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https://www.readbyqxmd.com/read/29331051/fecal-incontinence-knowledge-attitudes-and-help-seeking-behaviors-among-community-dwelling-adults-in-korea
#1
Hee-Kyung Joh, Moo-Kyung Seong, Hyun-Jun Ahn
OBJECTIVES: Fecal incontinence (FI) is a common debilitating disorder that tends to be underreported. Although low health literacy likely contributes to the underreporting, studies on FI knowledge among the general population remain scarce. We investigated how FI knowledge is associated with attitudes and help-seeking behaviors. METHODS: We conducted a cross-sectional survey among community-dwelling adults undergoing national health screening in Korea. A structured, self-administered questionnaire was used to assess FI knowledge, attitudes, and help-seeking behaviors...
January 13, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29328449/bioinformatics-analysis-to-screen-key-genes-implicated-in-the-differentiation-of-induced-pluripotent-stem-cells-to-hepatocytes
#2
Rui Lin, Yufeng Wang, Kun Ji, Zhongyan Liu, Shuai Xiao, Dehua Zhou, Quanning Chen, Baomin Shi
Due to the lack of potential organs, hepatocellular transplantation has been considered for treating end-stage liver disease. Induced pluripotent stem cells (iPSCs) are reverted from somatic cells and are able to differentiate into hepatocytes. The present study aimed to investigate the mechanisms underlying iPSC differentiation to hepatocytes. GSE66076 was downloaded from the Gene Expression Omnibus; this database includes data from 3 undifferentiated (T0), 3 definitive endoderm (T5), and 3 early hepatocyte (T24) samples across hepatic‑directed differentiation of iPSCs...
January 5, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29327443/effect-of-gut-stress-induced-by-oxidized-wheat-gluten-on-the-growth-performance-gut-morphology-and-oxidative-states-of-broilers
#3
R B Liao, H J Yan, G H Liu, S Zhang, W H Chang, W Liu, C H Lin, X Y Huang, H Y Cai
This study was to investigate the effect of oxidized wheat gluten (OG) on growth performance, gut morphology and its oxidative states of broilers. One hundred and eighty-day-old male broilers (10 chicks/pen) were randomly allocated into three dietary treatments: control diet (CON), diet with 8% wheat gluten (WG) and diet with 8% OG with six pens/treatment. Body weight (BW) (21 and 35 days) and average daily gain (ADG) (1-21 days and 22-35 days) decreased (p < .05) and feed conversion ratio (FCR) (1-21 days and 22-35 days) increased (p < ...
January 11, 2018: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29326379/blood-pressure-levels-post-mechanical-thrombectomy-and-outcomes-in-non-recanalized-large-vessel-occlusion-patients
#4
Nitin Goyal, Georgios Tsivgoulis, Abhi Pandhi, Kira Dillard, Diana Alsbrook, Jason J Chang, Balaji Krishnaiah, Christopher Nickele, Daniel Hoit, Khalid Alsherbini, Andrei V Alexandrov, Adam S Arthur, Lucas Elijovich
OBJECTIVE: Permissive hypertension may benefit patients with non-recanalized large vessel occlusion (nrLVO) post mechanical thrombectomy (MT) by maintaining brain perfusion. Data evaluating the impact of post-MT blood pressure (BP) levels on outcomes in nrLVO patients are scarce. We investigated the association of the post-MT BP course with safety and efficacy outcomes in nrLVO. METHODS: Hourly systolic BP (SBP) and diastolic BP (DBP) values were prospectively recorded for 24 hours following MT in consecutive nrLVO patients...
January 11, 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29325165/utilization-of-soy-hulls-oat-hulls-and-flax-meal-fiber-in-adult-broiler-breeder-hens
#5
H Leung, A Arrazola, S Torrey, E Kiarie
A total of 72, 65-week-old broiler breeder hens (Ross 308, BW 4,190 ± 45 g) was placed in individual cages to investigate utilization of fiber in soy hulls (SH), oat hulls (OH), and flax meal (FM). Birds were adapted to cages for 10 d prior to allocation (n = 18) to broiler breeder ration (control) or control mixed with either of the 3 fiber sources (wt/wt) added to supply equal amounts of neutral detergent fiber (NDF) ∼21% and TiO2. The daily feed allocation was based on 4% BW. Feed intake (FI) was monitored daily, and grab excreta samples were taken on d 16 and 17...
January 6, 2018: Poultry Science
https://www.readbyqxmd.com/read/29325158/influence-of-light-sources-and-photoperiod-on-growth-performance-carcass-characteristics-and-health-indices-of-broilers-grown-to-heavy-weights2
#6
H A Olanrewaju, W W Miller, W R Maslin, S D Collier, J L Purswell, S L Branton
Effects of light sources and photoperiod on growth performance, carcass characteristics and health indices of broilers were investigated in 4 trials. In each trial, 720 1-day-old Ross × Ross 708 chicks were randomly distributed into 12 environmentally controlled rooms (30 males/30 females/room). The experimental design was a 4 × 3 factorial treatments consisted of 4 light sources [incandescent (ICD, standard), compact fluorescent (CFL), neutral light-emitting diode (Neutral-LED), and cool poultry-specific filtered LED (Cool-PSF-LED)] and 3 photoperiods [long/continuous (23L:1D), regular/intermittent (2L:2D), and short/non-intermittent (8L:16D)] from d8-d56...
January 6, 2018: Poultry Science
https://www.readbyqxmd.com/read/29324429/a-pilot-clinical-study-of-a-safe-and-efficient-stool-management-system-in-patients-with-fecal-incontinence
#7
Ashlee Garcia, Sally Fung, Karen Lou Kennedy-Evans
INTRODUCTION: According to the Wound Ostomy Continence Nursing Society's Continence Committee, the incidence of fecal incontinence (FI) can occur from 18% to 37% in an acute care setting. A stool management system has been designed to manage FI in bedridden patients and has proven to be efficacious in wound management and prevention and infection control, provide safer patient outcomes, and enhance ease of nursing. OBJECTIVE: This study aims to evaluate the safety and efficacy of an intrarectal device intended to manage fecal incontinence in hospitalized bedridden patients through nonclinical and clinical testings...
December 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/29315267/experimental-evaluation-of-uwb-indoor-positioning-for-sport-postures
#8
Matteo Ridolfi, Stef Vandermeeren, Jense Defraye, Heidi Steendam, Joeri Gerlo, Dirk De Clercq, Jeroen Hoebeke, Eli De Poorter
Radio frequency (RF)-based indoor positioning systems (IPSs) use wireless technologies (including Wi-Fi, Zigbee, Bluetooth, and ultra-wide band (UWB)) to estimate the location of persons in areas where no Global Positioning System (GPS) reception is available, for example in indoor stadiums or sports halls. Of the above-mentioned forms of radio frequency (RF) technology, UWB is considered one of the most accurate approaches because it can provide positioning estimates with centimeter-level accuracy. However, it is not yet known whether UWB can also offer such accurate position estimates during strenuous dynamic activities in which moves are characterized by fast changes in direction and velocity...
January 9, 2018: Sensors
https://www.readbyqxmd.com/read/29314613/validation-and-comparison-of-seventeen-noninvasive-models-for-evaluating-liver-fibrosis-in-chinese-hepatitis-b-patients
#9
Minhui Dong, Jingwen Wu, Xueping Yu, Jing Li, Sisi Yang, Xun Qi, Richeng Mao, Yongmei Zhang, Jie Yu, Haoxiang Zhu, Feifei Yang, Yanli Qin, Jiming Zhang
BACKGROUND & AIMS: To avoid liver biopsy, many noninvasive models comprised of serum markers for liver fibrosis assessment have been developed. Given that most of them were developed in hepatitis C cohorts and few of them have been validated in Chinese hepatitis B patients, we aim to conduct this validation and compare their diagnostic accuracies in such a population. METHODS: A total of 937 HBV infected patients who underwent liver biopsy were included in this single-center retrospective study...
January 3, 2018: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29313165/effectiveness-of-sacral-nerve-stimulation-in-fecal-incontinence-after-multimodal-oncologic-treatment-for-pelvic-malignancies-a-multicenter-study-with-2-year-follow-up
#10
M Schiano di Visconte, G A Santoro, N Cracco, G Sarzo, G Bellio, M Brunner, Z Cui, K E Matzel
BACKGROUND: To assess whether sacral nerve stimulation (SNS) is an effective treatment for severe fecal incontinence (FI) after radiotherapy (RT)/chemoRT (CRT) in combination with pelvic surgery. METHODS: A multicenter study was conducted on patients with FI that developed after multimodal therapy for pelvic tumors and was refractory to non-operative management, who were treated with SNS between November 2009 and November 2012. Data were prospectively collected and retrospectively analyzed...
January 8, 2018: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29311616/yield-and-resource-use-efficiency-of-plukenetia-volubilis-plants-at-two-distinct-growth-stages-as-affected-by-irrigation-and-fertilization
#11
He-De Gong, Yan-Jing Geng, Chun Yang, Dong-Ying Jiao, Liang Chen, Zhi-Quan Cai
This study is to test how seedlings (vegetative) and large plants (reproductive) of an oilseed crop (Plukenetia volubilis) responded to regulated deficit irrigation techniques (conventional deficit irrigation, DI; alternative partial root-zone irrigation, APRI) in a tropical humid monsoon area. Seedlings were more sensitive to water deficit than large plants. Although APRI did better than DI in saving water for both seedlings and large plants at the same amount of irrigation, full irrigation (FI) is optimal for faster seedling growth at the expense of water-use efficiency (WUE)...
January 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29303061/indocyanine-green-fluorescence-imaging-guided-surgery-in-primary-and-metastatic-liver-tumors
#12
Eva Lieto, Gennaro Galizia, Francesca Cardella, Andrea Mabilia, Nicoletta Basile, Paolo Castellano, Michele Orditura, Annamaria Auricchio
BACKGROUND: After surgery for liver tumors, recurrence rates remain high because of residual positive margins or undiagnosed lesions. It has been suggested that detection of hepatic tumors can be obtained with near-infrared fluorescence imaging (FI). Indocyanine green (ICG) has been used with contrasting results. The aims of this study were to explore ICG-FI-guided surgery methodology and to assess its potential applications. MATERIALS AND METHODS: Out of 14 patients with liver tumors, 5 were not operated on, and 9 patients (3 primary and 6 metastatic tumors) underwent surgery...
January 1, 2018: Surgical Innovation
https://www.readbyqxmd.com/read/29299219/comparison-of-elbow-flexor-isokinetic-peak-torque-and-fatigue-index-between-men-and-women-of-different-training-level
#13
Paulo Gentil, Mario Hebling Campos, Saulo Soares, Gustavo De Conti Teixeira Costa, Antonio Paoli, Antonino Bianco, Martim Bottaro
The purpose of the study was to compare elbow flexion peak torque (PT) and fatigue index (FI) during isokinetic concentric contractions in men and women with different training levels. Sixty-eight young men and women were divided into four groups: resistance trained men (RTM), non-resistance trained men (NRTM), resistance trained women (RTW) and non- resistance trained women (NRTW). Participants performed two tests on an isokinetic dynamometer, one to evaluate PT and one to evaluate FI. Significant interactions were found for sex and resistance training status with both PT and FI...
December 5, 2017: European Journal of Translational Myology
https://www.readbyqxmd.com/read/29291073/lattice-geometry-effects-in-garnet-solid-electrolytes-a-lattice-gas-monte-carlo-simulation-study
#14
Benjamin J Morgan
Ionic transport in solid electrolytes can often be approximated as ions performing a sequence of hops between distinct lattice sites. If these hops are uncorrelated, quantitative relationships can be derived that connect microscopic hopping rates to macroscopic transport coefficients; i.e. tracer diffusion coefficients and ionic conductivities. In real materials, hops are uncorrelated only in the dilute limit. At non-dilute concentrations, the relationships between hopping frequency, diffusion coefficient and ionic conductivity deviate from the random walk case, with this deviation quantified by single-particle and collective correlation factors, f and fI, respectively...
November 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/29290809/near-infrared-intraoperative-imaging-of-thoracic-sympathetic-nerves-from-preclinical-study-to-clinical-trial
#15
Kunshan He, Jian Zhou, Fan Yang, Chongwei Chi, Hao Li, Yamin Mao, Bengang Hui, Kun Wang, Jie Tian, Jun Wang
The sympathetic nervous system controls and regulates the activities of the heart and other organs. Sympathetic nervous system dysfunction leads to disease. Therefore, intraoperative real-time imaging of thoracic sympathetic nerves (ITSN) would be of great clinical significance for diagnosis and therapy. The aim of this experimental study was to evaluate the feasibility and validity of intraoperative ITSN using indocyanine green (ICG). METHODS: ITSN using ICG was performed on 10 rabbits to determine its feasibility...
2018: Theranostics
https://www.readbyqxmd.com/read/29285556/mixotrophic-cultivation-of-microalgae-to-enhance-the-quality-of-lipid-for-biodiesel-application-effects-of-scale-of-cultivation-and-light-spectrum-on-reduction-of-%C3%AE-linolenic-acid
#16
Suvidha Gupta, Sanjay B Pawar
The research on microalgal biodiesel is focused not only on getting the highest lipid productivity but also desired quality of lipid. The experiments were initially conducted on flask scale (1L) using acetate carbon source at different concentrations viz. 0.5, 2, 3 and 4 g L-1. The optimum concentration of acetate was considered for further experiments in two airlift photobioreactors (10 L) equipped separately with red and white LED lights. The Feasibility Index (FI) was derived to analyze the scalability of mixotrophic cultivation based on net carbon fixation in biomass per consumption of total organic carbon...
December 29, 2017: Bioprocess and Biosystems Engineering
https://www.readbyqxmd.com/read/29281621/the-translesion-dna-polymerases-pol-%C3%AE-and-rev1-are-activated-independently-of-pcna-ubiquitination-upon-uv-radiation-in-mutants-of-dna-polymerase-%C3%AE
#17
Carine Tellier-Lebegue, Eléa Dizet, Emilie Ma, Xavier Veaute, Eric Coïc, Jean-Baptiste Charbonnier, Laurent Maloisel
Replicative DNA polymerases cannot insert efficiently nucleotides at sites of base lesions. This function is taken over by specialized translesion DNA synthesis (TLS) polymerases to allow DNA replication completion in the presence of DNA damage. In eukaryotes, Rad6- and Rad18-mediated PCNA ubiquitination at lysine 164 promotes recruitment of TLS polymerases, allowing cells to efficiently cope with DNA damage. However, several studies showed that TLS polymerases can be recruited also in the absence of PCNA ubiquitination...
December 27, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/29273703/frailty-index-as-a-predictor-of-all-cause-and-cause-specific-mortality-in-a-swedish-population-based-cohort
#18
Miao Jiang, Andrea Dawn Foebel, Ralf Kuja-Halkola, Ida Karlsson, Nancy Lee Pedersen, Sara Hägg, Juulia Jylhävä
Frailty is a complex manifestation of aging and associated with increased risk of mortality and poor health outcomes. However, younger individuals (under 65 years) are less-studied in this respect. Also, the relationship between frailty and cause-specific mortality in community settings is understudied. We used a 42-item Rockwood-based frailty index (FI) in the Swedish Adoption/Twin Study of Aging (n=1477; 623 men, 854 women; aged 29-95 years) and analyzed its association with all-cause and cause-specific mortality in up to 30-years of follow-up...
December 19, 2017: Aging
https://www.readbyqxmd.com/read/29259006/consensusdriver-improves-upon-individual-algorithms-for-predicting-driver-alterations-in-different-cancer-types-and-individual-patients
#19
Denis Bertrand, Sibyl Drissler, Burton K Chia, Jia Yu Koh, Chenhao Li, Chayaporn Suphavilai, Iain Beehuat Tan, Niranjan Nagarajan
Existing cancer driver prediction methods are based on very different assumptions and each of them can detect only a particular subset of driver genes. Here we perform a comprehensive assessment of 18 driver prediction methods on more than 3,400 tumor samples from 15 cancer types, all to determine their suitability in guiding precision medicine efforts. We categorized these methods into five groups: functional impact on proteins in general (FI) or specific to cancer (FIC), cohort-based analysis for recurrent mutations (CBA), mutations with expression correlation (MEC), and methods that use gene interaction network-based analysis (INA)...
December 19, 2017: Cancer Research
https://www.readbyqxmd.com/read/29258831/identification-and-characterization-of-proteins-in-the-amblyomma-americanum-tick-cement-cone
#20
Taylor Hollmann, Tae Kwon Kim, Lucas Tirloni, Željko M Radulović, Antônio F M Pinto, Jolene K Diedrich, John R Yates, Itabajara da Silva Vaz, Albert Mulenga
The adaptation of hard ticks to feed for long periods is facilitated by the cement cone, which securely anchors the tick mouthparts onto host skin and protects the tick from being groomed off by the host. Thus, preventing tick cement deposition is an attractive target for the development of innovative tick control. We used LC-MS/MS sequencing to identify 160 Amblyomma americanum tick cement proteins that include glycine-rich proteins (GRP, 19%), protease inhibitors (12%), proteins of unknown function (11%), mucin (4%), detoxification, storage, and lipocalin at 1% each, and housekeeping proteins (50%)...
December 16, 2017: International Journal for Parasitology
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