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"vitamin D deficiency"

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https://www.readbyqxmd.com/read/27914137/is-vitamin-d-an-independent-risk-factor-of-nonalcoholic-fatty-liver-disease-a-cross-sectional-study-of-the-healthy-population
#1
Danbee Park, Hyuktae Kwon, Seung Won Oh, Hee Kyung Joh, Seung Sik Hwang, Jin Ho Park, Jae Moon Yun, Hyejin Lee, Goh Eun Chung, Sangjoon Ze, Jae Hong Park, Yeseul Bae, Arang Lee
The association between vitamin D levels and nonalcoholic fatty liver disease (NAFLD) has been recognized. However, few studies showed independent associations between vitamin D deficiency and NAFLD after a sex-related adjustment for metabolic factors. We aimed to study whether vitamin D deficiency is an independent risk factor of NAFLD even after controlling for metabolic syndrome and visceral fat in both sexes. In this cross-sectional study, 7,514 Korean adults (5,278 men, 2,236 women) participated in a health check-up program...
January 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27913273/the-endocrine-vitamin-d-system-in-the-gut
#2
Antonio Barbáchano, Asunción Fernández-Barral, Gemma Ferrer-Mayorga, Alba Costales-Carrera, María Jesús Larriba, Alberto Muñoz
The active vitamin D metabolite 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) has important regulatory actions in the gut through endocrine and probably also intracrine, autocrine and paracrine mechanisms. By activating the vitamin D receptor (VDR), which is expressed at a high level in the small intestine and colon, 1,25(OH)2D3 regulates numerous genes that control gut physiology and homeostasis. 1,25(OH)2D3 is a major responsible for epithelial barrier function and calcium and phosphate absorption, and the host's defense against pathogens and the inflammatory response by several types of secretory and immune cells...
November 29, 2016: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/27910985/uvb-radiation-vitamin-d-and-multiple-sclerosis
#3
H F DeLuca, L Plum
Acheson et al. (1960) observed an inverse relationship between sunlight exposure and the incidence of Multiple Sclerosis (MS). This led to the suggestion that increased levels of vitamin D caused by sunlight in some way suppresses MS. Further, super physiological doses of the metabolically active metabolite of vitamin D, i.e. 1α,25 dihydroxy vitamin D suppresses the animal model of MS i.e. experimental autoimmune encephalomyelitis (EAE). However, this response was accompanied by hypercalcemia. Hypercalcemia itself can suppress EAE...
December 2, 2016: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/27904949/association-of-arthritis-and-vitamin-d-insufficiency-with-physical-disability-in-mexican-older-adults-findings-from-the-mexican-health-and-aging-study
#4
Luis M Valderrama-Hinds, Soham Al Snih, Martin A Rodriguez, Rebeca Wong
Arthritis and vitamin D insufficiency are prevalent in older adults and are risk factors for disability. The objective of this study was to examine the effect of co-occurring arthritis and vitamin D deficiency on upper-lower extremity functional limitations and disability in older adults. We examined 1533 participants aged ≥50 years from a subsample of the Mexican Health and Aging Study. Measures included sociodemographics, body mass index, comorbid conditions, falls, physical activity, physical function tests, functional limitations, activities of daily living (ADL), and vitamin D...
November 30, 2016: Rheumatology International
https://www.readbyqxmd.com/read/27904620/the-relationship-between-vitamin-d-clinical-outcomes-and-mortality-rate-in-icu-patients-a-prospective-observational-study
#5
Nooshin Vosoughi, Parviz Kashefi, Behnood Abbasi, Awat Feizi, Gholamreza Askari, Leila Azadbakht
BACKGROUND: According to the high prevalence of Vitamin D deficiency, a few studies have been conducted to clarify the relationship between 25-hydroxyvitamin D (25(OH)D) and clinical outcomes in critically ill patients. The objective of this study was to determine this probable association. MATERIALS AND METHODS: Serum 25(OH)D, C-reactive protein, malnutrition measurements, and Intensive Care Unit (ICU)-acquired infection from 185 patients in ICU were assessed in the first 24 h of admission and they were followed for the other outcomes...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27904548/the-effect-of-vitamin-d-supplementation-on-gestational-diabetes-in-high-risk-women-results-from-a-randomized-placebo-controlled-trial
#6
Shole Shahgheibi, Fariba Farhadifar, Bahar Pouya
BACKGROUND: Vitamin D deficiency is common in pregnancy, leading to increase in the frequency of preeclampsia, cesarean delivery, neonatal bacterial vaginosis, and gestational diabetes. The current study was designed and implemented to investigate the effect of vitamin D during the first and second trimesters of pregnancy in reducing the risk of gestational diabetes mellitus (GDM) in women who are at high risk [history of GDM, birth macrosomia, family history, and high body mass index (BMI)]...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27904547/the-effect-of-vitamin-d-administration-on-serum-leptin-and-adiponectin-levels-in-end-stage-renal-disease-patients-on-hemodialysis-with-vitamin-d-deficiency-a-placebo-controlled-double-blind-clinical-trial
#7
Afsoon Emami Naini, Sahar Vahdat, Zahra Parin Hedaiati, Safoura Shahzeidi, Amir Hossein Pezeshki, Hamid Nasri
BACKGROUND: The prevalence of vitamin D deficiency is higher in end-stage renal disease (ESRD) patients compared to healthy populations. This deficiency could lead to several complications with different mechanisms and might result in reduced survival in patients. Leptin and adiponectin are messenger proteins with endocrine secretion from adipocytes and various effects in cellular mechanisms. The goal of this study was to find the effect of vitamin D administration on serum levels of leptin and adiponectin in ESRD patients...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27902451/vitamin-d-and-male-reproductive-system
#8
Pablo R Costanzo, Pablo Knoblovits
Vitamin D deficiency is a highly prevalent worldwide condition and affects people of all ages. The most important role of vitamin D is the regulation of intestinal calcium absorption and metabolism of calcium and phosphorus to maintain muscle and bone homeostasis. Furthermore, in recent years it has been discovered that the vitamin D receptor (VDR) is widely distributed in many organs and tissues where vitamin D can perform other actions that include the modulation of the immune response, insulin secretion, anti-proliferative effect on cells of vascular smooth muscle, modulation of the renin-angiotensin-aldosterone system and regulates cell growth in several organs...
December 1, 2016: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/27900428/relationship-between-baseline-characteristics-and-response-to-risedronate-treatment-for-osteoporosis-data-from-three-japanese-phase-iii-trials
#9
T Mawatari, R Muraoka, Y Iwamoto
: We evaluated the influence of baseline age, bone mineral density (BMD), and serum levels of vitamin D on the response to risedronate treatment. Risedronate consistently increased BMD, but our results suggest vitamin D supplementation may be necessary to achieve optimal treatment effect. Furthermore, early intervention may help prevent bone fractures. INTRODUCTION: We aimed to investigate the influence of baseline age, BMD, and vitamin D insufficiency on the response to risedronate treatment...
November 30, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27900269/vitamin-d-and-spine-surgery
#10
REVIEW
Thomas Mabey, Weerasak Singhatanadgige, Wicharn Yingsakmongkol, Worawat Limthongkul, Sittisak Honsawek
Vitamin D is crucial for musculoskeletal health, maintenance, and function. Vitamin D insufficiency is common among patients undergoing spine surgery and the ideal vitamin D level for spine surgery has yet to be investigated. There is a high prevalence of hypovitaminosis D in patients with musculoskeletal pain regardless of surgical intervention. With the frequency and costs of spine surgery increasing, it is imperative that efforts are continued to reduce the impact on patients and healthcare services. Studies into vitamin D and its associations with orthopaedic surgery have yielded alarming findings with regards to the prevalence of vitamin D deficiency...
November 18, 2016: World Journal of Orthopedics
https://www.readbyqxmd.com/read/27898926/assessment-of-serum-25-hydroxyvitamin-d-concentrations-of-beef-cows-and-calves-across-seasons-and-geographical-locations
#11
C D Nelson, J L Powell, D M Price, M J Hersom, J V Yelich, M E Drewnoski, S L Bird, G Allen Bridges
Vitamin D is critical for the growth and development of calves and positively contributes to immune function of cattle. Serum 25-hydroxyvitamin D (25(OH)D) concentrations above 20 ng/mL have traditionally been considered adequate for growth and development of cattle, but recent evidence has indicated that concentrations below 30 ng/mL are insufficient for immunity. Because little information is available regarding vitamin D status of beef cattle, the objective of this study was to evaluate vitamin D status of beef cow-calf herds on pasture as affected by season and location...
September 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27897409/association-of-serum-vitamin-d-with-osteosarcopenic-obesity-korea-national-health-and-nutrition-examination-survey-2008-2010
#12
Jinhee Kim, Yunhwan Lee, Seunghee Kye, Yoon-Sok Chung, Okhee Lee
BACKGROUND: Serum vitamin D levels have been reported to be associated with individual components of body composition. However, the relationship between serum vitamin D and combined indices of adverse body composition is largely unknown. This cross-sectional study examined the association between serum vitamin D and osteosarcopenic obesity in a nationally representative sample of middle-aged and older adults. METHODS: We analysed the Korea National Health and Nutrition Examination Surveys (IV and V) conducted in 2008-2010, consisting of 5908 (2485 men, 3423 women) aged ≥ 50 years...
October 5, 2016: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/27895587/vitamin-d-signaling-through-induction-of-paneth-cell-defensins-maintains-gut-microbiota-and-improves-metabolic-disorders-and-hepatic-steatosis-in-animal-models
#13
Danmei Su, Yuanyang Nie, Airu Zhu, Zishuo Chen, Pengfei Wu, Li Zhang, Mei Luo, Qun Sun, Linbi Cai, Yuchen Lai, Zhixiong Xiao, Zhongping Duan, Sujun Zheng, Guihui Wu, Richard Hu, Hidekazu Tsukamoto, Aurelia Lugea, Zhenqui Liu, Stephen J Pandol, Yuan-Ping Han
Metabolic syndrome (MetS), characterized as obesity, insulin resistance, and non-alcoholic fatty liver diseases (NAFLD), is associated with vitamin D insufficiency/deficiency in epidemiological studies, while the underlying mechanism is poorly addressed. On the other hand, disorder of gut microbiota, namely dysbiosis, is known to cause MetS and NAFLD. It is also known that systemic inflammation blocks insulin signaling pathways, leading to insulin resistance and glucose intolerance, which are the driving force for hepatic steatosis...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27895486/factors-associated-with-vitamin-d-status-of-low-income-hospitalized-psychiatric-patients-results-of-a-retrospective-study
#14
Alessandra N Bazzano, Lisa Littrell, Stephen Lambert, Cody Roi
BACKGROUND: Recent evidence has indicated a potential role of vitamin D3 in a range of neuropsychiatric outcomes, as well as on cognitive function, but conflicting data have left that role uncertain. Understanding potential associations of vitamin D status with psychiatric illness will allow clinicians to better assess therapeutic options. Few studies have examined vitamin D status among a racially diverse group of psychiatric patients who have been hospitalized, and none has done so in the southern US where socioeconomic inequality is high...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27895322/gestational-vitamin-d-deficiency-and-autism-related-traits-the-generation-r-study
#15
A A E Vinkhuyzen, D W Eyles, T H J Burne, L M E Blanken, C J Kruithof, F Verhulst, V W Jaddoe, H Tiemeier, J J McGrath
There is intense interest in identifying modifiable risk factors associated with autism-spectrum disorders (ASD). Autism-related traits, which can be assessed in a continuous fashion, share risk factors with ASD, and thus can serve as informative phenotypes in population-based cohort studies. Based on the growing body of research linking gestational vitamin D deficiency with altered brain development, this common exposure is a candidate modifiable risk factor for ASD and autism-related traits. The association between gestational vitamin D deficiency and a continuous measure of autism-related traits at ~6 years (Social Responsiveness Scale; SRS) was determined in a large population-based cohort of mothers and their children (n=4229)...
November 29, 2016: Molecular Psychiatry
https://www.readbyqxmd.com/read/27894744/-vitamin-d-deficiency-and-morbimortality-in-critically-ill-paediatric-patients
#16
Patricia García-Soler, Antonio Morales-Martínez, Vanessa Rosa-Camacho, Juan Antonio Lillo-Muñoz, Guillermo Milano-Manso
OBJECTIVES: To determine the prevalence and risks factors of vitamin D deficiency, as well as its relationship with morbidity and mortality in a PICU. MATERIAL AND METHODS: An observational prospective study in a tertiary children's University Hospital PICU conducted in two phases: i: cohorts study, and ii: prevalence study. The study included 340 critically ill children with ages comprising 6 months to 16 years old. EXCLUSION CRITERIA: Chronic kidney disease, known parathyroid disorders, and vitamin D supplementation...
November 25, 2016: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/27893863/high-vitamin-d-consumption-is-inversely-associated-with-cardiovascular-disease-risk-in-an-urban-mexican-population
#17
Paloma Muñoz-Aguirre, Edgar Denova-Gutiérrez, Mario Flores, Eduardo Salazar-Martínez, Jorge Salmerón
BACKGROUND: Vitamin D deficiency is a major global public health problem. Recent epidemiological studies have assessed the relationship between vitamin D and multiple outcomes, including cardiovascular disease. However, this evidence is limited and inconclusive. Our purpose in this study was to evaluate the association between dietary vitamin D intake and cardiovascular disease risk in adult Mexican population. METHODS: We conducted a cross-sectional analysis with the baseline data from 6294 men and women aged 20-80 years participating in the Health Workers Cohort Study...
2016: PloS One
https://www.readbyqxmd.com/read/27889807/vitamin-d-status-in-bosnia-and-herzegovina-the-cross-sectional-epidemiological-analysis
#18
S Sokolovic, R Alimanovic-Alagic, L Dzananovic, S Cavaljuga, N Beslic, E Ferhatbegovic-Opankovic
RATIONALE: Vitamin D deficiency/insufficiency/ is a worldwide epidemic in general population. The investigation of vitamin D concentrations in Bosnia and Herzegovina has never been conducted. MAIN RESULTS: A total of 82% from 2483 examined patients have deficient/insufficient/ Vitamin D level. SIGNIFICANCE: These results encourage future studies to be focused on more specific details. INTRODUCTION: The goal of this paper was to evaluate the vitamin D concentrations in different cohort patients...
November 26, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27889723/vitamin-d-supplementation-for-treatment-and-prevention-of-pneumonia-in-under-five-children-a-randomized-double-blind-placebo-controlled-trial
#19
Piyush Gupta, Pooja Dewan, Dheeraj Shah, Nisha Sharma, Nidhi Bedi, Iqbal R Kaur, Ajay Kumar Bansal, S V Madhu
OBJECTIVE: To evaluate the efficacy of single oral mega-dose of Vitamin D3 for treatment and prevention of pneumonia in under-five children. DESIGN: Randomized, double blind, placebo-controlled trial. SETTING: Tertiary-care hospital. PARTICIPANTS: 324 children (of 980 assessed) between 6 mo-5 y age (median (IQR): 12 (7,19.8) mo) with WHO-defined severe pneumonia. Of these, 126 (39%) were vitamin D deficient (serum 25(OH)D <12 ng/mL)...
November 15, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/27888492/vitamin-d-deficiency-in-early-implant-failure-two-case-reports
#20
Tobias Fretwurst, Sebastian Grunert, Johan P Woelber, Katja Nelson, Wiebke Semper-Hogg
An association between vitamin D deficiency and early dental implant failure is not properly verified, but its role in osteoimmunology is discussed. This article illustrates two case reports with vitamin D deficiency and early implant failure. Prior to implant placement, the first patient received crestal bone grafting with autologous material. Both patients received dental implants from different manufacturers in the molar region of the mandible. In the case of bone grafting in the first patient, all implants were placed in a two-stage procedure...
December 2016: International Journal of Implant Dentistry
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