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https://www.readbyqxmd.com/read/28098735/optical-coherence-tomography-angiography-of-the-fovea-in-children-born-preterm
#1
Khalil Ghasemi Falavarjani, Nicholas A Iafe, Federico G Velez, Steven D Schwartz, Srinivas R Sadda, David Sarraf, Irena Tsui
PURPOSE: To compare the foveal avascular zone (FAZ) area measured by optical coherence tomography angiography in children who had been born preterm with age-matched controls. METHODS: In this cross-sectional observational comparative case series, 43 eyes of 26 children (28 eyes of 15 former preterm infants and 15 eyes of 11 former term infants) between the ages of 4 and 12 years old were included. Optical coherence tomography angiography with a scan size of 3 × 3 was performed for all eyes...
January 16, 2017: Retina
https://www.readbyqxmd.com/read/28095072/parental-coping-depressive-symptoms-and-children-s-asthma-control-and-school-attendance-in-low-income-racially-and-ethnically-diverse-urban-families
#2
Erin M Rodríguez, Harsha Kumar, Juliana Alba-Suarez, Lisa Sánchez-Johnsen
OBJECTIVE: Low-income urban children of color are at elevated risk for poor asthma control. This cross-sectional study examined associations among parents' coping (primary control, secondary control, and disengagement), parental depressive symptoms, and children's asthma outcomes (asthma control and school attendance) in a predominantly low-income, racially/ethnically diverse sample of families. METHODS: Parents (N = 78; 90% female) of children (33% female; 46% Black; 38% Latino) ages 5 to 17 years old (M = 9...
January 17, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28092295/income-family-context-and-self-regulation-in-5-year-old-children
#3
Mengying Li, Jenna L Riis, Sharon R Ghazarian, Sara B Johnson
OBJECTIVE: Self-regulation (SR) is a core aspect of child development with enduring effects on health and wellbeing across the lifespan. Early childhood poverty may shape SR development. This study examined the cross-sectional relationship among family income, family context, and SR in 5-year-old children. METHODS: A total of 140 five-year-old children and their mothers participated in the study. Children completed a battery of SR tasks; mothers completed questionnaires...
January 12, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28087800/health-care-engagement-among-lgbt-older-adults-the-role-of-depression-diagnosis-and-symptomatology
#4
Chengshi Shiu, Hyun-Jun Kim, Karen Fredriksen-Goldsen
PURPOSE OF THE STUDY: Optimal engagement in health care plays a critical role in the success of disease prevention and treatment, particularly for older adults who are often in greater need of health care services. However, to date, there is still limited knowledge about the relationship between depression and health care engagement among lesbian, gay, bisexual, and transgender (LGBT) older adults. DESIGN AND METHODS: This study utilized data from Aging with Pride: National Health, Aging, Sexuality/Gender Study, from the 2014 survey with 2,450 LGBT adults 50 years old and older...
February 2017: Gerontologist
https://www.readbyqxmd.com/read/28087794/bouncing-back-resilience-and-mastery-among-hiv-positive-older-gay-and-bisexual-men
#5
Charles A Emlet, Chengshi Shiu, Hyun-Jun Kim, Karen Fredriksen-Goldsen
PURPOSE OF THE STUDY: Adults with HIV infection are living into old age. It is critical we investigate positive constructs such as resilience and mastery to determine factors associated with psychological well-being. We examine HIV-related factors, adverse conditions, and psychosocial characteristics that are associated with resilience (the ability to bounce back) and mastery (sense of self-efficacy). DESIGN AND METHODS: We analyzed 2014 data from the longitudinal study Aging with Pride: National Health, Aging, and Sexuality/Gender Study (NHAS), focusing on a subsample of 335 gay and bisexual older men...
February 2017: Gerontologist
https://www.readbyqxmd.com/read/28087201/reduction-in-adolescent-depression-after-contact-with-mental-health-services-a-longitudinal-cohort-study-in-the-uk
#6
Sharon A S Neufeld, Valerie J Dunn, Peter B Jones, Tim J Croudace, Ian M Goodyer
BACKGROUND: Evidence regarding the association between service contact and subsequent mental health in adolescents is scarce, and previous findings are mixed. We aimed to longitudinally assess the extent to which depressive symptoms in adolescents change after contact with mental health services. METHODS: As part of a longitudinal cohort study, between April 28, 2005, and March 17, 2010, we recruited 1238 14-year-old adolescents and their primary caregivers from 18 secondary schools in Cambridgeshire, UK...
January 10, 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/28076836/the-metabolic-syndrome-and-10-year-cognitive-and-functional-decline-in-very-old-men-a-population-based-study
#7
Giovanni Viscogliosi, Chiara Donfrancesco, Luigi Palmieri, Simona Giampaoli
OBJECTIVES: To describe longitudinal relationships of metabolic syndrome (MetS) to cognitive decline and functional disability in a sample of older non-institutionalized men. METHODS: data from 1991 to 2000 of the Italian cohorts of the Finland, Italy, the Netherlands, Elderly (FINE) study, were used. Global cognitive function and functional disability, defined as limitations in mobility, basic (ADLs) and instrumental activities of daily living (IADLs) were screened in 1991 and 2000...
January 3, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28076642/activity-rest-rhythm-of-depressed-adolescents-undergoing-therapy-case-studies
#8
Maria Eugênia Mesquita, Maria Eliza Finazzi, Bruno Gonçalves, Lee Fu-I, Leandro L Duarte, José Ricardo Lopes, José Alberto Del-Porto, Luiz Menna-Barreto
Introduction: Disorders of circadian rhythms have been reported in studies of both depressed children and of depressed adolescents. The aim of this study was to evaluate whether there is a relationship between the 24-hour spectral power (24h SP) of the activity/rest rhythm and the clinical course of depression in adolescents. Methods: Six 14 to 17-year-old adolescents were recruited for the study. They were all suffering from major depressive disorder, according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) criteria, as identified by the Schedule for Affective Disorders and Schizophrenia for School Aged Children: Present and Lifetime Version (K-SADS-PL)...
October 2016: Trends in Psychiatry and Psychotherapy
https://www.readbyqxmd.com/read/28075191/reduction-mammaplasty-improves-levels-of-anxiety-depression-and-body-image-satisfaction-in-patients-with-symptomatic-macromastia-in-the-short-and-long-term
#9
Esther Pérez-Panzano, Ana Gascón-Catalán, Ramón Sousa-Domínguez, Patricia Carrera-Lasfuentes, Javier García-Campayo, Antonio Güemes-Sánchez
OBJECTIVE: To evaluate the psychological consequences (anxiety, depression and body image dissatisfaction) of symptomatic macromastia and the effectiveness of breast reduction surgery in re-establishing the mental health of the patient in the short and long term. METHOD: 119 patients over 18 years old who had been diagnosed with symptomatic macromastia were assessed, before surgery, one month after the operation and one year later. Patients completed the Hospital Anxiety and Depression Scale (HADS) and the Body Image Dissatisfaction subscale of the Eating Disorders Inventory (EDI-2)...
January 11, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28075176/the-adapp-trial-a-two-year-longitudinal-multidisciplinary-intervention-study-for-prostate-cancer-frail-patients-on-androgen-deprivation-associated-to-curative-radiotherapy
#10
Julie Mareschal, Kerstin Weber, Pascale Rigoli, Edmund Biason, Laura Frambati, Carole Gotteland, Thomas Zilli, Claude Pichard, Raymond Miralbell
BACKGROUND: Androgen deprivation (AD) therapy combined to radiotherapy (RT) is a curative therapeutic option for patients with non-metastatic locally advanced or aggressive intermediate prostate cancer (PC), though with a range of nutritional, physical, and psychological side effects. A multidisciplinary care program was created to help frail patients to prevent and manage those side effects. MATERIAL AND METHODS: We conducted a longitudinal interventional study in frail patients, presenting either cardiovascular/pulmonary comorbidities, old age (≥75 years), vulnerability ratings, or balance impairment...
January 11, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28072765/phase-ii-study-of-the-pi3k-inhibitor-bkm120-in-patients-with-advanced-or-recurrent-endometrial-carcinoma-a-stratified-type-i-type-ii-study-from-the-gineco-group
#11
P-E Heudel, M Fabbro, C Roemer-Becuwe, M C Kaminsky, A Arnaud, F Joly, S Roche-Forestier, J Meunier, C Foa, B You, F Priou, Y Tazi, A Floquet, F Selle, D Berton-Rigaud, A Lesoin, E Kalbacher, A Lortholary, L Favier, I Treilleux, I Ray-Coquard
: Backround:Patients with metastatic endometrial carcinoma have a poor prognosis and PIK3CA mutations and amplifications are common in these cancers. This study evaluated the efficacy and safety of the pure PI3K inhibitor BKM120 in advanced or recurrent endometrial carcinoma. METHODS: This phase II, multicentre, single-arm, double strata (histological low grade (LG) or high grade (HG)) open-label study enrolled patients with histologically confirmed advanced or recurrent endometrial carcinoma who had received not more than one prior chemotherapy regimen...
January 10, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28069664/physical-activity-sedentary-behavior-and-symptoms-of-major-depression-in-middle-childhood
#12
Tonje Zahl, Silje Steinsbekk, Lars Wichstrøm
OBJECTIVE: The prospective relation between physical activity and Diagnostic and Statistical Manual of Mental Disorders-defined major depression in middle childhood is unknown, as is the stability of depression. We therefore aimed to (1) determine whether there are reciprocal relations between moderate-to-vigorous physical activity (MVPA) and sedentary behavior, on one hand, and Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition defined symptoms of major depressive disorder, on the other and (2) assess the extent of stability in depressive symptoms from age 6 to 10 years...
January 9, 2017: Pediatrics
https://www.readbyqxmd.com/read/28069523/a-chronic-increase-of-corticosterone-age-dependently-reduces-systemic-dna-damage-from-oxidation-in-rats
#13
Anders Jorgensen, Otto Kalliokoski, Kristin Forsberg, Katrine Breitenstein, Allan Weimann, Trine Henriksen, Jann Hau, Gitta Wörtwein, Henrik Enghusen Poulsen, Martin Balslev Jorgensen
Stress and depression are associated with an acceleration of brain and bodily aging; effects which have been attributed to chronic elevations of glucocorticoids. We tested the hypothesis that a three week administration of stress-associated levels of corticosterone (CORT, the principal rodent glucocorticoid) would increase systemic and CNS DNA and RNA damage from oxidation; a phenomenon known to be centrally involved in the aging process. We also hypothesized that older individuals would be more sensitive to this effect and that the chronic CORT administration would exacerbate age-related memory decline...
January 7, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28064358/incipient-progressive-supranuclear-palsy-is-more-common-than-expected-and-may-comprise-clinicopathological-subtypes-a-forensic-autopsy-series
#14
Koji Yoshida, Yukiko Hata, Koshi Kinoshita, Shutaro Takashima, Kortaro Tanaka, Naoki Nishida
We investigated 998 serial Japanese forensic autopsy cases (0-101 years old, mean age 61.7 ± 21.9), with no case selection, using immunohistochemistry to detect cases with progressive supranuclear palsy (PSP). Twenty-nine cases (mean age 82.3 ± 7.2 years, 11 males, 18 females) fulfilled the National Institute of Neuronal Disorders and Stroke (NINDS)-PSP pathological criteria (2.9% of all cases, 4.6% of cases over 60). All had neuronal and glial inclusions in the basal ganglia and brainstem. However, 13 cases had low tau pathology and were categorized as atypical PSP...
January 7, 2017: Acta Neuropathologica
https://www.readbyqxmd.com/read/28062256/dehydroepiandrosterone-increases-the-number-and-dendrite-maturation-of-doublecortin-cells-in-the-dentate-gyrus-of-middle-age-male-wistar-rats-exposed-to-chronic-mild-stress
#15
J J Herrera-Pérez, L Martínez-Mota, G Jiménez-Rubio, L Ortiz-López, E A Cabrera-Muñoz, N Galindo-Sevilla, E Zambrano, F Hernández-Luis, G B Ramírez-Rodríguez, M Flores-Ramos
Aging increases the vulnerability to stress and risk of developing depression. These changes have been related to a reduction of dehydroepiandrosterone (DHEA) levels, an adrenal steroid with anti-stress effects. Also, adult hippocampal neurogenesis decreases during aging and its alteration or impaired is related to the development of depression. Besides, it has been hypothesized that DHEA increases the formation of new neurons. However, it is unknown whether treatment with DHEA in aging may stimulate the dendrite maturation of newborn neurons and reversing depressive-like signs evoked by chronic stress exposure...
January 4, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28056872/a-limb-girdle-myopathy-phenotype-of-runx2-mutation-in-a-patient-with-cleidocranial-dysplasia-a-case-study-and-literature-review
#16
Sung-Ju Hsueh, Ni-Chung Lee, Shu-Hua Yang, Han-I Lin, Chin-Hsien Lin
BACKGROUND: Cleidocranial dysplasia (CCD) is a rare hereditary disorder that arises from heterozygous loss of function mutations in the runt-related transcription factor 2 (RUNX2) gene. As RUNX2 is mainly expressed in osteoblasts, CCD typically affects the skeletal and dental systems. Few studies have investigated RUNX2 mutation effects on non-skeletal systems. Here, we describe limb-girdle myopathy, an uncommon phenotype of CCD, in a patient with a heterozygous missense mutation (p.R225Q) in the RUNX2 gene...
January 6, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28056357/the-associations-of-adolescents-dating-violence-victimization-well-being-and-engagement-in-risk-behaviors
#17
Joris Van Ouytsel, Koen Ponnet, Michel Walrave
This brief report describes dating violence victimization among adolescents in Flanders, Belgium, and focuses on how dating violence is related to adolescents' well-being and engagement in risk behaviors, such as substance use, sexual behaviors, and engagement in vandalism or fighting. A survey was conducted in Flanders, Belgium among 1187 adolescents (61.3% female, n = 728). A total of 466 respondents between 16 and 22 years old (M = 17.82 years, SD = 0.92) were in a relationship (71.0% female, n = 331), and, therefore, formed the subsample of the present study...
January 2, 2017: Journal of Adolescence
https://www.readbyqxmd.com/read/28054834/long-term-restrictions-in-participation-in-stroke-survivors-under-and-over-70-years-of-age
#18
Joris A de Graaf, Maria L van Mierlo, Marcel W M Post, Wilco P Achterberg, L Jaap Kappelle, Johanna M A Visser-Meily
PURPOSE: This study aims to (1) assess differences in participation restrictions between stroke survivors aged under and over 70 years and (2) identify predictors associated with favorable and unfavorable long-term participation in both age groups. METHODS: Prospective cohort study in which 326 patients were assessed at stroke onset, two months and one year after stroke. The Utrecht Scale for Evaluation of Rehabilitation-Participation (USER-Participation) was used to measure participation restrictions one year after stroke...
January 5, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28053535/atypical-major-depressive-episode-as-initial-presentation-of-intracranial-germinoma-in-a-male-adolescent
#19
Yi-Ting Chen, Kuan-Pin Su, Jane Pei-Chen Chang
A 17-year-old adolescent boy presented with atypical major depressive episode (MDE) without specific focal neurological signs for 6 months. He had a diagnosis of intra-cranial germinoma, and the atypical MDE symptoms subsided after the operation. However, he had a relapse of atypical MDE 7 months after the first surgery. His mood and binge eating symptoms subsided, but intractable body weight gain only partially improved after treatment. When encountering manifestations of depression with atypical features, especially with binge eating symptoms in male children and adolescents, with early onset age, no family history, and prolonged depressive episodes, clinicians should consider not only mood disorders including bipolar spectrum disorders but also organic brain lesions such as intracranial germinoma...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28050181/factors-associated-with-depressive-symptoms-in-young-adults-with-coronary-artery-disease-tehran-heart-center-s-premature-coronary-atherosclerosis-cohort-thc-pac-study
#20
Seyed Hesameddin Abbasi, Seyed Ebrahim Kassaian, Saeed Sadeghian, Abbasali Karimi, Soheil Saadat, Flora Peyvandi, Arash Jalali, Tahereh Davarpasand, Shahin Akhondzadh, Nazila Shahmansouri, Masoumeh Lotfi-Tokaldany, Maryam Amiri Abchouyeh, Farah Ayatollahzade Isfahani, Frits Rosendaal
Objective: Depressed coronary artery disease (CAD) patients may experience a poorer prognosis than non-depressed patients. The aim of this study was to find the associated factors for depressive symptoms in young adults with CAD. Method: This was a cross-sectional study within Tehran Heart Center's Premature Coronary Atherosclerosis Cohort (THC-PAC) study. Young adult CAD patients (men ≤ 45 year-old and women ≤ 55 year-old) were visited from March 2013 to February 2014. Demographic, clinical and laboratory data were collected and all patients were asked to fill in the Beck Depression Inventory II...
October 2016: Iranian Journal of Psychiatry
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