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https://www.readbyqxmd.com/read/29451636/-potentially-traumatic-events-and-post-traumatic-symptomatology-in-high-school-students
#1
Sheila Adriana Mendoza-Mojica, Octavio Márquez-Mendoza, Marcela Veytia-López, Luciana Esther Ramos-Lira, Ricardo Orozco-Zavala
OBJECTIVE: Describe the occurrence of potentially traumatic events (PTE) in high-school students, measure subthreshold post-traumatic symptomatology in those who still experience PTE repercussions and associate the symptomatology with sociodemographic and PTE characteristics. MATERIALS AND METHODS: Analytic transversal study carried out in a convenience sample of one thousand students from three high schools in the State of Mexico. The Scale for Post Traumatic Stress in University Students was applied...
November 2017: Salud Pública de México
https://www.readbyqxmd.com/read/29451418/patient-narratives-in-yelp-reviews-offer-insight-into-opioid-experiences-and-the-challenges-of-pain-management
#2
Rachel L Graves, Jesse Goldshear, Jeanmarie Perrone, Lyle Ungar, Elissa Klinger, Zachary F Meisel, Raina M Merchant
AIM: To characterize Yelp reviews about pain management and opioids. METHODS: We manually coded and applied natural language processing to 836 Yelp reviews of US hospitals mentioning an opioid medication. RESULTS: Yelp reviews by patients and caregivers describing experiences with pain management and opioids had lower ratings compared with other reviews. Negative descriptions of pain management and opioid-related experiences were more commonly described than positive experiences, and the number of themes they reflected was more diverse...
February 16, 2018: Pain Management
https://www.readbyqxmd.com/read/29450866/rehabilitative-orbital-decompression-for-graves-orbitopathy-results-of-a-randomized-clinical-trial
#3
S Sellari-Franceschini, R Rocchi, M Marinò, A Bajraktari, B Mazzi, G Fiacchini, P Lepri, I Dallan, P Vitti, C Marcocci
PURPOSE: Orbital decompression (OD) is a consolidated procedure for the treatment of exophthalmos in Graves' orbitopathy (GO). The efficacy of the various procedures remains unclear due to the variability of the techniques used. To address this issue, we performed a randomized clinical trial to compare the efficacy of two surgical techniques. The primary endpoint was the reduction in proptosis. Secondary aims were the risk of post-operative diplopia (POD) in primary gaze and other surgical complications...
February 15, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29449887/role-of-the-t-and-b-lymphocytes-in-pathogenesis-of-autoimmune-thyroid-diseases
#4
Marta Rydzewska, Michał Jaromin, Izabela Elżbieta Pasierowska, Karlina Stożek, Artur Bossowski
Autoimmune thyroid disorders (AITD) broadly include Graves' disease and Hashimoto's thyroiditis which are the most common causes of thyroid gland dysfunctions. These disorders develop due to complex interactions between environmental and genetic factors and are characterized by reactivity to self-thyroid antigens due to autoreactive lymphocytes escaping tolerance. Both cell-mediated and humoral responses lead to tissue injury in autoimmune thyroid disease. The differentiation of CD4+ cells in the specific setting of immune mediators (for example cytokines, chemokines) results in differentiation of various T cell subsets...
2018: Thyroid Research
https://www.readbyqxmd.com/read/29449198/a-rare-colonization-in-the-peritonitis-following-blunt-abdominal-trauma
#5
Oana Bulat, Cristian Bulat, Mihaela Blaj, Ioana Lupusoru, Viorel Scripcariu
BACKGROUND: Schewanella spp. is Gram-negative bacteria, saprophytes and rarely pathogenic. Initially isolated in 193, these belong to the marine environment; Schewanella (Pseudomonas) putrefaciens was found in water, soil and animal sources and produces hydrogen sulphide. Saccharomyces cerevisiae is the well-known yeast used for fermentation in industry and in molecular biology for research. In humans, it is a very rare pathogen which colonises the digestive tract and its utility has been linked to the treatment and prevention of diarrhoea associated with Clostridium difficile...
February 15, 2018: Balkan Medical Journal
https://www.readbyqxmd.com/read/29449175/study-of-pandrug-and-heavy-metal-resistance-among-e-coli-from-anthropogenically-influenced-delhi-stretch-of-river-yamuna
#6
Mudsser Azam, Arif Tasleem Jan, Ashutosh Kumar, Kehkashan Siddiqui, Aftab Hossain Mondal, Qazi Mohd Rizwanul Haq
Escalating burden of antibiotic resistance that has reached new heights present a grave concern to mankind. As the problem is no longer confined to clinics, we hereby report identification of a pandrug resistant Escherichia coli isolate from heavily polluted Delhi stretch of river Yamuna, India. E. coli MRC11 was found sensitive only to tobramycin against 21 antibiotics tested, with minimum inhibitory concentration values >256μg/mL for amoxicillin, carbenicillin, aztreonam, ceftazidime and cefotaxime. Addition of certain heavy metals at higher concentrations were ineffective in increasing susceptibility of E...
February 12, 2018: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/29448964/utility-of-rituximab-treatment-for-exophthalmos-myxedema-and-osteoarthropathy-syndrome-resistant-to-corticosteroids-due-to-graves-disease-a-case-report
#7
Aldo Ferreira-Hermosillo, Ruben Casados-V, Pedro Paúl-Gaytán, Victoria Mendoza-Zubieta
BACKGROUND: Exophthalmos, myxedema, and osteoarthropathy syndrome is a very rare condition that is associated with Graves' disease. The presence of dermopathy and the involvement of joint/bone tissues indicate that it seems to be related with the severity of the autoimmune process. Owing to its low incidence, there is a lack of information regarding its treatment and clinical follow-up. Some cases improved after use of high doses of steroids; however, some patients do not respond to this treatment...
February 16, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29445473/graves-disease-coexisting-with-resistance-to-thyroid-hormone-a-rare-case
#8
Hongping Sun, Shuhang Xu, Shaofeng Xie, Wen Cao, Guofang Chen, Hongjie Di, Rendong Zheng, Xingjia Li, Xiaodong Mao, Chao Liu
A rare case of resistance to thyroid hormone (RTH) complicated with Graves' hyperthyroidism was reported. The management of this disease is similar to that of Graves' disease. Antithyroid drug therapy is the first choice, and iodine therapy and surgery are not recommended due to the possibility of severe hypothyroidism and enlargement of the pituitary gland.
February 2018: Clinical Case Reports
https://www.readbyqxmd.com/read/29444549/body-weight-change-is-unpredictable-after-total-thyroidectomy
#9
Ron Glick, Paula Chang, Peter Michail, Jonathan W Serpell, Simon Grodski, James C Lee
BACKGROUND: There is a common perception that total thyroidectomy causes weight gain beyond expected age-related changes, even when thyroid replacement therapy induces a euthyroid state. The aim of this study was to determine whether patients who underwent total thyroidectomy for a wide spectrum of conditions experienced weight gain following surgery. METHODS: We retrospectively studied 107 consecutive total thyroidectomy patients treated between January 2013 and June 2014...
February 14, 2018: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29444089/evaluation-of-proctophyllodes-huitzilopochtlii-on-feathers-from-anna-s-calypte-anna-and-black-chinned-archilochus-alexandri-hummingbirds-prevalence-assessment-and-imaging-analysis-using-light-and-tabletop-scanning-electron-microscopy
#10
Youki K Yamasaki, Emily E Graves, Robin S Houston, Barry M OConnor, Patricia E Kysar, Mary H Straub, Janet E Foley, Lisa A Tell
Proctophyllodes huitzilopochtlii Atyeo & Braasch 1966 (Acariformes: Astigmata: Proctophyllodidae), a feather mite, was found on feathers collected from five hummingbird species in California. This mite has not been previously documented on feathers from Anna's (Calypte anna [Lesson 1829]) or Black-chinned (Archilochus alexandri [Bourcier & Mulsant 1846]) Hummingbirds. A total of 753 hummingbirds were evaluated for the presence of mites by species (Allen's n = 112; Anna's n = 500; Black-chinned n = 122; Rufous n = 18; Calliope n = 1), sex (males n = 421; females n = 329; 3 unidentified), and age (juvenile n = 199; after-hatch-year n = 549; 5 unidentified)...
2018: PloS One
https://www.readbyqxmd.com/read/29442060/thyroid-hemiagenesis-associated-with-multinodular-goiter-and-hashimoto-s-thyroiditis
#11
Daniela Bosco, A Cammarata, R Cannarella, R Latino, R Lanteri, A Di Cataldo, A Calogero
Thyroid hemiagenesis is a rare congenital abnormality in which one of the thyroid lobes is not developed. It can be associated with various thyroid diseases, such as Grave's disease, nodular goiter and thyroid neoplasm, rarely with hyperparathyroidism. We report a case of a 50-year old woman with left thyroid lobe agenesis diagnosed by ultrasonography and scintigraphy. Right thyroidectomy was performed and the histopathological examination showed diffuse hyperplasia, multinodular goiter and Hashimoto's thyroiditis...
November 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/29441423/how-do-mri-detected-subchondral-bone-marrow-lesions-bmls-on-two-different-mri-sequences-correlate-with-clinically-important-outcomes
#12
Siti Maisarah Mattap, Dawn Aitken, Karen Wills, Laura Laslett, Changhai Ding, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Stephen E Graves, Michelle Lorimer, Flavia Cicuttini, Graeme Jones
The aim of this study is to describe the association of bone marrow lesions (BMLs) present on two different MRI sequences with clinical outcomes, cartilage defect progression, cartilage volume loss over 2.7 years, and total knee replacement (TKR) over 13.3 years. 394 participants (50-80 years) were assessed at baseline and 2.7 years. BML presence at baseline was scored on T1-weighted fat-suppressed 3D gradient-recalled acquisition (T1) and T2-weighted fat-suppressed 2D fast spin-echo (T2) sequences. Knee pain, function, and stiffness were assessed using WOMAC...
February 13, 2018: Calcified Tissue International
https://www.readbyqxmd.com/read/29439614/effect-of-thyroglobulin-autoantibodies-on-the-metabolic-clearance-of-serum-thyroglobulin
#13
Francesco Latrofa, Debora Ricci, Sara Bottai, Federica Brozzi, Luca Chiovato, Paolo Piaggi, Michele Marino, Paolo Vitti
BACKGROUND: To establish whether thyroglobulin autoantibodies (TgAb) influence the metabolic clearance of thyroglobulin (Tg) in humans, we correlated serum Tg and TgAb shortly after 131I treatment. METHODS: Samples were collected from 30 consecutive patients undergoing 131I activity for Graves' hyperthyroidism at the time of treatment and every 15 days thereafter, up to 90 days. Tg and TgAb were measured by immunometric assays (functional sensitivities: 0.1 ng/mL and 8 IU/mL)...
February 14, 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29439598/diabetes-activates-periodontal-ligament-fibroblasts-via-nf-%C3%AE%C2%BAb-in-vivo
#14
J Zheng, S Chen, M L Albiero, G H A Vieira, J Wang, J Q Feng, D T Graves
Diabetes mellitus increases periodontitis and pathogenicity of the oral microbiome. To further understand mechanisms through which diabetes affects periodontitis, we examined its impact on periodontal ligament fibroblasts in vivo and in vitro. Periodontitis was induced by inoculation of Porphyromonas gingivalis and Fusobacterium nucleatum in normoglycemic and diabetic mice. Diabetes, induced by multiple low-dose injections of streptozotocin increased osteoclast numbers and recruitment of neutrophils to the periodontal ligament, which could be accounted for by increased CXC motif chemokine 2 (CXCL2) and receptor activator of nuclear factor kappa B ligand (RANKL) expression by these cells...
February 1, 2018: Journal of Dental Research
https://www.readbyqxmd.com/read/29439290/cell-death-nucleic-acids-and-immunity-inflammation-beyond-the-grave
#15
REVIEW
Keith B Elkon
Cells of the innate immune system are rigged with sensors that detect nucleic acids derived from microbes, especially viruses. It has become clear that these same sensors that respond to nucleic acids derived from damaged cells or defective intracellular processing are implicated in triggering diseases such as lupus and arthritis. The ways in which cells die and the concomitant presence of proteins and peptides that allow nucleic acids to re-enter cells profoundly influence innate immune responses. This review briefly discusses different types of programmed necrosis such as pyroptosis, necroptosis and NETosis and explains how nucleic acids can engage intracellular receptors and stimulate inflammation...
February 13, 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29435991/vagus-nerve-injury-symptoms-after-catheter-ablation-for-atrial-fibrillation
#16
Victoria Jacobs, Heidi T May, Brian G Crandall, Becca Ballantyne, Ben Chisum, Dave Johnson, Kevin G Graves, Michael Cutler, John D Day, Charles Mallender, Jeffrey S Osborn, J Peter Weiss, Thomas Jared Bunch
BACKGROUND: Vagus nerve injury during catheter ablation for atrial fibrillation (AF) can significantly impact quality of life and result in lingering gastrointestinal symptoms. This study was designed to define risk factors of vagal nerve injury, symptom prevalence and temporal resolution. METHODS: A total of 100 patients undergoing radiofrequency catheter ablation (RFCA) were enrolled and consented to participate in the study. Patients completed a 22 item questionnaire that included questions specific to vagus nerve injury symptomatology during their baseline visit and at 1 and 3 months post-RFCA...
February 13, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29435670/diagnostic-accuracy-of-a-new-fluoroenzyme-immunoassay-for-the-detection-of-tsh-receptor-autoantibodies-in-graves-disease
#17
Danilo Villalta, Federica D'Aurizio, Mirella Da Re, Debora Ricci, Francesco Latrofa, Renato Tozzoli
PURPOSE: Thyrotropin receptor (TSHR) autoantibodies (TRAbs) are a hallmark of Graves' disease (GD). The aim of this study was to evaluate the diagnostic accuracy of a new third generation automatic fluorescence enzyme immunoassay for TRAb measurement in GD, in comparison with two current IMAs. METHODS: Sera of 439 subjects (57 patients with untreated GD, 34 with treated GD, 15 with GD and Graves' orbitopathy, 52 with multinodular non-toxic goiter, 86 with Hashimoto's thyroiditis, 20 with toxic adenoma or toxic multinodular goiter, 55 with non-thyroid autoimmune diseases and 120 normal controls) were tested for TRAbs with the ELiA ™ anti-TSH-R assay (ThermoFischer Scientific, Uppsala, Sweden), the TRAK ™ RIA, Brahms (Thermo Scientific, Hennigsdorf, Germany) and the Immulite ™ TSI assay (Siemens Healthcare, Llanberis, UK)...
February 12, 2018: Auto- Immunity Highlights
https://www.readbyqxmd.com/read/29432270/what-is-the-long-term-survival-for-primary-tha-with-small-head-metal-on-metal-bearings
#18
Richard de Steiger, Andrea Peng, Peter Lewis, Stephen Graves
BACKGROUND: Large-head metal-on-metal (MoM) bearing hip replacements have been shown to have a much higher rate of revision than other bearing surfaces. However, small-head (≤ 32 mm) MoM bearing surfaces have been in use for many years with several reports of satisfactory mid- to long-term survivorship. It is unclear whether the long-term survival of small-head MoM devices will continue to be satisfactory or whether the same concerns seen with the large-head MoM devices will ultimately become more prevalent...
February 8, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29430505/role-of-radical-cystectomy-in-non-organ-confined-bladder-cancer-a-systematic-review
#19
Roger Li, Michael Metcalfe, Janet Kukreja, Neema Navai
Background: Currently, a diagnosis of non-organ confined bladder cancer (NOCBCa) confers a grave prognosis. The mainstay of treatment consists of systemic chemotherapy. However, it must be recognized that NOCBCa is a heterogeneous disease state with important clinical distinctions. While surgical extirpation has traditionally been regarded as overly aggressive for all NOCBCa patients, its utility as part of a multimodal treatment strategy in various clinical scenarios has not been thoroughly investigated...
January 20, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29428690/enteral-stents-in-the-management-of-post-bariatric-surgery-leaks
#20
Hany Shehab
A post-bariatric surgery leak is a rare but grave condition and remains every bariatric surgeon's nightmare. Endoscopic therapy with the insertion of self-expandable stents provides an effective minimally invasive approach for the management of leaks. Self-expandable stents, however, are still hampered by their tendency for migration and are not always well tolerated. Recently, double-pigtail stents have been proposed as an alternative endoscopic therapeutic modality. Both types of stents have been shown to be very effective in the management of leaks; however, most studies have pooled gastrointestinal leaks due to different etiologies together...
December 16, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
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