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https://www.readbyqxmd.com/read/28106365/coordinatively-self-assembled-luminescent-gold-nanoparticles-fluorescence-turn-on-system-for-high-efficiency-passive-tumor-imaging
#1
Xuandi Lai, Lishan Tan, Xiulong Deng, Jinbin Liu, Aiqing Li, Jianyu Liu, Jianqiang Hu
A fluorescence turn-on system for highly efficient and prolonged tumor imaging has been established by Co2+-induced coordination self-assembly strategy, in which luminescent glutathione (GSH)-modified gold nanoparticles (LGAuNPs) are assembled into LGAuNPs assemblies (LGAuNPs-Co) through coordination bond between unoccupied orbit of Co2+ and lone pair electrons of GSH on the surface of LGAuNPs. The LGAuNPs-Co is sensitive to microenvironment pH and its quenched luminescence will be turned on in tumor tissues (acidic microenvironment), which behaves as a fluorescence turn-on system for passive tumor imaging...
January 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28105585/how-feasible-is-multiple-time-point-web-based-data-collection-with-individuals-experiencing-street-homelessness
#2
Karin M Eyrich-Garg, Shadiya L Moss
Three barriers investigators often encounter when conducting longitudinal work with homeless or other marginalized populations are difficulty tracking participants, high rates of no-shows for follow-up interviews, and high rates of loss to follow-up. Recent research has shown that homeless populations have substantial access to information technologies, including mobile devices and computers. These technologies have the potential both to make longitudinal data collection with homeless populations easier and to minimize some of these methodological challenges...
January 19, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28104595/frailty-affects-the-initial-treatment-response-and-time-to-recovery-of-mobility-in-acutely-ill-older-adults-admitted-to-hospital
#3
Oliver L Hatheway, Arnold Mitnitski, Kenneth Rockwood
OBJECTIVES: to investigate how frailty and mobility impairment affect recovery of balance and mobility in acutely ill older patients. DESIGN: secondary analysis of cohort study. SETTING: general and geriatric medicine inpatient units, QEII Health Sciences Centre, Dalhousie University, Canada. SUBJECTS: four hundred and nine older adults (mean age = 81 ± 7 standard deviation, 64% women). METHODS: we constructed a frailty index based on a comprehensive geriatric assessment (FI-CGA), at baseline (2 weeks before admission; mean 0...
January 18, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28103427/repeated-maximal-intensity-hypoxic-exercise-superimposed-to-hypoxic-residence-boosts-skeletal-muscle-transcriptional-responses-in-elite-team-sport-athletes
#4
Franck Brocherie, Grégoire P Millet, Gommaar D'Hulst, Ruud Van Thienen, Louise Deldicque, Olivier Girard
AIM: To determine whether repeated maximal-intensity hypoxic exercise induces larger beneficial adaptations on the hypoxia inducible factor-1α pathway and its target genes than similar normoxic exercise, when combined with chronic hypoxic exposure. METHODS: Lowland elite male team-sport athletes underwent 14 days of passive normobaric hypoxic exposure (≥14 h.day(-1) at Fi O2 14.5-14.2%) with the addition of six maximal-intensity exercise sessions either in normobaric hypoxia (Fi O2 ~14...
January 19, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/28098772/a-non-intrusive-cyber-physical-social-sensing-solution-to-people-behavior-tracking-mechanism-prototype-and-field-experiments
#5
Yunjian Jia, Zhenyu Zhou, Fei Chen, Peng Duan, Zhen Guo, Shahid Mumtaz
Tracking people's behaviors is a main category of cyber physical social sensing (CPSS)-related people-centric applications. Most tracking methods utilize camera networks or sensors built into mobile devices such as global positioning system (GPS) and Bluetooth. In this article, we propose a non-intrusive wireless fidelity (Wi-Fi)-based tracking method. To show the feasibility, we target tracking people's access behaviors in Wi-Fi networks, which has drawn a lot of interest from the academy and industry recently...
January 13, 2017: Sensors
https://www.readbyqxmd.com/read/28096651/effects-of-3-diquafosol-sodium-ophthalmic-solution-on-higher-order-aberrations-in-patients-diagnosed-with-dry-eye-after-cataract-surgery
#6
Yasushi Inoue, Shintarou Ochi
PURPOSE: To evaluate the effects of diquafosol sodium ophthalmic solution 3% (DQS) and artificial tears (AT) on higher-order aberrations (HOAs) in patients with dry eye after cataract surgery. DESIGN: This was a post hoc analysis of a previously conducted randomized clinical study. METHODS: Fifty-nine eyes from 42 patients (17 males and 25 females, aged 72.6±8.0 years) with verified or suspected dry eye at 4 weeks after cataract surgery were evaluated...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28094488/effects-of-leg-contrast-strength-training-on-sprint-agility-and-repeated-change-of-direction-performance-in-male-soccer-players
#7
Mehréz Hammami, Yassine Negra, Roy J Shephard, Mohamed Souhaiel Chelly
BACKGROUND: Contrast training is popular technique among individuals who are involved in dynamic sports, having as its goal an increase in dynamic muscular performance. It is characterized by the use of high and low loads in the same strength training session. The present investigation aimed to determine the effects of adding 8--weeks of contrast strength training (CSTP) to regular soccer practice in U--17 male soccer players during the competitive season. We hypothesized that CSTP would enhance their performance...
January 17, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28093766/psychometric-evaluation-of-the-sex-after-myocardial-infarction-knowledge-test-in-iranian-context
#8
Hossein Asgar Pour, Mohammad Reza Heidari, Reza Norouzzadeh, Fardin Rahimi, Anoshirvan Kazemnejad, Faramarz Fallahi
PURPOSE: To translate, adapt, and assess the psychometric properties of the Sex After MI Knowledge Test in Iranian context (where MI is myocardial infarction). DESIGN AND METHODS: A cross-sectional descriptive survey was performed. The sample comprised 250 patients with MI. Confirmatory factor analysis was applied to extract three indicators. FINDINGS: The Sex After MI Knowledge Test indicated good reproducibility (Cronbach's α = .76, Intraclass correlation (ICC) = 0...
January 16, 2017: Perspectives in Psychiatric Care
https://www.readbyqxmd.com/read/28093025/a-fuzzy-integral-method-based-on-the-ensemble-of-neural-networks-to-analyze-fmri-data-for-cognitive-state-classification-across-multiple-subjects
#9
L A Cacha, S Parida, S Dehuri, S-B Cho, R R Poznanski
The huge number of voxels in fMRI over time poses a major challenge to for effective analysis. Fast, accurate, and reliable classifiers are required for estimating the decoding accuracy of brain activities. Although machine-learning classifiers seem promising, individual classifiers have their own limitations. To address this limitation, the present paper proposes a method based on the ensemble of neural networks to analyze fMRI data for cognitive state classification for application across multiple subjects...
January 17, 2017: Journal of Integrative Neuroscience
https://www.readbyqxmd.com/read/28092407/study-of-potential-health-effects-of-electromagnetic-fields-of-telephony-and-wi-fi-using-chicken-embryo-development-as-animal-model
#10
Henri Woelders, Agnes de Wit, Alexander Lourens, Norbert Stockhofe, Bas Engel, Ina Hulsegge, Dirkjan Schokker, Paula van Heijningen, Stefan Vossen, Dave Bekers, Peter Zwamborn
The objective of this study is to investigate possible biological effects of radiofrequency electromagnetic fields (RF-EMF) as used in modern wireless telecommunication in a well-controlled experimental environment using chicken embryo development as animal model. Chicken eggs were incubated under continuous experimental exposure to GSM (1.8 GHz), DECT (1.88 GHz), UMTS (2.1 GHz), and WLAN (5.6 GHz) radiation, with the appropriate modulation protocol, using a homogeneous field distribution at a field strength of approximately 3 V/m, representing the maximum field level in a normal living environment...
January 16, 2017: Bioelectromagnetics
https://www.readbyqxmd.com/read/28090140/influence-of-warm-up-duration-and-recovery-interval-prior-to-exercise-on-anaerobic-performance
#11
M Frikha, N Chaâri, N Mezghanni, N Souissi
The purpose of the study was to determine the impact of different active warm-up (AWU) durations and the rest interval separating it from exercise on anaerobic performance. Eleven male physical education students (22.6 ± 2.52 years; 179.2 ± 4.3 cm; 82.5 ± 9.7 kg; mean ± SD) participated in a cross-over randomized study, and they all underwent the Wingate test after three AWU durations: 5 min (AWU5), 15 min (AWU15) and 20 min (AWU20), with recovery (WREC) or without a recovery interval (NREC) separating the AWU and anaerobic exercise performance...
December 2016: Biology of Sport
https://www.readbyqxmd.com/read/28089506/evaluation-of-the-predictive-value-of-placental-vascularisation-indices-derived-from-3-dimensional-power-doppler-whole-placental-volume-scanning-for-prediction-of-pre-eclampsia-a-systematic-review-and-meta-analysis
#12
K A Eastwood, C Patterson, A J Hunter, D R McCance, I S Young, V A Holmes
Pre-eclampsia remains a leading cause of maternal and fetal morbidity and mortality. This systematic review aims to evaluate the ability of placental vascularisation indices (PVIs) derived from 3D power Doppler whole placental volume scanning to predict early, late and any-onset pre-eclampsia (PE). The following databases were searched: MEDLINE, EMBASE and Web of Science. Studies selected for inclusion measured PVIs: Vascularisation Index (%) (VI) and/or Flow Index (FI) and/or Vascularisation Flow Index (VFI) derived from 3D power Doppler whole placental volume scanning via Virtual Organ Computer-aided Analysis (VOCAL) technique prior to diagnosis of PE...
January 5, 2017: Placenta
https://www.readbyqxmd.com/read/28087395/lumbar-spinal-muscles-and-spinal-canal-study-by-mri-three-dimensional-reconstruction-in-adult-lumbar-spinal-stenosis
#13
Louis Boissière, Bertrand Moal, Olivier Gille, Elise De-Roquefeuil, Muriel Durieux, Ibrahim Obeid, Vincent Dousset, Jean-Marc Vital, Wafa Skalli
BACKGROUND: Lumbar spinal stenosis is degenerative disc disease most common manifestation. If stenosis degree seems poorly related to symptom severity, lumbar muscles role is recognized. Many studies report imaging methods, to analyze muscle volumes and fat infiltration (FI), but remain limited due to the difficulty to represent entire muscle volume variability. Recently a 3D muscle reconstruction protocol (using the deformation of a parametric specific object method (DPSO) and three point Dixon images) was reported...
January 10, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28078841/differential-expression-and-distribution-of-cytokeratins-and-vimentin-in-buccal-pouch-mucosal-cells-during-real-time-cell-proliferation-research-based-on-a-porcine-model
#14
A Bryja, M Dyszkiewicz-Konwińska, A Chachuła, S Ciesiółka, W Kranc, D Bukowska, P Antosik, M Bruska, M Nowicki, M Zabel, B Kempisty
In recent years, buccal pouch oral mucosa cells were used as a source of potential biological grafting material in advanced tissue engineering. However, there are several limitations in the process of graft fabrication: donor and recipient patient availability as well as an incomplete knowledge of in vitro procedures related to tissue surgical recovery, in vitro cell culture (IVC) and/or tissue processing in “human somatic cell therapy.” Therefore, the animal model for oral mucosa grafting is still recognized as a source for xenografts and a useful model for biomedical research...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28074013/exposure-to-radiofrequency-electromagnetic-fields-from-wi-fi-in-australian-schools
#15
Ken Karipidis, Stuart Henderson, Don Wijayasinghe, Lydiawati Tjong, Rick Tinker
The increasing use of Wi-Fi in schools and other places has given rise to public concern that the radiofrequency (RF) electromagnetic fields from Wi-Fi have the potential to adversely affect children. The current study measured typical and peak RF levels from Wi-Fi and other sources in 23 schools in Australia. All of the RF measurements were much lower than the reference levels recommended by international guidelines for protection against established health effects. The typical and peak RF levels from Wi-Fi in locations occupied by children in the classroom were of the order of 10(-4) and 10(-2)% of the exposure guidelines, respectively...
January 10, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/28069635/evaluating-approaches-to-find-exon-chains-based-on-long-reads
#16
Anna Kuosmanen, Tuukka Norri, Veli Mäkinen
: Transcript prediction can be modeled as a graph problem where exons are modeled as nodes and reads spanning two or more exons are modeled as exon chains. Pacific Biosciences third-generation sequencing technology produces significantly longer reads than earlier second-generation sequencing technologies, which gives valuable information about longer exon chains in a graph. However, with the high error rates of third-generation sequencing, aligning long reads correctly around the splice sites is a challenging task...
January 9, 2017: Briefings in Bioinformatics
https://www.readbyqxmd.com/read/28065754/mechanisms-involved-in-antinociception-induced-by-a-polysulfated-fraction-from-seaweed-gracilaria-cornea-in-the-temporomandibular-joint-of-rats
#17
Chistiane Oliveira Coura, Hellíada Vasconcelos Chaves, Danielle Rocha do Val, Lorena Vasconcelos Vieira, Felipe Dantas Silveira, Fernanda Maxcynne Lino Dos Santos Lopes, Francisco Isaac Fernandes Gomes, Annyta Fernandes Frota, Ricardo Basto Souza, Juliana Trindade Clemente-Napimoga, Mirna Marques Bezerra, Norma Maria Barros Benevides
Temporomandibular disorder is a common clinical condition involving pain in the temporomandibular joint (TMJ) region. This study assessed the antinociceptive effects of a polysulfated fraction from the red seaweed Gracilaria cornea (Gc-FI) on the formalin-induced TMJ hypernociception in rats and investigated the involvement of different mechanisms. Male Wistar rats were pretreated with injection (sc) of saline or Gc-FI 1h before intra- TMJ injection of formalin to evaluate the nociception. The results showed that pretreatment with Gc-FI significantly reduced formalin-induced nociceptive behavior...
January 5, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28058746/multidimensional-impact-on-families-of-children-with-steroid-sensitive-nephrotic-syndrome
#18
Gurdeep S Dhooria, Harmeet P Singh, Deepak Bhat, Harmesh S Bains, Ravinder K Soni, Mohit Kumar
AIM: Children with nephrotic syndrome (NS) have prolonged disease course with relapses requiring frequent visits and prolonged steroid therapy with their long-term concerns. All these factors affect the child and their families in many domains of functioning. The objective of this study was to assess multidimensional impact on families of children with nephrotic syndrome using (PedsQL) Family Impact Module (FIM). METHODS: This cross-sectional study was conducted in a paediatric nephrology clinic of a tertiary care hospital...
January 6, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28054134/ultrasonographic-evidence-of-gatekeeper%C3%A2-prosthesis-migration-in-patients-treated-for-faecal-incontinence-a-case-series
#19
F de la Portilla, M L Reyes-Díaz, M V Maestre, R M Jiménez-Rodríguez, A M García-Cabrera, J M Vázquez-Monchul, J M Díaz-Pavón, F C Padillo-Ruiz
BACKGROUND: Faecal incontinence (FI) is both a medical and social problem, with an underestimated incidence. For patients with internal anal sphincter damage, implantation of biomaterial in the anal canal is a recognised treatment option. One such material, Gatekeeper™, has previously shown promising short- and medium-term results without any major complications, including displacement. The main aim of the present study is to assess the degree to which displacement of Gatekeeper prostheses may occur and to determine whether this is associated with patient outcomes...
January 4, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28053514/clinical-outcome-and-predictors-of-adverse-events-of-an-enhanced-older-adult-psychiatric-liaison-service-rapid-assessment-interface-and-discharge-newport
#20
Inderpal Singh, Priya Fernando, Jane Griffin, Chris Edwards, Kathryn Williamson, Patrick Chance
BACKGROUND: Hospitals are currently admitting an increasing number of older people, and more than one-third could have an underlying mental health problem. The existing Older Adult Mental Health (OAMH) liaison service was increasingly unable to meet the escalating needs of older and frail patients. Therefore, the service was modernized and enhanced on an "invest-to-save" principle to provide a prompt holistic assessment for older adults with mental health problems. The objective of this study was a service evaluation to appraise clinical outcome, minimize the length of stay, and measure the predictors of adverse outcomes to streamline this enhanced service...
2017: Clinical Interventions in Aging
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