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https://www.readbyqxmd.com/read/28535286/invited-commentary-is-strenuous-activity-good-for-you-the-legacy-of-ralph-paffenbarger
#1
Lewis H Kuller
Ralph Paffenbarger, Jr, MD, DrPH (1922-2007), was initially trained as an infectious disease epidemiologist at the Johns Hopkins School of Hygiene and Public Health (now the Bloomberg School of Public Health). He was the first Epidemiology Intelligence Service officer in the first Epidemiology Intelligence Service class. He joined the National Heart Institute (now the National Heart, Lung, and Blood Institute) in its very early days and later became a faculty member at Stanford University and Harvard University...
May 23, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28535109/intranasal-steroid-use-for-otitis-media-with-effusion-ongoing-opportunities-for-quality-improvement
#2
David E Wang, Derek J Lam, Angela M Bellmunt, Richard M Rosenfeld, Allison K Ikeda, Jennifer J Shin
Objectives Our objectives were (1) to assess patterns of intranasal steroid administration when otitis media with effusion (OME) has been diagnosed in children, (2) to investigate whether usage varies according to visit setting, and (3) to determine if practice gaps are such that quality improvement could be tracked. Study Design Cross-sectional analysis of an administrative database. Subjects and Methods National Ambulatory and Hospital Ambulatory Medical Care Surveys, 2005 to 2012; univariate, multivariate, and stratified analyses of intranasal steroid usage were performed...
May 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28535099/do-sideline-concussion-assessments-predict-subsequent-neurocognitive-impairment-after-sport-related-concussion
#3
Alicia Sufrinko, Jamie McAllister-Deitrick, Melissa Womble, Anthony Kontos
CONTEXT:   Comprehensive, multi-domain assessment is the standard of care after sport-related concussion. However, the relationship between performance on sideline concussion-assessment tools and in-office computerized neurocognitive testing has received little attention, and the prognostic utility of sideline measures is unknown. OBJECTIVE:   To evaluate concurrent impairment on commonly used concussion measures 24 to 48 hours postinjury while also determining the predictive utility of sideline measures on computerized neurocognitive testing in the acute to subacute recovery periods postinjury...
May 23, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28534434/effects-of-a-statewide-tobacco-cessation-program-among-individuals-involved-with-arkansas-community-correction
#4
Christine Garver-Apgar, Susan Young, Brenda Howard, Ben Udochi, Chad Morris
In response to a critical need for tobacco cessation services among justice-involved populations, Arkansas Community Correction (ACC) partnered with the University of Colorado's Behavioral Health & Wellness Program in 2013 to implement the DIMENSIONS: Tobacco Free Program within all probation, parole, and drug court units. In the first 2 years of this statewide, evidence-based program, more than 1,100 individuals from 33 ACC area office locations attended tobacco-free group sessions and provided data on tobacco use and readiness to quit...
January 1, 2017: Journal of Correctional Health Care
https://www.readbyqxmd.com/read/28533037/epidemiology-of-live-born-infants-with-nonimmune-hydrops-fetalis-insights-from-a-population-based-dataset
#5
Martina A Steurer, Shabnam Peyvandi, Rebecca J Baer, Tippi MacKenzie, Ben C Li, Mary E Norton, Laura L Jelliffe-Pawlowski, Anita J Moon-Grady
OBJECTIVE: To evaluate the incidence, etiology, and 1-year mortality of nonimmune hydrops fetalis (NIHF) and to identify risk factors for mortality in a contemporary population-based dataset. STUDY DESIGN: The California Office of Statewide Health Planning and Development maintains a database linking maternal and infant hospital discharge, readmissions, and birth and death certificate date from 1 year before to 1 year after birth. We searched the database (2005-2012) for infants with NIHF (identified by the International Classification of Diseases, 9th Revision, Clinical Modification code)...
May 19, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28532918/subarachnoid-haemorrhage-in-germany-between-2010-2013-estimated-incidence-rates-based-on-a-nationwide-hospital-discharge-registry
#6
Jasper H van Lieshout, Igor Fischer, Marcel A Kamp, A R T Donders, Jan F Cornelius, Hans-Jakob Steiger, Hieronymus D Boogaarts, Athanasios K Petridis
BACKGROUND: Nordic countries are the primary source for nationwide data on the incidence of subarachnoid haemorrhage (SAH). Reliable estimates of national incidence rates of SAH in other countries are lacking, yet studies from Nordic countries with exceptional incidence rate are sometimes disregarded because of concerns regarding external validity. Autopsies are rarely performed for sudden deaths, therefore estimates of the SAH incidence commonly reflect the hospital discharge rates. Our aim was to estimate the nationwide incidence of non-traumatic SAH in Germany using a national hospital discharge register...
May 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28532479/education-and-employment-in-patients-with-juvenile-idiopathic-arthritis-a-standardized-comparison-to-the-german-general-population
#7
Jenny Schlichtiger, Johannes-Peter Haas, Swaantje Barth, Betty Bisdorff, Lisa Hager, Hartmut Michels, Boris Hügle, Katja Radon
BACKGROUND: Although several studies show that JIA-patients have significantly lower employment rates than the general population, the research on educational and occupational attainments in patients with juvenile idiopathic arthritis (JIA) remain conflicting most likely due to small sample sizes. Therefore, aim of this study is to compare the educational achievements and employment status of 3698 JIA-patients with the German general population (GGP). METHODS: "SEPIA" was a large cross-sectional study on the current status of a historic cohort of JIA-patients treated in a single center between 1952 and 2010...
May 22, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28532202/experiences-of-establishing-an-academic-early-phase-clinical-trials-unit
#8
Sarah R Brown, Debbie Sherratt, Gill Booth, Julia Brown, Fiona Collinson, Walter Gregory, Louise Flanagan
BACKGROUND: Early phase trials are essential in drug development, determining appropriate dose levels and assessing preliminary activity. These trials are undertaken by industry and academia, with increasing collaborations between the two. There is pressure to perform these trials quickly, safely, and robustly. However, there are inherent differences between developing and managing early phase, compared to late phase, drug trials. This article describes an approach to establishing an academically led early phase trial portfolio, highlighting lessons learned and sharing experiences...
May 1, 2017: Clinical Trials: Journal of the Society for Clinical Trials
https://www.readbyqxmd.com/read/28531827/safety-and-performance-of-the-second-generation-enlightn%C3%A2-renal-denervation-system-in-patients-with-drug-resistant-uncontrolled-hypertension
#9
Stephen G Worthley, Gerard T Wilkins, Mark W Webster, Joseph K Montarello, Sinny Delacroix, Robert J Whitbourn, Roderic J Warren
BACKGROUND AND AIMS: Catheter-based renal denervation for the treatment of drug-resistant hypertension has been intensively investigated in recent years. To date, only limited data have been published using multi-electrode radiofrequency ablation systems that can deliver lesions with a pre-determined pattern. This study was designed to evaluate the safety and performance of the second generation EnligHTN™ Renal Denervation System. METHODS: This first-in-human, prospective, multi-center, non-randomized study included 39 patients (62% male, mean age 63 years, and mean baseline office blood pressure 174/93 mmHg) with drug-resistant hypertension...
May 3, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28531816/predicted-phototoxicities-of-carbon-nano-material-by-quantum-mechanical-calculations
#10
Don Betowski
The purpose of this research was to develop a predictive model for the phototoxicity potential of carbon nanomaterials (fullerenols and single-walled carbon nanotubes). This model is based on the quantum mechanical (ab initio) calculations on these carbon-based materials and comparison of the triplet excited states of these materials to published work relating phototoxicity of polynuclear aromatic hydrocarbons (PAH) to their predictive triplet excited state energy. A successful outcome will add another tool to the arsenal of predictive methods for the U...
March 31, 2017: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/28531301/a-political-case-of-penetrating-cranial-trauma-the-injury-of-james-scott-brady
#11
Richard Menger, Piyush Kalakoti, Rimal Hanif, Osama Ahmed, Anil Nanda, Bharat Guthikonda
James Brady, the White House press secretary during President Ronald Reagan's first term in office, was 1 of 4 people (including the President) wounded during an attempted assassination attempt on President Reagan's life on March 30, 1981. John Hinckley, Jr. was found not guilty of this attempt by reason of insanity. The assassination attempt was a ploy by Hinckley, Jr. to impress the actress Jodie Foster. Brady was the most seriously injured of the 4 who were wounded. He suffered a gunshot wound to the left forehead that traveled through the left frontal lobe, corpus callosum, and then into the right frontal and temporal lobes...
May 22, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28531258/the-reproducibility-of-racial-differences-in-ambulatory-blood-pressure-phenotypes-and-measurements
#12
Aamir Husain, Feng-Chang Lin, Laura A Tuttle, Emily Olsson, Anthony J Viera
BACKGROUND: We examined the reproducibility of differences in ambulatory blood pressure (BP) monitoring (ABPM) phenotypes and other parameters (sustained hypertension, masked hypertension, nocturnal hypertension, and nondipping) between African Americans and Whites. METHODS: A total of 420 participants untreated for hypertension attended 2 research visits 1 week apart during which traditional office BP averages and ABPM session averages were determined. We computed percent agreement in ABPM phenotypes across the 2 visits stratified by race and associated kappa statistics with 95% confidence intervals...
May 22, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28530851/chondral-injuries-and-irreparable-meniscal-tears-among-adolescents-with-anterior-cruciate-ligament-or-meniscal-tears-are-more-common-in-patients-with-public-insurance
#13
Ariel A Williams, Nickolas S Mancini, Matthew J Solomito, Carl W Nissen, Matthew D Milewski
BACKGROUND: Access to health care services is a critical component of health care reform and may differ among patients with different types of insurance. Hypothesis/Purpose: The purpose was to compare adolescents with private and public insurance undergoing surgery for anterior cruciate ligament (ACL) and/or meniscal tears. We hypothesized that patients with public insurance would have a delayed presentation from the time of injury and therefore would have a higher incidence of chondral injuries and irreparable meniscal tears and lower preoperative International Knee Documentation Committee (IKDC) scores than patients with private insurance...
May 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28530521/the-direct-cost-of-managing-a-rare-disease-assessing-medical-and-pharmacy-costs-associated-with-duchenne-muscular-dystrophy-in-the-united-states
#14
Sarah Thayer, Christopher Bell, Craig M McDonald
BACKGROUND: A Duchenne muscular dystrophy (DMD) cohort was identified using a claims-based algorithm to estimate health care utilization and costs for commercially insured DMD patients in the United States. Previous analyses have used broad diagnosis codes that include a range of muscular dystrophy types as a proxy to estimate the burden of DMD. OBJECTIVE: To estimate DMD-associated resource utilization and costs in a sample of patients identified via a claims-based algorithm using diagnosis codes, pharmacy prescriptions, and procedure codes unique to DMD management based on DMD clinical milestones...
June 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28530441/a-pilot-observational-study-of-an-acupressure-acupuncture-intervention-in-children-with-autism-spectrum-disorder
#15
Lana R Warren, Patricia A Rao, David C Paton
OBJECTIVES: To determine whether children with autism spectrum disorder (ASD) would tolerate an acupressure/acupuncture intervention and whether parents would adhere to a twice-weekly, 8-week intervention protocol. Second, to further understand best measures to use to capture impact of intervention on behavioral and regulatory functions. DESIGN: This is an observational pilot study with pre-, mid-, and postintervention measures. SETTINGS/LOCATION: The intervention was carried out in a private practice office in a large metropolitan area...
May 22, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28530069/-in-office-vocal-cord-injection-for-treatment-of-dysphonia
#16
Limor Benyamini, Faten Awwad, Ziv Gil, Jacob T Cohen
INTRODUCTION: Dysphonia significantly damages quality of life and employment opportunities. One of the common causes of hoarseness is glottic insufficiency, namely the lack of full adherence of the vocal cords during speech and swallowing. Correction is achieved by vocal cord medialization. OBJECTIVES: To examine the effect of vocal cord injection with carboxymethyl cellulose and hydroxyapatite under local anesthesia in the office, on the voice objectively, assessment by staff and patient satisfaction...
November 2016: Harefuah
https://www.readbyqxmd.com/read/28529299/a-study-on-the-jejungwon-hospital-building-in-jaedong-and-gurigae-and-uses-of-the-hospital-after-its-relocation
#17
Yeonkyung Lee
Jejungwon hospital, the first modern healthcare facility to be built in Korea, was built at Jaedong in 1885 and moved to Gurigae in 1887. Finally, it was moved to Dodong, outside the Namdaemun Gate, and its name was changed to Severance Hospital. The Jaedong Jejungwon hospital was located at a former house of HONG Youngsik, and it was expanded by renovating existing buildings and constructing new buildings in 2 years. The Gurigae Jejungwon hospital, which was located near Myeongdong Cathedral, was bigger than the Jaedong Jejungwon one and even provided residence to doctors...
December 2016: Ŭi Sahak
https://www.readbyqxmd.com/read/28528354/comparison-of-the-effectiveness-of-resistance-training-in-women-with-chronic-computer-related-neck-pain-a-randomized-controlled-study
#18
Xiao Li, Caina Lin, Cuicui Liu, Songjian Ke, Qing Wan, Haijie Luo, Zhuxi Huang, Wenjun Xin, Chao Ma, Shaoling Wu
BACKGROUND: Chronic computer-related neck pain is common among office workers. Studies have proposed neck strengthening exercise as a therapy to pain relieving and function improvement. The aim of this study was to compare the efficacy of different loading resistance trainings and we hypothesized that women with work-related neck pain could benefit more from progressive resistance training for pain and function recovery. METHODS: A randomized controlled trial was conducted and subjects characterized by monotonous jobs were recruited...
May 20, 2017: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/28528275/it-is-not-all-bad-for-the-grey-city-a-crossover-study-on-physiological-and-psychological-restoration-in-a-forest-and-an-urban-environment
#19
Ulrika K Stigsdotter, Sus Sola Corazon, Ulrik Sidenius, Jesper Kristiansen, Patrik Grahn
Today, urbanization presents a challenge to urban planning with regard to creating healthy living environments. The aim of this research is to gain further knowledge of the restorativeness of a best case urban and natural environment: that is a historic down town urban environment and forest environment located in an arboretum. The study has a cross-over design where 51 (N) female university students are exposed to the two environments through both seated viewing and walking. A mixed method approach is used with both physiological measurements of blood pressure (BP) and heart rate variability (HRV) and psychological measurements of mood change and perceived restorativeness...
May 18, 2017: Health & Place
https://www.readbyqxmd.com/read/28528245/can-inequality-be-tamed-through-boundary-work-a-qualitative-study-of-health-promotion-aimed-at-reducing-health-inequalities
#20
Pia Vivian Pedersen, Ulf Hjelmar, Mette Terp Høybye, Morten Hulvej Rod
This paper examines the organisational dynamics that arise in health promotion aimed at reducing health inequalities. The paper draws on ethnographic fieldwork among public health officers in Danish municipalities and qualitative interviews from an evaluation of health promotion programmes targeting homeless and other marginalised citizens. Analytically, we focus on 'boundary work', i.e. the ways in which social and symbolic boundaries are established, maintained, transgressed and negotiated, both at the administrative level and among frontline professionals...
May 10, 2017: Social Science & Medicine
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