keyword
MENU ▼
Read by QxMD icon Read
search

hima

keyword
https://www.readbyqxmd.com/read/28675346/trigeminal-neuralgia-caused-by-a-new-variant-of-persistent-trigeminal-artery-associated-with-agenesis-of-internal-carotid-artery
#1
Gorky Medhi, Hima Pendharkar, Karel terBrugge, Chandrajit Prasad, Arun Kumar Gupta
We report a hitherto undescribed persistent carotid vertebral anastomosis associated with ipsilateral internal carotid artery agenesis and bilateral duplication of the intradural vertebral arteries. This rare anomaly was detected on MRI, supplemented by CT angiography while evaluating for cause trigeminal neuralgia in a 37-year-old woman. The aberrant vessel was seen to cause thinning and lateral displacement of the left trigeminal nerve on CISS 3D images. Also noted was a bilateral vertebral artery duplication of the PSA variant with the posterior inferior cerebellar artery arising from the medial limb of the duplication on the left...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28627294/polyphenolic-characterisation-and-bioactivity-of-an-oxalis-pes-caprae-l-leaf-extract
#2
Marisa C Gaspar, Diogo A Fonseca, Manuel J Antunes, Christian Frigerio, Nelson G M Gomes, M Vieira, Armanda E Santos, Maria T Cruz, Maria D Cotrim, Maria G Campos
The present work is focused on the characterisation of the polyphenolic content of an Oxalis pes-caprae L. leaf extract and on the evaluation of its bioactivity with particular interest on its vascular activity and antioxidant potential. The polyphenolic content was characterised by HPLC-DAD and LC-MS/MS. The vascular activity was evaluated according to the influence on the serotonergic and adrenergic systems of the human internal mammary artery (HIMA). Antioxidant and neuroprotective studies were also conducted...
June 18, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28596992/lip-prints-a-study-of-its-uniqueness-among-students-of-mediciti-medical-college
#3
Archana Alzapur, Rajani S Nagothu, Hima B Nalluri
BACKGROUND: "Cheiloscopy" is a technique that deals with lip prints. The pattern of fine creases on the lips are unique to the individual. They are similar to finger prints and useful in crime investigation. AIMS AND OBJECTIVES: To study the uniqueness, prevalence, and gender significance of lip print patterns in human subjects. MATERIALS AND METHODS: The study was conducted on 100 randomly selected male and female undergraduate medical students...
January 2017: Indian Journal of Clinical Anatomy and Physiology
https://www.readbyqxmd.com/read/28572652/pancreatic-carcinoma-diagnosed-by-peroral-pancreatoscopy-using-the-spyglass-system
#4
Sindhu Barola, Hima Tadimeti, Yen-I Chen, Saowanee Ngamruengphong, Mouen A Khashab, Anthony N Kalloo, Vivek Kumbhari
No abstract text is available yet for this article.
June 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28557364/supine-awake-oximetry-as-a-screening-tool-for-daytime-hypercapnia-in-super-obese-patients
#5
Yewon Chung, Frances Louise Garden, Adelle S Jee, Subash Srikantha, Saurabh Gupta, Peter Richard Buchanan, Peter Wallace Collett, Guy Barrington Marks, Hima Vedam
AIMS: To determine the validity of supine awake oximetry as a test for daytime hypercapnia and severe sleep disordered breathing in super-obese patients and to provide evidence to support its use as a screening tool for these disorders in this high-risk patient population. METHODS: Cross-sectional diagnostic test evaluation of super-obese adults (BMI >50 kg/m(2) ) presenting to Liverpool Hospital, Australia, between 2009 and 2015 for diagnostic polysomnography and arterial blood gas measurement...
May 30, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28503309/are-there-two-forms-of-isometric-muscle-action-results-of-the-experimental-study-support-a-distinction-between-a-holding-and-a-pushing-isometric-muscle-function
#6
Laura V Schaefer, Frank N Bittmann
BACKGROUND: In isometric muscle function, there are subjectively two different modes of performance: one can either hold isometrically - thus resist an impacting force - or push isometrically - therefore work against a stable resistance. The purpose of this study is to investigate whether or not two different isometric muscle actions - the holding vs. pushing one (HIMA vs PIMA) - can be distinguished by objective parameters. METHODS: Ten subjects performed two different measuring modes at 80% of MVC realized by a special pneumatic system...
2017: BMC Sports Science, Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28472638/smart-chemistry-based-nanosized-drug-delivery-systems-for-systemic-applications-a-comprehensive-review
#7
REVIEW
Thiruganesh Ramasamy, Hima Bindu Ruttala, Biki Gupta, Bijay Kumar Poudel, Han-Gon Choi, Chul Soon Yong, Jong Oh Kim
This review focuses on the smart chemistry that has been utilized in developing polymer-based drug delivery systems over the past 10years. We provide a comprehensive overview of the different functional moieties and reducible linkages exploited in these systems, and outline their design, synthesis, and application from a therapeutic efficacy viewpoint. Furthermore, we highlight the next generation nanomedicine strategies based on this novel chemistry.
July 28, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28444602/bioactive-guided-fractionation-of-diols-from-streptomyces-sp-msl
#8
Raja Hima Bindhu Madasu, Vijayalakshmi Muvva, Rajesh Kumar Munaganti, Kumar Reddy Dorigondla, Venkateswarlu Yenamandra
An actinomycete strain with a great potential to produce bioactive compounds isolated from a laterite soil was identified as Streptomyces sp. MSL based on 16S rDNA sequence analysis. Secondary metabolites produced by the strain in optimized nutrient broth were extracted and analyzed by chromatographic and spectroscopic techniques. Among the different fractions, four diols, viz., (1) (2R,3R)-2,3-Butanediol, (2) (2R,3S)-2,3-Butanediol, (3) 2,3-dimethyl-2,3-butanediol (Pinacol), and (4) (3R)-1,3-Butanediol exhibited good antimicrobial activity...
May 2017: 3 Biotech
https://www.readbyqxmd.com/read/28440229/pigmented-fungiform-papillae-in-mother-and-daughter
#9
Hima Gopinath, Gatha M Upadya
No abstract text is available yet for this article.
July 2017: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/28414054/endothelium-dependent-vasorelaxant-effect-of-procyanidin-b2-on-human-internal-mammary-artery
#10
Aleksandra Novakovic, Marija Marinko, Goran Jankovic, Ivan Stojanovic, Predrag Milojevic, Dragoslav Nenezic, Vladimir Kanjuh, Qin Yang, Guo-Wei He
The aim of the present study was to investigate and characterize vasorelaxant effect of procyanidin B2 on human internal mammary artery (HIMA) as one of the mechanisms of its protective effect against vascular risk. Procyanidin B2 induced strong concentration-dependent relaxation of HIMA rings pre-contracted by phenylephrine. Pretreatment with L-NAME, a NO synthase inhibitor, hydroxocobalamin, a NO scavenger, and ODQ, an inhibitor of soluble guanylate cyclase, significantly inhibited procyanidin B2-induced relaxation of HIMA, while indomethacin, a cyclooxygenase inhibitor, considerably reduced effects of low concentrations...
July 15, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28411841/the-molecular-revolution-in-cutaneous-biology-the-era-of-genome-wide-association-studies-and-statistical-big%C3%A2-data-and-computational-topics
#11
REVIEW
Hima Anbunathan, Anne M Bowcock
The investigation of biological systems involving all organs of the body including the skin is in era of big data. This requires heavy-duty computational tools, and novel statistical methods. Microarrays have allowed the interrogation of thousands of common genetic markers in thousands of individuals from the same population (termed genome wide association studies or GWAS) to reveal common variation associated with disease or phenotype. These markers are usually single nucleotide polymorphisms (SNPs) that are relatively common in the population...
May 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/28410515/folate-receptor-targeted-hybrid-lipid-core-nanocapsules-for-sequential-delivery-of-doxorubicin-and-tanespimycin
#12
Biki Gupta, Shiva Pathak, Bijay Kumar Poudel, Shobha Regmi, Hima Bindu Ruttala, Milan Gautam, Jong Seong Lee, Jee-Heon Jeong, Han-Gon Choi, Chul Soon Yong, Jong Oh Kim
When exposed to cancer cells, cytotoxic drugs such as doxorubicin (DOX) can lead to the induction of heat shock protein 90 (Hsp90), a molecular chaperone associated with a number of cancer-related client proteins, and result in cell survival. Co-administration of DOX with tanespimycin (TNP), an Hsp90 inhibitor, can sensitize the cancer cells to the cytotoxic effects of DOX. The effect of such a combination has been found to depend on the schedule of administration. Sequential administration of DOX and TNP has been linked to highly synergistic combination effects...
April 6, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28403775/synthesis-and-bioevaluation-of-quaternary-centered-3-hydroxy-3-alkynyl-indolin-2-one-derivatives-as-potential-cytotoxic-agents-and-akt-kinase-inhibitors
#13
Sai Prathima Parvathaneni, Bikshapathi Raktani, Y Poornachandra, Hima Bindu Vittam, G Jagadeeshkumar, Jagadeesh Nanubolu, C Ganesh, Jayathirtha Rao Vaidya
An expeditious approach for direct alkynylation of isatins (ketones) has been developed using tetrabutylammonium fluoride (TBAF) as a catalyst in THF solvent at room temperature under metal-free conditions. Furthermore this method is an economically viable process that also compliments green aspects like being a ligand/metal free process under ambient conditions. This reaction tolerated a wide range of substrates with good to excellent yields (80-94%). All the 3-hydroxy-3-ethynylindolin-2-one derivatives were subjected for in vitro cytotoxic activity on five different cancer cell lines...
April 12, 2017: Anti-cancer Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/28388280/duvelisib-a-phosphoinositide-3-kinase-%C3%AE-%C3%AE-inhibitor-for-chronic-lymphocytic-leukemia
#14
REVIEW
Hima V Vangapandu, Nitin Jain, Varsha Gandhi
Frontline chemotherapy is successful against chronic lymphocytic leukemia (CLL), but results in untoward toxicity. Further, prognostic factors, cytogenetic anomalies, and compensatory cellular signaling lead to therapy resistance or disease relapse. Therefore, for the past few years, development of targeted therapies is on the rise. PI3K is a major player in the B-cell receptor (BCR) signaling axis, which is critical for the survival and maintenance of B cells. Duvelisib, a PI3K δ/γ dual isoform specific inhibitor that induces apoptosis and reduces cytokine and chemokine levels in vitro, holds promise for CLL...
May 2017: Expert Opinion on Investigational Drugs
https://www.readbyqxmd.com/read/28373037/rodent-borne-trypanosoma-from-cities-and-villages-of-niger-and-nigeria-a-special-role-for-the-invasive-genus-rattus
#15
C Tatard, M Garba, P Gauthier, K Hima, E Artige, D K H J Dossou, S Gagaré, G Genson, P Truc, G Dobigny
Although they are known to sometimes infect humans, atypical trypanosomes are very poorly documented, especially in Africa where one lethal case has yet been described. Here we conducted a survey of rodent-borne Trypanosoma in 19 towns and villages of Niger and Nigeria, with a special emphasis on Niamey, the capital city of Niger. The 1298 rodents that were captured yielded 189 qPCR-positive animals from 14 localities, thus corresponding to a 14.6% overall prevalence. Rats, especially black rats, displayed particularly elevated prevalence (27...
April 1, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28353686/genetic-structure-and-invasion-history-of-the-house-mouse-mus-musculus-domesticus-in-senegal-west-africa-a-legacy-of-colonial-and-contemporary-times
#16
C Lippens, A Estoup, M K Hima, A Loiseau, C Tatard, A Dalecky, K Bâ, M Kane, M Diallo, A Sow, Y Niang, S Piry, K Berthier, R Leblois, J-M Duplantier, C Brouat
Knowledge of the genetic make-up and demographic history of invasive populations is critical to understand invasion mechanisms. Commensal rodents are ideal models to study whether complex invasion histories are typical of introductions involving human activities. The house mouse Mus musculus domesticus is a major invasive synanthropic rodent originating from South-West Asia. It has been largely studied in Europe and on several remote islands, but the genetic structure and invasion history of this taxon have been little investigated in several continental areas, including West Africa...
March 29, 2017: Heredity
https://www.readbyqxmd.com/read/28274071/extra-nasopharyngeal-angiofibroma-simulating-a-mucocele-a-new-location-for-the-rare-entity
#17
Srikanth Goud, Tipirisety Swapna, Hima Bindu, Sanjeeva Reddy Gari Shylaja
Angiofibromas are rare, benign, but locally aggressive vascular tumours which account for 0.05-0.5% of all head and neck neoplasms. The common variant of angiofibromas of head and neck region is Juvenile Nasopharyngeal Angiofibroma (JNAF) which is well published in the literature. Incidence of Extranasopharygeal Angiofibromas (ENAF) is relatively rare and most of the published literature favours maxillary sinus as the most common site. We report a rare clinical entity of ENAF involving the upper lip which is first of its kind in the light of literature review owing to its anatomical location...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28259556/a-multi-country-study-to-assess-the-effect-of-a-treatment-with-moxidectin-pour-on-during-the-dry-period-on-milk-production-in-dairy-cows
#18
Thomas Geurden, David J Bartram, Hima Bindu Vanimisetti, Jane Fanke, Philippe Camuset, Jacques Devos, Andrew Sawyer, Georg von Samson-Himmelstjerna, Janina Demeler, Johannes Charlier
A randomized clinical study was conducted in a total of 45 commercial dairy farms in France (14 farms), Germany (28 farms) and the UK (3 farms) to evaluate the effect of an anthelmintic treatment on milk yield in the subsequent lactation. A total of 1287 animals with suspected exposure to Ostertagia ostertagi were included in the study. Animals were treated during the dry period (7-77days before parturition) with moxidectin pour-on (Cydectin(®) 0.5% Pour-On, Zoetis; 638 animals) or left untreated (649 animals) according to a randomized block design...
February 20, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28122339/molecularly-targeted-co-delivery-of-a-histone-deacetylase-inhibitor-and-paclitaxel-by-lipid-protein-hybrid-nanoparticles-for-synergistic-combinational-chemotherapy
#19
Hima Bindu Ruttala, Thiruganesh Ramasamy, Bijay Kumar Poudal, Yongjoo Choi, Ju Yeon Choi, Jeonghwan Kim, Sae Kwang Ku, Han-Gon Choi, Chul Soon Yong, Jong Oh Kim
In this study, a transferrin-anchored albumin nanoplatform with PEGylated lipid bilayers (Tf-L-APVN) was developed for the targeted co-delivery of paclitaxel and vorinostat in solid tumors. Tf-L-APVN exhibited a sequential and controlled release profile of paclitaxel and vorinostat, with an accelerated release pattern at acidic pH. At cellular levels, Tf-L-APVN significantly enhanced the synergistic effects of paclitaxel and vorinostat on the proliferation of MCF-7, MDA-MB-231, and HepG2 cancer cells. Vorinostat could significantly enhance the cytotoxic potential of paclitaxel, induce marked cell apoptosis, alter cell cycle patterns, and inhibit the migratory capacity of cancer cells...
February 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28111215/noni-morinda-citrifolia-l-fruit-juice-reverses-age-related-decline-in-neural-immune-interactions-in-the-spleens-of-old-f344-rats
#20
Uday P Pratap, Lalgi Hima, Hannah P Priyanka, Srinivasan ThyagaRajan
ETHNOPHARMACOLOGICAL RELEVANCE: Various parts of the tropical plant, Morinda citrifolia L. (Noni), have been widely used in traditional medicine in South and Southeast Asia for several centuries. The therapeutic effects of the noni are believed to be mediated through several phytochemicals such as anthraquinones, iridoid, fatty acid glycosides, alcohols, etc. AIM OF THE STUDY: The aim of the study is to investigate the effects of Morinda citrifolia fruit juice (noni fruit juice; NFJ) on neural-immune interactions through the involvement of intracellular signaling pathways both in vitro and in vivo in the splenic lymphocytes of young and old male F344 rats...
February 23, 2017: Journal of Ethnopharmacology
keyword
keyword
101642
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"