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Mitral regurgitation

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https://www.readbyqxmd.com/read/29457259/prosthetic-mitral-valve-thrombosis-malfunction-and-paroxysmal-mitral-regurgitation
#1
Nagaraja Moorthy, Rajiv Ananthakrishna, Dattatreya P V Rao, Satvic C Manjunath, Manjunath C Nanjappa
Intermittent dysfunction of mechanical mitral valve prosthesis is an uncommon condition. It carries serious clinical implications if unrecognized. Here, we present a case of a 28-year-old female with a history of rheumatic multivalvular disease, for which she had undergone double valve replacement and tricuspid annuloplasty. Six months later, she presented with heart failure. Clinical examination revealed intermittent loss of closing clicks followed by a pansystolic murmur at the apex, suggestive of mitral prosthetic valve dysfunction...
February 19, 2018: Echocardiography
https://www.readbyqxmd.com/read/29455830/transaortic-alfieri-edge-to-edge-repair-for-functional-mitral-regurgitation
#2
Ken-Ichi Imasaka, Eiki Tayama, Shigeki Morita, Ryohei Toriya, Yukihiro Tomita
There is controversy about handling functional mitral regurgitation in patients undergoing aortic valve or proximal aortic operations. We describe a transaortic Alfieri edge-to-edge repair for functional mitral regurgitation that reduces operative excessive invasion and prolonged cardiopulmonary bypass time. Between May 2013 and December 2016, 10 patients underwent transaortic Alfieri edge-to-edge mitral repair. There were no operative deaths. The severity of mitral regurgitation immediately after the operation by transesophageal echocardiography was none or trivial in all patients...
March 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29455818/mitral-regurgitation-exacerbation-due-to-sutureless-aortic-valve-replacement
#3
Timothy Lee, Alexander J C Mittnacht, Shinobu Itagaki, Allan Stewart
Sutureless aortic valves are increasingly used for aortic valve replacement (AVR) with excellent outcomes. Implantation requires device expansion in a subannular position within the native aortic root. We report a patient with severe aortic stenosis who received a Perceval sutureless AVR (LivaNova, London, United Kingdom), resulting in a competent prosthesis with an absence of paravalvular leak and aortic regurgitation. However, this implantation resulted in the exacerbation of mitral regurgitation. The sutureless valve required explantation, and a traditional sutured valve was subsequently implanted, which returned the mitral regurgitation to baseline...
March 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29453001/transmitral-septal-myectomy-for-hypertrophic-obstructive-cardiomyopathy
#4
Brody Wehman, Mehrdad Ghoreishi, Nathaniel Foster, Libin Wang, Michael N D'Ambra, Nathan Maassel, Sam Maghami, Rachael Quinn, Murtaza Dawood, Stacy Fisher, James S Gammie
BACKGROUND: Intrinsic abnormalities of the mitral valve are common in patients with hypertrophic cardiomyopathy and may need to be addressed at operation. METHODS: Consecutive patients undergoing transmitral septal myectomy were retrospectively reviewed. The ventricular septum was exposed through a left atriotomy, and the anterior leaflet of the mitral valve was detached from its annulus. An extended myectomy was performed to the base of the papillary muscles. After myectomy, the anterior leaflet was reattached and concomitant mitral valve repair or replacement was performed...
February 13, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29449413/hemodynamics-in-primary-mitral-regurgitation-support-for-and-challenges-to-the-conventional-wisdom
#5
EDITORIAL
Linda D Gillam, Leo Marcoff
No abstract text is available yet for this article.
February 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29449412/hemodynamic-characteristics-in-significant-symptomatic-and-asymptomatic-primary-mitral-valve-regurgitation-at-rest-and-during-exercise
#6
Rine Bakkestrøm, Ann Banke, Nicolaj L Christensen, Redi Pecini, Akhmadjon Irmukhamedov, Mads Andersen, Barry A Borlaug, Jacob E Møller
BACKGROUND: In severe asymptomatic primary mitral valve regurgitation without risk factors, surgery strategy is controversial. We sought to clarify whether being symptomatic corresponds to the hemodynamic burden and reduced exercise capacity. A better understanding of this may contribute to optimize timing of surgery. METHODS AND RESULTS: Subjects with asymptomatic (New York Heart Association functional class I, n=29) or symptomatic (New York Heart Association functional class II and III, n=28) significant primary mitral valve regurgitation (effective regurgitant orifice, ≥0...
February 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29444321/left-ventricular-regional-dyssynchrony-predicts-improvements-in-moderate-ischaemic-mitral-regurgitation-after-off-pump-coronary-artery-bypass
#7
Xiaotian Sun, Guoqian Huang, Jiechun Huang, Meng Shi, Fangrui Wang, Liewen Pang, Yiqing Wang
OBJECTIVES: The aim of this study was to explore the predictors of the improvement in moderate ischaemic mitral regurgitation (IMR) after off-pump coronary artery bypass grafting (OPCAB) focusing on left ventricular (LV) dyssynchrony. METHODS: A prospective study was performed among 135 patients (age at surgery, mean ± SD: 67.0 ± 8.2 years, 33.3% women) with prior myocardial infarction and moderate IMR undergoing OPCAB from 2008 to 2015. Preoperative and follow-up clinical and echocardiographic parameters were analysed, focusing on LV global/regional dyssynchrony...
February 12, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29444226/benfluorex-induced-severe-primary-tricuspid-and-mitral-regurgitation-requiring-a-double-valve-replacement
#8
Marc Eugène, Patrick Bruneval, Nicolas Bonnet, David Attias
No abstract text is available yet for this article.
February 12, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29443354/assessment-of-myocardial-fibrosis-by-late-gadolinium-enhancement-imaging-and-biomarkers-of-collagen-metabolism-in-chronic-rheumatic-mitral-regurgitation
#9
Ruchika Meel, Richard Nethononda, Elena Libhaber, Therese Dix-Peek, Ferande Peters, Mohammed Essop
BACKGROUND: In chronic rheumatic mitral regurgitation (CRMR), involvement of the myocardium in the rheumatic process has been controversial. Therefore, we sought to study the presence of fibrosis using late gadolinium enhancement cardiac magnetic resonance imaging (LGE-CMR) and biomarkers of collagen turnover in CRMR. METHODS: Twenty-two patients with CRMR underwent CMR and echocardiography. Serum concentrations of matrix metalloproteinase- 1 (MMP-1), tissue inhibitor of MMP-1 (TIMP- 1), MMP-1-to-TIMP-1 ratio, procollagen III N-terminal pro-peptide (PIIINP) and procollagen type IC peptide (PIP) were measured...
February 6, 2018: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/29442998/acute-kidney-injury-following-percutaneous-edge-to-edge-vs-minimally-invasive-surgical-mitral-valve-repair-incidence-predictors-and-prognostic-value
#10
Maria Isabel Körber, Maximilian Scherner, Kathrin Kuhr, Hugai Kasisada, Svenja Ney, Roman Pfister, Parwis Rahmanian, Jens Wippermann, Thorsten Wahlers, Stephan Baldus, Volker Rudolph
AIMS: This study sought to determine the incidence and identify predictors of acute kidney injury (AKI) following percutaneous edge-to-edge mitral valve repair (PMVR) and compare the risk of AKI between PMVR and surgical mitral valve repair (SMVR). METHODS AND RESULTS: We performed a single-centre analysis of 378 patients receiving treatment for mitral regurgitation (196 consecutive patients undergoing PMVR and 182 patients undergoing SMVR). The incidence of AKI (any stage according to KDIGO) following PMVR was 17...
October 10, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29442340/aortic-valve-replacement-using-autologous-pericardium-single-centre-experience-with-the-ozaki-technique
#11
Oliver Reuthebuch, Luca Koechlin, Ulrich Schurr, Martin Grapow, Jens Fassl, Friedrich S Eckstein
OBJECTIVE: To assess the clinical implementation and report preliminary results of a novel technique called the Ozaki procedure for stentless aortic valve replacement through reconstruction of the valve leaflets from autologous pericardium. METHOD: Between September 2015 and May 2017 30 patients (20 males, mean ± standard deviation age 66.83 ± 10.55 years) suffering from aortic stenosis (AS, n = 7), aortic regurgitation (AR, n = 12), or a combination of both (AS/AR, n = 11) were assigned for an Ozaki procedure...
February 14, 2018: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29437886/secondary-mitral-regurgitation-part-2-deliberations-on-mitral-surgery-and-transcatheter-repair
#12
REVIEW
William H Gaasch, Theo E Meyer
Secondary mitral regurgitation (MR) develops as a consequence of postinfarction remodelling of the ventricle or other causes of left ventricular (LV) dilatation and dysfunction. The presence of MR amplifies the poor prognosis of the failing ventricle, but it has not been established whether the adverse outcomes stem from the MR or whether the MR is simply a marker of progressive LV dysfunction. In this article, an attempt will be made to clarify the clinical impact of mitral surgery and transcatheter repair in patients with secondary MR...
February 2, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29436196/predictors-of-long-term-outcomes-of-percutaneous-mitral-valvuloplasty-in-patients-with-rheumatic-mitral-stenosis
#13
Darae Kim, Hyemoon Chung, Jong Ho Nam, Dong Hyuk Park, Chi Young Shim, Jung Sun Kim, Hyuk Jae Chang, Geu Ru Hong, Jong Won Ha
PURPOSE: We determined factors associated with long-term outcomes of patients who underwent successful percutaneous mitral balloon valvuloplasty (PMV). MATERIALS AND METHODS: Between August 1980 and May 2013, 1187 patients underwent PMV at Severance Hospital, Seoul, Korea. A total of 742 patients who underwent regular clinic visits for more than 10 years were retrospectively analyzed. The endpoints consisted of repeated PMV, mitral valve (MV) surgery, and cardiovascular-related death...
March 2018: Yonsei Medical Journal
https://www.readbyqxmd.com/read/29432364/per-ventricular-insertion-of-melody-valve-in-valve-in-the-neoaortic-position-in-a-single-ventricle-patient
#14
Nicholas S Clarke, Howaida El-Said, John J Lamberti, Raghav A Murthy
Percutaneous therapies for congenital heart disease have been evolving rapidly despite limited investment from industry. The Melody transcatheter pulmonary valve (Medtronic, Inc, Minneapolis, MN USA) replacement therapy represents an important advancement in this arena. It has been approved in the United States for use in the pulmonary position, on a Humanitarian Device Exemption status. Off-label use of the Melody transcatheter pulmonary valve has extended to the mitral, pulmonary, and aortic valves, especially in previously implanted valves with prosthetic valve degeneration...
February 9, 2018: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29430784/editorial-just-clip-it-then-reclip-it-again-expanding-populations-for-transcatheter-mitral-repair-and-options-for-recurrent-mitral-regurgitation
#15
Chad Kliger
No abstract text is available yet for this article.
February 2018: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29430431/minimally-invasive-mitral-valve-repair-in-a-woman-with-marfan-syndrome-and-type-b-dissection
#16
Mi Hee Lim, Hyung Gon Je, Sang Kwon Lee
We report the case of a patient with mitral regurgitation complicated by type B dissection and Marfan syndrome (MFS) who was managed successfully with minimally invasive mitral valve repair. Without type A aortic dissection or aortic root dilation, MFS patients may develop mitral valve regurgitation, as in this case, and need valve surgery to improve their symptoms and long-term survival. However, it is not clear that a full sternotomy and prophylactic aortic surgery are necessary. Although retrograde perfusion to the dissected aorta is controversial, our approach minimizes the risk of future anticipated aortic surgery in MFS patients...
February 2018: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29429630/transcatheter-aortic-valve-replacement-in-patients-with-severe-mitral-or-tricuspid-regurgitation-at-extreme-risk-for-surgery
#17
Stephen H Little, Jeffrey J Popma, Neal S Kleiman, G Michael Deeb, Thomas G Gleason, Steven J Yakubov, Stan Checuti, Daniel O'Hair, Tanvir Bajwa, Mubashir Mumtaz, Brijeshwar Maini, Alan Hartman, Stanley Katz, Newell Robinson, George Petrossian, John Heiser, William Merhi, B Jane Moore, Shuzhen Li, David H Adams, Michael J Reardon
OBJECTIVES: Patients with symptomatic severe aortic stenosis and severe mitral regurgitation or severe tricuspid regurgitation were excluded from the major transcatheter aortic valve replacement trials. We studied these 2 subgroups in patients at extreme risk for surgery in the prospective, nonrandomized, single-arm CoreValve US Expanded Use Study. METHODS: The primary end point was all-cause mortality or major stroke at 1 year. A favorable medical benefit was defined as a Kansas City Cardiomyopathy Questionnaire overall summary score greater than 45 at 6 months and greater than 60 at 1 year and with a less than 10-point decrease from baseline...
January 31, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29426020/to-clip-or-not-to-clip-can-we-predict-which-patients-with-functional-mitral-regurgitation-will-benefit-from-transcatheter-mitral-valve-repair
#18
EDITORIAL
Stephanie El Hajj, Sheldon E Litwin
No abstract text is available yet for this article.
February 6, 2018: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/29424749/an-unusual-cause-of-aortic-regurgitation-accessory-mitral-valve
#19
Mete Han Kızılkaya, Fahrettin Uysal, Özlem Mehtap Bostan, Volkan Yazıcıoğlu
No abstract text is available yet for this article.
February 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29421917/a-dieulafoy-s-lesion-in-a-duodenal-diverticulum-an-infrequent-cause-of-ugib
#20
Marina de Benito Sanz, Marta Cimavilla Román, Raúl Torres Yuste
We present the case of an 82-year-old man with a history of heart failure, mitral regurgitation, type 2 DM, hypertension, dilated cardiomyopathy and a paroxysmal atrial flutter. The patient was under treatment with Sintrom. The patient presented to the emergency department due to melenic depositions of a one day evolution and dietary vomiting. There was no rectal bleeding and the patient was admitted three months previously due to self-limited melena with a normal gastroscopy. Anemia of 8 g and an overdose of Sintrom was diagnosed...
February 9, 2018: Revista Española de Enfermedades Digestivas
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