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https://www.readbyqxmd.com/read/27873024/p4%C3%A2-medicine-and-osteoporosis-a%C3%A2-systematic-review
#1
REVIEW
Klemen Kodrič, Klemen Čamernik, Darko Černe, Radko Komadina, Janja Marc
BACKGROUND: Osteoporosis is the most frequent bone metabolic disease. In order to improve early detection, prediction, prevention, diagnosis, and treatment of the disease, a new model of P4 medicine (personalized, predictive, preventive, and participatory medicine) could be applied. The aim of this work was to systematically review the publications of four different types of "omics" studies related to osteoporosis, in order to discover novel predictive, preventive, diagnostic, and therapeutic targets for better management of the geriatric population...
November 21, 2016: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/27864206/educational-strategies-to-enable-expansion-of-pharmacogenomics-based-care
#2
Kristin Wiisanen Weitzel, Christina L Aquilante, Samuel Johnson, David F Kisor, Philip E Empey
PURPOSE: The current state of pharmacogenomics education for pharmacy students and practitioners is discussed, and resources and strategies to address persistent challenges in this area are reviewed. SUMMARY: Consensus-based pharmacist competencies and guidelines have been published to guide pharmacogenomics knowledge attainment and application in clinical practice. Pharmacogenomics education is integrated into various pharmacy school courses and, increasingly, into Pharm...
December 1, 2016: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/27822876/leaves-imitate-trees-minnesota-hmong-concepts-of-heredity-and-applications-to-genomics-research
#3
Kathleen A Culhane-Pera, MaiKia Moua, Pachia Vue, Kang Xiaaj, May Xia Lo, Robert J Straka
Historically, Hmong refugees in the USA were distrustful of Western medicine, medicines, and medical research due to concerns about harm and experimentation. Current Hmong concerns about genomics research are not well known. Our research aims were to identify cultural and ethical issues about conducting genomic studies in the Hmong community. Using a community-based participatory action process, the West Side Hmong Genomics Research Board conducted a qualitative exploratory research study that included semistructured interviews with five Hmong key informants and five focus groups with 42 Hmong adults near Saint Paul, Minnesota...
November 7, 2016: Journal of Community Genetics
https://www.readbyqxmd.com/read/27809825/becoming-partners-retaining-autonomy-ethical-considerations-on-the-development-of-precision-medicine
#4
Alessandro Blasimme, Effy Vayena
Precision medicine promises to develop diagnoses and treatments that take individual variability into account. According to most specialists, turning this promise into reality will require adapting the established framework of clinical research ethics, and paying more attention to participants' attitudes towards sharing genotypic, phenotypic, lifestyle data and health records, and ultimately to their desire to be engaged as active partners in medical research.Notions such as participation, engagement and partnership have been introduced in bioethics debates concerning genetics and large-scale biobanking to broaden the focus of discussion beyond individual choice and individuals' moral interests...
November 4, 2016: BMC Medical Ethics
https://www.readbyqxmd.com/read/27776531/integrating-precision-cancer-medicine-into-healthcare-policy-practice-and-research-challenges
#5
Gabrielle Bertier, Jian Carrot-Zhang, Vassilis Ragoussis, Yann Joly
Precision medicine (PM) can be defined as a predictive, preventive, personalized, and participatory healthcare service delivery model. Recent developments in molecular biology and information technology make PM a reality today through the use of massive amounts of genetic, 'omics', clinical, environmental, and lifestyle data. With cancer being one of the most prominent public health threats in developed countries, both the research community and governments have been investing significant time, money, and efforts in precision cancer medicine (PCM)...
October 24, 2016: Genome Medicine
https://www.readbyqxmd.com/read/27763468/cultural-health-assets-of-somali-and-oromo-refugees-and-immigrants-in-minnesota-findings-from-a-community-based-participatory-research-project
#6
Elizabeth Lightfoot, Jennifer Blevins, Terry Lum, Amano Dube
This community-based participatory research study sought to identify the cultural health assets of the Somali and Oromo communities in one Minnesota neighborhood that could be mobilized to develop culturally appropriate health interventions. Community asset mappers conducted 76 interviews with Somali and Oromo refugees in in Minnesota regarding the cultural assets of their community. A community-university data analysis team coded data for major themes. Key cultural health assets of the Somali and Oromo refugee communities revealed in this study include religion and religious beliefs, religious and cultural practices, a strong culture of sharing, interconnectedness, the prominence of oral traditions, traditional healthy eating and healthy lifestyles, traditional foods and medicine, and a strong cultural value placed on health...
2016: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/27747816/a-tamper-proof-audit-and-control-system-for-the-doctor-in-the-loop
#7
Peter Kieseberg, Bernd Malle, Peter Frühwirt, Edgar Weippl, Andreas Holzinger
The "doctor in the loop" is a new paradigm in information-driven medicine, picturing the doctor as authority inside a loop supplying an expert system with information on actual patients, treatment results, and possible additional (side-)effects, including general information in order to enhance data-driven medical science, as well as giving back treatment advice to the doctor himself. While this approach can be very beneficial for new medical approaches like P4 medicine (personal, predictive, preventive, and participatory), it also relies heavily on the authenticity of the data and thus increases the need for secure and reliable databases...
December 2016: Brain Informatics
https://www.readbyqxmd.com/read/27744374/the-tribal-tobacco-education-and-policy-initiative-findings-from-a-collaborative-participatory-evaluation
#8
Sheryl Scott, Joanne D'Silva, Carol Hernandez, Nicole Toves Villaluz, Jaime Martinez, Chris Matter
While the reduction in the overall U.S. smoking prevalence has been declared one of the top 10 public health achievements of the past century, the growing disparity in smoking between American Indians and the general population is one of the biggest challenges of the 21st century. Minnesota in particular has very high smoking rates among American Indians (59%). Tribal Nations in Minnesota share a past of attempted cultural genocide and a present of restoring the strength of their cultural teachings, including the prominence of traditional tobacco as a sacred "first medicine...
October 14, 2016: Health Promotion Practice
https://www.readbyqxmd.com/read/27649992/from-the-anticipatory-corpse-to-the-participatory-body
#9
M Therese Lysaught
Jeffrey Bishop's The Anticipatory Corpse demonstrates how death is present in and cloaked by contemporary practices of end-of-life care. A key to Bishop's argument is that for modern medicine the cadaver has become epistemologically normative and that a metaphysics shorn of formal and final causes now shapes contemporary healthcare practices. The essays of this symposium laud and interrogate Bishop's argument in three ways. First, they raise critical methodological challenges from the perspectives of human rights, Charles Taylor's concept of social imaginaries, and economics...
September 20, 2016: Journal of Medicine and Philosophy
https://www.readbyqxmd.com/read/27649826/from-personalized-to-precision-medicine-the-ethical-and-social-implications-of-rhetorical-reform-in-genomic-medicine
#10
Eric Juengst, Michelle L McGowan, Jennifer R Fishman, Richard A Settersten
Since the late 1980s, the human genetics and genomics research community has been promising to usher in a "new paradigm for health care"-one that uses molecular profiling to identify human genetic variants implicated in multifactorial health risks. After the completion of the Human Genome Project in 2003, a wide range of stakeholders became committed to this "paradigm shift," creating a confluence of investment, advocacy, and enthusiasm that bears all the marks of a "scientific/intellectual social movement" within biomedicine...
September 2016: Hastings Center Report
https://www.readbyqxmd.com/read/27638683/personalized-medicine-evidence-of-normativity-in-its-quantitative-definition-of-health
#11
Henrik Vogt, Bjørn Hofmann, Linn Getz
Systems medicine, which is based on computational modelling of biological systems, is emerging as an increasingly prominent part of the personalized medicine movement. It is often promoted as 'P4 medicine' (predictive, preventive, personalized, and participatory). In this article, we test promises made by some of its proponents that systems medicine will be able to develop a scientific, quantitative metric for wellness that will eliminate the purported vagueness, ambiguity, and incompleteness-that is, normativity-of previous health definitions...
October 2016: Theoretical Medicine and Bioethics
https://www.readbyqxmd.com/read/27586388/exploiting-indigenous-knowledge-of-subsistence-farmers-for-the-management-and-conservation-of-enset-ensete-ventricosum-welw-cheesman-musaceae-family-diversity-on-farm
#12
Zerihun Yemataw, Kassahun Tesfaye, Awole Zeberga, Guy Blomme
BACKGROUND: Enset (Ensete ventricosum (Welw.) Cheesman) belongs to the order sctaminae, the family musaceae. The Musaceae family is subdivided into the genera Musa and Ensete. Enset is an important staple crop for about 20 million people in the country. Recent publications on enset ethnobotany are insignificant when compared to the diverse ethnolingustic communities in the country. Hence, this paper try to identify and document wealth of indigenous knowledge associated with the distribution, diversity, and management of enset in the country...
2016: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/27577454/participatory-heuristic-evaluation-of-the-second-iteration-of-the-ewall-interface-application
#13
Stine Hangaard, Clara Schaarup, Ole K Hejlesen
The number of people having a chronic disease is increasing. Telehealth may provide an alternative to traditional medicine as telehealth solutions have shown to have a positive influence on quality of live and to decrease the number of hospital visits. A new telehealth solution is the eWALL system. Previously, the eWALL interface application has been evaluated using participatory heuristic evaluation (PHE). The previous round of PHE lead to drastic changes of the eWALL interface application. Consequently, a second round of PHE was performed...
2016: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/27546358/the-p4-health-spectrum-a-predictive-preventive-personalized-and-participatory-continuum-for-promoting-healthspan
#14
Michael Sagner, Amy McNeil, Pekka Puska, Charles Auffray, Nathan D Price, Leroy Hood, Carl J Lavie, Ze-Guang Han, Zhu Chen, Samir Kumar Brahmachari, Bruce S McEwen, Marcelo B Soares, Rudi Balling, Elissa Epel, Ross Arena
Chronic diseases (i.e., noncommunicable diseases), mainly cardiovascular disease, cancer, respiratory diseases and type-2-diabetes, are now the leading cause of death, disability and diminished quality of life on the planet. Moreover, these diseases are also a major financial burden worldwide, significantly impacting the economy of many countries. Healthcare systems and medicine have progressively improved upon the ability to address infectious diseases and react to adverse health events through both surgical interventions and pharmacology; we have become efficient in delivering reactive care (i...
August 18, 2016: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/27536722/experiential-learning-through-participatory-action-research-in-public-health-supports-community-based-training-of-future-health-professionals
#15
Lisa K Marriott, Adam C Lipus, Laurie Choate, Jamie Smith, Leigh Coppola, William E Cameron, Jackilen Shannon
Engaging community members in research can help cultivate effective partnerships while providing experiential training and continuing education opportunities. Several studies have involved communities in this way, though many have been small in the scale of community involvement or have included little detail of the institutional review board process by which community members became approved researchers in the study. This article presents findings on an evaluation of the training procedures and experiences of 703 first-time community-based volunteer researchers who were recruited in their communities and trained on-site to enroll research participants, collect data, and provide individualized consultation of results at travelling health education and research fairs...
December 2015: Pedagogy in Health Promotion
https://www.readbyqxmd.com/read/27523651/the-new-role-of-biomedical-informatics-in-the-age-of-digital-medicine
#16
Fernando J Martin-Sanchez, Guillermo H Lopez-Campos
OBJECTIVES: To reflect on the recent rise of Digital Medicine, as well as to analyse main research opportunities in this area. Through the use of several examples, this article aims to highlight the new role that Biomedical Informatics (BMI) can play to facilitate progress in research fields such as participatory and precision medicine. This paper also examines the potential impact and associated risks for BMI due to the development of digital medicine and other recent trends. Lastly, possible strategies to place BMI in a better position to face these challenges are suggested...
October 17, 2016: Methods of Information in Medicine
https://www.readbyqxmd.com/read/27516651/a-review-of-herbal-medicine-in-iranian-traditional-manuscripts-for-treatment-of-participatory-gastric-headache
#17
Mehrnaz Jafarpour, Gholamhossein Yousefi, Azadeh Hamedi
BACKGROUND: Participatory gastric headache is a type of headache described in Iranian traditional medicine. It is defined as a headache not originated from the head and neck disorders; rather the pain in the head is caused by gastric dysfunction and its disorders. Treatment of this type of headache is completely reliant on the treatment of the gastric complaint. Reviewing Iranian traditional medicine (ITM) literature, a broad spectrum of herbal medicines that could be useful in the treatment of this type of headache is described...
May 2016: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27493630/animal-free-chemical-safety-assessment
#18
REVIEW
George D Loizou
The exponential growth of the Internet of Things and the global popularity and remarkable decline in cost of the mobile phone is driving the digital transformation of medical practice. The rapidly maturing digital, non-medical world of mobile (wireless) devices, cloud computing and social networking is coalescing with the emerging digital medical world of omics data, biosensors and advanced imaging which offers the increasingly realistic prospect of personalized medicine. Described as a potential "seismic" shift from the current "healthcare" model to a "wellness" paradigm that is predictive, preventative, personalized and participatory, this change is based on the development of increasingly sophisticated biosensors which can track and measure key biochemical variables in people...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27481321/community-based-participatory-research-understanding-a-promising-approach-to-addressing-knowledge-gaps-in-palliative-care
#19
Catherine Riffin, Cara Kenien, Angela Ghesquiere, Ashley Dorime, Carolina Villanueva, Daniel Gardner, Jean Callahan, Elizabeth Capezuti, M Carrington Reid
Concern over the need for effective and accessible healthcare for individuals with advanced chronic illness has drawn attention to the significant gaps in our knowledge of palliative medicine. To advance our understanding of this field, community-based participatory research (CBPR) is proposed as a tool for future research initiatives. This paper offers a rationale for how CBPR may be employed to address specific gaps in palliative care research. Several examples where this approach has been used previously are described, and potential obstacles to implementing this research method are delineated...
July 2016: Annals of Palliative Medicine
https://www.readbyqxmd.com/read/27448658/same-same-but-different-why-we-should-care-about-the-distinction-between-professionalism-and-ethics
#20
Sabine Salloch
Medical professionalism forms a belief system which is used to defend physicians' ethos against counterforces which might threaten the integrity of medical practice. The current debates on professionalism, however, are characterized by the lack of a clear distinction between professional and ethical aspects of physicians' conduct. This article argues that a differentiation between professionalism and ethics is not of mere academic interest. Instead, it is of great practical importance with regard to morally contentious issues in medicine...
2016: BMC Medical Ethics
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