keyword
MENU ▼
Read by QxMD icon Read
search

504

keyword
https://www.readbyqxmd.com/read/28731591/a-sedation-protocol-with-fasting-and-shorter-sleep-leads-to-mri-success
#1
Takahisa Kimiya, Shinichiro Sekiguchi, Tatsuhiko Yagihashi, Mie Arai, Hirotaka Takahashi, Takao Takahashi
BACKGROUND: Young children undergoing magnetic resonance imaging (MRI) require sedation. In June 2013, Tokyo Metropolitan Ohtsuka Hospital (TMOH) introduced an oral sedation protocol for young children undergoing MRI; the protocol included instructions on fasting before sedation, and recommended a shorter duration of sleep the night before MRI. We compared the MRI success rate before and after the introduction of this protocol. METHODS: The eligible subjects were children under 3 years old who underwent MRI by appointment at TMOH between October 2012 and March 2014, under sedation with triclofos sodium...
July 21, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28729470/detection-and-monitoring-of-lung-inflammation-in-cystic-fibrosis-during-respiratory-tract-exacerbation-using-diffusion-weighted-magnetic-resonance-imaging
#2
Pierluigi Ciet, Silvia Bertolo, Mirco Ros, Eleni Rosalina Andrinopoulou, Valentina Tavano, Francesca Lucca, Thorsten Feiweier, Gabriel P Krestin, Harm A W M Tiddens, Giovanni Morana
The aim was to investigate whether diffusion-weighted magnetic resonance imaging (DWI) detects and monitors inflammatory and lung function changes during respiratory tract exacerbations (RTE) treatment in patients with cystic fibrosis (CF).29 patients with RTE underwent DWI pre- and post-antibiotic treatment. A control group of 27 stable patients, matched for age and sex, underwent DWI with the same time gap as those undergoing RTE treatment. Clinical status and lung function were assessed at each DWI time point...
July 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28728181/the-value-of-diagnostic-work-up-in-the-evaluation-of-white-dot-syndromes
#3
Neal V Palejwala, Gagan Sawhney, Matthew Raecker, Chrstina J Flaxel, Steven Yeh
BACKGROUND AND OBJECTIVE: To determine the diagnostic yield of systemic work-up in white dot syndromes. PATIENTS AND METHODS: A retrospective chart review. RESULTS: Eighty-six consecutive patients with a diagnosis of a white dot syndrome were identified. Forty-three had a diagnosis of birdshot chorioretinopathy. Overall, 395 diagnostic tests were performed with a diagnostic yield of 11.9%. The test with the greatest diagnostic yield was HLA-A29 typing (89%)...
July 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28724494/pharmacokinetics-of-a-novel-transdermal-fentanyl-solution-in-rhesus-macaques-macaca-mulatta
#4
Gregory W Salyards, Marie-Josee Lemoy, Heather K Knych, Ashley E Hill, Kari L Christe
Rhesus macaques (Macaca mulatta) are the most commonly used NHP biomedical model and experience both research and clinical procedures requiring analgesia. Opioids are a mainstay of analgesic therapy. A novel, transdermal fentanyl solution (TFS) has been developed as a long-acting, single-administration topical opioid and was reported to provide at least 4 d of effective plasma concentrations in beagles (Canis familiaris). To evaluate the pharmacokinetic profile of TFS in healthy adult rhesus macaques, we used a 2-period, 2-treatment crossover study of a single topical administration of 1...
July 1, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28718168/higher-reoperation-rate-following-cervical-disc-replacement-in-a-retrospective-long-term-comparative-study-of-715-patients
#5
Martin Skeppholm, Thomas Henriques, Tycho Tullberg
PURPOSE: To evaluate rates of secondary surgical interventions in a cohort treated with fusion (ACDF), artificial disc replacement (ADR) or a posterior surgical procedure (PP) because of a cervical degenerative pathology. METHODS: 715 patients treated with any primary cervical surgical intervention between the years 2000 and 2010 were retrospectively evaluated regarding frequency of secondary surgery between the years 2000 and 2015, thus giving a follow-up time of minimum 5 years...
July 17, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28715287/outcome-measures-correlated-with-falls-in-nursing-home-residents-a-pilot-study
#6
Heidi S Moyer, Jeffrey Gale, Stephen Severe, Heather J Braden, Scott Hasson
Most fall risk and normal values are collected from the community-dwelling population, which is not representative of nursing home residents. The purpose of this study was twofold: 1) to determine the relationship of clinical impairment and activity limitation variables to the number of falls in nursing home residents; and 2) to determine the amount of variability that can be explained for the number of falls from these predictor variables. Seventeen active nursing home residents (83.7 ± 11.7 years) consented to participate...
July 17, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28714793/equivalent-knee-injury-and-osteoarthritis-outcome-scores-12-and-24-months-after-anterior-cruciate-ligament-reconstruction-results-from-the-swedish-national-knee-ligament-register
#7
Kristian Samuelsson, Robert A Magnussen, Eduard Alentorn-Geli, Ferid Krupic, Kurt P Spindler, Christer Johansson, Magnus Forssblad, Jón Karlsson
BACKGROUND: It is not clear whether Knee injury and Osteoarthritis Outcome Score (KOOS) results will be different 1 or 2 years after anterior cruciate ligament (ACL) reconstruction. PURPOSE: To investigate within individual patients enrolled in the Swedish National Knee Ligament Register whether there is equivalence between KOOS at 1 and 2 years after primary ACL reconstruction. STUDY DESIGN: Cohort study; Level of evidence, 2. METHODS: This cohort study was based on data from the Swedish National Knee Ligament Register during the period January 1, 2005, through December 31, 2013...
July 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28710909/evaluation-of-the-interaction-between-genetic-variants-of-gad1-and-mirna-in-bipolar-disorders
#8
Yu-Chu Ella Chung, Shao-Chien Chen, Li-Chung Chuang, Wei-Liang Shih, Yi-Hang Chiu, Mong-Liang Lu, Hsi-Chung Chen, Po-Hsiu Kuo
BACKGROUND: Glutamic acid dehydrogenase 1 (GAD1) serves as the rate-limiting enzyme for synthesizing GABA, and is reported to be associated with several psychiatric disorders. The present study examined the effects of GAD1 genetic variants on bipolar disorder (BD) and its subtypes. Moreover, we investigated functional interactions between genetic variants and miRNAs via algorithm prediction and experimental validation. METHODS: A case-control study was conducted with 280 BD patients and 200 healthy controls...
July 10, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28708919/retrospective-evaluation-of-the-influence-of-the-collar-surface-topography-on-peri-implant-bone-preservation
#9
Jose Alfredo Mendonça, Plinio Mendes Senna, Carlos Eduardo Francischone, Carlos Eduardo Francischone Junior, Neuza Maria de Souza Picorelli Assis, Bruno Salles Sotto-Maior
PURPOSE: To evaluate the influence of the collar surface topography on peri-implant marginal bone preservation. MATERIALS AND METHODS: A total of 156 patients who received at least one cylindrical implant of regular diameter with an external-hexagon platform in the posterior region of the maxilla or mandible were recalled to the office for a retrospective evaluation. Implantation sites and implant length information were recorded, and implants were divided according to the collar surface topography: machined (M) or rough (R) surface...
July 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28704818/active-surveillance-cultures-and-targeted-decolonization-are-associated-with-reduced-methicillin-susceptible-staphylococcus-aureus-infections-in-vlbw-infants
#10
Lukas Wisgrill, Johanna Zizka, Lukas Unterasinger, Judith Rittenschober-Böhm, Thomas Waldhör, Athanasios Makristathis, Angelika Berger
BACKGROUND: Methicillin-susceptible Staphylococcus aureus (MSSA) is a major contributor to infectious episodes of very low birth weight infants (VLBWI), resulting in significant morbidity and mortality. OBJECTIVE: To examine the efficacy and safety of surveillance cultures and the decolonization of MSSA-colonized VLBWI. METHODS: VLBWI admitted to our neonatal wards in 2011-2016 were retrospectively analyzed. Rates of MSSA-attributable infections were compared before and after the implementation of active surveillance cultures and the decolonization of MSSA-colonized patients...
July 14, 2017: Neonatology
https://www.readbyqxmd.com/read/28702176/monitoring-and-evaluating-the-adherence-to-a-complementary-food-supplement-ying-yang-bao-among-young-children-in-rural-qinghai-china-a-mixed-methods-evaluation-study
#11
Qiong Wu, Yanfeng Zhang, Suying Chang, Wei Wang, Michelle Helena van Velthoven, Huijun Han, Min Xing, Li Chen, Xiaozhen Du, Robert W Scherpbier
BACKGROUND: Large investments are currently made in community-based complementary food supplement (Ying Yang Bao, YYB) programs to improve nutrition of young children in rural areas in China. However, there is a lack of knowledge about the experience and challenges of implementing YYB programs in China. We aimed to: 1) monitor distribution of YYB; 2) assess children's adherence to and acceptability of YYB; and 3) evaluate community-based strategies to improve the program. METHODS: This mixed methods evaluation study combined data from surveys and focus groups that took place during a controlled interventional evaluation trial...
June 2017: Journal of Global Health
https://www.readbyqxmd.com/read/28698656/gene-gene-and-gene-environment-interactions-influence-platinum-based-chemotherapy-response-and-toxicity-in-non-small-cell-lung-cancer-patients
#12
Jia-Jia Cui, Lei-Yun Wang, Tao Zhu, Wei-Jing Gong, Hong-Hao Zhou, Zhao-Qian Liu, Ji-Ye Yin
Platinum-based chemotherapy is a major therapeutic regimen of lung cancer. Various single nucleotide polymorphisms (SNPs) reported were associated with platinum-based chemotherapy response and drug toxicity. However, neither of the studies explored this association from SNP-SNP interaction perspective nor taking into effects of SNP-environment consideration simultaneously. We genotyped 504 polymorphisms and explore the association of gene-gene and gene-environment interactions with platinum-based chemotherapy response and toxicity in 490 NSCLC patients...
July 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28693501/knowledge-and-practice-of-immediate-newborn-care-among-health-care-providers-in-eastern-zone-public-health-facilities-tigray-ethiopia-2016
#13
Abadi Kidanemariam Berhe, Fitiwi Tinsae, Gebremedhin Gebreegziabher
BACKGROUND: According to WHO (2013) report the number of under five-year mortality in Ethiopia was 195,504, out of this 84,437 was from neonatal death and this mortality is related to immediate obstetric and newborn care of babies provided by health care providers; But little was known about the level of knowledge and practice related to immediate newborn care and their associated factors among health care providers generally in Tigray region and specifically in the Eastern Zone so the aim of this study was to assess knowledge and practice of immediate newborn care and associated factors among health care providers in the Eastern zone public health facilities, Tigray, Ethiopia...
July 11, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28692690/risk-of-surgical-site-infection-acute-kidney-injury-and-clostridium-difficile-infection-following-antibiotic-prophylaxis-with-vancomycin-plus-a-beta-lactam-versus-either-drug-alone-a-national-propensity-score-adjusted-retrospective-cohort-study
#14
MULTICENTER STUDY
Westyn Branch-Elliman, John E Ripollone, William J O'Brien, Kamal M F Itani, Marin L Schweizer, Eli Perencevich, Judith Strymish, Kalpana Gupta
BACKGROUND: The optimal regimen for perioperative antimicrobial prophylaxis is controversial. Use of combination prophylaxis with a beta-lactam plus vancomycin is increasing; however, the relative risks and benefits associated with this strategy are unknown. Thus, we sought to compare postoperative outcomes following administration of 2 antimicrobials versus a single agent for the prevention of surgical site infections (SSIs). Potential harms associated with combination regimens, including acute kidney injury (AKI) and Clostridium difficile infection (CDI), were also considered...
July 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28692117/clinical-significance-and-expression-of-puma-mcl-1-and-p53-in-human-renal-cell-carcinoma-and-para-carcinoma-tissues
#15
H B Xia, H W Cui, L Su, Z H Zhang, X Y Yang, S Q Ning, X L Su
We investigated the expression level of p53 upregulated modulator of apoptosis (PUMA), myeloid cell leukemia-I (MCL-1), and p53 in renal cell carcinoma (RCC) and para-carcinoma tissues, as well as their clinical significance. The expression levels of PUMA, MCL-1, and p53 in RCC and para-carcinoma tissues were measured using immunohistochemical and quantitative real-time PCR methods. Correlations between protein expression and pathological characteristics were analyzed. Renal clear cell carcinoma showed elevated MCL-1 and p53 protein expression (P > 0...
July 6, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28691778/a-different-way-to-study-frequency-volume-charts-in-patients-with-nocturia
#16
Marie-Astrid Denys, An-Sofie Goessaert, Brecht Dejaeghere, Veerle Decalf, Piet Hoebeke, Karel Everaert
BACKGROUND: Nocturia results from a mismatch between bladder capacity and nocturnal urine production (NUP), which is determined with a frequency volume charts (FVC). AIM: This is the first study that aimed to describe variations in nocturia severity and its associated factors by evaluating FVCs per single 24 h-period. METHODS: This was a post-hoc analysis of patients who completed a 72 h-FVC in prospective, observational studies. The nocturnal polyuria index (NPi ) was defined as the ratio of nocturnal and 24 h urine output...
July 10, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28691172/physical-education-increases-daily-moderate-to-vigorous-physical-activity-and-reduces-sedentary-time
#17
Kerli Mooses, Maret Pihu, Eva-Maria Riso, Aave Hannus, Priit Kaasik, Merike Kull
BACKGROUND: Physical activity (PA) is important to mental and physical health. Physical education (PE) lessons have the potential to increase daily moderate to vigorous PA (MVPA) and reduce sedentary time (SED). We measured MVPA and SED in primary school PE, determined the contribution of PE to daily MVPA and SED, and compared PA on days with and without PE. METHODS: PA was measured in 504 first (ages 7-9) and second (ages 10-12) school level children for 1 school week, with inclusion criteria of at least 10 hours of valid data...
August 2017: Journal of School Health
https://www.readbyqxmd.com/read/28690228/-socio-psychological-factors-relevant-to-suicidal-ideation-among-patients-with-aids-in-changsha
#18
Huiying Wang, Min Wang, Furong Jiang, Zhisheng Liu, Honghong Wang, Jianling Li
To explore the rates of suicide ideation and the relevant factors among patients with HIV/AIDS (PLWHA) in Changsha for obtaining scientific evidence to reduce suicidal ideation rates among PLWHA.
 Methods: A total of 504 PLWHA were surveyed in an AIDS hospital in Changsha, by using Self-Made Socio-Demographic Scale, Self-rating Depression Scale, Self-rating Anxiety Scale, and Beck Scale for Suicide Ideation-Chinese Version.
 Results: There were 13.9%, 26.6% and 27.2% of PLWHA suffered suicidal ideation in the last week, at the most depressive moments and all their lives, respectively...
June 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28689364/oncologists-influence-on-receipt-of-adjuvant-chemotherapy-does-it-matter-whom-you-see-for-treatment-of-curable-breast-cancer
#19
Steven J Katz, Sarah T Hawley, Irina Bondarenko, Reshma Jagsi, Kevin C Ward, Timothy P Hofer, Allison W Kurian
PURPOSE: We know little about whether it matters which oncologist a breast cancer patient sees with regard to receipt of chemotherapy. We examined oncologists' influence on use of recurrence score (RS) testing and chemotherapy in the community. METHODS: We identified 7810 women with stages 0-II breast cancer treated in 2013-15 through the SEER registries of Georgia and Los Angeles County. Surveys were sent 2 months post-surgery, (70% response rate, n = 5080)...
July 8, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28687722/a-meta-analysis-on-progressive-atrophy-in-intractable-temporal-lobe-epilepsy-time-is-brain
#20
REVIEW
Lorenzo Caciagli, Andrea Bernasconi, Samuel Wiebe, Matthias J Koepp, Neda Bernasconi, Boris C Bernhardt
OBJECTIVE: It remains unclear whether drug-resistant temporal lobe epilepsy (TLE) is associated with cumulative brain damage, with no expert consensus and no quantitative syntheses of the available evidence. METHODS: We conducted a systematic review and meta-analysis of MRI studies on progressive atrophy, searching PubMed and Ovid MEDLINE databases for cross-sectional and longitudinal quantitative MRI studies on drug-resistant TLE. RESULTS: We screened 2,976 records and assessed eligibility of 248 full-text articles...
July 7, 2017: Neurology
keyword
keyword
10156
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"