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Macrosomia

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https://www.readbyqxmd.com/read/29158542/metabolic-profiling-of-umbilical-cord-blood-in-macrosomia
#1
H Sun, Y Wang, C Wang, X Xu, Y Wang, H Yan, X Yang
BACKGROUND/OBJECTIVE: The term macrosomia is used to describe neonates with a birth weight of 4000 g or more. Macrosomia is a potential risk factor for obesity and metabolic syndromes in postnatal and adult life, yet little is known about its associations with metabolic difference in the early-age. We performed metabolic profiling of umbilical cord blood to discover differential metabolites of macrosomia. METHODS: We conducted a case-control study of full-term singletons with normal maternal glucose tolerance [50 cases (macrosomia, birth weight ⩾4000 g); 50 controls (normal weight, birth weight 2500-3999 g)]...
November 21, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29157030/one-step-versus-two-step-approach-for-gestational-diabetes-screening-systematic-review-and-meta-analysis-of-the-randomized-trials
#2
Gabriele Saccone, Claudia Caissutti, M D Adeeb Khalifeh, Sara Meltzer, M D Christina Scifres, Hyagriv N Simhan, Sefa Kelekci, Sevket M D Osman, Vincenzo Berghella
INTRODUCTION: To compare both the prevalence of gestational diabetes mellitus (GDM) as well as maternal and neonatal outcomes by either the one-step or the two-step approaches. MATERIAL AND METHODS: Electronic databases were searched from their inception until June 2017. We included all randomized controlled trials (RCTs) comparing the one-step with the two-step approaches for the screening and diagnosis of GDM. The primary outcome was the incidence of GDM. RESULTS: Three RCTs (n = 2333 participants) were included in the meta-analysis...
November 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29141697/microarray-expression-profile-of-lncrnas-and-mrnas-in-the-placenta-of-non-diabetic-macrosomia
#3
G Y Song, Q Na, D Wang, C Qiao
Macrosomia, not only is closely associated with short-term, birth-related problems, but also has long-term consequences for the offspring. We investigated the expression of long non-coding RNAs (lncRNAs) and messenger RNAs (mRNAs) in the placenta of macrosomia births using a microarray profile. The data showed that 2929 lncRNAs and 4574 mRNAs were upregulated in the placenta of macrosomia births compared with the normal birth weight group (fold change ⩾2.0, P<0.05), and 2127 lncRNAs and 2511 mRNAs were downregulated (fold change ⩾2...
November 16, 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/29137266/correlation-of-placental-microbiota-with-fetal-macrosomia-and-clinical-characteristics-in-mothers-and-newborns
#4
Jia Zheng, Xin-Hua Xiao, Qian Zhang, Li-Li Mao, Miao Yu, Jian-Ping Xu, Tong Wang
Substantial studies indicated that fetal macrosomia was associated with detrimental pregnancy outcomes, and increased susceptibility to metabolic diseases in later life. However, investigations into the association between placental microbiota and fetal macrosomia are limited. We aimed to profile the placental microbiota of fetal macrosomia and study whether they relate to clinical characteristics. Placenta samples were collected from fetal macrosomias and newborns with normal birth weight. The clinical characteristics, umbilical cord blood parameters were measured, and placental microbiota were sequenced and further analysed...
October 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29121896/pre-pregnancy-body-mass-index-and-gestational-weight-gain-and-their-effects-on-pregnancy-and-birth-outcomes-a-cohort-study-in-west-sumatra-indonesia
#5
Hora Soltani, Nur I Lipoeto, Frankie J Fair, Karen Kilner, Y Yusrawati
BACKGROUND: Indonesia has a considerably high incidence of maternal and infant mortality. The country has however been experiencing a social and economic transition, influencing its general population demographics and nutritional status including the state of health and nutrition of pregnant women. This study aimed to explore body mass index (BMI) and gestational weight gain (GWG), and their relationship with pregnancy outcomes in a sample of Indonesian pregnant women. METHODS: This observational cohort study included a total of 607 pregnant women who were recruited in 2010 from maternity clinics in Western Sumatra, Indonesia...
November 9, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/29103236/new-israeli-sonographic-estimated-fetal-weight-growth-curves-as-compared-to-current-birth-weight-growth-curves-on-what-should-diagnosis-of-intrauterine-growth-disorders-be-based
#6
Alon Z Sapir, Izzat Khayyat, Ron Rabinowitz, Arnon Samueloff, Lior Drukker, Hen Y Sela
BACKGROUND: Two types of growth curves are commonly used to diagnose fetal growth disorders: neonatal birth weight (BW) and sonographic estimated fetal weight (EFW). The debate as to which growth curve to use is universal. OBJECTIVES: To establish sonographic EFW growth curves for the Israeli population and to assess whether the use of the BW growth curves currently adapted in Israel leads to under-diagnosis of intrauterine growth disorders. METHODS: Biometric data collected during a 6 year period was analyzed to establish sonographic EFW growth curves between 15-42 weeks of gestation for the Israeli population...
October 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29091257/are-women-positive-for-the-one-step-but-negative-for-the-two-step-screening-tests-for-gestational-diabetes-at-higher-risk-for-adverse-outcomes
#7
Claudia Caissutti, Adeeb Khalifeh, Gabriele Saccone, Vincenzo Berghella
INTRODUCTION: To evaluate if women meeting criteria for gestational diabetes mellitus (GDM) by the One Step test as per International Association of the Diabetes and Pregnancy Study Groups (IADPSG) criteria but not by other less strict criteria have adverse pregnancy outcomes compared to GDM negative controls. The primary outcome was the incidence of macrosomia, defined as birth weight >4,000 grams. MATERIAL AND METHODS: Electronic databases were searched from their inception until May 2017...
November 1, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29083138/an-early-customized-low-glycaemic-index-diet-prevents-adverse-pregnancy-outcomes-in-overweight-obese-women
#8
Elisabetta Petrella, Valeria Tamborrino, Lidia DI Cerbo, Isabella Neri, Fabio Facchinetti
OBJECTIVE: To determine whether the prescription and follow-up of a behavioral program (customized nutritional advices and a constant physical activity) influences the occurrence of unfavorable maternal/neonatal outcomes among overweight/obese women. METHODS: A case-control study (1:3) included single pregnant women with BMI≥25, enrolled at 1st trimester. Cases (95) were prescribed (by both the dietitian and gynecologist) a low-glycemic index diet with an average intake of 1700/1800 Kcal/day plus 30 minutes walking at least 3 times/week (with four follow-up visits until delivery)...
October 27, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/29080962/maternal-pre-pregnancy-obesity-and-the-risk-of-macrosomia-a-meta-analysis
#9
Rui-Xue Dai, Xiu-Jie He, Chuan-Lai Hu
PURPOSE: The aim of our meta-analysis was to explore whether pre-pregnancy obesity is regarded as an important risk factor for predicting macrosomia or not. METHODS: Three databases were systematically reviewed and reference lists of relevant articles were checked. Meta-analysis of published cohort studies comparing whether pre-pregnancy obesity was associated with macrosomia and adjusting for potential confounding factors. Calculations of pooled estimates were conducted in random-effect model...
October 28, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29074629/obesity-and-gynaecological-and-obstetric-conditions-umbrella-review-of-the-literature
#10
REVIEW
Ilkka Kalliala, Georgios Markozannes, Marc J Gunter, Evangelos Paraskevaidis, Hani Gabra, Anita Mitra, Vasso Terzidou, Phillip Bennett, Pierre Martin-Hirsch, Konstantinos K Tsilidis, Maria Kyrgiou
Objective To study the strength and validity of associations between adiposity and risk of any type of obstetric or gynaecological conditions.Design An umbrella review of meta-analyses.Data sources PubMed, Cochrane database of systematic reviews, manual screening of references for systematic reviews or meta-analyses of observational and interventional studies evaluating the association between adiposity and risk of any obstetrical or gynaecological outcome.Main outcomes Meta-analyses of cohort studies on associations between indices of adiposity and obstetric and gynaecological outcomes...
October 26, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29056269/prevalence-of-low-birthweight-and-macrosomia-in-a-private-clinic-in-north-mexico
#11
Héctor Eloy Tamez-Pérez, Lucas Antonio Garza-Garza, Mayra Hernández Coria, Alejandra Lorena Tamez-Peña, Juan Manuel Escobedo-Lobatón
No abstract text is available yet for this article.
October 2017: Endocrinología, diabetes y nutrición
https://www.readbyqxmd.com/read/29037224/maternal-and-fetal-blood-lipid-concentrations-during-pregnancy-differ-by-maternal-body-mass-index-findings-from-the-rolo-study
#12
Aisling A Geraghty, Goiuri Alberdi, Elizabeth J O'Sullivan, Eileen C O'Brien, Brenda Crosbie, Patrick J Twomey, Fionnuala M McAuliffe
BACKGROUND: Pregnancy is a time of altered metabolic functioning and maternal blood lipid profiles change to accommodate the developing fetus. While these changes are physiologically necessary, blood lipids concentrations have been associated with adverse pregnancy outcomes such as gestational diabetes, pregnancy-induced hypertension and high birth weight. As blood lipids are not routinely measured during pregnancy, there is limited information on what is considered normal during pregnancy and in fetal blood...
October 16, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29026373/how-weight-during-pregnancy-influences-the-association-between-pre-pregnancy-body-mass-index-and-types-of-delivery-and-birth-a-comparison-of-urban-and-rural-areas
#13
Manoochehr Babanezhad
BACKGROUND: Women in study areas suffered from the problems of caesarean delivery (CD), low birth weight (LBW), and macrosomia. OBJECTIVE: To investigate how gestational weight gain (GWG) influences the effect of the pre-pregnancy body mass index (BMI) on the risks of CD, LBW, and macrosomia in urban and rural areas in a city of Iran. METHODS: We used 767 and 612 eligible subjects from the public health care centers in urban and rural areas respectively...
March 2017: African Health Sciences
https://www.readbyqxmd.com/read/28988808/impact-of-new-international-association-of-diabetes-and-pregnancy-study-groups-iadpsg-diagnostic-criteria-on-perinatal-outcomes-in-a-regional-tertiary-hospital-in-new-south-wales-australia
#14
Hong Lin Evelyn Tan, Judy Luu, Amanda Caswell, Elizabeth Holliday, John Attia, Shamasunder Acharya
AIMS: We compared the impact of new gestational diabetes (GDM) diagnostic criteria by IADPSG with previous criteria to ascertain concordance between the two criteria; and whether women discordant for GDM between the old and new criteria had increased pregnancy complications. METHODS: Oral glucose tolerance tests of pregnant women across time periods using old criteria and new criteria were collected. Maternal data and perinatal outcomes were compared between diagnostic concordant and discordant women...
October 6, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28977845/quantitative-assessment-of-the-effect-of-pre-gestational-diabetes-and-risk-of-adverse-maternal-perinatal-and-neonatal-outcomes
#15
Lei Yu, Xiao-Ling Zeng, Ming-Liang Cheng, Guo-Zhen Yang, Bi Wang, Zi-Wen Xiao, Xin Luo, Bao-Fang Zhang, De-Wei Xiao, Shuai Zhang, Hua-Juan Liu, Ya-Xin Hu, Hou-Kang Lei, Qin-Fen Li, Zheng-Rong Wang
Pregnancies complicated by pre-gestational diabetes (PGD) are associated with a higher rate of adverse outcomes, including an increased rage of preterm delivery, pregnancy-induced hypertension, pre-eclampsia, caesarean section, perinatal mortality, stillbirth, shoulder dystocia, macrosomia, small for gestational age, large for gestational age, low birth weight, neonatal hypoglycemia, neonatal death, low Apgar score, NICU admission, jaundice and respiratory distress. In the past two decades, numerous reports have been published regarding associations between PGD and risk of adverse outcomes...
September 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28970543/relationship-between-gestational-weight-gain-and-pregnancy-complications-or-delivery-outcome
#16
Wenjia Yang, Feifei Han, Xueying Gao, Yifei Chen, Linong Ji, Xiaoling Cai
The purpose of this study is to analyse the association between gestational weight gain and delivery outcome or the morbidity of pregnancy complications. A total of 1,102 pregnant women who delivered at Peking University People's Hospital in China between January 2011 and December 2012 were included in this study. We divided them into 4 groups according to the baseline BMI quartiles and weight gain quartiles in different trimesters of pregnancy to analyse the status of delivery outcome and morbidity of pregnancy complications...
October 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28949002/effect-of-individual-dietetic-intervention-on-gestational-weight-gain-and-associated-complications-in-obese-pregnant-women
#17
Nicole Robertson, Bridget Ladlow
BACKGROUND: Maternal obesity and excessive gestational weight gain (GWG) are prevalent in Australia and associated with an increased risk of birth complications, gestational diabetes and caesarean delivery. AIM: To assess the effect of a pilot dietetic intervention in supporting the achievement of appropriate GWG. MATERIALS AND METHODS: Pregnant women with a pre-pregnancy body mass index (BMI) ≥ 35 kg/m(2) (n = 174, mean BMI 40.6 ± 4...
September 26, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28947460/birth-outcomes-of-immigrant-women-married-to-native-men-in-the-republic-of-korea-a-population-register-based-study
#18
In Gyu Song, Min Sun Kim, Seung Han Shin, Ee-Kyung Kim, Han-Suk Kim, Seulggie Choi, Soonman Kwon, Sang Min Park
OBJECTIVES: The Republic of Korea (Korea) has experienced a steady increase in the number of births from immigrant women over the last 20 years. However, little is known about the birth outcomes of immigrant women in Korea. This study compared Korean birth data from immigrant and native women who married native men, and explored the factors that affected birth outcomes among immigrant women. DESIGN: Observational cross-sectional study. SETTING: Nationwide registry-based study in Korea...
September 24, 2017: BMJ Open
https://www.readbyqxmd.com/read/28942514/intrauterine-hyperglycemia-induced-inflammatory-signalling-via-the-receptor-for-advanced-glycation-end-products-in-the-cardiac-muscle-of-the-infants-of-diabetic-mother-rats
#19
Ritsuko Kawaharada, Haruna Masuda, Zhenyi Chen, Eric Blough, Tomoko Kohama, Akio Nakamura
PURPOSE: Gestational diabetes is associated with increased risk to the health of the mother and her offspring. In particular, the infants of diabetic mothers (IDMs) exhibit elevated levels of preterm birth, macrosomia, hypoglycemia, hypocalcemia, and cardiomyopathy. We have previously reported that IDMs showed abnormalities in cardiac Akt-related insulin signalling, and that these deficiencies in Akt-related signalling were attenuated by supplementing the maternal diet with fish-oil. Herein, we investigated whether the eicosapentaenoic acid (EPA) found in fish oil can be used to attenuate diabetes associated impairments in cardiomyocyte signalling...
September 23, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28935485/erratum-to-craniofacial-and-extracraniofacial-anomalies-in-craniofacial-macrosomia-a-multicenter-study-of-755-patients-j-craniomaxillofac%C3%A2-surg-vol-45-8-august-2017-1302-1310
#20
Cornelia J J M Caron, Britt I Pluijmers, Eppo B Wolvius, Caspar W N Looman, Neil Bulstrode, Robert D Evans, Peter Ayliffe, John B Mulliken, David Dunaway, Bonnie Padwa, Maarten J Koudstaal
No abstract text is available yet for this article.
September 18, 2017: Journal of Cranio-maxillo-facial Surgery
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