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myopia treatment

Alper Ağca, Ahmet Demirok, Yusuf Yıldırım, Ali Demircan, Dilek Yaşa, Ceren Yeşilkaya, İrfan Perente, Muhittin Taşkapılı
Small-incision lenticule extraction (SMILE) is an alternative to laser-assisted in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) for the correction of myopia and myopic astigmatism. SMILE can be performed for the treatment of myopia ≤-12 D and astigmatism ≤5 D. The technology is currently only available in the VisuMax femtosecond laser platform. It offers several advantages over LASIK and PRK; however, hyperopia treatment, topography-guided treatment, and cyclotorsion control are not available in the current platform...
2016: Clinical Ophthalmology
Kaori Kasahara, Muka Moriyama, Kei Morohoshi, Takeshi Yoshida, Noriaki Simada, Natsuko Nagaoka, Tae Yokoi, Kosei Shinohara, Yuichiro Kaneko, Mitsuki Suga, Kyoko Ohno-Matsui
PURPOSE: To investigate the 6-year outcome of intravitreal bevacizumab (IVB) to treat eyes with active choroidal neovascularization (CNV) due to pathologic myopia. METHODS: Medical records of 36 eyes of 35 consecutive patients with high myopia (refractive error ≥8 D or axial length ≥26.5 mm) and active CNV, who had been treated with IVB and followed for ≥6 years were analyzed. The factors that predicted the best-corrected visual acuity (BCVA) at 6 years after IVB were determined by multiple regression analyses...
October 10, 2016: Retina
Carlos A Medina, Angelica G Ortiz, Nidhi Relhan, William E Smiddy, Justin H Townsend, Harry W Flynn
PURPOSE: To report the clinical features, possible associations and treatment outcomes of patients with macular hole after pars plana vitrectomy (PPV) (single or multiple) for rhegmatogenous retinal detachment (RD). METHODS: Retrospective consecutive case series from July 2009 to July 2014. RESULTS: In the 15 study patients, the average time from RD surgery to macular hole diagnosis was 119 days (range: 41-398 months). Possible associations include epiretinal membrane (73%, 11/15 patients), macula-off RD (60%, 9/15 patients), recurrent RD (47%, 7/15 patients), and high myopia (56%, 5/9 patients)...
October 11, 2016: Retina
Sarah Moussa, Alois Dexl, Eva Maria Krall, Marie Dietrich, Eva-Maria Arlt, Günther Grabner, Josef Ruckhofer
PURPOSE: To evaluate and compare visual and refractive outcomes after laser-assisted in situ keratomileusis (LASIK) surgery for the correction of myopia or myopic astigmatism using 3 different treatment protocols. METHODS: We included 736 eyes of 369 patients (age 18-62 years) divided into 3 groups: 235 eyes of 118 patients (MEL80 group) undergoing LASIK using optimized aspheric ablation profiles (MEL80 excimer laser; Carl Zeiss Meditec), 248 eyes of 124 patients (Wavescan group) undergoing wavefront-guided (WFG) LASIK (STAR S4IR excimer laser + Wavescan aberrometer; Abbott Medical Optics), and 253 eyes of 127 patients (iDesign group) undergoing WFG LASIK (STAR S4IR excimer laser + iDesign system; Abbott Medical Optics)...
October 10, 2016: European Journal of Ophthalmology
Qianwen Gong, Miroslaw Janowski, Mingkun Xie, Guoyuan Yang, Longqian Liu
BACKGROUND: Genome-wide association studies of patients have linked the Rasgrf1 gene with myopia. The aim of this study was to investigate the messenger RNA (mRNA) expression of Rasgrf1 in the eyes of guinea pigs with induced myopia. METHODS: The myopia was induced by form deprivation in 24 guinea pigs, while additional 12 animals served as a control. Biometric measurements were used to monitor myopic progression. The animals were sacrificed at two, three and four weeks after beginning of the monocular form deprivation, followed by dissection of the retina, and the sclera, as well as mRNA isolation from both layers...
October 9, 2016: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
Sara Catalan-Lopez, Alba Mariña Portas-Ferradas, Luis Cadarso-Suarez, Adriana Rodriguez-Rodriguez
PURPOSE: To report the case of a residual refractive error after LASIK for moderate myopia successfully re-treated several years later using the small incision lenticule extraction (SMILE) technique. METHODS: Case report. RESULTS: Following LASIK, the patient showed a central flap thickness of 269 microns, whereas residual stromal bed thickness under the flap was 210 microns. SMILE was performed within the flap. In this less invasive surgical procedure, the residual stromal bed is not manipulated and ablation is conducted on the existing flap...
October 1, 2016: Journal of Refractive Surgery
Manli Liu, Jianchao Wang, Wen Zhong, Danyang Wang, Yugui Zhou, Quan Liu
PURPOSE: To evaluate the clinical results of suction loss in eyes during small incision lenticule extraction (SMILE). METHODS: This prospective paired-eye case study enrolled 8,490 eyes of 4,296 patients, of which 35 eyes experienced suction loss during the SMILE procedure while being treated for myopia or myopic astigmatism. The eyes with suction loss were re-treated with SMILE, femtosecond laser-assisted LASIK (FS-LASIK), or pseudo SMILE, and the fellow eyes were treated with SMILE...
October 1, 2016: Journal of Refractive Surgery
Tommy C Y Chan, Marco C Y Yu, Alex L K Ng, George P M Cheng, Jiamei Zhang, Yan Wang, Vishal Jhanji
PURPOSE: To analyze the visual and refractive outcomes of LASIK with and without simultaneous cross-linking for correction of myopia. METHODS: Patients who received femtosecond laser-assisted LASIK with and without adjunctive cross-linking according to patient's preference were examined longitudinally for 6 months. Patients with myopic manifest refraction spherical equivalent of 5.00 diopters (D) or greater and estimated residual stromal thickness of greater than 250 µm were included...
October 1, 2016: Journal of Refractive Surgery
Sarah J Bayless, Alistair J Harvey
The effect of alcohol intoxication on central and peripheral attention was examined as a test of Alcohol Myopia Theory (AMT). Previous research has supported AMT in the context of visual attention, but few studies have examined the effects of alcohol intoxication on central and peripheral attention. The study followed a 2 (alcohol treatment) × 2 (array size) × 2 (task type) mixed design. Forty-one participants (placebo or intoxicated) viewed an array of four or six colored circles, while simultaneously counting the flashes of a centrally presented fixation cross...
October 3, 2016: Perception
Arun Kumar Jain, Chintan Malhotra, Anand Pasari, Pawan Kumar, Majid Moshirfar
PURPOSE: To compare the outcomes of topography-guided and wavefront-optimized treatment in patients having laser in situ keratomileusis (LASIK) for myopia. SETTING: Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India. DESIGN: Prospective contralateral-eye case study. METHODS: Patients had topography-guided LASIK in 1 eye and wavefront-optimized LASIK in the contralateral eye using the Customized Refractive Surgery Master software and Mel 80 excimer laser...
September 2016: Journal of Cataract and Refractive Surgery
Ying Wu, Lei Tian, Li-Qiang Wang, Yi-Fei Huang
This was a prospective controlled clinical trial. 48 myopia patients (96 eyes) were included in this study. After LASIK, accelerated corneal collagen cross-linking (ACXL) was used for myopia treatment. During 6-month follow-up, the results of LASIK-ACXL treatment were studied and compared to the LASIK-only procedure. The results showed that no statistically significant differences in UDVA, CDVA, MRSE, K mean, pachymetry, or ECD were found between the two groups at the visit after 6 months of follow-up (all P > 0...
2016: BioMed Research International
N O'Keeffe, J Murphy, M O'Keefe, B Lanigan
We conducted a prospective randomized study to compare outcomes of intravitreal Bevacizumab versus diode laser in thirty eyes of fifteen premature babies with zone 1 or posterior zone 2 retinopathy of prematurity (ROP). We recorded complications, regression/reactivation of ROP, visual outcome, refractive error and systemic complications. The Bevacizumab treated eyes showed rapid regression of the ROP with resolution of plus disease and flattening of the ridge at 48 hours post injection. In 3 Bevacizumab treated eyes, reactivation occurred and were treated with laser (3 eyes) or a further Bevacizumab injection (1 eye)...
2016: Irish Medical Journal
S Taneri, S Kießler, A Rost, B Dick
Background: Small Incision Lenticule Extraction (SMILE) is a relatively new surgical method to correct myopia and myopic astigmatism. Although considered to be safe and effective, it is not yet popular. Potential reasons for its limited use could be that surgeons fear inferior results and a higher complication rate in the learning phase. Therefore we present our experiences with the treatment of our first 200 eyes, with special attention to refraction results, complications, and learning curve. Patients and Methods: 200 myopic or myopic astigmatic eyes of 102 patients were treated with SMILE...
September 19, 2016: Klinische Monatsblätter Für Augenheilkunde
Karen Hendler, Shiva Mehravaran, Xiang Lu, Stuart I Brown, Bartly J Mondino, Anne L Coleman
PURPOSE: To report the outcomes of full ophthalmic examination for preschool children in LA County who failed screening with the Retinomax Autorefractor. DESIGN: Retrospective, cross-sectional study. METHODS: Between August 2012 and May 2013, the University of California Los Angeles (UCLA) preschool vision program screened 11,260 preschool children aged 3-5 years in Los Angeles County using the Retinomax Autorefractor only. Of those, 1007 children who failed the screening were examined by an ophthalmologist on the UCLA Mobile Eye Clinic...
September 14, 2016: American Journal of Ophthalmology
Helena P Y Sin, Wilson W K Yip, Vesta C K Chan, Alvin L Young
The purpose of this study was to study the etiologies and operative outcomes of pediatric retinal detachment at a tertiary eye referral center in Hong Kong over a 10-year period. A retrospective study of patients (below 18 years of age) who received primary retinal detachment repair operations at a University Teaching Hospital between 2005 and 2015 was conducted. The study comprised 37 patients with 39 eyes affected who received primary retinal detachment (RD) surgery. Two patients had bilateral RD. 69.2 % were male...
September 14, 2016: International Ophthalmology
A Atili, E Singer, L Wörz, N Olschewski
Purpose: To evaluate a dose-response relationship by using Yokoyama procedure we compared a group of inhomogeneous cases with esohypotropia (EHT) associated with high myopia. Methods: We did a retrospective analysis of 7 cases with EHT associated with high myopia, who underwent Yokoyama procedure between 2014 and 2015. Pre- and postoperative orthoptic measurements as well as measurements of axial length were recorded. Results: The average age ranged from 59.5 ± 2.8 (SD) years. The mean value of axial lengths was 32...
September 13, 2016: Klinische Monatsblätter Für Augenheilkunde
Xiao Zhang, Xiang-Chen Tao, Zhi-Wei Li, Wei-Yan Zhou, Ping Ma, Chun-Xiao Zhang, Yu-Meng Wang, Guo-Ying Mu
The present study reports the use of a phakic toric Implantable Collamer Lens (ICL) that improved the refraction correction of high myopia and astigmatism in a case of keratectasia following corneal cross-linking. A 31-year-old male was diagnosed with keratectasia 12 years after laser-assisted in situ keratomileusis (LASIK). Following LASIK, the manifest refraction was -3.50-2.25×90 [0.1 logarithmic expression (LogMAR) best corrected visual acuity (BVCA)] in the right eye and -8.00-3.50×175 (0.3 LogMAR BCVA) in the left eye, with a LogMAR uncorrected distance visual acuity (UDVA) of 0...
September 2016: Experimental and Therapeutic Medicine
Alexandra Meidani, Chara Tzavara
PURPOSE: The main aim of this study was to compare the efficacy, safety, and predictability of femtosecond laser-assisted in situ keratomileusis performed by two different laser suites in the treatment of myopia for up to 6 months. METHODS: In this two-site retrospective nonrandomized study, myopic eyes that underwent laser-assisted in situ keratomileusis using IntraLase FS 60 kHz formed group 1 and those using WaveLight FS200 femtosecond laser system formed group 2...
2016: Clinical Ophthalmology
Philip Raey Kidd Turnbull, Oliver James Munro, John Robert Phillips
PURPOSE: A number of optical methods for slowing myopia progression have been tested and are now available. However, data on real-world use in clinical use is scarce. Here, we present a review of the clinical outcomes for patients attending a specialist myopia control clinic at The University of Auckland Optometry School, NZ. CASE SERIES: We report a comparative case series of 110 patients (aged 4-33 years, mean: 12.13 ± 4.58 years, 62% female) who attended the clinic between 2010 and 2014...
September 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
J Ding, K X Zhao, Y P Li, H Z Ma, X Chen, X Guo, L N Zhu, N D Li, W Zhang
OBJECTIVE: To study clinical characteristics and surgical treatment of idiopathic congenital nystagmus (ICN). METHODS: A retrospective study was conducted in 224 patients with ICN in Tianjin eye hospital from July 2007 to February 2013. RESULTS: There were 224 patients, 158 (70.54%) males and 66 (29.5%) females, mean age was (11.6±8.4) years and (11.4±6.4) years separately. Horizontal nystgamus happened in 215 cases, 3 cases were vertical type and 6 cases were mixed...
August 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
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