keyword
MENU ▼
Read by QxMD icon Read
search

Laboral

keyword
https://www.readbyqxmd.com/read/29341027/developing-deep-learning-applications-for-life-science-and-pharma-industry
#1
Daniel Siegismund, Vasily Tolkachev, Stephan Heyse, Beate Sick, Oliver Duerr, Stephan Steigele
Deep Learning has boosted artificial intelligence over the past 5 years and is seen now as one of the major technological innovation areas, predicted to replace lots of repetitive, but complex tasks of human labor within the next decade. It is also expected to be 'game changing' for research activities in pharma and life sciences, where large sets of similar yet complex data samples are systematically analyzed. Deep learning is currently conquering formerly expert domains especially in areas requiring perception, previously not amenable to standard machine learning...
January 16, 2018: Drug Research
https://www.readbyqxmd.com/read/29340509/uncovering-a-tragic-flaw-in-revolutionary-health-policies-from-health-and-communicative-inequities-to-communicative-justice-in-health
#2
Charles L Briggs
This article analyzes a contradiction facing efforts by left-leaning governments in Latin America to transform health into a fundamental social right. Policies and practices that confront health inequities generally fail to address health/communicative inequities, hierarchical distributions of rights to shape what counts as legitimate knowledge of health. This ethnographic analysis focuses on an epidemic of a mysterious disease - identified clinically as bat-transmitted rabies - in the Delta Amacuro rainforest of Venezuela in 2007-2008, tracing how parents who lost 1-3 children faced acute health/communicative inequities in clinical settings, epidemiological investigations, work with healers, news coverage, health policy, and health communication...
July 2017: Salud Colectiva
https://www.readbyqxmd.com/read/29340386/on-chip-functional-neuroimaging-with-mechanical-stimulation-in-caenorhabditis-elegans-larvae-for-studying-development-and-neural-circuits
#3
Yongmin Cho, David N Oakland, Sol Ah Lee, William R Schafer, Hang Lu
Mechanosensation is fundamentally important for the abilities of an organism to experience touch, hear sounds, and maintain balance. Caenorhabditis elegans is a powerful system for studying mechanosensation as this worm is well suited for in vivo functional imaging of neurons. Many years of research using labor-intensive methods have generated a wealth of knowledge about mechanosensation in C. elegans, and the recent microfluidic-based platforms continue to push the boundary for this field. However, developmental aspects of sensory biology, including mechanosensation, are still not fully understood...
January 17, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/29339745/genomic-and-transcriptomic-analysis-of-the-asian-honeybee-apis-cerana-provides-novel-insights-into-honeybee-biology
#4
Qingyun Diao, Liangxian Sun, Huajun Zheng, Zhijiang Zeng, Shengyue Wang, Shufa Xu, Huoqing Zheng, Yanping Chen, Yuanyuan Shi, Yuezhu Wang, Fei Meng, Qingliang Sang, Lianfei Cao, Fang Liu, Yongqiang Zhu, Wenfeng Li, Zhiguo Li, Congjie Dai, Minjun Yang, Shenglu Chen, Runsheng Chen, Shaowu Zhang, Jay D Evans, Qiang Huang, Jie Liu, Fuliang Hu, Songkun Su, Jie Wu
The Asian honeybee Apis cerana is one of two bee species that have been commercially kept with immense economic value. Here we present the analysis of genomic sequence and transcriptomic exploration for A. cerana as well as the comparative genomic analysis of the Asian honeybee and the European honeybee A. mellifera. The genome and RNA-seq data yield new insights into the behavioral and physiological resistance to the parasitic mite Varroa the evolution of antimicrobial peptides, and the genetic basis for labor division in A...
January 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29339041/factors-influencing-women-s-perceptions-of-shared-decision-making-during-labor-and-delivery-results-from-a-large-scale-cohort-study-of-first-childbirth
#5
Laura B Attanasio, Katy B Kozhimannil, Kristen H Kjerulff
OBJECTIVE: To examine correlates of shared decision making during labor and delivery. METHODS: Data were from a cohort of women who gave birth to their first baby in Pennsylvania, 2009-2011 (N = 3006). We used logistic regression models to examine the association between labor induction and mode of delivery in relation to women's perceptions of shared decision making, and to investigate race/ethnicity and SES as potential moderators. RESULTS: Women who were Black and who did not have a college degree or private insurance were less likely to report high shared decision making, as well as women who underwent labor induction, instrumental vaginal or cesarean delivery...
January 5, 2018: Patient Education and Counseling
https://www.readbyqxmd.com/read/29338709/wormachine-machine-learning-based-phenotypic-analysis-tool-for-worms
#6
Adam Hakim, Yael Mor, Itai Antoine Toker, Amir Levine, Moran Neuhof, Yishai Markovitz, Oded Rechavi
BACKGROUND: Caenorhabditis elegans nematodes are powerful model organisms, yet quantification of visible phenotypes is still often labor-intensive, biased, and error-prone. We developed WorMachine, a three-step MATLAB-based image analysis software that allows (1) automated identification of C. elegans worms, (2) extraction of morphological features and quantification of fluorescent signals, and (3) machine learning techniques for high-level analysis. RESULTS: We examined the power of WorMachine using five separate representative assays: supervised classification of binary-sex phenotype, scoring continuous-sexual phenotypes, quantifying the effects of two different RNA interference treatments, and measuring intracellular protein aggregation...
January 16, 2018: BMC Biology
https://www.readbyqxmd.com/read/29338683/genomic-repeats-misassembly-and-reannotation-a-case-study-with-long-read-resequencing-of-porphyromonas-gingivalis-reference-strains
#7
Luis Acuña-Amador, Aline Primot, Edouard Cadieu, Alain Roulet, Frédérique Barloy-Hubler
BACKGROUND: Without knowledge of their genomic sequences, it is impossible to make functional models of the bacteria that make up human and animal microbiota. Unfortunately, the vast majority of publicly available genomes are only working drafts, an incompleteness that causes numerous problems and constitutes a major obstacle to genotypic and phenotypic interpretation. In this work, we began with an example from the class Bacteroidia in the phylum Bacteroidetes, which is preponderant among human orodigestive microbiota...
January 16, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29337695/automated-fabrication-of-photopatterned-gelatin-hydrogels-for-organ-on-chips-applications
#8
Janna C Nawroth, Lisa L Scudder, Ryan T Halvorson, Jason Tresback, John P Ferrier, Sean P Sheehy, Alex Cho, Suraj Kannan, Ilona Sunyovszki, Josue A Goss, Patrick H Campbell, Kevin Kit Parker
Organ-on-chip platforms aim to improve preclinical models for organ-level responses to novel drug compounds. Heart-on-a-chip assays in particular require tissue engineering techniques that rely on labor-intensive photolithographic fabrication or resolution-limited 3D printing of micropatterned substrates, which limits turnover and flexibility of prototyping. We present a rapid and automated method for large scale on-demand micropatterning of gelatin hydrogels for organ-on-chip applications using a novel biocompatible laser-etching approach...
January 16, 2018: Biofabrication
https://www.readbyqxmd.com/read/29337679/the-effects-of-physical-activity-on-chronic-subclinical-systemic-inflammation
#9
Alba Maria Dalbello Tir, Marina Labor, Davor Plavec
Chronic subclinical systemic inflammation (CSSI) is a pathogenic event and a common risk factor for many noncommunicable diseases like atherosclerosis, metabolic syndrome, cardiovascular disease, insulin resistance and type 2 diabetes, cancer, and obstructive lung disease. On the other hand, regular physical activity has been found to reduce this risk. Many studies of different design were conducted to assess the association between inflammatory mediators as markers of CSSI and regular physical activity. The aim of this review was to present the current level of evidence and understanding of potential mechanisms by which physical activity reduces inflammatory mediators involved in CSSI and the types of physical activity required for the expected effect...
December 20, 2017: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/29336638/prehospital-administration-of-epinephrine-in-pediatric-anaphylaxis-a-statewide-perspective
#10
Leslie M Cristiano, Brian Hiestand, Jason W Caldwell, W Adam Gower, Antonio R Fernandez, Katherine Gilbert, James E Winslow
OBJECTIVE: Timely administration of epinephrine is critical in the treatment of anaphylaxis. This study sought to determine the frequency of administration of epinephrine by EMS providers caring for pediatric patients in the prehospital setting. METHODS: We examined data from the NC EMS database (PreMIS) from 2010-3 to determine frequency of epinephrine administration in pediatric patients with anaphylaxis. We studied patients <18 years of age with an EMS provider impression of "allergic reaction...
January 16, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29336331/-job-status-after-the-resident-training-period-in-spain-analysis-of-a-national-survey
#11
Miguel García Sanz, Moises Rodríguez Socarrás, Leonardo Tortolero Blanco, Laura Pesquera-Ortega, Juan Colombo, Juan Gómez Rivas
OBJECTIVES: Since the establishment of specialization of medicine through the residency system, Spanish health care has sought to maintain a balance between established needs and trained professionals, with the aim of avoiding the deficit or excess of health specialists with its consequences. The objective of the present review is to know the working conditions of urologist specialists at the end of the residency training period. METHODS: The results of a survey for urologist who completed their residency contract from 2012 to 2016 are presented, assessing working status, academic and working data during the first months after the completion of specialized training...
January 2018: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/29336232/wealth-social-protection-programs-and-child-labor-in-colombia-a-cross-sectional-study
#12
Ángela María Pinzón-Rondón, Liseth B Cifuentes, Catalina Zuluaga, Juan Carlos Botero, Mariana Pinzon-Caicedo
This article has 3 main objectives: (1) to assess the prevalence of child labor in Colombia, (2) to identify factors associated with child labor, and (3) to determine whether social protection programs have an association with the prevalence of child labor in the country. Using a cross-sectional study with data from the Colombian Demographic and Health Survey 2010, a working child was defined as a child who worked during the week prior to the survey in an activity other than household chores. Through descriptive statistics, bivariate analysis, and multivariate regressions, it was found that child labor was associated with gender (boys were more likely to work), older age, ethnicity (children from indigenous communities were more likely to be workers), school dropout, disability (children with disabilities were less likely to be working), subsidized health social security system membership, and lower number of years of mother's schooling...
January 1, 2018: International Journal of Health Services: Planning, Administration, Evaluation
https://www.readbyqxmd.com/read/29334427/management-of-labor-are-the-new-guidelines-justified
#13
Wayne R Cohen, Melanie Sumersille, Emanuel A Friedman
No abstract text is available yet for this article.
January 15, 2018: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/29334390/smartphone-integrated-optoelectrowetting-sioew-for-on-chip-sample-processing-and-microscopic-detection-of-water-quality
#14
Dongyue Jiang, Seunguk Lee, Sung Woo Bae, Sung-Yong Park
With the increasing capabilities and ubiquity of smartphones and their associated digital cameras, this study presents a smartphone integrated optoelectrowetting (SiOEW) device as a simple, portable tool capable of on-chip water sample preparation and microscopic detection of the target cells in water samples, which significantly reduce the detection time and the labor cost required for water quality monitoring. A commercially available smartphone is used as a low-intensity portable light source to perform optoelectrowetting (OEW)-based microfluidic operations such as droplet transportation, merging, mixing, and immobilization on a hydrophobic detection zone...
January 15, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/29334294/comments-on-manuscript-early-amniotomy-after-dinoprostone-insert-used-for-the-induction-of-labor
#15
Ahmed M Abbas
No abstract text is available yet for this article.
January 15, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29332799/rapid-identification-of-regulated-organic-chemical-compounds-in-toys-using-ambient-ionization-and-a-miniature-mass-spectrometry-system
#16
Xiangyu Guo, Hua Bai, Yueguang Lv, Guangcheng Xi, Junfang Li, Xiaoxiao Ma, Yue Ren, Zheng Ouyang, Qiang Ma
Rapid, on-site analysis was achieved through significantly simplified operation procedures for a wide variety of toy samples (crayon, temporary tattoo sticker, finger paint, modeling clay, and bubble solution) using a miniature mass spectrometry system with ambient ionization capability. The labor-intensive analytical protocols involving sample workup and chemical separation, traditionally required for MS-based analysis, were replaced by direct sampling analysis using ambient ionization methods. A Mini β ion trap miniature mass spectrometer was coupled with versatile ambient ionization methods, e...
April 1, 2018: Talanta
https://www.readbyqxmd.com/read/29331208/wrist-a-wrist-image-segmentation-toolkit-for-carpal-bone-delineation-from-mri
#17
Brent Foster, Anand A Joshi, Marissa Borgese, Yasser Abdelhafez, Robert D Boutin, Abhijit J Chaudhari
Segmentation of the carpal bones from 3D imaging modalities, such as magnetic resonance imaging (MRI), is commonly performed for in vivo analysis of wrist morphology, kinematics, and biomechanics. This crucial task is typically carried out manually and is labor intensive, time consuming, subject to high inter- and intra-observer variability, and may result in topologically incorrect surfaces. We present a method, WRist Image Segmentation Toolkit (WRIST), for 3D semi-automated, rapid segmentation of the carpal bones of the wrist from MRI...
December 28, 2017: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/29330113/runt-related-transcription-factor-1-runx1-deficiency-attenuates-inflammation-induced-pro-inflammatory-and-pro-labour-mediators-in-myometrium
#18
Martha Lappas
Identifying new targets that regulate myometrial activation are required to develop effective treatments to stop preterm labor. Inflammation, which can be induced by sterile or infective insults, plays a role in initiating and maintaining uterine contractions. Several high throughput transcription screening studies have identified an upregulation of runt-related transcription factor 1 (RUNX1) mRNA expression in myometrium with labor. The role of RUNX1 in labor, however, is not known. We report increased RUNX1 during late gestation which was further augmented in labor, suggesting that RUNX1 may be involved in the transition of the myometrium from a quiescent into a contractile state in preparation for labor...
January 9, 2018: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/29329366/delineating-differential-regulatory-signatures-of-the-human-transcriptome-in-the-choriodecidua-and-myometrium-at-term-labor
#19
Sylvia Lui, Cyntia Duval, Farkhondeh Farrokhnia, Sylvie Girard, Lynda K Harris, Clare L Tower, Adam Stevens, Rebecca L Jones
Background: Preterm deliveries remain the leading cause of neonatal morbidity and mortality. Current therapies target only myometrial contractions and are largely ineffective. As labor involves multiple coordinated events across maternal and fetal tissues, identifying fundamental regulatory pathways of normal term labor is vital to understanding successful parturition and consequently labor pathologies. We aimed to identify transcriptomic signatures of human normal term labor of two tissues: in the fetal-facing choriodecidua and the maternal myometrium...
January 10, 2018: Biology of Reproduction
https://www.readbyqxmd.com/read/29329176/a-cost-analysis-of-gyrase-a-testing-and-targeted-ciprofloxacin-therapy-versus-recommended-2-drug-therapy-for-neisseria-gonorrhoeae-infection
#20
Lao-Tzu Allan-Blitz, Peera Hemarajata, Romney M Humphries, Adriane Wynn, Eddy R Segura, Jeffrey D Klausner
BACKGROUND: Novel approaches to combating drug-resistant Neisseria gonorrhoeae infections are urgently needed. Targeted therapy with ciprofloxacin has been made possible by a rapid assay for genotyping the gyrase A (gyrA) gene; a nonmutated gene reliably predicts susceptibility to ciprofloxacin. METHODS: We determined the costs of running the gyrA assay, 500 mg of ciprofloxacin, 250 mg of ceftriaxone injection, and 1000 mg of azithromycin. Cost estimates for gyrA testing included assay reagents and labor...
February 2018: Sexually Transmitted Diseases
keyword
keyword
101601
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"