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Magnesium sulfate and acute bronchiolitis

Khalid Alansari, Rafah Sayyed, Bruce L Davidson, Shahaza Al Jawala, Mohamed Ghadier
BACKGROUND: The goal of this study was to determine if IV magnesium, useful for severe pediatric asthma, reduces time to medical readiness for discharge in patients with bronchiolitis when added to supportive care. METHODS: We compared a single dose of 100 mg/kg of IV magnesium sulfate vs placebo for acute bronchiolitis. Patients received bronchodilator therapy, nebulized hypertonic saline, and 5 days of dexamethasone if there was eczema and/or a family history of asthma...
July 2017: Chest
Mohammad Reza Modaresi, Jamal Faghihinia, Roya Kelishadi, Mohsen Reisi, Shahrokh Mirlohi, Farhad Pajhang, Majid Sadeghian
In the original article, the authors failed to cite the study by Kose M et al. entitled "The efficacy of nebulized salbutamol, magnesium sulfate and salbutamol/magnesium sulfate combination in moderate bronchiolitis. Eur J Pediatr 2014;173: 1157-1160" as the first in literature to assess the efficacy of magnesium sulfate in the treatment of acute bronchiolitis. The authors apologize for this unintentional omission.
May 2016: Indian Journal of Pediatrics
Mohammad Reza Modaresi, Jamal Faghihinia, Roya Kelishadi, Mohsen Reisi, Shahrokh Mirlohi, Farhad Pajhang, Majid Sadeghian
OBJECTIVE: To assess the efficacy of nebulized magnesium sulfate as a bronchodilator in infants hospitalized with acute bronchiolitis. METHODS: This three-center double masked randomized clinical trial comprised 120 children with moderate to severe bronchiolitis. They were randomly assigned into two groups: the first group was treated with nebulized magnesium sulfate (40 mg/kg) and nebulized epinephrine (0.1 ml/kg) and the second group (control) was treated with nebulized epinephrine (0...
September 2015: Indian Journal of Pediatrics
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