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obstructive uropathy

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https://www.readbyqxmd.com/read/28062436/contralateral-inguinal-herniation-of-a-transplant-ureter-causing-obstructive-uropathy-in-a-renal-transplant-recipient
#1
Niyati Lobo, Fiona McCaig, Jonathon Olsburgh
Ipsilateral inguinal herniation of the transplanted ureter has been reported as a rare cause of obstructive uropathy in renal transplant recipients. A 73-year-old man presented with acute renal failure 29 years after receiving a deceased donor renal transplant. Radiological investigations demonstrated marked hydronephrosis of the left iliac fossa transplant kidney and herniation of the distal transplant ureter and bladder into the right inguinal canal. The patient underwent placement of a nephrostomy and antegrade stent followed by definitive hernia repair with return of graft function to baseline level...
January 6, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28012005/primary-non-surgical-management-of-unilateral-ureteropelvic-junction-obstruction-in-children-a-systematic-review
#2
REVIEW
Marcus Weitz, Maria Schmidt, Guido Laube
Ureteropelvic junction obstruction (UPJO) is the most common obstructive uropathy and its optimal management remains controversial. However, there is a current trend towards non-surgical management. We aimed to determine the effects of the non-surgical management in children with unilateral UPJO. For a systematic review, we searched MEDLINE, EMBASE, CENTRAL, clinical trials registries, and selected conference proceedings for eligible studies. Any type of study reporting the outcomes renal function, secondary surgical intervention, drainage pattern or hydronephrosis of non-surgical management in children with unilateral UPJO was included...
December 23, 2016: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28011273/obstructive-nephropathy-without-hydronephrosis-suspicion-is-the-key
#3
Don H Esprit, Abhilash Koratala, Volodymyr Chornyy, Charles Wingo
Urinary tract obstruction leading to acute kidney injury is usually associated with bilateral hydroureters and hydronephrosis, often accompanied by oliguria. We present an atypical case of obstructive uropathy without these features that presented with severe acute kidney injury. A 64-year-old male with no known past medical history has presented with a 2-week history of nausea, decreased appetite, flank pain, lower extremity edema and was found to have elevated creatinine of 10.5 mg/dL. Renal ultrasound showed mild prominence of the bilateral renal collecting systems with no evidence of hydronephrosis...
December 20, 2016: Urology
https://www.readbyqxmd.com/read/28010137/hydronephrosis-with-ureteritis-developed-in-c57bl-6n-mice-carrying-the-congenic-region-derived-from-mrl-mpj-type-chromosome-11
#4
Osamu Ichii, Masataka Chihara, Shin-Hyo Lee, Teppei Nakamura, Saori Otsuka-Kanazawa, Taro Horino, Yaser Hosny Ali Elewa, Yasuhiro Kon
Inbred MRL/MpJ mice show several unique phenotypes in tissue regeneration processes and the urogenital and immune systems. Clarifying the genetic and molecular bases of these phenotypes requires the analysis of their genetic susceptibility locus. Herein, hydronephrosis development was incidentally observed in MRL/MpJ-derived chromosome 11 (D11Mit21-212)-carrying C57BL/6N-based congenic mice, which developed bilateral or unilateral hydronephrosis in both males and females with 23.5% and 12.5% prevalence, respectively...
December 23, 2016: Autoimmunity
https://www.readbyqxmd.com/read/28001177/uromodulin-a-new-biomarker-of-fetal-renal-function
#5
Thais Emanuelle Faria Botelho, Alamanda Kfoury Pereira, Patrícia Gonçalves Teixeira, Eura Martins Lage, Gabriel Costa Osanan, Ana Cristina Simões E Silva
INTRODUCTION: Obstructive uropathies are main diseases affecting the fetus. Early diagnosis allows to establish the appropriate therapy to minimize the risk of damage to kidney function at birth. Biochemical markers have been used to predict the prognosis of renal function in fetuses. Uromodulin, also known by Tamm-Horsfall protein (THP) is exclusively produced in the kidneys and in normal conditions is the protein excreted in larger amounts in human urine. It plays important roles in kidneys and urinary tract...
December 2016: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/27951542/critical-analysis-of-a-series-of-early-inguinal-ureterostomies-are-they-useful-and-how-well-are-they-tolerated
#6
Aurore Bouty, Yan Lefevre, Luke Harper, Antoine Tran, Pierre Vergnes, Eric Dobremez
INTRODUCTION: The study aimed to evaluate the advantages of temporary inguinal ureterostomy in the management of neonates with uropathies and early or recurrent pyelonephritis. PATIENTS AND METHODS: We performed a retrospective analysis of all patients who underwent ureterostomies between 1989 and 2012, with specific regards to indications and outcomes. We also performed a survey of parents to evaluate their acceptance of diversion. RESULTS: We included 18 patients (12 primary high-grade vesicoureteral reflux [VUR] and 6 primary obstructive megaureters [MUs])...
December 13, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27909624/for-reliable-urine-cultures-in-the-detection-of-complicated-urinary-tract-infection-do-we-use-urine-specimens-obtained-with-urethral-catheter-or-a-nephrostomy-tube
#7
Gülay Dede, Özcan Deveci, Onur Dede, Mazhar Utanğac, Mansur Dağgulli, Necmettin Penbegül, Namık Kemal Hatipoğlu
OBJECTIVE: The aim of this study was to compare the results of urine cultures obtained either from urethral, and percutaneous nephrostomy (PCN) catheters. MATERIALS AND METHODS: This study included 328 consecutive patients that underwent PCN at our institution with complicated urinary tract infections (UTIs) between July 2010 and April 2015. Results of urine cultures obtained from the urethral and nephrostomy catheters were compared. RESULTS: This study included 152 male and 176 female patients...
December 2016: Turkish Journal of Urology
https://www.readbyqxmd.com/read/27904827/presentation-of-idiopathic-retroperitoneal-fibrosis-at-a-young-age-a-rare-case-report
#8
Priyanka Minocha, Ankur Setia
Abdominal pain is a very common symptom in all age groups but retroperitoneal fibrosis is a rare differential diagnosis suspected in young patients presenting with nonspecific abdominal pain and symptoms of obstructive uropathy. Presented here is a case of a 16-year-old boy who presented with symptoms of persistent abdominal pain and a previous history of swelling in the left leg. A computed tomography (CT) scan suggested retroperitoneal fibrosis and an exploratory laparotomy and histopathological examination were performed for definitive diagnosis...
November 2016: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/27888411/to-screen-or-not-to-screen-for-vesicoureteral-reflux-in-children-with-ureteropelvic-junction-obstruction-a-systematic-review
#9
REVIEW
Marcus Weitz, Maria Schmidt
: Ureteropelvic junction obstruction (UPJO) and vesicoureteral reflux (VUR) are the most common uropathies. The co-occurrence of both anomalies has led to the practice of screening for VUR in children with UPJO to prevent deterioration of kidney function due to renal scarring following urinary tract infections (UTIs). We determined the prevalence of VUR in children with UPJO for a critical assessment of VUR screening by voiding cystourethrography (VCUG). A systematic search strategy in MEDLINE, EMBASE, and CENTRAL was carried out for all articles that included VCUG, and renal scintigraphy or any other appropriate imaging technique for the diagnosis of UPJO...
January 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/27876076/bladder-outlet-obstruction-a-rare-complication-of-the-neglected-schistosome-schistosoma-haematobium-two-case-reports-and-public-health-challenges
#10
Valirie Ndip Agbor, Tsi Njim, Franklin Ngu Mbolingong
BACKGROUND: Schistosomiasis is a severe parasitic infestation with debilitating complications and is the third most devastating tropical disease in the world. It is one of the neglected tropical diseases (NTDs) with a high disease-burden. We present two rare cases of bladder outlet obstruction: one which led to a chronic kidney disease and ultimately death and a second which recovered after treatment with praziquantel. CASE PRESENTATIONS: A 72 year old male presented with lower urinary tract symptoms which culminated in an episode of acute urinary retention...
November 22, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27861745/clinical-signs-of-fibrosis-in-small-intestinal-neuroendocrine-tumours
#11
K Daskalakis, A Karakatsanis, P Stålberg, O Norlén, P Hellman
BACKGROUND: In patients with small intestinal neuroendocrine tumours (SI-NETs), serotonin and other cytokines released from tumour cells may induce fibrosis, leading to carcinoid heart disease and abdominal fibrotic reactions. The aim of this study was to assess the prevalence, clinical complications and management of this reaction in the abdomen. METHODS: This was a retrospective cohort study of patients with SI-NETs diagnosed between 1985 and 2015. Clinical data, outcomes, radiological findings, and surgical and radiological interventions were reviewed...
January 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/27852120/kim-1-is-a-potential-urinary-biomarker-of-obstruction-results-from-a-prospective-cohort-study
#12
Daniel Olvera-Posada, Thamara Dayarathna, Marie Dion, Husain Alenezi, Alp Sener, John D Denstedt, Stephen E Pautler, Hassan Razvi
INTRODUCTION: Partial or complete obstruction of the urinary tract is a common and challenging urological condition that may occur in patients of any age. Serum creatinine is the most commonly used method to evaluate global renal function, although it has low sensitivity for early changes in the glomerular filtration rate or unilateral renal pathology. Hence, finding another measurable parameter that reflects the adaptation of the renal physiology to these circumstances is important. Several recent studies have assessed the use of new biomarkers of acute kidney injury (AKI), but the information among patients with stone disease and those with obstructive uropathy is limited...
December 19, 2016: Journal of Endourology
https://www.readbyqxmd.com/read/27846034/an-update-on-classification-and-management-of-urosepsis
#13
Florian M E Wagenlehner, Zafer Tandogdu, Truls E Bjerklund Johansen
PURPOSE OF REVIEW: The urinary tract is the infection site in severe sepsis/septic shock in 10-30%. RECENT FINDINGS: There is a new Sepsis definition focusing on severe sepsis. Urosepsis is mainly due to obstructed uropathy of the upper urinary tract. The pathogenesis of sepsis is complex and is driven by the innate immune system. In the further course immunosuppression is developing.Management of urosepsis includes early diagnosis, early initiation of treatment such as identification and control of the complicating factor in the urinary tract and the specific sepsis therapy...
November 14, 2016: Current Opinion in Urology
https://www.readbyqxmd.com/read/27818827/obstructive-uropathy-secondary-to-missed-acute-appendicitis
#14
Mahir Gachabayov
Hydronephrosis is a rare complication of acute appendicitis. We present a case of missed appendicitis in a 52-year-old female which presented as a right-sided hydronephrosis. 2 days after admission to the Department of Urology CT revealed acute appendicitis for what open appendectomy was performed. Acute appendicitis can lead to obstructive uropathy by periappendiceal inflammation due to adjacency. Urologists, surgeons, and emergency physicians should be aware of this rare complication of atypical acute appendicitis...
2016: Case Reports in Surgery
https://www.readbyqxmd.com/read/27785626/neutrophil-gelatinase-associated-lipocalin-utility-in-urologic-conditions
#15
EDITORIAL
Catherine S Forster, Prasad Devarajan
Neutrophil gelatinase-associated lipocalin (NGAL) is best known as a non-invasive early marker of acute kidney injury (AKI). However, recent published reports have described additional utility of both plasma NGAL (pNGAL) and urine NGAL (uNGAL) in various pathologic conditions within the pediatric urinary tract, including urinary tract infection, vesicoureteral reflux (VUR), renal scarring, and obstructive uropathy. These two forms of NGAL have different applications related to their mechanisms of upregulation: pNGAL can serve as a marker of systemic inflammatory conditions, whereas uNGAL is specific for insults to the renal epithelium...
October 26, 2016: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/27766283/term-neonate-with-liver-laceration-obstructive-uropathy-and-ascites-secondary-to-extravasation-of-total-parenteral-nutrition-a-complication-of-malpositioned-umbilical-venous-catheter
#16
Olubukunola Adesanya, Mubariz Naqvi
We report a rare, but serious, complication of a malpositioned umbilical venous catheter in a term male infant who developed laceration, hematoma, and necrosis of liver, ascites, and left-sided obstructive uropathy secondary to extravasation of total parenteral nutrition. Abdominal paracentesis confirmed the presence of parenteral nutrition in the peritoneal cavity. Although, the umbilical venous catheterization is a common intravenous access used in neonatal intensive care units, judicious continued monitoring of its use should be practiced to avoid serious complications...
2016: Global Pediatric Health
https://www.readbyqxmd.com/read/27764886/-female-preterm-monozygotic-twins-discordant-for-fetal-megacystis-due-to-cloacal-dysgenesis-after-conception-by-intracytoplasmatic-sperm-injection-case-report-and-review-of-literature
#17
M Schneider, I Schmeh, A Fruth, C Whybra-Trümpler, E Mildenberger
Monozygotic twins were previously regarded as "identical". By now an increasing number of case reports of monozygotic but discordant twins have been reported, and therefore discordance between monozygotic twins is being investigated intensively. We report a case of female preterm monozygotic twins who were discordant for fetal megacystis due to cloacal dysgenesis. Pregnancy was achieved after intracytoplasmatic sperm injection and transfer of 2 embryos. By the first trimester fetal megacystis with consecutive oligohydramnios and hypoplasia of the lungs was diagnosed...
October 2016: Zeitschrift Für Geburtshilfe und Neonatologie
https://www.readbyqxmd.com/read/27725322/-indications-and-morbidity-associated-with-double-j-catheters
#18
M Cepeda, J A Mainez, B de la Cruz, J H Amón
The use of double J catheters is usual in urologist's daily practice. The indication can be divided in prophylactic or therapeutic. Prophylactically, they prevent complications derived from endourological procedures, such as ureteral lesion or obstructive uropathy secondary to residual lithiasis or edema. Therapeutically, they treat obstructive uropathy of many different pathologies, either in an emergency setting or scheduled, such as lithiasis, stenosis, extrinsic compression of any nature or urinary tract tumors among others...
October 2016: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/27704057/sulfadiazine-induced-obstructive-nephropathy-presenting-with-upper-urinary-tract-extravasation
#19
Maharan Kabha, Snir Dekalo, Sophie Barnes, Ishay Mintz, Haim Matzkin, Mario Sofer
Background: Obstructive nephropathy is an uncommon side effect of sulfadiazine, which is used for the treatment of toxoplasmosis. We present a case of acute renal colic and urine extravasation of a patient shortly after she was started on this medication. Case Presentation: A 31-year-old female presented with acute renal colic 2 weeks after starting treatment with sulfadiazine and pyrimethamine for ocular toxoplasmosis. Results: A noncontrast computed tomography revealed left hydronephrosis and fluid located around the kidney and in the left gutter...
2016: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/27695182/management-of-a-renal-fungal-bezoar-caused-by-multidrug-resistant-candida-glabrata
#20
Gemma A Berlanga, Graham L Machen, Patrick S Lowry, Karen B Brust
We describe our management of an immunocompetent individual who developed obstructive uropathy and candidemia as a result of a fungal bezoar in the kidney. These sequelae arose from candiduria, provoked after several courses of antibiotics. Successful treatment included therapy with both culture-appropriate intravenous antifungals and operative intervention, including direct irrigation of the affected kidney with amphotericin B, relief of renal obstruction with a ureteral stent, a percutaneous nephrostomy tube, and ultimately endoscopic removal of the fungal bezoar...
October 2016: Proceedings of the Baylor University Medical Center
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