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https://www.readbyqxmd.com/read/28225341/patterns-of-drug-resistance-among-patients-with-tuberculous-pleural-effusion-in-greece
#1
V Anastasakos, V Skouras, C Moschos, S Tsikrika, S Karabela, I Marinou, E Vogiatzakis, K Konstantinou, A Papavasiliou, I Kalomenidis
SETTING: Data on the relationship between pleural tuberculosis (TB) and anti-tuberculosis drug resistance are scarce. OBJECTIVE: To determine the patterns of drug resistance among pleural Mycobacterium tuberculosis isolates in Greece and the incidence of tuberculous pleural effusion (TPE) among patients with multidrug-resistant (MDR) or extensively drug-resistant (XDR) pulmonary TB. DESIGN: Drug susceptibility testing (DST) results recorded in the database of the National Reference Centre for Tuberculosis in Athens, Greece, over a 9-year period (2003-2011) were reviewed...
March 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28221128/epidemiology-of-nontuberculous-mycobacterial-lung-disease-and-tuberculosis-hawaii-usa
#2
Jennifer Adjemian, Timothy B Frankland, Yihe G Daida, Jennifer R Honda, Kenneth N Olivier, Adrian Zelazny, Stacey Honda, D Rebecca Prevots
Previous studies found Hawaiians and Asian-Americans/Pacific Islanders to be independently at increased risk for nontuberculous mycobacterial pulmonary disease (NTMPD) and tuberculosis (TB). To better understand NTM infection and TB risk patterns in Hawaii, USA, we evaluated data on a cohort of patients in Hawaii for 2005-2013. Period prevalence of NTMPD was highest among Japanese, Chinese, and Vietnamese patients (>300/100,000 persons) and lowest among Native Hawaiians and Other Pacific Islanders (50/100,000)...
March 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28218770/the-prevalence-and-radiological-findings-of-pulmonary-embolism-in-hiv-positive-patients-referred-for-computed-tomography-pulmonary-angiography-in-the-western-cape-of-south-africa
#3
Raksha Ramlakhan, Savvas Andronikou, Ashmitha Rajkumar
AIM: To provide imaging data and report associations between human immunodeficiency virus (HIV), tuberculosis (TB) and pulmonary embolism (PE) in a South African population that underwent computed tomography pulmonary angiography (CTPA) for suspected PE. METHODS: A validated Qanadli severity scoring system for PE was used for 164 CTPA scans, and parenchymal, pleural and cardiovascular complications were reported. Serological confirmation of HIV testing and microbiological confirmation of TB were recorded...
February 15, 2017: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/28216065/preliminary-evaluation-of-a-telephone-based-smoking-cessation-intervention-in-the-lung-cancer-screening-setting-a-randomized-clinical-trial
#4
Kathryn L Taylor, Charlotte J Hagerman, George Luta, Paula G Bellini, Cassandra Stanton, David B Abrams, Jenna A Kramer, Eric Anderson, Shawn Regis, Andrea McKee, Brady McKee, Ray Niaura, Harry Harper, Michael Ramsaier
: Incorporating effective smoking cessation interventions into lung cancer screening (LCS) programs will be essential to realizing the full benefit of screening. We conducted a pilot randomized trial to determine the feasibility and efficacy of a telephone-counseling (TC) smoking cessation intervention vs. usual care (UC) in the LCS setting. In collaboration with 3 geographically diverse LCS programs, we enrolled current smokers (61.5% participation rate) who were: registered to undergo LCS, 50-77 years old, and had a 20+ pack-year smoking history...
February 14, 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28207570/international-survey-of-critically-ill-children-with-acute-neurologic-insults-the-prevalence-of-acute-critical-neurological-disease-in-children-a-global-epidemiological-assessment-study
#5
Ericka L Fink, Patrick M Kochanek, Robert C Tasker, John Beca, Michael J Bell, Robert S B Clark, Jamie Hutchison, Monica S Vavilala, Anthony Fabio, Derek C Angus, R Scott Watson
OBJECTIVE: The international scope of critical neurologic insults in children is unknown. Our objective was to assess the prevalence and outcomes of children admitted to PICUs with acute neurologic insults. DESIGN: Prospective study. SETTING: Multicenter (n = 107 PICUs) and multinational (23 countries, 79% in North America and Europe). PATIENTS: Children 7 days to 17 years old admitted to the ICU with new traumatic brain injury, stroke, cardiac arrest, CNS infection or inflammation, status epilepticus, spinal cord injury, hydrocephalus, or brain mass...
February 15, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28198990/corticosteroids-and-hip-fracture-risk-in-elderly-respiratory-patients-epic-greece-cohort
#6
Anna Karakatsani, Michail Katsoulis, Eleni Klinaki, Antonia Trichopoulou
INTRODUCTION: In an ageing population the prevalence of osteoporosis and chronic respiratory diseases is expected to increase in the near future. Interestingly, several forms of corticosteroids, drugs implicated in osteoporosis pathogenesis, are prescribed to respiratory patients without taking into consideration their age and risk for osteoporotic fractures. The aim of this study was to investigate the risk for hip fracture of the elder individuals who are taking corticosteroids for respiratory disease, including inhalers...
2017: Adv Respir Med
https://www.readbyqxmd.com/read/28198635/impact-of-comorbidities-by-age-on-symptom-presentation-for-suspected-acute-coronary-syndromes-in-the-emergency-department
#7
Larisa A Burke, Anne G Rosenfeld, Mohamud R Daya, Karen M Vuckovic, Jessica K Zegre-Hemsey, Maria Felix Diaz, Josemare Tosta Daiube Santos, Sahereh Mirzaei, Holli A DeVon
BACKGROUND: It is estimated half of acute coronary syndrome (ACS) patients have one or more associated comorbid conditions. AIMS: Aims were to: 1) examine the prevalence of comorbid conditions in patients presenting to the emergency department with symptoms suggestive of ACS; 2) determine if comorbid conditions influence ACS symptoms; and 3) determine if comorbid conditions predict the likelihood of receiving an ACS diagnosis. METHODS: A total of 1064 patients admitted to five emergency departments were enrolled in this prospective study...
February 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28197023/genitourinary-sarcoidosis-an-essential-review-for-the-practicing-clinician
#8
REVIEW
Norman L Block, Bruce R Kava
INTRODUCTION: Sarcoidosis is a multisystem disease that commonly involves the lungs, but may also present with extrapulmonary manifestations. Genitourinary (GU) tract involvement has been traditionally thought to be rare, but that view may underestimate the true prevalence of the disease due to the often, silent presentation thereof. METHODS: The literature pertaining to sarcoidosis from the general systemic point of view, etiology and therapy and with regard to specific organs was reviewed by identifying key words in a PubMed search...
January 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28194083/asbestos-induced-lung-disease-in-small-scale-clutch-manufacturing-workers
#9
Dipti Gothi, Tanushree Gahlot, Ram B Sah, Mayank Saxena, U C Ojha, Anand K Verma, Sonam Spalgais
BACKGROUND: The crocidolite variety of asbestos is banned. However, chrysotile, which is not prohibited, is still used in developing countries in making products such as clutch plate. Fourteen workers from a small-scale clutch plate-manufacturing factory were analyzed for asbestos-induced lung disease as one of their colleagues had expired due to asbestosis. AIMS: This study was conducted to evaluate the awareness of workers, the prevalence and type of asbestos-induced lung disease, and the sensitivity and specificity of diffusion test...
May 2016: Indian Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28193558/allergic-disease-associations-with-regional-and-localized-estimates-of-air-pollution
#10
Amy A Schultz, Jamie J Schauer, Kristen Mc Malecki
BACKGROUND: Exposure to multiple types of air pollution may contribute to and exacerbate allergic diseases including asthma and wheezing. However, few studies have examined chronic air pollution exposure and allergic disease outcomes among an adult population. Associations between potential estimates of annual average fine particulate matter (PM2.5), traffic related air pollution, and industrial source air emissions and three allergic disease outcomes (asthma, allergies and wheezing) were examined in a state-wide general population of adults...
February 10, 2017: Environmental Research
https://www.readbyqxmd.com/read/28191295/small-cell-carcinoma-of-the-prostate-in-an-elderly-patient-a-case-report-and-review-of-the-literature
#11
Dale Alan Whitaker, Daniel H Miller, Niveditha Jagadesh, Gerald W Strong, Lauren Hintenlang, William B Schenk, Gregory A Broderick, Katherine S Tzou, Steven J Buskirk
Prostate cancer is the most common malignancy of men in the United States. Small-cell carcinoma (SCC), which typically presents as an aggressive lung malignancy, is a rare diagnosis within the setting of prostate cancer pathology. Due to its limited prevalence, little information regarding the treatment and prognosis of this disease in large populations is available. To date our current knowledge base is largely limited to case reports and retrospective case reviews. The mainstay of treatment for this particular histology most often involves a multimodality approach utilizing chemotherapy in conjunction with radiation therapy, androgen deprivation therapy, or prostatectomy...
November 17, 2016: Rare Tumors
https://www.readbyqxmd.com/read/28185464/differences-in-age-distribution-oncological-diagnoses-and-stage-in-roma-and-non-roma-cancer-patients-registered-at-the-outpatient-oncology-department-poprad-in-2014-and-2015-a-retrospective-study
#12
M Reckova, J Mardiak, J Beniak, M Kakalejcik, L Medvecova, S Cingelová, M Mego
BACKGROUND: Roma (Gypsies) constitute the largest ethnic minority in Slovakia. Although some studies have reported a higher prevalence of communicable diseases in Roma, there have been no studies on cancer prevalence in Roma. The aim of this study was to compare differences in age at diagnosis, oncological diagnoses, and stage between Roma and non-Roma patients registered at a single oncology outpatient department in Eastern Slovakia where substantial numbers of Roma patients are treated...
2017: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/28182861/diffuse-pulmonary-ossification-in-fibrosing-interstitial-lung-diseases-prevalence-and-associations
#13
Ryoko Egashira, Joseph Jacob, Maria A Kokosi, Anne-Laure Brun, Alexandra Rice, Andrew G Nicholson, Athol U Wells, David M Hansell
Purpose To investigate the prevalence of diffuse pulmonary ossification (DPO) in patients with fibrosing interstitial lung disease (ILD) and determine whether there are differences among the types of ILDs. Materials and Methods Institutional review board approval was given and patient consent was not required for this study. The study population comprised 892 consecutive patients with fibrosing ILD, including 456 patients with idiopathic pulmonary fibrosis (IPF) (men, 366; women, 90; median age, 72 years [range, 38-93 years]), 244 with nonspecific interstitial pneumonia (men, 79; women, 165; median age, 60...
February 9, 2017: Radiology
https://www.readbyqxmd.com/read/28182031/allergies-in-urban-versus-countryside-settings-in-poland-as-part-of-the-epidemiology-of-the-allergic-diseases-in-poland-ecap-study-challenge-the-early-differential-diagnosis
#14
Edyta Krzych-Fałta, Konrad Furmańczyk, Barbara Piekarska, Aneta Tomaszewska, Adam Sybilski, Bolesław K Samoliński
INTRODUCTION: The incidence of allergies depends on a number of factors, including adopting an urban "western" lifestyle, genetic predispositions, and different regions of residence. AIM: To compare the prevalence of allergic conditions (seasonal allergic rhinitis (SAR) and perennial allergic rhinitis (PAR), bronchial asthma (BA), atopic dermatitis (AD)) in a group of countryside versus urban residents in Poland. MATERIAL AND METHODS: The prevalence of allergic conditions in urban versus countryside settings was assessed using the translated and approved questionnaire developed for international ECRHS II and ISAAC studies...
October 2016: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/28178325/prevalence-and-clinical-relevance-of-helminth-co-infections-among-tuberculosis-patients-in-urban-tanzania
#15
Francis Mhimbira, Jerry Hella, Khadija Said, Lujeko Kamwela, Mohamed Sasamalo, Thomas Maroa, Magreth Chiryamkubi, Grace Mhalu, Christian Schindler, Klaus Reither, Stefanie Knopp, Jürg Utzinger, Sébastien Gagneux, Lukas Fenner
BACKGROUND: Helminth infections can negatively affect the immunologic host control, which may increase the risk of progression from latent Mycobacterium tuberculosis infection to tuberculosis (TB) disease and alter the clinical presentation of TB. We assessed the prevalence and determined the clinical relevance of helminth co-infection among TB patients and household contact controls in urban Tanzania. METHODOLOGY: Between November 2013 and October 2015, we enrolled adult (≥18 years) sputum smear-positive TB patients and household contact controls without TB during an ongoing TB cohort study in Dar es Salaam, Tanzania...
February 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28177518/unique-prevalence-of-oncogenic-genetic-alterations-in-young-patients-with-lung-adenocarcinoma
#16
Kosuke Tanaka, Toyoaki Hida, Yuko Oya, Tatsuya Yoshida, Junichi Shimizu, Tetsuya Mizuno, Hiroaki Kuroda, Noriaki Sakakura, Kenichi Yoshimura, Yoshitsugu Horio, Yukinori Sakao, Yasushi Yatabe
BACKGROUND: Lung adenocarcinoma in the young is a rare entity, and the oncogenic genetic alterations (GAs) and clinical characteristics associated with this disease are poorly understood. Conversely, it has been demonstrated that young age at diagnosis defines unique biology in other cancers. For this report, the effects of young age on lung adenocarcinoma are reported. METHODS: The authors retrospectively screened 1746 consecutive patients who were diagnosed with stage I through IV adenocarcinoma between 2009 and 2015 and identified 81 who were aged 40 years or younger at diagnosis...
February 8, 2017: Cancer
https://www.readbyqxmd.com/read/28175924/morbidity-and-causes-of-death-in-patients-with-cutaneous-t-cell-lymphoma-in-finland
#17
Liisa Väkevä, Tuomas Lipsanen, Harri Sintonen, Annamari Ranki
Cutaneous T-cell lymphomas (CTCL), especially mycosis fungoides, can be considered as a state of longstanding low-grade systemic inflammation. Many studies have focused on secondary cancers with CTCL, but information about comorbidities is limited. A total of 144 patients with CTCL at Helsinki University Central Hospital during 2005 to 2015 were studied to determine associated comorbidities and causes of death in this cohort. Compared with an age-standardized control population, the prevalence of type 2 diabetes mellitus was increased among patients with CTCL with no link to obesity...
February 8, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28169347/attenuation-of-lymphocyte-immune-responses-during-mycobacterium-avium-complex-induced-lung-disease-due-to-increasing-expression-of-programmed-death-1-on-lymphocytes
#18
Chin-Chung Shu, Jann-Yuan Wang, Ming-Fang Wu, Chen-Tu Wu, Hsin-Chih Lai, Li-Na Lee, Bor-Luen Chiang, Chong-Jen Yu
Mycobacterium avium complex-induced lung disease (MAC-LD) becomes important due to its increasing prevalence. Attenuated cellular immunity associated with programmed cell death (PD)-1 may play a pathophysiological role in MAC-LD but lacks of investigation. We enrolled 80 participants in this prospective study, including 50 with MAC-LD and 30 healthy controls. Peripheral blood mononuclear cells (PBMCs), lymphocytes and monocyte-derived macrophages were used for MAC antigen stimulation. Patients with MAC-LD had lower tumor necrosis factor-α and interferon-γ responses compared to the healthy controls in PBMC stimulation assays with MAC bacilli...
February 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28168855/vaccination-of-calves-with-mycobacterium-bovis-bacillus-calmette-guerin-reduces-the-frequency-and-severity-of-lesions-of-bovine-tuberculosis-under-a-natural-transmission-setting-in-ethiopia
#19
G Ameni, K Tafess, A Zewde, T Eguale, M Tilahun, T Hailu, A Sirak, F J Salguero, S Berg, A Aseffa, R G Hewinson, H M Vordermeier
Bovine tuberculosis (bTB) is highly prevalent in intensive dairy farms of the urban "milk-sheds" in Ethiopia, and vaccination could be a cost-effective disease control strategy. In the present study, the efficacy of Bacillus Calmette-Guerin (BCG) to protect against bTB was assessed in Holstein-Friesian calves in a natural transmission setting. Twenty-three 2-week-old calves were subcutaneously vaccinated with BCG Danish SSI strain 1331, and matched 26 calves were injected with placebo. Six weeks later, calves were introduced into a herd of M...
February 6, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/28166832/prevalence-genetic-identity-and-vertical-transmission-of-babesia-microti-in-three-naturally-infected-species-of-vole-microtus-spp-cricetidae
#20
Katarzyna Tołkacz, Małgorzata Bednarska, Mohammed Alsarraf, Dorota Dwużnik, Maciej Grzybek, Renata Welc-Falęciak, Jerzy M Behnke, Anna Bajer
BACKGROUND: Vertical transmission is one of the transmission routes for Babesia microti, the causative agent of the zoonotic disease, babesiosis. Congenital Babesia invasions have been recorded in laboratory mice, dogs and humans. The aim of our study was to determine if vertical transmission of B. microti occurs in naturally-infected reservoir hosts of the genus Microtus. METHODS: We sampled 124 common voles, Microtus arvalis; 76 root voles, M. oeconomus and 17 field voles, M...
February 6, 2017: Parasites & Vectors
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