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https://www.readbyqxmd.com/read/27894060/combined-use-of-tissue-doppler-imaging-and-natriuretic-peptides-as-prognostic-marker-in-asymptomatic-aortic-stenosis
#1
Miquel Gomez Perez, Mireia Ble, Mercedes Cladellas, Lluis Molina, Joan Vila, Alexandra Mas-Stachurska, Laura Higueras-Ortega, Julio Marti-Almor
INTRODUCTION: Tissue Doppler imaging (TDI) and N-terminal-pro-Brain Natriuretic Peptide (NT-proBNP) provides useful non-invasive information about left ventricle filling pressures and both have demonstrated to be a prognostic marker in some valve disease as aortic stenosis (AS). OBJECTIVES: To assess the clinical value of combined TDI and NT-proBNP information in asymptomatic AS patients. MATERIAL AND METHODS: Prospective study of 350 initially asymptomatic moderate to severe AS patients with: Mean aortic valve area 0...
November 10, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27875478/functional-mitral-stenosis-following-mitral-valve-repair
#2
Vincent Chan, Thierry Mesana, Subodh Verma
PURPOSE OF REVIEW: This review summarizes the evidence describing functional mitral stenosis (MS) following surgical mitral valve repair. RECENT FINDINGS: Functional MS is an evolving concept and has been implicated in the repair of functional and organic mitral regurgitation. Following repair of functional mitral regurgitation, an elevation in peak transmitral gradient and pulmonary artery pressure has been observed under physiologic stress. These changes have been associated with worse functional status early after restrictive annuloplasty...
November 19, 2016: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/27865723/mechanisms-of-effort-intolerance-in-patients-with-rheumatic-mitral-stenosis-combined-echocardiography-and-cardiopulmonary-stress%C3%A2-protocol
#3
Michal Laufer-Perl, Yaniv Gura, Jason Shimiaie, Jack Sherez, Gregg S Pressman, Galit Aviram, Simon Maltais, Ricki Megidish, Amir Halkin, Meirav Ingbir, Simon Biner, Gad Keren, Yan Topilsky
OBJECTIVES: This study sought to evaluate mechanisms of effort intolerance in patients with rheumatic mitral stenosis (MS). BACKGROUND: Combined stress echocardiography and cardiopulmonary testing allows assessment of cardiac function, hemodynamics, and oxygen extraction (A-Vo2 difference). METHODS: Using semirecumbent bicycle exercise, 20 patients with rheumatic MS (valve area 1.36 ± 0.4 cm(2)) were compared to 20 control subjects at 4 pre-defined activity stages (rest, unloaded, anaerobic threshold, and peak)...
November 10, 2016: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27861426/mastering-mitral-leaflets-coaptation-after-valve-repair-with-adjustable-mitral-annuloplasty-ring-prove-of-concept-in-mock-loop-study
#4
Piergiorgio Tozzi, Daniel Hayoz, Carlo Antona, Gianfranco B Fiore, Giuseppe Siniscalchi, Enrico Ferrari, Gérard Baeriswyl, Riccardo Vismara
This investigation sought to determine the feasibility of a novel mitral ring designed to reshape mitral annulus on beating heart, after surgery. The mitral ring is intended to improve mitral leaflets coaptation to correct residual and recurrent mitral regurgitations. It could also provide progressive correction of mitral regurgitation. The device was tested in ex vivo beating heart model.The novel mitral ring is selectively deformable in P1, P2 and P3 segments using a dedicated angioplasty-type balloon. The deformation should increase leaflets' coaptation reducing distance between the two leaflets...
November 15, 2016: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/27804157/echocardiographic-assessment-of-prosthetic-mitral-valves-in-children
#5
Taiyu Hayashi, Ryo Inuzuka, Hiroshi Ono, Hitoshi Kato
AIMS: We studied how Doppler-derived hemodynamic parameters in children change as the relative prosthetic mitral valve (PMV) size decreases with somatic growth and evaluated the diagnostic utility of the parameters for detecting PMV obstruction in children. METHODS AND RESULTS: We reviewed 26 echocardiographic examination results of 15 mechanical bileaflet PMVs in 12 children. The median age at echocardiographic examination was 6.6 (0.6-18.1) years. The PMV functioned normally in 24 examinations but was obstructed due to thrombosis in two cases...
November 2, 2016: Echocardiography
https://www.readbyqxmd.com/read/27798059/quality-of-life-after-mitral-valve-intervention
#6
Matthew K H Tan, Omar A Jarral, Elizabeth H E Thong, Emaddin Kidher, Rakesh Uppal, Prakash P Punjabi, Thanos Athanasiou
Advancements in surgical technique and understanding of the pathophysiology of mitral valve (MV) dysfunction have led to improved outcomes. Seen as a development beyond measures of morbidity and mortality, health-related quality-of-life (HRQOL) outcome measures are becoming increasingly popular. These measures are important because complications following routine (i.e. low-risk) operations on the MV are uncommon and further markers of outcome are needed. Surgeons are increasingly operating earlier on asymptomatic patients and will need to prove that HRQOL is not impacted...
October 20, 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27777698/poor-outcome-following-percutaneous-balloon-mitral-valvotomy-in-patients-with-atrial-fibrillation
#7
Naser Aslanabadi, Samad Ghaffari, Naser Khezerlouy Aghdam, Masoumeh Ahmadzade, Babak Kazemi, Babak Nasiri, Ahmad Separham, Bahram Sohrabi, Mohamadreza Taban, Arash Aslanabadi
Introduction: Atrial fibrillation (AF) is the most common arrhythmia in patients with mitral stenosis (MS) and it may increase complications and decreases success rates of percutaneous balloon mitral valvotomy (PBMV). This study aimed to investigate the short and long term results of PBMV in patients with AF compared to sinus rhythm (SR). Methods: In this cross sectional study, 1000 patients with MS who had undergone PBMV between 1999 and 2013 were enrolled including 585 and 415 patients with AF and SR respectively...
2016: Journal of Cardiovascular and Thoracic Research
https://www.readbyqxmd.com/read/27747929/red-blood-cell-distribution-width-hematology-and-serum-biochemistry-in-dogs-with-echocardiographically-estimated-precapillary-and-postcapillary-pulmonary-arterial-hypertension
#8
E Mazzotta, C Guglielmini, G Menciotti, B Contiero, M BaronToaldo, M Berlanda, H Poser
BACKGROUND: Red blood cell distribution width (RDW) is a quantitative measurement of anisocytosis. RDW has prognostic value in humans with different cardiovascular and systemic disorders, but few studies have investigated this biomarker in dogs. OBJECTIVES: To compare the RDW in dogs with precapillary and postcapillary pulmonary hypertension (PH) and a control population of dogs and to correlate RDW with demographic, echocardiographic, and laboratory variables. ANIMALS: One hundred and twenty-seven client-owned dogs including 19 healthy dogs, 82 dogs with myxomatous mitral valve disease (50 dogs without PH and 32 dogs with postcapillary PH), and 26 dogs with precapillary PH...
November 2016: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/27709537/impact-of-preprocedural-atrial-fibrillation-on-immediate-and-long-term-outcomes-after-successful-percutaneous-mitral-valvuloplasty-of-significant-mitral-stenosis
#9
Shiro Miura, Takeshi Arita, Takenori Domei, Kyohei Yamaji, Yoshimitsu Soga, Makoto Hyodo, Shinichi Shirai, Kenji Ando
Optimal time to perform percutaneous mitral valvuloplasty (PMV) for patients with significant mitral stenosis (MS) and atrial fibrillation (AF) remains controversial. We sought to identify prognostic factors and evaluate long-term clinical outcomes after PMV of 77 consecutive patients with MS with a mitral valve area (MVA) <1.5 cm(2). According to baseline heart rhythm, these patients were divided into sinus rhythm (SR; n = 24) and AF (n = 53) groups. The study endpoint was defined as a composite of all-cause mortality, admission for heart failure, mitral valve surgery, repeated PMV, and major cerebral vascular accident during follow-up...
October 5, 2016: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/27692768/concept-of-an-expandable-cardiac-valve-for-surgical-implantation-in-infants-and-children
#10
Sitaram M Emani, Breanna L Piekarski, David Zurakowski, Christopher A Baird, Audrey C Marshall, James E Lock, Pedro J Del Nido
BACKGROUND: Options for cardiac valve replacement in children are limited to fixed-diameter prostheses that do not accommodate for somatic growth. An externally stented bovine jugular vein graft has been modified for surgical valve replacement in pediatric patients, with the intention of subsequent valve expansion in the catheterization laboratory as the child grows. METHODS: Pediatric patients at a single institution who underwent surgical implantation of an expandable bovine jugular vein valve between 2010 and 2014 were reviewed retrospectively...
August 31, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27640048/mitral-valve-in-valve-and-valve-in-ring-technical-aspects-and-procedural-outcomes
#11
Danny Dvir, John Webb
There is a growing practice of transcatheter treatment of failed mitral valves after cardiac surgery, including valve-in-valve and valve-in-ring. Although commonly successful, these procedures can be associated with device malposition (including delayed malposition) and elevated post-procedural gradients (especially when performed inside small surgical valves). Valve-in-ring procedures have elevated risks of left ventricular outflow tract obstruction and post-procedural regurgitation. Careful patient selection and meticulous evaluation of patient anatomy and surgical implant characteristics are essential to achieve optimal clinical results with mitral valve-in-valve and valve-in-ring implantation...
September 18, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27600454/the-echocardiography-of-replacement-heart-valves
#12
REVIEW
John B Chambers
This is a practical description of how replacement valves are assessed using echocardiography. Normal transthoracic appearances including normal variants are described. The problem of differentiating normal function, patient-prosthesis mismatch and pathological obstruction in aortic replacement valves with high gradients is discussed. Obstruction and abnormal regurgitation is described for valves in the aortic, mitral and right-sided positions and when to use echocardiography in suspected infective endocarditis...
September 2016: Echo Research and Practice
https://www.readbyqxmd.com/read/27595683/progressive-intermediate-term-improvement-in-ventricular-and-atrioventricular-interaction-after-transcatheter-pulmonary-valve-replacement-in-patients-with-right-ventricular-outflow-tract-obstruction
#13
Fatima I Lunze, Babar S Hasan, Kimberlee Gauvreau, David W Brown, Steven D Colan, Doff B McElhinney
BACKGROUND: Relief of postoperative right ventricular outflow tract (RVOT) obstruction with transcatheter pulmonary valve replacement (TPVR) results in functional improvement in the short term which we investigated at baseline (BL), early follow-up (FU), and midterm FU after TPVR. METHODS: Echocardiography and cardiopulmonary exercise testing were performed at BL and at early (median 6 months) and midterm FU (median 2.5years) after TPVR. RESULTS: Patients with RVOT obstruction (n=22, median age 17years) were studied...
September 2016: American Heart Journal
https://www.readbyqxmd.com/read/27587470/haemodynamic-improvement-of-older-previously-replaced-mechanical-mitral-valves-by-removal-of-the-subvalvular-pannus-in-redo-cardiac-surgery
#14
Jong Hun Kim, Tae Youn Kim, Jong Bum Choi, Ja Hong Kuh
Patients requiring redo cardiac surgery for diseased heart valves other than mitral valves may show increased pressure gradients and reduced valve areas of previously placed mechanical mitral valves due to subvalvular pannus formation. We treated four women who had mechanical mitral valves inserted greater than or equal to 20 years earlier and who presented with circular pannus that protruded into the lower margin of the valve ring but did not impede leaflet motion. Pannus removal improved the haemodynamic function of the mitral valve...
September 1, 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27585507/transcatheter-edge-to-edge-treatment-of%C3%A2-functional-tricuspid-regurgitation-in%C3%A2-an%C3%A2-ex%C3%A2-vivo-pulsatile-heart-model
#15
Riccardo Vismara, Guido Gelpi, Santosh Prabhu, Paolo Romitelli, Lauren G Troxler, Andrea Mangini, Claudia Romagnoni, Monica Contino, Dylan T Van Hoven, Federico Lucherini, Michal Jaworek, Alberto Redaelli, Gianfranco B Fiore, Carlo Antona
BACKGROUND: Although associated with left heart pathologies, functional tricuspid regurgitation (FTR) is often left untreated during left heart surgery. Hence, owing to its degenerative character, reoperation is often needed, encompassing an impressive (25% to 35%) mortality rate. Thus transcatheter approaches to FTR are raising great interest. OBJECTIVES: The authors evaluated the post-treatment effectiveness of the edge-to-edge technique using the percutaneous mitral valve repair device in an ex vivo pulsatile model of FTR...
September 6, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27567136/medical-management-%C3%AE-blocker-%C3%A2-disopyramide-of-left-ventricular-outflow-gradient-secondary-to-systolic-anterior-motion-of-the-mitral-valve-after-repair
#16
Devin W Kehl, Florian Rader, Charles Pollick, Alfredo Trento, Robert J Siegel
Systolic anterior motion of the mitral valve (SAM) occurs intraoperatively after mitral valve repair (MVRr) in up to 14% of cases and typically resolves in the operating room with conservative measures. Less commonly SAM may also occur in the early or late postoperative period. The clinical course and optimal management of such cases is poorly defined, but reoperation is common. We describe our experience using disopyramide to successfully treat postoperative SAM refractory to beta blockade. Seven patients were retrospectively identified with mitral valve prolapse who underwent MVRr from 2003 to 2015 and were found during follow-up to have severe SAM with a left ventricular outflow tract (LVOT) gradient not observed intraoperatively...
October 1, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27565947/match-and-mismatch-between-opening-area-and-resistance-in-mild-and-moderate-rheumatic-mitral-stenosis
#17
Ibtesam Ibrahim El-Dosouky
BACKGROUND: Mitral valve resistance (MVR) is a hemodynamic consequence of mitral stenosis (MS), but it has no clear threshold with a shortage of data to be reliable. We aimed to investigate match and mismatch between opening area and resistance especially in patients with moderate and mild MS. METHODS: This study comprised 88 patients with moderate and mild rheumatic MS. Transthoracic echocardiographic study estimated the following: mitral valve area (MVA) by both planimetry (2D) and pressure half-time (PHT), mitral valve score (MVS), mean transmitral pressure gradient (MPG), diastolic filling time (DFT), left ventricular out flow tract diameter (LVOTd) and velocity-time integral (LVOTvti), and MVR = MPG/aortic flow ratio [(LVOTd) (LVOTvti)/DFT] in dynes·s/cm(5) ...
August 26, 2016: Echocardiography
https://www.readbyqxmd.com/read/27545664/effectiveness-of-alcohol-septal-ablation-versus-transaortic-extended-myectomy-in-hypertrophic-cardiomyopathy-with-midventricular-obstruction
#18
Yin-Jian Yang, Chao-Mei Fan, Jin-Qing Yuan, Shui-Yun Wang, Yun-Hu Song, Shu-Bin Qiao, Shi-Jie You, Zhi-Min Wang, Fu-Jian Duan, Yi-Shi Li
OBJECTIVES: Investigate the effectiveness of alcohol septal ablation (ASA) and transaortic extended myectomy (TEM) in hypertrophic cardiomyopathy (HCM) with midventricular obstruction (MVO). BACKGROUND: MVO is less common than subaortic obstruction. Data on the effectiveness of ASA and TEM in MVO are lacking. METHODS: The clinical profiles of 22 patients undergoing ASA and 37 patients undergoing TEM were compared. No patient had apical aneurysm, abnormal chordae, mitral valve replacement or repair...
December 2016: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/27537190/transcatheter-mitral-valve-implantation-30-day-outcome-of-first-in-man-experience-with-an-apically-tethered-device
#19
Cesare Quarto, Simon Davies, Alison Duncan, Alistair Lindsay, Georg Lutter, Lucian Lozonschi, Neil Moat
OBJECTIVE: A small number of transcatheter mitral valve implants (TMVIs) have been reported using devices designed to treat secondary mitral regurgitation (MR). However, MR has many etiologies, and patients have a broad spectrum of annular size, geometry, and lesions. There are a number of technical challenges for TMVI including left ventricular outflow tract obstruction and paravalvular MR. Thirty days' outcome of first-in-man implants with a novel TMVI device is reported. METHODS: The Tendyne TMVI system consists of a porcine pericardial valve in a tethered nitinol frame...
May 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/27523403/assessment-of-the-melody-valve-in-the-mitral-position-in-young-children-by-echocardiography
#20
Lindsay R Freud, Gerald R Marx, Audrey C Marshall, Wayne Tworetzky, Sitaram M Emani
OBJECTIVES: Mitral valve replacement (MVR) in young children is limited by the lack of small prostheses. Our institution began performing MVR with modified, surgically placed, stented jugular vein grafts (Melody valve) in 2010. We sought to describe key echocardiographic features for pre- and postoperative assessment of this novel form of MVR. METHODS: The pre- and postoperative echocardiograms of 24 patients who underwent Melody MVR were reviewed. In addition to standard measurements, preoperative potential measurements of the mitral annulus were performed whereby dimensions were estimated for Melody sizing...
July 25, 2016: Journal of Thoracic and Cardiovascular Surgery
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