keyword
MENU ▼
Read by QxMD icon Read
search

Activity monitor

keyword
https://www.readbyqxmd.com/read/29684878/occurrence-and-overlooked-sources-of-the-biocide-carbendazim-in-wastewater-and-surface-water
#1
Sylvain Merel, Saskia Benzing, Carolin Gleiser, Gina Di Napoli-Davis, Christian Zwiener
Carbendazim is a fungicide commonly used as active substance in plant protection products and biocidal products, for instance to protect facades of buildings against fungi. However, the subsequent occurrence of this fungicide and potential endocrine disruptor in the aqueous environment is a major concern. In this study, high resolution mass spectrometry shows that carbendazim can be detected with an increasing abundance from the source to the mouth of the River Rhine. Unexpectedly, the abundance of carbendazim correlates poorly with that of other fungicides used as active ingredients in plant protection products (r2 of 0...
April 20, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29684658/caught-in-between-system-for-in-flow-inactivation-of-enzymes-as-an-intermediary-step-in-plug-and-play-microfluidic-platforms
#2
Ana C Fernandes, Benjamin Petersen, Lars Møller, Krist V Gernaey, Ulrich Krühne
The need for fast and comprehensive characterization of biocatalysts has pushed the development of new screening platforms based on microfluidics, capable of monitoring several parameters simultaneously, with new configurations of liquid handling, sample treatment and sensing. Modular microfluidics allows the integration of these newly developed approaches in a more flexible way towards increasing applicability of the microfluidic chips to different types of biocatalysts and reactions. A highly relevant operation in such a system is biocatalyst inactivation, which can enable the precise control of reaction time by avoiding the continuation of the reaction in another module or connecting tubes...
April 20, 2018: New Biotechnology
https://www.readbyqxmd.com/read/29684636/increased-frequency-of-ccr7-cd4-t-cells-from-patients-with-primary-sj%C3%A3-gren-s-syndrome-an-indicator-of-disease-activity-rather-than-of-damage-severity
#3
Chunling Wu, Pingting Yang, Haina Liu, Weiguo Xiao, Lijuan Zhao
Expression of CCR7 on T cells has been reported to be associated with the lymphocytic migration and infiltration, which is recognized as a vital part of the pathogenesis of Primary Sjögren's syndrome (pSS). Here, we compared the expression of CCR7 on CD4+T cells between pSS patients and control groups, including healthy donors (HD) and patients with systemic lupus erythematosus (SLE) and examined correlations with disease activity and damage severity, which were evaluated by EULAR Sjögren's Syndrome Disease Activity Index (ESSDAI) and Sjogren's Syndrome Disease Damage Index (SSDDI), respectively...
April 20, 2018: Cytokine
https://www.readbyqxmd.com/read/29684352/nrf2-activation-protects-against-intratracheal-lps-induced-mouse-murine-acute-respiratory-distress-syndrome-by-regulating-macrophage-polarization
#4
Juan Wei, Guannan Chen, Xuan Shi, Huanping Zhou, Meiyun Liu, Yuanli Chen, Di Feng, Pengcheng Zhang, Lingmin Wu, Xin Lv
The transcription factor nuclear factor E2-related factor 2 (Nrf2) is known to control the expression of antioxidant response elements and cytoprotective genes and modulate inflammatory response, helping to ameliorate damage in many diseases. Exactly how Nrf2 regulates innate inflammatory homeostasis remains unclear. In this study, we provide in vitro and in vivo evidence that Nrf2 plays a crucial role in macrophage polarization and acute respiratory distress syndrome (ARDS). We conducted in vitro experiments using a mouse alveolar macrophage cell line as well as primary cultures of macrophages in which cells were exposed to lipopolysaccharide (LPS) or interferon-γ in order to mimic ARDS, in the presence or absence of the Nrf2 activator tert-butylhydroquinone (tBHQ)...
April 20, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29684351/stat3-activation-by-il-6-from-adipose-derived-stem-cells-promotes-endometrial-carcinoma-proliferation-and-metastasis
#5
Yijing Chu, Yan Wang, Wei Peng, Lin Xu, Meixin Liu, Jing Li, Xiaoyu Hu, Yan Li, Jianxin Zuo, Yuanhua Ye
Endometrial cancer is the most common gynaecological cancer, and its incidence is increasing. Obesity is a well-recognized risk factor for endometrial cancer, and the mechanisms by which adipose tissue influences tumour development remain controversial. In this study, we examined the high IL-6 level in the ADSCs supernatant following treatment of endometrial cancer cell CM. Then, the activation of STAT3, a major tumourigenic IL-6 effector, was examined in endometrial cancer cells. Conditioned ADSC medium was used to stimulate endometrial cancer cell growth in vitro...
April 20, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29684232/immune-checkpoint-inhibitor-therapy-in-patients-with-autoimmune-disease
#6
Douglas B Johnson, Kathryn E Beckermann, Daniel Y Wang
Immune checkpoint inhibitors have demonstrated efficacy across many cancer types in numerous clinical trials. However, because patients with preexisting autoimmune disease were excluded from these seminal trials, there are serious gaps in knowledge regarding the efficacy-and in particular the safety-of these transformative agents in patients with autoimmune disease. The safety of immune checkpoint inhibitors in this population has been an important concern, since these agents unleash immune activation, a potentially dangerous situation for patients with already heightened and aberrant immune function...
April 15, 2018: Oncology (Williston Park, NY)
https://www.readbyqxmd.com/read/29684004/the-neural-system-of-metacognition-accompanying-decision-making-in-the-prefrontal-cortex
#7
Lirong Qiu, Jie Su, Yinmei Ni, Yang Bai, Xuesong Zhang, Xiaoli Li, Xiaohong Wan
Decision-making is usually accompanied by metacognition, through which a decision maker monitors uncertainty regarding a decision and may then consequently revise the decision. These decisional metacognitive processes can occur prior to or in the absence of feedback. However, the neural mechanisms of metacognition remain controversial. One theory proposes an independent neural system for metacognition in the prefrontal cortex (PFC); the other, that metacognitive processes coincide and overlap with the systems used for the decision-making process per se...
April 23, 2018: PLoS Biology
https://www.readbyqxmd.com/read/29683922/a-review-of-accelerometer-based-activity-monitoring-in-cancer-survivorship-research
#8
Carolyn J Peddle-McIntyre, Vinicius Cavalheri, Terry Boyle, Joanne A McVeigh, Emily Jeffery, Brigid M Lynch, Jeff K Vallance
BACKGROUND: In the cancer survivorship context, physical activity and sedentary behaviour have been measured using different methods and tools. PURPOSE: To conduct a narrative review of published research in cancer survivor populations to summarise the quality and identify gaps in reporting on accelerometer data collection, data processing, and outcome measures in cancer survivors. METHODS: An initial PubMed® search of papers published in English was conducted in January 2017, and a final search was conducted in May 2017...
April 21, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29683919/hiit-in-the-real-world-outcomes-from-a-12-month-intervention-in-overweight-adults
#9
Melyssa Roy, Sheila M Williams, Rachel C Brown, Kim A Meredith-Jones, Hamish Osborne, Michelle Jospe, Rachael W Taylor
PURPOSE: Although high-intensity interval training (HIIT) and moderate-intensity continuous exercise have comparable health outcomes in the laboratory setting, effectiveness studies in real-world environments are lacking. The aim of this study was to determine the effectiveness of an unsupervised HIIT programme in overweight/obese adults over 12 months. METHODS: 250 overweight/obese adults could choose HIIT or current exercise guidelines of 30 minutes/day moderate-intensity exercise...
April 21, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29683652/impacts-of-glutaraldehyde-on-microbial-community-structure-and-degradation-potential-in-streams-impacted-by-hydraulic-fracturing
#10
Maria Fernanda Campa, Stephen M Techtmann, Caleb Gibson, Xiaojuan Zhu, Megan Patterson, Amanda Garcia de Matos Amaral, Nikea Ulrich, Shawn R Campagna, Christopher J Grant, Regina Lamendella, Terry C Hazen
The environmental impacts of hydraulic fracturing, particularly those of surface spills in aquatic ecosystems, are not fully understood. The goals of this study were to: (1) understand the effect of previous exposure to hydraulic fracturing fluids on aquatic microbial community structure and (2) examine the impacts exposure has on biodegradation potential of the biocide glutaraldehyde. Microcosms were constructed from hydraulic fracturing-impacted and non-hydraulic fracturing-impacted stream water within the Marcellus shale region in Pennsylvania...
April 23, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29683409/reclamation-of-grey-water-for-non-potable-purpose-using-pilot-scale-solar-photocatalytic-tubular-reactors
#11
S Saran, P Arunkumar, G Manjari, S P Devipriya
Application of pilot scale slurry type tubular photocatalytic reactor was tested for the decentralized treatment of actual grey water. The reactors were fabricated by reusing the locally available materials at low cost, operated in batch recycle mode with 25L of grey water. The influence of operational parameters such as catalysts concentration, initial slurry pH and addition of H2 O2 on COD abatement were optimized. The results illustrate that, Ag decorated TiO2 shows two-fold increase in COD abatement than pure TiO2 ...
April 23, 2018: Environmental Technology
https://www.readbyqxmd.com/read/29683406/influence-of-anxiety-and-alexithymia-on-brain-activations-associated-with-the-perception-of-others-pain-in-autism
#12
Amandine Lassalle, Nicole R Zürcher, Carlo A Porro, Francesca Benuzzi, Loyse Hippolyte, Eric Lemonnier, Jakob Åsberg Johnels, Nouchine Hadjikhani
The circumstances under which empathy is altered in ASD remain unclear, as previous studies did not systematically find differences in brain activation between ASD and controls in empathy-eliciting paradigms, and did not always monitor whether differences were primarily due to ASD "per se", or to conditions overlapping with ASD, such as alexithymia and anxiety. Here, we collected fMRI data from 47 participants (22 ASD) viewing pictures depicting hands and feet of unknown others in painful, disgusting, or neutral situations...
April 23, 2018: Social Neuroscience
https://www.readbyqxmd.com/read/29683363/cardiovascular-autonomic-response-to-orthostatic-stress-under-hypoxia-in-patients-with-spinal-cord-injury
#13
Shu-Chun Huang, Kuo-Cheng Liu, Alice M K Wong, Shih-Chieh Chang, Jong-Shyan Wang
Huang, Shu-Chun, Kuo-Cheng Liu, Alice M.K. Wong, Shih-Chieh Chang, and Jong-Shyan Wang. Cardiovascular autonomic response to orthostatic stress under hypoxia in patients with spinal cord injury. High Alt Med Biol. 00:000-000, 2018. AIMS: Determining whether systemic hypoxia aggravates the severity of autonomic cardiovascular dysfunction in orthostatic stress among patients with spinal cord injuries (SCIs). METHODS: Twenty-four male patients with chronic SCI whose neurological levels were above T6 were recruited...
April 23, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29683307/maternity-care-update-labor-and-delivery
#14
Andrew Smith, Wendy B Barr, Erin Bassett-Novoa, Nicholas LeFevre
Labor is defined as contractions with cervical change and active labor starts when the cervix is dilated 6 cm. Updated labor curves and definitions should be used to define labor dystocia. Oxytocin and amniotomy have important roles in the management of labor dystocia. Structured intermittent fetal monitoring should be considered for women with low-risk pregnancies but continuous electronic fetal monitoring still is used most commonly. Moderate fetal heart rate variability is the most reliable marker of fetal well-being...
April 2018: FP Essentials
https://www.readbyqxmd.com/read/29683262/celecoxib-enhances-the-therapeutic-efficacy-of-epirubicin-for-novikoff-hepatoma-in-rats
#15
Tian-Huei Chu, Hoi-Hung Chan, Tsung-Hui Hu, E-Ming Wang, Yi-Ling Ma, Shih-Chung Huang, Jian-Ching Wu, Yi-Chen Chang, Wen-Tsan Weng, Zhi-Hong Wen, Deng-Chyang Wu, Yi-Ming Arthur Chen, Ming-Hong Tai
Epirubicin is a chemotherapy agent for hepatocellular carcinoma (HCC). However, the outcome of HCC patients receiving epirubicin remains unsatisfactory. Moreover, our previous study indicated that celecoxib suppresses HCC progression and liver cancer stemness. This study evaluated the potential of celecoxib to serve as a complementary therapy during epirubicin treatment. Cell proliferation, apoptosis, invasiveness, and anchorage-independent growth were analyzed in hepatoma cells. Therapeutic efficacy was validated in rat orthotopic Novikoff hepatoma...
April 23, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29683219/response-of-consumer-and-research-grade-indoor-air-quality-monitors-to-residential-sources-of-fine-particles
#16
Brett C Singer, William W Delp
The ability to inexpensively monitor PM2.5 to identify sources and enable controls would advance residential indoor air quality (IAQ) management. Consumer IAQ monitors incorporating low-cost optical particle sensors and connections with smart home platforms could provide this service if they reliably detect PM2.5 in homes. In this study, particles from typical residential sources were generated in a 120 m3 laboratory and time-concentration profiles were measured with seven consumer monitors (2-3 units each), two research monitors (Thermo pDR-1500, MetOne BT-645), a Grimm Mini Wide-Range Aerosol Spectrometer (GRM), and a Tapered Element Oscillating Microbalance with Filter Dynamic Measurement System (FDMS), a federal equivalent method (FEM) for PM2...
April 23, 2018: Indoor Air
https://www.readbyqxmd.com/read/29682967/in-vivo-two-photon-fluorescence-imaging-of-the-activity-of-the-inflammatory-biomarker-lta4h-in-a-mouse-pneumonia-model
#17
Hui Wang, Ke Xue, Ping Li, Yuyun Yang, Zixu He, Wei Zhang, Wen Zhang, Bo Tang
Severe atmospheric haze caused by industrial pollution has severely affected human health and led to the increasing incidence of cardiopulmonary diseases, including pneumonia. Conventional methods for diagnosis of pneumonia are complicated and tedious, and current clinical imaging techniques might cause organ injuries to some extent. Therefore, an accurate, fast, and intact imaging method must be developed to diagnose pneumonia in the early stages. In this study, we propose a new two-photon fluorescence probe, named as ASPC, for detection of the activity of the inflammatory biomarker LTA4H through specific recognition and cleavage of amides containing the unnatural amino acid L-AspBzl...
April 23, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29682861/catalytic-power-of-enzymes-decreases-with-temperature-new-insights-for-understanding-soil-c-cycling-and-microbial-ecology-under-warming
#18
Gaël Alvarez, Tanvir Shahzad, Laurence Andanson, Michael Bahn, Matthew D Wallenstein, Sébastien Fontaine
Most current models of soil C dynamics predict that climate warming will accelerate soil C mineralization, resulting in a long-term CO2 release and positive feedback to global warming. However, ecosystem warming experiments show that CO2 loss from warmed soils declines to control levels within a few years. Here, we explore the temperature-dependence of enzymatic conversion of polymerised soil organic C (SOC) into assimilable compounds, which is presumed the rate-limiting step of SOC mineralization. Combining literature review, modelling and enzyme assays, we studied the effect of temperature on activity of enzymes considering their thermal inactivation and catalytic activity...
April 23, 2018: Global Change Biology
https://www.readbyqxmd.com/read/29681783/imaging-and-methotrexate-response-monitoring-of-systemic-inflammation-in-arthritic-rats-employing-the-macrophage-pet-tracer-18-f-fluoro-peg-folate
#19
Durga M S H Chandrupatla, Gerrit Jansen, Elise Mantel, Philip S Low, Takami Matsuyama, René P Musters, Albert D Windhorst, Adriaan A Lammertsma, Carla F M Molthoff, Conny J van der Laken
Background: In rheumatoid arthritis, articular inflammation is a hallmark of disease, while the involvement of extra-articular tissues is less well defined. Here, we examined the feasibility of PET imaging with the macrophage tracer [18 F]fluoro-PEG-folate, targeting folate receptor β (FR β ), to monitor systemic inflammatory disease in liver and spleen of arthritic rats before and after methotrexate (MTX) treatment. Methods: [18 F]Fluoro-PEG-folate PET scans (60 min) were acquired in saline- and MTX-treated (1 mg/kg, 4x) arthritic rats, followed by tissue resection and radiotracer distribution analysis...
2018: Contrast Media & Molecular Imaging
https://www.readbyqxmd.com/read/29681649/source-and-fractionation-controls-on-subduction-related-plutons-and-dike-swarms-in-southern-patagonia-torres-del-paine-area-and-the-low-nb-ta-of-upper-crustal-igneous-rocks
#20
Othmar Müntener, Tanya Ewing, Lukas P Baumgartner, Mélina Manzini, Thibaud Roux, Pierre Pellaud, Luc Allemann
The subduction system in southern Patagonia provides direct evidence for the variability of the position of an active continental arc with respect to the subducting plate through time, but the consequences on the arc magmatic record are less well studied. Here we present a geochemical and geochronological study on small plutons and dykes from the upper crust of the southern Patagonian Andes at ~ 51°S, which formed as a result of the subduction of the Nazca and Antarctic plates beneath the South American continent...
2018: Contributions to Mineralogy and Petrology. Beiträge Zur Mineralogie und Petrologie
keyword
keyword
10188
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"