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https://www.readbyqxmd.com/read/29323444/impact-of-new-diagnostic-criteria-for-gestational-diabetes
#1
Holly Sexton, Clare Heal, Jennifer Banks, Kathleen Braniff
AIM: In January 2015, the diagnostic and therapeutic criteria for gestational diabetes changed, with the goal of increasing the sensitivity of diagnosis and improving overall glycemic control, and thus reducing adverse pregnancy outcomes. Our primary aim was to evaluate the effect of the new guidelines on the incidence of diagnosis of gestational diabetes and the incidence of therapeutic interventions. Our secondary aim was to look at the incidence of adverse pregnancy outcomes. METHODS: A retrospective clinical audit was conducted at a regional hospital to compare the incidence of gestational diabetes, and the specific maternal and neonatal outcomes before and after the change in guidelines was implemented...
January 11, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29319918/comparison-of-modified-two-point-dixon-and-chemical-shift-encoded-mri-water-fat-separation-methods-for-fetal-fat-quantification
#2
Stephanie A Giza, Michael R Miller, Prasiddha Parthasarathy, Barbra de Vrijer, Charles A McKenzie
BACKGROUND: Fetal fat is indicative of the energy balance within the fetus, which may be disrupted in pregnancy complications such as fetal growth restriction, macrosomia, and gestational diabetes. Water-fat separated MRI is a technique sensitive to tissue lipid content, measured as fat fraction (FF), and can be used to accurately measure fat volumes. Modified two-point Dixon and chemical shift encoded MRI (CSE-MRI) are water-fat separated MRI techniques that could be applied to imaging of fetal fat...
January 10, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29316857/changes-in-serum-lipid-levels-during-pregnancy-and-association-with-neonatal-outcomes-a-large-cohort-study
#3
Wei Zheng, Wenyu Huang, Li Zhang, Zhihong Tian, Teng Wang, Ting Zhang, Zhi Zhang, Weiyuan Zhang, Guanghui Li
BACKGROUND: This study is aimed to characterize changes in serum lipid levels throughout pregnancy and explore the association between lipid levels and neonatal outcomes. METHODS: This study included singleton pregnancy women who received regular prenatal care and delivered at Beijing Obstetrics and Gynecology Hospital from January 2014 to December 2014. Baseline information and neonatal outcomes were collected from medical record review. Serum lipid levels in the first trimester (7-13 weeks) and third trimester (>32 weeks) were measured...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29303230/planned-birth-at-or-near-term-for-improving-health-outcomes-for-pregnant-women-with-gestational-diabetes-and-their-infants
#4
REVIEW
Linda M Biesty, Aoife M Egan, Fidelma Dunne, Eugene Dempsey, Pauline Meskell, Valerie Smith, G Meabh Ni Bhuinneain, Declan Devane
BACKGROUND: Gestational diabetes is a type of diabetes that occurs during pregnancy. Women with gestational diabetes are more likely to experience adverse health outcomes such as pre-eclampsia or polyhydramnios (excess amniotic fluid). Their babies are also more likely to have health complications such as macrosomia (birthweight > 4000 g) and being large-for-gestational age (birthweight above the 90th percentile for gestational age). Current clinical guidelines support elective birth, at or near term in women with gestational diabetes to minimise perinatal complications, especially those related to macrosomia...
January 5, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29301466/immediate-perinatal-outcomes-of-postterm-deliveries
#5
Or Maoz, Tamar Wainstock, Eyal Sheiner, Asnat Walfisch
OBJECTIVE: To investigate whether postterm pregnancy (≥42 0/7 weeks' gestation) increases the risk for adverse perinatal outcome. STUDY DESIGN: In this population based cohort study, all singleton deliveries occurring between 1991 and 2014 in a tertiary medical center were included. Pregnancy and perinatal outcomes were compared between postterm and term deliveries (37 0/7 to 41 6/7 weeks' gestation). Preterm deliveries, unknown gestational age, congenital malformations, and multiple gestations, were excluded...
January 4, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29294574/-outcomes-of-pregnancy-among-women-with-alpha-thalassemia-minor-a-retrospective-study-of-pingguo-county-in-guangxi-zhuang-autonomous-region
#6
T Pang, X F Guo, Y H Zhou, X Q Qiu, S Li, Z R Liang, X L Qin, K H Li, X Y Zeng
Objective: To investigate the association between the value of α-thalassemia minor and the outcomes in pregnant women. Methods: A total of 445 pregnant women with α-thalassemia minor were selected as thalassemia group in the Pingguo County Maternal and Child Health Hospital of Guangxi from January 2011 to December 2015, with ratio of 1∶4 healthy pregnant women was randomly recruited as non-thalassemia group. Clinical characteristics and pregnancy outcomes of the two groups were retrospectively analyzed using methods including t test, χ(2) test, and logistic regression model and ROC curve...
December 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/29291410/effect-of-frozen-thawed-embryo-transfer-on-birthweight-macrosomia-and-low-birthweight-rates-in-us-singleton-infants
#7
Julia F Litzky, Sheree L Boulet, Navid Esfandiari, Yujia Zhang, Dmitry M Kissin, Regan N Theiler, Carmen J Marsit
BACKGROUND: Singleton infants conceived using assisted reproductive technology have lower average birthweights than naturally-conceived infants and are more likely to be born low birthweight (<2500 grams). Lower birthweights are associated with increased infant and child mortality and poor adult health outcomes, including cardiovascular disease, hypertension, and diabetes. Data from registry and single center studies suggest that frozen/thawed embryo transfer may be associated with larger birthweights...
December 29, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29285448/maternal-and-neonatal-outcome-in-mothers-with-gestational-diabetes-mellitus
#8
G Thiruvikrama Prakash, Ashok Kumar Das, Syed Habeebullah, Vishnu Bhat, Suryanarayana Bettadpura Shamanna
Introduction: Gestational diabetes mellitus (GDM) is common and is accompanied with other comorbidities. Challenges to treatment exist at our institute as it serves women with low income. This study assessed the burden of comorbidities and the outcome of GDM. Methods: This was a prospective, observational study of women with gestational diabetes attending the obstetrics department from September 2012 to April 2014. GDM was diagnosed based on the International Association of Diabetes and Pregnancy Study Groups criteria...
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29279948/developmental-patterns-of-fetal-fat-and-corresponding-signal-on-t1-weighted-magnetic-resonance-imaging
#9
Eléonore Blondiaux, Lydia Chougar, Antoinette Gelot, Stéphanie Valence, Etienne Audureau, Hubert Ducou le Pointe, Jean-Marie Jouannic, Ferdinand Dhombres, Catherine Garel
BACKGROUND: Evaluation of subcutaneous fetal fat layer thickness on T1-weighted sequences can be used to predict birth weight. Little is known about normal MR signal patterns of subcutaneous tissue throughout pregnancy. OBJECTIVE: To establish developmental patterns of subcutaneous fetal fat signal on T1-weighted sequences during the 2nd and 3rd trimesters. MATERIALS AND METHODS: We retrospectively examined T1-weighted images of 110 fetal MRI scans...
December 26, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/29278829/efficacy-of-maternal-and-biological-parameters-at-the-time-of-diagnosis-of-gestational-diabetes-mellitus-in-predicting-neonatal-morbidity
#10
Guillaume Ducarme, François Desroys Du Roure, Aurélie Le Thuaut, Joséphine Grange, Jérôme Dimet, Ingrid Crepin-Delcourt
OBJECTIVE: Gestational diabetes mellitus (GDM) is independently associated with an increased risk of maternal-fetal complications. Improved glycemic control allows reducing perinatal morbidity and mortality and, specifically, the risk of macrosomia and shoulder dystocia which are the most common complications associated with GDM. Nonetheless, a need for early antenatal predictor of neonatal morbidity in women suffering from GDM is required. The objective of the study was to evaluate the efficacy of different maternal, biological, and antenatal parameters at the time of diagnosis of GDM or perinatal variables as predictors of neonatal morbidity...
December 19, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29278514/maternal-serum-placental-growth-hormone-insulin-like-growth-factors-and-their-binding-proteins-at-20-weeks-gestation-in-pregnancies-complicated-by-gestational-diabetes-mellitus
#11
Shutan Liao, Mark H Vickers, Rennae S Taylor, Mhoyra Fraser, Lesley M E McCowan, Philip N Baker, Jo K Perry
OBJECTIVE: To investigate whether maternal serum concentrations of placental growth hormone (GH-V), insulin-like growth factor (IGF) 1 and 2, and IGF binding proteins (IGFBP) 1 and 3 were altered in pregnancies complicated by gestational diabetes mellitus (GDM). METHOD: In a nested case-control study, GDM cases (n=28) and matched controls (n=28) were selected from the Screening for Pregnancy Endpoints (SCOPE) biobank in Auckland, New Zealand. Maternal serum hormone concentrations at 20 weeks of gestation were determined by enzyme-linked immunosorbent assay (ELISA)...
July 2017: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29196154/labour-induction-practices-in-france-a-population-based-declarative-survey-in-94-maternity-units
#12
P Blanc-Petitjean, M Salomé, C Dupont, C Crenn-Hebert, A Gaudineau, F Perrotte, P Raynal, E Clouqueur, G Beucher, B Carbonne, F Goffinet, C Le Ray
INTRODUCTION: In 2010, 22.7% of deliveries in France were induced. The current lack of high level of evidence data about the methods and indications for induction of labour has promoted heterogeneous and non-recommended practices. The extent of these different practices is not adequately known in France today, although they may influence perinatal outcomes. The objective of this study was to report current practices of induction of labour in France. MATERIAL AND METHODS: This study surveyed 94 maternity units in seven perinatal networks...
November 28, 2017: Journal of Gynecology Obstetrics and Human Reproduction
https://www.readbyqxmd.com/read/29187658/-pregnancy-complications-among-women-with-polycystic-ovary-syndrome-in-china-a-meta-analysis
#13
Tingting Wang, Hanlin Fu, Lizhang Chen, Yang Xu
To estimate the status of pregnancy complications among women with polycystic ovary syndrome (PCOS) through a systematic review of published literatures.
 Methods: Systematic literature searches were conducted in PubMed, Web of Science, Medline, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang, Weipu and China Biology Medicine disc (CBMdisc), as well as the relevant articles published from inception to April 1st 2017, which reported the prevalence of pregnancy complications among women with PCOS...
November 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/29183184/third-trimester-ultrasound-for-fetal-macrosomia-optimal-timing-and-institutional-specific-accuracy
#14
Laura I Parikh, Sara N Iqbal, Angie C Jelin, Rachael T Overcash, Eshetu Tefera, Melissa H Fries
PURPOSE: To determine the performance of third trimester ultrasound in women with suspected fetal macrosomia. MATERIALS AND METHODS: We performed a retrospective cohort study of fetal ultrasounds from January 2004 to December 2014 with estimated fetal weight (EFW) between 4000 and 5000 g. We determined accuracy of birth weight prediction for ultrasound performed at less than and greater than 38 weeks, accounting for diabetic status and time between ultrasound and delivery...
November 28, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29183096/morbidity-associated-with-fetal-macrosomia-among-women-with-diabetes-mellitus
#15
Zachary B Jenner, Amy E O'Neil Dudley, Hector Mendez-Figueroa, Viviana S Ellis, Han-Yang Chen, Suneet P Chauhan
No abstract text is available yet for this article.
November 28, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/29182561/analysis-of-microrna-expression-in-newborns-with-differential-birth-weight-using-newborn-screening-cards
#16
Patricia Rodil-Garcia, Elvira Del Carmen Arellanes-Licea, Angélica Montoya-Contreras, Luis A Salazar-Olivo
Birth weight is an early predictor for metabolic diseases and microRNAs (miRNAs) are proposed as fetal programming participants. To evaluate the use of dried blood spots (DBS) on newborn screening cards (NSC) as a source of analyzable miRNAs, we optimized a commercial protocol to recover total miRNA from normal birth weight (NBW, n = 17-20), low birth weight (LBW, n = 17-20) and high birth weight (macrosomia, n = 17-20) newborns and analyzed the relative expression of selected miRNAs by stem-loop RT-qPCR. The possible role of miRNAs on the fetal programming of metabolic diseases was explored by bioinformatic tools...
November 28, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29177963/the-associations-between-air-pollution-and-adverse-pregnancy-outcomes-in-china
#17
Yafei Tan, Rong Yang, Jinzhu Zhao, Zhongqiang Cao, Yawen Chen, Bin Zhang
Research on the potential impact of air pollution on the human's health has increased rapidly in recent years. Several studies have suggested that exposure to air pollutants during period of pregnancy which is a crucial time point of mother-fetus development may have long-term and serious impact on adverse pregnancy outcomes. There is lack of review to evaluate the existed epidemiologic evidence on the associations between air pollutants and adverse pregnancy outcomes in China, so we conducted a review to explore the current epidemiological evidence on the effects of air pollutants to pregnancy outcomes and possible mechanisms during the pregnancy process...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29172881/the-institute-of-medicine-recommendation-for-gestational-weight-gain-is-probably-not-optimal-among-non-american-pregnant-women-a-retrospective-study-from-china
#18
Xiang Jiang, Ming Liu, Yuehua Song, Jing Mao, Mulan Zhou, Zhenfang Ma, Xiaohu Qian, Zhimin Han, Tao Duan
PURPOSE: To investigate whether the Institute of Medicine (IOM) recommended gestational weight gain (GWG) range is optimal among Chinese singleton pregnant women. METHODS: For the purpose of a retrospective observational study, data on 8209 mature singleton deliveries in Shanghai from January 2014 to December 2016 were extracted from medical records in terms of clinical performance. All cases were categorized as undergainers, appropriate-gainers, and above-gainers according to IOM recommended gestational weight gain range after stratification of maternal BMI and proportions of three categories were calculated...
November 27, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29167502/effect-of-maternal-glycemia-and-weight-status-on-offspring-birth-measures-and-bmi-z-among-chinese-population-in-the-first-year
#19
Yilin Huang, Baoming Yin, Xiaohong Liang, Hong Mei, Hongyan Lu, Shuixian Xie, Weihong Bei, Wenhua Mei, Jianduan Zhang
To investigate the effects of maternal fasting plasma glucose (FPG) and pre-pregnancy weight status (PPWS) on offspring birth measures and body mass index z-score (BMI-z) in the first year, we conducted a prospective study of 1,096 mother-infant dyads in Guangdong, China, 2014-2015. Multivariate logistic regression was used to test independent/interaction associations of maternal FPG and PPWS with macrosomia/large for gestational age (LGA). Association of PPWS and FPG with offspring BMI-z in the first year was assessed by the linear mixed effects models...
November 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29167317/rodent-vertical-sleeve-gastrectomy-alters-maternal-immune-health-and-feto-placental-development
#20
Redin A Spann, Wiiliam J Lawson, Gene L Bidwell, C Austin Zamarripa, Rodrigo O Maranon, Sibali Bandyopadhyay, Erin R Taylor, Jane F Reckelhoff, Michael R Garrett, Bernadette E Grayson
Bariatric surgery is increasingly employed to improve fertility and reduce obesity related co-morbidities in obese women. Surgical weight loss not only improves the chance of conception but reduces the risk of pregnancy complications including pre-eclampsia, gestational diabetes, and macrosomia. However, bariatric procedures increase the incidence of intrauterine growth restriction (IUGR), fetal demise, thromboembolism and other gestational disorders. Using our rodent model of vertical sleeve gastrectomy (VSG), we tested the hypothesis that VSG in diet-induced, obese dams would cause immune and placental structural abnormalities that may be responsible for fetal demise during pregnancy...
November 22, 2017: Clinical Science (1979-)
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