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https://www.readbyqxmd.com/read/28803252/two-dimensional-echocardiography-estimates-of-fetal-ventricular-mass-throughout-gestation
#1
Christina Y L Aye, Adam James Lewandowski, Eric O Ohuma, Ross Upton, Alice Packham, Yvonne Kenworthy, Fenella Roseman, Tess Norris, Malid Molloholli, Sikolia Wanyonyi, Aris T Papageorghiou, Paul Leeson
BACKGROUND: Two-dimensional (2D) ultrasound quality has improved in recent years. Quantification of cardiac dimensions is important to screen and monitor certain fetal conditions. We assessed the feasibility and reproducibility of fetal ventricular measures using 2D echocardiography, reported normal ranges in our cohort, and compared estimates to other modalities. METHODS: Mass and end-diastolic volume were estimated by manual contouring in the four-chamber view using TomTec Image Arena 4...
August 12, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28794314/geographical-discrimination-of-virgin-olive-oils-from-the-tunisian-coasts-by-combining-fatty-acids-and-phenolic-acids-profiles-within-a-multivariate-analysis
#2
Hajer Ben Hlima, Rayda Ben Ayed, Karim Ennouri, Slim Smaoui
Virgin olive oils extracted from three principal Tunisian olive cultivars (Chemlali, Chetoui and Zarrazi) and coming from four different regions (Sfax, Beja, Gabes and Medenine) along the Tunisian costs were analysed. The quality indices as well as fatty acids and phenolic acids content of oil samples were examined using univariate and multivariate statistical analysis. The finding demonstrated that significant differences (p < 0.05) were found in quality indices between the different cultivars and that fatty acid content is the most informative in discriminating olive oils from production sites that are different by geographical and climatic parameters...
August 8, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28789634/screening-of-nucleotide-variations-in-genomic-sequences-encoding-charged-protein-regions-in-the-human-genome
#3
Sabrine Belmabrouk, Najla Kharrat, Rania Abdelhedi, Amine Ben Ayed, Riadh Benmarzoug, Ahmed Rebai
BACKGROUND: Studying genetic variation distribution in proteins containing charged regions, called charge clusters (CCs), is of great interest to unravel their functional role. Charge clusters are 20 to 75 residue segments with high net positive charge, high net negative charge, or high total charge relative to the overall charge composition of the protein. We previously developed a bioinformatics tool (FCCP) to detect charge clusters in proteomes and scanned the human proteome for the occurrence of CCs...
August 8, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28780022/inferring-rooted-species-trees-from-unrooted-gene-trees-using-approximate-bayesian-computation
#4
Ayed R A Alanzi, James H Degnan
Methods for inferring species trees from gene trees motivated by incomplete lineage sorting typically use either rooted gene trees to infer a rooted species tree, or use unrooted gene trees to infer an unrooted species tree, which is then typically rooted using one or more outgroups. Theoretically, however, it has been known since 2011 that it is possible to consistently infer the root of the species tree directly from unrooted gene trees without assuming an outgroup. Here, we use approximate Bayesian computation to infer the root of the species tree from unrooted gene trees assuming the multispecies coalescent model...
August 2, 2017: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/28777321/prevalence-and-genetic-characteristics-of-staphylococcus-aureus-and-staphylococcus-argenteus-isolates-harboring-panton-valentine-leukocidin-enterotoxins-and-tsst-1-genes-from-food-handlers-in-myanmar
#5
Meiji Soe Aung, Thida San, Mya Mya Aye, San Mya, Win Win Maw, Khin Nyein Zan, Wut Hmone Win Htut, Mitsuyo Kawaguchiya, Noriko Urushibara, Nobumichi Kobayashi
Asymptomatic carriers of toxigenic Staphylococcus aureus are potential source of diseases, including food poisoning. Toxigenic potential and genetic traits of colonizing S. aureus were investigated for 563 healthy food handlers in Myanmar. Carriage of S. aureus was found in 110 individuals (19.5%), and a total of 144 S. aureus isolates were recovered from nasal cavities (110 isolates) and hands (34 isolates). Panton-Valentine leucocidin genes (pvl) were detected in 18 isolates (12.5%), among which 11 isolates were classified into coa-VIa, agr type III, and ST1930 (CC96) that had been also detected in pvl-positive clinical isolates in Myanmar...
August 4, 2017: Toxins
https://www.readbyqxmd.com/read/28770589/implications-of-differentiated-care-for-successful-art-scale-up-in-a-concentrated-hiv-epidemic-in-yangon-myanmar
#6
REVIEW
Anita Mesic, Julie Fontaine, Theingy Aye, Jane Greig, Thin Thin Thwe, Laura Moretó-Planas, Jarmila Kliesckova, Khin Khin, Nana Zarkua, Lucia Gonzalez, Erwin Lloyd Guillergan, Daniel P O'Brien
INTRODUCTION: National AIDS Programme in Myanmar has made significant progress in scaling up antiretroviral treatment (ART) services and recognizes the importance of differentiated care for people living with HIV. Indeed, long centred around the hospital and reliant on physicians, the country's HIV response is undergoing a process of successful decentralization with HIV care increasingly being integrated into other health services as part of a systematic effort to expand access to HIV treatment...
July 21, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28769970/genetic-diversity-within-a-global-panel-of-durum-wheat-triticum-durum-landraces-and-modern-germplasm-reveals-the-history-of-alleles-exchange
#7
Hafssa Kabbaj, Amadou T Sall, Ayed Al-Abdallat, Mulatu Geleta, Ahmed Amri, Abdelkarim Filali-Maltouf, Bouchra Belkadi, Rodomiro Ortiz, Filippo M Bassi
Durum wheat is the 10th most important crop in the world, and its use traces back to the origin of agriculture. Unfortunately, in the last century only part of the genetic diversity available for this species has been captured in modern varieties through breeding. Here, the population structure and genetic diversity shared among elites and landraces collected from 32 countries was investigated. A total of 370 entries were genotyped with Axiom 35K array to identify 8,173 segregating single nucleotide polymorphisms (SNPs)...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28760516/-rare-complication-of-renal-transplantation-emphysematous-pyelonephritis
#8
Ahmed Saadi, Haroun Ayed, Omar Karray, Walid Kerkeni, Abderrazak Bouzouita, Mohamed Cherif, Riadh Ben Slama, Amine Derouiche, Mohamed Chebil
Emphysematous pyelonephritis is a necrotizing infection of the renal parenchyma and peri-renal tissues, characterized by the presence of air within the parenchyma of the urinary tract and peri-renal space. This is a severe complication, which involves the functional prognosis of the kidney and the patient's prognosis. The emphysematous pyelonephritis is a rare complication of renal transplantation. Its gravity is linked particularly to the fragility of immunosuppressed patients. The authors report the case of an emphysematous pyelonephritis having occurred 9 months after transplantation in a patient 58 years...
July 28, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/28753977/in-vitro-preservation-of-transgenic-tomato-solanum-lycopersicum-l-plants-overexpressing-the-stress-related-slareb1-transcription-factor
#9
Ayed M Al-Abdallat, Rida A Shibli, Muhanad W Akash, Manar Rabbaa, Tamara Al-Qudah
In vitro preservation of transgenic tomato lines overexpressing the stress-responsive transcription factor SlAREB1 was studied by using slow growth and cryopreservation techniques. Slow growth preservation was performed by using different concentrations of sucrose (0, 100, 200, 300 mm) and abscisic acid (0, 4, 8, 12 μm) in Murashige and Skoog (MS) media, while cryopreservation was conducted by using encapsulation dehydration, V-cryoplates and seeds. Significant differences were observed between tested lines grown on MS media supplemented with 200 mm sucrose where transgenic lines overexpressing SlAREB1 showed improved growth when compared with negative control...
July 21, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28750601/development-and-characterization-of-antibacterial-braided-polyamide-suture-coated-with-chitosan-citric-acid-biopolymer
#10
Faten Debbabi, Sondes Gargoubi, Mohamed Adnene Hadj Ayed, Saber Ben Abdessalem
Braided polyamide sutures are frequently used in dermatologic surgery for wound closure. However, braided sutures promote bacteria proliferation. In order to prevent wound complications due to this effect, antibacterial sutures should be used. The main objective of this study is the development of new non-absorbable antibacterial polyamide braided suture. This paper suggests new coating process that leads to obtain suture uniformly covered by antibacterial film enclosing chitosan, which is known for its antibacterial benefit...
January 1, 2017: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/28749856/evaluation-of-prognostic-factors-and-proposed-changes-to-the-modified-tokuhashi-score-in-patients-with-spinal-metastases-from-breast-cancer
#11
Kimberly-Anne Tan, Jiong Hao Tan, Aye Sandar Zaw, Joel Yong Hao Tan, Hwee Weng Dennis Hey, Naresh Kumar
STUDY DESIGN: A retrospective study of all patients with histologically-confirmed breast cancer spinal metastases presenting to a single instituition between May 2001-April 2012. OBJECTIVES: To investigate if the 2014mT is more accurate than the 2005mT. SUMMARY OF BACKGROUND DATA: The commonly used 2005 modified Tokuhashi score (2005mT) has become more inaccurate as oncologists move towards treating tumours according to their molecular and genomic profile, rather than their tissue-of-origin...
July 26, 2017: Spine
https://www.readbyqxmd.com/read/28747413/barium-aspiration-through-a-tracheo-oesophageal-fistula-caused-by-percutaneous-tracheostomy
#12
Moayad Majed Alqurashi, Majed Ayed Alshammari, Hamdan Al-Jahdali
No abstract text is available yet for this article.
July 26, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28744317/podophyllotoxin-extracted-from-juniperus-sabina-fruit-inhibits-rat-sperm-maturation-and-fertility-by-promoting-epididymal-epithelial-cell-apoptosis
#13
Shuwu Xie, Guoting Li, Lijuan Qu, Ruihua Zhong, Ping Chen, Zhigang Lu, Jieyun Zhou, Xiangjie Guo, Zhao Li, Aying Ma, Yueying Qian, Yan Zhu
This study aimed to investigate the antifertility effect of Juniperus sabina fruit on male rats and its possible mechanism, and hence it might be developed as a potential nonhormonal male contraceptive. Male rats were intragastrically fed for consecutive 8-week and 4-week recovery with the fruit of J. Sabina, and sperm maturation, serum testosterone level, and histopathology were analyzed. Epididymal epithelial cell culture was prepared for detection of podophyllotoxin activities. Furthermore, cell proliferation, transmission electron microscopy, Annexin V/Propidium iodide, TUNEL, RT-PCR, ELISA, and western blotting were examined...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28739447/laparoscopic-resection-of-interaortocaval-paraganglioma-in-left-lateral-decubitus-with-video
#14
H Najah, A Ayed, S Noullet, G Godiris-Petit, F Menegaux, N Jumentier, C Trésallet
No abstract text is available yet for this article.
July 21, 2017: Journal of Visceral Surgery
https://www.readbyqxmd.com/read/28736239/%C3%AE-trcp1-is-a-vacillatory-regulator-of-wnt-signaling
#15
Marcus John Long, Hong-Yu Lin, Saba Parvez, Yi Zhao, Jesse Richard Poganik, Paul Huang, Yimon Aye
Simultaneous hyperactivation of Wnt and antioxidant response (AR) are often observed during oncogenesis. However, it remains unclear how the β-catenin-driven Wnt and the Nrf2-driven AR mutually regulate each other. The situation is compounded because many players in these two pathways are redox sensors, rendering bolus redox signal-dosing methods uninformative. Herein we examine the ramifications of single-protein target-specific AR upregulation in various knockdown lines. Our data document that Nrf2/AR strongly inhibits β-catenin/Wnt...
July 10, 2017: Cell Chemical Biology
https://www.readbyqxmd.com/read/28735300/caveolin-1-expression-as-a-prognostic-marker-in-triple-negative-breast-cancers-of-asian-women
#16
Joe Yeong, Aye Aye Thike, Murasaki Ikeda, Jeffrey Chun Tatt Lim, Bernett Lee, Seigo Nakamura, Jabed Iqbal, Puay Hoon Tan
BACKGROUND: Triple-negative breast cancers (TNBCs) are defined by their lack of oestrogen receptor, progesterone receptor and epidermal growth factor receptor 2. Although heterogeneous, the majority are aggressive and treatment options are limited. Caveolin acts as tumour suppressor or promoter depending on the cancer type. AIM: In this study, we aimed to determine if the expression levels of the candidate biomarker caveolin-1 on stromal or tumour cells were associated with clinicopathological parameters and disease outcomes in TNBCs from an ethnically diverse cohort of Asian women...
July 22, 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28729377/abundant-dystrophic-calcifications-mimicking-aortic-valve-abscess-in-a-patient-undergoing-elective-aortic-valve-replacement
#17
Adam L Booth, Christine Q Li, Ghannam Ayed Al-Dossari, Heather L Stevenson
Dystrophic calcifications of the aortic valve may cause symptomatic aortic stenosis and account for a significant portion of patients who undergo elective valve replacement. Calcifications appearing grossly as a cloudy fluid surrounding the aortic valve leaflets are an uncommon finding. Normally, calcified aortic valves are characterised by large, nodular masses within the aortic cusps. We report a case of dystrophic calcifications on a stenotic aortic valve encountered intraoperatively, which was suggestive of infective endocarditis and abscess formation...
July 19, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28722601/rabies-in-myanmar-prevalent-preventable-but-not-prioritized
#18
Thet Thet Mu, Aye Aye Sein, Chit Soe, Nan Phyu Phyu Aung, Tint Tint Kyi, Josh Hanson
Despite the availability of proven measures to prevent the disease, rabies now kills more people in Myanmar than malaria. Although there are challenges in controlling rabies in such a large and culturally diverse country, Myanmar's successful National Malaria Control Program demonstrates what can be achieved with sufficient political, financial, and scientific commitment. Presently, however, Myanmar lacks a comparable program to coordinate the multifaceted approach that is necessary to control rabies. The national government has invested heavily in improving access to postexposure prophylaxis, but there should also be an emphasis on other, more cost-effective strategies, particularly mass canine vaccination, which has been an essential component of successful rabies elimination programs in other countries...
June 12, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28719025/frequency-risk-factors-and-outcomes-of-central-nervous-system-relapse-in-lymphoma-patients-treated-with-dose-adjusted-epoch-plus-rituximab
#19
M K Malecek, A M Petrich, S Rozell, B Chu, S Trifilio, N Galanina, M Maurer, U Farooq, B Link, G S Nowakowski, C Nabhan, A O Ayed
Background Central nervous system (CNS) relapse in non-Hodgkin lymphoma (NHL) is a rare but serious complication that carries a poor prognosis. The use of infusional etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab (EPOCH-R) for frontline treatment of diffuse large B cell lymphoma (DLBCL) is increasing, though little is known about incidence of and risk factors for CNS relapse with this regimen Patients and methods We completed a chart review of patients with NHL who received EPOCH-R as front line therapy...
July 18, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/28701359/oxldl-induced-endothelial-proliferation-via-rho-rock-akt-p27-kip1-signaling-prevention-by-cholesterol-loading
#20
Chongxu Zhang, Crystal Adamos, Myung-Jin Oh, Jugajyoti Baruah, Manuela A A Ayee, Dolly Mehta, Kishore K Wary, Irena Levitan
Oxidized modifications of LDL (oxLDL) are known to play a major role in endothelial dysfunction and the development of atherosclerosis. In this study, we provide comparative analysis of the effects of two major types of oxLDL, copper oxidized LDL (Cu(2+)-oxLDL) and Lipoxygenase oxidized LDL (LPO-oxLDL) on proliferation of Human Aortic Endothelial Cells (HAECs). We show that Cu(2+)-oxLDL enhances HAECs proliferation in a dose and oxidation-dependent manner. Similarly, LPO-oxLDL also has a positive effect on HAECs proliferation...
July 12, 2017: American Journal of Physiology. Cell Physiology
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