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Mitral regurgitation

Muhammad Ali Chaudhry, Allen Johnson, James Thomas Heywood
OBJECTIVES: Stiff left atrial syndrome is an intriguing clinical phenomena characterized by reduced left atrial compliance, pulmonary venous hypertension and exacerbations of volume overload. We conducted a retrospective review of patients diagnosed with stiff left atrial syndrome at our center. METHODS: All patients admitted to our hospital with volume overload and pulmonary venous hypertension who were diagnosed with stiff left atrial syndrome based on evidence by echocardiogram and right heart catheterization between July 2011 and July 2013 were included in this retrospective review...
September 16, 2018: Current Hypertension Reviews
Frank E Corrigan, John H Chen, Aneel Maini, John C Lisko, Lucia Alvarez, Norihiko Kamioka, Shawn Reginauld, Patrick T Gleason, Jose F Condado, Jane Wenjing Wei, Jose N Binongo, Patricia Keegan, Sharon Howell, Vinod H Thourani, Peter C Block, Stephen D Clements, Vasilis C Babaliaros, Stamatios Lerakis
OBJECTIVES: In this study, the authors hypothesized that intraprocedural improvement of pulmonary venous (PV) waveforms are predictive of improved outcomes. In this report, they analyzed intraprocedural invasive and echocardiographic changes with respect to rehospitalization and mortality. BACKGROUND: The effects of hemodynamic changes during percutaneous mitral valve repair (PMVR) with MitraClip (Abbott Vascular, Santa Clara, California) are incompletely characterized...
September 6, 2018: JACC. Cardiovascular Imaging
Po-Chao Hsu, Wen-Hsien Lee, Chun-Yuan Chu, Wei-Chung Tsai, Hung-Hao Lee, Chee-Siong Lee, Hsueh-Wei Yen, Tsung-Hsien Lin, Wen-Chol Voon, Wen-Ter Lai, Sheng-Hsiung Sheu, Ho-Ming Su
BACKGROUND: Tricuspid regurgitation pressure gradient (TRPG) is reportedly a predictor of cardiovascular (CV) mortality in patients without atrial fibrillation (AF); its relationship with cardiac outcomes in patients with AF has never been evaluated. This study aimed to examine the ability of TRPG to predict CV events and all-cause mortality in patients with AF. MATERIALS AND METHODS: Comprehensive echocardiography was performed in 155 patients with persistent AF...
August 2018: American Journal of the Medical Sciences
Jia Rui Kwan, Keith Sheng Hng Low, Rahul Lohan, Vishal G Shelat
Percutaneous transhepatic biliary drainage (PTBD) is safe treatment for biliary decompression given certain indications. However, this is temporary until definitive drainage is established. We report on a 76-year-old lady with recurrent pyogenic cholangitis and PTBD catheter fracture. She had hepatitis B virus-related Child-Pugh class A liver cirrhosis, hypothyroidism, hyperlipidaemia, and previous atrial fibrillation with a background of mild mitral, tricuspid and aortic valvular regurgitation. She had history of laparoscopic cholecystectomy in the past...
August 2018: Annals of Hepato-Biliary-Pancreatic Surgery
Sulafa Ali, Heitham Awadallah, Ahmed Al Hamim, Hussam Al Hussein, Mohamed Al Amin Al Sunni, Tajudeen Bushari, Mohamed H Ahmed
Background: Rheumatic heart disease (RHD) is prevalent in Sudan's rural areas including Gezira state in central Sudan. We initiated a control program aiming at measurement of the echocardiographic (echo) prevalence of RHD, training of health workers and public awareness. Methods: This is a cross-sectional and interventional study conducted in Gezira State, Al Managil Locality from Nov 2016 to February 2018. We used handheld echo (HHE) to detect the prevalence of RHD in school children and those tested positives were referred for standard echo...
August 2018: Cardiovascular Diagnosis and Therapy
Amgad Mentias, Alaa Alashi, Peyman Naji, A Marc Gillinov, L Leonardo Rodriguez, Tomislav Mihaljevic, Rakesh M Suri, Richard A Grimm, Lars G Svensson, Brian P Griffin, Milind Y Desai
Background: Despite preserved left ventricular ejection fraction (LVEF), patients with significant primary mitral regurgitation (MR) often have reduced exercise capacity. In asymptomatic patients with ≥3+ primary MR undergoing rest-stress echocardiography (RSE), we sought to evaluate the incremental impact of left ventricular global longitudinal strain (LV-GLS) on exercise capacity. Methods: A total of 660 asymptomatic patients with ≥3+ primary MR, non-dilated LV and LVEF ≥60% (mean age, 57±14 years, 66% men, body mass index or BMI 25±4 kg/m2 ) who underwent RSE at our center between 2001 and 2013 were included...
August 2018: Cardiovascular Diagnosis and Therapy
Farshad Tahmasebi, Alice Hurrell, Amie Ford, Manish Gupta, Damien Geindreau, Dominic Pimenta, Constantinos O'Mahony
Spontaneous coronary artery dissection is a rare but important cause of acute coronary syndrome. Its relevance for women during the puerperium mandates awareness and understanding amongst obstetric healthcare professionals. The aetiology of the increased risk in pregnancy has not been fully elucidated, but include medial eosinophilic angitis, pregnancy-induced degeneration of collagen in conjunction with the stresses of parturition, and rupture of the vasa vasorum. The risk of mortality necessitates prompt diagnosis, usually by angiography...
September 2018: Obstetric Medicine
Rachid Abou, Melissa Leung, Laurien Goedemans, Georgette E Hoogslag, Martin J Schalij, Nina Ajmone Marsan, Jeroen J Bax, Victoria Delgado
Little is known about the proportion of ST-segment elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention, who have reduced left ventricular ejection fraction (LVEF) within 48 hours (baseline) of admission and exhibit LVEF recovery under optimal guideline-based medical treatment. Therefore, the present study evaluates the evolution of LVEF in patients after STEMI and under guideline-based medical therapy. In 2,853 STEMI patients treated with primary percutaneous coronary intervention, echocardiography was performed at baseline and at 6 months follow-up...
August 20, 2018: American Journal of Cardiology
Xiaodong Sun, Wei Qiu, Yuguo Chen, Guoyue Lv, Zhongqi Fan
RATIONALE: Severe cardiac dysfunction or severe pulmonary hypertension is a contraindication of liver transplantation (LT). Extracorporeal membrane oxygenation (ECMO) is an advanced therapy for severe lung and/or cardiocirculatory dysfunction or failure. The application of ECMO to patients during the LT perioperative period may help recipients with severe cardiac disease to maintain the heart function and alleviate the reperfusion syndrome. PATIENT CONCERNS: A female liver recipient complained about weakness for 6 months...
September 2018: Medicine (Baltimore)
Adrian Kłapyta, Jerzy Pregowski, Zbigniew Chmielak, Piotr Szymański, Jarosław Skowroński, Patrycjusz Stokłowa, Krzysztof Kukuła, Mariusz Kłopotowski, Paweł Tyczyński, Paweł Jelski, Łukasz Kalińczuk, Kacper Milczanowski, Adam Witkowski
No abstract text is available yet for this article.
September 13, 2018: Kardiologia Polska
Ching-Wei Lee, Shih-Hsien Sung, Wei-Ming Huang, Chiao-Po Hsu, Kuo-Piao Chung
No abstract text is available yet for this article.
September 11, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
Roberta De Rosa, Angelo Silverio, Cesare Baldi, Marco Di Maio, Costantina Prota, Ilaria Radano, Julia Rey, Eva Herrmann, Rodolfo Citro, Federico Piscione, Gennaro Galasso
BACKGROUND: The aim of this study was to investigate long-term survival, clinical status, and echocardiographic findings of patients with severe functional mitral regurgitation (FMR) undergoing MitraClip (MC) treatment and to explore the role of baseline features on outcome. Methods and Results: Randomized and observational studies of FMR patients undergoing MC treatment were collected to evaluate the overall survival, New York Heart Association (NYHA) class and echocardiographic changes after MC treatment...
September 13, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
Christopher S G Murray, Ahmed Y Salama, Raziye E Akdogan, Serge Harb, Tamanna Nahar, Navin C Nanda
Moderate-to-severe tricuspid regurgitation affects approximately 1.6 million people in the United States. An estimated 8000 patients will undergo tricuspid surgery annually, leaving a large number of patients with this condition untreated. Many of these individuals who are not referred for surgery engender a large unmet clinical need; this may be primarily due to the surgical risk involved. In persons who are categorized as high-risk surgical candidates, percutaneous procedures present a viable alternative...
September 2018: Echocardiography
Marvin H Eng, Dee Dee Wang
PURPOSE OF REVIEW: This report aims to define the clinical and anatomic variables key in determining patient suitability for transcatheter mitral valve therapies. RECENT FINDINGS: Candidacy for transcatheter mitral valve repair requires weighing the clinical variables that may impact the ability to improve patient symptoms and prolong survival that include left ventricular ejection fraction, symptom severity, pulmonary hypertension, and magnitude of residual regurgitation or stenosis...
September 12, 2018: Current Cardiology Reports
Hatem Mowafy, Scott Lilly, David A Orsinelli, Gregory Rushing, Juan Crestanello, Konstantinos Dean Boudoulas
BACKGROUND:  Floppy mitral valve/mitral valve prolapse (FMV/MVP), a heritable disorder of connective tissue, often leads to mitral regurgitation (MR) and is the most common cause for mitral valve surgery in developed countries. Connective tissue disorders may affect aortic function, and a stiff aorta may increase the severity of MR. Aortic function, however, has not been studied in FMV/MVP with MR. METHODS:  A total of 17 patients (11 men, 6 women) with FMV/MVP and significant MR were compared with 20 controls matched for age and gender...
September 12, 2018: Aorta (Stamford, Conn.)
Julia Pohl, Peter Luedike, Rolf Alexander Jánosi, Tienush Rassaf
MitraClip® implantation is commonly used in patients with severe mitral regurgitation (MR) and who are at high risk for surgical mitral valve repair. The occurrence of stroke or transient ischemic attack is a potential complication in patients undergoing MitraClip implantation, and incidences of up to 2.6% have been reported. Herein is reported the case of an 84-year-old woman with severe MR and a thin filamentous structure at the rim of the left atrial appendage of unknown etiology. Due to a high surgical risk, the heart team decided to perform endovascular mitral valve repair using the MitraClip procedure...
November 2017: Journal of Heart Valve Disease
Masashi Takeshita, Hirokuni Arai, Tomohiro Mizuno, Keiji Oi, Masahumi Yashima
BACKGROUND: True parachute mitral valve and parachute-like asymmetric mitral valve are associated with congenital anomalies of the papillary muscles, which involves an abnormal anatomy of the papillary muscles and chordae. METHODS: Two patients are described with mitral valve regurgitation and papillary muscle anomalies. Mitral valve repair using artificial chordae reconstruction and ring annuloplasty was attempted in both cases. RESULTS: The first patient had a true parachute mitral valve, while the second patient had a parachute-like asymmetric mitral valve...
November 2017: Journal of Heart Valve Disease
Inês Rodrigues, Luísa Branco, Lino Patrício, Luís Bernardes, João Abreu, Duarte Cacela, Ana Galrinho, Rui Ferreira
BACKGROUND: Percutaneous balloon mitral valvuloplasty (PMV) is the cornerstone of rheumatic mitral stenosis treatment in suitable patients. Previous studies have reported low rates of technical failure and few major complications, with good long-term results after successful PMV. The study aim was to assess the very long-term outcome in patients after PMV performed at a single tertiary center. METHODS: Between 1991 and 2010, a total of 213 consecutive patients underwent PMV at the authors' center...
November 2017: Journal of Heart Valve Disease
Tomás Benito-González, Rodrigo Estévez-Loureiro, Ignacio Iglesias-Gárriz, Javier Gualis, Armando Pérez de Prado, Carmen Garrote, Martin J Swaans, Jan A S Van der Heyden, Ted Feldman, Cristina Giannini, David Alonso, Miguel Rodriguez-Santamarta, Mario Castaño, Felipe Fernández-Vázquez
BACKGROUND: The MitraClip® system is a percutaneous treatment for mitral regurgitation (MR) that has shown promising results in patients who are inoperable or at high risk for mitral surgery. Data on the efficacy of the system over optimal medical therapy, above all in patients with functional MR, are scarce. The study aim was to assess the effect of MitraClip on the survival of patients with moderate/severe or severe MR compared to medical therapy, using meta-analytical techniques. METHODS: Independently, reviewers searched electronically for relevant articles based on predefined criteria and end-points...
November 2017: Journal of Heart Valve Disease
Prakash Chand Negi, Kunal Mahajan, Vivek Rana, Sachin Sondhi, Nitin Mahajan, Sanjay Rathour, Ritesh Verma, Ashish Dhiman, Munish Dev, Shivani Rao, Sanjeev Asotra, Rajeev Bhardwaj, Neeraj Ganju, Arvind Kandoria, Rajeev Merwaha, Rajesh Sharma, Nirmal Kolte, Ravi Kumar V, Prince Kumar Paul, Davinder Pal Singh
BACKGROUND: Despite the high prevalence of rheumatic heart disease (RHD) in developing countries such as India, data on characteristics, complications, and treatment practices are lacking. The HP-RHD (Himachal Pradesh Rheumatic Heart Disease) registry aimed at reporting these parameters in patients with RHD from a northern state of India. METHODS: A total of 2,005 consecutive patients of RHD were enrolled over a period of 6 years (2011 to 2016) in the present study...
September 6, 2018: Global Heart
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