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https://www.readbyqxmd.com/read/28227800/a-fresh-perspective-on-dissecting-action-into-discrete-submotions
#1
Justin Horowitz, Yazan Abdel Majeed, James Patton, Justin Horowitz, Yazan Abdel Majeed, James Patton, Justin Horowitz, Yazan Abdel Majeed, James Patton
The hypothesis that reaching motions are constructed from discrete components has been explored since the earliest scientific investigations of human movement, although composition specifics have been contentious. We reinspect this process by analyzing the underlying motor intent (rather than actual motion) using our recently-developed intent determination technique. First, synthetic data analysis was used to determine our accuracy in detecting submotion events. Next, we evaluated this on healthy reaching movements and overcame the problem of indistinguishably blended submotions by exposing subjects to strong, abruptly changing forces, which lead to clear corrections identifiable using direction-based clustering...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226390/single-tunneling-method-with-endoscopic-submucosal-dissection-for-treatment-of-a-rectal-giant-18-cm-laterally-spreading-tumor
#2
Fatih Aslan, Zehra Akpinar, Derya A Yurtlu, Melek Kucuk, Nese Ekinci, Belkis Unsal
No abstract text is available yet for this article.
February 2017: Endoscopy
https://www.readbyqxmd.com/read/28226358/-laparoscopic-segmental-gastrectomy-for-early-gastric-cancer
#3
Lai Xu, Beizhan Niu, Xiyu Sun, Menghua Dai, Yi Xiao
OBJECTIVE: To investigate the feasibility of segmental pylorus-reservation gastrectomy in patients with early gastric cancer. METHOD: A retrospective cohort study on clinical data of 6 patients strictly met the criteria of early gastric cancer locating in the middle of the stomach undergoing laparoscopic segmental gastrectomy from January 2014 to April 2016 at Department of General Surgery, Peking Union Medical College Hospital was carried out. Preoperative clinical staging revealed T1N0M0 for all the cases...
February 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28226357/-analysis-of-clinicopathological-characteristics-and-prognosis-on-42-patients-with-primary-gastric-adenosquamous-cell-carcinoma
#4
Bin Li, Lin Sun, Xiaona Wang, Jingyu Deng, Xuewei Ding, Xuejun Wang, Bin Ke, Li Zhang, Rupeng Zhang, Han Liang
OBJECTIVE: To investigate the clinicopathological characteristics, diagnosis, treatment and prognosis of patients with primary gastric adenosquamous cell carcinoma. METHODS: A total of 5 562 patients with gastric neoplasm were admitted in Tianjin Medical University Cancer Institute and Hospital from January 2001 to January 2011. Among them 42 patients were diagnosed as primary gastric adenosquamous cell carcinoma, accounting for 0.76% of all the patients. The clinicopathological and follow-up data of these 42 patients with primary gastric adenosquamous cell carcinoma were retrospectively analyzed, and Cox proportional hazard model was used to analyze the prognostic factors of gastric adenocarcinoma squamous cell carcinoma...
February 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28226356/-application-of-clockwise-modularized-lymphadenectomy-in-laparoscopic-gastrectomy-for-gastric-cancer
#5
Jiankun Hu, Kun Yang, Xinzu Chen, Weihan Zhang, Kai Liu, Xiaolong Chen, Linyong Zhao, Zongguang Zhou
OBJECTIVE: To investigate the feasibility and efficacy of clockwise modularized lymphadenectomy in laparoscopic gastrectomy for gastric cancer. METHODS: Clinical data of 19 cases who underwent the laparoscopic clockwise modularized lymphadenectomy for gastric cancer (clockwise group) from July 2016 to September 2016 were analyzed retrospectively. The clockwise modularized lymphadenectomy included the fixed operative order, detailed procedure and requirement of lymphadenectomy, which mainly reflected in assisting the exposure of operative field and dissection of lymph nodes through suspending the liver and banding the greater omentum, as well as proposing the requirements and attentions for the dissections of each station of lymph nodes to facilitate the quality control of lymphadenectomy...
February 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28226354/-prognostic-factors-of-lymph-node-negative-metastasis-gastric-cancer
#6
Ding Sun, Huimian Xu, Jinyu Huang
OBJECTIVE: To investigate the prognostic factors of patients with lymph node-negative metastasis gastric cancer (pN0). METHODS: Clinicopathological data of patients with pN0 gastric cancer who underwent radical operation at the Department of Surgical Oncology, The First Hospital of China Medical University from May 1980 to August 2012 were collected and analyzed retrospectively. INCLUSION CRITERIA: (1) Patients were diagnosed as gastric adenocarcinoma; (2) Postoperative pathology confirmed T1a to 4bN0M0 gastric cancer; (3) Total number of harvested lymph node was more than 15...
February 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28226353/-comparison-of-complications-following-open-laparoscopic-and-robotic-gastrectomy
#7
Xin Lan, Hongqing Xi, Kecheng Zhang, Jianxin Cui, Mingsen Li, Lin Chen
OBJECTIVE: To compare clinically relevant postoperative complications after open, laparoscopic, and robotic gastrectomy for gastric cancer. METHODS: Clinical data of patients with gastric cancer who underwent gastrectomy between January 1, 2014 and October 1, 2016 at Chinese People's Liberation Army General Hospital were analyzed retrospectively. All the patients were diagnosed by upper endoscopy and confirmed by biopsy without distant metastasis. They were confirmed with R0 resection by postoperative pathology...
February 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28226350/-value-of-endoscopy-application-in-the-management-of-complications-after-radical-gastrectomy-for-gastric-cancer
#8
Yiqun Zhang, Pinghong Zhou
Endoscopy plays an important role in the diagnosis and treatment of postoperative complications of gastric cancer. Endoscopic intervention can avoid the second operation and has attracted wide attention. Early gastric anastomotic bleeding after gastrectomy is the most common. With the development of technology, emergency endoscopy and endoscopic hemostasis provide a new treatment approach. According to the specific circumstances, endoscopists can choose metal clamp to stop bleeding, electrocoagulation hemostasis, local injection of epinephrine or sclerotherapy agents, and spraying specific hemostatic agents...
February 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28226345/-prevention-of-surgery-related-complications-of-d2-lymphadenectomy-for-gastric-cancer
#9
Han Liang
D2 lymphadenectomy is currently the worldwide standard operation for locally advanced gastric cancer and D2+ is an option for some selected patients. The D2 plus lymphadenectomy includes No.8p, No.10, No.11d, No.12b, No.12p, No.13, No.14v, No.16a2 and No.16b1. Dissection of these groups of lymph nodes may cause related complications. Postoperative complications that can cause prolonged inflammation have significant impact not only on mortality but also on overall survival of patients with gastric cancer even if the tumor is resected curatively...
February 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28226343/-diagnosis-and-risk-assessment-of-postoperative-complications-of-gastric-cancer-in-japan-and-korea
#10
Xiang Hu, Chi Zhang
Radical surgery of gastric cancer (D2 lymph node dissection) as the standard operation is widely used in clinical practice and satisfactory prognosis can be obtained in patients who receive radical gastrectomy. But surgical invasion can cause high morbidity of complications and mortality. The data of large-scale evidence-based medical clinical trials and large databases in Japan and Korea showed that anastomotic leakage, pancreatic leakage and abdominal abscess were the most common complications after gastrectomy, and the morbidity of complication was about 20% and mortality was about 1%...
February 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28226237/novel-insights-into-tree-biology-and-genome-evolution-as-revealed-through-genomics
#11
David B Neale, Pedro J Martínez-García, Amanda R De La Torre, Sara Montanari, Xiao-Xin Wei
Reference genome sequences are the key to the discovery of genes and gene families that determine traits of interest. Recent progress in sequencing technologies has enabled a rapid increase in genome sequencing of tree species, allowing the dissection of complex characters of economic importance, such as fruit and wood quality and resistance to biotic and abiotic stresses. Although the number of reference genome sequences for trees lags behind those for other plant species, it is not too early to gain insight into the unique features that distinguish trees from nontree plants...
February 6, 2017: Annual Review of Plant Biology
https://www.readbyqxmd.com/read/28226233/chemical-genetic-dissection-of-membrane-trafficking
#12
Lorena Norambuena, Ricardo Tejos
The plant endomembrane system is an extensively connected functional unit for exchanging material between compartments. Secretory and endocytic pathways allow dynamic trafficking of proteins, lipids, and other molecules, regulating a myriad of biological processes. Chemical genetics-the use of compounds to perturb biological processes in a fast, tunable, and transient manner-provides elegant tools for investigating this system. Here, we review how chemical genetics has helped to elucidate different aspects of membrane trafficking...
February 13, 2017: Annual Review of Plant Biology
https://www.readbyqxmd.com/read/28225562/the-adipokinetic-hormone-of-mantodea-in-comparison-to-other-dictyoptera
#13
Gerd Gäde, Heather G Marco
Six species of the order Mantodea (praying mantises) are investigated for the presence and sequence of putative adipokinetic hormones (AKHs). The selected species span a wide evolutionary range of various families and subfamilies of the clade Mantodea. The corpora cardiaca of the different species are dissected, methanolic extracts prepared, peptides separated by liquid chromatography, and AKHs detected and sequenced by ion trap mass spectrometry. All six species investigated contain an octapeptide with the primary structure pGlu-Val-Asn-Phe-Thr-Pro-Asn-Trp amide, which is code-named Emppe-AKH and had been found earlier in three other species of Mantodea...
February 22, 2017: Archives of Insect Biochemistry and Physiology
https://www.readbyqxmd.com/read/28225558/cutaneous-adnexal-adenocarcinoma-with-exquisite-sensitivity-to-trastuzumab
#14
Timothy J Brown, David J Sher, Lucien A Nedzi, Randall S Hughes, Muhammad S Beg, Jason Mull, Venetia R Sarode, Saad A Khan
BACKGROUND: Cutaneous adnexal adenocarcinoma is a rare cancer that is occasionally human epidermal growth factor receptor-2 (HER-2)-positive, and demonstrates variable response to HER-2 inhibitors. METHODS: We report a case of adnexal adenocarcinoma of the scalp in a 56-year-old man. He underwent wide local excision with cervical node dissection followed by radiation, but had extensive local recurrence. RESULTS: Pathology demonstrated a poorly differentiated adnexal adenocarcinoma with HER-2 overexpression by immunohistochemistry (IHC) and high HER-2 gene amplification by fluorescence in situ hybridization...
February 22, 2017: Head & Neck
https://www.readbyqxmd.com/read/28225387/successful-treatment-of-spontaneous-coronary-artery-dissection-with-intracoronary-imaging-guidance
#15
Bruno Brochado, André Luz, João Silveira, Henrique C Carvalho, Severo Torres
No abstract text is available yet for this article.
February 20, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28225319/cone-beam-computed-tomography-and-histological-evaluations-of-a-straight-electrode-array-positioning-in-temporal-bones
#16
Isabelle Mosnier, Charlotte Célérier, Jean-Loup Bensimon, Daniele de Seta, Olivier Sterkers, Yann Nguyen, Daniele Bernardeschi
CONCLUSION: CBCT allows a precise evaluation of the dimensions and of the shape of the cochlear duct that is of primary importance for the choice of the length and the design of the electrode array. This radio-histological study confirms that CBCT is a reliable tool to be used in clinical studies to evaluate the position of straight electrode arrays within the cochlear scala. OBJECTIVE: To validate the reliability of cone beam computed tomography (CBCT) in the evaluation of cochlear anatomy and positioning of a straight electrode array, by comparing radiological images to histological analysis of cochlear implanted temporal bones...
March 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28224734/anxiety-genetics-dispatches-from-the-frontier
#17
Jordan W Smoller
Anxiety disorders are the most common class of psychiatric disorders and incur an enormous burden in terms of economic costs, disability and personal suffering. Despite their public health importance and documented heritability, genetic research aimed at identifying the genetic contributions to these disorders has had limited success, particularly in comparison to recent advances in the genetics of other major psychiatric disorders. The major factor contributing to this lagging progress has been a dearth of well-powered genomic studies...
March 2017: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
https://www.readbyqxmd.com/read/28224561/radical-resection-of-a-primary-unresectable-duodenal-cancer-after-chemotherapy-using-s-1-and-cisplatin-report-of-a-case
#18
Masaru Kanehira, Yasuro Futagawa, Kenei Furukawa, Hiroaki Shiba, Tadashi Uwagawa, Katsuhiko Yanaga
BACKGROUND: Therapeutic outcomes and prognosis of primary unresectable duodenal cancer remains unsatisfactory, because effective chemotherapy is not established. CASE PRESENTATION: A 71-year-old male diagnosed with unresectable duodenal carcinoma with distant lymph node metastases was judged inoperable (cT3N2M1 cStage in UICC(7th)). Duodenal obstruction developed due to tumor growth, and the patient underwent laparoscopic gastro-jejunostomy and then combined chemotherapy using S-1 and cisplatin...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28224384/swedish-prospective-multicenter-trial-evaluating-sentinel-lymph-node-biopsy-after-neoadjuvant-systemic-therapy-in-clinically-node-positive-breast-cancer
#19
Linda Holmstrand Zetterlund, Jan Frisell, Athanasios Zouzos, Rimma Axelsson, Thomas Hatschek, Jana de Boniface, Fuat Celebioglu
PURPOSE: Patients with clinically node-positive breast cancer planned for neoadjuvant systemic therapy (NAST) may draw advantages from the nodal downstaging effect and reduce the extent of axillary surgery with sentinel lymph node biopsy (SLNB) performed after NAST. Since there are concerns about lower sentinel lymph node (SLN) detection and higher false-negative rates (FNR) in this setting, our aim was to define the accuracy of SLNB after NAST. METHODS: This Swedish national multicenter trial prospectively recruited 195 breast cancer patients from ten hospitals with T1-T4d biopsy-proven node-positive disease planned for NAST between October 1, 2010 and December 31, 2015...
February 21, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28224278/the-need-of-prophylactic-central-lymph-node-dissection-is-controversial-in-terms-of-postoperative-thyroglobulin-follow-up-of-patients-with-cn0-papillary-thyroid-cancer
#20
Mehmet Hakan Korkmaz, Bülent Öcal, Güleser Saylam, Erman Çakal, Ömer Bayır, Esra Tutal, Emel Çadallı Tatar
PURPOSE: The objective of this study was to investigate whether prophylactic central lymph node dissection (pCLND) facilitates postoperative thyroglobulin (Tg) follow-up in the patients with papillary thyroid carcinoma (PTC). We also questioned whether radioactive iodine (RAI) remnant ablation provides any further advantage in this regard. METHODS: The records of patients with low-intermediate risk PTC who underwent either only total thyroidectomy (TT) or TT in conjunction with pCLND were reviewed...
February 21, 2017: Langenbeck's Archives of Surgery
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