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https://www.readbyqxmd.com/read/28631302/l-hcy-induced-cathepsin-v-mediates-the-vascular-endothelial-inflammation-in-hyperhomocysteinemia
#1
Yi-Ping Leng, Ye-Shuo Ma, Xiao-Gang Li, Rui-Fang Chen, Ping-Yu Zeng, Xiao-Hui Li, Cheng-Feng Qiu, Ya-Pei Li, Zhen Zhang, Alex F Chen
BACKGROUND AND PURPOSE: Vascular inflammation, including the expression of inflammatory cytokines in endothelial cells, plays a critical role in hyperhomocysteinemia-associated vascular diseases. Cathepsin V, specifically expressed in humans, is involved in vascular diseases through its elastolytic and collagenolytic activities. The aim of this study was to determine the effects of cathepsin V on the L-homocysteine (L-Hcy)-induced vascular inflammation. EXPERIMENTAL APPROACH: A high methionine diet-induced hyperhomocysteinemic mice model was used to assess the cathepsin V expression and vascular inflammation...
June 20, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28629481/depression-inflammation-and-memory-loss-among-mexican-americans-analysis-of-the-hable-cohort
#2
Leigh A Johnson, Melissa Edwards, Adriana Gamboa, James Hall, Michelle Robinson, Sid E O'Bryant
BACKGROUND: This study explored the combined impact of depression and inflammation on memory functioning among Mexican-American adults and elders. METHODS: Data were analyzed from 381 participants of the Health and Aging Brain study among Latino Elders (HABLE). Fasting serum samples were collected and assayed in duplicate using electrochemiluminesce on the SECTOR Imager 2400A from Meso Scale Discovery. Positive DepE (depression endophenotype) was codified as any score >1 on a five-point scale based on the GDS-30...
June 20, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28617463/robust-wireless-power-transfer-using-a-nonlinear-parity-time-symmetric-circuit
#3
Sid Assawaworrarit, Xiaofang Yu, Shanhui Fan
Considerable progress in wireless power transfer has been made in the realm of non-radiative transfer, which employs magnetic-field coupling in the near field. A combination of circuit resonance and impedance transformation is often used to help to achieve efficient transfer of power over a predetermined distance of about the size of the resonators. The development of non-radiative wireless power transfer has paved the way towards real-world applications such as wireless powering of implantable medical devices and wireless charging of stationary electric vehicles...
June 14, 2017: Nature
https://www.readbyqxmd.com/read/28615326/prenatal-nicotinic-exposure-prolongs-superior-laryngeal-c-fiber-mediated-apnea-and-bradycardia-through-enhancing-neuronal-trpv1-expression-and-excitation
#4
Xiuping Gao, Lei Zhao, Jianguo Zhuang, Na Zang, Fadi Xu
Maternal cigarette smoke, including prenatal nicotinic exposure (PNE), is responsible for sudden infant death syndrome (SIDS). The fatal events of SIDS are characterized by severe bradycardia and life-threatening apneas. Although activation of transient receptor potential vanilloid 1 (TRPV1) of superior laryngeal C-fibers (SLCFs) could induce bradycardia and apnea and has been implicated in SIDS pathogenesis, how PNE affects the SLCF-mediated cardiorespiratory responses remains unexplored. Here, we tested the hypothesis that PNE would aggravate the SLCF-mediated apnea and bradycardia via up-regulating TRPV1 expression and excitation of laryngeal C-neurons in the nodose/jugular (N/J) ganglia...
June 14, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28608686/targeted-metabolic-profiling-of-post-mortem-brain-from-infants-who-died-from-sudden-infant-death-syndrome
#5
Stewart F Graham, Onur Turkoglu, Praveen Kumar, Ali Yilmaz, Trent C Bjorndahl, BeomSoo Han, Rupasri Mandal, David S Wishart, Ray O Bahado-Singh
Currently little is known about the underlying pathophysiology associated with SIDS, and no objective biomarkers exist for the accurate identification of those at greatest risk of dying from SIDS. Using targeted metabolomics, we aim to profile the medulla oblongata of infants who have died from SIDS (n = 16) and directly compare their biochemical profile with age matched controls. Combining data acquired using (1)H NMR and targeted DI-LC-MS/MS, we have identified fatty acid oxidation as a pivotal biochemical pathway perturbed in the brains of those infants who have from SIDS (p = 0...
June 20, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28602839/epidemiology-of-brucellosis-in-iran-a-comprehensive-systematic-review-and-meta-analysis-study
#6
REVIEW
Reza Mirnejad, Faramarz Masjedian Jazi, Shayan Mostafaei, Mansour Sedighi
Brucellosis is still one of the most challenging issues for health and the economy in many developing countries such as Iran. Considering the high prevalence of brucellosis, the aim of the current study was to systematically review published data about the annual incidence rate of this infection from different parts of Iran and provide an overall relative frequency (RF) for Iran using meta-analysis. We searched several databases including PubMed, ISI Web of Science, Scopus, google scholar, IranMedex and Iranian Scientific Information Database (SID) by using the following keywords: "Brucella", "Brucellosis", "Malta fever", "Mediterranean fever", "undulant fever", "zoonosis" and "Iran" in Title/Abstract/Keywords fields...
June 7, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28593563/spatio-temporal-monitoring-of-cotton-cultivation-using-ground-based-and-airborne-multispectral-sensors-in-gis-environment
#7
Antonis Papadopoulos, Dionissios Kalivas, Sid Theocharopoulos
Multispectral sensor capability of capturing reflectance data at several spectral channels, together with the inherent reflectance responses of various soils and especially plant surfaces, has gained major interest in crop production. In present study, two multispectral sensing systems, a ground-based and an aerial-based, were applied for the multispatial and temporal monitoring of two cotton fields in central Greece. The ground-based system was Crop Circle ACS-430, while the aerial consisted of a consumer-level quadcopter (Phantom 2) and a modified Hero3+ Black digital camera...
July 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28593499/in-utero-exposure-to-nicotine-alters-the-development-of-the-rabbit-cardiac-conduction-system-and-provides-a-potential-mechanism-for-sudden-infant-death-syndrome
#8
Anh Tuan Ton, Michael Biet, Jean-Francois Delabre, Nathalie Morin, Robert Dumaine
In-utero exposure to tobacco smoke remains the highest risk factor for sudden infant death syndrome (SIDS). To alleviate the risks, nicotine replacement therapies are often prescribed to women who wish to quit smoking during their pregnancy. Cardiac arrhythmias is considered the final outcome leading to sudden death. Our goal in this study was to determine if exposing rabbit fetus to nicotine altered the cardiac conduction system of newborn kittens in a manner susceptible to cause SIDS. Using neuronal markers and a series of immunohistological and electrophysiological techniques we found that nicotine delayed the development of the cardiac pacemaker center (sinoatrial node) and decreased its innervation...
June 7, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/28589871/prevalence-of-cystic-echinococcosis-in-iran-a-systematic-review-and-meta-analysis
#9
H R Khalkhali, M Foroutan, S Khademvatan, H Majidiani, S Aryamand, P Khezri, A Aminpour
As a significant zoonosis, cystic echinococcosis (CE) is endemic in some parts of the world, such as the Middle East. There are studies on the prevalence of this infection in animal and human reservoirs in Iran; hence, we conducted this meta-analysis to elucidate the prevalence of CE in Iran. English (PubMed, Scopus, Web of Science, Science Direct and Google Scholar) and Persian (Magiran, Iran Medex, Iran Doc and SID) databases were explored. In the case of definitive, animal and human intermediate hosts, 37, 90 and 33 studies, respectively, have been included in the current review from January 1990 to December 2015...
June 7, 2017: Journal of Helminthology
https://www.readbyqxmd.com/read/28580444/maternal-anemia-during-pregnancy-and-infant-low-birth-weight-a-systematic-review-and-meta-analysis
#10
REVIEW
Shoboo Rahmati, Ali Delpishe, Milad Azami, Mohammed Reza Hafezi Ahmadi, Kurosh Sayehmiri
BACKGROUND: Infant low birth weight is one of the major problems in different societies. Different reports have provided different results regarding the relationship between maternal anemia and infant low birth weight in different months of pregnancy. OBJECTIVE: The aim of this study was to determine the relationship between maternal anemia during pregnancy and infant low birth weight. MATERIALS AND METHODS: This systematic review was conducted using related keywords in national (Sid, Iran...
March 2017: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/28573795/digestible-indispensable-amino-acid-score-diaas-and-protein-digestibility-corrected-amino-acid-score-pdcaas-in-oat-protein-concentrate-measured-in-20-to-30-kilogram-pigs
#11
Jerubella J Abelilla, Yanhong Liu, Hans H Stein
BACKGROUND: Oat protein concentrate is often used in human food, but the quality of this protein has not been characterized. Therefore, the objectives of this experiment were to determine the standardized ileal digestibility (SID) of crude protein (CP) and amino acids (AA) in oat protein concentrate and to determine differences in protein quality estimates between the protein digestibility-corrected AA score (PDCAAS) and the digestible indispensable AA score (DIAAS) when using growing pigs for both measurements...
June 2, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28572950/relative-validation-of-a-short-questionnaire-to-assess-the-dietary-habits-of-pregnant-american-indian-women
#12
Terryl J Hartman, Amy J Elliott, Jyoti Angal, Torin Block, Erin P Ferranti, Diane C Mitchell, Dana C Nickleach, Jean C Norris, Rosalind A Breslow
The objective of this study was to compare a short dietary screener developed to assess diet quality with interviewer-administered telephone 24-hour dietary recalls in a population of pregnant Northern Plains (NP) American Indian women. Participants were recruited from NP clinical sites of the Prenatal Alcohol and SIDS and Stillbirth (PASS) Network, as part of a large, prospective, multidisciplinary study. Prenatal PASS participants who enrolled prior to 24 weeks gestation were eligible to participate. Repeated 24-hour dietary recalls were collected using the Nutrition Data System for Research (NDSR) software and a short dietary screener was administered intended to capture usual dietary intake during pregnancy...
May 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28562296/race-ethnicity-and-sids
#13
Richard D Goldstein, Hannah C Kinney
No abstract text is available yet for this article.
May 15, 2017: Pediatrics
https://www.readbyqxmd.com/read/28555503/spontaneous-isolated-dissection-and-atherosclerotic-plaques-of-superior-mesenteric-artery-the-vastly-different-occurrence-site-suggests-the-opposite-hemodynamic-etiology
#14
Zhi-Gang Min, Hai-Rong Shan, Long Xu, Su Yan, Xue-Xia Sheng, Jian Ji, Zhi-Hong Cao
OBJECTIVES: The development of atherosclerotic plaques and spontaneous isolated dissection (SID) of superior mesenteric artery (SMA) were considered to be related to opposite hemodynamics. The purpose of this study was to compare their occurrence site and morphology of SMA to confirm the hemodynamic etiology. METHODS: Fifty-seven patients with SID and 64 patients with atherosclerotic plaques were compared about patient characteristics, location, distance from lesion to the aortic ostia, branching angle and inlet diameter of SMA...
May 30, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28549309/switching-between-intravenous-and-subcutaneous-trastuzumab-safety-results-from-the-prefher-trial
#15
Joseph Gligorov, Giuseppe Curigliano, Volkmar Müller, Ann Knoop, Valerie Jenkins, Sunil Verma, Stuart Osborne, Sabine Lauer, Zuzana Machackova, Lesley Fallowfield, Xavier Pivot
AIM: To assess the safety and tolerability of switching between subcutaneous (SC) and intravenous (IV) trastuzumab in the PrefHer study (NCT01401166). PATIENTS AND METHODS: Patients with HER2-positive early breast cancer completed (neo)adjuvant chemotherapy and were randomised to receive four cycles of SC trastuzumab, via single-use injection device (SID; Cohort 1) or hand-held syringe (Cohort 2), followed by four cycles of IV, or vice versa (the crossover period presented here) as part of their 18 standard cycles of adjuvant trastuzumab treatment...
May 23, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28546938/prevalence-of-diabetic-retinopathy-in-iran-a-systematic-review-and-meta-analysis
#16
Saman Maroufizadeh, Amir Almasi-Hashiani, Mostafa Hosseini, Mahdi Sepidarkish, Reza Omani Samani
AIM: To estimate the overall prevalence of diabetic retinopathy (DR) in Iran by a systematic review and Meta-analysis. METHODS: We conducted a search of all published literature on diabetic patients for the prevalence of DR using Web of Sciences, PubMed, Scopus, Google Scholar, and national electronic databases SID, Magiran, and Iranmedex from their inception until September 2016 with standard keywords. Pooled estimates of the DR prevalence and the corresponding 95% confidence intervals (CI) were calculated using random effects models...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28545556/finer-leaf-resolution-and-steeper-beam-edges-using-a-virtual-isocentre-in-concurrence-to-ptv-shaped-collimators-in-standard-distance-a-planning-study
#17
Klaus Bratengeier, Barbara Herzog, Sonja Wegener, Kostyantyn Holubyev
PURPOSE: Investigation of a reduced source to target distance to improve organ at risk sparing during stereotactic irradiation (STX). METHODS: The authors present a planning study with perfectly target-volume adapted collimator compared with multi-leaf collimator (MLC) at reduced source to virtual isocentre distance (SVID) in contrast to normal source to isocentre distance (SID) for stereotactic applications. The role of MLC leaf width and 20-80% penumbra was examined concerning the healthy tissue sparing...
May 25, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28540261/prevalence-of-metabolic-syndrome-among-iranian-population-a-systematic-review-and-meta-analysis
#18
REVIEW
Sahar Dalvand, Seyed Hassan Niksima, Reza Meshkani, Reza Ghanei Gheshlagh, Sahar Sadegh-Nejadi, Wesam Kooti, Naser Parizad, Hossein Zahednezhad, Reza Afrisham
BACKGROUND: Metabolic syndrome (MetS) is the major risk factor for development of type 2 diabetes and cardiovascular diseases in different populations. The aim of this study was to evaluate the prevalence of MetS among Iranian population. METHODS: Thirty-four cross-sectional studies were analyzed with a sample of 83227 people. National and international English electronic databases (PubMed, Google scholar, Web of Science, Science Direct, and Scopus) and Persian language databases (SID, Medlib, Iran medex, Magiran, Medlib, and IranDoc) were used to search the articles published on MetS in Iranian population from Jan 2005 to May 2016...
April 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28540260/the-quality-of-educational-services-from-students-viewpoint-in-iran-a-systematic-review-and-meta-analysis
#19
REVIEW
Ahmad Moosavi, Mohammad Mohseni, Hajar Ziaiifar, Saber Azami-Aghdash, Mahdi Gharasi Manshadi, Aziz Rezapour
BACKGROUND: Students' view is an important factor in assessing the quality of universities. Servqual pattern is regarded as the most prominent for services quality measurement. This study aimed to review systematically studies that investigated the quality of educational services. METHODS: A systematic review and meta-analysis of studies evaluating students' viewpoint about quality of educational services were conducted. Required data were collected from PubMed, Embase, Scopus, Science Direct, Google Scholar, SID, Magiran, and Iranmedex, without time restriction...
April 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28540222/penile-fracture-epidemiology-diagnosis-and-management-in-iran-a-narrative-review
#20
REVIEW
Majid Mirzazadeh, Morteza Fallahkarkan, Jalil Hosseini
Penile fracture (PF) is considered an emergency in urology. In the literature there are some case series reporting considerable incidence of PF in some parts of Iran. There are no accurate data about the incidence of PF all around Iran. Although it may be uncommon in other parts of the country and in the other countries, it can also be underreported. There are some challenges in diagnosis, management, and also reporting of these cases. In this review of Iranian medical literature, we searched for penile fracture and penile injury keywords in Medline, Scopus, SID, Google and Persian medical journals...
April 2017: Translational Andrology and Urology
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