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Infectios disease

Ping Rong, Rong Ma, Quan-Hui Liu, Hai-Hong Yan, Si-Yuan Hu, Xin-Min Li, Xi-Lian Zhang, Wen-Ke Zheng
Acute upper respiratory tract infection is the most common infectious disease in children's respiratory system. The pathogen to the main virus, can account for more than 90% of the primary upper respiratory tract infectio. However, there is no specific anti-viral drugs specifically for the disease, in addition to the existence of excessive, widespread use or even abuse of antibiotics.Long-term clinical practice has confirmed that Chinese medicine is safe and effective in treating acute upper respiratory tract infection in children...
April 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
María José Mellado Peña, Begoña Santiago García, Fernando Baquero-Artigao, David Moreno Pérez, Roi Piñeiro Pérez, Ana Méndez Echevarría, José Tomás Ramos Amador, David Gómez-Pastrana Durán, Antoni Noguera Julian
Tuberculosis (TB) is the most important infectious disease all over the world, with a high morbidity and mortality. Pediatric tuberculosis has been a neglected epidemic, due to the difficulties in assessing its global impact, reduced incidence and lower infectivity compared to adults. In 2015, the WHO reported 1 million cases of paediatric TB and 169,000 deaths. In Europe, the emergence of MDR TB is a major concern, representing 16% of the new diagnosis in Eastern Europe. In 2014, it was estimated that about 219,000 children were infected by MDR-TB-strains in Europe, and 2,120 developed the disease...
January 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
Artur Yakimovich, Yauhen Yakimovich, Michael Schmid, Jason Mercer, Ivo F Sbalzarini, Urs F Greber
Viruses spread between cells, tissues, and organisms by cell-free and cell-cell mechanisms, depending on the cell type, the nature of the virus, or the phase of the infection cycle. The mode of viral transmission has a large impact on disease development, the outcome of antiviral therapies or the efficacy of gene therapy protocols. The transmission mode of viruses can be addressed in tissue culture systems using live-cell imaging. Yet even in relatively simple cell cultures, the mechanisms of viral transmission are difficult to distinguish...
January 2016: MSphere
Piotr Tetlak, Christiane Ruedl
The Clec9A-diphtheria toxin receptor (DTR) transgenic mouse strain provides a robust animal model to study the function of lymphoid organ-resident CD8(+) dendritic cells (DCs) and nonlymphoid organ-specific CD103(+) DCs in infectioous diseases and inflammation. Here we describe some basic protocols for CD8(+)/CD103(+) DC isolation, for their in vivo depletion, and for their characterization by multi-color flow cytometry analysis. As an example for in vivo functional characterization of this DC subset, we present here the experimental cerebral malaria model...
2016: Methods in Molecular Biology
Rodrigo Ríos, Salim Mattar, Marco González
OBJECTIVE: Analysing scientific production in the area of infectious diseases in Colombia, 2000-2009. MATERIAL AND METHODS: A literature search was made in category A journals in Colciencias' Publindex. The journals were: Biomédica, Revista de Salud Pública (Universidad Nacional), Colombia Médica, Ciencias Pecuarias, Latreia, MVZ Córdoba, Revista de Medicina (Universidad Nacional) and Infectio. RESULTS: 2,963 publications were found; 2,744 (92...
April 2011: Revista de Salud Pública
Deborah Money, Simon Dobson, Lesley Cole, Eda Karacabeyli, Edith Blondel-Hill, Ruth Milner, Eva Thomas
OBJECTIVE: To evaluate the sensitivity, specificity, and feasibility of a rapid real-time polymerase chain reaction (PCR) test for group B streptococcus (GBS) completed during labour, compared with the standard culture test performed at 35 to 37 weeks' gestation. METHODS: Women presenting to the maternity unit for term vaginal delivery had two vaginal/rectal samples collected. One swab was tested using a rapid PCR method (IDI-Strep B, Infectio Diagnostic [IDI] Inc...
September 2008: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
V G Nesterenko, V A Akovbian, E N Semenova, L M Vavilova, T I Iudina
During the last STDs'epidemic in Russia (1994 - 2004) over 2.7 min people have been infected with syphilis. At present the structure of syphilis morbidity is characterized by 37% of latent forms, including 1.5% late latency. The increased level of late latency may result from: an ever-growing number of those with asymptomatic syphilis; disorderly and self-dependent usage of antibacterial preparations; spread of the virus chronic infections (herpes, hepatitis B, C) altering the macroorganism immune response; alcohol and drug abuse which decreases the efficacy of specific therapy...
July 2006: Zhurnal Mikrobiologii, Epidemiologii, i Immunobiologii
S Ranque, B Marchou, D Malvy, E Adehossi, R Laganier, H Tissot-Dupont, A Lotte, S Dydymsky, J Durant, J-P Stahl, A Bosseray, J Gaillat, A Sotto, C Cazorla, J-M Ragneau, P Brouqui, J Delmont et al.
BACKGROUND: Data about anti-malarial drugs prescription practices in Europe and the safety of imported malaria treatments are scanty. In 1999, a French consensus development conference published guidelines for the prevention and treatment of imported P. falciparum malaria. The impact of these guidelines has not been evaluated. AIM: To investigate the impact of these guidelines on the prescription of anti-malarials, and to evaluate the incidence of acute drug events (ADEs) leading to discontinuation of treatment...
October 2005: QJM: Monthly Journal of the Association of Physicians
H Dele Davies, Mark A Miller, Sebastian Faro, Dan Gregson, Sue C Kehl, Jeanne A Jordan
BACKGROUND: Current prevention of infection due to group B Streptococcus (GBS) involves giving intrapartum antibiotics to women on the basis of either antenatal culture colonization status or presence of risk factors. METHODS: We prospectively compared the performance characteristics of a rapid molecular diagnostic test (IDI-Strep B; Infectio Diagnostic) with culture for intrapartum GBS detection after 36 weeks' gestation in 5 North American centers during the period September 2001-May 2002...
October 15, 2004: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Sékéné Badiaga, Karine Barrau, Philippe Brouqui, Jacques Durant, Denis Malvy, François Janbon, Eric Bonnet, Annick Bosseray, Albert Sotto, Dominique Peyramont, Serge Dydymski, Celine Cazorla, Hervé Tolou, Jean Paul Durant, Jean Delmont et al.
Dengue fever (DF) is a mosquito-transmitted acute disease caused by any of four dengue flavivirus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4) which is becoming a major public health problem in intertropical areas.1 DF is increasingly observed in febrile travelers returning from tropical areas,2 especially those returning from the Caribbean islands and Southeast Asia, but it is rarely diagnosed in travelers returning from Africa.3-8 Diagnosis is often serologic, and in most cases is not confirmed; virus isolation remains exceptional...
September 2003: Journal of Travel Medicine
H Laurichesse, A Sotto, E Bonnet, B Abraham, D Neau, S Badiaga, J Gaillat, P Fabbro-Peray et al.
A prospective, hospital-based, multicenter study was undertaken to identify the reasons for hospital admission, to describe antibiotic treatment before and during hospitalization, and to determine the outcome of community-acquired pneumonia (CAP). Data collected included prehospital management of CAP, Pneumonia Outcome Research Team (PORT) classification on admission, in-hospital antibiotic treatment, and predictors of death within 30 days. Among the 215 patients (mean age, 66.7 years; M:F ratio, 1.1) recruited, 24 (11...
November 2001: European Journal of Clinical Microbiology & Infectious Diseases
B Abraham, O Baud, E Bonnet, P M Roger, I Chossat, C Merle, J Reynes
OBJECTIVES: To describe and analyze the clinical and biological manifestations of thrombotic microangiopathy (TMA) and evaluate the therapeutic strategies. METHODS: A retrospective study was performed in 14 infectious diseases units of southern France. All HIV patients presenting TMA during the last decade were selected (n = 14). RESULTS: The principle signs observed, aside from defining TMA (association of microangiopathic hemolytic anemia, thrombocytopenia and renal failure), were diarrhea (n = 9) and a high level of lacticodehydrogenase (LDH)...
March 31, 2001: La Presse Médicale
S Badiaga, J Delmont, P Brouqui, F Janbon, J Durant, A Bosseray, D Malvy, E Bonnet, A Sotto, S Dydymski, D Peyramond
Imported dengue is increasingly observed in non endemic countries. We report a retrospective study of 44 cases of dengue fever diagnosed in nine french university hospitals between 1994 and 1997. The patients were aged between 13 and 67 years. Most of them were tourists and had been traveling for a few weeks, in French West Indies and French Guyana (18), South-East Asia (10), India (7) or Polynesia (4). Only, two contracted the disease in Africa. The onset of symptoms preceded the return or followed it within 7 days...
May 1999: Pathologie-biologie
J L Kalliomäki, R Leino
In 1971-73, 60 patients were hospitalized for an infectios disease caused by Y. enterocolitica serotypes III and IX or Y. pseudotuberculosis serotype I. In the spring of 1977 a follow-up study was carried out with 52 of these patients, one patient having died from intestinal perforation evidently resulting from yersiniosis-induced amyloidosis and colitis. The follow-up study showed that two patients had symptoms of sacroilitis, one had developed an apparent rheumatoid arthritis after yersiniosis and one had joint plans and a high serum rheumatoid factor titer with no objective joint changes...
1979: Acta Medica Scandinavica
P Steinbrück
The development of the epidemiology of tuberculosis in GDR from 1949 is evaluated. The factors deeply influencing incidence and prevalence of tuberculosis in GDR are: the socioeconomic development of a socialist society with continuous increase of living standard and social fonds, the state of the socialist public health system in general, and the special services and methods for the control of tuberculosis in the chest clinics and hospitals. Tuberculosis is no more a common disease in GDR. Tubercle bacilli are more ubiquitous, but are confined to distinct sources...
1977: Zeitschrift Für Erkrankungen der Atmungsorgane
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