keyword
https://read.qxmd.com/read/37806026/comparison-of-cesarean-delivery-rates-after-3-methods-of-cervical-ripening-among-obese-women-at-or-after-41%C3%A2-weeks-secondary-analysis-of-two-french-randomized-controlled-trials-magpop-and-cytopro
#21
JOURNAL ARTICLE
Marine Estrade, Caroline Diguisto, Catherine Arnaud, Virginie Ehlinger, Pr Christophe Vayssière
OBJECTIVE: To compare cesarean rates and maternal and neonatal morbidity according to the cervical ripening method used among obese pregnant women requiring induction of labor at or after 41 weeks of gestation. DESIGN: A secondary analysis of two multicenter randomized controlled trials conducted in French maternity units between 2015 and 2018. PARTICIPANTS: 336 women with a body mass index ≥30 kg/m2 , a pregnancy ≥41 weeks, and an induction of labor requiring cervical ripening...
September 24, 2023: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/37660506/safety-of-misoprostol-vs-dinoprostone-for-induction-of-labor-a-systematic-review-and-meta-analysis
#22
REVIEW
Cristina Taliento, Margherita Manservigi, Mara Tormen, Rosaria Cappadona, Irene Piccolotti, Stefano Salvioli, Gennaro Scutiero, Pantaleo Greco
OBJECTIVE: Pharmacological agents such as prostaglandins (dinoprostone and misoprostol) are commonly used to reduce the duration of labor and promote vaginal delivery. However, key safety considerations with its use include an increased risk of uterine rupture, tachysystole and hyperstimulation of pregnant women, which could potentially lead to a non-reassuring fetal heart rate and to fetal hypoxemia. The aim of this systematic review was to assess maternal and fetal outcomes between misoprostol group (PGE1) and dinoprostone group (PGE2) STUDY DESIGN: We search on MEDLINE (PubMed), CINHAL (EBSCOhost), EMBASE, Scopus (Ovid), CENTRAL (January 1, 1998, to December 31, 2022)...
October 2023: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/37653250/evaluation-of-nitric-acid-donor-transdermal-glycerol-trinitrate-patches-for-facilitating-cervical-ripening-a-randomised-controlled-trial
#23
JOURNAL ARTICLE
Sanjoy Kumar Bhattacharyya, Prithwikar Mandal, Sanjib Dutta, Subhadeep Basak, Rumina Bagchi, Alapan Halder
PURPOSE: To evaluate the efficacy and safety of transdermal glycerol trinitrate skin patches as an additive and effective agent for facilitating cervical ripening for labour induction. METHODS: This was a double-blinded prospective randomised clinical trial carried out in a major obstetric unit in India. Women who planned for labour induction were randomly allocated for induction either by combined application of glycerol trinitrate skin patches [GTN patch] and intracervical dinoprostone gel or by the gel only...
August 31, 2023: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/37626622/risk-of-cesarean-delivery-after-vaginal-inserts-with-prostaglandin-analogs-and-single-balloon-catheter-used-for-cervical-ripening-and-induction-of-labor
#24
JOURNAL ARTICLE
Maciej W Socha, Wojciech Flis, Miłosz Pietrus, Mateusz Wartęga
(1) Background: Induction of labor is currently the most frequently performed procedure in modern obstetrics, referring to more than one in five women, and it is postulated that the percentage of labor induction will increase. (2) Methods: In total, 2935 patients in uncomplicated full-term pregnancy fulfilled the study inclusion criteria and underwent induction of labor. Pregnant women were divided into three groups: IOL with Dinoprostone, Misoprostol vaginal suppositories, and Foley catheter. Outcomes, including cesarean section rates, time to delivery, and cesarean section indications, were analyzed...
July 27, 2023: Biomedicines
https://read.qxmd.com/read/37611747/labor-induction-with-a-combined-method-pharmacologic-and-mechanical-a-randomized-controlled-trial
#25
JOURNAL ARTICLE
Rita Polónia-Valente, Susana Costa, Carolina Coimbra, Joana Xavier, Rita Figueiredo, Tiago Ferraz, Ana Paula Machado, Marina Moucho
INTRODUCTION: The aim of this study was to compare the effectiveness of a combined misoprostol-Foley catheter induction of labor protocol against the current guidelines of our department. MATERIAL AND METHODS: A randomized trial was conducted comparing two cervical ripening study groups: combined misoprostol-cervical Foley and the current department practice (misoprostol alone or dinoprostone alone). Women were stratified randomly according to parity for the two intervention groups...
August 21, 2023: Journal of Gynecology Obstetrics and Human Reproduction
https://read.qxmd.com/read/37605669/comparison-of-vaginal-dinoprostone-pessary-with-transcervical-balloon-catheter-plus-vaginal-misoprostol-for-pre-induction-cervical-ripening-a-randomized-trial
#26
JOURNAL ARTICLE
Kanagavarshani M, Vanita Jain, Aashima Arora, Jogender Kumar
Aims and Objectives To compare the safety and efficacy of dinoprostone pessary with Foley plus vaginal misoprostol for cervical ripening. Materials and Methods We randomized 115 women to the pessary or Foley plus misoprostol group. Pessary was inserted for 24 hours, and in the Foley plus misoprostol group, intravaginal misoprostol 25 mcg was administered along with trans-cervical Foley insertion and repeated every six hours to a maximum dose of 100 mcg. Singleton pregnancies requiring labor induction at more than 34 weeks with a Bishop score of <6 were included...
July 2023: Curēus
https://read.qxmd.com/read/37584912/double-balloon-catheter-vs-dinoprostone-pge-2-insert-for-labour-induction-a-meta-analysis-of-2493-pregnancies
#27
REVIEW
Amal M Elhusein, Hammad A Fadlalmola, Raga A Ebrahim, Amani A Mohammed, Salwa A Mohmed, Sara E Mohamed, Rym Hassani, Nagat S Eltaher, Sitelbanat M Ahmed, Rabab K Mansour, Somia J Farg, Hawa I Hamid, Farida R Shaaeldein, Nafesa H Abbo, Shahenda A A Salih, Hamza H A Balola, Eltayeb A Idress, Abdalla M Osman, Suaad A S Omer, Wargaa H Taha, Huda H Abedelwahed
Induction of labor (IOL) is the stimulation of the uterus during pregnancy to begin the onset of labour. Nearly two of five pregnancies require IOL. We compared the effectiveness of double-balloon catheter (DBC) with dinoprostone (PGE-2) insert for labour induction from previous studies. We included randomized controlled trials (RCTs) that compared the safety and efficacy of DBC to PGE-2. To evaluate the studies, we utilized the Cochrane tool for risk of bias assessment. The rates of vaginal birth and cesarean section were the primary outcomes...
April 2023: African Journal of Reproductive Health
https://read.qxmd.com/read/37548500/comparison-of-labor-duration-of-induced-labor-with-dinoprostone-insert-vs-spontaneous-labor
#28
JOURNAL ARTICLE
Katarzyna A Skibinska, Magdalena Kolak, Agnieszka Micek, Hubert Huras, Andrzej Jaworowski
OBJECTIVES: Labor induction is one of the most common procedures in modern obstetrics. One in five pregnant women and 30-40% of women delivering vaginally undergo this procedure. If the cervical status is unfavorable, a ripening process is used prior to induction to shorten the duration of oxytocin administration and maximize the possibility of vaginal birth. The aim of this study was to compare the duration of labor induced with dinoprostone vaginal insert additionally followed by foley catheter to spontaneous labor...
August 7, 2023: Ginekologia Polska
https://read.qxmd.com/read/37513894/results-of-induction-of-labor-with-prostaglandins-e1-and-e2-the-ripe-study-a-real-world-data-analysis-of-obstetrical-effectiveness-and-clinical-outcomes-of-pharmacological-induction-of-labor-with-vaginal-inserts
#29
JOURNAL ARTICLE
Maciej W Socha, Wojciech Flis, Miłosz Pietrus, Mateusz Wartęga
Despite extensive knowledge of the mechanisms responsible for childbirth, the course of labor induction is often unpredictable. Therefore, labor induction protocols using prostaglandin analogs have been developed and tested to assess their effectiveness in labor induction unequivocally. A total of 402 women were collected into two groups-receiving vaginal Misoprostol or vaginal Dinoprostone for induction of labor (IOL). Then, the patients were compared in groups depending on the agent they received and their gestational age...
July 8, 2023: Pharmaceuticals
https://read.qxmd.com/read/37458650/ultrasound-assessment-of-cervical-status-compared-to-the-bishop-score-predicting-the-success-of-labor-induction-using-a-machine-learning-based-model
#30
JOURNAL ARTICLE
A Krsman, Z Grujić, D Čapko, D Dragutinović, B Baturan, A Nikolić, K Antić Trifunović, I Dickov
OBJECTIVE: The main aim of this study was to develop a machine-learning-based model for predicting the success of labor induction (IOL). To that end, the clinical and ultrasound parameters that affect the successfulness of labor induction were assessed. Then, a new ultrasound scoring system (USS) was developed and assessed. PATIENTS AND METHODS: This prospective observational study included 192 term women who underwent induction of labor. First, a wide range of clinical and ultrasound pre-induction parameters were recorded...
July 2023: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/37421158/comparison-of-fetal-safety-of-vaginal-misoprostol-tablet-and-dinoprostone-gel-for-induction-of-labor-an-open-label-randomized-control-trial
#31
JOURNAL ARTICLE
Ajanta Samanta, Bibek Mohan Rakshit, Pallab Kumar Mistri, Arup Chakraborty, Tarasankar Bag, Piyali Das, Arindam Pande
AIM: In modern obstetrics, need of labor induction is increasing along with increased caesarean deliveries. Major contributions for these operative deliveries are due to induction failure. This demands a potent labor-inducing agent. Dinoprostone gel is an established method but having some drawbacks. Misoprostol could be an effective alternative to Dinoprostone, but its fetal safety is not yet well established. This study aimed to evaluate the fetal safety of vaginal Misoprostol tablet by measuring fetal heart rate changes during induction of labor...
July 8, 2023: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/37398821/a-comparative-study-of-the-efficacy-and-safety-of-oral-misoprostol-intravenous-oxytocin-and-intravaginal-dinoprostone-for-labor-induction-in-pakistani-women
#32
JOURNAL ARTICLE
Asad Ullah Wasim, Muhammad Muneeb Khan, Fnu Aneela, Haris Khan, Mirna Denise Díaz Solís, Insha Shabir, Syed Saem Ul Hassan, Umer Bin Tariq
INTRODUCTION: A frequent medical procedure to accelerate labor is the induction of labor. There are different methods of labor induction, including the use of medications such as misoprostol, oxytocin, and dinoprostone. OBJECTIVE: This research compared the effectiveness and safety of oral misoprostol, intravenous oxytocin, and intravaginal dinoprostone for labor induction in Pakistani women. METHODOLOGY: A study was conducted in the Department of Obstetrics and Gynaecology, Hayatabad Medical Complex-Medical Teaching Institute (MTI) and Lady Reading Hospital-MTI, Peshawar, Pakistan, over two years...
May 2023: Curēus
https://read.qxmd.com/read/37385818/comparison-of-the-efficacy-between-controlled-release-dinoprostone-delivery-system-propess-and-cook-s-double-balloon-catheter-plus-oxytocin-a-retrospective-single-center-study-in-japan
#33
JOURNAL ARTICLE
Kenji Imai, Yuki Nozaki, Takafumi Ushida, Sho Tano, Hiroaki Kajiyama, Tomomi Kotani
AIMS: To compare the efficacy of the controlled-release dinoprostone delivery system (PROPESS) and Cook's double balloon catheter (DBC) plus oxytocin as induction treatment. METHODS: A total of 197 term pregnant women with unfavorable cervix were admitted for scheduled induction and enrolled retrospectively (PROPESS, 113; Cook's DBC plus oxytocin, 84). The main birth outcomes were cervical ripening at the treatment-end and 24 h after the treatment-start, and rate of vaginal birth...
June 29, 2023: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/37366476/comparison-of-obstetric-outcomes-between-controlled-release-dinoprostone-vaginal-delivery-system-propess-and-administration-of-oral-dinoprostone-for-labor-induction-in-multiparous-women-at-term
#34
JOURNAL ARTICLE
Nobuko Yokoyama, Shunji Suzuki
OBJECTIVE: The aim of this study was to compare the rate of vaginal delivery and adverse outcomes of a controlled-release dinoprostone vaginal delivery system (PROPESS) and the administration of oral dinoprostone for labor induction in multiparous women at term. METHODS: This retrospective case-controlled study included 92 multiparous pregnant women (46 and 46 in the PROPESS and oral dinoprostone groups, respectively) who required labor induction at ≥37 weeks of gestation...
June 2023: Curēus
https://read.qxmd.com/read/37336231/cervical-osmotic-dilators-versus-dinoprostone-for-cervical-ripening-during-labor-induction-a-systematic-review-and-meta-analysis-of-14-controlled-trials
#35
JOURNAL ARTICLE
Abdulrahman Al-Matary, Saud A Alsharif, Ibtihal A Bukhari, Saeed Baradwan, Majed S Alshahrani, Khalid Khadawardi, Ehab Badghish, Bayan Albouq, Afnan Baradwan, Mohammed Abuzaid, Haifa Al-Jundy, Abdullah Alyousef, Wael S Ragab, Ahmed Abu-Zaid
OBJECTIVE:  This study aimed to conduct a systematic review and meta-analysis of all randomized and nonrandomized controlled trials (RCTs and NCTs, respectively) that explored the maternal-neonatal outcomes of cervical osmotic dilators versus dinoprostone in promoting cervical ripening during labor induction. STUDY DESIGN:  Six major databases were screened until August 27, 2022. The quality of included studies was evaluated. The data were summarized as mean difference or risk ratio (RR) with 95% confidence interval (CI) in a random-effects model...
June 19, 2023: American Journal of Perinatology
https://read.qxmd.com/read/37245054/using-dinoprostone-slow-release-vaginal-insert-for-cervical-ripening-in-term-pregnancy-with-oligohydramnios
#36
JOURNAL ARTICLE
To Nhu Thi Ngo Nguyen, Anh Dinh Bao Vuong, Phuc Nhon Nguyen, Ngoc Tran Thi Nguyen, Quang Nhat Ho, Quang Thanh Le
AIMS: The study purposed to evaluate the success rate of cervical ripening using dinoprostone controlled-release vaginal insert and reveal some factors relating to successful cervical ripening. METHODS: This cross-sectional study was conducted at Tu Du Hospital in Vietnam from December 2021 to August 2022. The study enrolled 200 pregnant women with gestational age ≥37 weeks diagnosed with oligohydramnios. These candidates underwent dinoprostone cervical ripening (DCR) according to the local protocol...
May 27, 2023: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/37229912/expediting-labor-induction-in-severe-pre-eclampsia-by-earlier-initiation-of-oxytocin-after-cervical-ripening-a-randomized-study-from-india
#37
JOURNAL ARTICLE
Himani Jangra, Rashmi Bagga, Jasvinder Kalra, Vanita Jain, Subhas Chandra Saha, Praveen Kumar
OBJECTIVE: To observe whether induction of labor (IoL) among women with severe pre-eclampsia (PE) can be expedited by initiating oxytocin early (after 6 h) than after 12 h following cervical ripening with a combined method. METHODS: Women with severe PE and Bishop's < 6 (n = 96) were randomized into two groups. All women received cervical ripening with a combined method (intracervical Foley's plus dinoprostone gel 0.5 mg) following which Group 1 women received oxytocin after 6 h (with Foley's in-situ) and Group 2 after 12 h (after removing Foley's) RESULTS: Majority were nulliparous (63% in group 1 and 77% in group 2) and the mean gestation was similar (35...
May 23, 2023: Pregnancy Hypertension
https://read.qxmd.com/read/37210702/diagnostic-accuracy-of-pre-induction-cervical-elastography-volume-length-and-uterocervical-angle-for-the-prediction-of-successful-induction-of-labor-with-dinoprostone
#38
JOURNAL ARTICLE
Alper İleri, Suna Yıldırım Karaca, Hakan Gölbaşı, Mehmet Adıyeke, Adnan Budak, Mehmet Özer, Hande İleri, Merve Biçer, Ayse Rabia Şenkaya, Sabahattin Anıl Arı, Özge Çeliker Tosun, İbrahim Karaca
PURPOSE: The study's aim is to define among a group of ultrasonographic cervical measurements a candidate parameter predictive of successful of induction of labor in term pregnancies with unfavorable cervix. METHODS: This prospective observational study included 141 pregnant women at term with an unfavorable cervix (Bishop score ≤ 6). All patients underwent clinical and ultrasonographic cervical evaluation before dinoprostone induction. Pre-induction cervical assessments included the Bishop score, cervical length, cervical volume, uterocervical angle, and cervical elastographic parameters...
May 21, 2023: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/37167810/effectiveness-of-dinoprostone-gel-misoprostol-vaginal-insert-and-dinoprostone-vaginal-insert-for-induction-of-labour-in-twin-pregnancies
#39
JOURNAL ARTICLE
J Gent, E Oliver, H Quigley, A Sharp
OBJECTIVES: To compare the effectiveness and safety of Dinoprostone Gel (DG), Misoprostol Vaginal Insert (MVI) and Dinoprostone Vaginal Insert (DVI) for induction of labour (IOL) in twin pregnancies. STUDY DESIGN: Retrospective cohort study of twin pregnancies > 34 + 0 weeks gestation that underwent induction of labour (IOL) with DG, MVI or DVI between December 2016 and November 2019 in a Tertiary NHS hospital, North West England, UK...
July 2023: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/37100837/prediction-of-an-effective-cervical-ripenning-in-the-induction-of-labour-using-vaginal-dinoprostone
#40
JOURNAL ARTICLE
Nuria López Jiménez, Fiamma García Sánchez, Rafael Hernández Pailos, Valentin Rodrigo Álvaro, Ana Pascual Pedreño, María Moreno Cid, Antonio Hernández Martínez, Milagros Molina Alarcón
To develop a predictive model for successful cervical ripening in women that undergo induction of labour by means of a vaginal prostaglandin slow-release delivery system (Propess®).  Prospective observational study on 204 women that required induction of labour between February 2019 and May 2020 at "La Mancha Centro" hospital in Alcázar de San Juan, Spain. The main variable studied was effective cervical ripening (Bishop score > 6). Using multivariate analysis and binary logistic regression, we created three initial predictive models (model A: Bishop Score + Ultrasound cervical length + clinical variables (estimated fetal weight, premature rupture of membranes and body mass index)); model B: Ultrasound cervical lenght + clinical variables; and model C: Bishop score + clinical variables) to predict effective cervical ripening...
April 26, 2023: Scientific Reports
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