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Electrostimulation

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https://www.readbyqxmd.com/read/28419879/challenging-the-myth-of-right-non-dominant-hemisphere-lessons-from-cortico-subcortical-stimulation-mapping-in-awake-surgery-and-surgical-implications
#1
REVIEW
Tatiana Vilasboas, Guillaume Herbet, Hugues Duffau
For a long time, the right hemisphere (RH) was considered as "non-dominant", especially in right-handers. In neurosurgical practice, this dogma resulted in the selection of awake procedure with language mapping only for lesions of the left "dominant" hemisphere. Conversely, surgery under general anesthesia (possibly with motor mapping) was usually proposed for right lesions. However, when objective neuropsychological assessments were performed, they frequently revealed cognitive and behavioral deficits following brain surgery, even in the RH...
April 15, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28416459/the-error-of-broca-from-the-traditional-localizationist-concept-to-a-connectomal-anatomy-of-human-brain
#2
REVIEW
Hugues Duffau
Neurology, especially aphasiology, was mainly built on behavioral-structural correlations ("lesion method"). In this setting, Broca's area has been considered as the "speech area"; moreover, this observation led to localizationism. However, advances in brain mapping techniques, as functional neuroimaging and direct electrical stimulation in patients undergoing awake surgery for gliomas, has resulted in a paradigmatic shift regarding models of neural architecture. In fact, the brain is organized in distributed complex networks underpinning sensorimotor, visuospatial, language, cognitive and emotional functions...
April 14, 2017: Journal of Chemical Neuroanatomy
https://www.readbyqxmd.com/read/28397279/change-of-somatosensory-function-of-the-tongue-caused-by-chorda-tympani-nerve-disorder-after-stapes-surgery
#3
Emi Maeda, Hirokazu Katsura, Tomomi Nin, Akiko Sakaguchi-Fukunaga, Yasuo Mishiro, Masafumi Sakagami
OBJECTIVES: Patients after middle ear surgery often complain of taste disturbance and a lingual numbness. The purpose of this study was to objectively assess changes in the somatosensation of the tongue and taste function in patients undergoing stapes surgery. STUDY DESIGN: Prospective study. METHODS: Symptoms of taste disturbance and tongue numbness after surgery were investigated before and after surgery in 41 patients (13 males, 28 females; mean age 41...
April 11, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28334999/rewiring-the-primary-somatosensory-cortex-in-carpal-tunnel-syndrome-with-acupuncture
#4
Yumi Maeda, Hyungjun Kim, Norman Kettner, Jieun Kim, Stephen Cina, Cristina Malatesta, Jessica Gerber, Claire McManus, Rebecca Ong-Sutherland, Pia Mezzacappa, Alexandra Libby, Ishtiaq Mawla, Leslie R Morse, Ted J Kaptchuk, Joseph Audette, Vitaly Napadow
Carpal tunnel syndrome is the most common entrapment neuropathy, affecting the median nerve at the wrist. Acupuncture is a minimally-invasive and conservative therapeutic option, and while rooted in a complex practice ritual, acupuncture overlaps significantly with many conventional peripherally-focused neuromodulatory therapies. However, the neurophysiological mechanisms by which acupuncture impacts accepted subjective/psychological and objective/physiological outcomes are not well understood. Eligible patients (n = 80, 65 female, age: 49...
April 1, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28262048/wireless-electrostimulation-a-new-approach-in-combating-infection
#5
Manousos E Kambouris, Antonios Markogiannakis, Michael Arabatzis, Yiannis Manoussopoulos, Maria Kantzanou, Aristea Velegraki
Electrostimulation (ES), hitherto successfully employed in wound treatment, has shown potential in antimicrobial applications, suggesting its use as synergistic to or replacement of antibiotics. The differential susceptibility of pathogens and host tissue and organs to various ES modalities might allow selective use against specific infections. The use of ES is cheaper in terms of development/testing, routine application and environmental footprint. If extensive substitution of chemical compounds is achieved, the development of resistance might be reversed through negative selection...
March 2017: Future Microbiology
https://www.readbyqxmd.com/read/28255448/effects-of-different-early-rehabilitation-techniques-on-haemodynamic-and-metabolic-parameters-in-sedated-patients-protocol-for-a-randomised-single-bind-cross-over-trial
#6
Clément Medrinal, Yann Combret, Guillaume Prieur, Aurora Robledo Quesada, Tristan Bonnevie, Francis Edouard Gravier, Éric Frenoy, Olivier Contal, Bouchra Lamia
INTRODUCTION: Early rehabilitation has become widespread practice for patients in intensive care; however, the prevalence of intensive care unit-acquired weakness remains high and the majority of physiotherapy is carried out in bed. Several inbed rehabilitation methods exist, but we hypothesise that techniques that provoke muscle contractions are more effective than passive techniques. METHODS: A randomised, controlled cross-over study will be carried out to evaluate and compare the effectiveness of early rehabilitation techniques on cardiac output (CO) in sedated patients in intensive care...
2017: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/28248019/-using-autonomous-electrostimulation-device-erektron-in-treating-female-overactive-bladder
#7
G Yu Yarin, O V Shelyakina, V N Fedorenko, A V Alekseeva, I A Vilgelmi
INTRODUCTION: Overactive bladder (OAB) is one of the most common syndromes of lower urinary tract dysfunction. Besides standard therapy using anticholinergic medications, comprehensive management of overactive bladder includes physiotherapy. AIM: To test the clinical effectiveness and safety of autonomous electrostimulation device "Erektron" in treating OAB in women. MATERIALS AND METHODS: The study was conducted at the Urology and Gynecology Clinic of the Innovative Medical Technology Center between 25...
November 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28209965/high-amplitude-electrical-stimulation-can-reduce-elicited-neuronal-activity-in-visual-prosthesis
#8
Alejandro Barriga-Rivera, Tianruo Guo, Chih-Yu Yang, Amr Al Abed, Socrates Dokos, Nigel H Lovell, John W Morley, Gregg J Suaning
Retinal electrostimulation is promising a successful therapy to restore functional vision. However, a narrow stimulating current range exists between retinal neuron excitation and inhibition which may lead to misperformance of visual prostheses. As the conveyance of representation of complex visual scenes may require neighbouring electrodes to be activated simultaneously, electric field summation may contribute to reach this inhibitory threshold. This study used three approaches to assess the implications of relatively high stimulating conditions in visual prostheses: (1) in vivo, using a suprachoroidal prosthesis implanted in a feline model, (2) in vitro through electrostimulation of murine retinal preparations, and (3) in silico by computing the response of a population of retinal ganglion cells...
February 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28207903/correction-reversing-age-related-changes-of-the-laryngeal-muscles-by-chronic-electrostimulation-of-the-recurrent-laryngeal-nerve
#9
Michael Karbiener, Jonathan C Jarvis, Justin D Perkins, Hermann Lanmüller, Martin Schmoll, Hanna S Rode, Claus Gerstenberger, Markus Gugatschka
[This corrects the article DOI: 10.1371/journal.pone.0167367.].
2017: PloS One
https://www.readbyqxmd.com/read/28162255/direct-electrical-bipolar-electrostimulation-for-functional-cortical-and-subcortical-cerebral-mapping-in-awake-craniotomy-practical-considerations
#10
J Pallud, O Rigaux-Viode, R Corns, J Muto, C Lopez Lopez, C Mellerio, X Sauvageon, E Dezamis
INTRODUCTION: The aim of brain glioma surgery is to maximize the quality of resection, while minimizing the risk of sequelae. Due to the frequent location of gliomas near or within eloquent areas, owing to their infiltrative feature, and because of major interindividual variability, the anatomofunctional organization and connectivity must be studied individually. Therefore, to optimize the benefit-to-risk ratio of surgery, intraoperative functional mapping is extensively used. MATERIAL AND METHODS: This article aims at describing the rationale, indications and practical aspects of intraoperative direct electrical bipolar electrostimulation for cortical and subcortical mapping under awake conditions using the asleep-awake asleep anaesthetic protocol in the setting of cerebral gliomas...
February 2, 2017: Neuro-Chirurgie
https://www.readbyqxmd.com/read/28161012/intraoperative-identification-of-the-negative-motor-network-during-awake-surgery-to-prevent-deficit-following-brain-resection-in-premotor-regions
#11
F Rech, H Duffau, C Pinelli, A Masson, P Roublot, A Billy-Jacques, H Brissart, T Civit
INTRODUCTION: Surgical resection in premotor areas can lead to supplementary motor area syndrome as well as a permanent deficit. However, recent findings suggest a putative role of the negative motor network in those dysfunctions. Our objective was to compare the functional results in two groups of adult patients who underwent the resection of a frontal glioma with and without resection of the negative motor networks. MATERIAL AND METHODS: Twelve patients (total of 13 surgeries) were selected for awake surgery for a frontal glioma...
February 1, 2017: Neuro-Chirurgie
https://www.readbyqxmd.com/read/28155848/optimal-voltage-stimulation-parameters-for-network-mediated-responses-in-wild-type-and-rd10-mouse-retinal-ganglion-cells
#12
Archana Jalligampala, Sudarshan Sekhar, Eberhart Zrenner, Daniel L Rathbun
To further improve the quality of visual percepts elicited by microelectronic retinal prosthetics, substantial efforts have been made to understand how retinal neurons respond to electrical stimulation. It is generally assumed that a sufficiently strong stimulus will recruit most retinal neurons. However, recent evidence has shown that the responses of some retinal neurons decrease with excessively strong stimuli (a non-monotonic response function). Therefore, it is necessary to identify stimuli that can be used to activate the majority of retinal neurons even when such non-monotonic cells are part of the neuronal population...
April 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28103290/involvement-of-ddah-adma-nos-cgmp-and-cox-2-ptgis-camp-pathways-in-human-tissue-kallikrein-1-protecting-erectile-function-in-aged-rats
#13
Kai Cui, Yang Luan, Zhe Tang, Ke Rao, Tao Wang, Zhong Chen, Shaogang Wang, Jihong Liu, Daowen Wang
Our previous studies had reported that Human Tissue Kallikrein 1 (hKLK1) preserved erectile function in aged transgenic rats, while the detailed mechanism of hKLK1 protecting erectile function in aged rats through activation of cGMP and cAMP was not mentioned. To explore the latent mechanism, male wild-type Sprague-Dawley rats (WTR) and transgenic rats harboring the hKLK1 gene (TGR) were fed to 4 and 18 months old and divided into four groups: young WTR (yWTR) as the control, aged WTR (aWTR), aged TGR (aTGR) and aged TGRs with HOE140 (aTGRH)...
2017: PloS One
https://www.readbyqxmd.com/read/27995271/-functional-electrostimulation-for-drop-foot-treatment-clinical-outcome
#14
D Yao, E Jakubowitz, S Ettinger, L Claassen, C Plaass, C Stukenborg-Colsman, K Daniilidis
INTRODUCTION: Neurologic paralysis of the foot due to damage to the central nervous system is primarily caused by a cerebral insult. The ankle-foot orthosis (AFO), which is the classical conservative treatment option, is associated with drawbacks, e.g., increased contractures, limited mobilization from the sitting position, and cosmetic aspects. METHODS: Functional external electrostimulation (FES) is an suitable treatment method for patients with a central lesion and intact peroneal nerve...
December 19, 2016: Der Orthopäde
https://www.readbyqxmd.com/read/27941686/venom-gland-transcriptomic-and-proteomic-analyses-of-the-enigmatic-scorpion-superstitionia-donensis-scorpiones-superstitioniidae-with-insights-on-the-evolution-of-its-venom-components
#15
Carlos E Santibáñez-López, Jimena I Cid-Uribe, Cesar V F Batista, Ernesto Ortiz, Lourival D Possani
Venom gland transcriptomic and proteomic analyses have improved our knowledge on the diversity of the heterogeneous components present in scorpion venoms. However, most of these studies have focused on species from the family Buthidae. To gain insights into the molecular diversity of the venom components of scorpions belonging to the family Superstitioniidae, one of the neglected scorpion families, we performed a transcriptomic and proteomic analyses for the species Superstitionia donensis. The total mRNA extracted from the venom glands of two specimens was subjected to massive sequencing by the Illumina protocol, and a total of 219,073 transcripts were generated...
December 9, 2016: Toxins
https://www.readbyqxmd.com/read/27928210/effects-of-a-whole-body-electrostimulation-program-on-strength-sprinting-jumping-and-kicking-capacity-in-elite-soccer-players
#16
Andre Filipovic, Marijke Grau, Heinz Kleinöder, Philipp Zimmer, Wildor Hollmann, Wilhelm Bloch
The aim of the present study was to investigate the effect of a 14-week dynamic Whole-Body Electrostimulation (WB-EMS) training program on muscular strength, soccer relevant sprint, jump and kicking velocity performance in elite soccer players during competitive season. Twenty-two field-players were assigned to 2 groups: WB-EMS group (EG, n = 12), jump-training group (TG, n = 10). The training programs were conducted twice a week concurrent to 6-7 soccer training sessions during the 2nd half of the season. Participants were tested before (baseline), during (wk-7) and after (wk-14)...
December 2016: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/27926631/effect-of-pectoral-electrostimulation-on-reduction-of-mammary-ptosis-after-bariatric-surgery
#17
RANDOMIZED CONTROLLED TRIAL
Jaime Ruiz-Tovar, Carolina Llavero
BACKGROUND: Over 90% of women report to be very dissatisfied with the aspect of their breast after bariatric surgery. Breast reconstructive surgeries are often not funded by the National Health Service or private health insurances in many countries and the patient must pay a high economic amount to undergo it. PATIENTS AND METHODS: A prospective randomized clinical trial of patients undergoing bariatric surgery was performed. Patients were randomly assigned into 3 groups: patients undergoing percutaneous electrostimulation of the pectoral muscle combined with specific training (group 1), patients doing the specific training alone (group 2), and patients without any specific treatment (group 3)...
December 2016: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/27906050/the-sh3-and-cysteine-rich-domain-3-stac3-gene-is-important-to-growth-fiber-composition-and-calcium-release-from-the-sarcoplasmic-reticulum-in-postnatal-skeletal-muscle
#18
Xiaofei Cong, Jonathan Doering, Davi A G Mazala, Eva R Chin, Robert W Grange, Honglin Jiang
BACKGROUND: The SH3 and cysteine-rich domain 3 (Stac3) gene is specifically expressed in the skeletal muscle. Stac3 knockout mice die perinatally. In this study, we determined the potential role of Stac3 in postnatal skeletal muscle growth, fiber composition, and contraction by generating conditional Stac3 knockout mice. METHODS: We disrupted the Stac3 gene in 4-week-old male mice using the Flp-FRT and tamoxifen-inducible Cre-loxP systems. RESULTS: RT-qPCR and western blotting analyses of the limb muscles of target mice indicated that nearly all Stac3 mRNA and more than 70 % of STAC3 protein were deleted 4 weeks after tamoxifen injection...
April 11, 2016: Skeletal Muscle
https://www.readbyqxmd.com/read/27893858/reversing-age-related-changes-of-the-laryngeal-muscles-by-chronic-electrostimulation-of-the-recurrent-laryngeal-nerve
#19
Michael Karbiener, Jonathan C Jarvis, Justin D Perkins, Hermann Lanmüller, Martin Schmoll, Hanna S Rode, Claus Gerstenberger, Markus Gugatschka
Age related atrophy of the laryngeal muscles -mainly the thyroarytenoid muscle (TAM)- leads to a glottal gap and consequently to a hoarse and dysphonic voice that significantly affects quality of life. The aim of our study was to reverse this atrophy by inducing muscular hypertrophy by unilateral functional electrical stimulation (FES) of the recurrent laryngeal nerve (RLN) in a large animal model using aged sheep (n = 5). Suitable stimulation parameters were determined by fatiguing experiments of the thyroarytenoid muscle in an acute trial...
2016: PloS One
https://www.readbyqxmd.com/read/27889602/toxicity-evaluation-and-initial-characterization-of-the-venom-of-a-colombian-latrodectus-sp
#20
Alexandra Rueda, Emilio Realpe, Alfredo Uribe
The genus Latrodectus has not been studied in Colombia even though it is medically important worldwide; there are three species for the country, this study focused on a non-identified species found in the Tatacoa Desert in the Huila Department. This research is the first approximation to the extraction, composition analysis and toxicity evaluation of the venom of a species of the genus Latrodectus in Colombia; and aims to evaluate the toxicity by the initial characterization of its venom. The venom extraction was accomplished with electrostimulation and total protein concentration was determined by the Lowry method and BCA assays from crude venom; with these methods, high protein concentration of the samples was measured...
January 2017: Toxicon: Official Journal of the International Society on Toxinology
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