, dyspareunia, and chronic pelvic pain. The pathophysiology for chronic pain in patients with endometriosis has not been fully understood. Altered inflammatory responses have been shown to contribute to pain symptoms. Increased secretion of cytokines, angiogenic factors, and nerve growth factors has been suggested to increase pain...
October 23, 2023: Biomedicines
https://read.qxmd.com/read/37883994/minimally-invasive-surgery-for-deep-endometriosis
#36
JOURNAL ARTICLE
Angela Cho, Chul-Min Park
Deep endometriosis (DE) is endometriotic tissue that invades the peritoneum by >5 mm. Surgery is the treatment of choice for symptomatic DE, and laparoscopic surgery is preferred over laparotomy due to better vision and postoperative pain. In this review, we aimed to collect and summarize recent literature on DE surgery and share laparoscopic procedures for rectovaginal and bowel endometriosis.
October 26, 2023: Obstetrics & Gynecology Science
https://read.qxmd.com/read/37868432/deep-endometriosis-of-the-terminal-ileum-presenting-with-cyclic-recurrent-small-bowel-obstruction
#37
Kristal Ha, Devon Marks, Robert D Bennett, Emad Mikhail
Here, we discuss a case of a 42-year-old premenopausal female who presented with chronic pelvic pain and recurrent small bowel obstruction during menstruation. The patient reported a nine-year history of pelvic pain and a four-year history of episodic small bowel obstruction requiring multiple prior inpatient admissions. During these admissions, the obstruction was managed conservatively with bowel rest and nasogastric tube placement; however, symptoms would recur with subsequent menstrual cycles. Computed tomography showed diffusely dilated loops of small bowel with a transition point in the central anterior pelvis, and magnetic resonance enterography revealed a mass-like area involving small bowel loops in the mid pelvis...
September 2023: Curēus
https://read.qxmd.com/read/37839779/not-all-bad-comes-to-harm-enhanced-recovery-after-surgery-for-rectosigmoid-endometriosis
#38
JOURNAL ARTICLE
Alessandro Arena, Eugenia Degli Esposti, Enrico Pazzaglia, Benedetta Orsini, Irene Cau, Francesca Govoni, Diego Raimondo, Roberto Palermo, Jacopo Lenzi, Paolo Casadio, Renato Seracchioli
STUDY OBJECTIVE: To assess the impact of implementing an enhanced recovery after surgery (ERAS) protocol on the length of hospitalization in women undergoing laparoscopy for rectosigmoid deep infiltrating endometriosis (DIE). DESIGN: A retrospective cohort study. SETTING: An academic referral center for endometriosis and minimally invasive gynecologic surgery. PATIENTS: Women aged between 18 and 50 years scheduled for laparoscopic excision (shaving, full-thickness anterior wall resection, segmental resection) of rectosigmoid endometriosis between February 2017 and February 2023...
January 2024: Journal of Minimally Invasive Gynecology
https://read.qxmd.com/read/37835020/endometriosis-as-an-uncommon-cause-of-intestinal-obstruction-a-comprehensive-literature-review
#39
REVIEW
Florentina Mușat, Dan Nicolae Păduraru, Alexandra Bolocan, Alexandru Constantinescu, Daniel Ion, Octavian Andronic
The prevalence of intestinal endometriosis has been estimated to be between 3% and 37% of all endometriosis cases. Cases of intestinal occlusion due to endometriosis foci on the small bowel and on the large bowel are even rarer, with a reported prevalence of 0.1-0.7%. The aim of this literature review was to summarize the available published evidence on the diagnosis, characteristics, and management of intestinal occlusion due to endometriosis. The search on PubMed retrieved 295 records, of which 158 were rejected following a review of the title and abstract...
October 6, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37813274/fertility-sparing-double-discoid-excision-of-rectosigmoid-deep-endometriosis-under-robotic-integrated-ultrasound-guidance
#40
JOURNAL ARTICLE
Danielle Hardman, Robert D Bennett, Emad Mikhail
OBJECTIVE: To present the use of robotic-integrated ultrasound in performing a double discoid excision of multifocal rectosigmoid endometriosis. DESIGN: Video article STATEMENT OF CONSENT: The patient included in this video gave consent for publication of the video and posting of the video online including social media, the journal website, scientific literature websites (such as PubMed, ScienceDirect, Scopus, etc.) and other applicable sites. SUBJECTS: A 26 year-old G0 with chronic pelvic pain, dyschezia and dysmenorrhea refractory to medical management who desires future fertility...
October 7, 2023: Fertility and Sterility
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