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https://www.readbyqxmd.com/read/29046918/flow-diverter-treatment-of-cerebral-blister-aneurysms
#1
Russell Cerejo, Mark Bain, Seby John, Julian Hardman, Nina Moore, M Shazam Hussain, Gabor Toth
PURPOSE: Blood blister-like aneurysms (BBA) are small, friable, broad-based aneurysms that represent high risk for rerupture. Treatment of BBA is challenging, and may include surgical wrapping, clipping, multiple overlapping stents, and/or coiling. Flow diversion is a rapidly evolving treatment strategy for intracranial aneurysms, but the evidence for its use in cases of BBA is scarce. METHODS: A retrospective review of flow-diverter-treated, ruptured BBA cases at our tertiary care institution was undertaken...
October 18, 2017: Neuroradiology
https://www.readbyqxmd.com/read/29045414/influence-of-poly-vinylpyrrolidone-concentration-on-properties-of-silver-nanoparticles-manufactured-by-modified-thermal-treatment-method
#2
Leila Gharibshahi, Elias Saion, Elham Gharibshahi, Abdul Halim Shaari, Khamirul Amin Matori
Very narrow and pure silver nanoparticles were synthesized by modified thermal treatment method via oxygen and nitrogen flow in succession. The structural and optical properties of the calcined silver nanoparticles at 600°C with diverse Poly(vinylpyrrolidone) concentrations varied from 2% to 4% were studied by means of different techniques. Fourier transform infrared spectroscopy was used to monitor the production of pure Ag nanoparticles at a given Poly(vinylpyrrolidone) concentration. The X-ray powder diffraction spectra are evidence for the transformation of the amorphous sample at 30°C to the cubic crystalline nanostructures at the calcination temperatures for all Poly(vinylpyrrolidone) concentrations...
2017: PloS One
https://www.readbyqxmd.com/read/29044260/molecular-engineering-of-organic-electroactive-materials-for-redox-flow-batteries
#3
REVIEW
Yu Ding, Changkun Zhang, Leyuan Zhang, Yangen Zhou, Guihua Yu
With high scalability and independent control over energy and power, redox flow batteries (RFBs) stand out as an important large-scale energy storage system. However, the widespread application of conventional RFBs is limited by the uncompetitive performance, as well as the high cost and environmental concerns associated with the use of metal-based redox species. In consideration of advantageous features such as potentially low cost, vast molecular diversity, and highly tailorable properties, organic and organometallic molecules emerge as promising alternative electroactive species for building sustainable RFBs...
October 18, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/29044112/cognitive-task-information-is-transferred-between-brain-regions-via-resting-state-network-topology
#4
Takuya Ito, Kaustubh R Kulkarni, Douglas H Schultz, Ravi D Mill, Richard H Chen, Levi I Solomyak, Michael W Cole
Resting-state network connectivity has been associated with a variety of cognitive abilities, yet it remains unclear how these connectivity properties might contribute to the neurocognitive computations underlying these abilities. We developed a new approach-information transfer mapping-to test the hypothesis that resting-state functional network topology describes the computational mappings between brain regions that carry cognitive task information. Here, we report that the transfer of diverse, task-rule information in distributed brain regions can be predicted based on estimated activity flow through resting-state network connections...
October 18, 2017: Nature Communications
https://www.readbyqxmd.com/read/29043783/marine-mammal-microbiota-yields-novel-antibiotic-with-potent-activity-against-clostridium-difficile
#5
Jessica L Ochoa, Laura M Sanchez, Byoung-Mo Koo, Jennifer S Doherty, Manohary Rajendram, Kerwyn Casey Huang, Carol A Gross, Roger G Linington
The recent explosion of research on the microbiota has highlighted the important interplay between commensal microorganisms and the health of their cognate hosts. Metabolites isolated from commensal bacteria have been demonstrated to possess a range of antimicrobial activities, and it is widely believed that some of these metabolites modulate host behavior, affecting predisposition to disease and pathogen invasion. Our access to the local marine mammal stranding network and previous successes in mining the fish microbiota poised us to test the hypothesis that the marine mammal microbiota is a novel source of commensal bacteria-produced bioactive metabolites...
October 18, 2017: ACS Infectious Diseases
https://www.readbyqxmd.com/read/29043395/measuring-flow-hemodynamic-indices-and-oxygen-consumption-in-children-with-pulmonary-hypertension-a-comparison-of-catheterization-and-phase-contrast-mri
#6
Michal Schäfer, Uyen Truong, Lorna P Browne, Gareth J Morgan, Michael Ross, Richard Ing, Kendall S Hunter, Vitaly O Kheyfets, Steven H Abman, D Dunbar Ivy, Neil Wilson
We sought to compare pulmonary flow hemodynamic indices obtained by Fick and thermodilution catheterization techniques with phase-contrast MRI (PC-MRI) in children with diverse etiologies of pulmonary arterial hypertension (PAH). Calculation of pulmonary flow ([Formula: see text]) using the Fick principle in most catheter laboratories relies on an estimate of oxygen consumption which may limit its reliability. Flow hemodynamic indices acquired from thirty patients with PAH who underwent successful same-day PC-MRI and catheterization were evaluated for absolute and percent bias...
October 17, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29043056/genotype-by-sequencing-identifies-natural-selection-as-a-driver-of-intraspecific-divergence-in-atlantic-populations-of-the-high-dispersal-marine-invertebrate-macoma-petalum
#7
Stacy L Metivier, Jin-Hong Kim, Jason A Addison
Mitochondrial DNA analyses indicate that the Bay of Fundy population of the intertidal tellinid bivalve Macoma petalum is genetically divergent from coastal populations in the Gulf of Maine and Nova Scotia. To further examine the evolutionary forces driving this genetic break, we performed double digest genotype by sequencing (GBS) to survey the nuclear genome for evidence of both neutral and selective processes shaping this pattern. The resulting reads were mapped to a partial transcriptome of its sister species, M...
October 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29043021/genetic-wealth-population-health-major-histocompatibility-complex-variation-in-captive-and-wild-ring-tailed-lemurs-lemur-catta
#8
Kathleen E Grogan, Michelle L Sauther, Frank P Cuozzo, Christine M Drea
Across species, diversity at the major histocompatibility complex (MHC) is critical to individual disease resistance and, hence, to population health; however, MHC diversity can be reduced in small, fragmented, or isolated populations. Given the need for comparative studies of functional genetic diversity, we investigated whether MHC diversity differs between populations which are open, that is experiencing gene flow, versus populations which are closed, that is isolated from other populations. Using the endangered ring-tailed lemur (Lemur catta) as a model, we compared two populations under long-term study: a relatively "open," wild population (n = 180) derived from Bezà Mahafaly Special Reserve, Madagascar (2003-2013) and a "closed," captive population (n = 121) derived from the Duke Lemur Center (DLC, 1980-2013) and from the Indianapolis and Cincinnati Zoos (2012)...
October 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29042328/ruptured-persistent-trigeminal-artery-causing-direct-cavernous-sinus-fistula-treated-with-pipeline-embolization-and-minimal-coiling
#9
Nam K Yoon, Al-Wala Awad, James M Gee, Philipp Taussky
BACKGROUND: Rupture of a persistent trigeminal artery associated with development of a cavernous sinus fistula in a traumatic setting is rare. They are typically treated with coil embolization of the cavernous sinus. CASE DESCRIPTION: We present the case of a 42-year-old woman who developed a direct cavernous carotid fistula after a motor-vehicle accident. Angiographic imaging revealed a rupture point of a persistent trigeminal artery as it connected with the cavernous segment of the internal carotid artery (ICA), causing a cavernous sinus fistula...
October 14, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29040765/flow-diversion-for-the-treatment-of-an-unruptured-paraclinoid-carotid-artery-aneurysm
#10
(no author information available yet)
No abstract text is available yet for this article.
October 11, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29039651/intracellular-drug-uptake-a-comparison-of-single-cell-measurements-using-tof-sims-imaging-and-quantification-from-cell-populations-with-lc-ms-ms
#11
Carla F Newman, Rasmus Havelund, Melissa K Passarelli, Peter S Marshall, Ian Francis, Andrew West, Morgan Russell Alexander, Ian S Gilmore, Colin T Dollery
ToF-SIMS is a label free imaging method that has been shown to enable imaging of amiodarone in single rat macrophage (NR8383) cells. In this study, we show the method extends to three other cell lines relevant to drug discovery: Human embryonic kidney (HEK293), cervical cancer (HeLa) and liver cancer (HepG2). There is significant interest in the variation of drug uptake at the single cell level and we use ToF-SIMS to show that there is great diversity between individual cells and when comparing each of the cell types...
October 17, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29039188/updated-polychlorinated-biphenyl-mass-budget-for-lake-michigan
#12
Jiehong Guo, Kevin Romanak, Stephen Westenbroek, An Li, Russell G Kreis, Ronald A Hites, Marta Venier
This study revisits and updates the Lake Michigan Mass Balance Project (LMMBP) for polychlorinated biphenyls (PCBs) that was conducted in 1994-1995. This work uses recent concentrations of PCBs in tributary and open lake water, air, and sediment to calculate an updated mass budget. Five of the 11 LMMBP tributaries were revisited in 2015. In these five tributaries, the geometric mean concentrations of ∑PCBs (sum of 85 congeners) ranged from 1.52 to 22.4 ng L(-1). The highest concentrations of PCBs were generally found in the Lower Fox River and in the Indiana Harbor and Ship Canal...
October 17, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29036178/substantial-population-structure-of-plasmodium-vivax-in-thailand-facilitates-identification-of-the-sources-of-residual-transmission
#13
Veerayuth Kittichai, Cristian Koepfli, Wang Nguitragool, Jetsumon Sattabongkot, Liwang Cui
BACKGROUND: Plasmodium vivax transmission in Thailand has been substantially reduced over the past 10 years, yet it remains highly endemic along international borders. Understanding the genetic relationship of residual parasite populations can help track the origins of the parasites that are reintroduced into malaria-free regions within the country. METHODOLOGY/RESULTS: A total of 127 P. vivax isolates were genotyped from two western provinces (Tak and Kanchanaburi) and one eastern province (Ubon Ratchathani) of Thailand using 10 microsatellite markers...
October 16, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29035322/analysis-of-genetic-diversity-and-structure-pattern-of-indigofera-pseudotinctoria-in-karst-habitats-of-the-wushan-mountains-using-aflp-markers
#14
Yan Fan, Chenglin Zhang, Wendan Wu, Wei He, Li Zhang, Xiao Ma
Indigofera pseudotinctoria Mats is an agronomically and economically important perennial legume shrub with a high forage yield, protein content and strong adaptability, which is subject to natural habitat fragmentation and serious human disturbance. Until now, our knowledge of the genetic relationships and intraspecific genetic diversity for its wild collections is still poor, especially at small spatial scales. Here amplified fragment length polymorphism (AFLP) technology was employed for analysis of genetic diversity, differentiation, and structure of 364 genotypes of I...
October 16, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29034151/aqueous-shunt-implantation-in-glaucoma
#15
REVIEW
Jing Wang, Keith Barton
Aqueous shunts or glaucoma drainage devices are increasingly utilized in the management of refractory glaucoma. The general design of the most commonly-used shunts is based on the principles of the Molteno implant: ie. a permanent sclerostomy (tube), a predetermined bleb area (plate) and diversion of aqueous humour to the equatorial region and away from the limbal subconjunctival space. These three factors make aqueous shunts more resistant to scarring as compared to trabeculectomy. The two most commonly used shunts are the Ahmed Glaucoma Valve, which contains a flow-restrictor, and the non-valved Baervedlt Glaucoma Implant...
July 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29031500/transcription-and-signaling-regulators-in-developing-neuronal-subtypes-of-mouse-and-human-enteric-nervous-system
#16
Fatima Memic, Viktoria Knoflach, Khomgrit Morarach, Rebecca Sadler, Catia Laranjeira, Jens Hjerling-Leffler, Erik Sundström, Vassilis Pachnis, Ulrika Marklund
BACKGROUND AND AIMS: The enteric nervous system (ENS) regulates gastrointestinal function via different subtypes of neurons, organized into fine-tuned neural circuits. It is not clear how cell diversity is created within the embryonic ENS-information required for development of cell-based therapies and models of enteric neuropathies. We aimed to identify proteins that regulate ENS differentiation and network formation. METHODS: We generated and compared RNA expression profiles of the entire ENS, ENS progenitor cells, and non-ENS gut cells of mice, collected at embryonic days 11...
October 11, 2017: Gastroenterology
https://www.readbyqxmd.com/read/29030832/iron-s-fingerprint-of-deposits-iron-speciation-as-a-geochemical-marker
#17
Przemysław Niedzielski, Lidia Kozak
The article describes the studies of the iron speciation (the occurrence of Fe(II), Fe(III), and complexed iron) in acid leachable fraction of deposits. The speciation of iron was diverse for deposits of different origins and was the specific "fingerprint"-marker of deposition processes. The higher occurrence of Fe(II) may be connected with decantation which has been observed for lake sediments, the majority of Fe(III) with upper flow regime erosion-deposition processes, observed for river sediment deposition during flood episodes...
October 13, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29030621/flow-cytometry-as-a-rapid-analytical-tool-to-determine-physiological-responses-to-changing-o2-and-iron-concentration-by-magnetospirillum-gryphiswaldense-strain-msr-1
#18
Alfred Fernández-Castané, Hong Li, Owen R T Thomas, Tim W Overton
Magnetotactic bacteria (MTB) are a diverse group of bacteria that synthesise magnetosomes, magnetic membrane-bound nanoparticles that have a variety of diagnostic, clinical and biotechnological applications. We present the development of rapid methods using flow cytometry to characterize several aspects of the physiology of the commonly-used MTB Magnetospirillum gryphiswaldense MSR-1. Flow cytometry is an optical technique that rapidly measures characteristics of individual bacteria within a culture, thereby allowing determination of population heterogeneity and also permitting direct analysis of bacteria...
October 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29030499/unexpected-early-radiographic-findings-associated-with-a-ruptured-blister-like-carotid-wall-aneurysm
#19
James West, Jasmeet Singh, Stacey Q Wolfe, Kyle M Fargen
A 33-year-old man presented with aneurysmal subarachnoid hemorrhage from a ruptured, blister-type sidewall internal carotid artery (ICA) aneurysm. Balloon-assisted coiling was performed with residual neck. He subsequently developed severe vasospasm requiring intra-arterial therapies on multiple occasions, during which it was noted that despite widespread vasospasm, a focal segment of the ICA at the site of the aneurysm showed no significant spasm, suggesting underlying vessel abnormality. He was discharged without deficit and scheduled for flow diversion given concern over this potentially pathologic segment of vessel...
October 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29030252/sub-clonal-analysis-of-the-murine-c1498-acute-myeloid-leukaemia-cell-line-reveals-genomic-and-immunogenic-diversity
#20
Virginie Driss, Frédéric Leprêtre, Isabelle Briche, Alexia Mopin, Céline Villenet, Martin Figeac, Bruno Quesnel, Carine Brinster
BACKGROUND: In acute myeloid leukaemia (AML)-affected patients, the presence of heterogeneous sub-clones at diagnosis has been shown to be responsible for minimal residual disease and relapses. The role played by the immune system in this leukaemic sub-clonal hierarchy and maintenance remains unknown. As leukaemic sub-clone immunogenicity could not be evaluated in human AML xenograft models, we assessed the sub-clonal diversity of the murine C1498 AML cell line and the immunogenicity of its sub-clones in immune-competent syngeneic mice...
October 10, 2017: Immunology Letters
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