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yellow fever vaccine

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https://www.readbyqxmd.com/read/28529708/yellow-fever-in-the-americas-the-growing-concern-about-new-epidemics
#1
Yeimer Ortiz-Martínez, Andrés Mauricio Patiño-Barbosa, Alfonso J Rodriguez-Morales
Yellow fever (YF) is a haemorrhagic viral disease with a high case fatality rate. It is considered a reemerging infectious disease of remarkable importance. During the last outbreaks in Angola (2015-2016) and Brazil (2016-2017), many cases of YF emerged despite high YF vaccination coverage, increasing the risk of major epidemics in the Americas. Several factors, including the vast border and migratory status of Brazil, the widespread distribution of Aedes mosquitoes and the lack of efficient health policies and surveillance systems, favour this complex epidemiological scenario of reemergence...
2017: F1000Research
https://www.readbyqxmd.com/read/28514646/heparin-removal-by-ecteola-cellulose-pre-treatment-enables-the-use-of-plasma-samples-for-accurate-measurement-of-anti-yellow-fever-virus-neutralizing-antibodies
#2
Ana Carolina Campi-Azevedo, Vanessa Peruhype-Magalhães, Jordana Grazziela Coelho-Dos-Reis, Christiane Costa-Pereira, Anna Yoshida Yamamura, Sheila Maria Barbosa de Lima, Marisol Simões, Fernanda Freire Campos Nunes, Aline de Castro Zacche Tonini, Elenice Moreira Lemos, Ricardo Cristiano Brum, Tatiana Guimarães de Noronha, Marcos da Silva Freire, Maria de Lourdes Sousa Maia, Luiz Antônio Bastos Camacho, Maria Rios, Caren Chancey, Alessandro Romano, Carla Magda Domingues, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho
Technological innovations in vaccinology have recently contributed to bring about novel insights for the vaccine-induced immune response. While the current protocols that use peripheral blood samples may provide abundant data, a range of distinct components of whole blood samples are required and the different anticoagulant systems employed may impair some properties of the biological sample and interfere with functional assays. Although the interference of heparin in functional assays for viral neutralizing antibodies such as the functional plaque-reduction neutralization test (PRNT), considered the gold-standard method to assess and monitor the protective immunity induced by the Yellow fever virus (YFV) vaccine, has been well characterized, the development of pre-analytical treatments is still required for the establishment of optimized protocols...
May 14, 2017: Journal of Immunological Methods
https://www.readbyqxmd.com/read/28506254/reemergence-of-yellow-fever-in-ethiopia-after-50%C3%A2-years-2013-epidemiological-and-entomological-investigations
#3
Abrham Lilay, Negga Asamene, Abyot Bekele, Mesfin Mengesha, Milliyon Wendabeku, Israel Tareke, Abiy Girmay, Yonas Wuletaw, Abate Adossa, Yamar Ba, Amadou Sall, Daddi Jima, Debritu Mengesha
BACKGROUND: Yellow Fever (YF) is a viral hemorrhagic disease transmitted by aedes mosquito species. Approximately, 200,000 cases and 30,000 deaths occur worldwide every year. In Ethiopia, the last outbreak was reported in 1966 with 2200 cases and 450 deaths. A number of cases with deaths from unknown febrile illness reported from South Ari district starting from November 2012. This investigation was conducted to identify the causative agent, source of the outbreak and recommend appropriate interventions...
May 15, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28492447/the-yellow-fever-vaccine-misadventure-of-1942
#4
John S Marr, John T Cathey
In 1942, a hepatitis B outbreak occurred in the US Army after vaccination with contaminated lots of 17D yellow fever vaccine; long-term sequelae were surprisingly limited, and retrospective studies of carrier rates, cirrhosis, and hepatocellular carcinoma were found to be minimal. Later studies identified the contaminant as hepatitis B virus (HBV) in the human serum component of the vaccine. Other than 2 follow-up studies of long-term sequelae and reports within US Military archives, the event has never been fully elucidated in its proper historical context in the medical literature available through MEDLINE (PubMed)...
May 10, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28480154/congenital-tracheobronchomegaly-mounier-kuhn-syndrome-in-a-woman-with-human-immunodeficiency-virus-a-case-report
#5
Amanda Fletcher, Justin Stowell, Socrates Jamoulis
Congenital tracheobronchomegaly (Mounier-Kuhn Syndrome, MKS) is a rare idiopathic disorder characterized by dilation of the central airways, including the trachea and first through fourth order bronchi. MKS disproportionately affects men and results in chronic respiratory tract infections. The diagnosis is made through the synthesis of clinical and radiological data. Here we report a unique case of MKS in a patient with human immunodeficiency virus (HIV) infection. A 45-year-old African American woman with a past medical history of HIV, tobacco and recreational drug abuse, chronic obstructive pulmonary disease, sleep apnea, and a 15-year history of recurrent respiratory infections presented with dyspnea, wheezing, a productive cough, increased yellow-green sputum production, and subjective fevers...
April 4, 2017: Curēus
https://www.readbyqxmd.com/read/28472025/addressing-a-yellow-fever-vaccine-shortage-united-states-2016-2017
#6
Mark D Gershman, Kristina M Angelo, Julian Ritchey, David P Greenberg, Riyadh D Muhammad, Gary Brunette, Martin S Cetron, Mark J Sotir
Recent manufacturing problems resulted in a shortage of the only U.S.-licensed yellow fever vaccine. This shortage is expected to lead to a complete depletion of yellow fever vaccine available for the immunization of U.S. travelers by mid-2017. CDC, the Food and Drug Administration (FDA), and Sanofi Pasteur are collaborating to ensure a continuous yellow fever vaccine supply in the United States. As part of this collaboration, Sanofi Pasteur submitted an expanded access investigational new drug (eIND) application to FDA in September 2016 to allow for the importation and use of an alternative yellow fever vaccine manufactured by Sanofi Pasteur France, with safety and efficacy comparable to the U...
May 5, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28463054/vaccine-vial-stopper-performance-for-fractional-dose-delivery-of-vaccines
#7
Courtney Jarrahian, Daniel Myers, Ben Creelman, Eugene Saxon, Darin Zehrung
Shortages of vaccines such as inactivated poliovirus and yellow fever vaccines have been addressed by administering reduced-or fractional-doses, as recommended by the World Health Organization Strategic Advisory Group of Experts on Immunization, to expand population coverage in countries at risk. We evaluated 3 kinds of vaccine vial stoppers to assess their performance after increased piercing from repeated withdrawal of doses needed when using fractional doses (0.1 mL) from presentations intended for full-dose (0...
May 2, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28437183/first-two-imported-cases-of-zika-virus-infections-in-romania
#8
Simin Aysel Florescu, Ani Ioana Cotar, Corneliu Petru Popescu, Cornelia Svetlana Ceianu, Mihaela Zaharia, Geta Vancea, Daniel Codreanu, Daniela Badescu, Emanoil Ceausu
We report the first two cases of imported Zika virus (ZIKV) infection in Romanian patients returning from areas with ongoing outbreaks and challenges for laboratory diagnostic; first one with a classical pattern of acute flaviviral infection and the second one with an interesting pattern of a secondary flaviviral (ZIKV) infection in a yellow fever-vaccinated child living abroad in an endemic area.
May 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/28434128/aspects-on-the-history-of-transmission-and-favor-of-distribution-of-viruses-by-iatrogenic-action-perhaps-an-example-of-a-paradigm-of-the-worldwide-spread-of-hiv
#9
REVIEW
Lutz G Gürtler, Josef Eberle
Transmission of infectious agents might be associated with iatrogenic actions of charitable help in health care. An example is the vaccination against yellow fever in USA that transmitted hepatitis B virus. Another example is injections of praziquantel for treatment and cure of schistosomiasis in Central and Northern Africa, with a focus in Egypt that has spread hepatitis C virus. There is no indication that human T-lymphotropic virus type 1 was spread by injection treatment for African trypanosomiasis, syphilis and treponematosis, but these treatments might have contributed to the early spread of human immunodeficiency virus type 1 (HIV-1) in Central Africa...
April 22, 2017: Medical Microbiology and Immunology
https://www.readbyqxmd.com/read/28429035/max-theiler-1899-1972-creator-of-the-yellow-fever-vaccine
#10
Siang Yong Tan, Kate Pettigrew
No abstract text is available yet for this article.
April 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28426111/importation-of-yellow-fever-into-china-assessing-travel-patterns
#11
Annelies Wilder-Smith, W Y Leong
Rapid increase in trade and a growing air passenger market encourages high travel volume between the regions associated with increasing risks of such importations including China. Eleven Chinese workers infected during the 2016 yellow fever (YF) outbreak in Angola imported YF into China highlighting the potential for spread into Asia. Using outbound and inbound travel data, we assessed travel patterns from and to YF endemic countries in relation to China. Among YF endemic countries, Angola has the second highest number of travellers into China and also receives the second highest number of Chinese visitors...
July 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28424031/yellow-fever-from-angola-and-congo-a-storm-gathers
#12
Qanta A Ahmed, Ziad A Memish
In common with Zika, Chikungunya and Dengue, Yellow Fever (YF) is an arthropod-borne flavivirus. It is transmitted between humans and from monkeys by mosquitoes of the Aedes aegypti (its principal vector), haemogogus and albopictus varieties. Three cycles of transmission may occur: urban; sylvatic; and intermediate. Recently, sub-Saharan Africa has seen the resurgence of this neglected disease. The current YF outbreak in Angola began in December 2015 in the capital Luanda and by October 2016 there had been > 4300 suspected cases, with 376 deaths (case fatality rate = 8...
April 2017: Tropical Doctor
https://www.readbyqxmd.com/read/28422752/t-bet-b-cells-are-induced-by-human-viral-infections-and-dominate-the-hiv-gp140-response
#13
James J Knox, Marcus Buggert, Lela Kardava, Kelly E Seaton, Michael A Eller, David H Canaday, Merlin L Robb, Mario A Ostrowski, Steven G Deeks, Mark K Slifka, Georgia D Tomaras, Susan Moir, M Anthony Moody, Michael R Betts
Humoral immunity is critical for viral control, but the identity and mechanisms regulating human antiviral B cells are unclear. Here, we characterized human B cells expressing T-bet and analyzed their dynamics during viral infections. T-bet+ B cells demonstrated an activated phenotype, a distinct transcriptional profile, and were enriched for expression of the antiviral immunoglobulin isotypes IgG1 and IgG3. T-bet+ B cells expanded following yellow fever virus and vaccinia virus vaccinations and also during early acute HIV infection...
April 20, 2017: JCI Insight
https://www.readbyqxmd.com/read/28398253/t-cell-mediated-immunity-towards-yellow-fever-virus-and-useful-animal-models
#14
REVIEW
Alan M Watson, William B Klimstra
The 17D line of yellow fever virus vaccines is among the most effective vaccines ever created. The humoral and cellular immunity elicited by 17D has been well characterized in humans. Neutralizing antibodies have long been known to provide protection against challenge with a wild-type virus. However, a well characterized T cell immune response that is robust, long-lived and polyfunctional is also elicited by 17D. It remains unclear whether this arm of immunity is protective following challenge with a wild-type virus...
April 11, 2017: Viruses
https://www.readbyqxmd.com/read/28386132/adaptive-immune-responses-to-booster-vaccination-against-yellow-fever-virus-are-much-reduced-compared-to-those-after-primary-vaccination
#15
Michael Kongsgaard, Maria R Bassi, Michael Rasmussen, Karsten Skjødt, Søren Thybo, Mette Gabriel, Morten Bagge Hansen, Jan Pravsgaard Christensen, Allan Randrup Thomsen, Soren Buus, Anette Stryhn
Outbreaks of Yellow Fever occur regularly in endemic areas of Africa and South America frequently leading to mass vaccination campaigns straining the availability of the attenuated Yellow Fever vaccine, YF-17D. The WHO has recently decided to discontinue regular booster-vaccinations since a single vaccination is deemed to confer life-long immune protection. Here, we have examined humoral (neutralizing antibody) and cellular (CD8 and CD4 T cell) immune responses in primary and booster vaccinees (the latter spanning 8 to 36 years after primary vaccination)...
April 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28380113/prevalence-and-titers-of-yellow-fever-virus-neutralizing-antibodies-in-previously-vaccinated-adults
#16
COMPARATIVE STUDY
Karina Takesaki Miyaji, Vivian Iida Avelino-Silva, Marisol Simões, Marcos da Silva Freire, Carlos Roberto de Medeiros, Patrícia Emilia Braga, Maria Angélica Acalá Neves, Marta Heloisa Lopes, Esper Georges Kallas, Ana Marli Christovam Sartori
Introduction: The World Health Organization (WHO) recommends one single dose of the Yellow Fever (YF) vaccine based on studies of antibody persistency in healthy adults. We assessed the prevalence and titers of YF virus neutralizing antibodies in previously vaccinated persons aged  60 years, in comparison to younger adults. We also evaluated the correlation between antibody titers and the time since vaccination among participants who received one vaccine dose, and the seropositivity among participants vaccinated prior to or within the past 10 years...
April 3, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28366605/yellow-fever-live-attenuated-vaccine-a-very-successful-live-attenuated-vaccine-but-still-we-have-problems-controlling-the-disease
#17
REVIEW
Alan D T Barrett
Yellow fever (YF) is regarded as the original hemorrhagic fever and has been a major public health problem for at least 250years. A very effective live attenuated vaccine, strain 17D, was developed in the 1930s and this has proved critical in the control of the disease. There is little doubt that without the vaccine, YF virus would be considered a biosafety level 4 pathogen. Significantly, YF is currently the only disease where an international vaccination certificate is required under the International Health Regulations...
March 30, 2017: Vaccine
https://www.readbyqxmd.com/read/28358796/yellow-fever-outbreak-kongo-central-province-democratic-republic-of-the-congo-august-2016
#18
John O Otshudiema, Nestor G Ndakala, Elande-Taty K Mawanda, Gaston P Tshapenda, Jacques M Kimfuta, Loupy-Régence N Nsibu, Abdou S Gueye, Jacob Dee, Rossanne M Philen, Coralie Giese, Christopher S Murrill, Ray R Arthur, Benoit I Kebela
On April 23, 2016, the Democratic Republic of the Congo's (DRC's) Ministry of Health declared a yellow fever outbreak. As of May 24, 2016, approximately 90% of suspected yellow fever cases (n = 459) and deaths (45) were reported in a single province, Kongo Central Province, that borders Angola, where a large yellow fever outbreak had begun in December 2015. Two yellow fever mass vaccination campaigns were conducted in Kongo Central Province during May 25-June 7, 2016 and August 17-28, 2016. In June 2016, the DRC Ministry of Health requested assistance from CDC to control the outbreak...
March 31, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28333617/yellow-fever-in-a-traveller-returning-from-suriname-to-the-netherlands-march-2017
#19
Marjan Wouthuyzen-Bakker, Marjolein Knoester, Aad P van den Berg, Corine H GeurtsvanKessel, Marion Pg Koopmans, Coretta Van Leer-Buter, Bob Oude Velthuis, Suzan D Pas, Wilhelmina Lm Ruijs, Jonas Schmidt-Chanasit, Stephen Gs Vreden, Tjip S van der Werf, Chantal Bem Reusken, Wouter Fw Bierman
A Dutch traveller returning from Suriname in early March 2017, presented with fever and severe acute liver injury. Yellow fever was diagnosed by (q)RT-PCR and sequencing. During hospital stay, the patient's condition deteriorated and she developed hepatic encephalopathy requiring transfer to the intensive care. Although yellow fever has not been reported in the last four decades in Suriname, vaccination is recommended by the World Health Organization for visitors to this country.
March 16, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28301446/notes-from-the-field-investigation-of-patients-testing-positive-for-yellow-fever-viral-rna-after-vaccination-during-a-mass-yellow-fever-vaccination-campaign-angola-2016
#20
Andrew T Boyd, Diambi Dombaxe, Rosa Moreira, M S Oliveira, Eusebio Manuel, Carlos Navarro Colorado, Tatiana M Lanzieri
No abstract text is available yet for this article.
March 17, 2017: MMWR. Morbidity and Mortality Weekly Report
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