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Tricuspid regurgitation

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https://www.readbyqxmd.com/read/27904114/two-cases-of-proteinase-3-anti-neutrophil-cytoplasmic-antibody-pr3-anca-related-nephritis-in-infectious-endocarditis
#1
Kazuya Hirai, Naoto Miura, Masabumi Yoshino, Kanyu Miyamoto, Hironobu Nobata, Takuhito Nagai, Keisuke Suzuki, Shogo Banno, Hirokazu Imai
We herein report two cases of proteinase 3-anti-neutrophil cytoplasmic antibody (PR3-ANCA)-related nephritis in infectious endocarditis. In both cases, the patients were middle-aged men with proteinuria and hematuria, hypoalbuminemia, decreased kidney function, anemia, elevated C-reactive protein (CRP) levels, and PR3-ANCA positivity. Each had bacteremia, due to Enterococcus faecium in one and Streptococcus bovis in the other. One patient received aortic valve replacement therapy for aortic regurgitation with vegetation, and the other underwent tricuspid valve replacement therapy and closure of a ventricular septic defect to treat tricuspid regurgitation with vegetation...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27890771/echocardiographic-determinants-of-one-year-all-cause-mortality-in-patients-with-chronic-heart-failure-complicated-by-significant-functional-tricuspid-regurgitation
#2
Kai Hu, Dan Liu, Stefan Störk, Sebastian Herrmann, Daniel Oder, Georg Ertl, Wolfram Voelker, Frank Weidemann, Peter Nordbeck
BACKGROUND: Right ventricular (RV) dysfunction plays an important role in chronic heart failure (CHF). We evaluated the echocardiographic determinants of one-year all-cause mortality in CHF patients with clinically relevant functional tricuspid regurgitation (TR). METHODS AND RESULTS: A total of 101 consecutive CHF patients (mean age 74±10 years; 53% male) with moderate/severe functional TR were enrolled. Each patient underwent at least two echocardiography examinations in an interval >6 months...
November 24, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27889914/predictors-of-long-term-mortality-in-older-patients-hospitalized-for-acutely-decompensated-heart-failure-clinical-relevance-of-natriuretic-peptides
#3
Andrea Passantino, Piero Guida, Rocco Lagioia, Enrico Ammirati, Fabrizio Oliva, Maria Frigerio, Domenico Scrutinio
BACKGROUND: Acute heart failure is a common cause of hospitalization among older patients. Optimized risk stratification might improve the outcome for this subgroup of patients. Natriuretic peptides have been used in the diagnosis of heart failure and in evaluating the prognosis of patients hospitalized for heart failure. However, their utility in the elderly is still controversial. OBJECTIVE: To evaluate long-term survival and prognostic factors for elderly patients hospitalized for acutely decompensated heart failure and evaluate the prognostic utility of NT-proBNP...
November 27, 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27885445/limited-ventricular-preload-is-the-main-reason-for-reduced-stress-reserve-after-atrial-baffle-repair
#4
Andreas Eicken, Julia Michel, Alfred Hager, Daniel Tanase, Harald Kaemmerer, Julie Cleuziou, John Hess, Peter Ewert
The atrial baffle repair (ABR) significantly improved the fate of patients with transposition of the great arteries (TGA). However, these patients show impaired exercise tolerance and some present severe decline of systemic ventricular function. Intrinsic myocardial weakness, low heart rate response to exercise and diastolic filling impairment are discussed to be causative. Forty-nine long-term survivors with TGA (median age 23.7 year) after ABR were catheterized with measured oxygen consumption in four conditions (baseline, volume, atrial pacing, dobutamine) and the results were compared to 10 normal controls...
November 24, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27878627/right-ventricular-dysfunction-as-an-echocardiographic-measure-of-acute-rejection-following-heart-transplantation-in-children
#5
Sanjeev Aggarwal, Jennifer Blake, Swati Sehgal
Noninvasive biomarkers of acute allograft rejection (AAR) following orthotopic heart transplantation (OHT) are needed. The aim of this study was to investigate the accuracy of echocardiographic (ECHO) right ventricular (RV) global functional and resistance indices in the detection of AAR. This retrospective chart review included children with biopsy-proven AAR (grade ≥ 2R cellular or CD4 + antibody-mediated rejection) following OHT and an ECHO within 12 h of the biopsy. ECHO measures: (a) ratio of systolic to diastolic duration (S/D), (b) RV myocardial performance index (MPI) and (c) tricuspid regurgitant gradient to RV outflow tract velocity time integral ratio (TRG/VTI), were derived at baseline, during AAR and at two follow-ups...
November 23, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27876287/mid-term-outcomes-of-common-congenital-heart-defects-corrected-through-a-right-subaxillary-thoracotomy
#6
Guoying An, Hongyu Zhang, Shanguang Zheng, Weixin Wang, Liming Ma
OBJECTIVE: To evaluate the mid-term outcomes of the correction of various congenital heart defects through a right subaxillary thoracotomy. METHODS: Between June 2004 and April 2014, all eligible patients were those with a common congenital heart defect corrected via an approach through a right subaxillary thoracotomy. There were 836 patients (male 417, female 419; median age, 3.5 years; median weight 13.6kg) with ventricular septal defect (VSD) closure (523 patients), atrial septal defect (ASD) closure (235 patients), partial atrioventricular canal (PAVC) correction (55 patients), mild tetralogy of Fallot (TOF) (23 patients)...
February 17, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27875728/exercise-induced-pulmonary-hypertension-by-stress-echocardiography-prevalence-and-correlation-with-right-heart-hemodynamics
#7
Deepika Misra, Ante Kendes, Roxana Sulica, Blase Carabello
OBJECTIVES: The aim of this study was to determine the prevalence of exercise-induced pulmonary hypertension (EIPH) in consecutive subjects referred for stress echocardiography for chest pain or shortness of breath and correlate echocardiographic diagnosis of EIPH with hemodynamics at right heart catheterization (RHC). BACKGROUND: Elevated pulmonary pressure can lead to significant morbidity and mortality. EIPH by ehocardiography has been described in patients with connective tissue disease...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27867305/pulmonary-hypertension-in-heart-failure-patients-presenting-at-oauthc-ile-ife-nigeria
#8
Valentine N Amadi, Olufemi E Ajayi, Anthony O Akintomide, Olugbenga O Abiodun, Olaniyi J Bamikole, Michael O Balogun
BACKGROUND: Pulmonary hypertension (PH) is common in heart failure patients. Literature on PH in heart failure is sparse in Nigeria. This study was carried out to determine the prevalence of PH in heart failure patients and ascertain the relationship between left ventricular systolic and diastolic function and the degree of PH. METHODS: A total of 125 heart failure patients had echocardiography done. PH was diagnosed using tricuspid regurgitation jet and pulmonary ejection jet profile...
2016: Clinical Medicine Insights. Cardiology
https://www.readbyqxmd.com/read/27866289/echocardiographic-findings-in-asymptomatic-systemic-lupus-erythematosus-patients
#9
Abdel GaffarA Mohammed, Abdulaziz A Alghamdi, Mohammad A ALjahlan, Ibrahim A Al-Homood
The aim of this study is to use transthoracic echocardiographic (TTE) imaging methods to identify cardiac dysfunction in asymptomatic systemic lupus erythematosus (SLE) patients and to determine the association between echocardiographic findings and serology. This is a prospective cross-sectional study where 50 patients with confirmed diagnoses of SLE were recruited from rheumatology outpatient clinics. Clinical and serological evaluation to confirm the diagnosis of lupus was done in all patients. Fifty SLE patients, 46 (92%) females and 4 (8%) males, were recruited...
November 19, 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27866021/early-pulmonary-arterial-hypertension-immediately-after-closure-of-a-ventricular-or-complete-atrioventricular-septal-defect-beyond-6months-of-age
#10
P Bambul Heck, A Eicken, J Kasnar-Samprec, P Ewert, A Hager
BACKGROUND: Pulmonary arterial hypertension (PAH) is virtually absent after closure of ventricular septal defect (VSD) in the first six months of life. However the prevalence of PAH in patients, who underwent VSD closure later, is not clear. The aim of this study was to analyse the prevalence of PAH after a successful VSD closure after the age of 6months and whether there are risk factors for developing PAH. METHODS: Echocardiographic and right heart catheter data of patients with VSD or complete atrioventricular septal defect, who underwent VSD closure after the age of 6months in our institution between 01/2005 and 06/2014, were retrospectively analyzed...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27862916/transcatheter-closure-of-large-atrial-septal-defects-using-40-mm-amplatzer-septal-occluder-single-group-experience-with-short-and-intermediate-term-follow-up
#11
Bharat Dalvi, Kshitij Sheth, Shreepal Jain, Robin Pinto
OBJECTIVES: To assess feasibility, safety, and efficacy of the use of 40 mm Amplatzer septal occluder (ASO 40) for the closure of large atrial septal defects (ASD). BACKGROUND: There is very little data available on closure of large ASDs with ASO 40. MATERIALS AND METHODS: Case records of patients who underwent ASD closure with ASO 40 between 2002 and 2014 were retrospectively analyzed. All patients had clinical, transthoracic, and transesophageal echocardiographic (TEE) evaluation prior to device closure...
November 12, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27862075/minimally-invasive-implantation-of-heartware-assist-device-and-simultaneous-tricuspid-valve-reconstruction-through-partial-upper-sternotomy
#12
Julia Hillebrand, Andreas Hoffmeier, Tonny Djie Tiong Tjan, Juergen R Sindermann, Christoph Schmidt, Sven Martens, Mirela Scherer
Left ventricular assist device (LVAD) implantation is a well-established therapy to support patients with end-stage heart failure. However, the operative procedure is associated with severe trauma. Third generation LVADs like the HeartWare assist device (HeartWare, Inc., Framingham, MA, USA) are characterized by enhanced technology despite smaller size. These devices offer new minimally invasive surgical options. Tricuspid regurgitation requiring valve repair is frequent in patients with the need for mechanical circulatory support as it is strongly associated with ischemic and nonischemic cardiomyopathy...
November 8, 2016: Artificial Organs
https://www.readbyqxmd.com/read/27860182/from-tricuspid-to-double-orifice-morphology-percutaneous-tricuspid-regurgitation-repair-with-the-mitraclip-device-in-congenitally-corrected-transposition-of-great-arteries
#13
Fabien Picard, Victor-Xavier Tadros, Anita W Asgar
Edge to edge transcatheter mitral valve repair with MitraClip (Abbott Vascular, Menlo Park, CA) is increasing for high-risk surgical patients with significant mitral regurgitation. Patients with congenitally corrected transposition of the great arteries (CCTGA) presenting with tricuspid valve regurgitation of a systemic right ventricle may represent particularly challenging candidates for MitraClip given their anatomy. We report the case of a 67-year-old gentleman with CCTGA and severe tricuspid regurgitation who was referred for MitraClip implantation after heart team consensus...
November 10, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27847162/patient-specific-computational-fluid-dynamics-assessment-of-aortic-hemodynamics-in-a-spectrum-of-aortic-valve-pathologies
#14
Pouya Youssefi, Alberto Gomez, Taigang He, Lisa Anderson, Nick Bunce, Rajan Sharma, C Alberto Figueroa, Marjan Jahangiri
OBJECTIVES: The complexity of aortic disease is not fully exposed by aortic dimensions alone, and morbidity or mortality can occur before intervention thresholds are met. Patient-specific computational fluid dynamics (CFD) were used to assess the effect of different aortic valve morphologies on velocity profiles, flow patterns, helicity, wall shear stress (WSS), and oscillatory shear index (OSI) in the thoracic aorta. METHODS: A total of 45 subjects were divided into 5 groups: volunteers, aortic regurgitation-tricuspid aortic valve (AR-TAV), aortic stenosis-tricuspid aortic valve (AS-TAV), aortic stenosis-bicuspid aortic valve right-left cusp fusion (BAV[RL]), and aortic stenosis-right-non cusp fusion (AS-BAV[RN])...
September 23, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27842947/extracorporeal-support-during-bilateral-sequential-lung-transplantation-in-patients-with-pulmonary-hypertension-risk-factors-and-outcomes
#15
Pranav R Shah, Michael L Boisen, Daniel G Winger, Jose Marquez, Christian A Bermudez, Jay K Bhama, Norihisa Shigemura, Jonathan D'Cuhna, Kathirvel Subramaniam
OBJECTIVE: To identify preoperative predictors of extracorporeal support in patients with pulmonary hypertension (PH) undergoing bilateral sequential lung transplantation (LTx), and to examine outcomes associated with the use of extracorporeal support. DESIGN: Retrospective, observational study. SETTING: Single organ transplantation and tertiary care university medical center. PARTICIPANTS: Adults with PH (preoperative mean pulmonary artery pressure (mPAP)≥25 mmHg) who underwent primary bilateral sequential LTx during 2007 to 2013...
August 18, 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/27837283/restrictive-cardiomyopathy-delayed-occurrence-after-radiotherapy-of-breast-cancer
#16
Barbara Bellmann, Brunilda Alushi, Boris Bigalke, Ulf Landmesser, Andreas J Morguet
A 74-year-old female patient was referred to our department in 2015 with dyspnea, cough and dysphagia. She had been diagnosed with adenocarcinoma of the right breast in 1986 and underwent mastectomy. When she presented with a local recurrence in 1988, she was receiving high-voltage radiation therapy. Transthoracic echocardiography and magnetic resonance imaging revealed tricuspid regurgitation grade III and unclear right heart failure with a massively dilated right atrium. Coronary heart disease could be ruled out...
November 11, 2016: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/27833994/evaluation-of-residual-coarctation-in-infants-with-a-single-right-ventricle-after-stage-i-palliation
#17
Michael P Fundora, Jun Sasaki, Juan-Carlos Muniz, Anthony Rossi, John F Rhodes, Robert L Hannan, Redmond P Burke, Leo Lopez
In infants with a single right ventricle (RV), stage I palliation involves aortic reconstruction, systemic-to-pulmonary shunt placement, and atrial septectomy. Many require re-intervention for residual coarctation of the aorta (CoA). Doppler echocardiography can detect residual CoA in most infants, but its ability to predict severity has not been studied. This study compares gradients from Doppler interrogation to those from cardiac catheterization in infants with residual CoA. We performed a retrospective study of infants after stage I palliation from 2000 to 2014...
November 11, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27829956/bi-luminal-mitral-valve-incidence-clinical-features-associated-anomaly-and-echocardiographic-evaluation
#18
Santosh Kumar Sinha, Vikas Mishra, Karandeep Singh, Mohammad Asif, Mohit Sachan, Ashutosh Kumar, Mukesh Jitendra Jha, Dibbendhu Khanra, Avinash Kumar Singh, Shravan Singh, Mahamdula Razi, Ramesh Thakur, Umeshwar Pandey, Chandra Mohan Varma
OBJECTIVE: The aim of the study was to know the incidence, clinical features, associated anomaly and echocardiographic evaluation of bi-luminal mitral valve (also known as double orifice mitral valve or DOMV) in patients with suspected mitral valve disease, continous murmur or left-to-right shunt. METHODS: Twenty-eight patients with DOMV were diagnosed by transthoracic echocardiography (TTE) in a retrospective review of 52,256 echocardiographic studies in 45,898 patients performed between 2000 and 2015...
December 2016: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27829875/mildly-raised-tricuspid-regurgitant-velocity-2-5-3-0%C3%A2-m-s-in-pregnant-women-with-sickle-cell-disease-is-not-associated-with-poor-obstetric-outcome-an-observational-cross-sectional-study
#19
May C Soh, Srividhya Sankaran, Natali Ya Chung, Catherine Nelson-Piercy, Jo Howard, Sue E Robinson, Eugene Oteng-Ntim
Pulmonary hypertension is associated with 36% mortality in pregnancy, and 6-10% of patients with sickle cell disease have pulmonary hypertension. Tricuspid regurgitant velocity ≥2.5 m/s on echocardiography is a well validated means of screening for pulmonary hypertension in the non-pregnant population. This is a pilot study to determine if this is a useful non-invasive screening test for pulmonary hypertension in pregnancy, and whether raised tricuspid regurgitant velocity ≥2.5 m/s was associated with poor outcomes...
December 2016: Obstetric Medicine
https://www.readbyqxmd.com/read/27818476/congenitally-corrected-transposition-of-the-great-arteries-and-situs-inversus-in-an-octogenarian-with-systemic-right-ventricular-failure
#20
Mikio Shiba, Shigefumi Fukui, Hideo Ohuchi, Jin Ueda, Akihiro Tsuji, Yoshiaki Morita, Aya Miyazaki, Takeshi Ogo, Satoshi Yasuda, Isao Shiraishi, Norifumi Nakanishi
Systemic right ventricular (RV) failure in patients with congenitally corrected transposition of the great arteries (ccTGA), a major cause of mortality in the long-term follow-up, is usually induced by concomitant severe morphologically tricuspid regurgitation (TR) with/without Ebstein's anomaly or progressive conduction tissue disturbances. However, whether or not myocardial fibrosis is a common cause of systemic RV failure in patients with ccTGA remains unclear. Here, we describe an 82-year-old man who had been diagnosed previously as having uncomplicated ccTGA and situs inversus and recently developed systemic RV failure, which was neither associated with severe TR nor advanced conduction tissue abnormalities...
November 4, 2016: International Heart Journal
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