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https://www.readbyqxmd.com/read/28805473/the-impact-of-persistence-with-mirabegron-usage-versus-switching-to-onabotulinumtoxina-on-healthcare-costs-and-resource-utilization-in-patients-with-overactive-bladder-in-the-united-states
#1
Daniel Bin Ng, Robert Espinosa, Scott J Johnson, David Walker, Katherine Gooch
Aims To compare healthcare costs and resource utilization in patients with overactive bladder (OAB) in the United States who switch from mirabegron to onabotulinumtoxinA (onabotA) with those who persist on mirabegron. Materials and methods A retrospective observational claims analysis of the OptumHealth Administrative Claims database conducted between April 1, 2012 and September 30, 2015 used medical and pharmacy claims to identify patients with at least one OAB diagnosis who switched from mirabegron to onabotA (onabotA group) or persisted on mirabegron for at least 180 days (mirabegron persisters)...
August 14, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28799925/investigation-of-phosphate-removal-from-aqueous-solution-by-both-coal-gangues
#2
Wei Ding, Shuqin Bai, Haorong Mu, Gaowa Naren
Equilibrium studies were carried out for the adsorption of phosphate onto newly discharged coal gangue and spontaneous combustion coal gangue, which are industrial solid residues. The experimental data were fitted to the two-parameter equations of Freundlich, Langmuir, Temkin, and Dubinin-Radushkevich and the three-parameter equations of the Redlich-Peterson, Sips and Toth isotherms by non-linear method. All three-parameter isotherm equations have a higher correlation coefficient than the two-parameter isotherm equations...
August 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28799892/the-impact-of-socio-cultural-factors-on-transmission-of-taenia-spp-and-echinococcus-granulosus-in-kosovo
#3
M Alishani, K Sherifi, A Rexhepi, A Hamidi, M T Armua-Fernandez, F Grimm, D Hegglin, P Deplazes
Echinococcus granulosus sensu latu (s.l.) and Taenia hydatigena are common parasites of ruminant intermediate hosts in the Balkans. Transmission is linked mainly to home slaughtering and the feeding of infected organs to dogs. In Kosovo, many old sheep are slaughtered particularly during Eid al-Adha (Feast of Sacrifice). To determine whether this tradition could affect parasite transmission, we compared the probability of 504 dogs to contract taenid infections after deworming during one period before Eid al-Adha and a similar period beginning with this event...
August 11, 2017: Parasitology
https://www.readbyqxmd.com/read/28798771/diagnosis-of-oral-hairy-leukoplakia-the-importance-of-ebv-in-situ-hybridization
#4
Luana L Martins, José Henrique F Rosseto, Natália Silva Andrade, Juliana Bertoldi Franco, Paulo Henrique Braz-Silva, Karem L Ortega
Oral hairy leukoplakia (OHL) is caused by the Epstein-Barr virus (EBV), which has been related to HIV infection. In situ hybridization (ISH) is the gold-standard diagnosis of OHL, but some authors believe in the possibility of performing the diagnosis based on clinical basis. The aim of this study is diagnose incipient lesions of OHL by EBV ISH of HIV-infected patients and the possible correlations with clinical characteristics of the patients. Ninety-four patients were examined and those presenting with clinical lesions compatible to OHL were submitted to biopsy prior to EBV ISH...
2017: International Journal of Dentistry
https://www.readbyqxmd.com/read/28797871/factors-affecting-knee-laxity-following-anterior-cruciate-ligament-reconstruction-using-a-hamstring-tendon
#5
Shinya Yanagisawa, Masashi Kimura, Keiichi Hagiwara, Atsuko Ogoshi, Tomoyuki Nakagawa, Hiroyuki Shiozawa, Takashi Ohsawa
BACKGROUND: The aim of the present study was to investigate the correlation between the pre-operative and intraoperative factors that predict postoperative knee laxity following anterior cruciate ligament (ACL) reconstruction using a hamstring tendon. METHODS: The subjects included 108 patients (male, n=49; female, n=59) with ACL-deficient knees who had undergone double-bundle reconstruction. The median time between injury and surgery (TBIS) was 27.5weeks (range one to 504)...
August 7, 2017: Knee
https://www.readbyqxmd.com/read/28797180/book-review-occupational-therapy-with-aging-adults-promoting-quality-of-life-through-collaborative-practice-barney-karen-perkinson-margaret-eds-2016-occupational-therapy-with-aging-adults-promoting-quality-of-life-through-collaborative-practice-st-louis-mo
#6
https://www.readbyqxmd.com/read/28797048/objective-quantification-of-the-food-proximity-effect-on-grapes-chocolate-and-cracker-consumption-in-a-swedish-high-school-a-temporal-analysis
#7
Billy Langlet, Petter Fagerberg, Andrew Glossner, Ioannis Ioakimidis
Close food proximity leads to increased short-term energy intake, potentially contributing to the long-term development of obesity. However, its precise effects on eating behaviour are still unclear, especially with food available for extended periods of time. This study involved two similar high school student groups (15-17 years old), which had ad libitum access to grapes, chocolates and crackers during an hour-long experimental session. In the distal condition the foods were placed 6 meters away from the students (n = 24), in contrast to the proximal condition (n = 17) were the food was placed near the students...
2017: PloS One
https://www.readbyqxmd.com/read/28796301/reproductive-health-and-bodily-integrity-in-tanzania
#8
Judith Westeneng, Ben D'Exelle
Several policy initiatives support the empowerment of women to improve their reproductive health. Little is known, however, about the inverse effect that reproductive health might have on women's empowerment. Women are pressured to conform to their reproductive role, and an inability to do so might affect their empowerment, including control over their own body. Using a panel dataset of 504 married women in Northern Tanzania, we find that women who experienced a pregnancy loss show more tolerant views of partner violence and that child mortality lowers their perceived control over the sexual relationship with their spouse...
August 10, 2017: Studies in Family Planning
https://www.readbyqxmd.com/read/28793070/the-lawsuits-to-antineoplastic-drugs-the-tip-of-an-iceberg
#9
Thaís Jeronimo Vidal, Elaine Lazzaroni Moraes, Maely Peçanha Favero Retto, Mario Jorge Sobreira da Silva
The lawsuits with antineoplastic drugs generate high costs for governments and require careful analysis to ensure efficient and adequate health results. This study analyzed cases conducted by federal entities to a reference institute for the treatment of cancer for technical opinion. Data were collected from copies of the cases examined from July 1 to December 31, 2013. It was analyzed: therapeutic subgroups, presence in essential drug list, drug registry, off-label use, indications of clinical practice guidelines, drug incorporation in Brazilian Health System and estimated value of court cases...
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28781210/suction-drains-in-esthetic-breast-implant-exchange-are-associated-with-surgical-site-infections-a-retrospective-cohort-study
#10
Eran Hadad, Itay Wiser, Adaya Rosenthal, Geva Landau, Ella Ziv, Lior Heller
BACKGROUND AND OBJECTIVE: Surgical site infection (SSI) following esthetic breast implant exchange occurs in up to 2% of procedures. The effect of suction drains on SSI risk in these cases remains controversial. This study aimed to assess the SSI risk in the presence of suction drains after esthetic exchange of breast implants. METHODS: This is a retrospective cohort study of patients undergoing esthetic breast implant exchange between 2012 and 2015. SSI was determined according to the definition of the Center for Disease Control and Prevention...
July 6, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28780836/-retrospectively-analysis-on-95-postpartum-hemorrhage-women-treated-with-obstetrics-and-gynecology-in-intensive-care-unit
#11
A J Pan, T J Yang, Q Mei, L Zhang, L Chen, D B Wu, B Liu
Objective: To review the clinical aspects and pathogenesis of postpartum hemorrhage (PPH) and investigate the optimal protocols for intervention. Methods: From February 2009 to December 2015, data of normal labour and casearean birth women admitted to intensive care unit (ICU) in our hospital because of hematobilia were selected. 95 patients were divided into three groups (e. g ≥500-1 000 ml, ≥1 000-1 500 ml, ≥1 500-2 500 ml and ≥2 500 ml group) according to the bleeding volume. A retrospective analysis was performed to study the pathogenesis of PPH, organ function, surgical intervention and clinical prognosis on hemorrhage...
August 1, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28780667/the-association-of-lifetime-physical-inactivity-with-head-and-neck-cancer-a-hospital-based-case-control-analysis
#12
Alexis J Platek, Rikki A Cannioto, John Lewis Etter, Jae Kim, Janine M Joseph, Nicholas R Gulati, Kristina L Schmitt, Emily Callahan, Edgar Khachatryan, Ryan Nagy, Albina Minlikeeva, J Brian Szender, Anurag K Singh, Iris Danziger, Kirsten B Moysich
Despite mounting epidemiological evidence suggesting an inverse association between recreational physical activity and cancer risk, evidence associated with head and neck cancer is scant. We conducted a case-control analysis to examine the associations of lifetime physical inactivity with the risk of head and neck squamous cell carcinoma (HNSCC). We utilized data from the Patient Epidemiology Data System at Roswell Park Cancer Institute (RPCI). Participants included 246 patients with HNSCC and 504 cancer-free controls who received medical services at RPCI between 1990 and 1998...
August 5, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28780110/improving-genetic-evaluation-using-a-multitrait-single-step-genomic-model-for-ability-to-resume-cycling-after-calving-measured-by-activity-tags-in-holstein-cows
#13
Ahmed Ismael, Peter Løvendahl, Anders Fogh, Mogens Sandø Lund, Guosheng Su
The objective of this study was to evaluate the improvement of the accuracy of estimated breeding values for ability to recycle after calving by using information of genomic markers and phenotypic information of correlated traits. The traits in this study were the interval from calving to first insemination (CFI), based on artificial insemination data, and the interval from calving to first high activity (CFHA), recorded from activity tags, which could better measure ability to recycle after caving. The phenotypic data set included 1,472,313 records from 820,218 cows for CFI, and 36,504 records from 25,733 cows for CFHA...
August 2, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28779855/progress-of-unaids-90-90-90-targets-in-a-district-in-kwazulu-natal-south-africa-with-high-hiv-burden-in-the-hipss-study-a-household-based-complex-multilevel-community-survey
#14
Anneke Grobler, Cherie Cawood, David Khanyile, Adrian Puren, Ayesha B M Kharsany
BACKGROUND: With the goal of eliminating new HIV infections, UNAIDS set the ambitious 90-90-90 targets to be achieved by 2020. We assessed whether these targets are being met among participants of the HIV Incidence Provincial Surveillance System (HIPSS) in a high-burden district of South Africa. METHODS: We used data from a HIPSS household-based, cross-sectional survey of HIV prevalence and incidence done in the uMgungundlovu district, KwaZulu-Natal, in 2014 and 2015...
August 2, 2017: Lancet HIV
https://www.readbyqxmd.com/read/28777860/-unexpected-discovery-of-a-fetus-with-dmd-gene-deletion-using-single-nucleotide-polymorphism-array
#15
Shaobin Lin, Yu Zhou, Bingyi Zhou, Heng Gu
OBJECTIVE: To investigate the value of single nucleotide polymorphism array (SNP array) for the identification of de novo mutations in the DMD gene among fetuses. METHODS: G-banded karyotyping and SNP array were performed on a fetus with intrauterine growth restriction but without family history of Duchenne/Becker muscular dystrophy (DMD/BMD). Multiplex ligation-dependent probe amplification (MLPA) was subsequently applied on amniocytes and maternal peripheral blood sample to detect DMD gene deletion/duplication mutations...
August 10, 2017: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
https://www.readbyqxmd.com/read/28777468/technical-note-a-novel-quality-assurance-test-to-identify-gantry-angle-inaccuracies-in-respiratory-gated-vmat-treatments
#16
Emily Hubley, Michael Briscoe, Nicolas Ploquin, Greg Pierce
PURPOSE: During respiratory-gated volumetric modulated arc therapy (VMAT), the radiation beam is turned off each time the target exits the gating window. At the same time, the gantry slows, stops, and rewinds before the beam is turned back on. A quality assurance (QA) test was developed to detect inaccuracies in the gantry angle position between beam-off and beam-on events during respiratory-gated VMAT. METHODS: Strips of Gafchromic(™) EBT3 film were taped to the surface of a Capthan(®) 504 phantom mounted at isocentre...
August 4, 2017: Medical Physics
https://www.readbyqxmd.com/read/28776996/molecular-dynamics-simulations-on-gas-phase-proteins-with-mobile-protons-inclusion-of-all-atom-charge-solvation
#17
Lars Konermann
Molecular dynamics (MD) simulations have become a key tool for examining the properties of electrosprayed protein ions. Traditional force fields employ static charges on titratable sites, whereas in reality, protons are highly mobile in gas-phase proteins. Earlier studies tackled this problem by adjusting charge patterns during MD runs. Within those algorithms, proton redistribution was subject to energy minimization, taking into account electrostatic and proton affinity contributions. However, those earlier approaches described (de)protonated moieties as point charges, neglecting charge solvation, which is highly prevalent in the gas phase...
August 16, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28775101/cardiovascular-risk-after-hospitalisation-for-unexplained-syncope-and-orthostatic-hypotension
#18
Ekrem Yasa, Fabrizio Ricci, Martin Magnusson, Richard Sutton, Sabina Gallina, Raffaele De Caterina, Olle Melander, Artur Fedorowski
OBJECTIVE: To investigate the relationship of hospital admissions due to unexplained syncope and orthostatic hypotension (OH) with subsequent cardiovascular events and mortality. METHODS: We analysed a population-based prospective cohort of 30 528 middle-aged individuals (age 58±8 years; males, 40%). Adjusted Cox regression models were applied to assess the impact of unexplained syncope/OH hospitalisations on cardiovascular events and mortality, excluding subjects with prevalent cardiovascular disease...
August 3, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28774978/draft-genome-sequence-of-cronobacter-sakazakii-gp1999-sequence-type-145-an-epiphytic-isolate-obtained-from-the-tomato-s-rhizoplane-rhizosphere-continuum
#19
Hannah R Chase, Leo Eberl, Roger Stephan, HyeJin Jeong, Chaeyoon Lee, Samantha Finkelstein, Flavia Negrete, Jayanthi Gangiredla, Isha Patel, Ben D Tall, Gopal R Gopinath, Angelika Lehner
We present here the draft genome of Cronobacter sakazakii GP1999, a sequence type 145 strain isolated from the rhizosphere of tomato plants. Assembly and annotation of the genome resulted in a genome of 4,504,670 bp in size, with 4,148 coding sequences, and a GC content of 56.8%.
August 3, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28774644/preincision-initiation-of-dexmedetomidine-maximally-reduces-the-risk-of-junctional-ectopic-tachycardia-in-children-undergoing-ventricular-septal-defect-repairs
#20
Nischal K Gautam, Yuliya Turiy, Chandra Srinivasan
OBJECTIVE: To evaluate whether initiation of dexmedetomidine (DEX) infusion before surgical incision and cardiopulmonary bypass (CPB) versus initiation after CPB had an impact on the incidence of junctional ectopic tachycardia (JET). DESIGN: Retrospective cohort study. SETTING: Single tertiary-care cardiac center. PARTICIPANTS: Children undergoing cardiopulmonary bypass for repair of congenital heart disease involving ventricular septal defects between January 2010 and February 2013...
April 10, 2017: Journal of Cardiothoracic and Vascular Anesthesia
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