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https://www.readbyqxmd.com/read/27914018/encapsulation-of-%C3%AE-sitosterol-in-polyurethane-by-sol-gel-electrospinning
#1
Musarat Amina, Touseef Amna, Nawal Al-Musayeib, Sami A Zabin, M Shamshi Hassan, Myung-Seob Khil
Pristine β-sitosterol or in combination with other phytosterols is utilized in an array of enriched commercial foods. Considering the presence of β-sitosterol in different functional foods and its potential role in prevention and cure of neurodegenerative diseases, the aims of our investigation were to encapsulate β-sitosterol in nanofibers and to estimate influence of β-sitosterol on proliferation of fibroblasts. Electrospun nanofibers have widely been used as scaffolds to mimic natural extracellular matrix...
December 2, 2016: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/27913209/abl2-kinase-phosphorylates-bi-organellar-regulator-mnrr1-in-mitochondria-stimulating-respiration
#2
Siddhesh Aras, Hassan Arrabi, Neeraja Purandare, Maik Hüttemann, John Kamholz, Stephan Züchner, Lawrence I Grossman
We previously showed that MNRR1 (Mitochondrial Nuclear Retrograde Regulator 1, also CHCHD2) functions in two subcellular compartments, displaying a different function in each. In the mitochondria it is a stress regulator of respiration that binds to cytochrome c oxidase (COX) whereas in the nucleus it is a transactivator of COX4I2 and other hypoxia-stimulated genes. We now show that binding of MNRR1 to COX is promoted by phosphorylation at tyrosine-99 and that this interaction stimulates respiration. We show that phosphorylation of MNRR1 takes place in mitochondria and is mediated by Abl2 kinase (ARG)...
November 29, 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27912236/prognostic-role-of-pten-gene-expression-in-breast-cancer-patients-from-north-east-iran
#3
Rahim Golmohammadi, Mohammad Hassan Rakhshani, Ali Reza Moslem, Akbar Pejhan
Background: PTEN protein is one of the most important tumour suppressor factors which is detectable by immunohistochemistry. The goal of the present study was to investigate the prognostic role of PTEN gene expression in breast cancer patients. Materials and Methods: This descriptive-analytical study was conducted on 100 breast cancer patients referred to Sabzevar hospitals in the north-east of Iran between 2010 and 2011, who were followed up to 2015. PTEN gene expression in tissue samples was determined using specific monoclonal antibodies and data were analyzed using Chi-square test and Fisher’s exact test...
January 9, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27912188/bacillus-flexus-strain-as-12-a-new-arsenic-transformer-bacterium-isolated-from-contaminated-water-resources
#4
Mohammad Ahmadi Jebeli, Afshin Maleki, Mohammad Ali Amoozegar, Enayatollah Kalantar, Hassan Izanloo, Fardin Gharibi
A total of 14 arsenic-resistant bacteria were isolated from an arsenic-contaminated travertine spring water in the central district of Qorveh county, Kurdistan Province, Iran. One of strains designated As-12 was selected for further investigation because of its ability to transform arsenic. The strain was identified by cultural, morphological and biochemical tests, and 16S rRNA gene sequencing. Finally, the growth characteristics of the isolate were investigated in a chemically defined medium which included varied ranges of environmental factors such as pH, temperature and salinity...
November 29, 2016: Chemosphere
https://www.readbyqxmd.com/read/27911488/hepatocellular-carcinoma-as-an-emerging-morbidity-in-the-thalassemia-syndromes-a-comprehensive-review
#5
REVIEW
Hassan M Moukhadder, Racha Halawi, Maria Domenica Cappellini, Ali T Taher
The incidence of hepatocellular carcinoma (HCC) in patients with thalassemia is on the rise. The 2 well recognized HCC risk factors in thalassemia are iron overload and chronic viral infection with hepatitis C. The carcinogenicity of iron is related to its induction of oxidative damage, which results in genotoxicity, and to immunologic dysregulation, which attenuates cancer immune surveillance. Chronic hepatitis B and C infections lead to necroinflammation, which can prompt progression to HCC, but an independent role of hepatitis B virus in hepatic carcinogenesis among patients with thalassemia has not been demonstrated...
December 1, 2016: Cancer
https://www.readbyqxmd.com/read/27911463/vascular-access-types-in-patients-starting-hemodialysis-after-failed-kidney-transplant-does-close-nephrology-follow-up-matter
#6
Naveed Ul Haq, Mohamed Said Abdelsalam, Mohammed Mahdi Althaf, Abdulrahman Ali Khormi, Hassan Al Harbi, Bader Alshamsan, Mamdouh Nasser Albaqumi, Dieter Clemens Broering, Lutfi Alkorbi, Hassan Ali Aleid
BACKGROUND: Native arteriovenous fistulae (AVFs) are preferred while central venous catheters (CVCs) are least suitable vascular access (VA) in patients requiring hemodialysis (HD). Unfortunately, around 80% of patients start HD with CVCs. Late referral to nephrologist is thought to be a factor responsible for this. We retrospectively analyzed the types of VA at HD initiation in renal transplant recipients followed by nephrologists with failed transplant. If early referral to nephrologist improves AVF use, these patients should have higher prevalence of AVF at HD initiation...
November 28, 2016: Journal of Vascular Access
https://www.readbyqxmd.com/read/27911220/optimization-of-a-textile-dye-degradation-in-a-recirculating-fluidized-bed-reactor-using-magnetite-s2o8-2-process
#7
Hassan Aghdasinia, Parvin Arehjani, Behrouz Vahid, Alireza Khataee
Optimization of Acid Orange 7 (AO7) treatment using heterogeneous Fenton-like method in a recirculating fluidized-bed reactor (FBR) was investigated by central composite design (CCD). Natural magnetite (NM) as Fenton-like catalyst was characterized using scanning electron microscopy (SEM). Nonlinear CCD model was obtained for prediction of dye degradation as a function of experimental variables such as peroxydisulfate concentration (0.1-0.5 mmol/L), initial AO7 concentration (5-25 mg/L), pH (3-9) and NM dosage (0...
December 2, 2016: Environmental Technology
https://www.readbyqxmd.com/read/27910760/immunomodulation-effect-of-aqueous-extract-of-the-artist-s-conk-medicinal-mushroom-ganoderma-applanatum-agaricomycetes-on-the-rainbow-trout-oncorhynchus-mykiss
#8
Azadeh Manayi, Mahdi Vazirian, Fereshteh Hassan Zade, Akram Tehranifard
It is well known that innate immunity in fish can be activated by many synthetic and natural immunos-timulants; several natural substances induced immunity in fish in previous surveys. This study discussed data regarding the effect of Ganoderma applanatum aqueous extract on the defense mechanisms of rainbow trout in feeding trials. Fish were fed 250, 500, and 1000 mg extract/kg diet 4 times daily. Growth, humoral parameters, lysozyme activity, and serum protein concentrations were assessed after a period of 45 days...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/27910675/erratum-a-fast-real-time-measurement-system-to-track-in-and-out-of-plane-optical-retardation-birefringence-true-stress-and-true-strain-during-biaxial-stretching-of-polymer-films-rev-sci-instrum-83-123901-2012
#9
https://www.readbyqxmd.com/read/27909883/high-expression-of-ceacam19-a-new-member-of-carcinoembryonic-antigen-gene-family-in-patients-with-breast-cancer
#10
Mehrdad Asghari Estiar, Rezvan Esmaeili, Ali-Akbar Zare, Leila Farahmand, Hassan Fazilaty, Ali Zekri, Narges Jafarbeik-Iravani, Keivan Majidzadeh-A
Carcinoembryonic antigen (CEA) family members play important roles in malignancies and are introduced as biomarkers in different types of cancers. Among them CEACAM19 (CEAL1) gene, a new member of the CEA family, remains to be fully elucidated. The aim of this study was investigating the mRNA expression level of CEACAM19 in tumor samples of breast cancer patients compared to breast tissue of normal individuals. We evaluated the expression level of this gene in 75 breast tumors by using real-time quantitative PCR...
December 1, 2016: Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/27909547/gastrointestinal-tract-access-for-urological-natural-orifice-transluminal-endoscopic-surgery
#11
REVIEW
Olga Miakicheva, Zachary Hamilton, Alp T Beksac, Sean W Berquist, Abd-Elrahman Hassan, Marc Holden, Ithaar H Derweesh
We conducted a literature review of natural orifice transluminal endoscopic surgery (NOTES), focusing on urologic procedures with gastrointestinal tract access, to update on the development of this novel surgical approach. As part of the methods, a comprehensive electronic literature search for NOTES was conducted using PubMed and Cochrane Library from March 2002 to February 2016 for papers reporting urologic procedures performed utilizing gastrointestinal tract access. A total of 11 peer-reviewed studies examining utility of gastrointestinal access for NOTES urologic procedures were noted, with the first report in 2007...
November 16, 2016: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27909048/the-ph-dependence-of-saccharides-influence-on-thermal-denaturation-of-two-model-proteins-supports-an-excluded-volume-model-for-stabilization-generalized-to-allow-for-intramolecular-electrostatic-interactions
#12
Ilyas Beg, Allen P Minton, Asimul Islam, Md Imtaiyaz Hassan, Faizan Ahmad
The reversible thermal denaturation of apo alpha-lactalbumin and lysozyme was measured in the absence and presence of multiple concentrations of each of seven saccharides (glucose, galactose, fructose, sucrose, trehalose, raffinose and stachyose) at multiple pH values. It was observed that with increasing pH, the absolute stability of alpha-lactalbumin decreased while the stabilizing effect per mole of all saccharides increased, and that the absolute stability of lysozyme increased, while the stabilizing effect per mole of all saccharides decreased...
December 1, 2016: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/27908539/design-synthesis-molecular-docking-anti-proteus-mirabilis-and-urease-inhibition-of-new-fluoroquinolone-carboxylic-acid-derivatives
#13
Mohammed A A Abdullah, Gamal El-Din A A Abuo-Rahma, El-Shimaa M N Abdelhafez, Heba A Hassan, Rehab M Abd El-Baky
New hydroxamic acid, hydrazide and amide derivatives of ciprofloxacin in addition to their analogues of levofloxacin were prepared and identified by different spectroscopic techniques. Some of the prepared compounds revealed good activity against the urease splitting bacteria, Proteus mirabilis. The urease inhibitory activity was investigated using indophenol method. Most of the tested compounds showed better activity than the reference acetohydroxamic acid (AHA). The ciprofloxacin hydrazide derivative 3a and levofloxacin hydroxamic acid 7 experienced the highest activity (IC50=1...
November 9, 2016: Bioorganic Chemistry
https://www.readbyqxmd.com/read/27906961/tracking-insecticide-resistance-in-mosquito-vectors-of-arboviruses-the-worldwide-insecticide-resistance-network-win
#14
Vincent Corbel, Nicole L Achee, Fabrice Chandre, Mamadou B Coulibaly, Isabelle Dusfour, Dina M Fonseca, John Grieco, Waraporn Juntarajumnong, Audrey Lenhart, Ademir J Martins, Catherine Moyes, Lee Ching Ng, João Pinto, Kamaraju Raghavendra, Hassan Vatandoost, John Vontas, David Weetman, Florence Fouque, Raman Velayudhan, Jean-Philippe David
No abstract text is available yet for this article.
December 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27906936/analgesic-effect-of-nalbuphine-when-added-to-intravenous-regional-anesthesia-a-randomized-control-trial
#15
Mohamed Hassan Bakri, Eman Ahmed Ismail, Sayed Kaoud Abd-Elshafy
BACKGROUND: Different adjuvant drugs are currently added to lidocaine for intravenous regional anesthesia (IVRA) to decrease tourniquet and postoperative pain. OBJECTIVE: The aim of the study was to examine the effect of nalbuphine when added toIVRA. STUDY DESIGN: Prospective, randomized, double-blind, controlled clinical trial. SETTING: Assiut University Hospitals. METHODS: One hundred-six adult patients scheduled for unilateral hand surgery under IVRA were randomized into 2 equal groups...
November 2016: Pain Physician
https://www.readbyqxmd.com/read/27905932/adaptation-and-validation-of-the-instrument-clinical-learning-environment-and-supervision-for-medical-students-in-primary-health-care
#16
Eva Öhman, Hassan Alinaghizadeh, Päivi Kaila, Håkan Hult, Gunnar H Nilsson, Helena Salminen
BACKGROUND: Clinical learning takes place in complex socio-cultural environments that are workplaces for the staff and learning places for the students. In the clinical context, the students learn by active participation and in interaction with the rest of the community at the workplace. Clinical learning occurs outside the university, therefore is it important for both the university and the student that the student is given opportunities to evaluate the clinical placements with an instrument that allows evaluation from many perspectives...
December 1, 2016: BMC Medical Education
https://www.readbyqxmd.com/read/27904870/preclinical-study-of-68-ga-dotatoc-biodistribution-assessment-in-syrian-rats-and-evaluation-of-absorbed-dose-in-human-organs
#17
Mojdeh Naderi, Samaneh Zolghadri, Hassan Yousefnia, Ali Ramazani, Amir Reza Jalilian
OBJECTIVES: Gallium-68 DOTA-DPhe(1)-Tyr(3)-Octreotide ((68)Ga-DOTATOC) has been applied by several European centers for the treatment of a variety of human malignancies. Nevertheless, definitive dosimetric data are yet unavailable. According to the Society of Nuclear Medicine and Molecular Imaging, researchers are investigating the safety and efficacy of this radiotracer to meet Food and Drug Administration requirements. The aim of this study was to introduce the optimized procedure for (68)Ga-DOTATOC preparation, using a novel germanium-68 ((68)Ge)/(68)Ga generator in Iran and evaluate the absorbed doses in numerous organs with high accuracy...
2016: Asia Oceania Journal of Nuclear Medicine & Biology
https://www.readbyqxmd.com/read/27904615/the-effect-of-flaxseed-powder-on-insulin-resistance-indices-and-blood-pressure-in-prediabetic-individuals-a-randomized-controlled-clinical-trial
#18
Afrooz Javidi, Hassan Mozaffari-Khosravi, Azadeh Nadjarzadeh, Ali Dehghani, Mohammad Hassan Eftekhari
BACKGROUND: Designing the effective and early interventions can prevent progression of prediabetes to diabetes. Few studies have shown the effect of flaxseed on glycemic control. This study aimed to assess the effect of flaxseed powder on insulin resistance (IR) indices and blood pressure in prediabetic individuals. MATERIALS AND METHODS: In a randomized clinical trial, 99 prediabetic individuals were randomly divided into three groups: two groups received 40 g (FG40) and 20 g (FG20) flaxseed powder daily for 12 weeks and the third group was the control (CG)...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27904611/selective-serotonin-reuptake-inhibitors-and-cardiovascular-events-a-systematic-review
#19
REVIEW
Mohammad Hassan Nezafati, Ali Eshraghi, Mohammad Vojdanparast, Saeed Abtahi, Pouya Nezafati
BACKGROUND: Given the importance of the role of depression in predicting the outcome of cardiovascular disorders, current medications for treating depression, particularly selective serotonin reuptake inhibitors (SSRIs), are taken into consideration. This study aimed to systematically review the published findings in the use of SSRIs and the risk for cardiac events. MATERIALS AND METHODS: An independent review of the Web of Science, PubMed, Scopus, Cochrane, CINAHL, index Copernicus, and Google Scholar, up to 2014, was performed...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27904589/pseudo-subarachnoid-hemorrhage-and-optic-neuritis-in-an-18-year-old-girl-with-sodium-valproate-overdose
#20
Bita Dadpour, Hassan Abbaspour, Ali Pourzahed, Ahmad Bagheri Moghadam
No abstract text is available yet for this article.
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
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