keyword
https://read.qxmd.com/read/38446149/role-of-preexisting-right-ventricular-remodeling-in-symptoms-and-prognosis-after-transcatheter-tricuspid-valve-repair
#21
JOURNAL ARTICLE
Marc-André Ehrenfels, Caroline Fretter, Jennifer von Stein, Maria Isabel Körber, Hendrik Wienemann, Stephan Baldus, Roman Pfister, Christos Iliadis
BACKGROUND: Severe tricuspid regurgitation (TR) is associated with chronic volume overload and right ventricular remodeling (RVR). Transcatheter tricuspid valve repair (TTVr) reduces TR and can improve quality of life (QoL), but the role of preprocedural RVR on TTVr outcomes remains unclear. AIMS: To investigate the role of RVR on outcomes after TTVr for severe TR. METHODS: Consecutive patients undergoing TTVr (61% edge-to-edge vs. 39% direct annuloplasty) for severe TR were retrospectively compared by preexisting RVR which was defined as dilation of RV mid-level diameter (> 35 mm) according to guidelines...
March 6, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38441886/atrial-secondary-tricuspid-regurgitation-pathophysiology-definition-diagnosis-and-treatment
#22
JOURNAL ARTICLE
Denisa Muraru, Luigi P Badano, Rebecca T Hahn, Roberto M Lang, Victoria Delgado, Nina C Wunderlich, Erwan Donal, Maurizio Taramasso, Alison Duncan, Philipp Lurz, Tom De Potter, José L Zamorano Gómez, Jeroen J Bax, Ralph Stephan von Bardeleben, Maurice Enriquez-Sarano, Francesco Maisano, Fabien Praz, Marta Sitges
Atrial secondary tricuspid regurgitation (A-STR) is a distinct phenotype of secondary tricuspid regurgitation with predominant dilation of the right atrium and normal right and left ventricular function. Atrial secondary tricuspid regurgitation occurs most commonly in elderly women with atrial fibrillation and in heart failure with preserved ejection fraction in sinus rhythm. In A-STR, the main mechanism of leaflet malcoaptation is related to the presence of a significant dilation of the tricuspid annulus secondary to right atrial enlargement...
March 5, 2024: European Heart Journal
https://read.qxmd.com/read/38439997/cor-triatriatum-dexter-with-a-sinus-venosus-atrial-septal-defect-in-a-50-year-old-woman-a-case-report
#23
Hasan Kazma, Malak Fakih, Ali Raad, Aalaa Saleh, Malek Mohammed
The diagnosis of atrial septal defect (ASD) may be delayed until adulthood or even later in life as it is a well-tolerated congenital heart disease. If patients are not examined and investigated well in childhood, the diagnosis may be delayed until later in adulthood when patients present with palpitations and sometimes dyspnea due to the right chambers dilatation from right ventricular volume overload. In this report, we present a case of a 50-year-old female patient with symptoms of heart failure and atrial fibrillation who was found to have dilated right cardiac chambers, dilated pulmonary artery, severe tricuspid regurgitation, pulmonary hypertension, and a pulmonary-to-systemic flow ratio (Qp/Qs) of more than 1...
February 2024: Curēus
https://read.qxmd.com/read/38437953/effects-of-tricuspid-transcatheter-edge-to-edge-repair-on-tricuspid-annulus-diameter-data-from-the-trivalve-registry
#24
JOURNAL ARTICLE
Giulio Russo, Rebecca T Hahn, Hannes Alessandrini, Martin Andreas, Luigi P Badano, Daniel Braun, Kim A Connelly, Paolo Denti, Rodrigo Estevez-Loureiro, Neil Fam, Mara Gavazzoni, Joerg Hausleiter, Dominique Himbert, Daniel Kalbacher, Azeem Latib, Edith Lubos, Sebastian Ludwig, Philipp Lurz, Vanessa Monivas, Georg Nickenig, Daniela Pedicino, Giovanni Pedrazzini, Alberto Pozzoli, Fabien Praz, Joseph Rodes-Cabau, Karl-Philipp Rommel, Joachim Schofer, Horst Sievert, Gilbert Tang, Holger Thiele, Matthias Unterhuber, Ralph Stephan von Bardeleben, John Webb, Stephan Windecker, Martin Leon, Francesco Maisano, Maurizio Taramasso
AIMS: T-TEER is an effective therapy for the treatment of tricuspid regurgitation (TR). However, the effects of leaflets clipping on tricuspid valve annulus (TA) have not been investigated in detail. The aim of this study is to investigate the effects of tricuspid transcatheter edge-to-edge repair (T-TEER) on TA diameter. METHODS AND RESULTS: The TriValve registry (Transcatheter Tricuspid Valve Therapies, NCT03416166) collected 556 patients from 22 European and North American centres undergoing transcatheter tricuspid valve interventions from 2016 to 2022...
March 2, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38436690/-conservative-treatment-of-valvular-heart-disease-in-adults
#25
REVIEW
Johannes Kirchner, Tanja K Rudolph
Currently, there is no specific medication approved for the treatment of valvular heart disease per se. Except for secondary mitral valve insufficiency and tricuspid valve insufficiency in pulmonary hypertension, drug therapy for higher-grade valvular heart disease is limited to diuretic therapy for symptom control. Conservative therapy for comorbidities and potential heart failure can be beneficial regardless of the specific valve lesion. In cases of aortic valve stenosis or insufficiency, controlling arterial hypertension is important...
March 4, 2024: Inn Med (Heidelb)
https://read.qxmd.com/read/38436368/early-outcomes-of-transapical-mitral-valve-implantation-versus-surgical-replacement-in-matched-elderly-patients-at-intermediate-surgical-risk
#26
JOURNAL ARTICLE
Johannes A Ziegelmueller, Melchior Burri, Andreas Stein, Peter Tassani-Prell, Markus Krane, Rüdiger Lange, Hendrik Ruge
BACKGROUND: Data comparing transcatheter mitral valve implantation (TMVI) with surgical mitral valve replacement (SMVR) are lacking. AIMS: This study sought to compare the 30-day Valve Academic Research Consortium (VARC)-3 device success of TMVI with that of SMVR. METHODS: Matching protocol combined exact matching (sex, atrial fibrillation, previous surgical aortic valve replacement [SAVR] or coronary artery bypass grafting [CABG]), coarsened exact matching (age) and propensity score matching (body mass index, mitral valve pathology and concomitant tricuspid regurgitation)...
March 4, 2024: EuroIntervention
https://read.qxmd.com/read/38434561/effects-of-percutaneous-closure-of-atrial-septal-defects-via-the-right-internal-jugular-vein
#27
JOURNAL ARTICLE
Ruichen Wang, Maoxun Huang, Yong Wang, Hulin Piao, Cuilin Zhu, Huiying Wu, Kexiang Liu, Tiance Wang
BACKGROUND: Percutaneous atrial septal defect (ASD) closure is the preferred treatment for patients with suitable ASD anatomy. The safety and effectiveness of transcatheter closure have been established. However, reports on transesophageal echocardiography (TEE)-guided percutaneous closure of ASD via the right internal jugular vein (RIJV) are limited. The study aims to discuss the safety and effectiveness of percutaneous trans-jugular vein closure of ASD. METHODS: We conducted a retrospective analysis of patients (n=103) with secondary ASD who underwent surgical treatment in the Department of Cardiovascular Surgery, the Second Hospital of Jilin University between July 2015 to July 2022...
February 15, 2024: Cardiovascular Diagnosis and Therapy
https://read.qxmd.com/read/38433550/a-case-of-carvajal-syndrome-presenting-with-dilated-cardiomyopathy
#28
JOURNAL ARTICLE
Sule Arıcı, Figen Akalın, Bilgen Bilge Geckinli
OBJECTIVES: Carvajal syndrome is a very rare autosomal recessive cardiocutaneous disorder caused by a desmosomal mutation in exon 24 of the desmoplakin gene. It manifests with woolly hair, epidermolytic palmoplantar keratoderma, and arrhythmogenic right ventricular cardiomyopathy. We herein present a patient with heart failure and dilated cardiomyopathy who was diagnosed with Carvajal syndrome because of dermatologic manifestations. CASE PRESENTATION: A seven-year-old girl was referred to our clinic due to decompensated heart failure and clinical deterioration...
March 4, 2024: Cardiology in the Young
https://read.qxmd.com/read/38432770/transcatheter-treatment-of-mitral-valve-regurgitation-in-the-setting-of-concomitant-coronary-or-multivalvular-heart-disease-a-focused-review
#29
REVIEW
Jay Ramsay, Yicheng Tang, Jin Kyung Kim, Antonio H Frangieh
Treatment for mixed valve disease has historically been limited, often surgery being the only option. With the recent advancement of transcatheter therapies, percutaneous approaches are quickly becoming viable therapeutic considerations in inoperable or high-risk patients, also offering the option for a staged or same-session treatment. Guidelines are primarily focused on single-valve disease. However, patients often present with multiple pathologies. This review summarizes the data and literature on transcatheter treatment of patients with mitral regurgitation who concomitantly have aortic stenosis or regurgitation, tricuspid regurgitation, or ischemic cardiomyopathy...
April 2024: Interventional Cardiology Clinics
https://read.qxmd.com/read/38432347/hypoplastic-left-heart-syndrome-with-mitral-stenosis-and-aortic-atresia-echocardiographic-findings-and-early-outcomes
#30
JOURNAL ARTICLE
Hunter C Wilson, Vikram Sood, Jennifer C Romano, Jeffrey D Zampi, Jimmy C Lu, Sunkyung Yu, Ray E Lowery, Kellianne Kleeman, Sowmya Balasubramanian
BACKGROUND: Mitral stenosis/aortic atresia (MS/AA) has been reported as a high-risk variant of hypoplastic left heart syndrome (HLHS), potentially related to ventriculocoronary connections (VCCs) or endocardial fibroelastosis (EFE) and myocardial hypoperfusion. We aimed to identify echocardiographic and clinical factors associated with early death or transplant in this group. METHODS: Patients with HLHS MS/AA treated at our center between 2000 and 2020 were included...
March 1, 2024: Journal of the American Society of Echocardiography
https://read.qxmd.com/read/38430242/concomitant-interventions-in-mitral-valve-surgery-a-european-perspective
#31
JOURNAL ARTICLE
Vinci Naruka, Arian Arjomandi Rad, Jacob Chacko, Guiqing Liu, Jonathan Afoke, Prakash P Punjabi
INTRODUCTION: In recent years, major findings on concomitant procedures and anticoagulation management have occurred in Mitral Valve (MV) surgery. Therefore, we sought to evaluate the current practices in MV interventions across Europe. METHODS: In October 2021, all national cardio-thoracic societies in the European region were identified following an electronic search and sent an online survey of 14 questions to distribute among their member consultant/attending cardiac surgeons...
March 2, 2024: Perfusion
https://read.qxmd.com/read/38430099/right-heart-remodeling-and-outcomes-in-patients-with-tricuspid-regurgitation-a-literature-review-and-meta-analysis
#32
JOURNAL ARTICLE
Sara Bombace, Federico Fortuni, Giacomo Viggiani, Maria Chiara Meucci, Gianluigi Condorelli, Erberto Carluccio, Maximilian von Roeder, Alexander Jobs, Holger Thiele, Giovanni Esposito, Philipp Lurz, Paul A Grayburn, Anna Sannino
BACKGROUND: Functional tricuspid regurgitation (TR) can develop either because of right ventricular (RV) remodeling (ventricular functional TR) and/or right atrial dilation (atrial functional TR). OBJECTIVES: This meta-analysis aimed to investigate the association between right heart remodeling and long-term (>1 year) all-cause mortality in patients with significant TR (at least moderate, ≥2+). METHODS: MEDLINE, ISI Web of Science, and SCOPUS databases were searched...
February 12, 2024: JACC. Cardiovascular Imaging
https://read.qxmd.com/read/38429438/a-tissue-silicone-integrated-simulator-for-right-ventricular-pulsatile-circulation-with-severe-functional-tricuspid-regurgitation
#33
JOURNAL ARTICLE
Jumpei Takada, Hayato Morimura, Kohei Hamada, Yusei Okamoto, Shiho Mineta, Yusuke Tsuboko, Kaoru Hattori, Kiyotaka Iwasaki
There is a great demand for development of a functional tricuspid regurgitation (FTR) model for accelerating development and preclinical study of tricuspid interventional repair devices. This study aimed to develop a severe FTR model by creating a tissue-silicone integrated right ventricular pulsatile circulatory simulator. The simulator incorporates the porcine tricuspid annulus, valve leaflets, chordae tendineae, papillary muscles, and right ventricular wall as one continuous piece of tissue, thereby preserving essential anatomical relationships of the tricuspid valve (TV) complex...
March 1, 2024: Scientific Reports
https://read.qxmd.com/read/38426859/transcatheter-treatment-of-the-tricuspid-valve-current-status-and-perspectives
#34
JOURNAL ARTICLE
Francesco Maisano, Rebecca Hahn, Paul Sorajja, Fabien Praz, Philipp Lurz
Transcatheter tricuspid valve interventions (TTVI) are emerging as alternatives to surgery in high-risk patients with isolated or concomitant tricuspid regurgitation. The development of new minimally invasive solutions potentially more adapted to this largely undertreated population of patients, has fuelled the interest for the tricuspid valve. Growing evidence and new concepts have contributed to revise obsolete and misleading perceptions around the right side of the heart. New definitions, classifications, and a better understanding of the disease pathophysiology and phenotypes, as well as their associated patient journeys have profoundly and durably changed the landscape of tricuspid disease...
March 1, 2024: European Heart Journal
https://read.qxmd.com/read/38426115/editorial-cardiorenal-disease-a-practical-approach
#35
EDITORIAL
Pedro Caravaca-Pérez, Marta Maria Cobo Marcos, Rafael De La Espriella
No abstract text is available yet for this article.
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38421268/running-on-empty-factors-underpinning-impaired-cardiac-output-reserve-in-heart-failure-with-preserved-ejection-fraction
#36
REVIEW
Paula Sagmeister, Sebastian Rosch, Karl Fengler, Karl-Patrik Kresoja, Tommaso Gori, Holger Thiele, Philipp Lurz, Daniel Burkhoff, Karl-Philipp Rommel
Heart failure with preserved ejection fraction (HFpEF) is frequently attributed etiologically to an underlying left ventricular (LV) diastolic dysfunction, although its pathophysiology is far more complex and can exhibit significant variations among patients. This review endeavours to systematically unravel the pathophysiological heterogeneity by illustrating diverse mechanisms leading to an impaired cardiac output reserve, a central and prevalent haemodynamic abnormality in HFpEF patients. Drawing on previously published findings from our research group, we propose a pathophysiology-guided phenotyping based on the presence of: (1) LV diastolic dysfunction, (2) LV systolic pathologies, (3) arterial stiffness, (4) atrial impairment, (5) right ventricular dysfunction, (6) tricuspid valve regurgitation, and (7) chronotopic incompetence...
February 29, 2024: Experimental Physiology
https://read.qxmd.com/read/38420560/impact-of-tricuspid-annuloplasty-device-shape-and-size-on-valve-mechanics-a-computational-study
#37
JOURNAL ARTICLE
Collin E Haese, Mrudang Mathur, Chien-Yu Lin, Marcin Malinowski, Tomasz A Timek, Manuel K Rausch
BACKGROUND: Tricuspid valve disease significantly affects 1.6 million Americans. The gold standard treatment for tricuspid disease is the implantation of annuloplasty devices. These ring-like devices come in various shapes and sizes. Choices for both shape and size are most often made by surgical intuition rather than scientific rationale. METHODS: To understand the impact of shape and size on valve mechanics and to provide a rational basis for their selection, we used a subject-specific finite element model to conduct a virtual case study...
February 2024: JTCVS open
https://read.qxmd.com/read/38420554/outcomes-of-minimally-invasive-isolated-tricuspid-valve-repair-and-replacement-through-right-mini-thoracotomy
#38
JOURNAL ARTICLE
Ahmed Alnajar, Subhasis Chatterjee, Jacqueline K Olive, Mahmut S Kaymakci, Lauren Gray, Zachary Gray, Joao R Breda, Joseph Lamelas
OBJECTIVE: Isolated tricuspid valve surgery is uncommon and associated with high perioperative morbidity and mortality. We aimed to study the overall outcomes of patients who underwent minimally invasive right thoracotomy tricuspid valve surgery (Mini-TVS), consisting of either tricuspid valve repair (TVre) or replacement (TVR). METHODS: We performed a retrospective analysis of all Mini-TVS procedures (2017-2022), through which we identified isolated tricuspid valve surgeries...
February 2024: JTCVS open
https://read.qxmd.com/read/38418058/clinical-characteristics-and-outcomes-of-patients-screened-for-transcatheter-tricuspid-valve-replacement-the-triact-registry
#39
MULTICENTER STUDY
Daniel Hagemeyer, Anas Merdad, Laura Villegas Sierra, Andrea Ruberti, Faraj Kargoli, Marine Bouchat, Mauro Boiago, Aris Moschovitis, Djeven P Deva, Lukas Stolz, Geraldine Ong, Mark D Peterson, Nicolo Piazza, Maurizio Taramasso, Nicolas Dumonteil, Thomas Modine, Azeem Latib, Fabien Praz, Jörg Hausleiter, Neil P Fam
BACKGROUND: Transcatheter tricuspid valve replacement (TTVR) abolishes tricuspid regurgitation (TR) and has emerged as a definitive treatment for TR. OBJECTIVES: The purpose of this multicenter, observational study was to determine the clinical characteristics and short-term outcomes of patients with TR screened for TTVR. METHODS: Patients underwent TTVR screening at 7 centers on a compassionate-use basis. The primary endpoints were NYHA functional class and TR grade at 30-day follow-up...
February 26, 2024: JACC. Cardiovascular Interventions
https://read.qxmd.com/read/38418057/generalizing-tricuspid-clinical-trial-results-to-the-real-world
#40
EDITORIAL
Mackram F Eleid
No abstract text is available yet for this article.
February 26, 2024: JACC. Cardiovascular Interventions
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