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Trans pulmonary pressure

Sina Moradmand Badie, Mehrnaz Rasoulinejad, Mohammadreza Salehi, Hamid Emadi Kochak, SeyedAhmad SeyedAlinaghi, Seyed Ali Dehghan Manshadi, Fatemeh Jahanjo Amin Abad, Banafsheh Moradmand Badie
BACKGROUND: Echocardiography is a reliable means for the diagnosis of functional and valvular diseases of the heart in HIV positive and HIV negative patients. The current study was to evaluate echocardiographic abnormalities in HIV positive patients under an antiretroviral therapy (ART) program in Tehran, Imam Khomeini Hospital, Iran. METHODS: This is a descriptive cross-sectional study, conducted among 231 HIV positive patients under ART. All HIV positive patients including 150 men (65%) and 81 women (35%) (mean age of 41 years) were assessed by trans-thoracic echocardiography (TTE) in Imam Khomeini Hospital, over the period from 2013 to 2014...
December 5, 2016: Infectious Disorders Drug Targets
Heba Talat Mahmoud, Giuseppe Santoro, Gianpiero Gaio, Fabio Angelo D'Aiello, Cristina Capogrosso, Maria Teresa Palladino, Maria Giovanna Russo
OBJECTIVES: This study aimed to report a large, single-center experience of percutaneous arterial duct (AD) closure using Amplatzer Duct Occluder II Additional Sizes device (ADO II-AS)(St. Jude Medical Corp, St. Paul, MN, USA). BACKGROUND: Transcatheter closure of AD remains challenging in low body weight patients and those who have a persisting shunt following a previous attempt at interventional closure. Recent technical advances in device design may address these issues...
November 10, 2016: Catheterization and Cardiovascular Interventions
L X Xie, F Xie
No abstract text is available yet for this article.
September 2016: Chinese Journal of Tuberculosis and Respiratory Diseases
Jochen Steppan, Huong T Tran, Valeriani R Bead, Young Jun Oh, Gautam Sikka, Trinity J Bivalacqua, Arthur L Burnett, Dan E Berkowitz, Lakshmi Santhanam
BACKGROUND: In sickle cell disease (SCD), hemolysis results in the release and activation of arginase, an enzyme that reciprocally regulates nitric oxide (NO) synthase activity and thus, NO production. Simply supplementing the common substrate L-arginine, however, fails to improve NO bioavailability. In this study, we tested the hypothesis that arginase inhibition would improve NO bioavailability and thereby attenuate systemic and pulmonary vascular endothelial dysfunction in transgenic mice with SCD...
September 2016: Anesthesia and Analgesia
David N Wilson, Sydney E Schacht, Layla Al-Nakkash, Jeganathan Ramesh Babu, Tom L Broderick
Pulmonary hypertension (PAH) is characterized by abnormal vascular remodeling and increased pulmonary artery pressure which lead to right ventricular (RV) hypertrophy and heart failure. Resveratrol (3,5,4'-trihydroxy-trans-stilbene), a dietary polyphenol found in the skins and seeds of grapes, has been found to have antioxidant, anti-proliferative and anti-fibrotic effects. This study examined the effects of resveratrol on cardiac and pulmonary trunk remodeling, and common plasma markers of vascular function in rats with PAH was induced in male Sprague-Dawley rats by a single subcutaneous injection of monocrotaline (MCT, 60mg/kg)...
May 27, 2016: Pathophysiology: the Official Journal of the International Society for Pathophysiology
Leonardo M Del Grande, Fernando A M Herbella, Amilcar M Bigatao, Jose R Jardim, Marco G Patti
BACKGROUND: Chronic obstructive pulmonary disease (COPD) patients have a high incidence of gastroesophageal reflux disease (GERD) whose pathophysiology seems to be linked to an increased trans-diaphragmatic pressure gradient and not to a defective esophagogastric barrier. Inhaled beta agonist bronchodilators are a common therapy used by patients with COPD. This drug knowingly not only leads to a decrease in the lower esophageal sphincter (LES) resting pressure, favoring GERD, but also may improve ventilatory parameters, therefore preventing GERD...
October 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
(no author information available yet)
No abstract text is available yet for this article.
June 2016: Annals of Intensive Care
G E M Reeves, N Collins, P Hayes, J Knapp, M Squance, H Tran, B Bastian
Pulmonary artery hypertension (PAH) is a disorder of elevated resistance in the pulmonary arterial vessels, reflected by elevation of measured pulmonary artery pressure (PAP), and presenting with breathlessness and, if untreated, progressing to right heart failure and death. The heightened prevalence of PAH in populations with underlying systemic autoimmune conditions, particularly scleroderma and its variants, is well recognised, consistent with the proposed autoimmune contribution to PAH pathogenesis, along with disordered thrombotic, inflammatory, and mitogenic factors...
2016: International Journal of Rheumatology
Judith Kramer, Simon Biner, Michael Ghermezi, Gregg S Pressman, Hezzi Shmueli, Jason Shimiaie, Arie Finkelstein, Shmuel Banai, Arie Steinvil, Eric Buffle, Galit Aviram, Meirav Ingbir, Nahum Nesher, Gad Keren, Yan Topilsky
AIM: To assess the impact of left ventricular (LV) filling parameters on outcomes following trans-catheter aortic valve replacement (TAVR). METHODS AND RESULTS: A total of 526 TAVR patients were compared with 300 patients with severe aortic stenosis (AS) treated conservatively. Clinical variables were collected along with echocardiographic data at baseline, 1 month, and 6 months after study entry. End points included all-cause mortality and the combination of death and heart failure admission...
May 10, 2016: European Heart Journal Cardiovascular Imaging
Chi-Ling Joanna Sinn, Jake Tran, Tim Pauley, John Hirdes
PURPOSE OF STUDY: The purpose was to identify risk and protective factors assessed at complex continuing care (CCC) admission that were associated with three adverse outcomes (death, readmission, and incidence of or failure to improve possible depression) for persons discharged from CCC to the community with home care services. PRIMARY PRACTICE SETTINGS: CCC, home care, community. METHODOLOGY AND SAMPLE: The sample included all CCC patients in Ontario assessed with the Resident Assessment Instrument-Minimum Data Set 2...
May 2016: Professional Case Management
Nicolas Pereira, Carlos Sciaraffia, Stefan Danilla, Francisco Parada, Constanza Asfora, César Moral
BACKGROUND: Abdominal wall weakness is a consequence of rectus abdominis diastasis and flaccidity of the myofascial component. A degree of plicature of the rectus abdominis generates an increase of intra-abdominal pressure (IAP), which may result in an increase of intrathoracic pressure, thus affecting thoracic hemodynamics and leading to inadequate ventilation. OBJECTIVES: To assess changes generated by plicature of the rectus abdominis on IAP and pulmonary function in patients undergoing abdominoplasty...
June 2016: Aesthetic Surgery Journal
Tomoaki Shiba, Mao Takahashi, Ryuya Hashimoto, Tadashi Matsumoto, Yuichi Hori
PURPOSE: To determine whether a pulse waveform analysis in the optic nerve head (ONH) circulation as determined by laser speckle flowgraphy (LSFG) can provide systemic hemodynamic values - the systemic vascular resistance (SVR) in particular - similar to those obtained by using a Swan-Ganz catheter, which is an invasive method. METHOD: Sixteen consecutive subjects were examined. Hemodynamic monitoring was obtained from right heart catheterization with a Swan-Ganz catheter and coronary angiography without an intracoronary nitroglycerin administration...
June 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
Rieko Yoshiyuki, Ryo Tanaka, Ryuji Fukushima, Noboru Machida
The present study aimed to evaluate the preventive effect of sildenafil treatment on pulmonary hypertension (PH) induced by monocrotaline (MCT) in rats. Fifty-four 12-week-old male Sprague-Dawley rats were injected with MCT or saline solution (MCT-injected rats: n=36; saline: n=18). Serial echocardiography and right ventricular systolic pressure (RVSP) measurements via a cardiac catheter were performed at 2, 4 and 6 weeks after the injection. After injection of MCT, rats received oral sildenafil (MCT/sildenafil group: n=18) or no treatment (MCT group: n=18) until undergoing echocardiography and cardiac catheterization...
July 29, 2016: Experimental Animals
In Jeong Cho, Geu Ru Hong, Seung Hyun Lee, Sak Lee, Byung Chul Chang, Chi Young Shim, Hyuk Jae Chang, Jong Won Ha, Namsik Chung
PURPOSE: The incidence of prosthesis-patient mismatch (PPM) after mitral valve replacement (MVR) has been reported to vary. The purpose of the current study was to investigate incidence of PPM according to the different methods of calculating effective orifice area (EOA), including the continuity equation (CE), pressure half time (PHT) method and use of reference EOA, and to compare these with various echocardiographic variables. MATERIALS AND METHODS: We retrospectively reviewed 166 individuals who received isolated MVR due to rheumatic mitral stenosis and had postoperative echocardiography performed between 12 and 60 months after MVR...
March 2016: Yonsei Medical Journal
Luciano Gattinoni, John J Marini, Antonio Pesenti, Michael Quintel, Jordi Mancebo, Laurent Brochard
The baby lung was originally defined as the fraction of lung parenchyma that, in acute respiratory distress syndrome (ARDS), still maintains normal inflation. Its size obviously depends on ARDS severity and relates to the compliance of the respiratory system. CO2 clearance and blood oxygenation primarily occur within the baby lung. While the specific compliance suggests the intrinsic mechanical characteristics to be nearly normal, evidence from positron emission tomography suggests that at least a part of the well-aerated baby lung is inflamed...
May 2016: Intensive Care Medicine
Neil Duplantier, Michael Couch, Logan Emory, Joseph Zavatsky
STUDY DESIGN: Outcomes measurement OBJECTIVE: Describe the occurrence of cardiac emboli recorded on trans-esophageal echocardiogram (TEE) after the injection of a topical hemostatic agent into a vertebra prior to performing a pedicle subtraction osteotomy (PSO). SUMMARY OF BACKGROUND DATA: Hemostasis during spinal surgery is critical for adequate visualization and to reduce the risk of peri-operative complications. Adult spinal deformity (ASD) surgery can involve performing PSOs which are useful in cases of fixed spinal deformities and are associated with increased blood loss secondary to epidural and cancellous bleeding...
November 30, 2015: Spine
Y Xin, J-Q Lv, Y-Z Wang, J Zhang, X Zhang
The effect of all-trans retinoic acid (ATRA) on the expression of α-smooth muscle actin (α-SMA) in rats with pulmonary arterial hypertension (PAH) was studied, and the mechanism of the effect of ATRA on PAH was proposed. Thirty male SD rats were randomly divided into normal control, monocrotaline (MCT) model, and ATRA [30 mg/(]intervention groups (N = 10 each). The mean pulmonary arterial pressure was recorded. Right ventricular hypertrophy index (RVHI) was calculated (weight of right ventricle: total weight of left ventricle and interventricular septum)...
2015: Genetics and Molecular Research: GMR
Valeria Cammalleri, Francesco Romeo, Gian Paolo Ussia
Transcatheter edge-to-edge mitral valve repair with MitraClip System (Abbott Vascular, Menlo Park, CA) needs a trans-septal access for positioning the 22-Fr guiding catheter in the left atrium. To the best of our knowledge no data are currently available about the hemodynamic consequences of a congenital atrial septal defect (ASD) after MitraClip repair. We report a case of MitraClip repair in a patient with ostium secundum ASD and ischemic cardiomyopathy, who needed intraprocedural closure of the defect for serious hemodynamic complications, secondary to worsening of the right ventricular function, increased pulmonary pressure and inversion of the interatrial shunt in right-to-left direction...
August 2016: Catheterization and Cardiovascular Interventions
Kyle W Eudailey, Soo Youn Yi, Linda Bodnar Mongero, Gebhard Wagener, James V Guarrera, Isaac George
Extracorporeal membrane oxygenation (ECMO) has proven to be an invaluable method of cardiopulmonary support in cases of severe cardiogenic shock. In an emergency, femoral artery and vein cannulation is the easiest and quickest access to initiate support. Often, with peripheral venous-arterial ECMO (VA ECMO), an inadequate reduction in left ventricular end-diastolic pressure (LVEDP) is present secondary to increased afterload from retrograde flow, inadequate RV drainage or persistent bronchial circulation. Elevated LVEDP has been known to be associated with poor myocardial recovery, LV thrombus formation and significant pulmonary edema...
November 2015: Perfusion
Jay M Reimer, Zeeshan H Syedain, Bee H T Haynie, Robert T Tranquillo
Pediatric patients account for a small portion of the heart valve replacements performed, but a pediatric pulmonary valve replacement with growth potential remains an unmet clinical need. Herein we report the first tubular heart valve made from two decellularized, engineered tissue tubes attached with absorbable sutures, which can meet this need, in principle. Engineered tissue tubes were fabricated by allowing ovine dermal fibroblasts to replace a sacrificial fibrin gel with an aligned, cell-produced collagenous matrix, which was subsequently decellularized...
September 2015: Biomaterials
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