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https://www.readbyqxmd.com/read/28441313/clinical-evidence-for-spinal-cord-stimulation-for-failed-back-surgery-syndrome-fbss-systematic-review
#1
Leonardo Kapural, Erika Peterson, David A Provenzano, Peter Staats
STUDY DESIGN: A systematic review OBJECTIVE.: A systematic literature review of the clinical data from prospective studies was undertaken to assess the efficacy of spinal cord stimulation (SCS) in the treatment of FBSS in adults. SUMMARY OF BACKGROUND DATA: For patients with unrelenting back pain due to mechanical instability of the spine, degenerative disc disease, spinal injury, or deformity, spinal surgery is a well-accepted treatment option; however, even after surgical intervention, many patients continue to experience chronic back pain that can be notoriously difficult to treat...
April 24, 2017: Spine
https://www.readbyqxmd.com/read/28439543/saving-the-injured-rescue-behavior-in-the-termite-hunting-ant-megaponera-analis
#2
Erik Thomas Frank, Thomas Schmitt, Thomas Hovestadt, Oliver Mitesser, Jonas Stiegler, Karl Eduard Linsenmair
Predators of highly defensive prey likely develop cost-reducing adaptations. The ant Megaponera analis is a specialized termite predator, solely raiding termites of the subfamily Macrotermitinae (in this study, mostly colonies of Pseudocanthotermes sp.) at their foraging sites. The evolutionary arms race between termites and ants led to various defensive mechanisms in termites (for example, a caste specialized in fighting predators). Because M. analis incurs high injury/mortality risks when preying on termites, some risk-mitigating adaptations seem likely to have evolved...
April 2017: Science Advances
https://www.readbyqxmd.com/read/28436583/physical-activity-and-exercise-for-chronic-pain-in-adults-an-overview-of-cochrane-reviews
#3
REVIEW
Louise J Geneen, R Andrew Moore, Clare Clarke, Denis Martin, Lesley A Colvin, Blair H Smith
BACKGROUND: Chronic pain is defined as pain lasting beyond normal tissue healing time, generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep disturbances, poor quality of life, and healthcare costs. Chronic pain has a weighted mean prevalence in adults of 20%.For many years, the treatment choice for chronic pain included recommendations for rest and inactivity. However, exercise may have specific benefits in reducing the severity of chronic pain, as well as more general benefits associated with improved overall physical and mental health, and physical functioning...
April 24, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28432149/cd73-on-t-cells-orchestrates-cardiac-wound-healing-after-myocardial-infarction-by-purinergic-metabolic-reprogramming
#4
Nadine Borg, Christina Alter, Nicole Görldt, Christoph Jacoby, Zhaoping Ding, Bodo Steckel, Christine Quast, Florian Bönner, Daniela Friebe, Sebastian Temme, Ulrich Flögel, Jürgen Schrader
Background -T-cells are required for proper healing after myocardial infarction. The mechanism of their beneficial action, however, is unknown. The pro-inflammatory "danger signal" adenosine triphosphate (ATP), released from damaged cells, is degraded by the ectonucleotidases CD39 and CD73 to the anti-inflammatory mediator adenosine. Here, we investigate the contribution of CD73-derived adenosine produced by T-cells to cardiac remodeling after ischemia/reperfusion and define its mechanism of action. Methods -Myocardial ischemia (50 min /reperfusion) was induced in global CD73(-/-) and CD4-CD73(-/-) mice...
April 21, 2017: Circulation
https://www.readbyqxmd.com/read/28427985/ureter-injury-as-a-complication-of-oblique-lumbar-interbody-fusion-a-case-report
#5
Hyeong-Jin Lee, Jin-Sung Kim, Kyeong-Sik Ryu, Choon Keun Park
BACKGROUND: Oblique lumbar interbody fusion is a commonly used surgical method of achieving lumbar interbody fusion. There have been some reports about complications of oblique lumbar interbody fusion at the L2-3 level. But to our knowledge, there have been no reports about ureter injury during oblique lumbar interbody fusion. We report a case of ureter injury during oblique lumbar interbody fusion to share our experience. CASE DESCRIPTION: A 78-year-old male patient presented with a history of lower back pain and neurogenic intermittent claudication...
April 17, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28427136/-effects-and-related-mechanism-of-bivalirudin-on-the-survival-of-random-skin-flap-on-the-back-of-rat
#6
L Y Cai, T Wang, D S Lin, D Lu
Objective: To investigate the effects and related mechanism of bivalirudin on the survival of random skin flap on the back of rat. Methods: Thirty SD rats were divided into bivalirudin group and normal saline group according to the random number table, with 15 rats in each group. The random flap model with size of 9 cm×3 cm was reproduced on the back of rats in two groups. Immediately post injury, rats in bivalirudin group were intraperitoneally injected with 5 mg/mL bivalirudin (0.8 mL/kg), while rats in normal saline group were intraperitoneally injected with normal saline (0...
April 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28426571/growth-differentiation-factor-5-accelerates-wound-closure-and-improves-skin-quality-during-repair-of-full-thickness-skin-defects
#7
Jennifer L Schiefer, Manuel Held, Paul C Fuchs, Erhan Demir, Frank Plöger, Hans-Eberhard Schaller, Afshin Rahmanian-Schwarz
BACKGROUND: A fast and stable wound closure is important, especially for extended and unstable wounds found after burn injuries. Growth can regulate a variety of cellular processes, including those involved in wound healing. Growth differentiation factor 5 (GDF-5) can accelerate fibroblast cell migration, cell proliferation, and collagen synthesis, which are essential for wound healing. Nevertheless, no standardized evaluation of the effect of GDF-5 on the healing of full-thickness wounds has been published to date...
May 2017: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/28426289/injuries-and-exposures-among-ocean-safety-providers-a-review-of-workplace-injuries-and-exposures-from-2007-2012
#8
Kevin M Ryan, Alan H Breaud, Laura Eliseo, Ralph Goto, Patricia Mitchell
OBJECTIVE: Research on workplace injuries and exposures in ocean safety personnel remains limited. Despite increasing beach attendance and reliance on lifeguards for protection, the most common types of injuries, equipment resulting in injuries and environmental exposures remains unknown. METHODS: This study reviewed OSHA 300 logs summarizing workers' compensation claims from 2007-2012 to identify common body parts injured, action at time of injury, equipment causing injury and environmental exposures...
April 20, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28425053/what-demographic-and-clinical-characteristics-correlate-with-expectations-with-trapeziometacarpal-arthritis
#9
Lana Kang, Joseph Nguyen, Sohaib Z Hashmi, Steve K Lee, Andrew J Weiland, Carol A Mancuso
BACKGROUND: Pretreatment variables have been shown to be associated with the fulfillment of patient expectations, yet in treating thumb trapeziometacarpal osteoarthritis (OA) it remains unclear how patient expectations correlate with the effectiveness of treatment. An increased understanding of the variables that affect patient expectations enables tailored patient education and patient-provider communication. QUESTIONS/PURPOSES: (1) Is there a correlation between patient demographics and clinical characteristics, and the expectations the patients have when seeking treatment for trapeziometacarpal OA? (2) What factors are independently associated with the total expectations score and frequency of expecting "back to normal" among patients treated for trapeziometacarpal OA? METHODS: Between March 2011 and October 2013, 89 patients of all 96 eligible patients seeking treatment for trapeziometacarpal OA were approached and agreed to participate in this study...
April 19, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28424597/working-memory-after-traumatic-brain-injury-the-neural-basis-of-improved-performance-with-methylphenidate
#10
Anne E Manktelow, David K Menon, Barbara J Sahakian, Emmanuel A Stamatakis
Traumatic brain injury (TBI) often results in cognitive impairments for patients. The aim of this proof of concept study was to establish the nature of abnormalities, in terms of activity and connectivity, in the working memory network of TBI patients and how these relate to compromised behavioral outcomes. Further, this study examined the neural correlates of working memory improvement following the administration of methylphenidate. We report behavioral, functional and structural MRI data from a group of 15 Healthy Controls (HC) and a group of 15 TBI patients, acquired during the execution of the N-back task...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28420353/the-influence-of-fatigue-and-chronic-low-back-pain-on-muscle-recruitment-patterns-following-an-unexpected-external-perturbation
#11
Júlia Jubany, Lieven Danneels, Rosa Angulo-Barroso
BACKGROUND: Chronic low back pain (CLBP) has been associated with altered trunk muscle responses as well as increased muscle fatigability. CLBP patients and fatigued healthy subjects could experience similar neuromuscular strategies to attempt to protect the spine. The current study examined muscle activation differences between healthy and CLBP subjects following a perturbation. In addition, the possible role of muscle fatigue was evaluated by investigating the healthy control subjects in a non-fatigued and a fatigued condition...
April 19, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28420077/recognition-of-the-duration-and-prediction-of-insect-prevalence-of-stored-rough-rice-infested-by-the-red-flour-beetle-tribolium-castaneum-herbst-using-an-electronic-nose
#12
Sai Xu, Zhiyan Zhou, Keliang Li, Sierra Mari Jamir, Xiwen Luo
The purpose of this research is to explore the feasibility of applying an electronic nose for the intelligent monitoring of injurious insects in a stored grain environment. In this study, we employed an electronic nose to sample rough rice that contained three degrees of red flour beetle (Tribolium castaneum Herbst) infestation for different durations-light degree (LD), middle degree (MD), and heavy degree (HD)-and manually investigated the insect situation at the same time. Manual insect situation investigation shows that, in all three rice treatments, the insect amounts gradually decreased after infestation...
April 14, 2017: Sensors
https://www.readbyqxmd.com/read/28416177/restoring-how-older-adults-manage-their-recovery-from-hip-fracture
#13
David J Healee, Antoinette McCallin, Marion Jones
AIMS AND OBJECTIVES: To generate a substantive theory that explained recovery from hip fracture from the perspective of older adults and find out how they managed it. BACKGROUND: Hip fracture is a well-researched phenomenon. The perspective of how older adults recover from hip fracture has been examined least of all. Patients spend less time in hospital following injury and generally recover in their home setting. DESIGN: A Glaserian grounded theory approach was used for this study...
March 9, 2017: International Journal of Orthopaedic and Trauma Nursing
https://www.readbyqxmd.com/read/28415935/naringenin-improves-the-healing-process-of-thermally-induced-skin-damage-in-rats
#14
Abdulaziz S Al-Roujayee
Objective To evaluate the effect of the phenolic compound naringenin on thermal burn-induced inflammatory responses and oxidative stress in rats. Methods First degree thermal burn injuries were induced in shaved rats by 10 s immersion of the back surface in water at 90℃. Naringenin treatment (25, 50 and 100 mg/kg/day) was initiated 24 h following burn injury, and continued for 7 days. On treatment day 7, serum tumour necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6, nitric oxide (NO), prostaglandin (PG)E2, caspase-3, leukotriene (LT)-B4 and nuclear factor (NF)-κB levels were quantified...
April 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28412987/back-pain-in-the-emergency-department-pathological-fracture-following-spinal-manipulation
#15
Christopher Skappak, Erik J Saude
Back pain is one of the most common presentations to the emergency department. Though case reports of patients presenting with increased back pain following chiropractic spinal manipulations are rare, we have identified a case rarely reported in the literature where a potential injury from chiropractic manipulation resulted in a diagnosis of multiple myeloma. We have reported a previously healthy 66-year-old male who presented with persistent lower back pain over 4 weeks. An initial evaluation with thoracolumbar radiographs revealed no significant findings...
April 17, 2017: CJEM
https://www.readbyqxmd.com/read/28412334/ovotestis-in-adolescence-two-case-reports
#16
Jyoti D Chouhan, David I Chu, Antoinette Birs, Louise C Pyle, Jason P Van Batavia, Rebecca L Linn, Susan J Back, Pierre Russo, Kassa Darge, Thomas F Kolon, Arun K Srinivasan
We present two patients found to have ovotesticular disorder of sexual differentiation (otDSD) in late adolescence. Two 15-year-old phenotypically male patients presented to a large pediatric hospital with different complaints: one with concern for testicular rupture after a straddle injury; the other with gynecomastia. Further work-up, including imaging and lab tests, was performed before surgical exploration. The first patient had unilateral ovotestis, contralateral testis, and SRY-negative 46,XX karyotype...
April 13, 2017: Urology
https://www.readbyqxmd.com/read/28409669/treatment-of-thoracolumbar-burst-fractures-extended-follow-up-of-a-randomized-clinical-trial-comparing-orthosis-versus-no-orthosis
#17
Jennifer C Urquhart, Osama A Alrehaili, Charles G Fisher, Alyssa Fleming, Parham Rasoulinejad, Kevin Gurr, Stewart I Bailey, Fawaz Siddiqi, Christopher S Bailey
OBJECTIVE A multicenter, prospective, randomized equivalence trial comparing a thoracolumbosacral orthosis (TLSO) to no orthosis (NO) in the treatment of acute AO Type A3 thoracolumbar burst fractures was recently conducted and demonstrated that the two treatments following an otherwise similar management protocol are equivalent at 3 months postinjury. The purpose of the present study was to determine whether there was a difference in long-term clinical and radiographic outcomes between the patients treated with and those treated without a TLSO...
April 14, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28409514/neck-strength-and-self-reported-neck-dysfunction-what-is-the-impact-of-a-season-of-rugby-union
#18
Danielle M Salmon, S John Sullivan, Phil Handcock, Nancy J Rehrer, Brian Niven
BACKGROUND: Neck strength has been reported to reduce the incidence of concussions and neck injuries. However little is known about how neck strength changes over a playing season. AIM: To understand the impact a 20-week rugby season has on neck strength, neck pain (NP) and neck stiffness (NS) in a cohort of rugby players, relative to a non-contact control group. METHODS: This prospective cohort study employed a fixed-frame dynamometer to measure neck strength in a simulated contact posture in rugby players (n=32) and controls (n=15)...
April 13, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28409199/disc-degeneration-on-mri-is-more-prevalent-in-young-elite-skiers-compared-to-controls
#19
Wisam A Witwit, Peter Kovac, Anna Sward, Cecilia Agnvall, Carl Todd, Olof Thoreson, Hanna Hebelka, Adad Baranto
PURPOSE: Evidence-based facts regarding spine abnormalities and back pain are needed in order to develop rehabilitation programs and prevent spine injuries in young skiers. The aim therefore is to identify MRI changes in the thoraco-lumbar spine and the lifetime prevalence of back pain, as well as the association between them, in young skiers compared to non-athletes. METHODS: Seventy-five young elite alpine and mogul skiers, age range 16-20 years, were compared with 27 non-athletic controls...
April 13, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28404613/risk-factors-of-non-specific-neck-pain-and-low-back-pain-in-computer-using-office-workers-in-china-a-cross-sectional-study
#20
Sunyue Ye, Qinglei Jing, Chen Wei, Jie Lu
OBJECTIVES: Several studies have found that inappropriate workstations are associated with musculoskeletal disorders. The present cross-sectional study aimed to identify the risk factors of non-specific neck pain (NP) and low back pain (LBP) among computer-using workers. DESIGN: Observational study with a cross-sectional sample. SETTING: This study surveyed 15 companies in Zhejiang province, China. PARTICIPANTS: After excluding participants with missing variables, 417 office workers, including 163 men and 254 women, were analyzed...
April 11, 2017: BMJ Open
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