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yellow fever vaccine

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https://www.readbyqxmd.com/read/29140432/long-term-immune-response-to-yellow-fever-vaccination-in-hiv-infected-individuals-depends-on-hiv-rna-suppression-status-implications-for-vaccination-schedule
#1
Olivia Veit, Cristina Domingo, Matthias Niedrig, Cornelia Staehelin, Beat Sonderegger, Héquet Delphine, Marcel Stoeckle, Alexandra Calmy, Veronique Schiffer, Enos Bernasconi, Domenica Flury, Christoph Hatz, Marcel Zwahlen, Hansjakob Furrer
Background: In HIV-infected individuals the immune response over time to yellow fever vaccination (YFV) and the necessity for booster vaccination are not well understood. Methods: We studied 247 participants of the Swiss HIV Cohort Study (SHCS) with a first YFV after HIV diagnosis and determined their immune responses at one, five, and ten years postvaccination (p.v.) by yellow fever plaque reduction neutralisation titres (PRNT) in stored blood samples. A PRNT of 1:≥10 was regarded as reactive and protective...
November 11, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29133118/functional-characterization-of-a-serine-protease-inhibitor-modulated-in-the-infection-of-the-aedes-aegypti-with-dengue-virus
#2
Tatiane Sanches Soares, Boris Luis Rodriguez Gonzalez, Ricardo José Soares Torquato, Francisco Jose Alves Lemos, André L Costa-da-Silva, Margareth de Lara Capurro Guimarães, Aparecida Sadae Tanaka
During feeding with blood meal, female Aedes aegypti can transmit infectious agents, such as dengue, yellow fever, chikungunya and Zika viruses. Dengue virus causes human mortality in tropical regions of the world, and there is no specific treatment or vaccine with maximum efficiency being used for these infections. In the vector-virus interaction, the production of several molecules is modulated by both mosquitoes and invading agents. However, little information is available about these molecules in the Ae...
November 10, 2017: Biochimie
https://www.readbyqxmd.com/read/29131357/zika-virus-what-we-need-to-know
#3
REVIEW
Farakh Javed, Khanzadi N Manzoor, Mubashar Ali, Irshad U Haq, Abid A Khan, Assad Zaib, Sobia Manzoor
Zika virus is one of the emerging viruses and is of significant threat to human health globally. It is a mosquito borne flavivirus similar to dengue, yellow fever, and West Nile viruses. It was reported about 5 decades ago and then it spreads to different parts of the world. Large outbreaks were reported on Yap Islands in 2007. Now it has gained wide attention globally by health communities. Major vector for virus transmission is Aedes aegypti mosquito. ZIKV infection is mostly asymptomatic but it is also responsible to cause mild influenza like illness to serious manifestations...
November 13, 2017: Journal of Basic Microbiology
https://www.readbyqxmd.com/read/29112671/travel-characteristics-and-pretravel-health-care-among-pregnant-or-breastfeeding-u-s-women-preparing-for-international-travel
#4
Stefan H F Hagmann, Sowmya R Rao, Regina C LaRocque, Stefanie Erskine, Emily S Jentes, Allison T Walker, Elizabeth D Barnett, Lin H Chen, Davidson H Hamer, Edward T Ryan
OBJECTIVE: To study characteristics and preventive interventions of adult pregnant and breastfeeding travelers seeking pretravel health care in the United States. METHODS: This cross-sectional study analyzed data (2009-2014) of pregnant and breastfeeding travelers seen at U.S. travel clinics participating in Global TravEpiNet. Nonpregnant, nonbreastfeeding adult female travelers of childbearing age were used for comparison. We evaluated the prescription of malaria chemoprophylaxis and antibiotics for this population as well as the administration of three travel-related vaccines: hepatitis A, typhoid, and yellow fever...
November 3, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29110131/what-controls-the-acute-viral-infection-following-yellow-fever-vaccination
#5
James Moore, Hasan Ahmed, Jonathan Jia, Rama Akondy, Rafi Ahmed, Rustom Antia
Does target cell depletion, innate immunity, or adaptive immunity play the dominant role in controlling primary acute viral infections? Why do some individuals have higher peak virus titers than others? Answering these questions is a basic problem in immunology and can be particularly difficult in humans due to limited data, heterogeneity in responses in different individuals, and limited ability for experimental manipulation. We address these questions for infections following vaccination with the live attenuated yellow fever virus (YFV-17D) by analyzing viral load data from 80 volunteers...
November 6, 2017: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/29068486/vaccines-and-multiple-sclerosis
#6
REVIEW
J L Frederiksen, M Topsøe Mailand
An association between certain vaccinations and onset or relapse of multiple sclerosis (MS) has been debated. Based on PubMed, we made a thorough literature review and included all relevant studies, 51 on MS and 15 on optic neuritis (ON). Case studies were excluded. With the exception of a live vaccine against yellow fever, vaccinations appear safe in untreated patients with MS and ON. However, most studies were underpowered, and small risks cannot be excluded. One study of BCG vaccination after the first demyelinating event showed even a reduced risk of developing MS...
November 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29037978/expected-immunizations-and-health-protection-for-hajj-and-umrah-2018-an-overview
#7
REVIEW
Jaffar A Al-Tawfiq, Philippe Gautret, Ziad A Memish
BACKGROUND: The annual Hajj and Umrah are one of the largest recurring religious mass gatherings across the globe drawing pilgrims from more than 185 countries. The living circumstances and activities of the pilgrims may create an environment for the occurrence and spread of communicable diseases. Each year, the Health authority of the Kingdom of Saudi Arabia, in coordination with international health authorities, updates health requirements for pilgrims. The Hajj for 2017 took place from August 24 to September 5, 2017...
October 14, 2017: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/29036392/update-from-the-advisory-committee-on-immunization-practices
#8
Sean T O'Leary, David W Kimberlin
The Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts, meets 3 times per year to develop recommendations for vaccine use in the United States. The group has 15 voting members, and each member's term is 4 years. ACIP members and Centers for Disease Control and Prevention (CDC) staff discuss the epidemiology of vaccine-preventable diseases and vaccine research, effectiveness, safety data, and clinical trial results. Representatives from the American Academy of Pediatrics (Carrie L...
September 25, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28986822/global-spread-of-hemorrhagic-fever-viruses-predicting-pandemics
#9
Jean-Paul Gonzalez, Marc Souris, Willy Valdivia-Granda
As successive epidemics have swept the world, the scientific community has quickly learned from them about the emergence and transmission of communicable diseases. Epidemics usually occur when health systems are unprepared. During an unexpected epidemic, health authorities engage in damage control, fear drives action, and the desire to understand the threat is greatest. As humanity recovers, policy-makers seek scientific expertise to improve their "preparedness" to face future events.Global spread of disease is exemplified by the spread of yellow fever from Africa to the Americas, by the spread of dengue fever through transcontinental migration of mosquitos, by the relentless influenza virus pandemics, and, most recently, by the unexpected emergence of Ebola virus, spread by motorbike and long haul carriers...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28983553/vaccination-challenges-in-confronting-the-resurgent-threat-from-yellow-fever
#10
Lin H Chen, Davidson H Hamer
No abstract text is available yet for this article.
November 7, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28978802/early-molecular-correlates-of-adverse-events-following-yellow-fever-vaccination
#11
Candice Yy Chan, Kuan Rong Chan, Camillus Jh Chua, Sharifah Nur Hazirah, Sujoy Ghosh, Eng Eong Ooi, Jenny G Low
The innate immune response shapes the development of adaptive immunity following infections and vaccination. However, it can also induce symptoms such as fever and myalgia, leading to the possibility that the molecular basis of immunogenicity and reactogenicity of vaccination are inseparably linked. To test this possibility, we used the yellow fever live-attenuated vaccine (YFLAV) as a model to study the molecular correlates of reactogenicity or adverse events (AEs). We analyzed the outcome of 68 adults who completed a YFLAV clinical trial, of which 43 (63...
October 5, 2017: JCI Insight
https://www.readbyqxmd.com/read/28975614/t-cell-receptor-alpha-variable-12-2-bias-in-the-immunodominant-response-to-yellow-fever-virus
#12
Amandine Bovay, Vincent Zoete, Garry Dolton, Anna M Bulek, David K Cole, Pierre J Rizkallah, Anna Fuller, Konrad Beck, Olivier Michielin, Daniel E Speiser, Andrew K Sewell, Silvia A Fuertes Marraco
The repertoire of human αβ T cell receptors (TCRs) is generated via somatic recombination of germline gene segments. Despite this enormous variation, certain epitopes can be immunodominant, associated with high frequencies of antigen-specific T cells and/or exhibit bias towards a TCR gene segment. Here, we studied the TCR repertoire of the HLA-A*0201-restricted epitope LLWNGPMAV (hereafter, A2/LLW) from Yellow Fever virus, which generates an immunodominant CD8(+) T cell response to the highly effective YF-17D vaccine...
October 3, 2017: European Journal of Immunology
https://www.readbyqxmd.com/read/28973079/yellow-fever-vaccine-shortages-in-the-united-states-and-abroad-a-critical-issue
#13
Daniel R Lucey, Halsie Donaldson
No abstract text is available yet for this article.
September 26, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28968905/yellow-fever-virus-but-not-zika-or-dengue-virus-inhibits-t-cell-receptor-mediated-t-cell-function-by-an-rna-based-mechanism
#14
James H McLinden, Nirjal Bhattarai, Jack T Stapleton, Qing Chang, Thomas M Kaufman, Suzanne L Cassel, Fayyaz S Sutterwala, Hillel Haim, Jon Houtman, Jinhua Xiang
The Flavivirus genus within the Flaviviridae is comprised of many important human pathogens including Yellow Fever virus (YFV), Dengue virus (DENV) and Zika virus (ZKV), all of which are global public health concerns. Although the related flaviviruses hepatitis C virus and human pegivirus (formerly named GBV-C) interfere with T cell receptor (TCR) signaling by novel RNA and protein based mechanisms, the effect of other flaviviruses on TCR signaling is unknown. Here, we studied the effect of YFV, DENV, and ZKV on TCR signaling...
September 2, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28968794/replication-and-excretion-of-the-live-attenuated-tetravalent-dengue-vaccine-cyd-tdv-in-a-flavivirus-naive-adult-population-assessment-of-vaccine-viremia-and-virus-shedding
#15
Joseph Torresi, Peter C Richmond, Leon G Heron, Ming Qiao, Joanne Marjason, Linda Starr-Spires, Diane van der Vliet, Jing Jin, T Anh Wartel, Alain Bouckenooghe
Background: We assessed replication and excretion of the live attenuated tetravalent dengue vaccine (CYD-TDV) into biological fluids following vaccination in dengue-naive adults in Australia. Methods: Vaccinal viremia/shedding was assessed in a subset of participants enrolled in a lot-to-lot consistency study; 95 participants received 3 subcutaneous doses of CYD-TDV from phase 2/3 lots of the vaccine, and 8 received placebo; doses were administered 6 months apart...
October 17, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28959858/-progress-in-zika-virus-and-its-vaccines
#16
Deqiao Tian, Wei Chen
Like Yellow fever virus, Dengue virus, Japanese encephalitis virus and West Nile virus, Zika virus is also a mosquito-borne flavivirus. Since it was isolated in 1947, there has been little concern over Zika virus due to its limited distribution and mild symptoms. In recent years, especially since 2015, Zika virus has become a global concern because of its outbreak in Brazil and associated microcephaly. Vaccines against Zika virus, regarded as the effective measures to control Zika fever epidemic, are being developed in nearly thirty institutions worldwide...
January 25, 2017: Sheng Wu Gong Cheng Xue Bao, Chinese Journal of Biotechnology
https://www.readbyqxmd.com/read/28958813/chronovac-voyageur-a-study-of-the-immune-response-to-yellow-fever-vaccine-among-infants-previously-immunized-against-measles
#17
Catherine Goujon, Marie-Lise Gougeon, Laura Tondeur, Béatrice Poirier, Valérie Seffer, Philippe Desprès, Paul-Henri Consigny, Muriel Vray
For administration of multiple live attenuated vaccines, the Advisory Committee on Immunization Practices recommends either simultaneous immunization or period of at least 28days between vaccines, due to a possible reduction in the immune response to either vaccine. The main objective of this study was to compare the immune response to measles (alone or combined with mumps and rubella) and yellow fever vaccines among infants aged 6-24months living in a yellow fever non-endemic country who had receivedmeasles and yellow fever vaccines before travelling to a yellow fever endemic area...
October 27, 2017: Vaccine
https://www.readbyqxmd.com/read/28949285/lineage-specific-real-time-rt-pcr-for-yellow-fever-virus-outbreak-surveillance-brazil
#18
Carlo Fischer, Maria C Torres, Pranav Patel, Andres Moreira-Soto, Ernest A Gould, Rémi N Charrel, Xavier de Lamballerie, Rita Maria Ribeiro Nogueira, Patricia C Sequeira, Cintia D S Rodrigues, Beate M Kümmerer, Christian Drosten, Olfert Landt, Ana Maria Bispo de Filippis, Jan Felix Drexler
The current yellow fever outbreak in Brazil prompted widespread yellow fever virus (YFV) vaccination campaigns, imposing a responsibility to distinguish between vaccine- and wild-type YFV-associated disease. We developed novel multiplex real-time reverse transcription PCRs that differentiate between vaccine and American wild-type YFV. We validated these highly specific and sensitive assays in an outbreak setting.
November 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28925936/an-atypical-local-vesicular-reaction-to-the-yellow-fever-vaccine
#19
Robert H Wauters, Camellia L Hernandez, Maureen M Petersen
Yellow fever vaccine is a live attenuated viral inoculation indicated for patients traveling to endemic areas. The vaccine is generally well tolerated with minimal adverse effects. Typical side effects include malaise, pain at the injection site, and, albeit rarely, immediate hypersensitivity reactions. We present a case of a rare adverse reaction to yellow fever vaccine in which a patient developed vesicular lesions resulting in bullae and circumferential hyperpigmentation.
September 19, 2017: Vaccines
https://www.readbyqxmd.com/read/28903515/update-from-the-advisory-committee-on-immunization-practices
#20
Sean T O'Leary, Yvonne A Maldonado, Carrie L Byington
The Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts, meets 3 times per year to develop recommendations for vaccine use in the United States. The group has 15 voting members, and each member's term is 4 years. ACIP members and Centers for Disease Control and Prevention (CDC) staff discuss the epidemiology of vaccine-preventable diseases and vaccine research, effectiveness, safety data, and clinical trial results. Representatives from the American Academy of Pediatrics (C...
September 1, 2017: Journal of the Pediatric Infectious Diseases Society
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