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Facial filler

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https://www.readbyqxmd.com/read/28731160/adipose%C3%A2-derived-stem-cells-and-hyaluronic-acid-based-gel-compatibility-studied-in-vitro
#1
Jiayan Guo, Shu Guo, Yuxin Wang, Yanqiu Yu
Minimally invasive aesthetic and cosmetic procedures have increased in popularity. Injectable dermal fillers provide soft tissue augmentation, improve facial rejuvenation and wrinkles, and correct tissue defects. To investigate the use of adipose‑derived stem cells integrated with a hyaluronic acid based gel as a dermal filler, the present study used cytotoxicity studies, proliferation studies, adipogenic and osteogenic differentiation, apoptosis assays and scanning electron microscopy. Although hyaluronic acid induced low levels of apoptosis in adipose‑derived stem cells, its significantly promoted proliferation of adipose‑derived stem cells...
July 21, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28728332/skin-necrosis-with-oculomotor-nerve-palsy-due-to-a-hyaluronic-acid-filler-injection
#2
Jae Il Lee, Seok Joo Kang, Hook Sun
Performing rhinoplasty using filler injections, which improve facial wrinkles or soft tissues, is relatively inexpensive. However, intravascular filler injections can cause severe complications, such as skin necrosis and visual loss. We describe a case of blepharoptosis and skin necrosis caused by augmentation rhinoplasty and we discuss the patient's clinical progress. We describe the case of a 25-year-old female patient who experienced severe pain, blepharoptosis, and decreased visual acuity immediately after receiving a filler injection...
July 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/28715577/device-safety-implications-of-the-clinical-data-leading-to-us-food-and-drug-administration-approval-of-soft-tissue-fillers-a-systematic-review
#3
Mary E Lohman, Comeron W Ghobadi, Shuai Xu
Importance: The US Food and Drug Administration (FDA) recently issued a safety warning regarding soft-tissue fillers (STFs) based on the risk of blindness and facial necrosis. Objective: To examine the quality of evidence leading to FDA approval of STFs. Evidence Review: All original approvals for STFs were mined using the publicly available FDA database. The Cochrane Collaboration's risk of bias assessment tool was applied to all randomized clinical trials (RCTs)...
July 13, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28702968/in-vitro-evaluation-of-collagen-production-on-human-fibroblasts-treated-with-hyaluronic-acid-peg-cross-linked-with-micromolecules-of-calcium-hydroxyapatite-in-low-concentration
#4
N Zerbinati, R Rauso, P Gonzalez, M Cherubino, E D'Este, A Calligaro, S Sommatis, C Maccario, R Mocchi
Neauvia Stimulate® is a biocompatible, injectable hyaluronic acid (HA) filler (26 mg/ml) PEG cross-linked with 1% of calcium hydroxyapatite (CaHA) for facial soft-tissue augmentation that provides volume to tissues, followed by a process of neocollagenesis for improving skin quality. The aim of the present study is to evaluate the possible modulation of collagen synthesis after treating human fibroblasts cultured in vitro with the product (Lot. 160517-26-1/2 PEG). The experimental model proposed, despite being an in vitro system, allows the derivation of useful information to predict the possible activity of the product in further in vivo application...
July 13, 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28702187/procedure-applications-and-outcomes-of-autologous-fat-grafting
#5
REVIEW
Francesco Simonacci, Nicolò Bertozzi, Michele Pio Grieco, Eugenio Grignaffini, Edoardo Raposio
OBJECTIVE: To systematically review the procedure, applications, and outcomes of autologous fat grafting, a promising technique with various clinical applications. PATIENTS AND METHODS: Literature review of publications concerning autologous fat grafting. RESULTS: Since its introduction, lipofilling has become increasingly popular; however, its results are variable and unpredictable. Several modifications have been made to the procedures of fat harvesting, processing, and injecting...
August 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28652795/minimal-recovery-time-needed-to-return-to-social-engagement-following-nasolabial-fold-correction-with-hyaluronic-acid-fillers-produced-with-xpreshan-technology
#6
Arthur Swift, Erika von Grote, Brandie Jonas, Alessandra Nogueira
INTRODUCTION: The appeal of hyaluronic acid fillers for facial soft tissue augmentation is attributable to both an immediate aesthetic effect and relatively short recovery time. Although recovery time is an important posttreatment variable, as it impacts comfort with appearance and perceived treatment benefit, it is not routinely evaluated. Natural-looking aesthetic outcomes are also a primary concern for many patients. MATERIALS AND METHODS: A single-center, noncomparative study evaluated the time (in hours) until subjects return to social engagement (RtSE) following correction of moderate and severe nasolabial folds (NLFs) with RR (Restylane(®) Refyne)(®) and RD (Restylane Defyne), respectively...
2017: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/28645662/development-of-a-3d-printable-maxillofacial-silicone-part-ii-optimization-of-moderator-and-thixotropic-agent
#7
Swati K Jindal, Martyn Sherriff, Mark G Waters, James E Smay, Trevor J Coward
STATEMENT OF PROBLEM: Conventionally, maxillofacial prostheses are fabricated by hand carving the missing anatomic defect in wax and creating a mold into which pigmented silicone elastomer is placed. Digital technologies such as computer numerical control milling and 3-dimensional (3D) printing have been used to prepare molds, directly or indirectly, into which a biocompatible pigmented silicone elastomer can be placed. PURPOSE: The purpose of this in vitro study was to develop a silicone elastomer that could be 3D printed directly without a mold to create facial or body prostheses by varying its composition...
June 20, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28643010/discussion-nonsurgical-facial-rejuvenation-outcomes-and-safety-of-neuromodulator-and-soft-tissue-filler-procedures-performed-in-a-resident-cosmetic-clinic
#8
Devra B Becker
No abstract text is available yet for this article.
June 22, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28643008/correction-of-rhytides-peau-d-orange-and-thin-dermis-of-the-face-by-neocollagenesis-using-novel-collagen-stimulating-slurry-protocol
#9
Steven Dominguez, Marek Dobke
We reviewed 200 patient records from 2009 to 2015 of individuals who presented at the authors offices for facial wrinkle reduction and who on physical examination had rhytides, peau d'orange, or thin dermis and underwent novel adipose slurry injections. The patients were evaluated at week 2, 1, 3 and 6 months revealing an 80, 60 and 40% improvement in rhytides and dermis density, respectively. We present the protocol and description of a reasonable alternative or adjunct to manufactured fillers that is comprised of autologous adipose, stem cells, and growth factor slurry...
June 22, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28639068/what-about-the-rheological-properties-of%C3%A2-prp-microfat-mixtures-in-fat-grafting-procedure
#10
R Ghazouane, B Bertrand, C Philandrianos, J Veran, M Abellan, P Francois, M Velier, C Orneto, P Piccerelle, J Magalon
BACKGROUND: Fat grafting has emerged as a reference procedure in daily plastic surgery practice. Unpredictable fat resorption is the main clinical problem. For this purpose, the addition of PRP to enhance fat revascularization is now an easy and popular procedure. However, no consensus exists regarding the respective volume of fat and PRP used to obtain the ideal mixture. This study investigated the rheological properties of microfat mixed with different proportions of PRP. Results obtained were compared with commercialized hyaluronic acid fillers...
June 21, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28632885/restoring-facial-symmetry-through-non-surgical-cosmetic-procedures-after-permanent-facial-paralysis-a-case-report
#11
Ali Sahan, Funda Tamer
Facial nerve paralysis can occur due to infection, inflammation, trauma, surgery, and tumors. It leads to facial asymmetry, impaired oral competence, articulation deficits, and psychological problems. Treatment options include physical therapy, static slings, nerve and muscle transfers, blepharoplasty, brow lift, and chemodenervation with botulinum toxin. We report the case of a 66-year-old Caucasian female with permanent facial paralysis following middle ear surgery. The facial asymmetry was treated successfully with botulinum toxin A injection, hyaluronic acid dermal filler injection, and a thread-lift procedure...
June 2017: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
https://www.readbyqxmd.com/read/28628686/off-face-usage-of-poly-l-lactic-acid-for-body-rejuvenation
#12
Ahmad Jabbar, Suleima Arruda, Neil Sadick
<p>Injectable soft-tissue augmentation agents have become popular alternatives to surgical procedures for the aging face and body. In contrast to temporary, space-occupying replacement fillers such as collagen-based and hyaluronic acid products, poly-l-lactic acid (PLLA) has been demonstrated to gradually promotes deposition of collagen via a biostimulatory response, with therapeutic effects lasting approximately two years. In 2004, the FDA approved its use for rejuvenation of facial contours secondary to lipoatrophy associated with antiretroviral therapy for HIV infection...
May 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28574197/cross-sectional-study-of-the-microbiological-safety-profile-of-reusing-hyaluronic-acid-fillers
#13
Rubens Pontello, Rogério Nabor Kondo, Priscila Daiane Pavezzi, Theo Nicolacopulos, Julia Pagung Kippert, Clarissa Lena
INTRODUCTION: Facial filling with hyaluronic acid (HA) is a dermatological procedure that has been emerging today. There are not many references regarding safety of reusing the remaining product for later touch-up in the same patient. OBJECTIVE: To determine the microbiological safety of reusing hyaluronic acid that is remnant from syringes used for facial filling, stored at room temperature or cooled in a refrigerator at 4°C. MATERIALS AND METHODS: In culture medium, small aliquots of leftovers from 31 hyaluronic acid fillers, previously used for facial filling, were inoculated...
June 2, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28571065/cheek-and-chin-implants-to-enhance-facelift-results
#14
Russell W H Kridel, Sagar Patel
The traditional rhytidectomy addresses facial and neck aging as it relates to soft tissue laxity. The modern volumetric facelift provides optimal results by addressing not only skin laxity but also the loss of volume secondary to tissue atrophy and bony resorption. While multiple techniques including fat grafting, dermal fillers, and tissue resuspension are used to correct the tissue loss, alloplastic midface augmentation remains the most permanent method. In our practice we often address midface cheek hollowness or atrophy with the placement of submalar implants at the time of rhytidectomy...
June 2017: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/28567474/impending-facial-skin-necrosis-and-ocular-involvement-after-dermal-filler-injection-a-case-report
#15
André Salval, Francesco Ciancio, Andrea Margara, Stefano Bonomi
Demand for non-surgical rejuvenating procedure is constantly increasing due to the aging population, increasing expense of aesthetics and beauty procedures, introduction of new applications and rising demand for noninvasive aesthetic procedures over surgical procedures. Skin necrosis is a rare but severe potential complication. It is caused by impediment of the blood supply to the skin area by compression and/or obstruction of the vessel with filler material, and/or direct injury to the vessel. We report the case of a young patient who presented an acute and severe complication after a dermal filler injection by an unlicensed therapist...
May 31, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28547293/nonsurgical-facial-rejuvenation-outcomes-and-safety-of-neuromodulator-and-soft-tissue-filler-procedures-performed-in-a-resident-cosmetic-clinic
#16
Ali A Qureshi, Rajiv P Parikh, Ketan Sharma, Terence M Myckatyn, Marissa M Tenenbaum
BACKGROUND: The ability to perform nonsurgical facial rejuvenation procedures is a core competency requirement for plastic surgery residents. However, limited data exist on training models to achieve competency in nonsurgical facial rejuvenation and on outcomes of these procedures performed by residents. The purpose here is to evaluate patient-reported outcomes and safety of nonsurgical facial rejuvenation procedures performed by plastic surgery residents. METHODS: We prospectively enrolled 50 patients undergoing neuromodulator and/or soft-tissue filler injections in a resident cosmetic clinic between April and August 2016...
May 25, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28538070/one-stage-treatment-for-adult-patients-with-crouzonoid-appearance-by-orthognathic-and-face-contouring-surgery
#17
Byung Jun Kim, Hahn Sol Bae, Yoonho Lee
Crouzon syndrome is a rare genetic disorder with autosomal-dominant inheritance that shows a triad of hallmark characteristics: craniosynostosis, exophthalmos, and midface retrusion. General treatment protocol for patients with Crouzon syndrome has already been established, but there is no standard treatment strategy for adult patients with Crouzonoid appearance. The authors present clinical patients of 1-stage orthognathic and face contouring surgery to achieve functional and aesthetic improvement.One-stage surgery was performed in adult patients with Crouzonoid appearance without a history of facial surgery...
May 19, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28449190/consensus-statement-on-prevention-and-management-of-adverse-effects-following-rejuvenation-procedures-with-hyaluronic-acid-based-fillers
#18
REVIEW
W G Philipp-Dormston, D Bergfeld, B M Sommer, G Sattler, S Cotofana, P Snozzi, U Wollina, K P J Hoffmann, C Salavastru, K Fritz
Facial fillers play an important role in the correction of facial changes associated with ageing. They offer quick treatments in the outpatient setting with minimal subsequent downtime that provide predictable, natural-looking, long-lasting results. Adverse reactions after hyaluronic acid injections tend to be mild or moderate and rather temporary. However, as with all injected or implanted biomaterials, severe adverse events can occur and patients must be fully informed of potential risks prior to undergoing treatment...
April 27, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28445360/facial-danger-zones-techniques-to-maximize-safety-during-soft-tissue-filler-injections
#19
Jack F Scheuer, David A Sieber, Ronnie A Pezeshk, Andrew A Gassman, Carey F Campbell, Rod J Rohrich
Given the short recovery and immediate results, facial fillers have become a popular alternative to surgical rejuvenation of the face. Reported complications arising from facial filler injections include erythema, tissue loss, blindness, stroke, and even death. In this article, the authors describe their anatomically based techniques to minimize risk and maximize safety when injecting in the facial danger zones, including the glabella/brow, temporal region, perioral region, nasolabial fold, nose, and infraorbital region...
May 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28432417/exploring-the-possibility-of-a-retrograde-embolism-pathway-from-the-facial-artery-to-the-ophthalmic-artery-system-in-vivo
#20
Hui Zheng, Lihong Qiu, Zonghui Liu, Yingjun Su, Xinyuan Pan, Sha Liu, Chenggang Yi
BACKGROUND: Blindness caused by soft tissue fillers is an extremely low-probability event, but it results in great concern because of its devastating consequences. Currently, the mechanism of an embolism is usually considered to be an accidental injection of fillers into the blood vessels of the face, such as a facial artery, and then retrograding into the ophthalmic artery system, which causes retinal ischemic necrosis. In addition, previous studies have shown that there are anastomoses between facial arteries and branches of the ophthalmic artery in cadavers...
April 21, 2017: Aesthetic Plastic Surgery
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