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https://www.readbyqxmd.com/read/28208321/high-efficiency-%C3%AE-ray-flash-generation-via-multiple-laser-scattering-in-ponderomotive-potential-well
#1
Z Gong, R H Hu, Y R Shou, B Qiao, C E Chen, X T He, S S Bulanov, T Zh Esirkepov, S V Bulanov, X Q Yan
γ-ray flash generation in near-critical-density target irradiated by four symmetrical colliding laser pulses is numerically investigated. With peak intensities about 10^{23} W/cm^{2}, the laser pulses boost electron energy through direct laser acceleration, while pushing them inward with the ponderomotive force. After backscattering with counterpropagating laser, the accelerated electron is trapped in the electromagnetic standing waves or the ponderomotive potential well created by the coherent overlapping of the laser pulses, and emits γ-ray photons in a multiple-laser-scattering regime, where electrons act as a medium transferring energy from the laser to γ rays in the ponderomotive potential valley...
January 2017: Physical Review. E
https://www.readbyqxmd.com/read/28201890/structure-property-relationships-in-cubic-cuprous-iodide-a-novel-view-on-stability-chemical-bonding-and-electronic-properties
#2
A Pishtshev, S Zh Karazhanov
Based on the combination of density functional theory and theory-group methods, we performed systematic modeling of γ-CuI structural design at the atomistic level. Being started from the metallic copper lattice, we treated a crystal assembly as a stepwise iodination process characterized in terms of a sequence of intermediate lattice geometries. These geometries were selected and validated via screening of possible structural transformations. The genesis of chemical bonding was studied for three structural transformations by analyzing the relevant changes in the topology of valence electron densities...
February 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28178629/plasma-methionine-depletion-and-pharmacokinetic-properties-in-mice-of-methionine-%C3%AE-lyase-from-citrobacter-freundii-clostridium-tetani-and-clostridium-sporogenes
#3
E A Morozova, N V Anufrieva, D Zh Davydov, M V Komarova, I N Dyakov, A N Rodionov, T V Demidkina, V S Pokrovsky
PK studies were carried out after a single i.v. administration of 500 and 1000 U/kg by measuring of MGL activity in plasma samples. L-methionine concentration was measured by mass spectrometry. After single i.v. injection of 500U/kg the circulating T1/2 of enzymes in mice varies from 73 to 123min. The AUC0-tinf values determined for MGL 500U/kg from C. freundii, C. tetani and C. sporogenes are 8.21±0.28, 9.04±0.33 and 13.88±0.39U/(ml×h), respectively. Comparison of PK parameters of three MGL sources in the dose of 500U/kg indicated the MGL C...
February 5, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28144590/effects-of-hesperidin-as-a-radio-protector-on-apoptosis-in-rat-peripheral-blood-lymphocytes-after-gamma-radiation
#4
R Fardid, Zh Ghorbani, Gh Haddadi, A Behzad-Behbahani, R Arabsolghar, E Kazemi, M A Okhovat, S J Hosseinimehr
INTRODUCTION: Hesperidin (HES), as the most abundant flavonoid existing in the citrus, is widely used by human daily. The radio-protective effects of Hesperidin have been confirmed in various measurement systems. This study aimed to evaluate the effects of Hesperidin on the changes in the apoptosis level and expression of apoptotic genes target (bax, bcl-2 and ration of bax/bcl-2) in the peripheral blood lymphocytes of male rats after gamma radiation. MATERIALS AND METHODS: 64 male rats were divided into eight groups: Control, HES (100 mg/kg b...
December 2016: Journal of Biomedical Physics & Engineering
https://www.readbyqxmd.com/read/28105932/genes-of-susceptibility-to-early-neurodegenerative-changes-in-the-rat-retina-and-brain-analysis-by-means-of-congenic-strains
#5
Elena E Korbolina, Anna A Zhdankina, Anzhela Zh Fursova, Oyuna S Kozhevnikova, Natalia G Kolosova
BACKGROUND: There has been considerable interest in discovery of the genetic architecture of complex traits, particularly age-related neurodegenerative disorders. To predict disease risk and to understand its genetic basis in humans, it is necessary to study animal models. Our previous research on the accelerated-senescence OXYS strain has revealed two quantitative trait loci (QTLs) on rat chromosome 1 that are associated with early cataract and/or retinopathy as well as with behavioral abnormalities...
December 22, 2016: BMC Genetics
https://www.readbyqxmd.com/read/28058682/mi-1-gene-expression-in-tomato-plants-under-root-knot-nematode-invasion-and-treatment-with-salicylic-acid
#6
V V Lavrova, Zh V Udalova, E M Matveeva, F K Khasanov, S V Zinovieva
The dynamics of expression of two homologous genes Mi-1.1 and Mi-1.2 in the roots of resistant and susceptible tomato plants in non-invasion conditions and during invasion with the root-knot nematode M. incognita was studied. Nematode invasion was accompanied by a significant increase in the expression level of both genes; however, the accumulation of transcripts at the early stages of nematode invasion in the penetration of nematode juveniles to the roots was observed only in plants that contained the Mi-1...
November 2016: Doklady. Biochemistry and Biophysics
https://www.readbyqxmd.com/read/28057654/protocol-for-a-prospective-controlled-observational-study-to-evaluate-the-influence-of-hypoxia-on-healthy-volunteers-and-patients-with-inflammatory-bowel-disease-the-altitude-ibd-study
#7
Stephan Vavricka, Pedro A Ruiz, Sylvie Scharl, Luc Biedermann, Michael Scharl, Cheryl de Vallière, Carsten Lundby, Roland H Wenger, Leonhard Held, Tobias M Merz, Max Gassmann, Thomas Lutz, Andres Kunz, Denis Bron, Adriano Fontana, Laura Strauss, Achim Weber, Michael Fried, Gerhard Rogler, Jonas Zeitz
INTRODUCTION: Inflammatory bowel disease (IBD) is a chronic intestinal disorder, often leading to an impaired quality of life in affected patients. The importance of environmental factors in the pathogenesis of IBD, including their disease-modifying potential, is increasingly recognised. Hypoxia seems to be an important driver of inflammation, as has been reported by our group and others. The aim of the study is to evaluate if hypoxia can alter disease activity of IBD measured by Harvey-Bradshaw Activity Index in Crohn's disease (increase to ≥5 points) and the partial Mayo Score for ulcerative colitis (increase to ≥2 points)...
January 5, 2017: BMJ Open
https://www.readbyqxmd.com/read/28027545/social-and-psychological-state-of-the-chornobyl-clean-up-workers-risk-factors-for-negative-changes
#8
V O Buzunov, K N Loganovsky, L I Krasnikova, M O Bomko, Yu M Belyaev, Zh S Yaroshenko, T Ye Domashevska
: It is generally recognized that the Chornobyl nuclear accident caused strong psychosocial stress affecting the entire population of Ukraine, primarily people involved in recovery operations. But what are the reasons? What is the struc ture of stressors? What are their social, medical and biological consequences, what are strategy and preventive meas ures? Issues that require special research and development. OBJECTIVE: To study social and psychological state of the Chornobyl cleanup workers 1986-1987, and to determine regularities of changes and dangerous risk factors...
December 2016: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://www.readbyqxmd.com/read/27898856/the-effect-of-zilpaterol-hydrochloride-supplementation-on-energy-metabolism-and-nitrogen-and-carbon-retention-of-steers-fed-at-maintenance-and-fasting-intake-levels
#9
L J Walter, N A Cole, J S Jennings, J P Hutcheson, B E Meyer, A N Schmitz, D D Reed, T E Lawrence
An indirect calorimetry trial examined energy metabolism, apparent nutrient digestibility, C retention (CR), and N retention (NR) of cattle supplemented with zilpaterol hydrochloride (ZH). Beef steers ( = 20; 463 ± 14 kg) blocked ( = 5) by weight and source were individually fed and adapted to maintenance energy intake for 21 d before allotment to ZH (90 mg/steer∙d) or no β-adrenergic agonist treatment (control [CONT]) for 20 d (455 ± 14 kg at the start of treatment). Respiration chambers = 4 were used to quantify heat production (HP) during maintenance (d 12 to 16 of the ZH period) and fasting heat production (FHP; d 19 to 20 of ZH period; total 4 d of fast)...
October 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27878492/collagen-1-membrane-for-replacing-the-bladder-wall
#10
V I Kirpatovskii, A Yu Efimenko, V Yu Sysoeva, I S Mudraya, D M Kamalov, Zh A Akopyan, A A Kamalov
We studied the possibility of using membrane fabricated from type 1 collagen isolated from cattle tissues (group 1) or porcine tissues (group 2) for replacement of the resected bladder wall defect in rabbits in order to retain functional volume of the organ. Satisfactory take of both types of collagen membranes with formation of competent anastomosis was observed. Histological studies revealed inflammatory process in the bladder wall at the site of contact with the implanted membrane (more pronounced in case of membranes from cattle tissues) that decreased by day 21 of the experiment...
November 2016: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/27862329/exome-sequencing-identifies-fatp1-mutation-in-melkersson-rosenthal-syndrome
#11
LETTER
X G Xu, L P Guan, Y Lv, Y S Wan, Y Wu, R Q Qi, Zh G Liu, J G Zhang, Y L Chen, F P Xu, X Xu, Y H Li, L Geng, X H Gao, H D Chen
No abstract text is available yet for this article.
November 11, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27835013/analyzing-the-cp-nature-of-a-new-scalar-particle-via-s%C3%A2-zh-decays
#12
Martin Bauer, Matthias Neubert, Andrea Thamm
Scalar particles S that are singlets under the standard model gauge group are generic features of many models of fundamental physics, in particular, as possible mediators to a hidden sector. We show that the decay S→Zh provides a powerful probe of the CP nature of the scalar, because it is allowed only if S has CP-odd interactions. We perform a model-independent analysis of this decay using an effective Lagrangian and compute the relevant Wilson coefficients arising from integrating out heavy fermions to one-loop order...
October 28, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27801419/-ovarian-reserve-and-adipokine-levels-in-reproductive-aged-obese-women
#13
A K Durmanova, N K Otarbaev, A Kaiyrlykyzy, K Kh Zhangazieva, Zh N Ibraeva, G B Donenbaeva, Zh T Zhusupova, A S Saidakhmetov, G Sh Temirgalieva, Zh K Salykbaeva, Zh M Tazhigulova, A M Ensebaeva, K K Seksembaeva, O K Vasilenko, S Timanova, B Akkozhina
AIM: To investigate the relationship of the ovarian reserve to the levels of adipokines and sex hormones in reproductive-aged women with abdominal obesity. SUBJECTS AND METHODS: A total of 157 women aged 18 to 45 years with a body mass index (BMI) of more than 30 kg/m2 were examined (a study group). A control group consisted of 93 women aged 18-45 years with a BMI of less than 25 kg/m2. Anthropometric and carbohydrate and lipid metabolic parameters and the levels of sex hormones, anti-Müllerian hormone, resistin, and adiponectin were investigated...
2016: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/27636763/clinical-microbiological-research-of-action-ozone-therapy-and-light-emetting-diode-radiation-of-red-range-630-nanometers-on-microflora-of-the-hole-extracted-toothatalveolitis-and-limited-osteomyelitis-of-jaws
#14
Yu I Chergeshtov, V N Tsarev, A G Volkov, A S Nosik, N Zh Dikopova, D A Malanchuk
As a result of cliniko-microbiological research the data testifying to substantial improvement of efficiency of antimicrobictherape at inclusion in a complex of medical actions at alveolitis and the limited osteomyelitis of a jow ozone therapy in a combination with a light-emettinf diode irradiation of the hole extracted teeth red ( 630 nanometers) are obtained by light.
2016: Stomatologii︠a︡
https://www.readbyqxmd.com/read/27600893/-effectiveness-of-diffuse-diabetic-macular-edema-treatment-in-relation-to-structural-changes-in-macular-region
#15
A Zh Fursova, N V Chubar', M S Tarasov, I F Saifullina, G G Pustovaya
AIM: to describe baseline functional and anatomical parameters of the macular region and how they change under ranibizumab therapy depending on the type of diabetic macular edema (DME) determined with optical coherence tomography (OCT). MATERIAL AND METHODS: The study included 100 patients (100 eyes) with diabetes mellitus and DME (38 men and 62 women) aged 61.9±5.6 years with the mean disease duration of 8.48 years. Basing on OCT findings, 4 groups (25 patients each) were formed: sponge-like DME, cystoid DME, DME with serous neuroepithelium detachment (NED), and mixed DME (cystoid DME and serous NED)...
July 2016: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/27600777/-clinical-immunohistochemical-and-molecular-genetic-prognostic-factors-in-adult-patients-with-glioblastoma
#16
N V Lobanova, L V Shishkina, M V Ryzhova, G L Kobyakov, R V Sycheva, S A Burov, A V Luk'yanov, Zh R Omarova
UNLABELLED: Glioblastoma is the most common primary malignant glial tumor of the brain in adult patients. AIM: to define the prognostic value of isocitrate dehydrogenase-1 (IDH-1) mutation and methylguanine-DNA methyltransferase (MGMT) methylation status in patients with glioblastoma (GB) and to analyze the impact of clinical data (gender, age, and tumor site), histological variants of the tumor structure, and time to development of recurrences on the course of the disease...
July 2016: Arkhiv Patologii
https://www.readbyqxmd.com/read/27562997/-thiol-peroxidase-activities-in-rat-blood-plasma-determined-with-hydrogen-peroxide-and-5-5-dithio-bis-2-nitrobenzoic-acid
#17
A V Razygraev, K I Taborskaya, M A Petrosyan, Zh N Tumasova
Earlier it has been shown that extracellular glutathione peroxidase (GPx3) from human plasma is able to use cysteine (Cys-SH) instead of glutathione (GSH) as a thiol substrate. In the present study, the ability of rat plasma to utilize not only GSH, but also Cys-SH and homocysteine (Hcy-SH), in the thiol peroxidase reaction has been confirmed. The molar ratio between thiol and H2O2 in the catalyzed reaction was 2:1. The specific activity increased with fractionation of proteins. At a fixed thiol concentration of 0...
May 2016: Biomedit︠s︡inskai︠a︡ Khimii︠a︡
https://www.readbyqxmd.com/read/27522727/-evaluation-of-arterial-stiffness-and-possibility-to-predict-carotid-atherosclerosis-in-patients-with-essential-hypertension-based-on-an-outpatient-facility
#18
A G Polipanov, Zh A Mamasaidov, Yu N Geleskhanova, N B Cheskidova, T A Romanova, A S Dzhumagulova
AIM: To estimate the possibility of predicting the presence and severity of coronary atherosclerosis from arterial stiffness characteristics and augmentation index (AIx) in patients with essential hypertension (EH) obtained under outpatient conditions. MATERIALS AND METHODS: The general clinical examination of 15 patients aged 30-70 yr with EH was supplemented by measuring blood glucose and creatinine levels, the lipid status (LWLP, HDLP, TG), duplex scanning of carotid arteries, and evaluation of arterial stiffness by pulsed wave contour analysis...
2016: Klinicheskaia Meditsina
https://www.readbyqxmd.com/read/27496028/antiproliferative-effects-of-modified-bioflavonoid-in-ex-vivo-model
#19
D Z Albegova, O V Kamkina, S I Pavlova, Zh K Albegova, O S Laptev, I G Kozlov
We studied the effect of modified bioflavonoid and reference drug quercetin dihydrate on proliferation of mononuclears triggered by T- and B-cell mitogens. Lymphocytes were in vivo pretreated with the examined agents followed by their explantation and in vitro activation with T- and B-cell mitogens in cell culture. Intraperitoneal injection of modified bioflavonoid and quercetin dihydrate produced a dose-dependent inhibition of proliferation of the in vitroactivated splenocytes; modified bioflavonoid demonstrated higher antiproliferative activity...
July 2016: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/27466007/the-influence-of-changes-in-expression-of-redox-sensitive-genes-on-the-development-of-retinopathy-in-rats
#20
M L Perepechaeva, N G Kolosova, N A Stefanova, A Zh Fursova, A Y Grishanova
Age-related macular degeneration (AMD) is a complex multifactorial disease of the elderly, with unclear pathogenesis; AMD is the leading cause of blindness. One of the destructive processes in AMD is oxidative stress, which leads to an imbalance in the processes responsible for production and detoxification of reactive oxygen species. The aryl hydrocarbon receptor (AhR) signaling pathway can participate in the development of oxidative stress, but the main regulator of antioxidant defense is nuclear factor, erythroid derived 2 (Nrf2)...
August 2016: Experimental and Molecular Pathology
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