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https://www.readbyqxmd.com/read/27747855/r%C3%A3-%C3%A5-nice-zale%C3%A5-ne-od-p%C3%A5-ci-w-uk%C3%A5-adzie-%C3%A5-ylnym-serca-potencjalne-wyt%C3%A5-umaczenie-dla-r%C3%A3-%C3%A5-nic-w-odpowiedzi-na-terapi%C3%A4-resynchronizuj%C3%A4-ca
#1
Agnieszka Młynarska, Rafał Młynarski, Krzysztof S Gołba, Maciej Sosnowski
BACKGROUND: We hypothesized that small differences in the anatomy of the coronary venous tree might be one of the factors responsible for the differences in the respond for cardiac resynchronization depending on a patient's gender. METHODS: The cardiac computed tomography scans with retrospective gating were performed on 315 subjects (aged 58.3 ± 11.6; 117 women) according to the clinical criteria. The standard protocol for coronary arteries was used during scanning...
October 17, 2016: Kardiologia Polska
https://www.readbyqxmd.com/read/27571559/-i-costi-farmacologici-della-terapia-di-conversione-con-farmaci-biologici-nel-carcinoma-del-colon-retto-con-metastasi-epatiche
#2
Jacopo Giuliani, Andrea Bonetti
Riassunto. Lo scopo di questo studio è quello di valutare i costi dei farmaci (con particolare riferimento alle terapie con farmaci biologici) utilizzati nella terapia di conversione in una popolazione non selezionata di pazienti affetti da carcinoma del colon-retto in stadio avanzato, al fine di ottenere una resezione epatica R0. In questa rassegna sono stati selezionati i report completi e gli aggiornamenti di tutti gli studi clinici randomizzati (di fase II e fase III) che confrontassero almeno 2 regimi di terapia con farmaci biologici in prima linea in pazienti affetti da carcinoma del colon-retto in stadio avanzato di malattia...
August 2016: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/27218249/-extracorporeal-shockwave-terapy-in-sports-and-non-sports-population-preliminary-results
#3
N Serviat-Hung, W Carvajal-Veitía, M Medina-Sánchez, Y Gutiérrez-Jorge, A Croas-Fernández
BACKGROUND: Inflammatory and calcifying diseases of the soft tissues are disorders having significant economical and social repercussions. They can be treated with drugs or physical therapy, and if these fail, surgery used to be the last existing therapeutic step. In recent years, a non-surgical alternative is being used to treat them, the application of extracorporeal shock waves. This work aims to verify the capacity of this therapeutic technique to diminish pain and to define its application rules...
September 2015: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/27183513/-malattia-di-marchiafava-bignami-con-coinvolgimento-della-corteccia-frontale-e-insorgenza-tardiva-di-sintomi-psichiatrici-resistenti-un-caso-clinico
#4
Carla Gramaglia, Alessandro Feggi, Camilla Vecchi, Sarah Di Marco, Alessandra Venesia, Claudia Delicato, Nunzia Chieppa, Fabiola De Marchi, Roberto Cantello, Patrizia Zeppegno
RIASSUNTO. Scopo. Descrivere il management di un paziente con malattia di Marchiafava-Bignami (MBD) associata a lesioni frontali corticali, senza sintomi specifici al primo accesso in Pronto Soccorso, e insorgenza tardiva di sintomi psichiatrici atipici. Metodi. Descriviamo il caso di un paziente di 44 anni con storia di abuso cronico di alcol, a cui è stata diagnosticata la MBD. Risultati. La risonanza magnetica ha evidenziato lesioni nello splenio e corpo del corpo calloso e lesioni bilaterali della corteccia frontale...
March 2016: Rivista di Psichiatria
https://www.readbyqxmd.com/read/26981031/extracorporeal-shockwave-terapy-to-treat-chronic-muscle-injury
#5
Diego Costa Astur, Bruno Santos, Eduardo Ramalho de Moraes, Gustavo Gonçalves Arliani, Paulo Roberto Dias Dos Santos, Alberto de Castro Pochini
OBJECTIVE: To evaluate the low energy extracorporeal shock waves therapy (ESWT) associated with physical therapy in the treatment of chronic muscle injuries classified as grades 2 and 3 in the lower limbs of amateur athletes. METHODS: Eight athletes presenting with lower limb muscle injury for more than three weeks were treated with physiotherapy and ESWT. We evaluated the following parameters during treatment: palpable gap, muscle strength, pain, and Tegner score, as well as ultrasound image features and the ability to return to sports practice...
September 2015: Acta Ortopedica Brasileira
https://www.readbyqxmd.com/read/26825046/the-importance-of-mortality-risk-assessment-validation-of-the-pediatric-index-of-mortality-3-score
#6
Andrea Wolfler, Raffaella Osello, Jenny Gualino, Edoardo Calderini, Gianluca Vigna, Pierantonio Santuz, Angela Amigoni, Fabio Savron, Fabio Caramelli, Emanuele Rossetti, Corrado Cecchetti, Maurizio Corbari, Marco Piastra, Raffaele Testa, Giancarlo Coffaro, Giusi Stancanelli, Eloisa Gitto, Roberta Amato, Federica Prinelli, Ida Salvo
OBJECTIVE: To evaluate the performance of the newest version of the Pediatric Index of Mortality 3 score and compare it with the Pediatric Index of Mortality 2 in a multicenter national cohort of children admitted to PICU. DESIGN: Retrospective, prospective cohort study. SETTING: Seventeen Italian PICUs. PATIENTS: All children 0 to 15 years old admitted in PICU from January 2010 to October 2014. INTERVENTIONS: None...
March 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/26759746/clinical-impact-of-bacterial-contamination-of-perfusion-fluid-in-kidney-transplantation
#7
A Ranghino, D Diena, F Simonato, M Messina, M Burdese, V Piraina, F Fop, G P Segoloni, L Biancone
Contamination of perfusion fluid (PF) could lead to serious infections in kidney transplant recipients. Preemptive therapy (PE-T) in case of yeast contamination of PF is mandatory. The usefulness of PE-T in presence of bacteria remains unclear. In this study we evaluated the incidence of PF bacterial contamination and the impact of PE-T on clinical outcome. Microbiological data of 290 PF and clinical data of the corresponding recipients collected in our hospital from January 2010 and December 2012 were analyzed...
2016: SpringerPlus
https://www.readbyqxmd.com/read/25807737/-paravicini-bagliani-a-a-cura-di-terapie-e-guarigioni-convegno-internazionale-di-storia-della-medicina-ariano-irpino-5-7-ottobre-2008-firenze-sismel-edizioni-del-galluzzo-2010-edizione-nazionale-la-scuola-medica-salernitana-pp-xiv-418
#8
https://www.readbyqxmd.com/read/24456785/systematic-review-and-meta-analysis-of-target-terapies-for-the-treatment-of-metastatic-renal-cancer
#9
REVIEW
Marcela Durán, Wagner Matheus, Ubirajara Ferreira, Otávio Clark
OBJECTIVES: At present there are several drugs for the treatment of advanced renal cell carcinoma (ARCC). The main objective of this work was to perform a systematic review (SR) and meta-analysis (MA) of clinical randomized studies that compared target cell therapies (TCT). MATERIALS AND METHODS: SR identified clinical randomized trials that compared TCT versus interferon-alpha in the treatment of patients with ARCC. In order to analyze efficiency, it was evaluated free-survival progression (FSP), total survival (TS) and response rate (RR)...
November 2013: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/23493168/pregnancy-disorders-leading-to-very-preterm-birth-influence-neonatal-outcomes-results-of-the-population-based-action-cohort-study
#10
Luigi Gagliardi, Franca Rusconi, Monica Da Frè, Giorgio Mello, Virgilio Carnielli, Domenico Di Lallo, Francesco Macagno, Silvana Miniaci, Carlo Corchia, Marina Cuttini
Background:We examined the relationships between -pregnancy disorders leading to very preterm birth -(spontaneous preterm labor, prelabor premature rupture of -membranes (PPROM), hypertension/preeclampsia, -intrauterine growth restriction (IUGR), antenatal hemorrhage, and maternal -infection), both in isolation and grouped together as -"disorders of placentation" (hypertensive disorders and IUGR) vs. -"presumed infection/inflammation" (all the others), and several unfavorable neonatal outcomes.Methods:We examined a population-based prospective cohort of 2,085 singleton infants of 23-31 wk gestational age (GA) born in six Italian regions (the Accesso alle Cure e Terapie Intensive Ostetriche e Neonatali (ACTION) study)...
June 2013: Pediatric Research
https://www.readbyqxmd.com/read/23337093/cause-specific-mortality-of-very-preterm-infants-and-antenatal-events
#11
Carlo Corchia, Pierpaolo Ferrante, Monica Da Frè, Domenico Di Lallo, Luigi Gagliardi, Virgilio Carnielli, Silvana Miniaci, Simone Piga, Francesco Macagno, Marina Cuttini
OBJECTIVE: To assess the relationship between antenatal factors and cause-specific risk of death in a large area-based cohort of very preterm infants. STUDY DESIGN: The ACTION (Accesso alle Cure e Terapie Intensive Ostetriche e Neonatali) study recruited during an 18-month period all infants 22-31 weeks' gestational age admitted to neonatal care in 6 Italian regions (n=3040). We analyzed the data of 2974 babies without lethal or acutely life-threatening malformations...
June 2013: Journal of Pediatrics
https://www.readbyqxmd.com/read/23033673/pandemic-influenza-a-h1n1-virus-in-a-swine-farm-house-in-sicily-italy
#12
A Guercio, G Purpari, P G Conaldi, V Pagano, A Moreno, P Giambruno, L Di Trani, G Vaccari, E Falcone, A Boni Istituto, P Cordioli
This report describes a pandemic A/H1N1 (H1N1 pdm) virus outbreak occurred in December, 2009 in a swine farm used as research facility (Istituto Mediterraneo Trapianti e Terapie ad Alta Specializzazione) for preclinical studies, located in Sicily, Italy. All the 13 pigs of the farm, showed cough, fever, inappetence and weakness. At the same time, an unvaccinated worker of the stabling showed influenza-like symptoms. RNAv extracted from two swabs collected from infected pigs resulted positive by Real Time RT-PCR for Influenza A virus...
March 2012: Journal of Environmental Biology
https://www.readbyqxmd.com/read/21798830/impact-of-recipients-socio-economic-status-on-patient-and-graft-survival-after-liver-transplantation-the-ismett-experience
#13
Salvatore Gruttadauria, Giuseppe Grosso, Antonio Mistretta, Duilio Pagano, Giovanni Scianna, Giovan Battista Vizzini, Davide Cintorino, Marco Spada, Francesco Basile, Bruno Gridelli
AIM: We aimed to determine whether education level and socioeconomic status in a cohort of liver transplant recipients in the south of Italy were potential predictors of graft and patient survival. METHODS: This retrospective study included 221 liver transplant recipients at Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione between January 2006 and September 2009. Donor gender and age, cold ischaemic time, extended criteria donors, recipient age, gender, body mass index, primary aetiology, Model for End-Stage Liver Disease score, co-morbidities, patient health score assessed on the basis of clinical follow-up, highest level of education achieved, and socioeconomic status were collected and analysed...
November 2011: Digestive and Liver Disease
https://www.readbyqxmd.com/read/21774708/abvd-versus-beacopp-for-hodgkin-s-lymphoma-when-high-dose-salvage-is-planned
#14
RANDOMIZED CONTROLLED TRIAL
Simonetta Viviani, Pier Luigi Zinzani, Alessandro Rambaldi, Ercole Brusamolino, Alessandro Levis, Valeria Bonfante, Umberto Vitolo, Alessandro Pulsoni, Anna Marina Liberati, Giorgina Specchia, Pinuccia Valagussa, Andrea Rossi, Francesco Zaja, Enrico M Pogliani, Patrizia Pregno, Manuel Gotti, Andrea Gallamini, Delia Rota Scalabrini, Gianni Bonadonna, Alessandro M Gianni
BACKGROUND: BEACOPP, an intensified regimen consisting of bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone, has been advocated as the new standard of treatment for advanced Hodgkin's lymphoma, in place of the combination of doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD). METHODS: We randomly assigned 331 patients with previously untreated and unfavorable Hodgkin's lymphoma (stage IIB, III, or IV, or an international prognostic score of ≥3 on a scale of 0 to 7, with higher scores indicating increased risk), to receive either BEACOPP or ABVD, each followed by local radiotherapy when indicated...
July 21, 2011: New England Journal of Medicine
https://www.readbyqxmd.com/read/21495410/-a-growing-problem-human-papillomavirus-and-head-and-neck-cancers
#15
REVIEW
Z Mechl, J Neuwirthová, D Brancíková
High-risk human papillomavirus (HPV) are implicated in the development of a subset of head and neck cancers, especially those arising from the lingual or palatine tonsils. HPV-associated cancer of the head and neck represent a different disease entity from those associated with the traditional risk factors of tobacco and alcohol use. There has been as increase in the annual incidence of HPV-related cancers in Europe and USA in the past years. It has now become clear that a subset of the head and neck tumors is a sexually transmitted disease with distinct pathogenesis and clinical and pathological features...
March 2011: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/21189387/risk-factors-for-the-development-of-secondary-malignancy-after-high-dose-chemotherapy-and-autograft-with-or-without-rituximab-a-20-year-retrospective-follow-up-study-in-patients-with-lymphoma
#16
MULTICENTER STUDY
Corrado Tarella, Roberto Passera, Michele Magni, Fabio Benedetti, Andrea Rossi, Angela Gueli, Caterina Patti, Guido Parvis, Fabio Ciceri, Andrea Gallamini, Sergio Cortelazzo, Valerio Zoli, Paolo Corradini, Alessandra Carobbio, Antonino Mulé, Marco Bosa, Anna Barbui, Massimo Di Nicola, Marco Sorio, Daniele Caracciolo, Alessandro M Gianni, Alessandro Rambaldi
PURPOSE: High-dose chemotherapy with peripheral blood progenitor cell (PBPC) autograft is effective in high-risk lymphoma, particularly with the addition of rituximab; however, it is associated with risk of secondary malignancy. These issues have been addressed in a series of 1,347 patients with lymphoma treated with a high-dose sequential (HDS) program. PATIENTS AND METHODS: A total of 1,024 patients with B-cell lymphoma, 234 patients with Hodgkin's lymphoma, and 89 patients with T-cell lymphoma were treated with HDS between 1985 and 2005 at 11 Gruppo Italiano Terapie Innovative Linfomi centers...
March 1, 2011: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/21166786/early-chemotherapy-intensification-with-beacopp-in-advanced-stage-hodgkin-lymphoma-patients-with-a-interim-pet-positive-after-two-abvd-courses
#17
MULTICENTER STUDY
Andrea Gallamini, Caterina Patti, Simonetta Viviani, Andrea Rossi, Francesca Fiore, Francesco Di Raimondo, Maria Cantonetti, Caterina Stelitano, Tatyana Feldman, Paolo Gavarotti, Roberto Sorasio, Antonino Mulè, Monica Leone, Alessandro Rambaldi, Alberto Biggi, Sally Barrington, Federico Fallanca, Umberto Ficola, Stéphane Chauvie, Alessandro Massimo Gianni
UNLABELLED: Interim 2-[18F]Fluoro-2-deoxy-D-glucose Positron Emission Tomography performed after two chemotherapy cycles (PET-2) is the most reliable predictor of treatment outcome in ABVD-treated Hodgkin Lymphoma (HL) patients. We retrospectively analysed the treatment outcome of a therapeutic strategy based on PET-2 results: positive patients switched to BEACOPP, while negative patients continued with ABVD. Between January 2006 and December 2007, 219 newly diagnosed HL patients admitted to nine centres were enrolled; 54 patients, unfit to receive this treatment were excluded from the analysis...
March 2011: British Journal of Haematology
https://www.readbyqxmd.com/read/20707053/oxidative-stress-hemoglobin-content-superoxide-dismutase-and-catalase-activity-influenced-by-sulphur-baths-and-mud-packs-in-patients-with-osteoarthritis
#18
Aleksandar Jokić, Nikola Sremcević, Zeki Karagülle, Tatjana Pekmezović, Vukosava Davidović
BACKGROUND/AIM: It is weel-known that sulphur baths and mud paks demonstrate beneficial effects on patients suffering from degenerative knee and hip osteoarthritis (OA) through the increased activity of protective antioxidant enzymes. The aim of this study was to assess lipid peroxidation level, i.e., malondialdehyde concetration, in individuals with knee and/or hip osteoarthritis (OA), as well as to determine the influence of sulphur baths and mud packs application on the activity of superoxide dismutase (SOD) and catalase (CAT) in order to minimize or eliminate excessive free radical species production (oxidative stress)...
July 2010: Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review
https://www.readbyqxmd.com/read/20201280/-stability-of-some-medicinal-solutions-with-captopril
#19
Silvia Imre, Szende Vancea, Daniela Lucia Muntean, Emese Sipos, Adela Cociş, Veronica Avrigeanu, Eleonora Mircia
UNLABELLED: The aim of the study was to investigate the stability of some oral liquid formulations containing 1 mg/ml captopril. MATERIAL AND METHOD: The oral solutions were prepared using captopril substance, keeping the formulation as simple as possible to avoid potentially undesirable excipients. Samples were stored for 39 days below 8 degrees C and at 22 +/- 3 degrees C and analysed for physical, chemical and microbiological stability. RESULTS: The formulations with ascorbic acid are stable for seven days either at 8 and 22 degrees C and could be prepared in hospital pharmacy as a more safely alternative to children terapy with tablets powders...
July 2008: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
https://www.readbyqxmd.com/read/19102211/-current-treatment-strategies-for-patients-with-cancers-of-the-head-and-neck
#20
REVIEW
Z Mechl, P Smilek, R Cervená
Head and neck squamous cell cancer (HNSCC) management is evolving rapidly. Approaches under exploration include induction chemotherapy, altered fractionation radiation with chemotherapy, intensity modulated radiation therapy (IMRT) and the use of biologically targeted drugs to enhance radiation. The goal of the new methods is improving the effectivity without increasing the toxicity. This article will focus maily on locally advanced HNSCC, which frequently remains a clinical challenge, review state-of-the-art therapy and introduce promising novel terapies...
2008: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
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