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Brain Morphometry

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https://www.readbyqxmd.com/read/28805504/neural-basis-of-altered-earlier-attention-and-higher-order-biological-motion-processing-in-schizophrenia
#1
Yukiko Matsumoto, Hideyuki Takahashi, Jun Miyata, Genichi Sugihara, Toshiya Murai, Hidehiko Takahashi
Schizophrenia patients have impairments of biological motion (BM) perception, which provides critical information about social cognition. Because social cognition is underpinned by attention, the impairments of BM perception in schizophrenia could be partially attributable to altered attention. To elucidate the impairments in attention and social perception in schizophrenia, we investigated the neural basis of impaired BM processing using MRI in respect to attention deficits by eye tracker. Voxel-based morphometry was performed to evaluate the relationship between BM perception and gray matter (GM) volume...
August 14, 2017: Social Neuroscience
https://www.readbyqxmd.com/read/28800325/classification-of-alzheimer-s-disease-and-prediction-of-mild-cognitive-impairment-conversion-using-histogram-based-analysis-of-patient-specific-anatomical-brain-connectivity-networks
#2
Iman Beheshti, Norihide Maikusa, Morteza Daneshmand, Hiroshi Matsuda, Hasan Demirel, Gholamreza Anbarjafari
In this study, we investigated the early detection of Alzheimer's disease (AD) and mild cognitive impairment (MCI) conversion to AD through individual structural connectivity networks using structural magnetic resonance imaging (sMRI) data. In the proposed method, the cortical morphometry of individual gray matter images were used to construct structural connectivity networks. A statistical feature generation approach based on histogram-based feature generation procedure was proposed to represent a statistical-pattern of connectivity networks from a high-dimensional space into low-dimensional feature vectors...
August 8, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28800041/influence-of-preeclampsia-and-late-life-hypertension-on-mri-measures-of-cortical-atrophy
#3
Mekala R Raman, Nirubol Tosakulwong, Samantha M Zuk, Matthew L Senjem, Wendy M White, Julie A Fields, Michelle M Mielke, Timothy G Lesnick, Kent R Bailey, Clifford R Jack, Virginia M Miller, Vesna D Garovic, Kejal Kantarci
OBJECTIVE: Women with a history of preeclampsia are at an increased risk of hypertension and structural brain changes. However, the combined effect of both preeclampsia and late-life hypertension on brain structural changes is not known and was investigated in this study. METHODS: Participants were identified from the population-based Rochester Epidemiology Project cohort. Four groups of women were recruited and investigated in this study: first, women with a history of normotensive pregnancy who have late-life hypertension (n = 8, median age = 62), second, women with a history of normotensive pregnancy who do not have late-life hypertension (n = 32, median age = 59), third, women with a history of preeclampsia who have late-life hypertension (n = 24, median age = 60), and fourth, women with a history of preeclampsia who do not have late-life hypertension (n = 16, median age = 57)...
August 10, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28798299/diabetes-mellitus-is-associated-with-more-severe-brain-spontaneous-activity-impairment-and-gray-matter-loss-in-patients-with-cirrhosis
#4
Yun Fei Wang, Xiang Kong, Guang Ming Lu, Long Jiang Zhang
Recent studies showed many cirrhosis patients may have diabetes mellitus (DM), however, the effect of DM on brain in cirrhotic patients is unclear. This study included 34 cirrhosis patients (17 with DM, 17 without DM) and 17 age-, sex-matched healthy controls. MRI examination and neuropsychological tests were performed. Fractional amplitude of low-frequency fluctuation (fALFF) and voxel-based morphometry algorithms were used to obtain fALFF values and gray matter volume, which were compared and correlated with clinical variables...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28797557/neuroanatomy-of-developmental-dyslexia-pitfalls-and-promise
#5
REVIEW
Franck Ramus, Irene Altarelli, Katarzyna Jednoróg, Jingjing Zhao, Lou Scotto di Covella
Investigations into the neuroanatomical bases of developmental dyslexia have now spanned more than 40 years, starting with the post-mortem examination of a few individual brains in the 60s and 70s, and exploding in the 90s with the widespread use of MRI. The time is now ripe to reappraise the considerable amount of data gathered with MRI using different types of sequences (T1, diffusion, spectroscopy) and analysed using different methods (manual, voxel-based or surface-based morphometry, fractional anisotropy and tractography, multivariate analyses…)...
August 7, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28795429/comparison-of-image-intensity-local-and-multi-atlas-priors-in-brain-tissue-classification
#6
Liping Wang, Frédéric Labrosse, Reyer Zwiggelaar
PURPOSE: Automated and accurate tissue classification in 3D brain Magnetic Resonance images is essential in volumetric morphometry or as a preprocessing step for diagnosing brain diseases. However, noise, intensity inhomogeneity and partial volume effects limit the classification accuracy of existing methods. This paper provides a comparative study on the contributions of three commonly used image information priors for tissue classification in normal brains: image intensity, local and multi-atlas priors...
August 10, 2017: Medical Physics
https://www.readbyqxmd.com/read/28792656/amygdala-and-regional-volumes-in-treatment-resistant-versus-nontreatment-resistant-depression-patients
#7
Anca-Larisa Sandu, Eric Artiges, André Galinowski, Thierry Gallarda, Frank Bellivier, Hervé Lemaitre, Bernard Granger, Damien Ringuenet, Eleni T Tzavara, Jean-Luc Martinot, Marie-Laure Paillère Martinot
BACKGROUND: Although treatment-resistant and nontreatment-resistant depressed patients show structural brain anomalies relative to healthy controls, the difference in regional volumetry between these two groups remains undocumented. METHODS: A whole-brain voxel-based morphometry (VBM) analysis of regional volumes was performed in 125 participants' magnetic resonance images obtained on a 1.5 Tesla scanner; 41 had treatment-resistant depression (TRD), 40 nontreatment-resistant depression (non-TRD), and 44 were healthy controls...
August 9, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28792103/progression-of-regional-atrophy-in-the-left-hemisphere-contributes-to-clinical-and-cognitive-deterioration-in-multiple-sclerosis-a-5-year-study
#8
Paolo Preziosa, Elisabetta Pagani, Sarlota Mesaros, Gianna C Riccitelli, Jelena Dackovic, Jelena Drulovic, Massimo Filippi, Maria A Rocca
In this longitudinal study, we investigated the regional patterns of focal lesions accumulation, and gray (GM) and white matter (WM) atrophy progression over a five-year follow-up (FU) in multiple sclerosis (MS) patients and their association with clinical and cognitive deterioration. Neurological, neuropsychological and brain MRI (dual-echo and 3D T1-weighted sequences) assessments were prospectively performed at baseline (T0) and after a median FU of 4.9 years from 66 MS patients (including relapse-onset and primary progressive MS) and 16 matched controls...
August 9, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28780167/emotion-related-brain-structures-associated-with-trait-creativity-in-middle-children
#9
Kaixiang Zhuang, Yunman Xia, Jiangzhou Sun, Qunlin Chen, Dongtao Wei, Wenjing Yang, Jiang Qiu
Middle childhood is an important period for individual trait shaping, during which children are likely to generate and own their distinct neuromechanism of creative-related traits. This study used voxel-based morphometry (VBM) to identify the brain structures that underlie trait creativity (as measured by the Williams Creativity Aptitude Test) in a sample of typical developing children (aged 9-12, n=64). The results indicated that several emotion-related regions may relate to trait creativity in middle children...
August 2, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28772208/structural-brain-correlates-of-interpersonal-violence-systematic-review-and-voxel-based-meta-analysis-of-neuroimaging-studies
#10
REVIEW
Jelle Lamsma, Clare Mackay, Seena Fazel
Owing to inconsistent nomenclature and results, we have undertaken a label-based review and anatomical likelihood estimation (ALE) meta-analysis of studies measuring the quantitative association between regional grey matter (GM) volume and interpersonal violence. Following PRISMA guidelines, we identified studies by searching 3 online databases (Embase, Medline, PsycInfo) and reference lists. Thirty-five studies were included in the label-based review, providing information for 1288 participants and 86 brain regions...
July 27, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28771634/regional-gray-matter-correlates-of-memory-for-emotion-laden-words-in-middle-aged-and-older-adults-a-voxel-based-morphometry-study
#11
Carina Saarela, Juho Joutsa, Matti Laine, Riitta Parkkola, Juha O Rinne, Mira Karrasch
Emotional content is known to enhance memory in a content-dependent manner in healthy populations. In middle-aged and older adults, a reduced preference for negative material, or even an enhanced preference for positive material has been observed. This preference seems to be modulated by the emotional arousal that the material evokes. The neuroanatomical basis for emotional memory processes is, however, not well understood in middle-aged and older healthy people. Previous research on local gray matter correlates of emotional memory in older populations has mainly been conducted with patients suffering from various neurodegenerative diseases...
2017: PloS One
https://www.readbyqxmd.com/read/28769784/cortical-surface-thickness-in-the-middle-aged-brain-with-white-matter-hyperintense-lesions
#12
Ying Zhuang, Xianjun Zeng, Bo Wang, Muhua Huang, Honghan Gong, Fuqing Zhou
Background and purpose: Previous voxel-based morphometry (VBM) studies have suggested that cortical atrophy is regionally distributed in middle-aged subjects with white matter hyperintense (WMH) lesions. However, few studies have assessed cortical thickness in middle-aged WMH subjects. In this study, we examined cortical thickness as well as cortical morphometry associated with the presence of WMH lesion load in middle-aged subjects. Participants and methods: Thirty-six middle-aged subjects with WMH lesions (WMH group) and without clinical cognitive impairment, and 34 demographically matched healthy control subjects (HCS group) participated in the study...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28763717/regional-decrease-in-gray-matter-volume-is-related-to-body-dissatisfaction-in-anorexia-nervosa
#13
Kunihiro Kohmura, Yasunori Adachi, Satoshi Tanaka, Hiroto Katayama, Miho Imaeda, Naoko Kawano, Kazuo Nishioka, Masahiko Ando, Tetsuya Iidaka, Norio Ozaki
Anorexia nervosa (AN) is a psychiatric disorder, in which the prognosis for some patients is poor. The etiology and effective treatments for AN have not been established. We examined morphometric changes in the brain of AN and clarified how the changes were associated with symptoms and pathophysiology. We enrolled 52 participants: 7 with the restrictive type of AN, 13 with the binge-eating/purging type, 3 with eating disorder not otherwise specified, and 29 healthy controls. Participants underwent T1-weighted MRI...
July 25, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28761571/extending-inferential-group-analysis-in-type-2-diabetic-patients-with-multivariate-glm-implemented-in-spm8
#14
Fábio S Ferreira, João M S Pereira, João V Duarte, Miguel Castelo-Branco
BACKGROUND: Although voxel based morphometry studies are still the standard for analyzing brain structure, their dependence on massive univariate inferential methods is a limiting factor. A better understanding of brain pathologies can be achieved by applying inferential multivariate methods, which allow the study of multiple dependent variables, e.g. different imaging modalities of the same subject. OBJECTIVE: Given the widespread use of SPM software in the brain imaging community, the main aim of this work is the implementation of massive multivariate inferential analysis as a toolbox in this software package...
2017: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/28759805/common-and-distinct-neural-mechanisms-associated-with-the-conscious-experience-of-vicarious-pain
#15
Thomas Grice-Jackson, Hugo D Critchley, Michael J Banissy, Jamie Ward
Vicarious pain perception has been an influential paradigm for investigating the social neuroscience of empathy. This research has highlighted the importance of both shared representations (i.e., involved in both experiencing first-hand physical pain and observing pain) and mechanisms that discriminate between self and other. The majority of this research has been conducted in healthy younger adults using a group-average approach. There are, however, known inter-individual differences that can contribute to vicarious experience...
July 3, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28757243/the-overlapping-brain-region-accounting-for-the-relationship-between-procrastination-and-impulsivity-a-voxel-based-morphometry-study
#16
Peiwei Liu, Tingyong Feng
Procrastination is a prevalent problematic behavior that brings serious consequences, such as lower levels of health, wealth, and well-being. Previous research has verified that impulsivity is one of the traits most strongly correlated with procrastination. However, little is known about why there is a tight behavioral relationship between them. To address this question, we used voxel-based morphometry (VBM) to explore the common neural substrates between procrastination and impulsivity. In line with previous findings, the behavioral results showed a strong behavioral correlation between procrastination and impulsivity...
July 27, 2017: Neuroscience
https://www.readbyqxmd.com/read/28755401/association-between-the-scores-of-the-japanese-version-of-the-brief-assessment-of-cognition-in-schizophrenia-and-whole-brain-structure-in-patients-with-chronic-schizophrenia-a-voxel-based-morphometry-and-diffusion-tensor-imaging-study
#17
Shinsuke Hidese, Miho Ota, Junko Matsuo, Ikki Ishida, Moeko Hiraishi, Toshiya Teraishi, Kotaro Hattori, Hiroshi Kunugi
AIM: The brief assessment of cognition in schizophrenia (BACS) is a concise tool designed to evaluate cognitive deficits in schizophrenia. We examined the possible association between BACS scores and whole-brain structure, as observed using magnetic resonance imaging (MRI) with a relatively large sample. METHODS: The study sample comprised 116 patients with schizophrenia (mean age, 39.3 ± 11.1 years; 66 men) and 118 healthy controls (40.0 ± 13.6; 58 men) who completed the Japanese version of the BACS (BACS-J)...
July 29, 2017: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28750682/behavioural-and-neuroanatomical-correlates-of-auditory-speech-analysis-in-primary-progressive-aphasias
#18
Chris J D Hardy, Jennifer L Agustus, Charles R Marshall, Camilla N Clark, Lucy L Russell, Rebecca L Bond, Emilie V Brotherhood, David L Thomas, Sebastian J Crutch, Jonathan D Rohrer, Jason D Warren
BACKGROUND: Non-verbal auditory impairment is increasingly recognised in the primary progressive aphasias (PPAs) but its relationship to speech processing and brain substrates has not been defined. Here we addressed these issues in patients representing the non-fluent variant (nfvPPA) and semantic variant (svPPA) syndromes of PPA. METHODS: We studied 19 patients with PPA in relation to 19 healthy older individuals. We manipulated three key auditory parameters-temporal regularity, phonemic spectral structure and prosodic predictability (an index of fundamental information content, or entropy)-in sequences of spoken syllables...
July 27, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/28738061/magnetic-resonance-imaging-and-tensor-based-morphometry-in-the-mptp-non-human-primate-model-of-parkinson-s-disease
#19
Michel Modo, William R Crum, Madeline Gerwig, Anthony C Vernon, Priya Patel, Michael J Jackson, Sarah Rose, Peter Jenner, Mahmoud M Iravani
Parkinson's disease (PD) is the second most common neurodegenerative disorder producing a variety of motor and cognitive deficits with the causes remaining largely unknown. The gradual loss of the nigrostriatal pathway is currently considered the pivotal pathological event. To better understand the progression of PD and improve treatment management, defining the disease on a structural basis and expanding brain analysis to extra-nigral structures is indispensable. The anatomical complexity and the presence of neuromelanin, make the use of non-human primates an essential element in developing putative imaging biomarkers of PD...
2017: PloS One
https://www.readbyqxmd.com/read/28736888/alterations-in-cortical-thickness-in-nonmedicated-premature-ejaculation-patients-a-morphometric-mri-study
#20
Fan Guo, Yi-Bin Xi, Ming Gao, Lin Liu, Ning-Bo Fei, Wei Qin, Chen Li, Long-Biao Cui, Fei Yan, Lei Yu, Jian-Lin Yuan, Hong Yin
PURPOSE: Premature ejaculation (PE) is one of the most common sexual dysfunctions in men. However, there has been little research evaluating alterations in brain structure related to PE. We aimed to investigate the characteristics of nonmedicated PE patients in terms of brain morphometry. MATERIALS AND METHODS: The sample consisted with 32 medication-naïve adult men with clinical diagnosed PE and matched 31 healthy controls. All participants received diagnostic interviews and 3...
July 24, 2017: Journal of Magnetic Resonance Imaging: JMRI
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