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https://www.readbyqxmd.com/read/27911071/severe-brain-injury-in-massachusetts-assessing-the-continuum-of-care
#1
Laura Lorenz, Gabrielle Katz
Acquired brain injury (ABI) is a major public health problem in Massachusetts (Hackman et al, 2014) and includes traumatic brain injury (TBI), stroke, ABI-related infectious diseases, metabolic disorders affecting the central nervous system (brain and spinal cord), and brain tumor. Advances in emergency medical care and neurosurgery mean that more people are surviving severe traumatic brain injury (Trexler et al, 2014). Yet many patients with severe TBI in particular, are not receiving inpatient services after initial treatment (Hackman et al, 2014; CDC, 2014) or later that are known to be effective (Malec & Kean, 2015; Lewis & Horn, 2015; BI Commission, 2011; Kolakowsky-Hayner et al, 2000; Interviews)...
December 10, 2015: Issue Brief
https://www.readbyqxmd.com/read/27909637/the-impact-of-hope-and-resilience-on-multiple-factors-in-neurosurgical-patients
#2
REVIEW
Devika Duggal, Amanda Sacks-Zimmerman, Taylor Liberta
The purpose of the present article is to outline and review the impact of stable psychological characteristics on the emotional and functional outcomes of neurosurgical patients. Neurosurgical patients face adversity as inherent to their diagnoses and, consequently, experience emotional distress. Despite commonalities in diagnoses, diverse outcomes are seen post-neurosurgery, which are influenced by psychological factors. Therefore, an understanding of neurosurgical patients' behavior, thoughts, and feelings surrounding their diagnoses, informed by psychological concepts, is important for both neuropsychology and neurosurgery...
October 26, 2016: Curēus
https://www.readbyqxmd.com/read/27909194/severity-assessment-and-scoring-for-neurosurgical-models-in-rodents
#3
Sarah Pinkernell, Katrin Becker, Ute Lindauer
The most important acute neurological diseases seen at neurosurgery departments are traumatic brain injuries (TBI) and subarachnoid hemorrhages (SAH). In both diseases the pathophysiological sequela are complex and have not been fully understood up to now, and rodent models using rats and mice are most suitable for the investigation of the pathophysiological details. In both models, surgery is performed under anesthesia, followed by assessment of their functional outcome and behavioral testing before brain tissue analysis after euthanasia...
December 2016: Laboratory Animals
https://www.readbyqxmd.com/read/27858384/efficacy-of-lumboperitoneal-shunting-in-patients-with-normal-pressure-hydrocephalus
#4
Mehmet Akif Bayar, Ayhan Tekiner, Haydar Celik, Ali Yilmaz, Guner Menekse, Timur Yildirim, Fatih Alagoz, Yahya Guvenc, Yavuz Erdem
AIM: To evaluate the effectiveness of lumboperitoneal shunt procedures in the treatment of normal pressure hydrocephalus Material and Methods: A medical record review was conducted to obtain demographic, clinical, laboratory data, as well as pre-, intra, -post-operative details of 65 patients who underwent lumboperitoneal shunt surgery between January 1, 2001 and January 1, 2014 in the Neurosurgery Clinics of Ankara Training and Research Hospital and Ankara Numune Hospital. RESULTS: At about 3 months after LP shunt surgery, the complaint of headache resolved in almost all patients; at the end of the first year, while statistically significant improvements were noted in the Modified Rankin Scores and Mini Mental Test Scores, gait disturbance, urinary incontinence and cognitive functions improved by 86%, 72% and 65% of the patients, respectively...
October 14, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27836702/advancement-of-surgical-visualization-methods-a-comparison-study-between-traditional-microscopic-surgery-and-a-novel-robotic-optoelectronic-visualization-tool-for-spinal-surgery
#5
Marc D Moisi, Kimberly Hoang, R Shane Tubbs, Jeni Page, Christian Fisahn, David Paulson, Shiveindra Jeyamohan, Johnny Delashaw, David Hanscom, Rod J Oskouian, Jens Chapman
INTRODUCTION: The operative microscope has become instrumental in aiding surgeons during key microdissection with greater safety and detail. An exoscope offers similar detail with improved functionality and greater implications for live-teaching and improved operating-room flow. METHODS: Eleven senior neurosurgery residents and fellows performed unilateral, single-level laminotomies on fresh cadavers using an operating microscope and exoscope. Three attending spine surgeons blinded for the visualization technique used then reviewed and graded each decompression...
November 8, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27833756/presurgical-assessment-of-cognitive-function-in-pediatric-brain-tumor-patients-feasibility-and-initial-findings
#6
Jennifer C Thigpen, Matthew Pearson, Kristen E Robinson, Charissa Andreotti, Jennifer P Dunbar, Kelly H Watson, Leandra Dejardins, Lindsay Holmes, Rebecca Byram, Claire Fraley, Bruce E Compas
BACKGROUND: Establishing a presurgical baseline of neurocognitive functioning for pediatric brain tumor patients is a high priority to identify level of functioning prior to medical interventions. However, few studies have obtained adequate samples of presurgery assessments. METHODS: This study examines the feasibility of completing tests to assess pre-surgical neurocognitive functioning in 59 identified pediatric brain tumor patients. RESULTS: Eighty-five percent of patients (n = 50) were referred by the neurosurgery team before surgery and 83% of patients (n = 49) enrolled in the study...
December 2016: Neuro-oncology Practice
https://www.readbyqxmd.com/read/27801398/-surgical-treatment-of-%C3%A2-mirror%C3%A2-aneurysms-of-the-internal-carotid-artery
#7
A O Sosnov, A V Dubovoi, V S Kiselev, D M Galaktionov, K S Ovsyannikov, A V Cherepanov, T K Istomina
BACKGROUND: A relatively high occurrence of "mirror" aneurysms of the anterior cerebral circulation in neurosurgical practice necessitates generalization of experience of using different surgical approaches. The choice of treatment is usually associated with the number of surgical stages. MATERIAL AND METHODS: Forty nine patients (19 males and 30 females) with mirror aneurysms of the anterior circulation underwent one- and two-step surgery at the Novosibirsk Federal Center of Neurosurgery in 2013-2015...
2016: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://www.readbyqxmd.com/read/27792692/-white-matter-hyperintensities-and-cognitive-function-in-patients-with-late-onset-mania
#8
Jesús Ramírez-Bermúdez, Roger Carrillo-Mezo, Carmen Atriano, Dora Sánchez, Óscar Marrufo-Meléndez, Cecilia Berlanga, Adilia Guadamuz, Jesús Taboada, Camilo Ríos
Bipolar disorder is characterized by affective episodes in the mania-depression spectrum. Ninety per cent of the cases have an onset before age 50. In the patients with late onset mania, white matter hyperintensities (WMH) may be seen in the MRI FLAIR sequence, although these are of uncertain significance. A case-control study was done, including patients with late onset mania attended at the National Institute of Neurology and Neurosurgery, as well as healthy controls which were paired by age, sex, and academic level...
September 2016: Gaceta Médica de México
https://www.readbyqxmd.com/read/27790509/outcome-analysis-in-cases-of-spinal-conus-cauda-ependymoma
#9
Srikant Balasubramaniam, Devendra K Tyagi, Ketan I Desai, Mohnish P Dighe
INTRODUCTION: One half of all central nervous system ependymomas, arise within the spinal canal and about 40% of these arise from filum terminale. The myxopapillary variant of spinal ependymoma almost exclusively occurs in the lumbosacral region and they are histologically designated as Grade I. Long term control is best achieved by gross total removal at the initial operation. There is as yet no consensus on the management of incompletely excised tumour. Opinions regarding radiotherapy are controversial and the indications are empirical...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27769951/rapid-and-minimally-traumatic-replacement-of-stimulator-extension-cables-technical-note-on-a-novel-use-for-sternal-wire
#10
Fraser Henderson, Istvan Takacs
BACKGROUND: Troubleshooting of deep brain stimulators (Activa SC/PC/RC Medtronic PLC) sometimes results in a decision to replace a tunneled stretch-coil extension cable. We present a simple technique to accomplish this atraumatically without a tunneling tool. OBJECTIVES: In the treatment of patients with deep brain stimulators, complication avoidance and efficiency of operative time are paramount. We sought to find the most safe, effective, and rapid method for performing the conceptually-simple yet technically-nuanced act of replacing lead extension cables...
October 18, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27759681/beyond-the-cyst-the-many-contributions-of-isadore-tarlov-1905-1977-to-contemporary-neurosurgical-practice
#11
Anand Kaul, Sunil Manjila, Jonathan P Miller
: Isadore Max Tarlov (1905-1977) is primarily remembered for his 1938 description of the eponymous perineural "Tarlov cyst." However, during his long career as a neurosurgeon and researcher, he was responsible for many other observations and inventions that influenced the development of neurosurgery in the 20th century. While studying at Johns Hopkins Medical School he was acquainted with Walter Dandy, and he became the first resident to study under Wilder Penfield at the newly formed Montreal Neurological Institute...
November 2016: Neurosurgery
https://www.readbyqxmd.com/read/27746701/regional-versus-general-anaesthesia-for-improved-cognitive-function-after-procedures-other-than-cardiac-surgery-or-neurosurgery-in-adult-and-paediatric-patients
#12
Michael H Andreae, Arthur Atchabahian, Aileen M McCrillis, Jerry Y Chao, Suzuko Suzuki, Shlomo Shinnar, Charles B Hall, Richard B Lipton
This is the protocol for a review and there is no abstract. The objectives are as follows: The objective of this review is to compare the effects of regional versus general anaesthesia on cognitive function after procedures other than cardiac surgery or neurosurgery in adult and in paediatric patients.
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27727417/vakenkirurgi-vid-l%C3%A3-ggradiga-gliom-rekommenderas-goda-resultat-av-7-%C3%A3-rs-erfarenheter-i-link%C3%A3-ping
#13
Peter Milos, Kerstin Metcalf, Patrick Vigren, Hans Lindehammar, Malin Nilsson, Sverre Boström
Awake craniotomy for brain tumours  Awake neurosurgery is a useful method in lesions near eloquent brain areas, particularly low-grade gliomas.The aim is to maximise tumour resection and preserve neurological function. We performed 40 primary awake surgeries and 8 residual surgeries. Patients were operated awake throughout the procedure or with a laryngeal mask and general anaesthesia during the opening stage and then awake during intracerebral surgery. Language and motor function were mapped with direct cortical stimulation, motor evoked potential and standardised neurological testing...
October 11, 2016: Läkartidningen
https://www.readbyqxmd.com/read/27725800/assessment-of-age-related-morphometric-changes-of-subcortical-structures-in-healthy-people-using-ultra-high-field-7-tesla-magnetic-resonance-imaging
#14
Xue-Yuan Wang, Lei Zhao, Tao Yu, Liang Qiao, Duan-Yu Ni, Guo-Jun Zhang, Yong-Jie Li
Objective: To assess the age-related morphometric changes of subcortical structures in healthy people. Materials and Methods: Ultra-high field 7 tesla magnetic resonance (MR) imaging in humans was used to visualize the subcortical structures of healthy young, middle-aged and elderly participants. Using the magnetization-prepared two rapid acquisition gradient echo (MP2RAGE) sequence, we assessed the visibility of the margins of the thalamus and white matter in the thalamus, as well as the anterior commissure (AC) and posterior commissure (PC) length, the maximal height of the thalamus, the half width of the third ventricle and the distance between the AC and the center of the mammillothalamic tract (MTT) at the level of the AC-PC plane...
2016: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/27698888/mirna-regulation-of-sirtuin-1-expression-in-human-astrocytoma
#15
Sara Giovanna Romeo, Alfredo Conti, Francesca Polito, Chiara Tomasello, Valeria Barresi, Domenico La La Torre, Maria Cucinotta, Flavio Filippo Angileri, Marcello Bartolotta, Rosa Maria Di Giorgio, M'Hammed Aguennouz
Sirtuins are a family of 7 histone deacetylases largely involved in the regulation of cell proliferation, survival and death. The role of sirtuins in tumorigenesis and cancer progression has been previously studied in certain cancer types. Few studies have investigated sirtuin expression in gliomas, with controversial results. The aim of the present study was to investigate the expression of sirtuin-1 (Sirt-1) in diffuse astrocytoma [low grade astrocytoma (LGA)], anaplastic astrocytoma (AA) and glioblastoma multiforme (GBM) and in primary glioma cell lines: PLGAC (primary LGA cells); PAAC (primary AA cells); and PGBMC (primary GBM cells)...
October 2016: Oncology Letters
https://www.readbyqxmd.com/read/27698736/use-of-deep-brain-stimulation-for-major-affective-disorders
#16
Kuanqing Mi
The multifactorial etiology of major affective disorders, such as major depression and bipolar disorder, poses a challenge for identification of effective treatments. In a substantial number of patients, psychopharmacologic treatment does not lead to effective continuous symptom relief. The use of deep brain stimulation (DBS) for treatment-resistant patients is an investigational approach that has recently produced promising results. The recent development of safer stereotaxic neurosurgery, and the combination with functional neuroimaging to map the affected brain circuits, have led to the investigation of DBS as a potential strategy to treat major mood disorders...
October 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27695535/spinal-epidural-angiolipomas-clinical-characteristics-management-and-outcomes
#17
Sofiene Bouali, Nidhal Maatar, Asma Bouhoula, Khansa Abderrahmen, Imed Ben Said, Adnen Boubaker, Jalel Kallel, Hafedh Jemel
PURPOSE: The spinal epidural angiolipomas are rare expansive processes made of mature lipomatous and angiomatous elements. They often have a benign character. Their etiology, pathogenesis remains uncertain, and it is a cause of spinal cord compression. The magnetic resonance imaging is the most important neuroradiological examination. Histological examination is the only examination to confirm the diagnosis. Surgery is the treatment of choice. METHODS: A retrospective study of all patients operated on for a spinal epidural angiolipoma at the Department of Neurosurgery at the National Institute of Neurology of Tunis between January 2000 and December 2014 (15 years) was performed...
October 2016: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/27695239/surgical-resection-of-low-grade-gliomas-in-eloquent-areas-with-the-guidance-of-the-preoperative-functional-magnetic-resonance-imaging-and-craniometric-points
#18
Ahmed Abdullah, Hisham El Shitany, Waleed Abbass, Amr Safwat, Amr K Elsamman, Ehab El Refaee
OBJECTIVES: Surgical resection of low-grade gliomas (LGGs) in eloquent areas is one of the challenges in neurosurgery, using assistant tools to facilitate effective excision with minimal postoperative neurological deficits has been previously discussed (awake craniotomy and intraoperative cortical stimulation); however, these tools could have their own limitations thus implementation of a simple and effective technique that can guide to safe excision is needed in many situations. MATERIALS AND METHODS: The authors conducted a retrospective analysis of a prospectively collected data of 76 consecutive surgical cases of LGGs of these 21 cases were situated in eloquent areas...
October 2016: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/27688008/resection-of-tumors-of-the-third-ventricle-involving-the-hypothalamus-effects-on-body-mass-index-using-a-dedicated-surgical-approach
#19
Pietro Mortini, Filippo Gagliardi, Michele Bailo, Nicola Boari, Antonella Castellano, Andrea Falini, Marco Losa
Resection of large lesions growing into the third ventricle is considered nowadays still a demanding surgery, due to the high risk of severe endocrine and neurological complications. Some neurosurgical approaches were considered in the past the procedures of choice to access the third ventricle, however they were burden by endocrine and neurological consequences, like memory loss and epilepsy. We report here the endocrine and functional results in a series of patients operated with a recently developed approach specifically tailored for the resection of large lesions growing into the third ventricle...
September 29, 2016: Endocrine
https://www.readbyqxmd.com/read/27676786/healthcare-pathway-after-sever-traumatic-brain-injury-about-a-tunisian-population
#20
Soumaya Boudokhane, Amine Kalai, Aymen Haj Salah, Houda Migaou, Sana Salah, Anis Jellad, Mourad Gahbiche, Zohra Ben Salah Frih
OBJECTIVE: The aim of our study was to determine the demographic characteristics and the pathway of severe traumatic brain injury (STBI) victims in the Tunisian population. MATERIAL/PATIENTS AND METHODS: Our study included 26 patients victims of STBI hospitalized in intensive care unit, among 450 traumatic head injuries admitted to the Teaching Hospital of Fattouma Bourguiba in Monastir during the year 2014. The studied parameters were: demographic characteristics of the population, circumstances of the accident, transport modalities to the hospital, assessments of the injury types, duration of coma, length of hospitalization in the Intensive Care Unit (ICU) and finally the discharge mode after the ICU stay (transfer to neurosurgery ward, to rehabilitation unit, or home discharged)...
September 2016: Annals of Physical and Rehabilitation Medicine
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