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Caterina Neri, Alessandra Familiari, Francesco Preziosi, Chiara Vassallo, Angela Botta, Antonio Lanzone, Brigida Carducci, Alessandro Caruso
BACKGROUND: Labor induction (IOL) is one of the most common procedures performed in obstetrics, accounting for about the 20% of deliveries in the developed countries and it still represents a challenge to obstetricians. PURPOSE: The aim of this study is the comparison between two techniques for induction of Labor (IOL): oral Misoprostol and Propess. MATERIALS AND METHODS: Restrospective study in a single tertiary referral center. Clinical maternal, fetal and neonatal informations were recorded...
January 26, 2018: Minerva Ginecologica
Tove Wallstrom, Hans Jarnbert-Pettersson, David Stenson, Helena Akerud, Elisabeth Darj, Kristina Gemzell-Danielsson, Eva Wiberg-Itzel
Introduction: One great challenge in obstetric care is labor inductions. Misoprostol has advantages in being cheap and stable at room temperature and available in resource-poor settings. Material and Methods: Retrospective cohort study of 4002 singleton pregnancies with a gestational age ≥34 w at Sodersjukhuset, Stockholm, during 2009-2010 and 2012-2013. Previously used methods of labor induction were compared with misoprostol given as a solution to drink, every second hour...
2017: BioMed Research International
Caroline Diguisto, Amélie Le Gouge, Bruno Giraudeau, Franck Perrotin
INTRODUCTION: Induction of labour for prolonged pregnancies (PP) when the cervix is unfavourable is a challenging situation. Cervical ripening by pharmacological or mechanical techniques before oxytocin administration is used to increase the likelihood of vaginal delivery. Both techniques are equally effective in achieving vaginal delivery but excessive uterine activity, which induces fetal heart rate (FHR) anomalies, is more frequent after the pharmacological intervention. We hypothesised that mechanical cervical ripening could reduce the caesarean rate for non-reassuring FHR especially in PP where fetuses are already susceptible to this...
September 14, 2017: BMJ Open
P Coste Mazeau, C Catalan, J-L Eyraud, Y Aubard, T Gauthier
OBJECTIVES: Because, to date in France, 20 % of pregnant women had a scared uterus and because the best mean of cervical ripening is unknown and controversial, we want to evaluate efficacy and safety of dinoprostone for cervical ripening in women with previous cesarean. MATERIALS AND METHODS: We conducted a retrospective unicentric study, from 2010 to 2014, at Limoges regional university hospitals. Two hundred and sixty nine patients, with medical indication for induction of labor and scared uterus, were included and ripened with dinoprostone (Propess(®) and/or Prostine(®))...
February 2017: Gynecologie, Obstetrique, Fertilite & Senologie
Yoo Min Kim, Ju Young Park, Ji-Hee Sung, Suk-Joo Choi, Soo-Young Oh, Cheong-Rae Roh, Jong-Hwa Kim
OBJECTIVE: To evaluate the efficacy and safety of prostaglandin (PG) E2 for preterm labor induction and to investigate the predictive factors for the success of vaginal delivery. METHODS: A retrospective cohort study was performed in women (n=155) at 24+0 to 36+6 weeks of gestation who underwent induction of labor using a PGE2 vaginal pessary (10 mg, Propess) from January 2009 to December 2015. Success rates of vaginal delivery according to gestational age at induction and incidence of intrapartum complications such as tachysystole and nonreassuring fetal heart rate were investigated...
March 2017: Obstetrics & Gynecology Science
Andrew N Sharp, Sarah J Stock, Zarko Alfirevic
OBJECTIVE: To identify the current UK use of outpatient procedures for cervical ripening prior to induction of labour. STUDY DESIGN: Postal survey of consultant led obstetric units within the United Kingdom. A questionnaire was sent by post to 210 NHS consultant led obstetric units within the UK. Units that provided outpatient induction of labour (OP IOL) were asked complete a series of questions defining their protocol for risk stratification and management. RESULTS: The survey had a 78% response rate...
September 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Richard Bernhard Mayer, Peter Oppelt, Omar Shebl, Joachim Pömer, Christina Allerstorfer, Christoph Weiss
OBJECTIVE: Only one phase III trial has been published to date on the efficacy and safety of misoprostol vaginal inserts for inducing labor. The aim of this study was to compare misoprostol inserts with dinoprostone inserts. STUDY DESIGN: This retrospective cohort study evaluated the reduction in time to vaginal delivery and delivery within 24h, in routine clinical work, in 119 labor inductions using a 200-μg misoprostol vaginal insert (Misodel(®); June-October 2014) in comparison with 124 inductions using a 10-mg dinoprostone insert (Propess(®); December 2013-April 2014)...
May 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Y Bayoglu Tekin, U Mete Ural, O Secilmis Kerimoglu, G Balik, F Kir Sahin, E S Guvendag Guven
This retrospective study compared maternal and fetal outcomes after labour induction, using a dinoprostone vaginal pessary (Propess(®)) in midwife-led and obstetrician-led labour management. Labour induction outcomes, delivery mode and rates of admission to the neonatal intensive care unit were compared. A total of 405 women, 40.5% (n = 164) from midwife-led units and 59.5% (n = 241) from an obstetrician-led unit, participated. There was no statistically significant difference between the two groups in caesarean section rate or neonatal intensive care unit admission rates (p = 0...
May 2015: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
W Chen, Y Zhou, X Pu, C Xiao
This study was to investigate the efficiency and safety of vaginal Propess as a methodology for cervical ripening and labour induction in full-term pregnant patients. Women at term with a Bishop's score of < 6 and without any contraindications, to vaginal delivery, or the use of prostaglandin or oxytocin in induction of labour, were divided into three groups: oxytocin group (n = 59), intact membranes (Propess I group; n = 58) and natural rupture (Propess R group; n = 52) groups. The main outcome measures, including change in Bishop's score, induction to delivery interval, total delivery time, rate of vaginal delivery, fetal outcome and maternal complications during induction, were recorded...
April 2014: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
M Petrovic Barbitch, A Gnisci, M Marcelli, M Capelle, B Guidicelli, L Cravello, M Gamerre, A Agostini
OBJECTIVES: To evaluate efficacy and safety of cervical ripening with repeated administration of dinoprostone slow release vaginal pessary (Propess®) in current practice. PATIENTS AND METHODS: An observational study of 111 women who underwent cervical ripening with two Propess® during the study period from 1st July 2007 to 31st October 2011. Modes of delivery, success of cervical ripening, failure of labor induction, maternal and neonatal morbidity were reported...
June 2013: Gynécologie, Obstétrique & Fertilité
Nezahat Öztürk Akay, Deniz Hızlı, Saynur Sarıcı Yılmaz, Serdar Yalvaç, Omer Kandemir
AIMS: The aim of this study was to compare the efficacy of oxytocin and dinoprostone in achieving successful labor induction and vaginal delivery in postterm women with an unfavorable cervix. METHODS: Postterm women with an uncomplicated pregnancy and a Bishop score of ≤6 were randomized to receive either dinoprostone vaginal pessary (Propess®) or low-dose oxytocin. The primary outcomes were the length of the induction-to-delivery period and the incidence of vaginal delivery...
2012: Gynecologic and Obstetric Investigation
N Woodhead, C Tsitlakidis, O A Adenkanmi
No abstract text is available yet for this article.
February 2012: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
A-C Sans-Mischel, C Trastour, C Sakarovitch, J Delotte, E Fontas, A Bongain
UNLABELLED: Since many years, caesarean section rate has increased in France. The purpose of the study was to compare the different French obstetrical attitudes after a prior caesarean section. METHODS: This retrospective study was performed between March 2008 and February 2010. We collected the answers of a majority of maternity centres contacted with an anonymous questionnaire sent by postal, electronic, fax mails. RESULTS: Of the 194 maternity centres which have responded, there were 37 university hospitals and 312 obstetricians: 75...
November 2011: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
Antonella Ferraiolo, Ilaria Dellacasa, Giorgio Bentivoglio, Simone Ferrero, Nicola Ragni
OBJECTIVE: To evaluate patient satisfaction of cervical ripening using dinoprostone (PGE2) by either intravaginal gel or pessary. STUDY DESIGN: A group of 173 nulliparous women requiring cervical ripening were recruited in the study and randomized to receive either intravaginal gel (Prepidil, Upjohn, Milan, Italy [group A]) or intravaginal pessary (Propess, Ferring Pharmaceuticals, Malmö, Sweden [group B]). Before administration of PGE2 and after delivery, the patients answered a questionnaire investigating the anxiety and discomfort caused by cervical ripening...
September 2010: Journal of Reproductive Medicine
A A Calder And I Z Mackenzie
No abstract text is available yet for this article.
1997: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
T Tsernev
No abstract text is available yet for this article.
2002: Akusherstvo i Ginekologii︠a︡
Deniz Karcaaltincaba, Derya Akdag, Omer Kandemir, Serdar Yalvac, Emine Seda Guvendag Guven, Ali Haberal
OBJECTIVE: To investigate the relation between changes in Doppler parameters of fetal and uterine arteries and development of persistent non-reassuring fetal heart rate (FHR) pattern during induction of labor with dinoprostone (Propess) in pregnancies at >or=41 weeks gestation. DESIGN: Prospective cohort study. SETTING: Etlik Zubeyde Hanim Women's Hospital, Turkey. SAMPLE: One hundred forty-one prolonged pregnancies...
2009: Acta Obstetricia et Gynecologica Scandinavica
R K Kalkat, E McMillan, H Cooper, K Palmer
A randomised controlled trial was conducted to compare the clinical efficacy and cost-effectiveness of Dinoprostone Slow Release Pessary (Propess) with Gel (Prostin) for induction of labour (IOL) at term. A total of 120 women requiring IOL at term with no previous uterine surgery and no contraindication to prostaglandins were included. The main outcome measures were efficacy of drug preparations, patient satisfaction and the cost-effectiveness. The secondary outcome measures noted were maternal complications during the labour, type of delivery, the neonate's Apgar scores at birth and 5 min and incidence of significant morbidities...
October 2008: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
M Arduini, C Giri, L Giannone, E Giannone
AIM: The aim of the study was to evaluate the effectiveness and safety of the two different pharmaceutical preparations of dinoprostone: ''Prepidil vs Propess'', in patients with medical and/or obstetrical indications to pharmaceutical induction of labour. METHODS: A retrospective analysis was carried out on 144 patients (82 with Propess vs 62 with Prepidil). INDICATIONS: post-term pregnancy, premature rupture of membranes (PROM), gestational diabetes, gestational-chronic hypertension, intrauterine growth restriction (IUGR),others (fetal macrosomia, oligohydramnios)...
April 2008: Minerva Ginecologica
Carlos Larrañaga-Azcárate, Gema Campo-Molina, Ana Felicitas Pérez-Rodríguez, Miguel Ezcurdia-Gurpegui
BACKGROUND: Retrospective study of 744 women at the Virgen del Camino Hospital in Pamplona concerning two variants for the active treatment of premature rupture of the membranes (PROM). The main purpose of the study was to assess the differences between two variants for the active treatment of PROM at term in pregnant women with negative vaginal-rectal culture screening for Group B Streptococci, and a Bishop test of 4 or less on admission. METHODS: Retrospective study of 744 patients with single pregnancy at term, PROM, and Bishop test <4...
2008: Acta Obstetricia et Gynecologica Scandinavica
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