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Old age depression

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https://www.readbyqxmd.com/read/28329850/the-use-of-growth-mixture-modeling-for-studying-resilience-to-major-life-stressors-in-adulthood-and-old-age-lessons-for-class-size-and-identification-and-model-selection
#1
Frank J Infurna, Kevin J Grimm
Objectives: Growth mixture modeling (GMM) combines latent growth curve and mixture modeling approaches and is typically used to identify discrete trajectories following major life stressors (MLS). However, GMM is often applied to data that does not meet the statistical assumptions of the model (e.g., within-class normality) and researchers often do not test additional model constraints (e.g., homogeneity of variance across classes), which can lead to incorrect conclusions regarding the number and nature of the trajectories...
March 8, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28329031/who-take-naps-self-reported-and-objectively-measured-napping-in-very-old-women
#2
Yue Leng, Katie Stone, Sonia Ancoli-Israel, Kenneth Covinsky, Kristine Yaffe
Background: Despite the widespread belief that napping is common among older adults, little is known about the correlates of napping. We examined the prevalence and correlates of self-reported and objectively measured napping among very old women. Methods: We studied 2,675 community-dwelling women (mean age 84.5 ± 3.7 years; range 79-96). Self-reported napping was defined as a report of regular napping for ≥1 hour per day. Individual objective naps were defined as ≥5 consecutive minutes of inactivity as measured by actigraphy and women were characterized as "objective nappers" if they had at least 60 minutes of naps per day...
February 18, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28326218/course-of-neuropsychiatric-symptoms-during-flares-of-systemic-lupus-erythematosus-sle
#3
Gareth Garrett, Nicola Ambrose, Zaib Davids, Dorothea Bindman
We present the case of a seventeen-year-old girl who presents with an interesting course of neuropsychiatric symptoms during several flares of SLE. The patient was diagnosed at the age of thirteen and has had four flares in total. The latter two flares included cutaneous and neuropsychiatric symptoms. The most recent flare occurred when she was aged seventeen. She had cutaneous symptoms which coincided with an episode of hypomania. Her mental state further deteriorated following steroid treatment. She exhibited affective and psychotic symptoms...
2017: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/28324341/beta-amyloid-deposition-in-patients-with-major-depressive-disorder-with-differing-levels-of-treatment-resistance-a-pilot-study
#4
Peng Li, Ing-Tsung Hsiao, Chia-Yih Liu, Chia-Hsiang Chen, She-Yao Huang, Tzu-Chen Yen, Kuan-Yi Wu, Kun-Ju Lin
BACKGROUND: Lack of treatment response in patients with late-life depression is common. The role of brain beta-amyloid (Aβ) deposition in treatment outcome in subjects with late-life depression remains unclear. The present study aimed to investigate brain Aβ deposition in patients with major depressive disorder (MDD) with differing treatment outcomes in vivo using (18)F-florbetapir imaging. This study included 62 MDD patients and 18 healthy control subjects (HCs).We first employed the Maudsley staging method (MSM) to categorize MDD patients into two groups according to treatment response: mild treatment resistance (n = 29) and moderate-to-severe treatment resistance (n = 33)...
December 2017: EJNMMI Research
https://www.readbyqxmd.com/read/28323926/psychological-distress-is-more-prevalent-in-fertile-age-and-premenopausal-women-with-pcos-symptoms-15-yr-follow-up
#5
Salla Karjula, Laure Morin-Papunen, Juha Auvinen, Aimo Ruokonen, Katri Puukka, Stephen Franks, Marjo-Riitta Järvelin, Juha S Tapanainen, Jari Jokelainen, Jouko Miettunen, Terhi T Piltonen
Context: Polycystic ovary syndrome (PCOS) is associated with increased psychological distress; obesity and hyperandrogenism being suggested as key promoters. Objectives: To investigate the prevalence of anxiety/depression and their coexistence in women with PCOS/PCOS symptoms at ages 31 and 46. The roles of obesity, hyperandrogenism and awareness of PCOS on psychological distress were also assessed. Design: Population based follow-up. Setting: Northern Finland Birth Cohort 1966 with 15-year follow-up...
February 27, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28322656/identity-processes-among-older-norwegians-living-in-urban-and-rural-areas
#6
Mary H Kalfoss, Gail Low, Liv Halvorsrud
Guided by the Identity Process Theory, we examined whether 424 Norwegians 60+ years of age would attribute their physical and mental functioning to their health (identity assimilation), to aging itself (identity accommodation), or to both (identity balance). We were also interested in the effect of these attribution styles upon depressive symptoms. Secondary data from the 2004 World Health Organization Quality of Life OLD Group Norwegian Field Study were analyzed using General Linear Model Regression and subsequent Path Analyses...
January 1, 2017: Western Journal of Nursing Research
https://www.readbyqxmd.com/read/28316877/progression-of-pro23his-retinopathy-in-a-miniature-swine-model-of-retinitis-pigmentosa
#7
Patrick A Scott, Juan P Fernandez de Castro, Paul J DeMarco, Jason W Ross, Josephat Njoka, Eric Walters, Randall S Prather, Maureen A McCall, Henry J Kaplan
PURPOSE: We characterize the progression of retinopathy in Filial 1 (F1) progeny of a transgenic (Tg) founder miniswine exhibiting severe Pro23His (P23H) retinopathy. METHODS: The F1 TgP23H miniswine progeny were created by crossing TgP23H founder miniswine 53-1 with wild type (WT) inbred miniature swine. Scotopic (rod-driven) and photopic (cone-driven) retinal functions were evaluated in F1 TgP23H and WT littermates using full field electroretinograms (ffERGs) at 1, 2, 3, 6, 9, 12, and 18 months of age, as well as the Tg founder miniswine at 6 years of age...
March 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28306171/barriers-to-hydroxyurea-adherence-and-health-related-quality-of-life-in-adolescents-and-young-adults-with-sickle-cell-disease
#8
Sherif M Badawy, Alexis A Thompson, Frank J Penedo, Jin-Shei Lai, Karen Rychlik, Robert I Liem
OBJECTIVES: To identify barriers to hydroxyurea adherence (negative beliefs, access, and/or recall barriers), and their relationship to adherence rates and health-related quality of life (HRQOL) amongst adolescents and young adults (AYA) with sickle cell disease (SCD). METHODS: A cross-sectional survey was administered to 34 AYAs (12-22 years old) in SCD clinics from January-December 2015. Study measures included Brief Medication Questionnaire, Modified Morisky Adherence Scale 8-items, Visual Analogue scale and Patient Reported Outcomes Measurement Information System...
March 17, 2017: European Journal of Haematology
https://www.readbyqxmd.com/read/28303455/duodenal-cancer-in-a-young-patient-with-peuts-jeghers-syndrome-harboring-an-entire-deletion-of-the-stk11-gene
#9
Satoshi Teramae, Koichi Okamoto, Kumiko Tanaka, Reika Matsumoto, Shinji Kitamura, Tetsuo Kimura, Masahiro Sogabe, Hiroshi Miyamoto, Naoki Muguruma, Yoshimi Bando, Mitsuo Shimada, Tetsuji Takayama
A 21-year-old woman with Peuts-Jeghers syndrome (PJS) was referred to our hospital for gastrointestinal surveillance. She had been diagnosed as having PJS from a young age based on her family history and the presence of mucocutaneous pigmentation on her lips and oral mucosa. Her mother and brother had PJS harboring an entire deletion of the STK11 gene. She had tetralogy of Fallot, atrial tachycardia, sick sinus syndrome, and mental retardation in her past history. Esophagogastroduodenoscopy identified a protruded lesion with a depressed area that occupied the lumen half-circumferentially in the duodenal second portion and also showed a 10-mm protruded lesion on the anterior wall of the lower gastric body...
March 16, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28303410/downregulation-of-myogenic-micrornas-in-sub-chronic-but-not-in-sub-acute-model-of-daunorubicin-induced-cardiomyopathy
#10
Gabriel Doka, Eva Malikova, Kristina Galkova, Giampiero La Rocca, Peter Kruzliak, Mariusz Adamek, Luis Rodrigo, Peter Krenek, Jan Klimas
Cardiac muscle-related microRNAs play important roles in cardiac development and disease by translational silencing of mRNAs, the dominant mechanism of microRNA action. To test whether they could be involved in daunorubicin-associated cardiomyopathy (DACM), we determined expression patterns of myomiRs in two distinct models of DACM. We used 10-12 weeks old male Wistar rats. In the sub-acute model, rats were administered with six doses of daunorubicin (DAU-A, 3 mg/kg, i.p., every 48 h). Rats were sacrificed two days after the last dose...
March 16, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28303060/evaluation-of-the-association-between-locomotive-syndrome-and-depressive-states-a-cross-sectional-study
#11
Tomohiro Saito, Hideaki Watanabe, Ichiro Kikkawa, Katsushi Takeshita
The Japanese Orthopaedic Association has proposed the term "locomotive syndrome" to designate a condition that places a person at high risk for long-term care. However, in daily clinical practice, even when a diagnosis of locomotive syndrome is made, exercise therapy often cannot be successfully performed in some patients owing to their lack of motivation. We speculated that locomotive syndrome and depressive states co-exist in elderly people. The purpose of this study was to determine the presence or absence of depressive states in older patients aged ≥ 65 years who were diagnosed with locomotive syndrome...
February 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/28297597/leptospirosis-and-depression-a-nationwide-cohort-analysis
#12
Chun-Hsiang Chiu, Ying-Chuan Wang, Cheng-Li Lin, Feng-You Lee, Chia-Hung Kao
OBJECTIVE: We conducted a retrospective cohort study to investigate whether leptospirosis is a risk factor for depression. METHOD: From the Taiwan National Health Insurance Research Database between 2000 and 2010, patients with leptospirosis (ICD-9 code 100) who did not have a history of depression (ICD-9-CM codes 296.2, 296.3, 300.4, and 311) before the index date were enrolled (leptospirosis cohort). For each patient with leptospirosis, 1 control without a history of leptospirosis and depression was randomly selected (nonleptospirosis cohort)...
March 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28295893/do-older-adults-with-chronic-low-back-pain-differ-from-younger-adults-in-regards-to-baseline-characteristics-and-prognosis
#13
S Manogharan, A Kongsted, M L Ferreira, M J Hancock
BACKGROUND: Low back pain (LBP) in older adults is poorly understood because the vast majority of the LBP research has focused on the working aged population. The aim of this study was to compare older adults consulting with chronic LBP to middle aged and young adults consulting with chronic LBP, in terms of their baseline characteristics, and pain and disability outcomes over 1 year. METHODS: Data were systematically collected as part of routine care in a secondary care spine clinic...
March 14, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28293918/the-elderly-liver-transplant-recipients-anxiety-depression-fatigue-and-life-satisfaction
#14
Felix Krenzien, Nicco Krezdorn, Mehmet H Morgül, Georg Wiltberger, Georgi Atanasov, Hans-Michael Hau, Andreas Hinz, Moritz Schmelzle, Michael Bartels, Christian Benzing
Introduction Older patients are neglected in clinical trials and are likely to be excluded from liver transplantation (LT). The aim of this study was to assess fatigue, anxiety, depression, and health-related quality of life (HRQoL) in elderly LT recipients. Methods Questionnaires were mailed to patients who underwent LT between 1993 and 2013. Three groups were created: patients ≥ 70, 60 - 69, and < 60 years old. Mental-health status, life satisfaction, and fatigue were assessed using, respectively, the Hospital Anxiety and Depression Scale (HADS), Questions on Life Satisfaction (FLZ-M), and the Multidimensional Fatigue Inventory (MFI-20)...
March 14, 2017: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/28291263/circumcision-does-not-alter-long-term-glucocorticoids-accumulation-or-psychological-effects-associated-with-trauma-and-stressor-related-disorders
#15
E Ullmann, J Licinio, A Barthel, K Petrowski, B Oratovski, T Stalder, C Kirschbaum, S R Bornstein
Male infants and boys through early adolescence can undergo circumcision either for the sake of upholding religious traditions or for medical reasons. According to both, Jewish as well as Islamic tenets, circumcision is a religious rite symbolizing the bond with God. The World Health Organization (WHO), the United Nations Council (UNC) as well as the American Academy of Pediatrics (AAP), and the Centers for Disease Control and Prevention (CDC) strongly recommend circumcision to promote hygiene and prevent disease...
March 14, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28291259/infant-frontal-eeg-asymmetry-in-relation-with-postnatal-maternal-depression-and-parenting-behavior
#16
D J Wen, N N Soe, L W Sim, S Sanmugam, K Kwek, Y-S Chong, P D Gluckman, M J Meaney, A Rifkin-Graboi, A Qiu
Right frontal electroencephalogram (EEG) asymmetry associates with negative affect and depressed mood, which, among children, are predicted by maternal depression and poor parenting. This study examined associations of maternal depression and maternal sensitivity with infant frontal EEG asymmetry based on 111 mother-6-month-infant dyads. There were no significant effects of postnatal maternal depression or maternal sensitivity, or their interaction, on infant EEG frontal asymmetry. However, in a subsample for which the infant spent at least 50% of his/her day time hours with his/her mother, both lower maternal sensitivity and higher maternal depression predicted greater relative right frontal EEG asymmetry...
March 14, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28286548/the-link-between-infant-regulatory-problems-temperament-traits-maternal-depressive-symptoms-and-children-s-psychopathological-symptoms-at-age-three-a-longitudinal-study-in-a-german-at-risk-sample
#17
Anna Sidor, Cristina Fischer, Manfred Cierpka
BACKGROUND: Difficult conditions during childhood can limit an individual's development in many ways. Factors such as being raised in an at-risk family, child temperamental traits or maternal traits can potentially influence a child's later behaviour. The present study investigated the extent of regulatory problems in 6-month-old infants and their link to temperamental traits and impact on externalizing and internalizing problems at 36 months. Moderating effects of maternal distress and maternal depressive symptoms were tested as well...
2017: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/28286214/cognitive-status-in-the-oldest-old-and-centenarians-a-condition-crucial-for-quality-of-life-methodologically-difficult-to-assess
#18
REVIEW
Beatrice Arosio, Rita Ostan, Daniela Mari, Sarah Damanti, Francesco Ronchetti, Sara Arcudi, Maria Scurti, Claudio Franceschi, Daniela Monti
Human life expectancy and the number of the oldest old are rapidly increasing worldwide. Advanced age is the main risk factor for dementia, representing one of the major causes of disability/dependency among older people with a strong impact on their families/caregivers. Centenarians have reached the extreme limits of human life escaping or delaying the major age-related diseases. Thus, these extraordinary individuals embody the best model to answer the crucial question if cognitive decline and dementia are progressive and unavoidable occurrences of increasing age...
March 9, 2017: Mechanisms of Ageing and Development
https://www.readbyqxmd.com/read/28285771/improvement-in-depression-is-associated-with-improvement-in-cognition-in-late-life-psychotic-depression
#19
Lindsay W Victoria, Ellen M Whyte, Meryl A Butters, Barnett S Meyers, George S Alexopoulos, Benoit H Mulsant, Anthony J Rothschild, Samprit Banerjee, Alastair J Flint
OBJECTIVE: To characterize cognitive function at baseline and investigate the relationship between change in cognition, depression, and psychosis after treatment among older adults with major depressive disorder with psychotic features. METHODS: This was a secondary analysis of a double-blind, randomized, controlled treatment trial at inpatient and outpatient settings at four academic health centers on "Young Old" (aged 60-71 years, N = 71) and "Older" (aged 72-86 years, N = 71) participants diagnosed with psychotic depression...
February 9, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28285739/neuropsychiatric-comorbidities-in-adults-with-phenylketonuria-a-retrospective-cohort-study
#20
Deborah A Bilder, Joyce A Kobori, Jessica L Cohen-Pfeffer, Erin M Johnson, Elaina R Jurecki, Mitzie L Grant
Adults with phenylketonuria (PKU) may experience neurologic and psychiatric disorders, including intellectual disability, anxiety, depression, and neurocognitive dysfunction. Identifying the prevalence and prevalence ratios of these conditions will inform clinical treatment. This nested, case-controlled study used International Classification of Diseases, Ninth Revision (ICD-9) codes from the MarketScan® insurance claims databases from 2006 to 2012 and healthcare claims data for US-based employer and government-sponsored health plans...
March 6, 2017: Molecular Genetics and Metabolism
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