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"Tetralogy of fallot"

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https://www.readbyqxmd.com/read/29027295/progression-of-late-post-operative-atrial-fibrillation-in-patients-with-tetralogy-of-fallot
#1
Tanwier T T K Ramdjan, Elisabeth M J P Mouws, Christophe P Teuwen, Gustaf D S Sitorus, Charlotte A Houck, Ad J J C Bogers, Natasja M S de Groot
INTRODUCTION: ToF patients are at risk for ventricular deterioration at a relatively young age, which can be aggravated by AF development. Therefore, knowledge on AF development and its timespan of progression is essential to guide treatment strategies for AF. OBJECTIVE: We examined late post-operative AF onset and progression in ToF patients during long-term follow-up after ToF correction. In addition, co-existence of regular supraventricular tachyarrhythmias (SVT) and ventricular tachyarrhythmias (VTA) was analyzed...
October 13, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29025761/genome-wide-association-study-to-find-modifiers-for-tetralogy-of-fallot-in-the-22q11-2-deletion-syndrome-identifies-variants-in-the-gpr98-locus-on-5q14-3
#2
Tingwei Guo, Gabriela M Repetto, Donna M McDonald McGinn, Jonathan H Chung, Hiroko Nomaru, Christopher L Campbell, Anna Blonska, Anne S Bassett, Eva W C Chow, Elisabeth E Mlynarski, Ann Swillen, Joris Vermeesch, Koen Devriendt, Doron Gothelf, Miri Carmel, Elena Michaelovsky, Maude Schneider, Stephan Eliez, Stylianos E Antonarakis, Karlene Coleman, Aoy Tomita-Mitchell, Michael E Mitchell, M Cristina Digilio, Bruno Dallapiccola, Bruno Marino, Nicole Philip, Tiffany Busa, Leila Kushan-Wells, Carrie E Bearden, Małgorzata Piotrowicz, Wanda Hawuła, Amy E Roberts, Flora Tassone, Tony J Simon, Esther D A van Duin, Thérèse A van Amelsvoort, Wendy R Kates, Elaine Zackai, H Richard Johnston, David J Cutler, A J Agopian, Elizabeth Goldmuntz, Laura E Mitchell, Tao Wang, Beverly S Emanuel, Bernice E Morrow
BACKGROUND: The 22q11.2 deletion syndrome (22q11.2DS; DiGeorge syndrome/velocardiofacial syndrome) occurs in 1 of 4000 live births, and 60% to 70% of affected individuals have congenital heart disease, ranging from mild to severe. In our cohort of 1472 subjects with 22q11.2DS, a total of 62% (n=906) have congenital heart disease and 36% (n=326) of these have tetralogy of Fallot (TOF), comprising the largest subset of severe congenital heart disease in the cohort. METHODS AND RESULTS: To identify common genetic variants associated with TOF in individuals with 22q11...
October 2017: Circulation. Cardiovascular Genetics
https://www.readbyqxmd.com/read/29019299/additional-mechanism-for-left-ventricular-dysfunction-chronic-pulmonary-regurgitation-decreases-left-ventricular-preload-in-patients-with-tetralogy-of-fallot
#3
Pekka Ylitalo, Eero Jokinen, Kirsi Lauerma, Miia Holmström, Olli M Pitkänen-Argillander
BACKGROUND: Right ventricular dysfunction in patients with tetralogy of Fallot and significant pulmonary regurgitation may lead to systolic dysfunction of the left ventricle due to altered ventricular interaction. We were interested in determining whether chronic pulmonary regurgitation affects the preload of the left ventricle. In addition, we wanted to study whether severe chronic pulmonary regurgitation would alter the preload of the left ventricle when compared with patients having preserved pulmonary valve annulus...
October 11, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/29017776/early-outcomes-of-percutaneous-pulmonary-valve-implantation-using-the-edwards-sapien-xt-transcatheter-heart-valve-system
#4
Nikolaus A Haas, Ronald Giacomo Carere, Oliver Kretschmar, Eric Horlick, Josep Rodés-Cabau, Daniël de Wolf, Marc Gewillig, Michael Mullen, Anja Lehner, Cornelia Deutsch, Peter Bramlage, Peter Ewert
BACKGROUND: Patients with congenital or acquired heart defects affecting the pulmonary valve and right ventricular outflow tract (RVOT) commonly require multiple surgical interventions, resulting in significant morbidity. A less invasive alternative is percutaneous pulmonary valve implantation (PPVI). Though studies have previously reported the safety and efficacy of the early generation transcatheter heart valves (THVs), data on more recent devices are severely lacking. METHODS AND RESULTS: We performed a multinational, multicentre, retrospective, observational registry analysis of patients who underwent PPVI using the Edwards SAPIEN XT THV...
October 6, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29016767/dual-loop-circuit-of-ventricular-tachycardia-in-repaired-tetralogy-of-fallot-patient
#5
Masateru Takigawa, Ruairidh Martin, Takeshi Kitamura, Stefano Capellino Be, Pierre Jaïs, Frederic Sacher
No abstract text is available yet for this article.
August 8, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28993061/risk-comparison-for-prenatal-use-of-analgesics-and-selected-birth-defects-national-birth-defects-prevention-study-1997-2011
#6
Julia D Interrante, Elizabeth C Ailes, Jennifer N Lind, Marlene Anderka, Marcia L Feldkamp, Martha M Werler, Lockwood G Taylor, James Trinidad, Suzanne M Gilboa, Cheryl S Broussard
PURPOSE: To compare the use of nonsteroidal anti-inflammatory drugs (NSAIDs) and/or opioids to the use of acetaminophen without NSAIDs or opioids with respect to associations with birth defects. METHODS: We used data from the National Birth Defects Prevention Study (1997-2011). Exposure was self-reported maternal analgesic use from the month before through the third month of pregnancy (periconceptional). Adjusted odds ratios (aORs) were calculated to examine associations with 16 birth defects...
September 20, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/28992910/extreme-tetralogy-of-fallot-with-polycythemia-in-a-ferret-mustela-putorius-furo
#7
Sara Dias, Marta Planellas, Albert Canturri, Jaume Martorell
A 5-month-old, intact male ferret (Mustela putorius furo) was presented with apathy, tachypnea and exercise intolerance. On initial physical examination, tachypnea and cyanosis were the two primary clinical signs detected. The complete blood count also revealed a severe polycythemia, with lymphopenia, neutrophilia and eosinophilia. Further diagnostic imaging tests were performed. The thoracic radiographs revealed cardiomegaly and a diffuse alveolar pulmonary pattern. Consequently, an echocardiography was performed and showed an interventricular septal defect, pulmonic artery occlusion, overriding of the aorta and right ventricle hypertrophy...
June 2017: Topics in Companion Animal Medicine
https://www.readbyqxmd.com/read/28991257/contribution-of-rare-inherited-and-de-novo-variants-in-2-871-congenital-heart-disease-probands
#8
Sheng Chih Jin, Jason Homsy, Samir Zaidi, Qiongshi Lu, Sarah Morton, Steven R DePalma, Xue Zeng, Hongjian Qi, Weni Chang, Michael C Sierant, Wei-Chien Hung, Shozeb Haider, Junhui Zhang, James Knight, Robert D Bjornson, Christopher Castaldi, Irina R Tikhonoa, Kaya Bilguvar, Shrikant M Mane, Stephan J Sanders, Seema Mital, Mark W Russell, J William Gaynor, John Deanfield, Alessandro Giardini, George A Porter, Deepak Srivastava, Cecelia W Lo, Yufeng Shen, W Scott Watkins, Mark Yandell, H Joseph Yost, Martin Tristani-Firouzi, Jane W Newburger, Amy E Roberts, Richard Kim, Hongyu Zhao, Jonathan R Kaltman, Elizabeth Goldmuntz, Wendy K Chung, Jonathan G Seidman, Bruce D Gelb, Christine E Seidman, Richard P Lifton, Martina Brueckner
Congenital heart disease (CHD) is the leading cause of mortality from birth defects. Here, exome sequencing of a single cohort of 2,871 CHD probands, including 2,645 parent-offspring trios, implicated rare inherited mutations in 1.8%, including a recessive founder mutation in GDF1 accounting for ∼5% of severe CHD in Ashkenazim, recessive genotypes in MYH6 accounting for ∼11% of Shone complex, and dominant FLT4 mutations accounting for 2.3% of Tetralogy of Fallot. De novo mutations (DNMs) accounted for 8% of cases, including ∼3% of isolated CHD patients and ∼28% with both neurodevelopmental and extra-cardiac congenital anomalies...
October 9, 2017: Nature Genetics
https://www.readbyqxmd.com/read/28988308/improving-the-role-of-echocardiography-in-studying-the-right-ventricle-of-repaired-tetralogy-of-fallot-patients-comparison-with-cardiac-magnetic-resonance
#9
Carolina D'Anna, Armando Caputi, Benedetta Natali, Benedetta Leonardi, Aurelio Secinaro, Gabriele Rinelli, Alessia Del Pasqua, Claudia Esposito, Adriano Carotti, Fabrizio Drago, Marcello Chinali
Right ventricular (RV) evaluation represents one of the major clinical tasks in the follow-up of repaired tetralogy of Fallot patients (rToF) with pulmonary valve regurgitation, as both severe RV dilatation and dysfunction are key factors in defining the need of pulmonary valve replacement. The aim of our study was to report the diagnostic accuracy of echocardiography in the identification of rToF patients with severely dilated and/or depressed RV as compared to cardiac magnetic resonance (CMR). Among our patients with rToF, a subgroup of 95 (17...
October 7, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28975024/quantification-of-pulmonary-regurgitation-in-patients-with-repaired-tetralogy-of-fallot-by-2d-phase-contrast-mri-differences-between-the-standard-method-of-velocity-averaging-and-a-pixel-wise-analysis
#10
Julio Sotelo, Pablo Bächler, Jesús Urbina, Gerard Crelier, Lida Toro, Myriam Ferreiro, Israel Valverde, Marcelo Andia, Cristian Tejos, Pablo Irarrazaval, Sergio Uribe
OBJECTIVES: To compare the values of pulmonary regurgitation in patients with repaired Tetralogy of Fallot quantified from two-dimensional phase-contrast data, by using a new pixel-wise analysis and the standard velocity-averaging method. DESIGN: Quantitative in silico and in vivo analysis. SETTING: Hospital Sótero del Río. The magnetic resonance images were acquired using a Philips Achieva 1.5T scanner. PARTICIPANTS: Twenty-five patients with repaired Tetralogy of Fallot who underwent cardiovascular magnetic resonance imaging requested by their referring physicians were included in this study...
January 2017: JRSM Cardiovascular Disease
https://www.readbyqxmd.com/read/28974283/is-mesocardia-with-left-sided-caval-vein-draining-to-coronary-sinus-a-contraindication-for-a-percutaneous-pulmonary-valve-implantation-a-case-description
#11
Marinos Kantzis, Christoph M Happel, Nikolaus A Haas
Introduction Although the right jugular vein approach for percutaneous pulmonary valve implantation is well described, there are no reports that describe a percutaneous pulmonary valve implantation through a left superior caval vein to coronary sinus pathway. Case A 14-year-old female with tetralogy of Fallot, mesocardia, left superior caval vein draining into the coronary sinus, and hemiazygos continuation of the inferior caval vein underwent ventricular septal defect closure, with homograft insertion from the right ventricle to the pulmonary artery, patch augmentation of the left pulmonary artery, and creation of an atrial communication...
October 4, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28970652/the-need-for-extracorporeal-membrane-oxygenation-in-adults-undergoing-congenital-heart-surgery-impact-and-trends-of-utilization
#12
Salvatore Aiello, Rohit S Loomba, Connor Kriz, Matthew Buelow, Saurabh Aggarwal, Rohit R Arora
INTRODUCTION: Adults with congenital heart disease (ACHD) represent a population with unique health-care needs. Many patients require cardiac surgery, with some requiring postoperative extracorporeal membrane oxygenation (ECMO). This study aimed to identify the risk factors for the need of postoperative ECMO and characterize the impact of ECMO on admission characteristics. METHODS: Data from the 2005-2012 iterations of the Nationwide Inpatient Sample were used. ACHD admissions over 18 years with a documented cardiac surgery were included...
September 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28970037/a-novel-method-for-evaluating-regional-rv-function-in-the-adult-congenital-heart-with-low-dose-ct-and-squeez-processing
#13
Francisco J Contijoch, Daniel W Groves, Zhennong Chen, Marcus Y Chen, Elliot R McVeigh
BACKGROUND: Measuring local RV function in adult congenital heart disease (ACHD) with echocardiography or MRI is challenging because of the complex geometry and existing pacing devices. Visual assessment of ventricular function via low-dose cardiac CT has been recently performed. This pilot study assessed whether low-dose 4D cine CT combined with automatic measurement of regional shortening could quantify right-ventricular function in ACHD patients. METHODS: Seven patients with Tetralogy of Fallot either contraindicated for MRI or assessed for coronary artery disease and seven non-congenital patients were imaged with ECG-gated cardiac CT utilizing a 320-detector row scanner...
September 29, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28965732/physical-fitness-and-metabolic-syndrome-in-children-with-repaired-congenital-heart-disease-compared-with-healthy-children
#14
Mahmoud Zaqout, Kristof Vandekerckhove, Nathalie Michels, Thierry Bove, Katrien François, Daniel De Wolf
OBJECTIVE: To determine whether children who underwent surgery for congenital heart disease (CHD) are as fit as their peers. STUDY DESIGN: We studied 66 children (6-14 years) who underwent surgery for ventricular septal defect (n = 19), coarctation of aorta (n = 10), tetralogy of Fallot (n = 15), and transposition of great arteries (n = 22); and 520 healthy children (6-12 years). All children performed physical fitness tests: cardiorespiratory fitness, muscular strength, balance, flexibility, and speed...
September 28, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28957534/combining-computer-modelling-and-cardiac-imaging-to-understand-right-ventricular-pump-function
#15
John Walmsley, Wouter van Everdingen, Maarten J Cramer, Frits W Prinzen, Tammo Delhaas, Joost Lumens
Right ventricular (RV) dysfunction is a strong predictor of outcome in heart failure and is a key determinant of exercise capacity. Despite these crucial findings, the RV remains understudied in the clinical, experimental, and computer modelling literature. This review outlines how recent advances in using computer modelling and cardiac imaging synergistically help to understand RV function in health and disease. We begin by highlighting the complexity of interactions that make modelling the RV both challenging and necessary, and then summarize the multiscale modelling approaches used to date to simulate RV pump function in the context of these interactions...
October 1, 2017: Cardiovascular Research
https://www.readbyqxmd.com/read/28933244/ventricular-fibrillation-and-myocardial-depression-following-pulmonary-valve-replacement-in-tetralogy-of-fallot-with-an-intramural-coronary-artery-and-coronary-artery-compression-by-chest-tube
#16
Mubbasheer Ahmed, Nathan E Thompson, Susan R Foerster, Michele A Frommelt, Michael E Mitchell, John P Scott
We describe the case of a 10-year-old male with a history of repaired Tetralogy of Fallot and known intramural right coronary artery (RCA) who presented for bioprosthetic pulmonary valve replacement. The operation was complicated by postoperative ventricular fibrillation arrest. Selective coronary angiography revealed external compression of the mid-RCA by a mediastinal chest tube that improved immediately upon removal of the tube. Ultimately, the patient required additional unroofing of the intramural coronary for full recovery...
January 1, 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28932358/estimating-pressure-gradients-by-auscultation-how-technology-echocardiography-can-help-improve-clinical-skills
#17
Rohini L Kadle, Colin K L Phoon
AIM: To extend our previously-published experience in estimating pressure gradients (PG) via physical examination in a large patient cohort. METHODS: From January 1, 1997 through December 31, 2009, an attending pediatric cardiologist compared clinical examination (EXAM) with Doppler-echo (ECHO), in 1193 patients with pulmonic stenosis (PS, including tetralogy of Fallot), aortic stenosis (AS), and ventricular septal defect (VSD). EXAM PG estimates were based primarily on a murmur's pitch, grade, and length...
August 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28928619/percutaneous-management-of-complex-acquired-aortic-coarctation-in-an-adult-with-tetralogy-of-fallot-and-pulmonary-atresia
#18
Michael D Seckeler, Emily Lawson, Brent J Barber, Scott E Klewer
We present the case of a female adult with complex cyanotic congenital heart disease who had long-standing thoracic aortic obstruction due to scarring from earlier surgical procedures. She was symptomatic but felt to be too high risk for surgical intervention. With careful planning, she was able to undergo successful stenting of her aorta with subsequent clinical improvement. This case highlights some of the complexities of caring for adults with congenital heart disease and the importance of a thorough understanding of their anatomy and physiology and prior interventions before undertaking interventions...
September 2017: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/28928615/stenting-of-right-ventricular-outflow-tract-in-tetralogy-of-fallot-with-subarterial-ventricular-septal-defect-a-word-of-caution
#19
Jonathan Lee, Sivakumar Sivalingam, Mazeni Alwi
We report a case of Tetralogy of Fallot with severe cyanosis who underwent a successful right ventricular outflow tract stenting. Follow-up echocardiography revealed moderate aortic regurgitation due to the impingement of the stent on the aortic valve. The patient underwent successful surgical correction at which time the stent was removed completely with a resolution of the aortic regurgitation.
September 2017: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/28928608/intraocular-pressure-in-children-after-congenital-heart-surgery-a-single-center-study
#20
Sunali Goyal, Paul H Phillips, Lamonda A Corder, Michael J Robertson, Xiomara Garcia, Michael L Schmitz, Punkaj Gupta
BACKGROUND: The impact of varied cardiac physiologies on intraocular pressure (IOP) among children undergoing heart operations is unknown. AIM: The aim of this study was to determine the IOP among children with varying cardiovascular physiologies and varying hemodynamics after their heart operation. SETTING AND DESIGN: This was a prospective, observational study. MATERIALS AND METHODS: Patients ≤18 years undergoing congenital heart surgery were included in this study...
September 2017: Annals of Pediatric Cardiology
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