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https://www.readbyqxmd.com/read/28523744/bioinspired-ultratough-hydrogel-with-fast-recovery-self-healing-injectability-and-cytocompatibility
#1
Sara Azevedo, Ana M S Costa, Amanda Andersen, Insung S Choi, Henrik Birkedal, João F Mano
Inspired by the mussel byssus adhesiveness, a highly hydrated polymeric structure is designed to combine, for the first time, a set of interesting features for load-bearing purposes. These characteristics include: i) a compressive strength and stiffness in the MPa range, ii) toughness and the ability to recover it upon successive cyclic loading, iii) the ability to quickly self-heal upon rupture, iv) the possibility of administration through minimally invasive techniques, such as by injection, v) the swelling ratio being adjusted to space-filling applications, and vi) cytocompatibility...
May 19, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28521787/robot-assisted-thoracoscopic-lobectomy-as-treatment-of-a-giant-bulla
#2
Rosa Roemers, Kornelis Patberg, Caroline van de Wauwer, Tam Nguyen, Ghada Shahin
BACKGROUND: A bulla is a marked enlarged space within the parenchyma of the lung. Bullae may cause dyspnea by compressing healthy lung parenchyma and can cause a pneumothorax. Also, bullae are associated with malignancy, therefore surgical bullectomy is indicated on preventive basis. This case is unique and therefore valuable because of the remarkable presentation, innovative treatment and the spectacular improvement of lung function and socio-economic performance of the patient. CASE PRESENTATION: In this case report we describe the presentation, minimally invasive surgical treatment by means of a robot-assisted lobectomy and postoperative outcome of a young patient with a giant congenital bulla of the left upper lobe...
May 18, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28515450/microfluidic-sorting-of-cells-by-viability-based-on-differences-in-cell-stiffness
#3
Muhymin Islam, Hannah Brink, Syndey Blanche, Caleb DiPrete, Tom Bongiorno, Nicholas Stone, Anna Liu, Anisha Philip, Gonghao Wang, Wilbur Lam, Alexander Alexeev, Edmund K Waller, Todd Sulchek
The enrichment of viable cells is an essential step to obtain effective products for cell therapy. While procedures exist to characterize the viability of cells, most methods to exclude nonviable cells require the use of density gradient centrifugation or antibody-based cell sorting with molecular labels of cell viability. We report a label-free microfluidic technique to separate live and dead cells that exploits differences in cellular stiffness. The device uses a channel with repeated ridges that are diagonal with respect to the direction of cell flow...
May 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28515288/motor-recovery-beginning-23-years-after-ischemic-stroke
#4
Peter Sörös, Robert Teasell, Daniel F Hanley, J David Spence
It is widely believed that most stroke recovery occurs within 6 months, with little benefit of physiotherapy or other modalities beyond a year. We report a remarkable case of stroke recovery beginning 23 years after a severe stroke due to embolization from the innominate artery and subclavian artery, resulting from compression of the right subclavian artery by a cervical rib. The patient had a large right fronto-parietal infarction with severe left hemiparesis, and a totally non-functional spastic left hand...
May 17, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28514894/successful-repair-of-acute-type-b-and-retrograde-type-a-aortic-dissection-with-kidney-ischemia
#5
Jeko M Madjarov, Michael G Katz, Hector Crespo-Soto, Svetozar Madzharov, Timothy Roush, Francis Robicsek
Acute dissection of thoracic aorta carries a risk of renal ischemia followed by the development of a kidney failure. The optimal surgical and nonsurgical management of these patients, timing of intervention, and the factors predicting renal recovery are not well delineated and remain controversial. We present a case of acute type B thoracic aortic dissection with left kidney ischemia. Evaluation of renal function was performed by the means of internationally accepted Risk, Injury, Failure, Loss of kidney function, End stage kidney disease and Acute Kidney Injury Network classifications for acute kidney injury, renal duplex sonography, and intravascular ultrasound that demonstrated left renal artery dissection with a flap completely compressing the true lumen...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28508100/cervical-radiculopathy-combined-with-cervical-myelopathy-prevalence-and-characteristics
#6
Byung-Wan Choi, Sung-Soo Kim, Dong-Hyun Lee, Ji-Wan Kim
Patients with cervical myelopathy may experience symptoms of radiculopathy, and it is not easy to determine whether these symptoms are caused by the myelopathy itself or by a radiculopathy accompanied by root compression. Therefore, we aimed to investigate the prevalence of radiculopathy combined with cervical myelopathy and to evaluate the characteristics of cervical myelopathy with or without radiculopathy. We enrolled 127 patients with cervical myelopathy in this retrospective study and reviewed their medical records and magnetic resonance imaging findings...
May 15, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28496513/dog-footprint-in-the-heart
#7
Hassan Aghajani, Shahrooz Yazdani, Seyed Khalil Forouzan Nia, Hamed Vahidi, Faezeh Aghajani
Cardiac manifestations of the hydatid cyst are relatively uncommon. Cardiac involvement may lead to the compression of vital organs, pulmonary hypertension, pericardial effusion, and even anaphylaxis. A 45-year-old woman presented to the Emergency Department of Tehran Heart Center with chest pain. Cardiac examination revealed relatively muffled heart sounds. Echocardiography demonstrated a round echolucent well-defined mass (47 × 25 mm) on the base and the mid lateral wall of the left ventricle (LV) without septation...
October 3, 2016: Journal of Tehran Heart Center
https://www.readbyqxmd.com/read/28482434/-clinical-diagnosis-and-management-of-cervical-spondylotic-amyotrophy
#8
Y K Meng, J Zhang, Y Yang, L L Zhou, T F Yan, Y Wang, H S Yang, G D Shi, D Y Chen, J G Shi, Y F Guo, L S Jia
Objective: To investigate the clinical characteristics and surgical treatment of cervical spondylotic amyotrophy. Methods: Thirteen patients(13 man) with proximal (10) and distal(3) cervical spondylotic amyotrophy between November 2014 and September 2016 were included in this study. The average age of the patients was 55 (range, 47-66) years. The sex, age, clinical course, type of amyotrophy, lesion segment and postdecompression improvement in muscle power were reviewed. Results: Of 13 cervical spondylotic amyotrophy patients, 9 were performed on with cervical disectomy, 2 were performed on with cervical posterior operation, 2 remainding patients received nonoperative treatment...
May 9, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28472498/busybee-web-metagenomic-data-analysis-by-bootstrapped-supervised-binning-and-annotation
#9
Cedric C Laczny, Christina Kiefer, Valentina Galata, Tobias Fehlmann, Christina Backes, Andreas Keller
Metagenomics-based studies of mixed microbial communities are impacting biotechnology, life sciences and medicine. Computational binning of metagenomic data is a powerful approach for the culture-independent recovery of population-resolved genomic sequences, i.e. from individual or closely related, constituent microorganisms. Existing binning solutions often require a priori characterized reference genomes and/or dedicated compute resources. Extending currently available reference-independent binning tools, we developed the BusyBee Web server for the automated deconvolution of metagenomic data into population-level genomic bins using assembled contigs (Illumina) or long reads (Pacific Biosciences, Oxford Nanopore Technologies)...
May 2, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28468657/hsya-alleviates-secondary-neuronal-death-through-attenuating-oxidative-stress-inflammatory-response-and-neural-apoptosis-in-sd-rat-spinal-cord-compression-injury
#10
Jun-Peng Pei, Li-Hong Fan, Kai Nan, Jia Li, Xiao-Qian Dang, Kun-Zheng Wang
BACKGROUND: Hydroxysafflor yellow A (HSYA) is a major active component of yellow pigment extracted from safflowers; this compound possesses potent neuroprotective effects both in vitro and in vivo. However, underlying mechanism of HSYA is not fully elucidated. The present study investigated the protective effects of HSYA in rat spinal cord compression injury model and related mechanisms involved. METHODS: Sprague-Dawley rats were divided as Sham, Control, and HSYA groups (n = 30 per group)...
May 3, 2017: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/28466937/transparent-flexible-and-stretchable-ws2-based-humidity-sensors-for-electronic-skin
#11
Huayang Guo, Changyong Lan, Zhifei Zhou, Peihua Sun, Dapeng Wei, Chun Li
Skin-mountable chemical sensors using flexible chemically sensitive nanomaterials are of great interest for electronic skin (e-skin) application. To build these sensors, the emerging atomically thin two-dimensional (2D) layered semiconductors could be a good material candidate. Herein, we show that a large-area WS2 film synthesized by sulfurization of a tungsten film exhibits high humidity sensing performance both in natural flat and high mechanical flexible states (bending curvature down to 5 mm). The conductivity of as-synthesized WS2 increases sensitively over a wide relative humidity range (up to 90%) with fast response and recovery times in a few seconds...
May 18, 2017: Nanoscale
https://www.readbyqxmd.com/read/28465126/cryotherapy-with-dynamic-intermittent-compression-improves-recovery-from-revision-total-knee-arthroplasty
#12
Jérôme Murgier, J Cailliez, M Wargny, P Chiron, E Cavaignac, J M Laffosse
BACKGROUND: The goal of this study was to assess the efficacy of cryotherapy with dynamic intermittent compression (CDIC) in relieving postoperative pain, decreasing blood loss, and improving functional scores after revision total knee arthroplasty (rTKA). METHODS: We conducted a prospective case-control study (level of evidence: I) to evaluate the efficacy of CDIC on postoperative bleeding, pain, and functional outcomes after rTKA. Forty-three cases were included at a single institution and divided in 2 groups: a control group without CDIC (n = 19) and an experimental group with CDIC (n = 24)...
March 31, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28461887/recovery-property-of-double-network-hydrogel-containing-mussel-inspired-adhesive-moiety-and-nano-silicate
#13
Yuan Liu, Bruce P Lee
Altough double network (DN) hydrogels are extremly tough, they are irreversibly softened during large strain deformation. We incorporated mussel-inspired adhesive moiety, catechol, and a synthetic nano-silicate, Laponite, into DN to examine the effect of strong, reversible crosslinks on the DN's ability to recover its mechanical properties during successive loading cycles. The introduction of catechol and Laponite drastically increased the compressive strength and toughness of DN without compromising the compliance of the hydrogel...
October 28, 2016: Journal of Materials Chemistry. B, Materials for Biology and Medicine
https://www.readbyqxmd.com/read/28461274/complete-removal-of-the-epitrochleoanconeus-muscles-in-patients-with-cubital-tunnel-syndrome-results-from-a-small-prospective-case-series
#14
Godard C W de Ruiter, Sjoerd G van Duinen
BACKGROUND: Sometimes during surgery for cubital syndrome an anomalous muscle called the epitrochleoanconeus is encountered. Different surgical strategies how to decompress the ulnar nerve in the presence of this muscle have been proposed, including transection of the muscle, resection, or subcutaneous transposition of the ulnar nerve. Because of the low incidence, there is no consensus on what type of surgical treatment can best be performed. In this study, we prospectively followed a small series of patients, in which the muscle was resected...
April 28, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28459687/codingflow-enable-video-coding-for-video-stabilization
#15
Shuaicheng Liu, Mingyu Li, Shuyuan Zhu, Bing Zeng
Video coding focuses on reducing data size of videos. Video stabilization targets at removing shaky camera motions. In this work, we enable video coding for video stabilization by constructing the camera motions based on the motion vectors employed in the video coding. The existing stabilization methods rely heavily on image features for the recovery of camera motions. However, feature tracking is time-consuming and prone to errors. On the other hand, nearly all captured videos have been compressed before any further processing and such a compression has produced a rich set of block-based motion vectors that can be utilized for estimating the camera motion...
April 24, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28458950/carotid-cavernous-fistula-after-percutaneous-balloon-compression-for-trigeminal-neuralgia-endovascular-treatment-with-coils
#16
Luana A M Gatto, Rafaella Tacla, Gelson L Koppe, Zeferino Demartini Junior
BACKGROUND: Percutaneous ganglyolysis treatment of trigeminal neuralgia is rarely associated with vascular complications, such as hematoma, subarachnoid hemorrhage, and stroke. Internal carotid artery injury may also occur after misguided needle placement, particularly far posteriorly or medially, resulting in carotid cavernous fistula. Anatomical variations of the foramen ovale can predispose those complications. CASE DESCRIPTION: A young woman diagnosed with trigeminal neuralgia during 11 years was submitted to a balloon rhizotomy by percutaneous approach to the trigeminal ganglion, with severe intraoperative bleeding...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28456012/neuregulin-1-positively-modulates-glial-response-and-improves-neurological-recovery-following-traumatic-spinal-cord-injury
#17
Arsalan Alizadeh, Scott M Dyck, Hardeep Kataria, Ghazaleh M Shahriary, Dung H Nguyen, Kallivalappil T Santhosh, Soheila Karimi-Abdolrezaee
Spinal cord injury (SCI) results in glial activation and neuroinflammation, which play pivotal roles in the secondary injury mechanisms with both pro- and antiregeneration effects. Presently, little is known about the endogenous molecular mechanisms that regulate glial functions in the injured spinal cord. We previously reported that the expression of neuregulin-1 (Nrg-1) is acutely and chronically declined following traumatic SCI. Here, we investigated the potential ramifications of Nrg-1 dysregulation on glial and immune cell reactivity following SCI...
April 29, 2017: Glia
https://www.readbyqxmd.com/read/28455199/upper-body-compression-garment-physiological-effects-while-cycling-in-a-hot-environment
#18
Iker Leoz-Abaurrea, Roberto Aguado-Jiménez
OBJECTIVE: The purpose of the present study was to investigate the effects of an upper body compression garment (UBCG) on physiologic and perceptual responses while cycling in a hot environment. METHODS: Twenty recreational road cyclists were pair-matched for age, anthropometric data, and fitness level (V̇O2max) and randomly assigned to a control (CON) group (n=10) of cyclists who wore a conventional t-shirt or to a group (n=10) of cyclists who wore UBCG. Test session consisted of cycling at a fixed load (~50% V̇O2max) for 30 minutes at an ambient temperature of ~40ºC (39...
April 25, 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28453954/local-delivery-of-chondroitinase-abc-with-or-without-stromal-cell-derived-factor-1%C3%AE-promotes-functional-repair-in-the-injured-rat-spinal-cord
#19
Malgosia M Pakulska, Charles H Tator, Molly S Shoichet
Traumatic spinal cord injury (SCI) is a devastating event for which functional recovery remains elusive. Due to the complex nature of SCI pathology, a combination treatment strategy will likely be required for success. We hypothesized that tissue and functional repair would be achieved in a rat model of impact-compression SCI by combining degradation of the glial scar, using chondroitinase ABC (ChABC), with recruitment of endogenous neural precursor cells (NPCs), using stromal cell-derived factor 1α (SDF)...
April 18, 2017: Biomaterials
https://www.readbyqxmd.com/read/28451499/iatrogenic-spinal-cord-injury-resulting-from-cervical-spine-surgery
#20
Alan H Daniels, Robert A Hart, Alan S Hilibrand, David E Fish, Jeffrey C Wang, Elizabeth L Lord, Zorica Buser, P Justin Tortolani, D Alex Stroh, Ahmad Nassr, Bradford L Currier, Arjun S Sebastian, Paul M Arnold, Michael G Fehlings, Thomas E Mroz, K Daniel Riew
STUDY DESIGN: Retrospective cohort study of prospectively collected data. OBJECTIVE: To examine the incidence of iatrogenic spinal cord injury following elective cervical spine surgery. METHODS: A retrospective multicenter case series study involving 21 high-volume surgical centers from the AOSpine North America Clinical Research Network was conducted. Medical records for 17 625 patients who received cervical spine surgery (levels from C2 to C7) between January 1, 2005, and December 31, 2011, were reviewed to identify occurrence of iatrogenic spinal cord injury...
April 2017: Global Spine Journal
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