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https://www.readbyqxmd.com/read/28077900/prevalence-of-oral-lichen-planus-in-diabetes-mellitus-a-meta-analysis-study
#1
Hamid Reza Mozaffari, Roohollah Sharifi, Masoud Sadeghi
BACKGROUND: Oral lichen planus (OLP) is associated with various other systemic conditions such as hypertension, diabetes mellitus (DM). This study evaluated the prevalence of OLP in DM patients compared with non-diabetic control subjects in a meta-analysis study. METHODS: In this study from January 1973 to August 2016, we searched the studies in Web of Science, Medline/PubMed, Scopus, Science direct, SID (Scientific Information Database), Cochrane and Embase databases...
December 2016: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28074886/post-mortem-whole-exome-analysis-in-a-large-sudden-infant-death-syndrome-cohort-with-a-focus-on-cardiovascular-and-metabolic-genetic-diseases
#2
Jacqueline Neubauer, Maria Rita Lecca, Giancarlo Russo, Christine Bartsch, Argelia Medeiros-Domingo, Wolfgang Berger, Cordula Haas
Sudden infant death syndrome (SIDS) is described as the sudden and unexplained death of an apparently healthy infant younger than one year of age. Genetic studies indicate that up to 35% of SIDS cases might be explained by familial or genetic diseases such as cardiomyopathies, ion channelopathies or metabolic disorders that remained undetected during conventional forensic autopsy procedures. Post-mortem genetic testing by using massive parallel sequencing (MPS) approaches represents an efficient and rapid tool to further investigate unexplained death cases and might help to elucidate pathogenic genetic variants and mechanisms in cases without a conclusive cause of death...
January 11, 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28064421/impact-of-a-randomized-controlled-trial-to-reduce-bedsharing-on-breastfeeding-rates-and-duration-for-african-american-infants
#3
Rachel Y Moon, Anita Mathews, Brandi L Joyner, Rosalind P Oden, Jianping He, Robert McCarter
Bedsharing is associated with both increased breastfeeding and increased risk of sudden and unexpected infant deaths. The objective was to determine impact of sleep location and counseling about sleep location on breastfeeding exclusivity and duration in African-Americans. 1194 mothers of newborns were randomized to receive messaging emphasizing either safe sleep practices to reduce SIDS risk or safe sleep practices to prevent SIDS/suffocation. Mothers completed four interviews in the 6 months after delivery...
January 7, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28062756/phylogenetic-origin-and-diversification-of-rnai-pathway-genes-in-insects
#4
Daniel Dowling, Thomas Pauli, Alexander Donath, Karen Meusemann, Lars Podsiadlowski, Malte Petersen, Ralph S Peters, Christoph Mayer, Shanlin Liu, Xin Zhou, Bernhard Misof, Oliver Niehuis
RNA interference (RNAi) refers to the set of molecular processes found in eukaryotic organisms in which small RNA molecules mediate the silencing or down-regulation of target genes. In insects, RNAi serves a number of functions, including regulation of endogenous genes, anti-viral defense, and defense against transposable elements. Despite being well studied in model organisms, such as Drosophila, the distribution of core RNAi pathway genes and their evolution in insects is not well understood. Here we present the most comprehensive overview of the distribution and diversity of core RNAi pathway genes across 100 insect species, encompassing all currently recognized insect orders...
January 6, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/28053965/the-role-of-oral-contraceptive-pills-on-increased-risk-of-breast-cancer-in-iranian-populations-a-meta-analysis
#5
Ali Soroush, Negin Farshchian, Saeid Komasi, Neda Izadi, Nasrin Amirifard, Afshar Shahmohammadi
BACKGROUND: Cancer is one of the main public health issues in the world. Breast cancer is one of the most common types of cancer among women. It is also the second cause of mortality in women. The association between the use of oral contraceptive pills and breast cancer is controversial and a main issue in public health. Some findings have shown that taking these pills does not have a significant effect in increasing the risk of breast cancer, while others have confirmed the carcinogenic effect of these products...
December 2016: Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28053964/the-evaluation-of-p53-polymorphism-at-codon-72-and-association-with-breast-cancer-in-iran-a-systematic-review-and-meta-analysis
#6
Abozar Soleimani, Yousef Rahmani, Negin Farshchian, Ali Delpisheh, Kivan Khassi, Afshar Shahmohammadi, Nasrin Amirifard
BACKGROUND: Breast cancer is the most common cancer among women in Iran and the world. Multiple environmental factors and genetic variations such as genetic polymorphisms are of its main causes. p53 gene plays an important role in conserving and sustaining the genome as a tumor suppressing gene. Change and polymorphism at codon 72 of p53 gene are correlated with increased risk of lung, mouth, endometrial, prostate, and colorectal cancers, and could be considered an indicator of susceptibility to breast cancer...
December 2016: Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28053119/short-intron-derived-ncrnas
#7
Florent Hubé, Damien Ulveling, Alain Sureau, Sabrina Forveille, Claire Francastel
Introns represent almost half of the human genome, although they are eliminated from transcripts through RNA splicing. Yet, different classes of non-canonical miRNAs have been proposed to originate directly from intron splicing. Here, we considered the alternative splicing of introns as an interesting source of miRNAs, compatible with a developmental switch. We report computational prediction of new Short Intron-Derived ncRNAs (SID), defined as precursors of smaller ncRNAs like miRNAs and snoRNAs produced directly by splicing, and tested their dependence on each key factor in canonical or alternative miRNAs biogenesis (Drosha, DGCR8, DBR1, snRNP70, U2AF65, PRP8, Dicer, Ago2)...
January 3, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28052453/comparison-of-calculated-and-experimentally-determined-sid-of-cp-and-aa-in-complex-diets-differing-in-aa-contents-for-grower-finisher-pigs
#8
K Büsing, A Berk, S Müller, S Kieckhäven, K Krüger, A Zeyner
In practice, the content of standardized ileal digestible AA in complex feeds for pigs is calculated on the basis of tabulated values for individual feedstuffs. It comes into question, however, whether this truly reflects an accurate content based upon the estimate made for the individual feedstuffs. The objective of this study was to compare standardized ileal digestibility (SID) of crude protein (CP) and selected AA in complex feeds for grower and finisher pigs either calculated or experimentally determined...
January 4, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28048201/su-f-t-646-sbrt-lung-moving-beyond-the-3d-conformal-paradigm-with-an-elekta-versahd-accelerator
#9
A Dalhart, D Hyer, B Allen, R Flynn, H Johnston
PURPOSE: To develop a volumetric modulated arc therapy (VMAT) planning and delivery methodology for lung stereotactic body radiation therapy (SBRT) that addresses the unique geometric challenges presented when using an Elekta VersaHD linear accelerator. METHODS: The Elekta VersaHD imaging panels are fixed at 160cm SID when deployed, limiting the ability to perform non-coplanar treatments due to collisions with the treatment table. The panels can be folded in a stored position for non-coplanar treatments, but in this configuration, longitudinal table travel is restricted by the space required for the folded panels...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047737/su-g-tep2-01-can-epid-based-measurement-replace-traditional-daily-output-qa-on-megavoltage-linac
#10
Z Saleh, X Tang, Y Song, C Obcemea, N Beeban, M Chan, X Li, G Tang, S Lim, D Lovelock, T LoSasso, J Mechalakos, S Both
PURPOSE: To investigate the long term stability and viability of using EPID-based daily output QA via in-house and vendor driven protocol, to replace conventional QA tools and improve QA efficiency. METHODS: Two Varian TrueBeam machines (TB1&TB2) equipped with electronic portal imaging devices (EPID) were employed in this study. Both machines were calibrated per TG-51 and used clinically since Oct 2014. Daily output measurement for 6/15 MV beams were obtained using SunNuclear DailyQA3 device as part of morning QA...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046184/nutritive-value-of-extruded-or-multi-enzyme-supplemented-cold-pressed-soybean-cake-for-pigs
#11
T A Woyengo, R Patterson, C L Levesque
The objectives were to determine the standardized ileal digestibility (SID) of AA and NE value of cold-pressed soybean cake (CP-SBC), and the effect of extrusion or adding multi-enzyme to CP-SBC diet for growing pigs. Eight ileal-cannulated pigs (initial BW = 79.7 ± 3.97 kg) were fed 4 diets in a replicated 4 × 4 Latin square design to give 8 replicates per diet. Diets included a cornstarch-based diet with CP-SBC, extruded CP-SBC, and SBC plus multi-enzyme (1,200 U of xylanase, 150 U of glucanase, 500 U of cellulase, 60 U of mannanase, 700 U of invertase, 5,000 U of protease, and 12,000 U of amylase/kilogram of diet; Superzyme-CS, 0...
December 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/28046153/energy-content-and-amino-acid-digestibility-of-flaxseed-expellers-fed-to-growing-pigs
#12
Y F Chen, F Wu, P L Li, Z Q Lyu, L Liu, M B Lyu, F L Wang, C H Lai
This study was conducted to determine the DE and ME as well as the apparent ileal digestibility (AID) and standardized ileal digestibility (SID) of CP and AA in flaxseed expellers fed to growing pigs. In Exp. 1, the DE and ME were determined using 66 crossbred growing pigs (Duroc × Landrace × Yorkshire; 54.2 ± 2.3 kg BW) fed 1 of 11 diets in a completely randomized design. The diets included a corn-soybean meal basal diet and 10 experimental diets containing 29.16% flaxseed expellers supplemented at the expense of corn and soybean meal...
December 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/28043551/the-prevalence-of-tuberculosis-among-iranian-elderly-patients-admitted-to-the-infectious-ward-of-hospital-a-systematic-review-and-meta-analysis
#13
M Azami, K Sayehmiri, M H YektaKooshali, M R HafeziAhmadi
AIMS AND OBJECTIVES: Age increasing is caused physiological changes in the human body, such as reducing the power of the immune system. Weakened immune systems are more susceptible to bacterial infections like tuberculosis. So, this present study was performed for evaluating the prevalence of tuberculosis among Iranian elderly patients admitted to the infectious ward of a hospital. METHODS: This systematic review and meta-analysis study has been done based on PRISMA guidelines...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28042961/determinants-and-barriers-of-helmet-use-in-iranian-motorcyclists-a-systematic-review
#14
Homayoun Sadeghi Bazargani, Mohammad Saadati, Ramin Rezapour, Leili Abedi
BACKGROUND: Use of helmet by motorcyclists decreases the incidence and severity of an injury and its related death. Unfortunately, the helmet use rate is not in an acceptable level in Iran. This study aimed to systematically identify the determinants and barriers of helmet use among Iranian motorcyclists. METHODS: A systematic search of literature was done using PubMed, Scopus, Science Direct and Web of knowledge databases for English literature and SID for Persian articles by specified keywords...
January 1, 2017: Journal of Injury & Violence Research
https://www.readbyqxmd.com/read/28041833/x-ray-structure-based-evaluation-of-analogs-of-citalopram-compounds-with-increased-affinity-and-selectivity-compared-with-r-citalopram-for-the-allosteric-site-s2-on-hsert
#15
Sid Topiol, Benny Bang-Andersen, Connie Sanchez, Per Plenge, Claus J Loland, Karsten Juhl, Krestian Larsen, Peter Bregnedal, Klaus P Bøgesø
The recent publication of X-ray structures of SERT includes structures with the potent antidepressant S-Citalopram (S-Cit). Earlier predictions of ligand binding at both a primary (S1) and an allosteric modulator site (S2), were confirmed. We provide herein examples of a series of Citalopram analogs, showing distinct structure-activity relationship (SAR) at both sites that is independent of the SAR at the other site. Analogs with a higher affinity and selectivity than benchmark R-Citalopram (R-Cit) for the S2 versus the S1 site were identified...
December 21, 2016: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28039683/injury-epidemiology-in-iran-a-systematic-review
#16
Saber Azami-Aghdash, Homayoun Sadeghi-Bazargani, Hosein Shabaninejad, Hassan Abolghasem Gorji
BACKGROUND: Injuries are the second greatest cause of mortality in Iran. Information about the epidemiological pattern of injuries is effective in decision-making. In this regard, the aim of the current study is to elaborate on the epidemiology of injuries in Iran through a systematic review. METHODS: Required data were collected searching the following key words and their Persian equivalents; trauma, injury, accident, epidemiology, prevalence, pattern, etiology, risk factors and Iran...
January 1, 2017: Journal of Injury & Violence Research
https://www.readbyqxmd.com/read/28039682/citicoline-for-traumatic-brain-injury-a-systematic-review-meta-analysis
#17
Ali Meshkini, Mohammad Meshkini, Homayoun Sadeghi-Bazargani
BACKGROUND: Traumatic Brain Injury (TBI) is the leading cause of mortality and morbidity especially in young ages. Despite over 30 years of using Neuroprotective agents for TBI management, there is no absolute recommended agent for the condition yet. METHODS: This study is a part of a scoping review thesis on "Neuroprotective agents using for Traumatic Brain Injury: a systematic review & meta-analyses", which had a wide proposal keywords and ran in "Cochrane CENTRAL", "MedLine/PubMed", "SCOPUS", "Thomson Reuters Web of Science", "SID...
January 1, 2017: Journal of Injury & Violence Research
https://www.readbyqxmd.com/read/28028890/evolution-and-significance-of-the-triple-risk-model-in-sudden-infant-death-syndrome
#18
REVIEW
Jade Spinelli, Lyndsey Collins-Praino, Corinna Van Den Heuvel, Roger W Byard
Sudden infant death syndrome (SIDS) is a leading cause of death in infants, although the mechanisms leading to death remain unclear. Multiple theories have emerged over time, with one of the most influential hypotheses being the triple risk model. This model, first devised in 1972 and later revised in 1994 by Filiano and Kinney, is still widely used in assisting with conceptualising and understanding sudden death in infancy. This model has evolved over time, with each version stressing that SIDS is likely to occur when certain risk factors coincide, suggesting that the lethal mechanisms in SIDS are likely to be multifactorial...
December 28, 2016: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28011333/effect-of-simulation-training-on-the-development-of-nurses-and-nursing-students-critical-thinking-a-systematic-literature-review
#19
REVIEW
Mohsen Adib-Hajbaghery, Najmeh Sharifi
OBJECTIVE: To gain insight into the existing scientific evidence on the effect of simulation on critical thinking in nursing education. DESIGN: A systematic literature review of original research publications. DATA SOURCES: In this systematic review, the papers published in English and Farsi databases of PubMed, Science Direct, ProQuest, ERIC, Google Scholar and Ovid, MagIran and SID, from 1975 to 2015 were reviewed by two independent researchers...
December 20, 2016: Nurse Education Today
https://www.readbyqxmd.com/read/27999640/toxoplasmosis-in-iran-a-guide-for-general-physicians-working-in-the-iranian-health-network-setting-a-systematic-review
#20
REVIEW
Seyed Mohammad Alavi, Leila Alavi
BACKGROUND: Human toxoplasmosis is an important zoonotic infection worldwide which is caused by the intracellular parasite Toxoplasma gondii (T.gondii). The aim of this study was to review briefly the general aspects of toxoplasma infection in in Iranian health system network. METHODS: We searched published toxoplasmosis related articles in English databases including Science Direct, Pub Med, Scopus, Google Scholar, Magiran, Iran Medex, Iran Doc and Scientific Information Database (SID) for toxoplasmosis...
2016: Caspian Journal of Internal Medicine
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