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Karina Sanches Machado d'Almeida, Stefanny Ronchi Spillere, Priccila Zuchinali, Gabriela Corrêa Souza
BACKGROUND: Heart failure (HF) is a complex syndrome and is recognized as the ultimate pathway of cardiovascular disease (CVD). Studies using nutritional strategies based on dietary patterns have proved to be effective for the prevention and treatment of CVD. Although there are studies that support the protective effect of these diets, their effects on the prevention of HF are not clear yet. METHODS: We searched the Medline, Embase, and Cochrane databases for studies that examined dietary patterns, such as dietary approaches to stop hypertension (DASH diet), paleolithic, vegetarian, low-carb and low-fat diets and prevention of HF...
January 10, 2018: Nutrients
Meenakshi Ravichandran, Gerald Grandl, Michael Ristow
The prospective cohort study, named PURE, found that in >135,000 participants from 18 countries, nutritive carbohydrates increase human mortality, whereas dietary fat reduces it, requesting a fundamental change of current nutritional guidelines. Experimental evidence from animal models provides synergizing mechanistic concepts as well as pharmacological options to mimic low-carb or ketogenic diets.
October 3, 2017: Cell Metabolism
Holly M Brown-Borg
Dietary interventions are simple, non-invasive tools that can be utilized to improve health and lifespan. In this issue, Roberts et al. (2017) and Newman et al. (2017) reveal the physiological benefits of feeding mice ketogenic diets and suggest different underlying mechanisms that may promote healthy aging.
September 5, 2017: Cell Metabolism
Arne Astrup, Mads F Hjorth
No abstract text is available yet for this article.
August 2017: EBioMedicine
Hiroshi Ohira, Brian Mc Ardle, Robert A deKemp, Pablo Nery, Daniel Juneau, Jennifer M Renaud, Ran Klein, Owen Clarkin, Karen MacDonald, Eugene Leung, Girish Nair, Rob Beanlands, David Birnie
Recent studies have reported the usefulness of (18)F-FDG PET in aiding with the diagnosis and management of patients with cardiac sarcoidosis (CS). However, image interpretation of (18)F-FDG PET for CS is sometimes challenging. We sought to investigate the inter- and intraobserver agreement and explore factors that led to important discrepancies between readers. Methods: We studied consecutive patients with no significant coronary artery disease who were referred for assessment of CS. Two experienced readers masked to clinical information, imaging reports, independently reviewed (18)F-FDG PET/CT images...
August 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
H Braun
Nutrition has a crucial influence on physical and mental performance ability and is an important measure along sidetraining in high-performance athletes. However, this form of nutritionis not applicable for every athlete and in every situation. The question of optimal nutrition requires involvement with the particular type of sports, an athlete's current training stage, and athletes' individual requirements and objectives. Implementation takes time and individual motivation on the part of athletes and the specialist staff who engage intensively with the nutritional needs of athletes...
August 2016: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
Ellinor Fredriksson, Hilde Kristin Brekke, Lars Ellegård
BACKGROUND: The dietary intake in Swedish medical students has been reported for the periods 1987-1993 and 1994-2006. OBJECTIVE: To analyse dietary intake in medical students between 2007 and 2012, in relation to Nordic Nutrition Recommendations, to previous surveys and to a contemporary Swedish population. DESIGN: Nutrient intake was calculated from 3-day food records conducted by 698 medical students. The differences between surveys were evaluated using a t-test and the changes over time by linear regression...
February 2016: Scandinavian Journal of Public Health
Caroline M Apovian
No abstract text is available yet for this article.
October 2015: American Journal of Clinical Nutrition
Diane E Grise, Heath M McAllister, Jeffrey Langland
This case report demonstrates a successful approach to managing patients with type 2 diabetes mellitus (DM2). Botanical herbs (including Gymnema sylvestre) and nutrients (including alpha lipoic acid and chromium) were used alongside metformin to help improve insulin sensitization; however, the greatest emphasis of treatment for this patient centered on a low-carbohydrate, whole-foods diet and regular exercise that shifted the focus to the patient's role in controlling their disease. Research on DM2 often focuses on improving drug efficacy while diet and lifestyle are generally overlooked as both a preventive and curative tool...
May 2015: Global Advances in Health and Medicine: Improving Healthcare Outcomes Worldwide
H Bobby Fokidis, Mei Yieng Chin, Victor W Ho, Hans H Adomat, Kiran K Soma, Ladan Fazli, Ka Mun Nip, Michael Cox, Gerald Krystal, Amina Zoubeidi, Emma S Tomlinson Guns
Dietary factors continue to preside as dominant influences in prostate cancer prevalence and progression-free survival following primary treatment. We investigated the influence of a low carbohydrate diet, compared to a typical Western diet, on prostate cancer (PCa) tumor growth in vivo. LNCaP xenograft tumor growth was studied in both intact and castrated mice, representing a more advanced castration resistant PCa (CRPC). No differences in LNCaP tumor progression (total tumor volume) with diet was observed for intact mice (P = 0...
June 2015: Journal of Steroid Biochemistry and Molecular Biology
Sebene Mayorandan, Uta Meyer, Hans Hartmann, Anibh Martin Das
BACKGROUND: Frequent feeds with carbohydrate-rich meals or continuous enteral feeding has been the therapy of choice in glycogen storage disease (Glycogenosis) type III. Recent guidelines on diagnosis and management recommend frequent feedings with high complex carbohydrates or cornstarch avoiding fasting in children, while in adults a low-carb-high-protein-diet is recommended. While this regimen can prevent hypoglycaemia in children it does not improve skeletal and heart muscle function, which are compromised in patients with glycogenosis IIIa...
2014: Orphanet Journal of Rare Diseases
C D Gardner
Although the 'Low-Fat' diet was the predominant public health recommendation for weight loss and weight control for the past several decades, the obesity epidemic continued to grow during this time period. An alternative 'low-carbohydrate' (Low-Carb) approach, although originally dismissed and even vilified, was comparatively tested in a series of studies over the past decade, and has been found in general to be as effective, if not more, as the Low-Fat approach for weight loss and for several related metabolic health measures...
July 2012: International Journal of Obesity Supplements
S Martin, K Kempf
HISTORY AND ADMISSION FINDINGS: Case 1: 59-year-old man with newly diagnosed type 2 diabetes mellitus. Case 2: 69-year-old woman with poorly controlled type 2 diabetes mellitus. INVESTIGATIONS: Case 1: BMI 36,8 kg/m2. Biochemical evaluation were normal except elevated transaminases. Case 2: BMI 37,0 kg/m2. Abdominal ultrasound showed a fatty liver. THERAPY AND FOLLOW UP: Both patients underwent a 12-week interven tion with a formula diet. In the first week the three principle meals were replaced by the formular diet...
May 2014: Deutsche Medizinische Wochenschrift
Antonio Paoli, Antonino Bianco, Keith A Grimaldi, Alessandra Lodi, Gerardo Bosco
Weight loss protocols can only be considered successful if they deliver consistent results over the long term-a goal which is often elusive, so much so that the term "yo-yo" is used to describe the perennial weight loss/weight regain battle common in obesity. We hypothesized that a ketogenic Mediterranean diet with phytoextracts (KEMEPHY) combined with the acknowledged health benefits of traditional Mediterranean nutrition may favor long term weight loss. We analysed 89 male and female obese subjects, aged between 25 and 65 years who were overall healthy apart from being overweight...
December 18, 2013: Nutrients
Eveline A P Martens, Margriet S Westerterp-Plantenga
PURPOSE OF REVIEW: The review addresses briefly the relevance of protein diets for body weight loss and weight maintenance. The addition of recent findings on age-dependent protein requirements, specific effects of protein intake and protein source, the relevance of the other dietary macronutrients, especially of 'low-carb', 'protein leverage', the mechanisms of protein-induced satiety, and food-reward makes the review up-to-date. RECENT FINDINGS: Different effects of protein diets in different age groups result from age-dependent protein requirements that are primarily related to effects on body composition...
January 2014: Current Opinion in Clinical Nutrition and Metabolic Care
Michael E Peterson
Xylitol is a prevalent sugar substitute found in a wide variety of foods, particularly those labeled as "low carb." It is found in many medicines and dental products both for its antibacterial activity and to increase palatability. Originally, this toxin was recognized as a problem in dogs following sugarless gum ingestions. Xylitol is generally nontoxic to mammals except for dogs. In the dog, xylitol induces marked increases in insulin production and occasionally hepatopathy. The clinical syndrome is manifested with signs consistent with profound hypoglycemia, hypokalemia, hypophosphatemia, and acute hepatic failure...
February 2013: Topics in Companion Animal Medicine
Monica Baumann, Martine Z Espeland, Ane Sørlie Kværner, Martin Prøven Bogsrud, Kjetil Retterstøl
BACKGROUND: Many Norwegians have embraced the low-carb trend and choose butter and bacon instead of brown bread and carrots. This entails a dramatic change in the total intake of fat and the intake of saturated fat. We have investigated how a low-carb diet can affect the lipid profile in healthy adults with a normal bodyweight. MATERIAL AND METHOD: Seven healthy female participants with normal bodyweight underwent a four-week trial of a low-carb diet (< 20-25 grams of carbohydrates/day)...
June 11, 2013: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
Louise A McKenna, Russell S Drummond, Suzannah Drummond, Dinesh Talwar, Michael E J Lean
No abstract text is available yet for this article.
May 1, 2013: BMJ: British Medical Journal
Edward L LaGory, Amato J Giaccia
No abstract text is available yet for this article.
March 1, 2013: Cell Cycle
Claudia Zok
No abstract text is available yet for this article.
September 2012: Deutsche Medizinische Wochenschrift
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