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amiotrophic lateral sclerosis treatment

A B Usakli, S Gurkan, F Aloise, G Vecchiato, F Babiloni
An efficient alternative channel for communication without overt speech and hand movements is important to increase the quality of life for patients suffering from Amiotrophic Lateral Sclerosis or other illnesses that prevent correct limb and facial muscular responses. Often, such diseases leave the ocular movements preserved for a relatively long time. The aim of this study is to present a new approach for the hybrid system which is based on the recognition of electrooculogram (EOG) and electroencephalogram (EEG) measurements for efficient communication and control...
2009: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Daniela Catarzi, Vittoria Colotta, Flavia Varano
Glutamic acid (Glu) is the major excitatory neurotransmitter in the mammalian central nervous system (CNS) where it is involved in the physiological regulation of different processes. It has been well established that excessive endogenous Glu is associated with many acute and chronic neurodegenerative disorders such as cerebral ischaemia, epilepsy, amiotrophic lateral sclerosis, Parkinson's, and Alzheimer's disease. These data have consequently added great impetus to the research in this field. In fact, many Glu receptor antagonists acting at the N-methyl-D-aspartic acid (NMDA), 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid (AMPA), and/or kainic acid (KA) receptors have been developed as research tools and potential therapeutic agents...
March 2007: Medicinal Research Reviews
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