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https://www.readbyqxmd.com/read/27936467/clinical-relevance-of-cell-free-dna-in-gastrointestinal-tract-malignancy
#1
Yuan-Tzu Lan, Ming-Huang Chen, Wen-Liang Fang, Chih-Cheng Hsieh, Chien-Hsing Lin, Fang-Yu Jhang, Shung-Haur Yang, Jen-Kou Lin, Wei-Shone Chen, Jeng-Kai Jiang, Pei-Ching Lin, Shih-Ching Chang
BACKGROUND: Cell-free DNA (cfDNA) extracted from blood has become a clinically feasible biomarker in various types of cancer. However, the clinical significance of cfDNA in gastrointestinal (GI) tract cancer among Asian populations requires further investigation. RESULTS: The median cfDNA copy number was highest in esophageal cancer, followed by colorectal cancer and gastric cancer, which were all significantly higher than those of healthy individuals. The cfDNA levels were higher in GI tract cancer, followed by those in carcinoma in situ and then healthy individuals (P = 0...
December 7, 2016: Oncotarget
https://www.readbyqxmd.com/read/27931023/increased-need-for-gastrointestinal-surgery-and-increased-risk-of-surgery-related-complications-in-patients-with-ehlers-danlos-syndrome-a-systematic-review
#2
Marie-Louise Kulas Søborg, Julie Leganger, Jacob Rosenberg, Jakob Burcharth
BACKGROUND/AIMS: Ehlers-Danlos syndromes (EDSs) constitute a rare group of inherited connective tissue diseases, characterized by multisystemic manifestations and general tissue fragility. Most severe complications include vascular and gastrointestinal (GI) emergencies requiring acute surgery. The purpose of this systematic review was to assess the causes of GI-related surgery and related mortality and morbidity in patients with EDSs. METHODS: A systematic search was conducted in PubMed, Embase, and Scopus to identify relevant studies...
December 9, 2016: Digestive Surgery
https://www.readbyqxmd.com/read/27927033/effects-of-lateral-electrical-surface-stimulation-on-scoliosis-in-children-with-severe-cerebral-palsy-a-pilot-study
#3
Eun Jae Ko, In Young Sung, Gi Jeong Yun, Jung-A Kang, JaYoung Kim, Go Eun Kim
PURPOSE: To evaluate the effects of lateral electrical surface stimulation (LESS) on scoliosis and trunk balance in children with severe cerebral palsy (CP). METHODS: Children with severe CP (GMFCS level IV or V) and stationary or progressive scoliosis were enrolled. Children were recommended of two sessions of LESS/day, 1 h/session, for 3 months at home: at 40-80 mA intensity, 200 μs pulse width, 25 Hz frequency, on for 6 s and then off for 6 s on the convex side of the trunk curve...
December 7, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27925557/-don-t-be-afraid-of-failure
#4
(no author information available yet)
Venetia Wynter-Blyth has worked in oncology for 15 years. She spent 12 years as an upper gastrointestinal (GI) clinical nurse specialist before taking up her current post as Macmillan nurse consultant in upper GI cancers at Imperial College Healthcare NHS Trust in London. She was named RCN Nurse of the Year 2016 for creating PREPARE, a holistic 'prehabilitation' self-management programme for people with cancer who require surgery.
December 7, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27913718/longitudinal-voice-outcomes-after-type-i-gore-tex-thyroplasty-for-nonparalytic-glottic-incompetence
#5
Lewis Overton, Katherine Adams, Rupali N Shah, Robert A Buckmire
OBJECTIVE: Type I Gore-tex thyroplasty (GTP) for nonparalytic glottic incompetence (GI) results in significantly improved subjective and perceptual voice outcomes. We endeavored to investigate the longitudinal course of voice outcomes measuring the same patients across time points stratified by diagnostic subgroup. METHODS: Seventy-five patients with nonparalytic GI treated with GTP in the past 9 years were retrospectively reviewed and grouped according to their primary diagnoses (atrophy, scar, hypomobility, and paresis)...
January 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/27905087/robot-assisted-surgery-in-elderly-and-very-elderly-population-our-experience-in-oncologic-and-general-surgery-with-literature-review
#6
Graziano Ceccarelli, Enrico Andolfi, Alessia Biancafarina, Aldo Rocca, Maurizio Amato, Marco Milone, Marta Scricciolo, Barbara Frezza, Egidio Miranda, Marco De Prizio, Andrea Fontani
BACKGROUND: Although there is no agreement on a definition of elderly, commonly an age cutoff of ≥65 or 75 years is used. Nowadays most of malignancies requiring surgical treatment are diagnosed in old population. Comorbidities and frailty represent well-known problems during and after surgery in elderly patients. Minimally invasive surgery offers earlier postoperative mobilization, less blood loss, lower morbidity as well as reduction in hospital stay and as such represents an interesting and validated option for elderly population...
November 30, 2016: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/27889271/assessment-of-perioperative-nutrition-practices-and-attitudes-a-national-survey-of-colorectal-and-gi-surgical-oncology-programs
#7
J D Williams, Paul E Wischmeyer
BACKGROUND: Implementation of evidence-based peri-operative nutrition in the U.S. is poorly described and hypothesized to be suboptimal. This study broadly describes practices and attitudes regarding nutrition screening/intervention in U.S. gastrointestinal and oncologic surgeons. METHODS: Nationwide nutritional practice survey of GI/Oncologic surgical faculty. RESULTS: Program response rates were 57% and 81% for colorectal and oncology fellowships, respectively...
November 17, 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27875849/-short-and-long-term-results-in-operable-pancreatic-ductal-adenocarcinomas-from-a-cooperation-between-two-departments-gastroenterology-visceral-surgery-at-non-university-hospitals-benchmarked-to-results-of-expert-centers
#8
W Dippold, V Sivanathan, K Statt, M Roitman, K H Link
The only curative approach in pancreatic ductal adenocarcinoma (PDAC) is resection, which is possible only in 15 - 30 % of patients. Local tumor spread or distant metastases are contraindications for resection in the majority of patients. Surgical-oncological quality with short- and long-term results are varying tremendously, so that "expertise/quality" are associated to hospital- or surgeon's volume and/or center formation. The treatment results also depend, to a great extent, on the medical diagnostic quality...
November 22, 2016: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/27857916/the-effectiveness-of-subdural-drains-using-urokinase-after-burr-hole-evacuation-of-subacute-subdural-hematoma-in-elderly-patients-a-prelimilary-report
#9
Chang-Gi Yeo, Woo-Yeol Jeon, Seong-Ho Kim, Oh-Lyong Kim, Min-Su Kim
OBJECTIVE: A subdural drain using urokinase after a burr hole hematoma evacuation was performed for subacute subdural hematoma (SASDH), and its effectiveness and safety in elderly patients were evaluated. METHODS: Between January 2013 and May 2015, subdural drains using urokinase after burr hole hematoma evacuation were performed in 19 elderly patients. The inclusion criteria were as follows: 1) a subdural hematoma occurring between 4 and 20 days after injury; 2) worsening neurological symptoms, from mild to moderate or severe, due to injury during the subacute stage; 3) a mix of solid clots (high-density lighter shadow) and fluid hematoma (low-density darker shadow) on the computed tomography (CT) scan; 4) a score of ≥9 on the Glasgow Coma Scale (GCS) assessed immediately before surgery; and 5) an age of ≥65 years...
October 2016: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/27844452/urgency-surgical-treatment-for-duodenal-gists-analysis-of-aged-patients-and-review-of-the-literature
#10
Carlo Boselli, Roberto Cirocchi, Alessandro Gemini, Francesco Barberini, Veronica Grassi, Stefano Avenia, Andrea Polistena, Alessandro Sanguinetti, Daniele Pironi, Alberto Santoro, Renata Tabola, Nicola Avenia
INTRODUCTION: Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal neoplasms (85%) of the gastrointestinal (GI) tract; duodenal GISTs constitute 3-5% of all GISTs and represent 10-30% of all malignant tumours of the duodenum. Rarely, patients present severe bowel obstruction, perforation or severe bleeding. The radical resection with complete removal of the tumour remains the main therapeutic approach. We performed a local resection in patients with suspected GIST admitted for emergency treatment for GI bleeding...
November 14, 2016: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/27837291/the-psychosocial-impact-of-undergoing-prophylactic-total-gastrectomy-ptg-to-manage-the-risk-of-hereditary-diffuse-gastric-cancer-hdgc
#11
Nina Hallowell, Julia Lawton, Shirlene Badger, Sue Richardson, Richard H Hardwick, Carlos Caldas, Rebecca C Fitzgerald
Individuals identified as at high risk of developing Hereditary Diffuse Gastric Cancer (HDGC) are advised to undergo prophylactic surgery - have their stomach removed - in their early twenties. Research with (older) cancer patients who undergo gastrectomy for curative reasons suggests that gastric resection has a number of physical and psychosocial sequelae. Because it is difficult to extrapolate the findings of studies of older cancer patients to younger healthy patients who are considering prophylactic total gastrectomy (PTG), the aim of this qualitative interview study was to determine the psychosocial implications of undergoing prophylactic surgery to manage genetic risk...
November 11, 2016: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/27834008/severe-gastrointestinal-haemorrhage-summary-of-a-national-quality-of-care-study-with-focus-on-radiological-services
#12
Simon J McPherson, Martin T Sinclair, Neil C E Smith
PURPOSE OF STUDY: To identify the remediable factors in the quality of care provided to patients with severe gastrointestinal (GI) bleeding. METHOD: All hospital admissions in the first four months of 2013 with ICD10 coding for GI bleeding who received a transfusion of 4 units or more of blood. Up to five cases/hospital randomly selected for structured case note peer review. National availability of GI bleeding services data derived from organisational questionnaire completed by all hospitals...
November 10, 2016: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/27830139/advantages-of-intraoral-and-transconjunctival-approaches-for-posterior-displacement-of-a-fractured-zygomaticomaxillary-complex
#13
Ji Yong Yoo, Jang Won Lee, Seung Jae Paek, Won Jong Park, Eun Joo Choi, Kyung-Hwan Kwon, Moon-Gi Choi
BACKGROUND: Fracture of the zygomaticomaxillary complex (ZMC) is one of the most common facial injuries. A previous study has performed 3D analyses of the parallel and rotational displacements that occur in a fractured ZMC. However, few studies have investigated adequate fixation methods according to these displacements. Here, we assessed whether specific approaches and fixation methods for displacement of ZMC fractures produce esthetic results. METHODS: Hospital records and pre- and post-surgical computed tomographic scans of patients treated for ZMC fractures at the Department of Oral and Maxillofacial Surgery, College of Dentistry, Wonkwang University, between January 2010 and December 2015, were selected...
December 2016: Maxillofacial Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27822725/enhanced-recovery-after-surgery-programs-improve-patient-outcomes-and-recovery-a-meta-analysis
#14
Christine S M Lau, Ronald S Chamberlain
INTRODUCTION: Enhanced recovery after surgery (ERAS) programs have been developed to improve patient outcomes, accelerate recovery after surgery, and reduce healthcare costs. ERAS programs are a multimodal approach, with interventions during all stages of care. This meta-analysis examines the impact of ERAS programs on patient outcomes and recovery. METHODS: A comprehensive search of all published randomized control trials (RCTs) assessing the use of ERAS programs in surgical patients was conducted...
November 7, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27811622/therapeutic-endoscopy-for-the-control-of-non-variceal-upper-gastrointestinal-bleeding-in-children-a-case-series
#15
Anna M Banc-Husu, Nuzhat A Ahmad, Vinay Chadrasekhara, Gregory G Ginsberg, David L Jaffe, Michael L Kochman, Michael Rajala, Petar Mamula
INTRODUCTION: Gastrointestinal bleeding is one of the most common indications for urgent endoscopy in the pediatric setting. The majority of these procedures are performed for control of variceal bleeding, with very few performed for non-variceal upper gastrointestinal (NVUGI) bleeding. The data on therapeutic endoscopy for NVUGI are very sparse. The aims of our study were to review our experience with NVUGI bleeding, describe technical aspects and outcomes of therapeutic endoscopy, and determine gastroenterology fellows' training opportunities according to the national training guidelines...
November 2, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27806030/a-morbidity-mortality-analysis-of-a-tertiary-level-upper-gastrointestinal-hepatopancreaticobiliary-surgical-unit
#16
Susrutha K Wickremesekera, Ho Beom Sean Seo, Mary Anne Trimber, Simon Bann, Katherine Tse
: Internationally, regionalisation of major upper gastrointestinal/hepatopancreaticobiliary (UGI/HPB) surgery to a selected number of expert hospital centres has demonstrated that high hospital volume is associated with lower mortality and morbidity. The Wellington UGI/HPB unit compared to international institutions is a low volume unit, however within New Zealand we perform a high number of Upper GI/HPB cases. AIMS: The aim of this study was to evaluate the quality measures of morbidity and mortality of major upper gastrointestinal and hepatopancreatobiliary surgeries performed at the Wellington UGI/HPB unit...
October 28, 2016: New Zealand Medical Journal
https://www.readbyqxmd.com/read/27805997/this-too-shall-pass-a-study-of-ingested-sharp-foreign-bodies
#17
Kirellos R Zamary, James W Davis, Emily E Ament, Rachel C Dirks, John E Garry
BACKGROUND: Gastrointestinal foreign body (GFB) ingestion is a common problem and often results in surgical consultation. Current literature is limited to case reports and fails to provide data regarding the management of sharp GFB ingestion. We hypothesized that patients who ingest sharp objects rarely have perforation or obstruction requiring surgical intervention. METHODS: Patients presenting with GFBs from 1/05-12/15 at a level 1 trauma center with an acute care surgery program were retrospectively reviewed...
October 31, 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27799988/three-years-outcome-of-microdiscectomy-via-paramedian-approach-for-lumbar-foraminal-or-extraforaminal-disc-herniations-in-elderly-patients-over-65-years-old
#18
Chang Gi Yeo, Ikchan Jeon, Sang Woo Kim, Sam Kyu Ko, Byung Kil Woo, Kwang Chul Song
OBJECTIVE: Lumbar foraminal or extraforaminal disc herniations (FEFDH) have unusual clinical features and higher incidence in elderly patients compared to usual intraspinal canal disc herniations. We evaluated the efficacy of microdiscectomy via paramedian approach for lumbar FEFDH in elderly patients over the age of 65. METHODS: Retrospective study was performed in 68 patients over the age of 65 (23 male and 45 female patients; 71.46±3.87 years) who underwent microdiscectomy via paramedian approach for unilateral lumbar FEFDH causing sciatica...
September 2016: Korean Journal of Spine
https://www.readbyqxmd.com/read/27793547/-clinical-trial-with-educational-intervention-in-perimenopausal-women-with-cardiovascular-risk-factor
#19
Anxela Soto-Rodríguez, José Luís García-Soidán, Manuel de Toro-Santos, Manuel Rodríguez-González, M Jesús Arias-Gómez, María Reyes Pérez-Fernández
OBJECTIVE: To assess whether an educational intervention in women in perimenopausal age with diabetes mellitus, hypertension and/or dyslipidemia could improve aspects of quality of life and exercise. METHODS: A randomized clinical trial. VARIABLES: physical activity, quality of life and weight in women aged 45-60 years (n = 320) at time 0 and 12 months after surgery. intervention group (IG): 3 interactive workshops on cardiovascular disease prevention and control group (CG): information by mail...
October 25, 2016: Gaceta Sanitaria
https://www.readbyqxmd.com/read/27792104/neurocutaneous-melanosis-presenting-as-cavernous-hemangioma-persistent-abdominal-pain
#20
Keman Liao, Shuanglin Que, Yongming Qiu, Shilei Zhang, Zhihua Chen
Neurocutaneous melanosis (NCM) is a rare congenital syndrome characterized by the presence of multiple congenital melanocytic nevi and the proliferation of melanocytes in the central nervous system. The authors present a 9-year-old Chinese boy whose clinical manifestations are intermittent headache for 2 months and persistent abdominal pain for 10 days. 3D-reconstruction computed tomography angiography image, digital subtraction angiography, and magnetic resonance imaging plus angiography (MRI+MRA) examinations results suggested that cavernoma at left frontal lobe potentially associated with hemorrhage...
October 27, 2016: Journal of Craniofacial Surgery
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