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https://www.readbyqxmd.com/read/29791614/correlation-between-the-voice-handicap-and-swallowing-quality-of-life-in-patients-with-laryngeal-cancer-submitted-to-chemoradiotherapy
#1
Maria Eduarda da Rosa, Cláudia Tiemi Mituuti, Ana Carolina de Assis Moura Ghirardi
Purpose To verify the correlation between the voice handicap and swallowing quality of life in individuals submitted to chemoradiotherapy for laryngeal cancer treatment. Methods Cross-sectional, observational and quantitative study. Fourteen male individuals diagnosed with laryngeal cancer were submitted to exclusive chemoradiotherapy treatment. The individuals completed the Voice Handicap Index (VHI) and the Swallowing Quality of Life (SWAL-QOL) questionnaires. Data were submitted to descriptive and inferential analysis using Spearman's Correlation Test to verify possible correlations among the scores of these instruments...
2018: CoDAS
https://www.readbyqxmd.com/read/29760737/injection-laryngoplasty-using-autologous-fat-enriched-with-adipose-derived-regenerative-stem-cells-a-safe-therapeutic-option-for-the-functional-reconstruction-of-the-glottal-gap-after-unilateral-vocal-fold-paralysis
#2
José M Lasso, Daniel Poletti, Batolomé Scola, Pedro Gómez-Vilda, Ana I García-Martín, María Eugenia Fernández-Santos
Background: Paralysis of one vocal fold leads to glottal gap and vocal fold insufficiency that has significant impact upon a patient's quality of life. Fillers have been tested to perform intracordal injections, but they do not provide perdurable results. Early data suggest that enriching fat grafts with adipose-derived regenerative cells (ADRCs) promote angiogenesis and modulate the immune response, improving graft survival. The aim of this study is to propose ADRC-enriched adipose tissue grafts as effective filler for the paralyzed vocal fold to use it for functional reconstruction of the glottal gap...
2018: Stem Cells International
https://www.readbyqxmd.com/read/29756480/tracheoesophageal-prosthesis-use-is-associated-with-improved-overall-quality-of-life-in-veterans-with-laryngeal-cancer
#3
Ramya S Patel, Tiffany Mohr, Christine Hartman, Carol Stach, Andrew G Sikora, Jose P Zevallos, Vlad C Sandulache
OBJECTIVES: Veterans have an increased risk of laryngeal cancer, yet their oncologic and functional outcomes remain understudied. We sought to determine the longitudinal impact of tracheoesophageal puncture and voice prosthesis on quality-of-life measures in veterans following total laryngectomy (TL). METHODS: We performed a cross-sectional analysis of TL patients (n = 68) treated at the Michael E. DeBakey Veterans Affairs Medical Center using the Voice Handicap Index (VHI), MD Anderson Dysphagia Index (MDADI), and University of Washington Quality of Life Index (UW-QOL)...
May 1, 2018: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/29738415/efficacy-of-injecting-platelet-concentrate-combined-with-hyaluronic-acid-for-the-treatment-of-vulvovaginal-atrophy-in-postmenopausal-women-with-history-of-breast-cancer-a-phase-2-pilot-study
#4
Barbara Hersant, Mounia SidAhmed-Mezi, Yazid Belkacemi, Franklin Darmon, Sylvie Bastuji-Garin, Gabrielle Werkoff, Romain Bosc, Jeremy Niddam, Oana Hermeziu, Simone La Padula, Jean Paul Meningaud
OBJECTIVE: Approximately 50% to 70% of breast cancer survivors are affected by one or more symptoms of vulvovaginal atrophy (VVA). For those who cannot take hormone therapy, autologous platelet-rich plasma combined with hyaluronic acid (A-PRP-HA) may provide a new alternative therapy for the treatment of VVA in postmenopausal women with history of breast cancer. METHODS: We enrolled 20 postmenopausal breast cancers survivors with VVA and a score of <15 on the Gloria Bachman Vaginal Health Index (VHI) comprised of five items including: vaginal pH, elasticity, fluid volume (secretions), epithelial integrity, and moisture...
May 7, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29730784/voice-quality-preservation-in-thyroid-surgery-with-neuromonitoring
#5
Beata Wojtczak, Krzysztof Sutkowski, Krzysztof Kaliszewski, Zdzisław Forkasiewicz, Bartłomiej Knychalski, Michał Aporowicz, Marek Bolanowski, Marcin Barczyński
PURPOSE: Voice problems are common after thyroidectomy. The aim of this study was to assess the voice related quality of life after thyroidectomy with neuromonitoring. The sociodemographic and treatment factors influencing the quality of voice after the operation were investigated. METHODS: A total of 40 patients after thyroidectomy with neuromonitoring were enrolled into the study. The voice outcome was analyzed pre and postoperatively by two validated self-assessment questionnaires: Voice Handicap Index and Voice-Related Quality of Life survey...
May 5, 2018: Endocrine
https://www.readbyqxmd.com/read/29728930/the-prevalence-of-dysphonia-and-dysphagia-in-patients-affected-by-immunomediated-diseases-and-the-role-of-psychometric-tests
#6
J Galli, M R Marchese, C De Canio, M Di Salvo, I Olivieri, L Santandrea, G Paludetti
This cross-sectional investigation examined the prevalence and severity of dysphonia, globus pharyngeus, and dysphagia in patients affected by immunomediated (IM) diseases. Seventy subjects were administered the Voice Handicap Index (VHI) (scale 0-4), Glasgow-Edinburgh Throat Scale (GETS) (scale from 0 to 7) for globus pharyngeus assessment, and modified Swallowing Outcomes After Revised Laryngectomy (SOAL) (scale 0, 1, 2) to test swallowing symptoms. VHI: the mean percentage of answers with a score greater than 1 (corresponding to a frequency of situation's occurrence "sometimes," "almost always," or "always") was 25...
May 5, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29716720/clinical-experience-with-patients-with-spasmodic-dysphonia-and-primary-meige-syndrome
#7
María Fernanda Pedrero-Escalas, Isabel García-López, Susana Santiago-Pérez, Francisco Vivancos, Javier Gavilán
INTRODUCTION: Meige syndrome (MS) is part of the group of segmental cranial dystonias, which affect more than two cranial muscle groups. Specifically, blepharospasm is associated with another cranial dystonia (oromandibular, cervical or laryngeal). The aim of this paper was to report our experience in patients with spasmodic dysphonia (SD) associated with primary MS. MATERIAL AND METHODS: A retrospective study involving 8 patients between May 2010 and June 2015...
April 28, 2018: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/29699833/a-novel-voxel-based-homogeneity-index-rationale-and-clinical-implications-for-whole-brain-radiation-therapy
#8
Alexander Henry Thieme, Carmen Stromberger, Pirus Ghadjar, Sophie K Piper, Volker Budach
PURPOSE OR OBJECTIVE: A homogeneity index (HI) measures the uniformity of a dose distribution within a given target volume. Traditional HIs only use a limited number of dose-volume histogram data-points for calculation. A voxel-based homogeneity index (VHI) is proposed which utilizes the entire information of the three-dimensional dose distribution. We compared the VHI with existing HIs and analyzed if VHI results were associated with treatment outcomes in patients who underwent therapeutic WBRT...
April 23, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29687184/aerodynamic-findings-and-voice-handicap-index-in-parkinson-s-disease
#9
Sergio Motta, Ugo Cesari, Mariano Paternoster, Giovanni Motta, Giuseppe Orefice
OBJECTIVE: To verify possible relations between vocal disability and aerodynamic measures in selected Parkinson's disease (PD) patients with low/moderate-grade dysphonia. METHODS: Fifteen idiopathic dysphonic PD male patients were examined and compared with 15 euphonic subjects. Testing included the following measures: Voice Handicap Index (VHI), maximum phonation time (MPT), mean estimated subglottal pressure (MESGP), mean sound pressure level (MSPL), mean phonatory power (MPP), mean phonatory efficiency (MPE) and mean phonatory resistance (MPR)...
April 23, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29678440/office-based-autologous-fat-injection-laryngoplasty-for-glottic-insufficiency-in-patients-under-50-years-old
#10
Hao-Chun Hu, Yi-Ting Hung, Shu-Yi Lin, Tao-Hsin Tung, Shyue-Yih Chang
OBJECTIVE: We sought to determine the outcomes of office-based autologous fat injection laryngoplasty in the treatment of patients under 50 years old with glottic insufficiency but without neurological problems or acquired organic lesions in the vocal fold. METHODS: We conducted a retrospective chart review of consecutive patients under 50 years of age who underwent office-based autologous fat injection laryngoplasty for glottic insufficiency. None of the patients presented neurological problems or acquired organic lesions in the vocal fold...
April 17, 2018: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29626250/effect-of-voice-therapy-on-vocal-fold-polyp-treatment
#11
Mustafa Sahin, Sercan Gode, Murat Dogan, Tayfun Kirazli, Fatih Ogut
PURPOSE: To investigate the role of voice therapy (VT) and factors that may affect the response to VT in the treatment of vocal fold polyps, especially as a complement to phonosurgery. METHODS: Retrospective review of patients with vocal fold polyp undergoing surgery and/or VT in a tertiary medical center. The demographic data, phoniatric history, videolaryngostroboscopic findings, polyp characteristics, VHI-10 and GRB scores, and voice analysis data were recorded before and after the treatment...
June 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29624876/very-long-term-voice-handicap-index-voice-outcomes-after-montgomery-thyroplasty-a-cross-sectional-study
#12
G Desuter, E Zapater, S van der Vorst, S Henrard, J T van Lith-Bijl, P P van Benthem, E V Sjögren
OBJECTIVE: The aim of this multi-centric cross-sectional study was to examine the permanency of Montgomery Thyroplasty (MTIS) results from a patient's perspective. DESIGN: The study consisted of collecting Voice Handicap Index (VHI-30) questionnaires from patients who had been previously been operated with MTIS between 2 and 12 years before. Very long term (>2 years) post-operative data were compared to the previously acquired pre-operative and early post-operative VHI results...
April 6, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29621392/life-experience-of-patients-with-unilateral-vocal-fold-paralysis
#13
David O Francis, Ariel E Sherman, Kristen L Hovis, Kemberlee Bonnet, David Schlundt, C Gaelyn Garrett, Louise Davies
Importance: Clinicians and patients benefit when they have a clear understanding of how medical conditions influence patients' life experiences. Patients' perspectives on life with unilateral vocal fold paralysis have not been well described. Objective: To promote patient-centered care by characterizing the patient experiences of living with unilateral vocal fold paralysis. Design, Setting, and Participants: This study used mixed methods: surveys using the voice and dysphagia handicap indexes (VHI and DHI) and semistructured interviews with adults with unilateral vocal cord paralysis recruited from a tertiary voice center...
April 5, 2018: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29583016/preliminary-study-of-novafon-local-vibration-voice-therapy-for-dysphonia-treatment
#14
Ben Barsties V Latoszek
BACKGROUND: The objective of this study was to explore the effectiveness of a five-week Novafon local vibration voice therapy (NLVVT) program for dysphonia treatment. METHODS: Eleven dysphonic subjects participated in this specific program. RESULTS: Treatment effects were assessed during (i.e. weekly) and after NLVVT. Large and significant treatment effects were revealed in acoustics (i.e. spectrography), and multiparametric indices (i.e. Acoustic Voice Quality Index (AVQI), and Dysphonia Severity Index (DSI)) during and after NLVVT (all p values < ...
March 27, 2018: Logopedics, Phoniatrics, Vocology
https://www.readbyqxmd.com/read/29582172/gender-differences-in-the-presentation-of-dysphonia-related-to-laryngopharyngeal-reflux-disease-a-case-control-study
#15
Jérôme R Lechien, Kathy Huet, Mohamad Khalife, Anne-Françoise Fourneau, Camille Finck, Véronique Delvaux, Myriam Piccaluga, Bernard Harmegnies, Sven Saussez
OBJECTIVE: To investigate the voice quality impairments in patients with laryngopharyngeal reflux (LPR) according to the gender. DESIGN: Controlled multi-center study. MATERIALS AND METHODS: 80 LPR patients (40 males and 40 females) with reflux finding score (RFS) > 7 and reflux symptom index (RSI) > 13 were included and clinically compared according to gender. To be considered as LPR patients, subjects responded to an empiric therapeutic trial based on pantoprazole intake and diet recommendations for 3 months or had positive pH/Impedance metry...
March 26, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29573435/comparison-of-cricothyroid-approximation-and-glottoplasty-for-surgical-voice-feminization-in-male-to-female-transsexuals
#16
Elena Mora, Ignacio Cobeta, Antonio Becerra, Maria Jesús Lucio
OBJECTIVE: To compare voice feminization and quality of life (QoL) of Male-to-Female Transsexuals (MtF Ts) after cricothyroid approximation (CTA) or glottoplasty (GL). STUDY DESIGN: Retrospective study. METHODS: Fifty-three MtF Ts were studied between 2007 and 2016. Voice assessment was based on fundamental frequency (F0 ), perceptual rating on GBRAS Hirano scale (Grade, Breathiness, Roughness, Asthenia, Strain), QoL related to voice on the Voice Handicap Index-10 Spanish validated version (VHI-10 Sv) and self-perceived femininity of the voice (SpFv), and overall satisfaction with the surgical technique (Sst) on a visual analogue scale (VAS)...
March 24, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29549900/long-term-quality-of-life-and-psycho-social-outcomes-after-oropharyngeal-cancer-surgery-and-radial-forearm-free-flap-reconstruction-a-gettec-prospective-multicentric-study
#17
Alexandre Bozec, Pierre Demez, Jocelyn Gal, Emmanuel Chamorey, Marie-Yolande Louis, David Blanchard, Dominique De Raucourt, Jean-Claude Merol, Esteban Brenet, Olivier Dassonville, Gilles Poissonnet, José Santini, Frédéric Peyrade, Karen Benezery, Maria Lesnik, Etienne Berta, Pierre Ransy, Emmanuel Babin
OBJECTIVE: To assess long-term quality of life (QoL) and psycho-social outcomes, and to determine their predictive factors after oropharyngeal cancer (OPC) surgery and radial forearm free-flap (RFFF) reconstruction. METHODS: Patients who had undergone OPC surgery and RFFF reconstruction who were still alive and disease-free at least 1 year after surgery were enrolled in this prospective multicentric study. Patients completed the European Organization for Research and Treatment of Cancer (EORTC) Core (QLQ-C30) and Head and Neck Cancer (QLQ-H&N35) QoL questionnaires, the Voice Handicap Index (VHI-10) questionnaire and the Hospital Anxiety and Depression Scale (HADS)...
March 2018: Surgical Oncology
https://www.readbyqxmd.com/read/29538494/voice-deviation-dysphonia-risk-screening-and-quality-of-life-in-individuals-with-various-laryngeal-diagnoses
#18
Katia Nemr, Ariane Cota, Domingos Tsuji, Marcia Simões-Zenari
OBJECTIVES: To characterize the voice quality of individuals with dysphonia and to investigate possible correlations between the degree of voice deviation (D) and scores on the Dysphonia Risk Screening Protocol-General (DRSP), the Voice-Related Quality of Life (V-RQOL) measure and the Voice Handicap Index, short version (VHI-10). METHODS: The sample included 200 individuals with dysphonia. Following laryngoscopy, the participants completed the DRSP, the V-RQOL measure, and the VHI-10; subsequently, voice samples were recorded for auditory-perceptual and acoustic analyses...
March 12, 2018: Clinics
https://www.readbyqxmd.com/read/29522512/4cin-a-computational-pipeline-for-3d-genome-modeling-and-virtual-hi-c-analyses-from-4c-data
#19
Ibai Irastorza-Azcarate, Rafael D Acemel, Juan J Tena, Ignacio Maeso, José Luis Gómez-Skarmeta, Damien P Devos
The use of 3C-based methods has revealed the importance of the 3D organization of the chromatin for key aspects of genome biology. However, the different caveats of the variants of 3C techniques have limited their scope and the range of scientific fields that could benefit from these approaches. To address these limitations, we present 4Cin, a method to generate 3D models and derive virtual Hi-C (vHi-C) heat maps of genomic loci based on 4C-seq or any kind of 4C-seq-like data, such as those derived from NG Capture-C...
March 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/29487993/ablative-dual-phase-erbium-yag-laser-treatment-of-atrophy-related-vaginal-symptoms-in-post-menopausal-breast-cancer-survivors-omitting-hormonal-treatment
#20
A R Mothes, M Runnebaum, I B Runnebaum
PURPOSE: First evaluation of dual-phase vaginal Er:YAG laser to omit hormonal treatment for atrophy-related symptoms in post-menopausal breast cancer survivors following prolapse surgery. METHODS: Patients with a history of breast cancer at the time of surgery for pelvic organ prolapse were offered non-hormonal vaginal Er:YAG laser treatment when complaining of atrophy-related genitourinary syndrome of menopause. A single 10-min course of dual-phase protocol of pulsed Er:YAG laser (2940 nm, fractional ablative and thermal mode, fluence according to tissue thickness)...
May 2018: Journal of Cancer Research and Clinical Oncology
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