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https://www.readbyqxmd.com/read/28731930/early-life-exposure-to-chinese-famine-modifies-the-association-between-hypertension-and-cardiovascular-disease
#1
Zumin Shi, Stephen J Nicholls, Anne W Taylor, Dianna J Magliano, Sarah Appleton, Paul Zimmet
OBJECTIVE: Studies have shown that famine exposure during early life may increase the risk of cardiovascular disease (CVD), hypertension, and diabetes during adulthood. We aimed to assess whether exposure to the Chinese famine (1959-1961) modifies the association between hypertension and CVD. METHODS: We investigated data of 5772 adults born between 1954 and 1964 from the China Health and Retirement Longitudinal Study. CVD was based on self-reported doctor's diagnosis of heart problems (heart attack, coronary heart disease, angina, congestive heart failure, or other heart problems) and stroke...
July 20, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28659214/the-risk-of-stroke-after-prenatal-exposure-to-famine
#2
J Horenblas, S R de Rooij, T J Roseboom
Prenatal exposure to famine is associated with an increased risk of metabolic and cardiovascular diseases in the offspring at adult age. The aim of this study was to assess whether prenatal exposure to undernutrition increases the risk of stroke. This study was performed in the Dutch famine birth cohort, which consist of 2414 members who were born between 1943 and 1947 in the Netherlands. In a subsample of 1177 individuals, interviews were conducted using standardized questionnaires to obtain information about medical history (which included specific questions regarding stroke) and lifestyle...
June 29, 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/28610568/fetal-and-infant-exposure-to-severe-chinese-famine-increases-the-risk-of-adult-dyslipidemia-results-from-the-china-health-and-retirement-longitudinal-study
#3
Zhenghe Wang, Changwei Li, Zhongping Yang, Jun Ma, Zhiyong Zou
BACKGROUND: To explore the associations between the Chinese famine exposure in early life and the dyslipidemia in adulthood. METHODS: We selected 2752 participants from the baseline survey of China Health and Retirement Longitudinal Study (CHARLS) 2011-2012 to evaluate the associations of early life the Chinese famine exposure with risk of dyslipidemia in adulthood. Dyslipidemia was defined as TC (Total Cholesterol): HDL-C (High-Density Lipoprotein Cholesterol) ratio ≥ 5...
June 14, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28586274/famine-exposure-during-early-life-and-risk-of-hypertension-in-adulthood-a-meta-analysis
#4
Xueling Xin, Jie Yao, Feng Yang, Dongfeng Zhang
Background Many epidemiologic studies have explored the association between famine exposure and the risk of hypertension, but the results remain controversial. Objective A meta-analysis was performed to determine the association between early life famine exposure, fetal famine exposure, and childhood famine exposure and risk of hypertension. Methods A literature search was performed in PubMed, Web of science, Embase and China National Knowledge Infrastructure for relevant articles published up to October 2016...
June 6, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28576899/association-between-exposure-to-the-chinese-famine-during-infancy-and-the-risk-of-self-reported-chronic-lung-diseases-in-adulthood-a-cross-sectional-study
#5
Zhenghe Wang, Zhiyong Zou, Zhongping Yang, Yanhui Dong, Jun Ma
OBJECTIVE: To examine the association between early-life exposure to the Chinese famine and the risk of chronic lung diseases in adulthood. DESIGN: Data analysis from a cross-sectional survey. SETTING AND PARTICIPANTS: 4135 subjects were enrolled into the study from the China Health and Retirement Longitudinal Study (CHARLS) 2011-2012 baseline survey to analyse the associations between prenatal and early postnatal famine exposure and the risk of chronic lung diseases in adulthood...
June 2, 2017: BMJ Open
https://www.readbyqxmd.com/read/28526850/drought-and-child-mortality-a-meta-analysis-of-small-scale-surveys-from-ethiopia
#6
Tefera Darge Delbiso, Chiara Altare, Jose Manuel Rodriguez-Llanes, Shannon Doocy, Debarati Guha-Sapir
Despite the intuitive connection between drought and mortality, we still lack a sound quantitative synthesis of evidence drawn from the available data. In this study, we estimate the pooled under-five death rates (U5DR) and assess the effect of drought on child death in Ethiopia. Small-scale mortality surveys were searched from the Complex Emergency Database and then aggregated spatially and temporally with drought exposure data from the Global Drought Monitor and food insecurity data from the Famine Early Warning Systems Network...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28521622/exodus-from-hunger-the-long-term-health-consequences-of-the-1959-1961-chinese-famine
#7
Zhuoni Zhang, Shige Song, Xiaogang Wu
This article examines the long-term health consequences of China's 1959-1961 famine by comparing people who stayed in Guangdong and endured the famine with people who crossed the border to immigrate to Hong Kong and thus escaped the famine. Based on data from the Hong Kong Panel Study of Social Dynamics (HKPSSD) and the China Family Panel Studies (CFPS), we focused on two health indicators-body mass index (BMI) and self-rated health (SRH)-of the cohort born before 1959. Our results show that the stayers who experienced the famine have a lower BMI than the emigrants, and they are likely to have a poor SRH...
2017: Biodemography and Social Biology
https://www.readbyqxmd.com/read/28499082/exacerbation-of-liver-steatosis-following-exposure-to-famine-and-overnutrition
#8
Zhiyuan Ning, Kun Zhang, Li Zhao, You Lu, Honglin Sun, Chi Chen, Xiaomin Nie, Meng Lu, Ningjian Wang, Yingli Lu
SCOPE: People suffering from famine in early life and overnutrition in adulthood may have an increased risk for liver steatosis. We aimed to investigate the effects and mechanisms of early nutrition restriction and overnutrition on de novo lipogenesis in the liver. METHODS AND RESULTS: Three-wk-old male rats were food restricted for 4 wk and refed a high-fat or normal fat diet individually in metabolic cages for 9 wk. Weight-matched groups were also set up. Fatty acid synthetase expression was measured to estimate de novo lipogenesis in the liver...
May 12, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28498832/prenatal-exposure-to-the-great-chinese-famine-and-mid-age-hypertension
#9
Lei Wu, Xueqin Feng, Axin He, Yi Ding, Xiuwen Zhou, Zhice Xu
BACKGROUND: One of the most terrible famines last century was Great Chinese Famine (GCF) in 1959~1961 when millions of people died from starving. Under-nutrition during famine between the Western and Eastern (Dutch Hungry vs. GCF) was similar, while cardiovascular consequences might not be the same. Addressing such questions may gain new insight into prevention of cardiovascular diseases. METHODS: A retrospective cohort of 18,593 participants aged 43-49 years of old, was from Suzhou, China...
2017: PloS One
https://www.readbyqxmd.com/read/28443508/nutritional-deficiency-in-early-life-facilitates-aging-associated-cognitive-decline
#10
Yu Kang, Yun Zhang, Zijuan Feng, Mingjing Liu, Yanhua Li, Huan Yang, Dan Wang, Lingling Zheng, Dandan Lou, Liangping Cheng, Chunjiang Chen, Weitao Zhou, Yi Feng, Xiaoyong Li, Jianzhong Duan, Mengjiao Yu, Shou Yang, Yuhang Liu, Xin Wang, Bo Deng, Chenghui Liu, Xiuqing Yao, Chi Zhu, Chunrong Liang, Xiaolong Zeng, Sisi Ren, Qunying Li, Yin Zhong, Yong Zhang, Jun Kang, Yong Yan, Huaqing Meng, Zhaohui Zhong, Weihui Zhou, Yanjiang Wang, Tingyu Li, Weihong Song
BACKGROUND: Nutrition is important for the fetal developmental programming. Nutritional deficiency in early life could increase the susceptibility to many aging-related disorders including cognitive decline. OBJECTIVE: Our study aims to investigate the effect of early famine exposure on aging-associated cognitive function. METHODS: We recruited 6790 subjects born between 1956 to 1964 during which the Great Chinese Famine occurred (1959-1961)...
April 24, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/28353598/increase-in-the-prevalence-of-arthritis-in-adulthood-among-adults-exposed-to-chinese-famine-of-1959-to-1961-during-childhood-a-cross-sectional-survey
#11
Xianglong Xu, Lingli Liu, Wenxi Xie, Yong Zhang, Huan Zeng, Fan Zhang, Cesar Reis, Xianqing Cao, Yong Zhao
The developmental origins hypothesis postulates that under-nutrition in the early stage of life is associated with an increased risk of disease in adulthood. This study aimed to examine the association of exposure to the Chinese famine of 1959 to 1961 in early life with the risk of arthritis in adulthood.From July to September 2009, the study adopted multistage stratified random sampling cross-sectional survey to recruit 1224 eligible adults in Chongqing. Famine exposure groups were categorized into 3 groups: (1) childhood exposure, (2) fetal exposure, and (3) nonexposure...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28338900/exposure-to-the-chinese-famine-of-1959-61-in-early-life-and-long-term-health-conditions-a-systematic-review-and-meta-analysis
#12
Chihua Li, L H Lumey
Background: Most Chinese people over 55 years old today have experienced the Great Leap Forward Famine of 1959-61. Many reports suggested that the famine could have profound long-term health effects for exposed birth cohorts. A systematic review and meta-analysis was carried out to summarize reported famine effects on long-term health. Methods: Relevant reports were identified by searching PubMed, Embase, Chinese Wanfang Data and Chinese National Knowledge Infrastructure databases...
August 1, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28291790/anaemia-among-children-in-a-drought-affected-community-in-south-central-ethiopia
#13
RANDOMIZED CONTROLLED TRIAL
Taye Gari, Eskindir Loha, Wakgari Deressa, Tarekegn Solomon, Hanibale Atsbeha, Meselech Assegid, Alemayehu Hailu, Bernt Lindtjørn
INTRODUCTION: As part of a field trial (PACTR201411000882128) to provide evidence on the combined use of long-lasting insecticidal nets and indoor residual spray for malaria prevention, we measured haemoglobin values among children aged 6 to 59 months. The aim of this study was to estimate the prevalence of anaemia, and to determine the risk factors of anaemia and change in haemoglobin value in Adami Tullu district in south-central Ethiopia. METHODS: Repeated cross-sectional surveys among 2984 children in 2014 and 3128 children in 2015; and a cohort study (malaria as exposure and anaemia as outcome variable) were conducted...
2017: PloS One
https://www.readbyqxmd.com/read/28280003/epigenetic-memory-in-response-to-environmental-stressors
#14
Paolo Vineis, Aristotelis Chatziioannou, Vincent T Cunliffe, James M Flanagan, Mark Hanson, Micheline Kirsch-Volders, Soterios Kyrtopoulos
Exposure to environmental stressors, toxicants, and nutrient deficiencies can affect DNA in several ways. Some exposures cause damage and alter the structure of DNA, but there is increasing evidence that the same or other environmental exposures, including those that occur during fetal development in utero, can cause epigenetic effects that modulate DNA function and gene expression. Some epigenetic changes to DNA that affect gene transcription are at least partially reversible (i.e., they can be enzymatically reversed after cessation of exposure to environmental agents), but some epigenetic modifications seem to persist, even for decades...
June 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28273874/early-life-nutritional-programming-of-type-2-diabetes-experimental-and-quasi-experimental-evidence
#15
REVIEW
Alexander M Vaiserman
Consistent evidence from both experimental and human studies suggest that inadequate nutrition in early life can contribute to risk of developing metabolic disorders including type 2 diabetes (T2D) in adult life. In human populations, most findings supporting a causative relationship between early-life malnutrition and subsequent risk of T2D were obtained from quasi-experimental studies ('natural experiments'). Prenatal and/or early postnatal exposures to famine were demonstrated to be associated with higher risk of T2D in many cohorts around the world...
March 5, 2017: Nutrients
https://www.readbyqxmd.com/read/28241183/association-of-gestational-weight-gain-and-maternal-body-mass-index-in-early-pregnancy-with-risk-for-nonaffective-psychosis-in-offspring
#16
Euan Mackay, Christina Dalman, Håkan Karlsson, Renee M Gardner
Importance: Prenatal exposure to famine is associated with a 2-fold risk for nonaffective psychoses. Less is known about whether maternal nutrition states during pregnancy modify offspring risk for nonaffective psychoses in offspring in well-fed populations. Objective: To determine whether gestational weight gain (GWG) during pregnancy and maternal body mass index (BMI) in early pregnancy are associated with risk for nonaffective psychoses in offspring. Design, Setting and Participants: This population-based cohort study used data from Swedish health and population registers to follow up 526 042 individuals born from January 1, 1982, through December 31, 1989, from 13 years of age until December 31, 2011...
April 1, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28076319/impact-of-nutrition-on-pollutant-toxicity-an-update-with-new-insights-into-epigenetic-regulation
#17
REVIEW
Jessie B Hoffman, Michael C Petriello, Bernhard Hennig
Exposure to environmental pollutants is a global health problem and is associated with the development of many chronic diseases, including cardiovascular disease, diabetes and metabolic syndrome. There is a growing body of evidence that nutrition can both positively and negatively modulate the toxic effects of pollutant exposure. Diets high in proinflammatory fats, such as linoleic acid, can exacerbate pollutant toxicity, whereas diets rich in bioactive and anti-inflammatory food components, including omega-3 fatty acids and polyphenols, can attenuate toxicant-associated inflammation...
March 1, 2017: Reviews on Environmental Health
https://www.readbyqxmd.com/read/28057132/-association-between-famine-exposure-during-early-life-and-bmi-in-adulthood
#18
R R Meng, J H Si, J Lyu, Y Guo, Z Bian, C Q Yu, H Y Zhou, Y L Tan, P Pei, J S Chen, Z M Chen, L M Li
Objective: To examine the influence of famine exposure during early life on BMI in adulthood. Methods: A total of 94 052 participants recruited in the baseline survey of China Kadoorie Biobank were included in this study. The participants who were born between October 1956 and September 1958, between October 1959 and September 1961 and between October 1962 and September 1964 were classified as group born before famine, group born during famine and group born after famine (control group). The regression coefficients and 95% confidence intervals (CIs) for BMI of famine exposure groups were estimated by linear regression model...
November 10, 2016: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28051192/global-warming-and-its-health-impact
#19
Antonella Rossati
Since the mid-19th century, human activities have increased greenhouse gases such as carbon dioxide, methane, and nitrous oxide in the Earth's atmosphere that resulted in increased average temperature. The effects of rising temperature include soil degradation, loss of productivity of agricultural land, desertification, loss of biodiversity, degradation of ecosystems, reduced fresh-water resources, acidification of the oceans, and the disruption and depletion of stratospheric ozone. All these have an impact on human health, causing non-communicable diseases such as injuries during natural disasters, malnutrition during famine, and increased mortality during heat waves due to complications in chronically ill patients...
January 2017: International Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27999932/association-of-famine-exposure-during-early-life-with-the-risk-of-type-2-diabetes-in-adulthood-a-meta-analysis
#20
Li Liu, Weijing Wang, Jianping Sun, Zengchang Pang
PURPOSE: The association between famine exposure (defined as lengthy and continuous deprivation of food) during early life and type 2 diabetes (T2DM) in adulthood remains controversial. A meta-analysis was performed to better clarify the relation of famine exposure to later T2DM risk. METHODS: A systematic literature search was performed in PubMed, Web of Science, Embase and China National Knowledge Infrastructure for relevant available articles. The articles were limited to those in English or Chinese from January 1990 to June 2016...
December 20, 2016: European Journal of Nutrition
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