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obstructive uropathy

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https://www.readbyqxmd.com/read/29782632/prevalence-of-clinically-validated-primary-causes-of-end-stage-renal-disease-esrd-in-a-state-capital-in-northeastern-brazil
#1
Luana Rodrigues Sarmento, Paula Frassinetti Castelo Branco Camurça Fernandes, Marcelo Ximenes Pontes, Daniel Barros Santos Correia, Victhor Castelo Branco Chaves, Cecília Ferreira de Araújo Carvalho, Tiago Lima Arnaud, Matheus Henrique Seixas Dos Santos, Livia Cristina Barros Barreto, Larissa Alves Alexandre Moliterno
INTRODUCTION: Knowledge of validated primary causes of end-stage renal disease (ESRD) is extremely relevant in the realm of public health. The literature lacks validated studies on the primary causes of ESRD. OBJECTIVE: The aim of this study was to estimate the prevalence of the causes of ESRD in a State Capital in Northeastern Brazil. METHODS: This cross-sectional study was based on the analysis of medical records of patients on hemodialysis at five specialized centers in Fortaleza, CE, Brazil...
May 17, 2018: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/29778493/retrograde-ureteral-catheterization-a-possible-new-treatment-for-renal-fungal-balls-in-very-low-birth-weight-infants
#2
Cheng-Wei Chen, Chyong-Hsin Hsu, Jin-Cherng Sheu, Hsin Chi, Jui-Hsing Chang, Chun-Chen Lin, Jeng-Daw Tsai
Invasive candidiasis is a serious pathogen of late-onset sepsis in very-low-birth- weight (VLBW) infants. Kidney is the most common organ involved and it causes morbidity and mortality, especially when fungal balls are formed. We report a 34-day-old female infant (28 weeks, 1152 gm) with systemic fungal infection complicated obstructive uropathy. On sonography, the fungal balls filled the entire pelvis without hydronephrosis. Percutaneous nephrostomy was not feasible. In addition to systemic antifungals, we successfully performed cystoscopy-assisted retrograde ureteral catheterization (RUC) to decompress the pelvis, which also provided a route for local amphotericin B irrigation to achieve therapeutic concentration without nephrotoxicity...
May 17, 2018: Urology
https://www.readbyqxmd.com/read/29706289/urinary-antimicrobial-peptides-potential-novel-biomarkers-of-obstructive-uropathy
#3
S Gupta, A R Jackson, D G DaJusta, D J McLeod, S A Alpert, V R Jayanthi, K McHugh, A R Schwaderer, B Becknell, C B Ching
INTRODUCTION: Antimicrobial peptides (AMPs) have historically been evaluated for their role in protecting against uropathogens. However, there is mounting evidence to support their expression in noninfectious injury, with unclear meaning as to their function. It is possible that AMPs represent urothelial injury. Urinary tract obstruction is known to alter the urothelium; however, AMPs have not been evaluated for expression in this noninfectious injury. OBJECTIVE: A pilot study to compare urinary AMP expression in children undergoing surgical intervention for ureteropelvic junction obstruction (UPJO) with nonobstructed controls...
March 29, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29657211/etiological-profile-of-chronic-kidney-disease-a-single-center-retrospective-hospital-based-study
#4
Manjuri Sharma, Prodip Doley, Himanab Jyoti Das
Chronic kidney disease (CKD) is one of the leading causes of chronic diseases globally, with rising incidence and prevalence. It is a major risk factor for cerebrovascular disease and coronary artery disease, which are the main causes of death in this population. The etiology of CKD is varied. This study was performed to evaluate the various etiologies of CKD among patients presenting to the Department of Nephrology, Guwahati Medical College, a tertiary referral center. A total of 5718 CKD patients were evaluated to identify the cause of CKD...
March 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29644043/inguinal-hernia-causing-extrinsic-compression-of-bilateral-ureters-leading-to-chronic-obstructive-uropathy
#5
Peter T Grice, Nkwam Nkwam
Ureteral inguinal hernias are a well-documented cause of obstructive uropathy with ureteric involvement in the hernia sac. In this unique case, the left-sided inguinal hernia causes extrinsic compression of bilateral ureters outside of the hernia sac leading to chronic obstructive uropathy, which is demonstrated on non-contrast CT and cystogram. This patient was managed with nephrostomy and subsequently antegrade stenting with nephrostomy removal. Prior to nephrostomy removal, nephrostogram demonstrated tapering of the left ureter in the pelvis...
April 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29629062/clinical-outcomes-of-the-simultaneous-bilateral-percutaneous-nephrolithotomy-pcnl-in-patients-with-kidney-stones-a-prospective-cohort-study
#6
Mohammad Reza Darabi, Salman Soltani, Alireza Akhavan Rezayat, Masoud Yousefi, Mehdi Kashefi, Mahmoud Tavakkoli, Shabnam Mohammadi
Background: Urinary tract stones is one of the most frequent medical emergencies which leads to life-threatening complications, namely obstructive uropathy as well as renal failure in some situations. Previously, bilateral stones were treated with either open surgery or percutaneous nephrolithotomy (PCNL). However, these treatment options were associated with lengthy operation time, need for more anesthesia, further bleeding, and long hospitalization. Therefore, much effort has been made to treat both sides simultaneously...
February 2018: Electronic Physician
https://www.readbyqxmd.com/read/29621498/urinary-ascites-secondary-to-bilateral-mid-ureteral-stenosis-in-a-neonate
#7
Fumi Matsumoto, Masataka Kawamura, Futoshi Matsui, Koji Yazawa, Kenji Shimada
Urinary ascites is most commonly seen in fetuses and newborns with obstructive uropathy. The majority of cases are associated with lower urinary tract obstruction, such as posterior urethral valves. In this report, we present a unique case of neonatal urinary ascites caused by congenital supravesical obstruction. To date, neonatal urinary ascites secondary to bilateral mid-ureteral stenosis without a history of antenatal diagnosis has not been reported.
April 2, 2018: Urology
https://www.readbyqxmd.com/read/29541493/necrotizing-fasciitis-of-thoracic-and-abdominal-wall-with-emphysematous-pyelonephritis-and-retroperitoneal-abscess
#8
Sanjay Mhalasakant Khaladkar, Kunaal Mahesh Jain, Rajesh Kuber, Sidappa Gandage
Emphysematous pyelonephritis is a life-threatening severe form of pyelonephritis usually occurring in patients with diabetes mellitus with or without obstructive uropathies in whom there is necrotizing infection leading to the gas production of an unclear mechanism involving the renal parenchyma and the collecting system. Necrotizing fasciitis is characterized by progressive necrosis of fat and fascia due to deep-seated infection of subcutaneous tissue. It has a fulminant course with considerable mortality...
2018: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/29534877/the-protective-arm-of-the-renin-angiotensin-system-may-counteract-the-intense-inflammatory-process-in-fetuses-with-posterior-urethral-valves
#9
Natalia P Rocha, Fernando M Bastos, Érica L M Vieira, Thiago R R Prestes, Katia D da Silveira, Mauro M Teixeira, Ana Cristina Simões E Silva
OBJECTIVE: Posterior urethral valve is the most common lower urinary tract obstruction in male children. A high percentage of patients with posterior urethral valve evolve to end-stage renal disease. Previous studies showed that cytokines, chemokines, and components of the renin-angiotensin system contribute to the renal damage in obstructive uropathies. The authors recently found that urine samples from fetuses with posterior urethral valve have increased levels of inflammatory molecules...
March 11, 2018: Jornal de Pediatria
https://www.readbyqxmd.com/read/29522906/daily-therapy-with-a-slow-releasing-h-2-s-donor-gyy4137-enables-early-functional-recovery-and-ameliorates-renal-injury-associated-with-urinary-obstruction
#10
Shouzhe Lin, Dameng Lian, Weihua Liu, Aaron Haig, Ian Lobb, Ahmed Hijazi, Hassan Razvi, Jeremy Burton, Matthew Whiteman, Alp Sener
OBJECTIVES: To assess the effects of slow-releasing H2 S donor GYY4137 on post-obstructive renal function and injury following unilateral ureteral obstruction (UUO) by using the UUO and reimplantation (UUO-R) model in rats and to elucidate potential mechanisms by using an in vitro model of epithelial-mesenchymal transition (EMT). METHODS: Male Lewis rats underwent UUO at the left ureterovesical junction. From post-operative day (POD) 1-13, rats received daily intraperitoneal (IP) injection of phosphate buffered saline (PBS, 1 mL) or GYY4137 (200 μmol/kg/day in 1 mL PBS, IP)...
June 1, 2018: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/29501311/anatomical-variations-of-the-thymus-in-relation-to-the-left-brachiocephalic-vein-findings-of-necropsia
#11
Oscar Alonso Plaza, Freddy Moreno
Two cases of anatomical variations of the thymus are presented with respect to the anatomical relations with the left brachiocephalic vein and found during the necropsy process. Less than 2 days after birth with Noonan Syndrome, when the left brachiocephalic vein was scanning behind the upper thymus horns, there were other adjacent lesions consisting of three supernumerary spleens and three hepatic veins. The second case was an 8-year-old infant with child malpractice who died from urinary sepsis due to obstructive uropathy, in which case the upper lobes of the thymus were fused and formed a ring through which the left brachiocephalic vein passed...
April 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29499256/resolution-of-diabetes-insipidus-after-pyeloplasty-a-case-report-and-review-of-the-literature
#12
Christina P Carpenter, Ashley Rawson, David S Hains, Dana W Giel
Nephrogenic diabetes insipidus (NDI), a rare cause of polyuria and polydipsia in children, is usually managed with medications and careful monitoring of water intake. We present a child who was incidentally found to have right hydronephrosis secondary to ureteropelvic junction obstruction, and was subsequently also diagnosed with NDI. After being medically managed, he underwent open right pyeloplasty. His polydipsia abated within 1 month of surgery, and he has done well off of medications since that time. NDI resolution after correction of obstructive uropathy in adults has been reported, but this represents a novel case in pediatrics...
February 28, 2018: Urology
https://www.readbyqxmd.com/read/29487099/obstructive-uropathy-from-complete-bladder-and-bilateral-ureteral-incarceration-within-an-inguinal-hernia
#13
Leah H Hellerstein, Stuart Marshall Sacks, Daniel K Hellerstein
A 59-year-old man with a medical history of hypertension, gout and obesity presented to the hospital with a chief complaint of worsening scrotal oedema. The patient endorsed associated symptoms of decreased force of stream on urination, stranguria and hesitancy with slight dysuria. Physical exam showed an effaced umbilicus and phallus with a hidden scrotum estimated to be 30×20×30 cm in size. Imaging and lab findings led to a diagnosis of total bladder herniation within an incarcerated right inguinal hernia...
February 27, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29473379/a-rare-cause-of-acute-post-renal-failure-retroperitoneal-fibrosis
#14
Kamil Gokhan Seker, Mithat Eksi, Yunus Colakoglu, Mustafa Gürkan Yenice, Fatih Gokhan Akbay, Volkan Tugcu, Abdulmuttalip Simsek
Retroperitoneal fibrosis is an inflammatory process which may cause acute renal failure. In patients who admitted to emergency services with obstructive uropathy, retroperitoneal fibrosis should be considered in the differential diagnosis. We present our ten cases who admitted to emergency department with obstructive acute renal failure related to retroperitoneal fibrosis.
December 31, 2017: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/29441752/bilateral-obstructive-uropathy-caused-by-congenital-bladder-diverticulum-presenting-as-hypertensive-retinopathy
#15
San Kim, Sang Hoo Park, Dong Yoon Kim, Seok Joong Yun, Ok Jun Lee, Heon Seok Han
A congenital bladder diverticulum (CBD) is caused by inherent muscular weakness instead of obstruction of the bladder outlet. The major clinical conditions are recurrent urinary tract infection (UTI) and voiding dysfunction. This report describes a 15-year-old male adolescent who developed sudden visual disturbance resulting from hypertensive retinopathy. The cause of hypertension was bilateral obstructive uropathy caused by enlarged paraureteral bladder diverticula. After the non-functioning right kidney and ureter and the bilateral diverticula were removed, the left ureter was reimplanted in the bladder...
February 19, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29434183/plasmacytoid-urothelial-carcinoma-of-ureter-with-retroperitoneal-metastasis-a-case-report
#16
Alexis Jibril, Andrew C Stevens
BACKGROUND Plasmacytoid is a rare histological variant of urothelial carcinoma (UC). Since the first reported case of plasmacytoid urothelial carcinoma (PUC), in 1991, only about 100 cases have since been reported, with most cases involving the bladder. Urothelial carcinomas of the upper urinary tract represent only 5% of urothelial cancers. To the best of our knowledge, there has only been 1 reported case of PUC of the ureter. PUC is a highly aggressive disease, with a poor prognosis. We present a rare biopsy-proven case of PUC of the ureter with retroperitoneal metastasis...
February 13, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29399012/value-of-magnetic-resonance-urography-versus-computerized-tomography-urography-ctu-in-evaluation-of-obstructive-uropathy-an-observational-study
#17
Saeed M Bafaraj
Background: Obstructive uropathy is a common public health issue that requires imaging research for providing necessary information. The data is important for determining treatment options, and may influence selective management choices. Objective: The aim of the study is to determine whether magnetic resonance urography or computerized tomography urography is the best imaging modality among patients with suspected obstructive uropathy. Methods: Seventy patients; referred from the emergency department for the evaluation of renal colic or hematuria that highly suggested urinary tract abnormalities, were prospectively enrolled...
February 2018: Current Medical Imaging Reviews
https://www.readbyqxmd.com/read/29390441/left-renal-failure-caused-by-chronic-obstructive-uropathy-due-to-a-uretero-inguinal-hernia-combined-with-contralateral-renal-pelvic-carcinoma-a-case-report
#18
Weiling Xu, Fangchao Gong, Dong Dong, Baorong Chi, Jingyu Wang
RATIONALE: Although rare, cases of renal failure secondary to a uretero-inguinal hernia have been reported. PATIENT CONCERNS: Here, we report a case of left renal failure caused by chronic obstructive uropathy due to a uretero-inguinal hernia combined with contralateral renal pelvic carcinoma. DIAGNOSES: The present case highly indicated that a comprehensive examination is very important when diagnosing an inguinal hernia. In particular, it is necessary to check whether the ureter is involved or not...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29388172/-a-rare-cause-of-perinatal-postrenal-failure-with-megalourethra
#19
Christine Nagel, Barbara Wiewrodt, Clemens Wirth, Gerd Ohnheiser, Johannes Wirbelauer
We present a case of a premature infant with a presumed obstructive uropathy found to be a megalourethra leading to a perinatal postrenal failure. A megalourethra - an uncommon cause of urethral dilatation - is a congenital, non-obstructive anomaly of the penile erectile tissue. We think that a distal stenosis resulted in dysplasia of the penile tissue and an aspect of a megalourethra. Further diagnostic workup included urinary tract sonograms, a voiding cystourethrogram and MAG3 scintigrafy. Initially the patient was managed with supportive care such as a suprapubic urinary catheter, followed by surgical intervention (Bengt Johanson)...
January 31, 2018: Zeitschrift Für Geburtshilfe und Neonatologie
https://www.readbyqxmd.com/read/29385997/proteinuric-kidney-disease-in-children-at-queen-elizabeth-central-hospital-malawi
#20
Zondiwe Victor Mwanza, Mignon McCulloch, Mark Drayson, Timothy Plant, David V Milford, Gavin Dreyer
BACKGROUND: There is a paucity of data on paediatric kidney disease in developing countries such as Malawi. Descriptive research on kidney disease is essential to improving patient outcomes. METHODS: We conducted a cross-sectional study at a tertiary hospital in Malawi from 2012 to 2013. Children under 14 years with proteinuric kidney disease were enrolled from paediatric wards and outpatient clinics at Queen Elizabeth Central Hospital (QECH). Demographic, clinical and laboratory data were collected from patients at enrolment and at 3 months review at which point clinical status and disease outcome were ascertained...
January 31, 2018: BMC Nephrology
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