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https://www.readbyqxmd.com/read/29123931/rapid-ascending-sensorimotor-paralysis-hearing-loss-and-fatal-arrhythmia-in-a-multimorbid-patient-due-to-an-accidental-overdose-of-fluoxetine
#1
Matthew Herrmann, Prissilla Xu, Antonio Liu
Background: Common side effects of selective serotonin reuptake inhibitors (SSRIs) include tachycardia, drowsiness, tremor, nausea, and vomiting. Although SSRIs have less toxic side effects compared to more traditional antidepressants, serious and life threatening cases of SSRI overdose have been reported. We describe a 24-year-old multimorbid female who presented to the emergency department with rapid onset ascending sensorimotor paralysis, complicated by respiratory and cardiac arrest, found to have fatal levels of fluoxetine by toxicological analysis, not taken in a suicidal act...
2017: Case Reports in Neurological Medicine
https://www.readbyqxmd.com/read/28686082/providing-dementia-consultations-to-veterans-using-clinical-video-telehealth-results-from-a-clinical-demonstration-project
#2
Stuti Dang, Carlos A Gomez-Orozco, Maria H van Zuilen, Silvina Levis
PURPOSE: Veterans with dementia and their caregivers in remote areas may not have access to specialists to provide diagnosis, treatment, and education. The purpose of this clinical demonstration project was to examine the feasibility, acceptability, and impact of a video consultations clinic for veterans with dementia or memory complaints and their caregivers. METHODS: The dementia clinical video telehealth (CVT) consultation clinic was established to identify, diagnose, and treat dementia in veterans at sites distant from the main medical center...
July 7, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/28422897/outcomes-associated-with-blast-versus-nonblast-related-traumatic-brain-injury-in-us-military-service-members-and-veterans-a-systematic-review
#3
Nancy Greer, Nina Sayer, Eva Koeller, Tina Velasquez, Timothy J Wilt
OBJECTIVES: To systematically review the literature on comparative clinical and functional outcomes following blast-related versus nonblast-related traumatic brain injury (TBI) among US service members and Veterans. DESIGN: MEDLINE search (January 2001 to June 2016) supplemented with hand search of reference lists and input from peer reviewers. RESULTS: Thirty-one studies (in 33 articles) reported on health outcomes; only 2 were rated low risk of bias...
April 18, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28322446/increased-long-term-risk-of-hearing-loss-in-patients-with-traumatic-brain-injury-a-nationwide-population-based-study
#4
Wei-Chuan Shangkuan, Hung-Che Lin, Cheng-Ping Shih, Chun-An Cheng, Hueng-Chuen Fan, Chi-Hsiang Chung, Fu-Huang Lin, Chang-Huei Tsao, Wu-Chien Chien
OBJECTIVES/HYPOTHESIS: We investigated incidences of hearing loss among patients with traumatic brain injury (TBI) to evaluate whether they had a higher risk of hearing loss than the general population. STUDY DESIGN: Cohort study. METHODS: Inpatient data from the Taiwan National Health Insurance Research Database from January 1, 2000 to December 31, 2010 were recorded. Patients with TBI and a retrospective comparison cohort were analyzed. Each subject was individually traced from their index date to identify subjects who subsequently received a diagnosis of hearing loss...
November 2017: Laryngoscope
https://www.readbyqxmd.com/read/28319479/brainstem-evoked-potential-indices-of-subcortical-auditory-processing-after-mild-traumatic-brain-injury
#5
Kathy R Vander Werff, Brian Rieger
OBJECTIVES: The primary aim of this study was to assess subcortical auditory processing in individuals with chronic symptoms after mild traumatic brain injury (mTBI) by measuring auditory brainstem responses (ABRs) to standard click and complex speech stimuli. Consistent with reports in the literature of auditory problems after mTBI (despite normal-hearing thresholds), it was hypothesized that individuals with mTBI would have evidence of impaired neural encoding in the auditory brainstem compared to noninjured controls, as evidenced by delayed latencies and reduced amplitudes of ABR components...
July 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28153668/prevalence-of-hearing-loss-and-tinnitus-in-iraq-and-afghanistan-veterans-a-chronic-effects-of-neurotrauma-consortium-study
#6
A A Swan, J T Nelson, B Swiger, C A Jaramillo, B C Eapen, M Packer, M J Pugh
The purpose of this study was to describe the prevalence of hearing loss and tinnitus in a cohort of Iraq and Afghanistan Veterans (IAV) with common post-deployment conditions, including traumatic brain injury (TBI), post-traumatic stress disorder (PTSD), and other typical post-concussive conditions such as headaches and vertigo/dizziness. This retrospective observational study used data from the national Veterans Health Administration (VA) data repository from fiscal years 2001-2014. Veteran data was included if there were at least three years of VA care, with one or more years of care in 2007 or after...
June 2017: Hearing Research
https://www.readbyqxmd.com/read/27613210/hearing-loss-and-tinnitus-in-military-personnel-with-deployment-related-mild-traumatic-brain-injury
#7
Stephanie J Karch, José E Capó-Aponte, D Scott McIlwain, Michael Lo, Sridhar Krishnamurti, Roger N Staton, Kendra Jorgensen-Wagers
The objective of this study was to analyze differences in incidence and epidemiologic risk factors for significant threshold shift (STS) and tinnitus in deployed military personnel diagnosed with mild traumatic brain injury (mTBI) due to either a blast exposure or nonblast head injury. A retrospective longitudinal cohort study of electronic health records of 500 military personnel (456 met inclusion criteria) diagnosed with deployment-related mTBI was completed. Chi-square tests and STS incidence rates were calculated to assess differences between blast-exposed and nonblast groups; relative risks and adjusted odds ratios of developing STS or tinnitus were calculated for risk factors...
October 2016: U.S. Army Medical Department Journal
https://www.readbyqxmd.com/read/27085885/post-traumatic-deafness-a-pictorial-review-of-ct-and-mri-findings
#8
REVIEW
Olivier Maillot, Arnaud Attyé, Eric Boyer, Olivier Heck, Adrian Kastler, Sylvie Grand, Sébastien Schmerber, Alexandre Krainik
UNLABELLED: Hearing loss is a common functional disorder after trauma, and radiologists should be aware of the ossicular, labyrinthine or brain lesions that may be responsible. After a trauma, use of a systematic approach to explore the main functional components of auditory pathways is essential. Conductive hearing loss is caused by the disruption of the conductive chain, which may be due to ossicular luxation or fracture. This pictorial review firstly describes the normal 2-D and 3-D anatomy of the ossicular chain, including the incudo-malleolar and incudo-stapedial joints...
June 2016: Insights Into Imaging
https://www.readbyqxmd.com/read/26968826/auditory-hallucinations-in-cognitive-neurology
#9
A Robles Bayón, M G Tirapu de Sagrario, F Gude Sampedro
INTRODUCTION: Different types and localisations of neurological lesions can produce tinnitus and verbal or musical hallucinations (VMH). METHOD: These symptoms were screened for in 1,000 outpatients at a cognitive neurology clinic, and epidemiological and neuroimaging data were recorded. RESULTS: Tinnitus was present in 6.9% of the total and VMH in 0.9%. The paracusia group was predominantly female but the difference was not statistically significant...
July 2017: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/26807789/emerging-technologies-with-potential-for-objectively-evaluating-speech-recognition-skills
#10
REVIEW
Vishakha Waman Rawool
Work-related exposure to noise and other ototoxins can cause damage to the cochlea, synapses between the inner hair cells, the auditory nerve fibers, and higher auditory pathways, leading to difficulties in recognizing speech. Procedures designed to determine speech recognition scores (SRS) in an objective manner can be helpful in disability compensation cases where the worker claims to have poor speech perception due to exposure to noise or ototoxins. Such measures can also be helpful in determining SRS in individuals who cannot provide reliable responses to speech stimuli, including patients with Alzheimer's disease, traumatic brain injuries, and infants with and without hearing loss...
2016: International Journal of Audiology
https://www.readbyqxmd.com/read/26350991/lamotrigine-induced-tubulointerstitial-nephritis-and-uveitis-atypical-cogan-syndrome
#11
Anton M Kolomeyer, Shyam Kodati
PURPOSE: To report a case of lamotrigine-induced tubulointerstitial nephritis and uveitis (TINU)-atypical Cogan syndrome. METHODS: Case report. RESULTS: A 16-year-old boy with traumatic brain injury and seizures presented to the emergency department with facial swelling, rash, and back pain several days after increasing lamotrigine dose secondary to a breakthrough seizure. Creatinine, urine β2 microglobulin, and eosinophils were elevated...
January 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/25757582/-it-s-the-hearing-that-is-last-to-go-a-case-of-traumatic-head-injury
#12
Kate Tapson, Wanda Sierotowicz, Di Marks-Maran, Trish Morris Thompson
This article explores the literature related to acquired brain injury (ABI) and is followed by a case study of one patient with ABI, which reflects how the evidence, when implemented by a team of health professionals, can have a positive impact on recovery. Gregor is a middle-aged Polish man who suffered traumatic ABI when knocked down by a car. He spent a number of years in a specialist neurosurgical unit, then a rehabilitation unit, and for the past several years has been cared for in a care home. For most of this time he was in a coma...
March 11, 2015: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/25243188/adenosine-amine-congener-as-a-cochlear-rescue-agent
#13
Srdjan M Vlajkovic, Hao Chang, Song Yee Paek, Howard H-T Chi, Sreevalsan Sreebhavan, Ravindra S Telang, Malcolm Tingle, Gary D Housley, Peter R Thorne
UNLABELLED: We have previously shown that adenosine amine congener (ADAC), a selective A1 adenosine receptor agonist, can ameliorate noise- and cisplatin-induced cochlear injury. Here we demonstrate the dose-dependent rescue effects of ADAC on noise-induced cochlear injury in a rat model and establish the time window for treatment. METHODS: ADAC (25-300 μg/kg) was administered intraperitoneally to Wistar rats (8-10 weeks old) at intervals (6-72 hours) after exposure to traumatic noise (8-16 kHz, 110 dB sound pressure level, 2 hours)...
2014: BioMed Research International
https://www.readbyqxmd.com/read/24662845/therapeutic-effect-of-sildenafil-on-blast-induced-tinnitus-and-auditory-impairment
#14
G Mahmood, Z Mei, H Hojjat, E Pace, S Kallakuri, J S Zhang
Blast-induced tinnitus, along with associated auditory impairment and traumatic brain injury, is a primary concern facing military service members. To search for treatment, we investigated the therapeutic effects of sildenafil, a phosphodiesterase-5 inhibitor, given its vasodilatory effects and evidence suggesting its beneficial effects on noise-induced hearing loss. Rats were subjected to three consecutive blast exposures at 22 psi and were monitored for tinnitus using a gap-detection acoustic startle reflex paradigm...
June 6, 2014: Neuroscience
https://www.readbyqxmd.com/read/24655334/blast-related-mild-traumatic-brain-injury-in-the-acute-phase-acute-stress-reactions-partially-mediate-the-relationship-between-loss-of-consciousness-and-symptoms
#15
COMPARATIVE STUDY
Jacob N Norris, Richard Sams, Peter Lundblad, Earl Frantz, Erica Harris
PRIMARY OBJECTIVE: The objective was to compare symptoms in service members diagnosed with a blast-related mTBI (mild traumatic brain injury) with a loss of consciousness (LOC) to those without LOC. RESEARCH DESIGN: Clinicians saw US military personnel within 72 hours of sustaining a blast-related mTBI and at a follow-up visit 48-72 hours later (n = 210). METHODS AND PROCEDURES: Demographics, post-concussive symptoms, diagnosis of acute stress reaction (ASR) and simple reaction time data from the Automated Neuropsychological Assessment Metric (ANAM) were collected...
2014: Brain Injury: [BI]
https://www.readbyqxmd.com/read/24581913/population-based-inception-cohort-study-of-the-incidence-course-and-prognosis-of-mild-traumatic-brain-injury-after-motor-vehicle-collisions
#16
J David Cassidy, Eleanor Boyle, Linda J Carroll
OBJECTIVE: To determine the incidence, course, and prognosis of adult mild traumatic brain injury (MTBI) caused by motor vehicle collisions. DESIGN: Prospective, population-based, inception cohort study. SETTING: The province of Saskatchewan, Canada, with a population of about 1,000,000 inhabitants. PARTICIPANTS: All adults (N=1716) incurring an MTBI in a motor vehicle collision between November 1997 and December 1999 in Saskatchewan...
March 2014: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/24343023/the-implications-of-physical-injury-on-otovestibular-and-cognitive-symptomatology-following-blast-exposure
#17
Christopher M Johnson, Colleen F Perez, Michael E Hoffer
OBJECTIVE: Identify a potential difference in the spectrum of otovestibular and cognitive symptoms in blast-exposed patients comparing individuals with or without significant extremity injuries. STUDY DESIGN: Case series with chart review. SETTING: A military tertiary care medical center. SUBJECTS AND METHODS: All new patient referrals for otovestibular evaluation after a blast injury or exposure were identified in the electronic medical record...
March 2014: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/24275459/correlation-of-otologic-complaints-in-soldiers-with-speech-disorders-after-traumatic-brain-injury
#18
Gregory R Dion, Courtney L Miller, Peter D O'Connor, N Scott Howard
OBJECTIVES/HYPOTHESIS: To determine the prevalence of otologic complaints in subjects with dysphonia and traumatic brain injury (TBI) in a sample population of the US Army. STUDY DESIGN: Cross-sectional study. METHODS: A total of 292 subjects were identified with a new diagnosis of voice disorder during a 3.5-year period at three large military medical centers. Of them, 70 subjects were also identified with TBI and had no history of dysphonia before this time period...
January 2014: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/24161764/-hereditary-optic-neuropathies-from-clinical-signs-to-diagnosis
#19
REVIEW
I Meunier, G Lenaers, C Hamel, S Defoort-Dhellemmes
Inherited optic atrophy must be considered when working up any optic nerve involvement and any systemic disease with signs of optic atrophy, even with a negative family history. There are two classical forms: dominant optic atrophy, characterized by insidious, bilateral, slowly progressive visual loss and temporal disc pallor, and Leber's optic atrophy, characterized by acute loss of central vision followed by the same event in the fellow eye within a few weeks to months, with disc hyperemia in the acute phase...
December 2013: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/23964046/unusual-delayed-presentation-of-head-trauma-complicating-outcome-of-facial-nerve-decompression-surgery
#20
J S Thakur, Vidya Shekar, Manika Saluja, N K Mohindroo
Late presentation of head trauma is rare. A young boy presented with a traumatic facial paralysis after head trauma. A CT scan of the head showed temporal bone fracture without intracranial insult. Facial nerve decompression was performed and paralysis started improving. However, he presented with vertigo and sensorineural hearing loss after 2 months. Clinical examination also showed cerebellar sign. We suspected iatrogenic injury to the cochlea; however, brain MRI showed haemorrhage in the area of anterior inferior cerebellar artery...
2013: BMJ Case Reports
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