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Keywords antibiotics universal group b ...

antibiotics universal group b strep

https://read.qxmd.com/read/36935773/genotype-distribution-and-antibiotic-susceptibility-pattern-of-clinical-isolates-of-group-b-streptococcus-in-a-tertiary-care-hospital-in-puducherry-south-india
#21
JOURNAL ARTICLE
A V Sangeetha, Sheela Devi, Anandhalakshmi Subramanian, Mary Daniel, Perumal Anandh
BACKGROUND: Streptococcus agalactiae apart from being a colonizer in the genital region is also associated with several other invasive infections in all age groups. With the varied distribution of serotypes across different regions of the world, universal vaccination is also unattainable. However, in India, the knowledge of group B Streptococcus (GBS) genotype distribution is deficient. Thus, this study was initiated to add data on this aspect. Methodology . A cross-sectional study was conducted using isolates of group B Streptococcus from all clinical specimens...
2023: Journal of Tropical Medicine
https://read.qxmd.com/read/36843196/characterization-of-the-salivary-microbiome-before-and-after-antibiotic-therapy-via-separation-technique
#22
JOURNAL ARTICLE
Katarzyna Pauter-Iwicka, Viorica Railean, Michał Złoch, Paweł Pomastowski, Małgorzata Szultka-Młyńska, Dominika Błońska, Wojciech Kupczyk, Bogusław Buszewski
In the present research, the MALDI-TOF MS technique was applied as a tool to rapidly identify the salivary microbiome. In this fact, it has been monitored the changes occurred in molecular profiles under different antibiotic therapy. Significant changes in the composition of the salivary microbiota were noticed not only in relation to the non antibiotic (non-AT) and antibiotic treatment (AT) groups, but also to the used media, the antibiotic therapy and co-existed microbiota. Each antibiotic generates specific changes in molecular profiles...
February 27, 2023: Applied Microbiology and Biotechnology
https://read.qxmd.com/read/36671301/national-surveillance-of-tetracycline-erythromycin-and-clindamycin-resistance-in-invasive-streptococcus-pyogenes-a-retrospective-study-of-the-situation-in-spain-2007-2020
#23
JOURNAL ARTICLE
Pilar Villalón, Marta Bárcena, María José Medina-Pascual, Noelia Garrido, Silvia Pino-Rosa, Gema Carrasco, Sylvia Valdezate
BACKGROUND: This work reports on antimicrobial resistance data for invasive Streptococcus pyogenes in Spain, collected by the 'Surveillance Program for Invasive Group A Streptococcus ', in 2007-2020. METHODS: emm typing was determined by sequencing. Susceptibility to penicillin, tetracycline, erythromycin, and clindamycin was det erm ined via the E-test. tet M, tet O, msr D, mef A, erm B, erm TR, and erm T were sought by PCR. Macrolide-resistant phenotypes (M, cMLSB, and iMLSB) were detected using the erythromycin-clindamycin double-disk test...
January 6, 2023: Antibiotics
https://read.qxmd.com/read/36472424/multicenter-evaluation-of-the-cepheid-xpert-gbs-lb-xc-test
#24
MULTICENTER STUDY
Phyu M Thwe, Matthew L Faron, David T Pride, Amorina Cruz, Derek Gerstbrein, Karen A Nahmod, Lindsay Bigham, Xiaotang Du, Xixi Lu, Stephanie Moya, Ping Ren
Early-onset neonatal sepsis due to Streptococcus agalactiae (group B Streptococcus [GBS]) infection is one of the leading causes of newborn mortality and morbidity. The latest guidelines published in 2019 recommended universal screening of GBS colonization among all pregnant women and intrapartum antibiotic prophylaxis for positive GBS. The updated procedures allow rapid molecular-based GBS screening using nutrient broth-enriched rectovaginal samples. Commercially available molecular assays for GBS diagnosis target mainly the cfb gene, which encodes a hemolysin protein responsible for producing the Christie-Atkins-Munch-Petersen (CAMP) factor...
December 21, 2022: Journal of Clinical Microbiology
https://read.qxmd.com/read/36306123/prevalence-of-group-b-streptococcus-in-pregnant-women-in-kerala-and-relation-to-neonatal-outcomes-a-prospective-cross-sectional-study
#25
JOURNAL ARTICLE
Girija Gurudas, Rajalakshmi Arjun, Naveen Jain, Vidyalekshmy Ranganayaki, Chinnu Sasikumar, Viji Mohan, Febeena Hussain, Femitha Pournami
BACKGROUND AND OBJECTIVES: Early onset sepsis (EOS) in neonates is a scourge that contributes to morbidity and mortality. Prominent stakeholders recommend universal screening of antenatal women for Group B Streptococcus (GBS) and intrapartum antibiotic prophylaxis (IAP) for those who are carriers. However, there are controversies. Other guidelines allow region-specific protocols due to sociodemographic, geographical and ethnic differences. We planned to analyze the prevalence of GBS rectovaginal carriage at 36-37 weeks gestation and its effect on early neonatal status...
October 6, 2022: Journal of Tropical Pediatrics
https://read.qxmd.com/read/36215812/ameliorating-adverse-perinatal-outcomes-with-lactoferrin-an-intriguing-chemotherapeutic-intervention
#26
REVIEW
Julie A Talbert, Jacky Lu, Sabrina K Spicer, Rebecca E Moore, Steven D Townsend, Jennifer A Gaddy
Adverse pregnancy outcomes affect 54 million people globally per year, with at least 50% of these attributed to infection during gestation. These include inflammation of the membranes surrounding the growing fetus (chorioamnionitis), preterm prelabor rupture of membranes (PPROM), preterm birth (PTB), early-onset disease (EOD) and late-onset disease (LOD), neonatal and maternal sepsis, and maternal or fetal demise. Although universal screening and implementation of intrapartum antibiotic prophylaxis (IAP) has improved EOD outcomes, these interventions have not reduced the incidences of LOD or complications occurring early on during pregnancy such as PPROM and PTB...
September 29, 2022: Bioorganic & Medicinal Chemistry
https://read.qxmd.com/read/36117423/comparison-of-obstetric-to-institutional-antibiogram-as-an-approach-to-advance-antimicrobial-stewardship-in-maternal-care
#27
JOURNAL ARTICLE
Angela R Boyd, Ariana L Lewis, Steven Dallas, Elly Xenakis, Patrick S Ramsey
OBJECTIVE: To create an antibiogram derived exclusively from our obstetric population and compare the clinical isolates and susceptibilities to our institutional antibiogram. METHODS: Data collected by the University Hospital Clinical Microbiology Laboratory in SSC Soft from 01/01/2018 to 12/31/2018 was used to generate our institutional antibiogram. For comparison, we created an obstetric (OB) antibiogram using all clinical isolates collected during the same time interval from OB triage, labor & delivery, antepartum and postpartum wards...
September 18, 2022: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/36002935/incidence-of-neonatal-sepsis-after-universal-antenatal-culture-based-screening-of-group-b-streptococcus-and-intrapartum-antibiotics-a-multicentre-retrospective-cohort-study
#28
MULTICENTER STUDY
Ying Tze Viola Chan, Steven Yuk Fai Lau, Shuk Yi Annie Hui, Teresa Ma, Choi Wah Kong, Lee Ting Kwong, Diana Chan, Diana Lee, Sau Lan Mok, Vinci Ma, Yim Chong Lo, Kwok Yin Leung, Wing Cheong Leung
OBJECTIVE: To compare the incidences of early and late-onset neonatal sepsis, including group B streptococcus (GBS) and Escherichia coli (E. coli) before and after implementation of universal screening and intrapartum antibiotics prophylaxis (IAP). DESIGN: Retrospective cohort study. SETTING: Eight public hospitals and 31 Maternal and Child Health Centres (in Hong Kong. POPULATION: 460 552 women attending routine antenatal service from 2009 to 2020...
January 2023: BJOG: An International Journal of Obstetrics and Gynaecology
https://read.qxmd.com/read/35975511/prevalence-of-group-b-streptococcus-colonization-in-pregnant-women-at-a-university-hospital-in-korea
#29
JOURNAL ARTICLE
Kyung Eun Song, Narae Hwang, Ji Yeon Ham, Hyun-Hwa Cha, Gun Oh Chong, Nan Young Lee
BACKGROUND: Group B Streptococcus (GBS) colonization in pregnant women is a risk factor for causing infection in neonates; therefore, GBS screening tests are performed on them. Culture methods and molecular diagnostics are mainly performed for GBS detection; however, culture methods differ in the detection rate for GBS depending on the procedure of culture. The authors intended to confirm the difference in GBS colonization rate in the conventional culture method, enrichment culture method, and molecular genetic test as screening tests for GBS...
August 1, 2022: Clinical Laboratory
https://read.qxmd.com/read/35693054/screening-of-group-b-streptococcus-infection-in-pregnancy-and-neonatal-outcomes-in-the-province-of-trento-italy
#30
JOURNAL ARTICLE
Silvano Piffer, Roberto Rizzello, Mariangela Pedron, Laura Dellanna, Anna Lina Lauriola
The study analyzes the trend of group B streptococcal (GBS) infection in pregnancy in the province of Trento, Italy, where a universal screening of GBS infection in pregnancy has been active for some time. Data from pregnant women who gave birth at local maternity units between 2015-2019 were obtained from birth attendance certificates (BAC), the main - and mandatory - source of information for monitoring pregnancies, births and neonatal health in Italy. The BAC used in the province of Trento acquires the results of a vast range of infections in pregnancy...
2022: Le Infezioni in Medicina
https://read.qxmd.com/read/34888893/group-b-streptococcus-real-time-pcr-may-potentially-reduce-intrapartum-maternal-antibiotic-treatment
#31
JOURNAL ARTICLE
Nir Kugelman, Shiran Kleifeld, Pninit Shaked-Mishan, Wisam Assaf, Inbal Marom, Nadav Cohen, Maya Gruber, Ofer Lavie, Dan Waisman, Reuven Kedar, Mordehai Bardicef, Amit Damti
BACKGROUND: Protocols for preventing early-onset group B streptococcal (GBS) neonatal infection may result in unnecessary antibiotics administration. Real-time polymerase chain reaction (PCR) can provide a result within 30-60 min and has been found to be specific and sensitive for defining intrapartum GBS status. OBJECTIVE: To evaluate whether implementation of GBS fast real-time PCR to all women who require GBS prophylaxis may reduce the use of maternal prophylactic antibiotics...
December 9, 2021: Paediatric and Perinatal Epidemiology
https://read.qxmd.com/read/34865875/high-rates-of-colonization-and-antimicrobial-resistance-of-group-b-streptococcus-highlight-the-need-for-vaccination-even-after-implementation-of-guidelines-for-intrapartum-antibiotic-prophylaxis
#32
JOURNAL ARTICLE
Ching-Hui Wang, Wan-Ju Kung, Chien-Hung Lee, Cheng-Fa Lee, Chia-Ling Kao, Hui-Chi Chen, Ting-Wen Hsu, Ching-Chiang Lin
INTRODUCTION: It is estimated that about 11-35% of pregnant women are colonized with Group B streptococcus. Intrapartum antibiotic prophylaxis (IAP) is the primary intervention to decrease the risk of infecting babies born to GBS colonized mothers. METHODS: A total of 5,996 pregnant women, who received the Taiwanese universal GBS screening program from 2012 to 2020, were included in this study that investigated GBS colonization, antimicrobial resistance rates and their neonatal incidence of invasive GBS infection...
December 2, 2021: Vaccine
https://read.qxmd.com/read/34784616/group-b-streptococcus-rectovaginal-colonization-and-resistance-patterns-in-hiv-positive-compared-to-hiv-negative-pregnant-patients
#33
JOURNAL ARTICLE
John A Morgan, Miriam E Hankins, Nicholas A Callais, Charles W Albritton, John A Vanchiere, Raymond E Betcher, David F Lewis
OBJECTIVE:  The objective of our study is to determine if human immunodeficiency virus (HIV)-positive pregnant patients have a higher rate of group B streptococcus (GBS) rectovaginal colonization compared with HIV-negative pregnant patients. METHODS:  Our study is a multi-site retrospective study performed at Ochsner Louisiana State University-Health Shreveport and Monroe campuses including patients who delivered between December 2011and June 2019. Rates of GBS rectovaginal colonization between HIV-positive pregnant patients were compared with a control group of HIV-negative patients...
November 16, 2021: American Journal of Perinatology
https://read.qxmd.com/read/34721327/the-s-protein-of-group-b-streptococcus-is-a-critical-virulence-determinant-that-impacts-the-cell-surface-virulome
#34
JOURNAL ARTICLE
Anaamika Campeau, Satoshi Uchiyama, Concepcion Sanchez, Consuelo Sauceda, Victor Nizet, David J Gonzalez
Group B Streptococcus (GBS, S. agalactiae ) is a human commensal and occasional pathogen that remains a leading cause of neonatal sepsis and meningitis with increasing disease burden in adult populations. Although programs for universal screening in pregnancy to guide intrapartum prophylaxis have reduced GBS invasive disease burden resulting from mother-to-newborn transfer during birth, better knowledge of disease mechanisms may elucidate new strategies to reduce antibiotic exposure. In our efforts to expand the knowledge base required for targeted anti-virulence therapies, we identified a GBS homolog for a recently identified virulence determinant of group A Streptococcus , S protein, and evaluated its role in GBS pathogenesis...
2021: Frontiers in Microbiology
https://read.qxmd.com/read/34535202/current-status-of-group-b-streptococcus-infection-in-neonates-a-multicenter-prospective-study
#35
JOURNAL ARTICLE
Yao Zhu, Lei Gao, Zhong-Ling Huang, Jia-Yin Wu, Yan Ni, Ya-Juan Wang, Tong-Zhen Ji, Jin-Zhu Wei, Chun-Xiu Zhang, Rui-Hua Ba, Fen-Fen Ou, Si-Min Ma, Ming-Yuan He, Rong Lin, Bin Peng, Xin-Zhu Lin
OBJECTIVES: To investigate the incidence of maternal group B Streptococcus (GBS) colonization and neonatal early-onset GBS disease (GBS-EOD), and to study the factors associated with the development of GBS-EOD in the offspring of pregnant women with GBS colonization. METHODS: A total of 16 384 pregnant women and 16 634 neonates delivered by them were enrolled prospectively who had medical records in Xiamen Maternal and Child Care Hospital, Beijing Obstetrics and Gynecology Hospital of Capital Medical University, and Zhangzhou Zhengxing Hospital from May 1, 2019 to April 30, 2020...
2021: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://read.qxmd.com/read/34304468/-the-bacteriological-characteristics-and-drug-resistance-of-the-nasopharyngeal-region-in-311-cases-of-adenoid-hypertrophy-with-secretory-otitis-media
#36
JOURNAL ARTICLE
Zhen Xu, Chunhua Han, Zhihong Dang, Tianqiao Huang, Zhiyuan Li, Yichuan Huang
Objective: To analyze the bacteriological distribution and drug resistance of nasopharynx in patients with adenoid hypertrophy complicated with secretory otitis media, and to clarify the distribution of pathogenic bacteria, so as to provide guidance and basis for antibiotic use in clinical treatment. Methods: A retrospective analysis was performed on 311 patients with adenoid hypertrophy and secretory otitis media who underwent surgical treatment in the department of otolaryngology head and neck surgery, Affiliated Hospital of Qingdao University from February 2013 to January 2020...
May 2021: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://read.qxmd.com/read/34217874/epidemiology-and-trends-of-infective-meningitis-in-neonates-and-infants-less-than-3-months-old-in-hong-kong
#37
JOURNAL ARTICLE
Chi Hang Wong, Jaime Rosa Duque, Joshua Sung Chih Wong, Chi-Man Victor Chan, Cheuk San Ivan Lam, Yu Ming Fu, Kai-Ning Cheong, Gilbert T Chua, Pamela P Lee, Patrick Ip, Marco Hok Kung Ho, Ian Chi Kei Wong, Godfrey Chi Fung Chan, Wing Hang Leung, So Lun Lee, Kwok Piu Lee, Chi Chiu Shek, Ming Sum Rosanna Wong, Mabel Siu Chun Wong, Yu-Lung Lau, Mike Yat-Wah Kwan
OBJECTIVES: Meningitis in neonates and young infants leads to significant morbidity and mortality worldwide. This study aimed to investigate pathogens, antibiotic resistance and secular change of incidence in Hong Kong. METHODS: A retrospective search was performed on meningitis in neonates and infants aged <3 months in three Hong Kong public hospitals from 2004 to 2019. Medical charts were reviewed, with focus on the identification and antibiotic resistance of the pathogens...
October 2021: International Journal of Infectious Diseases: IJID
https://read.qxmd.com/read/34007189/etiology-of-neonatal-bacterial-meningitis-and-their-antibiotic-susceptibility-pattern-at-the-university-of-gondar-comprehensive-specialized-hospital-ethiopia-a-seven-year-retrospective-study
#38
JOURNAL ARTICLE
Sirak Biset, Ayantu Benti, Lidya Molla, Sitot Yimer, Tena Cherkos, Yalewayker Eyayu, Ashenafi Ebabu, Desie Kasew, Aklilu Ambachew
BACKGROUND: Meningitis, which is mostly caused by infectious agents, occurs more commonly during the first month of life. Bacterial meningitis is an important source of mortality and morbidity, especially in neonates of resource-limited countries. We aimed to determine the prevalence and etiological agents of bacterial meningitis and their antibiotic susceptibility pattern in neonates at the University of Gondar Comprehensive Specialized Hospital. METHODS: We collected retrospective data from bacteriological results of cerebrospinal fluid of meningitis suspected neonates from 2013 to 2019...
2021: Infection and Drug Resistance
https://read.qxmd.com/read/33987829/intrapartum-antibiotic-prophylaxis-for-women-who-are-screened-positive-for-group-b-streptococcal-colonisation-clinical-compliance-with-the-guideline
#39
JOURNAL ARTICLE
Kathryn Braye, John Ferguson, Jean Ball, Maralyn Foureur
BACKGROUND: In high income countries, ~30% of pregnant women are provided with intrapartum antibiotic prophylaxis (IAP) for early-onset group B streptococcal infection (EOGBSI). The infection rate is low, 0.2/1000 livebirths in our jurisdiction, and others. We hypothesised factors, other than IAP alone, were reasons for the low rate of EOGBSI. AIMS: Compliance with our local guideline, referred to here as 'the guideline'. METHOD: Compliance was defined as an initial dose of benzylpenicillin IAP followed by four-hourly doses until birth...
December 2021: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://read.qxmd.com/read/33911829/group-b-streptococcus-recto-vaginal-colonization-in-near-term-pregnant-women-southwest-ethiopia
#40
JOURNAL ARTICLE
Woubishet Girma, Nadia Yimer, Tesfaye Kassa, Elias Yesuf
Background: Group B Streptococcus (GBS) is recognized as an important cause of maternal and neonatal morbidity and mortality. Maternal vaginal carriage of GBS (Streptococcus agalactiae) can lead to vertical transmission to the neonate at the time of delivery. However, little is known about its prevalence, predictors and antibiotic susceptibility pattern in Jimma, Ethiopia. This study assessed the prevalence, antimicrobial susceptibility pattern and determinants of GBS recto-vaginal colonization among near-term pregnant women...
September 2020: Ethiopian Journal of Health Sciences
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