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mitral valve gradients

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https://www.readbyqxmd.com/read/28921420/causes-of-an-increased-pressure-gradient-through-the-left-ventricular-outflow-tract-a-west-coast-experience
#1
Sayuki Kobayashi, Yoshihiko Sakai, Isao Taguchi, Hiroto Utsunomiya, Takahiro Shiota
BACKGROUND: Left ventricular outflow tract obstruction (LVOTO) occurs from not only obstructive hypertrophic cardiomyopathy but also other conditions such as sigmoid septum or post mitral valve repair. However, the changes of the LVOT pressure gradient (LVOT PG) in LVOTO with various conditions remain unclear. METHODS: The clinical characteristics and echocardiographic parameters of 73 patients with LVOT PG ≥50 mmHg at rest on Doppler ultrasound were retrospectively investigated...
September 18, 2017: Journal of Echocardiography
https://www.readbyqxmd.com/read/28855450/clinical-implication-of-transaortic-mitral-pannus-removal-during-repeat-cardiac-surgery-for-patients-with-mechanical-mitral-valve
#2
Byungjoon Park, Kiick Sung, Pyo Won Park
BACKGROUND: This study aimed to evaluate the safety and feasibility of transaortic mitral pannus removal (TMPR).Methods and Results:Between 2004 and 2016, 34 patients (median age, 57 years; 30 women) with rheumatic disease underwent pannus removal on the ventricular side of a mechanical mitral valve through the aortic valve during reoperation. The median time interval from the previous surgery was 14 years. TMPR was performed after removal of the mechanical aortic valve (n=21) or diseased native aortic valve (n=11)...
August 31, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28838478/2-year-outcomes-after-transcatheter%C3%A2-mitral-valve-replacement
#3
Ander Regueiro, Jian Ye, Neil Fam, Vinayak N Bapat, François Dagenais, Mark D Peterson, Stephan Windecker, John G Webb, Josep Rodés-Cabau
OBJECTIVES: This study sought to determine late (2-year) outcomes following transcatheter mitral valve replacement (TMVR) with the FORTIS valve (Edwards Lifesciences, Irvine, California). BACKGROUND: No data exist on long-term clinical outcomes following TMVR in patients with severe native mitral regurgitation (MR). METHODS: This multicenter registry included consecutive patients with severe MR who underwent TMVR with the FORTIS valve under a compassionate clinical use program...
August 28, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28838477/transcatheter-mitral-valve-implantation-using-the-highlife-system
#4
Marco Barbanti, Nicolò Piazza, Sarah Mangiafico, Jean Buithieu, Sabine Bleiziffer, Giuseppe Ronsivalle, Salvatore Scandura, Angelo Giuffrida, Antonio Popolo Rubbio, Massimo Mazzamuto, Carmelo Sgroi, Rüdiger Lange, Corrado Tamburino
OBJECTIVES: This study is the first report of 2 cases of HighLife (HighLife, Paris, France) implantation in humans. BACKGROUND: Transcatheter mitral valve implantation represents a promising approach to treating mitral regurgitation in patients at increased risk of perioperative mortality. The HighLife transcatheter mitral valve is a 2-component system. The valve is implanted in the mitral position and is anchored by interacting and then reaching an equilibrium position with a previously positioned subannular implant...
August 28, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28838360/transcatheter-mitral-valve-replacement-for-degenerated-bioprosthetic-valves-and%C3%A2-failed%C3%A2-annuloplasty-rings
#5
MULTICENTER STUDY
Sung-Han Yoon, Brian K Whisenant, Sabine Bleiziffer, Victoria Delgado, Niklas Schofer, Lena Eschenbach, Buntaro Fujita, Rahul Sharma, Marco Ancona, Ermela Yzeiraj, Stefano Cannata, Colin Barker, James E Davies, Antonio H Frangieh, Florian Deuschl, Tomaz Podlesnikar, Masahiko Asami, Abhijeet Dhoble, Anthony Chyou, Jean-Bernard Masson, Harindra C Wijeysundera, Daniel J Blackman, Rajiv Rampat, Maurizio Taramasso, Enrique Gutierrez-Ibanes, Tarun Chakravarty, Guiherme F Attizzani, Tsuyoshi Kaneko, S Chiu Wong, Horst Sievert, Fabian Nietlispach, David Hildick-Smith, Luis Nombela-Franco, Lenard Conradi, Christian Hengstenberg, Michael J Reardon, Albert Markus Kasel, Simon Redwood, Antonio Colombo, Saibal Kar, Francesco Maisano, Stephan Windecker, Thomas Pilgrim, Stephan M Ensminger, Bernard D Prendergast, Joachim Schofer, Ulrich Schaefer, Jeroen J Bax, Azeem Latib, Raj R Makkar
BACKGROUND: Limited data exist regarding transcatheter mitral valve replacement (TMVR) for patients with failed mitral valve replacement and repair. OBJECTIVES: This study sought to evaluate the outcomes of TMVR in patients with failed mitral bioprosthetic valves (valve-in-valve [ViV]) and annuloplasty rings (valve-in-ring [ViR]). METHODS: From the TMVR multicenter registry, procedural and clinical outcomes of mitral ViV and ViR were compared according to Mitral Valve Academic Research Consortium criteria...
August 29, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28828046/modern-use-of-echocardiography-in-transcatheter-aortic-valve-replacement-an-up-date
#6
Cristina Caldararu, Serban Balanescu
Echocardiography is the cornerstone in the diagnosis of any valvular heart disease. The accurate diagnosis of aortic stenosis, the left ventricle function and the other heart valves evaluation are currently done by ultrasound alone. Prosthetic valve choice and dimensions prior to implantation can be done solely by proper use of echocardiography. The emergence of new methods to cure aortic stenosis such as trans-catheter aortic valve replacement (TAVR) emphasized the diagnostic value of cardiac ultrasound. The usefulness of echocardiography in TAVR can be divided in the baseline assessment (common to patients treated by conventional surgery), intra-procedural guidance of valve deployment and post-procedural follow-up...
December 2016: Mædica
https://www.readbyqxmd.com/read/28826894/usefulness-of-mitral-valve-prosthetic-or-bioprosthetic-time-velocity-index-ratio-to-detect-prosthetic-or-bioprosthetic-mitral-valve-dysfunction
#7
Sushil Allen Luis, Lori A Blauwet, Himabindu Samardhi, Cathy West, Ramila A Mehta, Chris R Luis, Gregory M Scalia, Fletcher A Miller, Darryl J Burstow
This study aimed to investigate the utility of transthoracic echocardiographic (TTE) Doppler-derived parameters in detection of mitral prosthetic dysfunction and to define optimal cut-off values for identification of such dysfunction by valve type. In total, 971 TTE studies (647 mechanical prostheses; 324 bioprostheses) were compared with transesophageal echocardiography for evaluation of mitral prosthesis function. Among all prostheses, mitral valve prosthesis (MVP) ratio (ratio of time velocity integral of MVP to that of left ventricular outflow tract; odds ratio [OR] 10...
July 25, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28822667/doppler-parameters-derived-from-transthoracic-echocardiography-accurately-detect-bioprosthetic-mitral-valve-dysfunction
#8
Ryan J Spencer, Ken G Gin, Michael Y C Tsang, Teresa S M Tsang, Parvathy Nair, Pui K Lee, John Jue
BACKGROUND: Detecting bioprosthetic mitral valve dysfunction on transthoracic echocardiography can be challenging because of acoustic shadowing of regurgitant jets and a wide normal range of transvalvular gradients. Several studies in mechanical mitral valves have demonstrated the utility of the transthoracically derived parameters E (peak early mitral inflow velocity), pressure half-time, and the ratio of mitral inflow velocity-time integral (VTIMV) to left ventricular outflow tract velocity-time integral (VTILVOT) in detecting significant prosthetic dysfunction...
August 16, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28811765/regression-of-right-ventricular-systolic-pressure-after-successful-percutaneous-mitral-commissurotomy-in-patients-with-isolated-severe-mitral-stenosis
#9
Shah Zeb, Tariq Ashraf, Muhammad Hashim, Syed Nadeem Hassan Rizvi
OBJECTIVE: To know the regression of right ventricular pressure after successful percutaneous transluminalmitral commissurotomy (PTMC) in patients with severe isolated mitral stenosis. METHODS: This descriptive study was performed in inpatient and outpatient department of National Institute of Cardiovascular Disease from 1(st) February 2016 to 31(st) August 2016. Echocardiography of all patients with successful PTMC were recorded 24 hours and 06 months following PTMC to see for Regression of right ventricular pressure along with other baseline echocardiographic parameters...
May 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28805039/unnatural-milieu-thrombus-after-transcatheter-mitral-valve-replacement
#10
EDITORIAL
Jaffar M Khan, Robert J Lederman
What the article teaches Transcatheter heart valve thrombosis in the mitral position causes increased valve gradients, valve dysfunction, and symptoms, and may be associated with lack of therapeutic anticoagulation. How it will impact practice Anticoagulation with a vitamin K antagonist should be considered in all patients undergoing transcatheter mitral valve replacement. What new research/study would help answer the question posed Efficacy, optimal duration, and safety of anticoagulation therapy, balancing reduced thrombosis against increased bleeding risk, needs to be assessed in larger cohort studies and prospective trials...
August 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28792140/effect-of-patient-prosthesis-mismatch-in-aortic-position-on-late-onset-tricuspid-regurgitation-and-clinical-outcomes-after-double-valve-replacement
#11
Seung Hyun Lee, Young Nam Youn, Byung Chul Chang, Hyun Chel Joo, Sak Lee, Kyung Jong Yoo
PURPOSE: Significant late-onset tricuspid regurgitation (TR) is unfortunately common after double valve replacement (DVR); however, its underlying factors remain undefined. We evaluated the effect of aortic patient-prosthesis mismatch (PPM) on late-onset TR and clinical outcomes after DVR. MATERIALS AND METHODS: Of the 2392 consecutive patients who underwent aortic valve replacement between January 1990 and May 2014 at our institution, we retrospectively studied 462 patients who underwent DVR (excluding concomitant tricuspid valvular annuloplasty or replacement)...
September 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/28790250/-usefulness-of-balloon-aortic-valvuloplasty-for-determining-the-operative-procedure-in-a-patient-with-severe-aortic-stenosis-complicated-with-secondary-mitral-regurgitation-report-of-a-case
#12
Kenichi Kamiya, Akira Furuta, Ryoi Okano, Haruki Tanaka, Masaomi Fukusumi, Tadamasa Miyauchi, Takeo Tedoriya
A 59-year-old man on chronic hemodialysis presented with severe aortic stenosis(AS) and moderate mitral regurgitation (MR). Although aortic valve replacement was scheduled, his status deteriorated into New York Heart Association(NYHA) class III heart failure due to the exacerbation of AS and concomitant MR. Double valve replacement was considered to be too high risk for the patient, and balloon aortic valvuloplasty(BAV) was initially performed. As a result, the mean pressure gradient of the aortic valve decreased from 65 to 28 mmHg and the mean pulmonary pressure also from 52 to 33 mmHg...
August 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28790238/-early-postoperative-hemodynamics-of-mitral-valvuloplasty-using-colvin-galloway-future-band
#13
Ryosuke Funahashi, Yukikatsu Okada, Takashi Muro, Hitoshi Inanami, Tomoyuki Takemoto
The Colvin-Galloway( CG) Future annuloplasty band is a new semirigid partial band, which was introduced in 2012 in Japan. A total of 60 consecutive patients who underwent mitral valve repair with the CG Future Band were assessed by echocardiography in terms of residual mitral regurgitation and diastolic mitral function postoperatively. Intraoperative 3-dimensional echocardiography beautifully demonstrated the physiological change of the aortic curtain during the cardiac cycle. 30 mm was used in 18 patients, 32 mm in 17, 28 mm in 15, 34 mm in 5, 36 mm in 2, and 26 mm in 2...
August 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28780576/mechanical-and-surgical-bioprosthetic-valve-thrombosis
#14
REVIEW
Wei Yao Lim, Guy Lloyd, Sanjeev Bhattacharyya
Valve thrombosis can occur in mechanical prosthetic valves and is increasingly recognised in transcatheter and surgically implanted bioprosthetic valves. The risk of thrombosis of mechanical valves is higher in the mitral position compared with aortic position and in older generation valves (ball and cage valves). There is a wide spectrum of presentation from the asymptomatic patient to those with embolic complications or cardiogenic shock. A combination of transthoracic and transesophageal echocardiography is required to assess the haemodynamic effect of thrombosis (valve gradients and area), leaflet motion and thrombus size...
August 5, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28760473/transapical-mitral-valve-implantation-for-native-mitral-valve-stenosis-using-a-balloon-expandable-prosthesis
#15
Philipp Kiefer, Thilo Noack, Joerg Seeburger, Alexandro Hoyer, Axel Linke, Norman Mangner, Lukas Lehmkuhl, Friedrich Wilhelm Mohr, David Holzhey
BACKGROUND: Transcatheter mitral valve implantation (TMVI) is still in its infancy and is mainly limited to valve-in-valve or valve-in-ring implantations. We present the early experience with TMVI for severe calcified native MV stenosis. METHODS: Between January 2014 and June 2015, 6 of 11 patients screened (mean age, 77.4 ± 6.3 years; 66% men) with severe native mitral valve (MV) stenosis (mean gradient [Pmean], 11.1 ± 2.1 mm Hg; mean effective orifice area [EOA], 0...
July 28, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28712559/impact-of-percutaneous-mitral-valvuloplasty-on-left-ventricular-function-in-patients-with-mitral-stenosis-assessed-by-3d-echocardiography
#16
William Antonio M Esteves, Lucas Lodi-Junqueira, Juliana Rodrigues Soares, Guilherme Rafael Sant'Anna Athayde, Gabriela Assunção Goebel, Lucas Amorim Carvalho, Xin Zeng, Judy Hung, Timothy C Tan, Maria Carmo Pereira Nunes
BACKGROUND: The status of intrinsic left ventricular (LV) contractility in patients with isolated rheumatic mitral stenosis (MS) has been debated. The acute changes in loading conditions after percutaneous mitral valvuloplasty (PMV) may affect LV performance. We aimed to examine the acute effects of PMV on LV function and identify factors associated with LV ejection fraction (LVEF) changes, and determinants of long-term events following the procedure. METHODS: One hundred and forty-two patients who underwent PMV for symptomatic rheumatic MS (valve area of 0...
June 23, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28697003/the-respect-rather-than-resect-principle-in-mitral-valve-repair-the-lateral-dislocation-of-the-p2-technique
#17
Marco Zanobini, Gabriella Ricciardi, Francesco Liborio Mammana, Samer Kassem, Paolo Poggio, Alessandro Di Minno, L Cavallotti, Matteo Saccocci
BACKGROUND: Leaflet resection represents the reference standard for surgical treatment of mitral valve (MV) regurgitation. New approaches recently proposed place emphasis on respecting, rather than resecting, the leaflet tissue to avoid the drawbacks of the 'resection' approach. OBJECTIVES: The lateral dislocation of mid portion of mitral posterior leaflet (P2) technique for MV repair is a nonresectional technique in which the prolapsed P2 segment is sutured to normal P1 segment...
September 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28684438/five-year-follow-up-after-transcatheter-aortic-valve-implantation-for-symptomatic-aortic-stenosis
#18
Ralf Zahn, Nicolas Werner, Ulrich Gerckens, Axel Linke, Horst Sievert, Philipp Kahlert, Rainer Hambrecht, Stefan Sack, Mohamed Abdel-Wahab, Ellen Hoffmann, Uwe Zeymer, Steffen Schneider
OBJECTIVES: Transcatheter aortic valve implantation (TAVI) has been implemented into the care of elderly patients suffering from severe symptomatic aortic stenosis. However, data on long-term follow-up are sparse and predictors of long-term mortality need to be evaluated to better select patients. Therefore, we aimed to analyse predictors of 5-year mortality after TAVI. METHODS: We analysed data from the German Transcatheter Aortic Valve Interventions-Registry. Each of the 27 participating hospitals agreed to include all consecutive TAVI patients at their institution...
July 6, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28683992/assessment-of-mitral-valve-repair-with-exercise-echocardiography-artificial-chordae-vs-leaflet-resection
#19
COMPARATIVE STUDY
Sigurdur Ragnarsson, Johan Sjögren, Martin Stagmo, Per Wierup, Shahab Nozohoor
Mitral valve (MV) repair with artificial chordae (AC) or leaflet resection (LR) is associated with good hemodynamics at rest. The aim of this study was to compare these techniques in terms of exercise capacity and echocardiographic parameters of hemodynamics at rest and peak exercise. We conducted a study in 2015 of 56 patients, who had undergone surgery for degenerative posterior mitral leaflet prolapse between 2005 and 2014 using either AC (n = 24) or LR (n = 32). Clinical data were collected, exercise capacity was measured, and resting echocardiography and peak exercise echocardiography were performed...
April 2017: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28676179/transaortic-edge-to-edge-mitral-valve-repair-for-moderate-secondary-functional-mitral-regurgitation-in-patients-undergoing-aortic-root-valve-intervention
#20
Shiv Kumar Choudhary, Atul Abraham, Amol Bhoje, Parag Gharde, Manoj Sahu, Sachin Talwar, Balram Airan
OBJECTIVE: The present study evaluates the feasibility, safety, and efficacy of edge-to-edge repair for moderate secondary/functional mitral regurgitation in patients undergoing aortic valve/root interventions. METHODS: Sixteen patients underwent transaortic edge-to-edge mitral valve repair. Mitral regurgitation was 2+ in 8 patients and 3+ in 6 patients. Two patients in whom cardiac arrest developed preoperatively had severe (4+) mitral regurgitation. Patients underwent operation for severe aortic regurgitation ± aortic root lesions...
June 13, 2017: Journal of Thoracic and Cardiovascular Surgery
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