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https://www.readbyqxmd.com/read/28716590/lumbar-muscle-inflammation-alters-spinally-mediated-locomotor-recovery-induced-by-training-in-a-mouse-model-of-complete-spinal-cord-injury
#1
Renaud Jeffrey-Gauthier, Mathieu Piché, Hugues Leblond
Locomotor networks after spinal cord injury (SCI) are shaped by training-activated proprioceptive and cutaneous inputs. Nociception from injured tissues may alter these changes but has largely been overlooked. The objective of the present study was to ascertain whether lumbar muscle inflammation hinders locomotion recovery in a mouse model of complete SCI. Lower limb kinematics during treadmill training was assessed before and after complete SCI at T8 (2, 7, 14, 21 and 28 days post-injury). Locomotor recovery was compared in 4 groups of CD1 mice: control spinal mice; spinal mice with daily locomotor training; spinal mice with lumbar muscle inflammation (Complete Freund's Adjuvant (CFA) injection); and spinal mice with locomotor training and CFA...
July 14, 2017: Neuroscience
https://www.readbyqxmd.com/read/28714853/unveiling-the-development-of-intracranial-injury-using-dynamic-brain-eit-an-evaluation-of-current-reconstruction-algorithms
#2
Haoting Li, Rongqing Chen, Canhua Xu, Benyuan Liu, Mengxing Tang, Lin Yang, Xiuzhen Dong, Feng Fu
Dynamic brain EIT is a promising technique for continuous monitoring the development of cerebral injury. While there are many reconstruction algorithms available to brain EIT, there is still a lack of study to compare their performance in the context of dynamic brain monitoring. To address the problem, we develop a framework for evaluating different current algorithms with their ability to correctly identify small intracranial conductivity changes. Firstly, a simulation 3D head phantom with realistic layered structure and impedance distribution were developed...
July 17, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28714151/resilience-as-a-moderator-of-the-indirect-effects-of-conflict-and-workload-on-job-outcomes-among-nurses
#3
Julie Jean Lanz, Valentina Bruk-Lee
AIM: To examine the relative effects of interpersonal conflict and workload on job outcomes (turnover intentions, burnout, injuries) and examine if resilience moderates the indirect effects of conflict and workload on job outcomes via job-related negative affect. BACKGROUND: There is interest in understanding resilience in the nursing profession. Placing resilience in the context of the Emotion-Centered Model of Occupational Stress (Spector, 1998) is a novel approach to understanding how resilience ameliorates the negative effects of workplace stressors...
July 16, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28713235/connecting-the-brain-to-itself-through-an-emulation
#4
Mijail D Serruya
Pilot clinical trials of human patients implanted with devices that can chronically record and stimulate ensembles of hundreds to thousands of individual neurons offer the possibility of expanding the substrate of cognition. Parallel trains of firing rate activity can be delivered in real-time to an array of intermediate external modules that in turn can trigger parallel trains of stimulation back into the brain. These modules may be built in software, VLSI firmware, or biological tissue as in vitro culture preparations or in vivo ectopic construct organoids...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28712541/mechanical-demands-on-the-lower-back-in-patients-with-non-chronic-low-back-pain-during-a-symmetric-lowering-and-lifting-task
#5
Iman Shojaei, Elizabeth G Salt, Quenten Hooker, Babak Bazrgari
There is limited information in the literature related to the lower back loading in patients with LBP, particularly those with non-chronic LBP. Toward addressing such a research gap, a case-control study was conducted to explore the differences in lower back mechanical loads between a group of females (n=19) with non-chronic, non-specific LBP and a group of asymptomatic females (n=19). The differences in lower back mechanical loads were determined when participants completed one symmetric lowering and lifting of a 4...
July 5, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28709049/idiopathic-spontaneous-pulmonary-torsion-of-the-lingula-a-case-report
#6
Masatoshi Kanayama, Toshihiro Osaki, Natsumasa Nishizawa, Makoto Nakagawa, Tomoko So, Mantaro Kodate
INTRODUCTION: Spontaneous pulmonary torsion is an extremely rare event and is known to occur as a complication of thoracic surgery and traumatic injuries. PRESENTATION OF CASE: An 18-year-old man presented to our hospital with pain in the left back region. Clinical examination, computed tomography and bronchoscopy are crucial for diagnosis of pulmonary torsion. During thoracotomy, the lingula segment was observed to be bent on the head side and turned 180° counterclockwise; subsequently, lingulectomy was performed...
June 29, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28709048/intentional-burn-injury-assessment-of-allegations-of-self-infliction
#7
Juliet Cohen, Jo Pettitt, Emily Wilbourn
This study investigates the question of whether there is evidence that suggests the possibility of self-infliction, or self-infliction by proxy, of burn injury among a group of asylum claimants in the UK who have attributed such injuries to torture, and how such evidence might be assessed. The question arose from the observations of doctors at the UK-based charity Freedom from Torture that increasing numbers of individuals from Sri Lanka who described a history of torture had suffered severe and disfiguring burn injuries from heated metal objects, and the suggestion from asylum decision-makers that in some cases such injuries could have been acquired deliberately by self-infliction or self-infliction by proxy rather than by torture as claimed...
July 5, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28708040/anterior-lumbar-discectomy-and-fusion-for-acute-cauda-equina-syndrome-caused-by-recurrent-disc-prolapse-report-of-3-cases
#8
Kimberly-Anne Tan, Mathew D Sewell, Yma Markmann, Andrew J Clarke, Oliver M Stokes, Daniel Chan
There is a lack of information and consensus regarding the optimal treatment for recurrent disc herniation previously treated by posterior discectomy, and no reports have described an anterior approach for recurrent disc herniation causing cauda equina syndrome (CES). Revision posterior decompression, irrespective of the presence of CES, has been reported to be associated with significantly higher rates of dural tears, hematomas, and iatrogenic nerve root damage. The authors describe treatment and outcomes in 3 consecutive cases of patients who underwent anterior lumbar discectomy and fusion (ALDF) for CES caused by recurrent disc herniations that had been previously treated with posterior discectomy...
July 14, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28706986/liver-preservation-by-aortic-perfusion-alone-compared-with-preservation-by-aortic-perfusion-and-additional-arterial-ex-situ-back-table-perfusion-with-histidine-tryptophan-ketoglutarate-solution-a-prospective-randomized-controlled-multicenter-study
#9
Gerd Otto, Michael Heise, Jochen Thies, Michael Pitton, Jens Schneider, Gernot Kaiser, Peter Neuhaus, Otto Kollmar, Michael Barthels, Josef Geks, Wolf Otto Bechstein, Achim Hellinger, Jürgen Klempnauer, Winfried Padberg, Nils Frühauf, Andre Ebbing, Dietmar Mauer, Astrid Schneider, Robert Kwiecien, Kai Kronfeld
BACKGROUND: Arterial ex situ back-table perfusion (BP) reportedly reduces ischemic-type biliary lesion after liver transplantation. We aimed to verify these findings in a prospective investigation. METHODS: Our prospective, randomized, controlled, multicenter study involved livers retrieved from patients in 2 German regions, and compared the outcomes of standard aortic perfusion to those of aortic perfusion combined with arterial ex situ BP. The primary endpoint was the incidence of ischemic-type biliary lesions over a follow-up of 2 years after liver transplantation, whereas secondary endpoints included 2-year graft survival, initial graft damage as reflected by transaminase levels, and functional biliary parameters at 6 months after transplantation...
July 2017: Transplantation Direct
https://www.readbyqxmd.com/read/28705042/musculoskeletal-injuries-in-gastrointestinal-endoscopists-a-systematic-review
#10
Diana E Yung, Tommaso Banfi, Gastone Ciuti, Alberto Arezzo, Paolo Dario, Anastasios Koulaouzidis
INTRODUCTION: Gastrointestinal(GI) endoscopy forms a significant proportion of clinicians' workloads. However, little attention is given to the ergonomic aspects of endoscopy. This systematic review of musculoskeletal pain and/or injuries in GI endoscopists aims to better understand the types of occupational injuries resulting from endoscopic procedures and associated risk factors. Areas covered: Systematic literature search conducted for articles evaluating prevalence, risk factors and mechanism of musculoskeletal pain and/or injuries related to GI endoscopy...
July 14, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28704245/inciting-events-associated-with-lumbar-facet-joint-pain
#11
Charles A Odonkor, Yian Chen, Peju Adekoya, Bryan J Marascalchi, Hira Chaudhry-Richter, Teresa Tang, Christopher Abruzzese, Berklee K Cohen, Steven P Cohen
BACKGROUND: Low back pain is the leading cause of years lost to disability with approximately 15%-25% of the chronic back pain population suffering from lumbar facet arthropathy. No large-scale study has sought to systematically identify inciting events for lumbar facet arthropathy. The aim of this study is to quantify the proportion of individuals with lumbar facetogenic pain who report a specific precipitating event(s) and to determine if there is a correlation between these events and treatment outcome...
July 10, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28703044/implementation-of-a-safe-patient-handling-program-in-a-multihospital-health-system-from-inception-to-sustainability-successes-over-8-years-and-ongoing-challenges
#12
Christine Olinski, Christine E Norton
Musculoskeletal injuries, especially back injuries, are among the most frequent injuries sustained by direct caregivers who lift, transfer, and reposition patients. These injuries can be debilitating and, for some caregivers, career ending. In the first year following implementation of the safe patient handling program in a multihospital health care system, an 82% reduction in Occupational Health and Safety Administration (OSHA) recordable patient handling injuries was realized, a 94% decrease in days away from work, an 85% reduction in restricted duty days, and an 82% reduction in incurred workers' compensation costs...
July 1, 2017: Workplace Health & Safety
https://www.readbyqxmd.com/read/28702971/history-of-venous-leg-ulcers
#13
S Gianfaldoni, U Wollina, J Lotti, R Gianfaldoni, T Lotti, M G Roccia
To retrieve the history of venous ulcers and of skin lesions in general, we must go back to the appearance of human beings on earth. It is interesting to note that cutaneous injuries evolved parallel to human society. An essential first step in the pathogenesis of ulcers was represented by the transition of the quadruped man to Homo Erectus. This condition was characterized by a greater gravitational pressure on the lower limbs, with consequences on the peripheral venous system. Furthermore, human evolution was characterized by an increased risk of traumatic injuries, secondary to his natural need to create fire and hunt (e...
July 13, 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28702969/bi-layered-collagen-nano-structured-membrane-prototype-collagen-matrix-10826%C3%A2-for-soft-tissue-regeneration-in-rabbits-an-in-vivo-ultra-structural-study-of-the-early-healing-phase
#14
D De Santis, G B Menchini Fabris, J Lotti, C Palumbo, M Ferretti, R Castellani, T Lotti, G Zanotti, F Gelpi, C Covani, P F Nocini
Collagen Matrix (CM) 10826 is a nanostructured bi-layered collagen membrane obtained from type I and III porcine collagen, which in vitro has shown to have the potential to be a substitute and/or stimulant for soft oral tissue regeneration. The objective of this study was to evaluate the in vivo potential and safety of this membrane for soft tissue regeneration in the early stage of wound healing. Two soft tissue wounds (test and control) were created on the back skin of 5 rabbits (female New Zealand White Rabbits specific pathogen free)...
July 13, 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28702921/acl-return-to-sport-guidelines-and-criteria
#15
REVIEW
George J Davies, Eric McCarty, Matthew Provencher, Robert C Manske
PURPOSE OF REVIEW: Because of the epidemiological incidence of anterior cruciate ligament (ACL) injuries, the high reinjury rates that occur when returning back to sports, the actual number of patients that return to the same premorbid level of competition, the high incidence of osteoarthritis at 5-10-year follow-ups, and the effects on the long-term health of the knee and the quality of life for the patient, individualizing the return to sports after ACL reconstruction (ACL-R) is critical...
July 12, 2017: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/28702768/a-prospective-cohort-study-of-the-impact-of-return-to-work-coordinators-in-getting-injured-workers-back-on-the-job
#16
Tyler J Lane, Rebbecca Lilley, Sheilah Hogg-Johnson, Anthony D LaMontagne, Malcolm R Sim, Peter M Smith
Purpose To assess the impact of workplace-based return-to-work (RTW) Coordinators' interpersonal and functional activities on RTW outcomes. Methods Multivariable logistic regression analyses of cross-sectional and longitudinal survey responses of 632 injured workers with at least 10 days of work absence in Victoria, Australia, adjusting for demographic and other workplace factors. Outcome was being back at work for at least 1 month, measured at both baseline and 6 month follow-up survey. Participant responses to stressfulness of Coordinator interactions were dichotomised into good and poor and evaluated as a proxy for Coordinators' interpersonal activities, while having a RTW plan was evaluated as a proxy for functional activities...
July 12, 2017: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/28702699/work-related-musculoskeletal-injuries-amongst-obstetrics-and-gynaecology-trainees-in-east-midland-region-of-the-uk
#17
Kubra Arslan Okuyucu, Yadava Jeve, Angie Doshani
PURPOSE: Work-related musculoskeletal injuries (WRMSI) have been well known amongst obstetrics and gynaecology (O&G) practitioners, but limited data have been reported. Our aim is to determine the prevalence, severity and characteristics of WRMSI amongst O&G trainees. METHODS: A musculoskeletal ergonomic survey was conducted amongst the O&G trainees in the East-Midlands region of United Kingdom (UK). The survey comprised of demographic details, year of training, previous manual handling training, any work-related orthopaedic injury, the type of injury, any treatment received in addition to any sick leave incurred after the injury were also documented...
July 12, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28688639/identifying-preventable-trauma-death-does-autopsy-serve-a-role-in-the-peer-review-process
#18
Dane Scantling, Amanda Teichman, Robert Kucejko, Brendan McCracken, James Eakins, Richard Burns
BACKGROUND: Missing life-threatening injuries is a persistent concern in any trauma program. Autopsy is a tool routinely utilized to determine an otherwise occult cause of death in many fields of medicine. It has been adopted as a required component of the trauma peer review (PR) process by both the American College of Surgeons and the Pennsylvania Trauma Foundation. We hypothesized that autopsy would not identify preventable deaths for augmentation of the PR process. MATERIALS AND METHODS: A retrospective chart review using our institutional trauma registry of all trauma deaths between January 2012 and December 2015 was performed...
July 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28686146/synovial-cysts-of-the-spine-long-term-follow-up-after-surgical-treatment-of-141-cases-in-a-single-center-series-and-comprehensive-literature-review-of-2900-degenerative-spinal-cysts
#19
Markus Bruder, Adriano Cattani, Florian Gessler, Christian Droste, Matthias Setzer, Volker Seifert, Gerhard Marquardt
OBJECTIVE Synovial cysts of the spine are rare lesions, predominantly arising in the lumbar region. Despite their generally benign behavior, they can cause severe symptoms due to compression of neural structures in the spinal canal. Treatment strategies are still a matter of discussion. The authors performed a single-center survey and literature search focusing on long-term results after minimally invasive surgery. METHODS A total of 141 consecutive patients treated for synovial cysts of the lumbar spine between 1997 and 2014 in the authors' department were analyzed...
July 7, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28684013/cervical-spine-alignment-in-helmeted-skiers-and-snowboarders-with-suspected-head-and-neck-injuries-comparison-of-lateral-c-spine-radiographs-before-and-after-helmet-removal-and-implications-for-ski-patrol-transport
#20
Jared Murray, David A Rust
OBJECTIVE: Current protocols for spine immobilization of the injured skier/snowboarder have not been scientifically validated. Observing changes in spine alignment during common rescue scenarios will help strengthen recommendations for rescue guidelines. METHODS: Twenty-eight healthy volunteers (18 men, 10 women) age 47±17 (range 20-73) (mean ±SD with range) underwent a mock rescue in which candidate patrollers completing an Outdoor Emergency Care course performed spine immobilization and back boarding in 3 scenarios: 1) Ski helmet on, no c-collar; 2) helmet on, with c-collar; and 3) helmet removed, with c-collar...
July 3, 2017: Wilderness & Environmental Medicine
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