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https://www.readbyqxmd.com/read/29750135/pitfalls-of-ovarian-ablative-magnetic-resonance-guided-radiation-therapy-for-refractory-endometriosis
#1
Shyama Tetar, Anna Bruynzeel, Omar Bohoudi, Theodoor Nieboer, Frank Lagerwaard
In this case presentation, we describe the challenges of performing magnetic resonance-guided radiation therapy (MRgRT) with plan adaptation in a patient with advanced endometriosis, in whom several prior therapeutic attempts were unsuccessful and extensive pelvic irradiation was regarded as being too toxic. Treatment was delivered in two sessions, first for the seemingly only active right ovary, and at a later stage for the left ovary. Some logistical problems were encountered during the preparation of the first treatment, which were subsequently optimized for the second treatment by using transvaginal ultrasound to determine the optimum time point for simulation and delivery...
March 9, 2018: Curēus
https://www.readbyqxmd.com/read/29741687/bowel-surgery-as-a-fertility-enhancing-procedure-in-patients-with-colorectal-endometriosis-methodological-pathogenic-and-ethical-issues
#2
Paolo Vercellini, Paola Viganò, Maria Pina Frattaruolo, Alessandra Borghi, Edgardo Somigliana
Bowel surgery for colorectal endometriosis is being promoted to infertile women without severe sub-occlusive symptoms, with the objective of improving the likelihood of conception. Contrary to rectal shaving, bowel surgery involving full-thickness disk excision and segmental resection entails opening of the intestinal lumen thus increasing the risk of postoperative infectious complications. About 1 in 10 patients undergoing colorectal resection for intestinal endometriosis will experience severe sequelae, including anastomotic dehiscence, rectovaginal fistula formation, and bladder and bowel denervation...
May 7, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29703252/investigation-of-the-slc22a23-gene-in-laryngeal-squamous-cell-carcinoma
#3
Seda Ekizoglu, Didem Seven, Turgut Ulutin, Jalal Guliyev, Nur Buyru
BACKGROUND: Laryngeal squamous cell carcinoma (LSCC) is the second most common cancer of the head and neck. In order to identify differentially expressed genes which may have a role in LSCC carcinogenesis, we performed GeneFishing Assay. One of the differentially expressed genes was the SLC22A23 (solute carrier family 22, member 23) gene. SLC22A23 belongs to a family of organic ion transporters that are responsible for the absorption or excretion of many drugs, xenobiotics and endogenous compounds in a variety of tissues...
April 27, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29678755/colorectal-anastomotic-stenosis-lesson-learned-after-1643-colorectal-resections-for-deep-infiltrating-endometriosis
#4
Elisa Bertocchi, Giuliano Barugola, Marco Benini, Paolo Bocus, Roberto Rossini, Marcello Ceccaroni, Giacomo Ruffo
STUDY OBJECTIVE: To evaluate incidence, risk factors, and treatment of colorectal anastomotic stenosis in patients who underwent rectosigmoid resection for deep infiltrating endometriosis (DIE). DESIGN: A retrospective analysis of prospective database (Canadian Task Force classification III). SETTING: Public Medical Center PATIENTS: All women who underwent laparoscopic rectosigmoid resections for DIE between January 2002 and December 2016...
April 17, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29664797/functional-outcomes-after-rectal-resection-for-deep-infiltrating-pelvic-endometriosis-long-term-results
#5
Suna Erdem, Sara Imboden, Andrea Papadia, Susanne Lanz, Michael D Mueller, Beat Gloor, Mathias Worni
BACKGROUND: Curative management of deep infiltrating endometriosis requires complete removal of all endometriotic implants. Surgical approach to rectal involvement has become a topic of debate given potential postoperative bowel dysfunction and complications. OBJECTIVE: This study aims to assess long-term postoperative evacuation and incontinence outcomes after laparoscopic segmental rectal resection for deep infiltrating endometriosis involving the rectal wall...
April 16, 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29662933/endometriosis-a-rare-cause-of-large-bowel-obstruction
#6
Gonçalo Alexandrino, Luís Carvalho Lourenço, Rita Carvalho, Cisaltina Sobrinho, David Valadas Horta, Jorge Reis
Large bowel obstruction can result in significant morbidity and mortality, especially in cases of acute complete obstruction. There are many possible causes, the most common in adults being colorectal cancer. Endometriosis is a benign disease, and the most affected extragenital location is the bowel, especially the rectosigmoid junction. However, transmural involvement and acute occlusion are very rare events. We report an exceptional case of acute large bowel obstruction as the initial presentation of endometriosis...
March 2018: GE Portuguese Journal of Gastroenterology
https://www.readbyqxmd.com/read/29656149/total-laparoscopic-ureteroneocystostomy-for-ureteral-endometriosis-a-single-center-experience-of-160-consecutive-patients
#7
Marcello Ceccaroni, Matteo Ceccarello, Giuseppe Caleffi, Roberto Clarizia, Stefano Scarperi, Mauro Pastorello, Alberto Molinari, Giacomo Ruffo, Stefano Cavalleri
STUDY OBJECTIVE: To investigate the efficacy of laparoscopic ureteroneocystostomy in patients with deep infiltrating endometriosis (DIE) with ureteral, parametrial, and bowel involvement. DESIGN: Prospective study (Canadian Task Force classification II-2). SETTING: Tertiary referral center for endometriosis care. PATIENTS: One hundred and sixty patients with DIE underwent laparoscopic radical eradication and ureteroneocystostomy between January 2009 and December 2016...
April 12, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29609193/female-sexual-function-in-women-with-suspected-deep-infiltrating-endometriosis
#8
Ryane Vieira Lima, Ana Maria Gomes Pereira, Fernando Bray Beraldo, Cláudia Gazzo, João Alfredo Martins, Reginaldo Guedes Coelho Lopes
OBJECTIVE:  To evaluate the quality of the sexual function of women with suspected deep infiltrating endometriosis. METHODS:  A cross-sectional, observational and prospective study was conducted between May 2015 and August 2016, in which 67 patients with deep infiltrating endometriosis, suspected or diagnosed, were assessed for epidemiological and clinical characteristics, such as pain level through a visual analog scale (VAS), features of deep infiltrating endometriosis lesions and score on the Female Sexual Function Index (FSFI) before the onset of treatment...
March 2018: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29576761/surgical-outcomes-of-laparoscopic-hysterectomy-with-concomitant-endometriosis-without-bowel-or-bladder-dissection-a-cohort-analysis-to-define-a-case-mix-variable
#9
Evelien M Sandberg, Sara R C Driessen, Evelien A T Bak, Nan van Geloven, Judith P Berger, Mathilde J G H Smeets, Johann P T Rhemrev, Frank Willem Jansen
Background: Pelvic endometriosis is often mentioned as one of the variables influencing surgical outcomes of laparoscopic hysterectomy (LH). However, its additional surgical risks have not been well established. The aim of this study was to analyze to what extent concomitant endometriosis influences surgical outcomes of LH and to determine if it should be considered as case-mix variable. Results: A total of 2655 LH's were analyzed, of which 397 (15.0%) with concomitant endometriosis...
2018: Gynecological Surgery
https://www.readbyqxmd.com/read/29563051/obstetrical-outcome-in-women-with-endometriosis-including-spontaneous-hemoperitoneum-and-bowel-perforation-a-systematic-review
#10
REVIEW
Maria Tølbøll Glavind, Maja Vedel Møllgaard, Maja Lundegaard Iversen, Linn Håkonsen Arendt, Axel Forman
Increasing evidence suggests that pregnant women with endometriosis have a higher risk of adverse obstetrical complications. The aim of this study was to systematically review the existing literature on this aspect. A PubMed/MEDLINE search was performed from its inception until September 2017 for studies on adverse obstetrical complications in pregnant women with endometriosis, including: preeclampsia, preterm birth, small for gestational age (SGA), antepartum hemorrhage, spontaneous hemoperitoneum, spontaneous bowel perforation, preterm birth, cesarean delivery, stillbirth and postpartum hemorrhage...
February 21, 2018: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29548620/-epidemiology-and-diagnosis-strategy-cngof-has-endometriosis-guidelines
#11
A Fauconnier, B Borghese, C Huchon, I Thomassin-Naggara, C-A Philip, T Gauthier, N Bourdel, A Denouel, A Torre, P Collinet, M Canis, X Fritel
Based on the best evidence available, we have provided guidelines for clinical practice to target the nature of endometriosis as a disease, the consequences of its natural history on management, and the clinical and imaging evaluation of the disease according to the level of care (primary care, specialized or referral). The frequency of endometriosis is unknown in the general population; endometriosis requires management when it causes symptoms (pain, infertility) or when it affect the function of an organ...
March 13, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29545986/skin-endometriosis-at-the-caesarean-section-scar-a-case-report-and-review-of-the-literature
#12
Fatimah Alnafisah, Shaimaa K Dawa, Sherif Alalfy
Cutaneous endometriosis is one of the rare gynecological conditions. Endometriosis is defined as the presence of endometrial glands and stroma outside the endometrial cavity. It commonly occurs in pelvic sites, such as the ovaries, cul-de-sac, bowel, or pelvic peritoneum. Endometriosis at the incisional scar is difficult to diagnose because of nonspecific symptoms. Usually, patients complain of pain at the site of the incision during menstruation. The main causes in most of the reported cases are obstetrical and gynecological surgeries...
January 13, 2018: Curēus
https://www.readbyqxmd.com/read/29545217/combined-transvaginal-transabdominal-pelvic-ultrasonography-accurately-predicts-the-3-dimensions-of-deep-infiltrating-bowel-endometriosis-measured-after-surgery-a-prospective-study-in-a-specialized-center-diagnostic-value-of-tv-ta-us-for-bowel-die
#13
Alessandra Di Giovanni, Lucia Casarella, Marina Coppola, Domenico Iuzzolino, Marianna Rasile, Mario Malzoni
STUDY OBJECTIVE: To assess sensitivity and accuracy of combined transvaginal/transabdominal ultrasonography for evaluation of deep infiltrating bowel endometriosis nodules measured after surgery. DESIGN: A prospective study (Canadian Task Force classification II.1). SETTING: A Center for Advanced Endoscopic Gynecologic Surgery from January 2014 to December 2016. PATIENTS: All women undergoing laparoscopic surgery and scheduled for segmental resection for clinically suspected bowel endometriosis...
March 12, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29526793/-strategies-and-surgical-management-of-endometriosis-cngof-has-endometriosis-guidelines
#14
H Roman, M Ballester, J Loriau, M Canis, P A Bolze, J Niro, S Ploteau, C Rubod, C Yazbeck, P Collinet, B Rabischong, B Merlot, X Fritel
The article presents French guidelines for surgical management of endometriosis. Surgical treatment is recommended for mild to moderate endometriosis, as it decreases pelvic painful complaints and increases the likelihood of postoperative conception in infertile patients (A). Surgery may be proposed in symptomatic patients with ovarian endometriomas which diameter exceeds 20mm. Cystectomy allows for better postoperative pregnancy rates when compared to ablation using bipolar current, as well as for lower recurrences rates when compared to ablation using bipolar current or CO2 laser...
March 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29514537/are-symptoms-after-a-colorectal-segmental-resection-in-deep-endometriosis-really-improved-the-point-of-view-of-women-before-and-after-surgery
#15
Elisabetta Garavaglia, Annalisa Inversetti, Stefano Ferrari, Paola De Nardi, Massimo Candiani
INTRODUCTION: Bowel endometriosis can cause debilitating symptoms. Surgical colorectal resection is often required for symptomatic relief. Aim of our study was to evaluate quality of life over a one-year follow-up period in patients submitted to a colorectal resection for the treatment of deep endometriosis. Change in intestinal and extra-intestinal symptoms, and reproductive outcome were also evaluated. METHODS: A prospective observational study was conducted on a cohort of 20 women affected by intestinal endometriosis and submitted to a laparoscopic colorectal resection...
March 8, 2018: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29511528/bowel-endometriosis-treated-with-simultaneous-ileocecal-and-rectal-resection
#16
Noritoshi Mizuta, Hirofumi Kosuga, Youichiro Nakamura, Mitsutoshi Ogino, Kozo Tsunemi
A 43-year-old female noticed hematochezia and lower-right abdominal pain during menstruation. Her family doctor detected a mass by computed tomography at the ileocecum. She was referred to our hospital and colonoscopy was performed. We observed extrinsic pressure resulting in mucosal change at the ileocecum. We also observed a submucosal tumor-like lesion at the rectosigmoid. We performed biopsy from both lesions, both were benign. Ileocecal resection and rectal low anterior resection were performed for diagnosis...
February 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29477925/intestinal-obstruction-caused-by-endometriosis-endoscopic-stenting-and-expedited-laparoscopic-resection-avoiding-stoma-a-case-report-and-review-of-the-literature
#17
Pietro Calcagno, Matteo Viti, Alessandro Cornelli, Davide Galli, Corrado D'Urbano
INTRODUCTION: Endometriosis is the growth of endometrium outside the uterine cavity. In 5-15% of cases the disease can affect the colon and small bowel, causing complete obstruction and requiring resection in about 1% of cases. CASE SUMMARY: We describe a case of sigmoid obstruction due to endometriosis in a 38 years old woman with personal history of endometriosis. She was admitted for abdominal pain and constipation. The patient was treated with endoscopic stenting and subsequent laparoscopic sigmoidectomy...
2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29477012/treg-and-nk-cells-related-cytokines-are-associated-with-deep-rectosigmoid-endometriosis-and-clinical-symptoms-related-to-the-disease
#18
Bárbara Yasmin Gueuvoghlanian-Silva, Patrick Bellelis, Denise Frediani Barbeiro, Camila Hernandes, Sergio Podgaec
The aim of this study was to evaluate Treg and NK cells related cytokines in deep infiltrating endometriosis lesions and its relationship with clinical symptoms of the disease. mRNA expression of Transforming Growth Factor Beta (TGFB), Interleukin (IL)10, Interferon Gamma (IFNG), IL7, and IL15 was analyzed by Real-Time PCR in eutopic endometrium and rectosigmoid lesions from 11 women with deep infiltrating endometriosis and in eutopic endometrium from 11 healthy women. IL10, IFNG, and IL7 expression was significantly higher in endometriotic bowel lesions than in eutopic endometrium from women with endometriosis...
April 2018: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/29454144/natural-orifice-specimen-extraction-during-laparoscopic-bowel-resection-for-colorectal-endometriosis-technique-and-outcome
#19
Attila Bokor, Peter Lukovich, Noemi Csibi, Thomas D'Hooghe, Dan Lebovic, Reka Brubel, Janos Rigo
STUDY OBJECTIVE: To present a detailed description of a modified natural orifice specimen extraction (NOSE) colectomy technique. We also report the postoperative outcomes of our prospective case series when compared with conventional laparoscopic bowel resection in a relatively large series of patients. DESIGN: Canadian Task Force classification II-1. SETTING: A university tertiary referral center. PATIENTS: The last 90 consecutive patients in our care with deep infiltrating endometriosis of the bowel are presented in this study...
February 14, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29447372/small-fiber-polyneuropathy-is-prevalent-in-patients-experiencing-complex-chronic-pelvic-pain
#20
Annie Chen, Elise De, Charles Argoff
Objective: To demonstrate the prevalence of small fiber polyneuropathy (SFPN) in patients with refractory chronic pelvic pain (CPP). Design: Retrospective study of prospective database. Subjects: Participants were complex CPP patients recruited from subspecity referral clinics defined as those who were refractory to initial treatment and/or exhibited comorbid pain syndromes at initial presentation. Methods: Comprehensive treatment history for CPP was obtained, and participants referred as above; 3-mm punch biopsies were obtained of the lower extremity and sent to diagnostic reference labs to evaluate for SFPN...
February 13, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
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