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Koichiro Sato, Sayo Ito, Tomoyuki Kitagawa, Koichi Hirahata, Daisuke Hihara, Kenji Tominaga, Ichiro Yasuda, Iruru Maetani
BACKGROUND: Ultrathin colonoscopes (UTC) reportedly produce less pain during colonoscopy than standard colonoscopes. The aim of this study was to assess the tolerability of an UTC compared with that of a pediatric colonoscope. METHODS: A total of 270 adult patients scheduled to undergo colonoscopy were randomized, with 134 allocated to the UTC group and 136 to the pediatric colonoscope group. Pain was assessed using a visual analog scale. For all procedures, sedation was administered only if requested...
May 9, 2017: Surgical Endoscopy
Laura E Stanley, Angela Lucero, Timothy C Mauntel, Madison Kennedy, Nina Walker, Stephen W Marshall, Darin A Padua, David J Berkoff
PURPOSE: Ultrasound tissue characterization (UTC) is an imaging tool used to quantify tendon structural integrity. UTC has quantified Achilles tendon (AT) acute response to load in athletes; however, AT response to cumulative load over a season is unknown. The purpose of this study was to evaluate AT response across a 4-month competitive season in collegiate cross-country (XC) runners. METHODS: Participants (n=21; male=9, female=12; age=19.8±1.2yrs; height=171...
April 28, 2017: Scandinavian Journal of Medicine & Science in Sports
Dongok Ryu, Sug-Whan Kim, Robert P Breault
In this study, a new global earth system model is introduced for evaluating the optical performance of space instruments. Simultaneous imaging and spectroscopic results are provided using this global earth system model with fully resolved spatial, spectral, and temporal coverage of sub-models of the Earth. The sun sub-model is a Lambertian scattering sphere with a 6-h scale and 295 lines of solar spectral irradiance. The atmospheric sub-model has a 15-layer three-dimensional (3D) ellipsoid structure. The land sub-model uses spectral bidirectional reflectance distribution functions (BRDF) defined by a semi-empirical parametric kernel model...
March 6, 2017: Optics Express
Sumati Gupta, Samantha Greenberg, Jade Grimmett, David Gaston, Neeraj Agarwal, William Lowrance, Joshua Schiffman, Wendy Kohlmann
Interpretation of next-generation sequencing (NGS) of tumor tissue in patients with advanced Urinary Tract Cancer (UTC) is performed to guide treatment selection but may reveal pathogenic variants with germline implications. We identified three patients with UTC with unexpected germline DNA repair gene mutations. Specific testing for these was prompted by the detection of these mutations by tumor NGS. All three patients were nonsmokers with a strong family history of cancer. Two patients had upper tract UTC with age at diagnosis in the 40 s...
March 18, 2017: Familial Cancer
Morgan L Cowan, Dorothy L Rosenthal, Christopher J VandenBussche
BACKGROUND: The Paris System for Reporting Urinary Cytology (TPS) requires 4 cytomorphologic criteria for a definitive diagnosis of high-grade urothelial carcinoma (HGUC) in urinary tract cytology (UTC) specimens: an elevated nuclear-to-cytoplasmic (N/C) ratio (at or above 0.7), markedly atypical nuclear borders, moderate to severe hyperchromasia, and coarse chromatin. However, malignant UTC specimens often contain degenerative changes, and this limits the number of malignant cells meeting all 4 TPS cytomorphologic criteria...
March 8, 2017: Cancer
Hsiu-Wen Tsai, Kevin Fennelly, Karen Wheeler Hegland, Sherry Adams, Jillian A Condrey, Jennifer L Hosford, Paul W Davenport
Elderly white, thin, nonsmoking women appear to be more susceptible to lung infections with Mycobacterium avium complex and other nontuberculous mycobacteria (NTM). It has been postulated that such disease in women is related to the suppression of their cough. We hypothesized that subjects with pulmonary NTM (pNTM) infections may have altered cough physiology compared to unaffected control subjects. We used capsaicin induced cough to assess their cough reflex. Eight white elderly women with stable chronic pNTM lung infections and six unaffected age matched control subjects were recruited...
March 2, 2017: Journal of Applied Physiology
Suvi Sirkku Tuohinen, Tanja Skyttä, Heini Huhtala, Vesa Virtanen, Marko Virtanen, Pirkko-Liisa Kellokumpu-Lehtinen, Pekka Raatikainen
BACKGROUND: Increased cardiovascular morbidity and mortality are major late complications after radiotherapy (RT) in the thoracic region. Ultrasound tissue characterization (UTC) is a noninvasive method for the identification of myocardial changes. The aim of this prospective clinical trial was to assess whether the analysis of cyclic variation of integrated backscatter (CVIBS) can detect early RT-induced myocardial alterations. METHODS: Seventy-three eligible patients with early-stage breast cancer were evaluated before and immediately after adjuvant RT...
February 2017: Echocardiography
J T Zhi, X Q Zheng, M Gao
Thyroid carcinoma (TC) is the most common endocrine cancer and its incidence has been increasing globally over the past decades. With the development of the genetic technology, more and more evidences showed that many genes affect the biological behaviors of TC, making sense to early diagnosis, predicting the prognosis and targeted therapy for TC. BRAF mutation is specific to papillary thyroid carcinoma (PTC). It can not only predict the prognosis, but also have diagnosis value. RET rearrangements are identified as a specific genetic event in PTC...
December 7, 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Chien-Liang Lin, Wen-Tsung Huang, Wen-Chou Fan, Yin-Hsun Feng, Chia-Ho Lin, Chian-Shiung Lin, Chih-Cheng Lu, Tse-Chou Cheng, Chao-Jung Tsao, Sheng-Hsiang Lin
The aim of this study was to investigate cancer risk in patients with a history of urolithiasis and to determine whether intervention for calculi attenuated the risk of subsequent urinary tract cancer (UTC).Using data from the National Health Insurance Research Database in Taiwan, we performed a nationwide cohort study enrolling participants (n = 42,732) aged > 30 years who were diagnosed with urinary tract calculi between 2000 and 2009. Age- and gender-matched insured individuals (n = 213,660) found in the health service records over the same period were recruited as the control group...
December 2016: Medicine (Baltimore)
Ya-Wen Chuang, Mei-Ching Yu, Shih-Ting Huang, Cheng-Kuang Yang, Cheng-Hsu Chen, Ying-Chih Lo, Cheng-Li Lin, Kuo-Hsiung Shu, Tung-Min Yu, Chia-Hung Kao
AIM: This was a nationwide study by National Health Insurance Research Database to investigate the risk of urinary tract cancers (UTCs) for renin-angiotensin-aldosterone system inhibitors including spironolactone. METHODS: A total of 32 167 UTC patients with hypertension were enrolled in the National Health Insurance program between 2005 and 2011. RESULTS: Among different subclasses of renin-angiotensin-aldosterone system inhibitors, the adjusted odds ratio (OR) for UTC risk was 1...
January 2017: Journal of Hypertension
Daiki Nemoto, Kenichi Utano, Shungo Endo, Noriyuki Isohata, David G Hewett, Kazutomo Togashi
BACKGROUND AND AIM: Small-caliber endoscopes such as gastroscopes or pediatric colonoscopes are occasionally required to negotiate fixed or angulated colons. However, the use of a new ultrathin instrument (diameter 7.0 mm) narrower than other conventional colonoscopes has not been evaluated. The aim of the present study was to compare the use compare the use of an ultrathin colonoscope (UTC) with a pediatric colonoscope (PDC) for colonoscopy in older female patients. METHODS: A prospective, randomized, controlled trial was conducted in a single academic endoscopy unit...
November 10, 2016: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
Aijaz Ahmed Sofi, Ali Nawras, Muhammad Ali Khan, Colin W Howden, Wade M Lee
Background and study aims Colonoscopy should reliably intubate the cecum with minimal patient discomfort and without complications. Use of thinner endoscopes to overcome pain during the procedure has shown promise. However, the use of thinner scopes could lead to excess looping and difficulty with therapeutic procedures. The aim of this meta-analysis was to analyze the performance of ultrathin colonoscopes (UTC) and standard colonoscopes for routine colonoscopy. Patients and methods We searched several electronic databases for all randomized controlled trials and nonrandomized (prospective) studies that compared the efficacies of UTC (diameter ≤ 9...
April 2017: Endoscopy
Shi Jia, Xianbin Yu, Hao Hu, Jinlong Yu, Pengyu Guan, Francesco Da Ros, Michael Galili, Toshio Morioka, Leif K Oxenløwe
We propose and experimentally demonstrate THz photonic wireless communication systems with 16-QAM modulation in the 375-450 GHz band. The overall throughput reaches as high as 80 Gbit/s by exploiting four THz channels with 5 Gbaud 16-QAM baseband modulation per channel. We create a coherent optical frequency comb (OFC) for photonic generation of multiple THz carriers based on photo-mixing in a uni-travelling carrier photodiode (UTC-PD). The OFC configuration also allows us to generate reconfigurable THz carriers with low phase noise...
October 17, 2016: Optics Express
Erin Silverman, Christine M Sapienza, Sarah Miller, Giselle Carnaby, Charles Levy, Hsiu-Wen Tsai, Paul W Davenport
Cough and swallow protect the lungs and are frequently impaired following traumatic brain injury (TBI). This project examined cough response to inhaled capsaicin solution challenge in a cohort of four young adults with a history of TBI within the preceding five years. All participants had a history of tracheostomy with subsequent decannulation and dysphagia after their injuries (resolved for all but one participant). Urge to cough (UTC) and cough response were measured and compared to an existing database of normative cough response data obtained from 32 healthy controls (HCs)...
2016: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
Maria-Antonia Serrano, Javier Cañada, Juan Carlos Moreno, Gonzalo Gurrea
Solar ultraviolet (UV) radiation is one of the most important factors in the development of skin cancer in human, solar erythema and skin aging. Nevertheless, numerous studies have shown the benefits of UV solar radiation in moderate doses, such as the reduction of blood pressure and mental health, treatment of various diseases, and the synthesis of vitamin D in the skin. This paper analyses data from solar ultraviolet erythemal (UVER) irradiance in W/m(2) measured in a northern mid-latitude as Valencia (Spain) for the period 2003-2010...
September 21, 2016: Science of the Total Environment
To Setha, Ngan Chantha, Seleena Benjamin, Doung Socheat
A multi-phased study was conducted in Cambodia from 2005-2011 to measure the impact of larviciding with the bacterial larvicide, Bacillus thuringiensis israelensis (Bti), a water dispersible granule (WG) formulation on the vector, Aedes aegypti (L.) and the epidemiology. In our studies, all in-use containers were treated at 8 g/1000 L, including smaller containers and animal feeders which were found to contribute 23% of Ae aegypti pupae. The treated waters were subjected to routine water exchange activities...
September 2016: PLoS Neglected Tropical Diseases
Sajid Pareeth, Nico Salmaso, Rita Adrian, Markus Neteler
Availability of remotely sensed multi-spectral images since the 1980's, which cover three decades of voluminous data could help researchers to study the changing dynamics of bio-physical characteristics of land and water. In this study, we introduce a new methodology to develop homogenised Lake Surface Water Temperature (LSWT) from multiple polar orbiting satellites. Precisely, we developed homogenised 1 km daily LSWT maps covering the last 30 years (1986 to 2015) combining data from 13 satellites. We used a split-window technique to derive LSWT from brightness temperatures and a modified diurnal temperature cycle model to homogenise data which were acquired between 8:00 to 17:00 UTC...
2016: Scientific Reports
Michele Natrella, Chin-Pang Liu, Chris Graham, Frederic van Dijk, Huiyun Liu, Cyril C Renaud, Alwyn J Seeds
We determine the output impedance of uni-travelling carrier (UTC) photodiodes at frequencies up to 400 GHz by performing, for the first time, 3D full-wave modelling of detailed UTC photodiode structures. In addition, we demonstrate the importance of the UTC impedance evaluation, by using it in the prediction of the absolute power radiated by an antenna integrated UTC, over a broad frequency range and confirming the predictions by experimental measurements up to 185 GHz. This is done by means of 3D full-wave modelling and is only possible since the source (UTC) to antenna impedance match is properly taken into account...
May 30, 2016: Optics Express
Ruben Soler, J F Nicolás, S Caballero, E Yubero, J Crespo
From May to September 2012, ozone reductions associated with 15 Saharan dust outbreaks which occurred between May to September 2012 have been evaluated. The campaign was performed at a mountain station located near the eastern coast of the Iberian Peninsula. The study has two main goals: firstly, to analyze the decreasing gradient of ozone concentration during the course of the Saharan episodes. These gradients vary from 0.2 to 0.6 ppb h(-1) with an average value of 0.39 ppb h(-1). The negative correlation between ozone and coarse particles occurs almost simultaneously...
October 2016: Environmental Science and Pollution Research International
E Wezenbeek, N Mahieu, Tm Willems, D Van Tiggelen, M De Muynck, D De Clercq, E Witvrouw
Recently, ultrasound tissue characterization (UTC) was introduced as a reliable method for quantification of tendon structure. Despite increasing publications on the use of UTC, it is striking that there is a lack of normative data in active adolescents. Therefore, the aim of this study was to provide normative values of the Achilles tendon as quantified by UTC. Seventy physiotherapy students (26 male and 44 female students) with no history of Achilles tendon injuries were recruited. The Achilles tendons were scanned with UTC to characterize tendon structure...
July 1, 2016: Scandinavian Journal of Medicine & Science in Sports
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