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https://www.readbyqxmd.com/read/29765187/gross-motor-skill-development-of-kindergarten-children-in-japan
#1
Thanda Aye, Tsugumi Kuramoto-Ahuja, Tamae Sato, Kaori Sadakiyo, Miyoko Watanabe, Hitoshi Maruyama
[Purpose] The purposes of this study were to assess and explore the gender-based differences in gross motor skill development of 5-year-old Japanese children. [Subjects and Methods] This cross-sectional study recruited 60 healthy 5-year-old (third-year kindergarten, i.e., nencho ) children (34 boys, 26 girls) from one local private kindergarten school in Otawara city, Tochigi Prefecture, Japan. Gross motor skills, including six locomotor and six object control skills, were assessed using the test of gross motor development, second edition (TGMD-2)...
May 2018: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/29755037/do-young-women-need-treatment-for-hypertension-after-pregnancy-complications
#2
EDITORIAL
Christina Y L Aye, Einas Elmahi, Henry Boardman, Paul Leeson
No abstract text is available yet for this article.
May 13, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29747667/protective-effect-of-grape-seed-and-skin-extract-against-high-fat-diet-induced-dyshomeostasis-of-energetic-metabolism-in-rat-lung
#3
Mohamed El Ayed, Safwen Kadri, Maha Mabrouk, Ezzedine Aouani, Salem Elkahoui
BACKGROUND: Obesity is currently one of the major epidemics of this millennium and affects poeples throughout the world. It causes multiple systemic complications as it significantly interferes with respiratory function. OBJECTIVE: We aimed in the present work to study the effect of high fat diet (HFD) on lung oxidative stress and energy metabolism alterations, as well as the putative protection afforded by grape seed and skin extract (GSSE). METHODS: We started by characterizing the GSSE and its composition using gas chromatography coupled to mass spectrometry (GC-MS)...
May 10, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29740461/genome-wide-association-mapping-of-seedling-and-adult-plant-resistance-to-barley-stripe-rust-puccinia-striiformis-f-sp-hordei-in-india
#4
Andrea Visioni, Sanjaya Gyawali, Rajan Selvakumar, Om P Gangwar, Pradeep S Shekhawat, Subhash C Bhardwaj, Ayed M Al-Abdallat, Zakaria Kehel, Ramesh P S Verma
Barley stripe rust is caused by Puccinia striiformis f.sp. hordei , (Psh), occurs worldwide, and is a major disease in South Asia. The aim of this work was to identify and estimate effects of loci underlying quantitative resistance to rust at seedling and adult plant stages. HI-AM panel of 261 barley genotypes consisting of released cultivars from North and South America, Europe, Australia, advanced breeding lines, and local landraces from ICARDA barley program were screened at seedling and adult plant stages for resistance to Psh...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29739677/soy-isoflavones-improve-cardiovascular-disease-risk-markers-in-women-during-the-early-menopause
#5
T Sathyapalan, M Aye, A S Rigby, N J Thatcher, S R Dargham, E S Kilpatrick, S L Atkin
BACKGROUND: Hormone replacement therapy may be beneficial for cardiovascular disease risk (CVR) in post-menopausal women. Soy isoflavones may act as selective estrogen receptor modulators. The aim of this study was to evaluate whether soy isoflavones had an effect on CVR markers. METHODS: The expected 10-year risk of cardiovascular disease and mortality were calculated as a secondary endpoint from a double blind randomised parallel study involving 200 women (mean age 55 years, Caucasian, Hull, UK, 2012) in the early menopause who were randomised to 15 g soy protein with 66 mg isoflavone (SPI) or 15 g soy protein alone (depleted of all isoflavones; SP) given as a snack bar between meals daily for 6 months...
April 10, 2018: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29720672/fty720-decreases-tumorigenesis-in-group-3-medulloblastoma-patient-derived-xenografts
#6
Evan F Garner, Adele P Williams, Laura L Stafman, Jamie M Aye, Elizabeth Mroczek-Musulman, Blake P Moore, Jerry E Stewart, Gregory K Friedman, Elizabeth A Beierle
Group 3 tumors account for 28% of medulloblastomas and have the worst prognosis. FTY720, an immunosuppressant currently approved for treatment of multiple sclerosis, has shown antitumor effects in several human cancer cell lines. We hypothesized that treatment with FTY720 (fingolimod) would decrease tumorigenicity in medulloblastoma patient-derived xenografts (PDXs). Three Group 3 medulloblastoma PDXs (D341, D384 and D425) were utilized. Expression of PP2A and its endogenous inhibitors I2PP2A and CIP2A was detected by immunohistochemistry and immunoblotting...
May 2, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29718706/myc-nick-promotes-efferocytosis-through-m2-macrophage-polarization-during-resolution-of-inflammation
#7
Xiancai Zhong, Ha-Na Lee, Seung Hyeon Kim, Sin-Aye Park, Wonki Kim, Young-Nam Cha, Young-Joon Surh
A key event required for effective resolution of inflammation is efferocytosis, which is defined as phagocytic removal of apoptotic cells mostly by macrophages acquiring an alternatively activated phenotype (M2). c-Myc has been reported to play a role in alternative activation of human macrophages and is proposed as one of the M2 macrophage markers. We found that M2-like peritoneal macrophages from zymosan A-treated mice exhibited a marked accumulation of Myc-nick, a truncated protein generated by a Calpain-mediated proteolytic cleavage of full-length c-Myc...
May 2, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29710838/assessment-of-genetic-diversity-among-pleurotus-spp-isolates-from-jordan
#8
Hanan Aref Hasan, Ahmad Mohamad Almomany, Shireen Hasan, Ayed M Al-Abdallat
Pleurotus is considered an important genus that belongs to the family Pleurotaceae and includes the edible King Oyster mushroom ( Pleurotus eryngii ). In the present study, 19 Pleurotus isolates were collected from two locations in the north of Jordan (Tell ar-Rumman and Um-Qais). The morphological characteristics among collected isolates revealed that there was a morphological similarity among the collected isolates. Nucleotide sequence analysis of the internal transcribed spacer (ITS1⁻5.8S rDNA⁻ITS4 region) and 28S nuclear large subunit (nLSU) in the ribosomal DNA gene of the isolated stains showed that all of them share over 98% sequence similarity with P...
April 29, 2018: Journal of Fungi (Basel, Switzerland)
https://www.readbyqxmd.com/read/29703004/a-rational-emotive-stress-management-intervention-for-reducing-job-burnout-and-dysfunctional-distress-among-special-education-teachers-an-effect-study
#9
Samuel C Ugwoke, Chiedu Eseadi, Liziana N Onuigbo, Eucharia N Aye, Immaculata N Akaneme, Angie I Oboegbulem, Ifeyinwa O Ezenwaji, Anthonia U Nwobi, Okechukwu O Nwaubani, Bernedeth N Ezegbe, Moses O Ede, Chibueze T Orji, Joseph C Onuoha, Eucharia U Onu, Francisca Okeke, Patricia Agu, Joachim C Omeje, Faith Omeke, Romanus Ugwu, Florence Arumede, Annastasia Eneh
BACKGROUND: Job-related burnout and distress are adverse stress responses which affect individuals in their occupational environment. This study aimed at investigating the effect of a rational-emotive stress management program on job burnout and dysfunctional distress among special education teachers in Nigeria. METHODS: A pretest-posttest randomized control group design was used. The participants in the study were 54 special education teachers. Data were collected using self-report questionnaires...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29692801/icn718-an-updated-and-improved-genome-scale-metabolic-network-reconstruction-of-acinetobacter-baumannii-aye
#10
Charles J Norsigian, Erol Kavvas, Yara Seif, Bernhard O Palsson, Jonathan M Monk
Acinetobacter baumannii has become an urgent clinical threat due to the recent emergence of multi-drug resistant strains. There is thus a significant need to discover new therapeutic targets in this organism. One means for doing so is through the use of high-quality genome-scale reconstructions. Well-curated and accurate genome-scale models (GEMs) of A. baumannii would be useful for improving treatment options. We present an updated and improved genome-scale reconstruction of A. baumannii AYE, named iCN718, that improves and standardizes previous A...
2018: Frontiers in Genetics
https://www.readbyqxmd.com/read/29691387/fetal-demise-and-failed-antibody-therapy-during-zika-virus-infection-of-pregnant-macaques
#11
Diogo M Magnani, Thomas F Rogers, Nicholas J Maness, Nathan D Grubaugh, Nathan Beutler, Varian K Bailey, Lucas Gonzalez-Nieto, Martin J Gutman, Núria Pedreño-Lopez, Jaclyn M Kwal, Michael J Ricciardi, Tereance A Myers, Justin G Julander, Rudolf P Bohm, Margaret H Gilbert, Faith Schiro, Pyone P Aye, Robert V Blair, Mauricio A Martins, Kathrine P Falkenstein, Amitinder Kaur, Christine L Curry, Esper G Kallas, Ronald C Desrosiers, Pascal J Goldschmidt-Clermont, Stephen S Whitehead, Kristian G Andersen, Myrna C Bonaldo, Andrew A Lackner, Antonito T Panganiban, Dennis R Burton, David I Watkins
Zika virus (ZIKV) infection of pregnant women is associated with pathologic complications of fetal development. Here, we infect pregnant rhesus macaques (Macaca mulatta) with a minimally passaged ZIKV isolate from Rio de Janeiro, where a high rate of fetal development complications was observed. The infection of pregnant macaques with this virus results in maternal viremia, virus crossing into the amniotic fluid (AF), and in utero fetal deaths. We also treated three additional ZIKV-infected pregnant macaques with a cocktail of ZIKV-neutralizing human monoclonal antibodies (nmAbs) at peak viremia...
April 24, 2018: Nature Communications
https://www.readbyqxmd.com/read/29686692/new-geographical-insights-of-the-latest-expansion-of-fusarium-oxysporum-f-sp-cubense-tropical-race-4-into-the-greater-mekong-subregion
#12
Si-Jun Zheng, Fernando A García-Bastidas, Xundong Li, Li Zeng, Tingting Bai, Shengtao Xu, Kesuo Yin, Hongxiang Li, Gang Fu, Yanchun Yu, Liu Yang, Huy Chung Nguyen, Bounneuang Douangboupha, Aye Aye Khaing, Andre Drenth, Michael F Seidl, Harold J G Meijer, Gert H J Kema
Banana is the most popular and most exported fruit and also a major food crop for millions of people around the world. Despite its importance and the presence of serious disease threats, research into this crop is limited. One of those is Panama disease or Fusarium wilt. In the previous century Fusarium wilt wiped out the "Gros Michel" based banana industry in Central America. The epidemic was eventually quenched by planting "Cavendish" bananas. However, 50 years ago the disease recurred, but now on "Cavendish" bananas...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29686526/-alert-audit-act-assessment-of-surveillance-and-response-strategy-for-malaria-elimination-in-three-low-endemic-settings-of-myanmar-in-2016
#13
Aye Mon Mon Kyaw, Soundappan Kathirvel, Mrinalini Das, Badri Thapa, Nay Yi Yi Linn, Thae Maung Maung, Zaw Lin, Aung Thi
Background: Myanmar, a malaria endemic country of Southeast Asia, adopted surveillance and response strategy similar to "1-3-7" Chinese strategy to achieve sub-national elimination in six low-endemic region/states of the country. Among these, Yangon, Bago-East, and Mon region/states have implemented this malaria surveillance and response strategy with modification in 2016. The current study was conducted to assess the case notification, investigation, classification, and response strategy (NICR) in these three states...
2018: Tropical Medicine and Health
https://www.readbyqxmd.com/read/29675980/longitudinal-assessment-of-hippocampus-structure-in-children-with-type-1-diabetes
#14
Lara C Foland-Ross, Allan L Reiss, Paul K Mazaika, Nelly Mauras, Stuart A Weinzimer, Tandy Aye, Michael J Tansey, Neil H White
The extant literature finds that children with type 1 diabetes (T1D) experience mild cognitive alterations compared to healthy age-matched controls. The neural basis of these cognitive differences is unclear but may relate in part to the effects of dysglycemia on the developing brain. We investigated longitudinal changes in hippocampus volume in young children with early-onset T1D. Structural magnetic resonance imaging data were acquired from 142 children with T1D and 65 age-matched control subjects (4-10 years of age at study entry) at two time points, 18 months apart...
April 19, 2018: Pediatric Diabetes
https://www.readbyqxmd.com/read/29667597/much-work-remains-to-be-done-in-the-intensive-care-of-patients-with-malignant-haemopathies
#15
S Yaacoubi, S Ayed, C Bornstain, F Vincent, For The Grrr-Oh Groupe de Recherche Respiratoire En Réanimation En Onco-Hématologie Http/Www Grrroh Com/
No abstract text is available yet for this article.
April 2018: Netherlands Journal of Medicine
https://www.readbyqxmd.com/read/29665003/the-inside-tract-the-appendicular-cecal-and-colonic-microbiome-of-captive-aye-ayes
#16
Lydia K Greene, Erin A McKenney
OBJECTIVES: The aye-aye (Daubentonia madagascariensis) is famous for its feeding strategies that target structurally defended, but high-quality resources. Nonetheless, the influence of this digestible diet on gut microbial contributions to aye-aye metabolism and nutrition remains unexplored. When four captive aye-ayes were unexpectedly lost to persin toxicity, we opportunistically collected samples along the animals' gastrointestinal tracts. Here we describe the diversity and composition of appendicular, cecal, and colonic consortia relative to the aye-aye's unusual feeding ecology...
April 17, 2018: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/29652864/honey-bee-as-alternative-medicine-to-treat-eleven-multidrug-resistant-bacteria-causing-urinary-tract-infection-during-pregnancy
#17
Mabrouka Bouacha, Hayette Ayed, Nedjoud Grara
Medicinal benefits of honey bee have been recognized in the medical community since ancient times as a remedy for many diseases and infections. This study aimed to investigate the in vitro susceptibility of 11 multidrug-resistant bacterial strains, isolated from urinary tract infections of pregnant women, to six honey samples collected from different localities in the east of Algeria. The evaluation of the antibacterial activity was performed by the well method followed by the broth dilution method using two-fold dilutions of each honey sample ranging from 2...
April 13, 2018: Scientia Pharmaceutica
https://www.readbyqxmd.com/read/29643332/macrophage-derived-il-1%C3%AE-nf-%C3%AE%C2%BAb-signaling-mediates-parenteral-nutrition-associated-cholestasis
#18
Karim C El Kasmi, Padade M Vue, Aimee L Anderson, Michael W Devereaux, Swati Ghosh, Natarajan Balasubramaniyan, Sophie A Fillon, Carola Dahrenmoeller, Ayed Allawzi, Crystal Woods, Sarah McKenna, Clyde J Wright, Linda Johnson, Angelo D'Alessandro, Julie A Reisz, Eva Nozik-Grayck, Frederick J Suchy, Ronald J Sokol
In infants intolerant of enteral feeding because of intestinal disease, parenteral nutrition may be associated with cholestasis, which can progress to end-stage liver disease. Here we show the function of hepatic macrophages and phytosterols in parenteral nutrition-associated cholestasis (PNAC) pathogenesis using a mouse model that recapitulates the human pathophysiology and combines intestinal injury with parenteral nutrition. We combine genetic, molecular, and pharmacological approaches to identify an essential function of hepatic macrophages and IL-1β in PNAC...
April 11, 2018: Nature Communications
https://www.readbyqxmd.com/read/29626659/modeling-based-optimization-approaches-for-the-development-of-anti-agrobacterium-tumefaciens-activity-using-streptomyces-sp-tn71
#19
Slim Smaoui, Karim Ennouri, Ahlem Chakchouk-Mtibaa, Imen Sellem, Kameleddine Bouchaala, Ines Karray-Rebai, Rayda Ben Ayed, Florence Mathieu, Lotfi Mellouli
A new aerobic bacterium TN71 was isolated from Tunisian Saharan soil and has been selected for its antimicrobial activity against phytopathogenic bacteria. Based on cellular morphology, physiological characterization and phylogenetic analysis, this isolate has been assigned as Streptomyces sp. TN71 strain. In an attempt to increase its anti-Agrobacterium tumefaciens activity, GYM + S (glucose, yeast extract, malt extract and starch) medium was selected out of five different production media and the medium composition was optimized...
April 4, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29626354/second-regional-plasmapheresis-conference-and-workshop-for-southeast-asia-sea-on-the-immunomodulatory-role-of-plasma-exchange-in-central-and-peripheral-nervous-system-disorders-kuala-lumpur-malaysia-9th-december-2017
#20
Shanthi Viswanathan, Stefanie Kar Yan Hung, Vinay Goyal, Metha Apiwattanakul, Umapathi N Thirugnanam, Suhailah Abdullah, Seinn Mya Mya Aye, Ohnmar Ohnmar, Le Tri Si, Saysavath Keosodsay, Riwanti Estiasari, Najib Khalife, Fu Liong Hiew
In December 2017, 79 delegates attended the 2nd regional plasmapheresis conference and workshop for Southeast Asia (SEA) on the immunomodulatory role of plasma exchange in central and peripheral nervous system disorders in Kuala Lumpur, Malaysia. This meeting featured 6 plenary lectures, interactive sessions dedicated for experience sharing, case presentations, and a practical session for paramedics. Clinical experts and researchers from 7 SEA countries and India shared experience and challenges in treating autoimmune neurological disorders...
April 6, 2018: Journal of Clinical Apheresis
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