Marzieh Akhlaghpour, Emery Haley, Laura Parnell, Natalie Luke, Mohit Mathur, Richard A Festa, Michael Percaccio, Jesus Magallon, Mariana Remedios-Chan, Alain Rosas, Jimin Wang, Yan Jiang, Lori Anderson, David Baunoch
BACKGROUND: Current diagnoses of urinary tract infection (UTI) by standard urine culture (SUC) has significant limitations in sensitivity, especially for fastidious organisms, and the ability to identify organisms in polymicrobial infections. The significant rate of both SUC "negative" or "mixed flora/contamination" results in UTI cases and the high prevalence of asymptomatic bacteriuria indicate the need for an accurate diagnostic test to help identify true UTI cases. This study aimed to determine if infection-associated urinary biomarkers can differentiate definitive UTI cases from non-UTI controls...
January 31, 2024: BMC Infectious Diseases