keyword
https://read.qxmd.com/read/38214088/l4-5-disc-herniation-not-unusually-accompanied-with-l5-s1-low-grade-spondylolytic-spondylolisthesis
#21
JOURNAL ARTICLE
Haicheng Zhou, Qingshuang Zhou, Bin Wang, Yong Qiu, Zezhang Zhu, Zhen Liu, Xu Sun
OBJECTIVE: Isthmic spondylolisthesis (IS) is distinguished by a congenital defect or acquired fracture of the pars interarticularis. Numerous studies on L5 low-grade IS have been carried out; however, there is a paucity of data regarding the condition of L5 IS concomitant with L4/5 disc herniation. This study aimed to identify the incidence rate and to illustrate the possible risk factors for L4/5 disc herniation in L5 low-grade IS patients. METHODS: A total of 268 consecutive patients diagnosed as L5/S1 low-grade IS between May 2017 and May 2022 were retrospectively enrolled in this study...
January 12, 2024: Orthopaedic Surgery
https://read.qxmd.com/read/38213336/the-effect-of-interbody-cage-parameters-on-the-rate-of-subsidence-in-single-level-anterior-cervical-discectomy-and-fusion-acdf-a-retrospective-analysis-of-98-patients
#22
JOURNAL ARTICLE
Aleeza Safdar, Benjamin Headley, Marcus Rommelman, Ahmad Haseeb, Rouzbeh Motiei-Langroudi
INTRODUCTION: Subsidence is a relatively common consequence after anterior cervical discectomy and fusion (ACDF) surgery. This study aimed to identify the effect of radiological and non-radiological risk factors on subsidence after a single-level ACDF surgery with cage and plate. METHODS: This is a retrospective cohort study of patients who underwent ACDF for radiculopathy or myelopathy at an academic center, University of Kentucky Albert Chandler Hospital, Lexington, Kentucky, United States, between January 2010 and January 2020...
December 2023: Curēus
https://read.qxmd.com/read/38181514/optimizing-the-entry-point-for-medullary-hip-screws
#23
JOURNAL ARTICLE
Kevin Huang, Zachary A Rockov, Lukas O Foster, Jawad Najdawi, Abrianna S Robles, Geoffrey S Marecek
INTRODUCTION: Medullary hip screws (MHSs) are the most common treatment of intertrochanteric hip fractures because they can be used for varied fracture patterns and resist shortening. Identifying the appropriate MHS entry point can be intellectually and technically challenging. We aimed to quantify the variability in the ideal entry point (IEP) for MHSs. METHODS: Standing alignment radiographs of 50 patients were evaluated using TraumaCad (Brainlab). The femoral neck shaft angle and the offset from the tip of the greater trochanter (GT) to the femur's longitudinal axis ('greater trochanter offset') were measured...
March 15, 2024: Journal of the American Academy of Orthopaedic Surgeons
https://read.qxmd.com/read/38176061/polyelectrolyte-brushes-with-protein-like-nanocolloids
#24
JOURNAL ARTICLE
Tatiana O Popova, Oleg V Borisov, Ekaterina B Zhulina
Electrostatic interaction of ampholytic nanocolloidal particles (NPs), which mimic globular proteins, with polyelectrolyte brushes is analyzed within mean-field Poisson-Boltzmann approximation. In accordance with experimental findings, the theory predicts that an electrostatic driving force for the particle uptake by the brush may emerge when the net charge of the particle in the buffer and the charge of the brush are of the same sign. The origin of this driving force is change in the ionization state of weak cationic and anionic groups on the NP surface provoked by interaction with the brush...
January 4, 2024: Langmuir: the ACS Journal of Surfaces and Colloids
https://read.qxmd.com/read/38165974/coping-self-efficacy-and-social-support-as-predictors-of-adolescent-sex-trafficking-exit-results-of-a-secondary-analysis
#25
JOURNAL ARTICLE
Mary K Twis, Andrea Cimino, Marilyn Plunk
INTRODUCTION: Social work case management services are increasingly available to youth who want to exit commercial sexual exploitation (CSE). However, few empirical studies investigate the efficacy of such services, particularly whether these services promote an exit from CSE. Guided by ecological systems theory and the Intentions to Exit Prostitution (IEP) model, this study investigates the efficacy of social work case management services for youth CSE survivors. METHODS: Youth survivors of CSE (n = 95) participated in a one-group, quasi-experimental double pre/posttest design study...
2024: PloS One
https://read.qxmd.com/read/38152045/mir-22-3p-facilitates-bone-marrow-mesenchymal-stem-cell-osteogenesis-and-fracture-healing-through-the-sostdc1-pi3k-akt-pathway
#26
JOURNAL ARTICLE
Chunqiu Wang, Xinguo Wang, Hui Cheng, Jiahu Fang
Bone fractures are the most common form of musculoskeletal trauma worldwide. Numerous microRNAs (miRNAs) have been suggested to be participants in regulating bone-related diseases. Recent studies revealed the regulatory role of miR-22-3p in osteogenic differentiation, but its role in fracture healing has not been investigated previously. Here, a rat femoral fracture model was established, Bone marrow mesenchymal stem cells (BMSCs) were isolated to detect the specific function and underlying mechanisms of miR-22-3p...
December 28, 2023: International Journal of Experimental Pathology
https://read.qxmd.com/read/38132536/interaction-of-polyanionic-and-polycationic-brushes-with-globular-proteins-and-protein-like-nanocolloids
#27
REVIEW
Tatiana O Popova, Ekaterina B Zhulina, Oleg V Borisov
A large number of experimental studies have demonstrated that globular proteins can be absorbed from the solution by both polycationic and polyanionic brushes when the net charge of protein globules is of the same or of the opposite sign with respect to that of brush-forming polyelectrolyte chains. Here, we overview the results of experimental studies on interactions between globular proteins and polycationic or polyanionic brushes, and present a self-consistent field theoretical model that allows us to account for the asymmetry of interactions of protein-like nanocolloid particles comprising weak (pH-sensitive) cationic and anionic groups with a positively or negatively charged polyelectrolyte brush...
December 9, 2023: Biomimetics
https://read.qxmd.com/read/38131712/correlations-between-educational-struggle-toxic-sites-by-school-district-and-demographic-variables-with-geographical-information-system-projections
#28
JOURNAL ARTICLE
Junu Shrestha, Raihan K Khan, Shane McClintock, John DeGroote, Catherine L Zeman
This correlational study associated data on children enrolled in individualized educational plans in their K-12 schools (IEP) and an algorithm-calculated score of neurotoxins at contaminated sites located in each school district. The study also mapped and projected the correlations using Geographical Information System (GIS) technology. These data were populated in ArcMap 10.5 (a GIS software) for generating maps and data to conduct geospatial analysis. A total of 1 Superfund site and 39 CERCLA sites were identified as contaminated sites for this analysis...
December 9, 2023: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/38117679/developmental-delay-and-behavior-challenges-in-an-internationally-adopted-child
#29
JOURNAL ARTICLE
Lianna R Lipton, Lisa Prock, Stephen Camarata, Jason Fogler, Sarah S Nyp
Jay is a 6-year-old boy who was referred to a multidisciplinary developmental clinic for evaluation because of speech/language delays and challenging behaviors. He attends kindergarten with an Individualized Education Program (IEP) supporting developmental challenges with speech/language, motor, and academic skills.Jay was reportedly born full-term after an uneventful pregnancy and lived with his biological family for several months before transitioning to institutional care. Shortly before his first birthday, he transitioned to the first of 3 foster homes...
December 20, 2023: Journal of Developmental and Behavioral Pediatrics: JDBP
https://read.qxmd.com/read/38113137/special-education-assessment-practices-that-support-eligibility-and-intervention
#30
JOURNAL ARTICLE
Lissa A Power-deFur
PURPOSE: Federal special education requirements specify that information districts must gather and review during the process of finding a student eligible for special education and developing a student's Individualized Education Program (IEP). The purpose of this tutorial is to describe the federal requirements related to evaluation and assessment and to apply best practices in assessment to those expectations, thereby enhancing teams' ability to identify students' strengths and needs, determine eligibility for services, and create high-quality IEPs...
December 19, 2023: Language, Speech, and Hearing Services in Schools
https://read.qxmd.com/read/38076747/the-basics-of-cbm-what-bcbas-need-to-know
#31
JOURNAL ARTICLE
Kate LaLonde, Rena VanDerwall, Meagan Walsh
Curriculum-based measurement (CBM) is an approach to measuring student academic growth and evaluating the effectiveness of instruction (Deno, Exceptional Children , 52 , 219-232, 1985) that was developed, in part, based on characteristics of applied behavior analysis. Learning to administer and use CBM data is commonly part of teacher preparation programs, but less common in behavior analysis graduate programs (Schreck et al. Behavioral Interventions , 31 , 355-376, 2016; Schreck & Mazur, Behavioral Interventions , 23 , 201-212, 2008)...
December 2023: Behavior Analysis in Practice
https://read.qxmd.com/read/38062984/increased-accumulation-of-the-advanced-glycation-endproduct-ne-carboxymethyl-lysine-in-the-intramyocardial-vasculature-in-patients-with-epicarditis
#32
JOURNAL ARTICLE
U Baylan, A Baidoshvili, S Simsek, C G Schalkwijk, Hwm Niessen, Paj Krijnen
Advanced glycation end-products (AGEs) are implicated in the pathogenesis of vascular disease. In previous studies we have found increased deposition of N(e)-(carboxymethyl)lysine (CML) in intramyocardial vasculature in the heart in acute myocardial infarction and myocarditis. It is known that the process of inflammation plays a role in the formation of AGEs. In this study we have explored the presence of CML (a major AGE) in the heart of patients with epicarditis using a monoclonal anti-CML antibody. Nine patients with epicarditis (n = 9) died and their hearts were used for this study, control were hearts from patients who died from conditions unrelated to heart disease and without signs of myocarditis or epicarditis CML deposition and complement were significantly increased in patients with epicarditis compared to control hearts...
December 8, 2023: International Journal of Experimental Pathology
https://read.qxmd.com/read/38054576/circular-rna-circvapa-modulates-macrophage-pyroptosis-in-sepsis-induced-acute-lung-injury-through-targeting-mir-212-3p-sirt1-nrf2-nlrp3-axis
#33
JOURNAL ARTICLE
Yanjing Huang, Jinquan Lin, Zhiwei Wu, Yiming Li
Sepsis-induced acute lung injury (ALI) is an inflammatory condition involving the pyroptosis of macrophages. This study investigated the role of circular RNA hsa_circ_0006990 (circVAPA) in regulating macrophage pyroptosis in ALI and the underlying mechanisms. The expression pattern of circVAPA was examined in the mouse model of ALI and in the LPS-treated RAW264.7 macrophage cell line. Lung tissue damage was evaluated by haematoxylin and eosin staining, immunohistochemistry and a myeloperoxidase activity assay...
December 6, 2023: International Journal of Experimental Pathology
https://read.qxmd.com/read/38046353/alumina-hydroxyapatite-millimetric-spheres-for-cadmium-ii-removal-in-aqueous-medium
#34
JOURNAL ARTICLE
Pamela Nair Silva-Holguín, Nahum A Medellín-Castillo, E Armando Zaragoza-Contreras, Simón Yobanny Reyes-López
Heavy metals can act as selective agents in the development and proliferation of antibiotic-resistant bacteria through a process called coselection. In the year 2050, an estimated 10 million deaths will be caused by antibiotic-resistant bacteria; therefore, the presence of heavy metals in bodies of water represents an environmental and sanitary threat that requires efficient treatment processes and/or materials for their removal. In the present study, the effect of the hydroxyapatite coating on the adsorbent capacity of cadmium in alumina spheres was evaluated...
November 28, 2023: ACS Omega
https://read.qxmd.com/read/38042049/a-flexible-capacity-metric-creatinine-sensor-based-on-polygon-shape-polyvinylpyrrolidone-cuo-and-fe-2-o-3-nrds-electrodeposited-on-three-dimensional-tio-2-v-2-o-5-polypyrrole-nanocomposite
#35
JOURNAL ARTICLE
H Dehghan-Manshadi, M Mazloum-Ardakani, S A Mozaffari
The innovations of the present work include these items; (i) Design and preparation of three-dimensional flexible conductive polymeric nanocomposites (3D-FCPNCs) containing polypyrrole (PPy), V2 O5 and TiO2 and modification of their surface with polygon-shape polyvinylpyrrolidone/CuO nanorods (PVP/CuO NRDs) and Fe2 O3 NRDs using an hierarchical process based on isoelectric point (IEP), (ii) Application of the prepared surfaces as the flexible enzymeless creatinine sensors using four calibration curves (impedimetric, real capacitance (C'), imaginary capacitance (C″) and double layer capacitance (Cdl )) obtained from electrochemical impedance spectroscopy (EIS) technique...
November 27, 2023: Biosensors & Bioelectronics
https://read.qxmd.com/read/38039981/using-a-social-model-to-guide-individualized-education-program-development-and-change-educational-paradigms-to-be-critically-inclusive
#36
JOURNAL ARTICLE
Kimberly A Murza, P Charlie Buckley
PURPOSE: The Individuals with Disabilities Education Act explicitly acknowledges disability as a natural part of the human experience. However, special education services, including speech-language services, often focus on remediating the characteristics of the individual with the disability rather than addressing the disabling conditions of the school environment or leveraging the supports and resources available or potentially available to the student. The purpose of this article is to provide a social model of disability framework to guide Individualized Education Program (IEP) development and change educational paradigms around language and communication...
December 1, 2023: Language, Speech, and Hearing Services in Schools
https://read.qxmd.com/read/38035542/a-balancing-act-how-school-based-speech-language-pathologists-navigate-their-efforts-related-to-individual-education-plans-and-multi-tiered-systems-of-support
#37
JOURNAL ARTICLE
Lesley Sylvan, Harmony Kingsley, Grace Bartolett, Madeleine Gouck
PURPOSE: Speech-language pathologists (SLPs) in public schools have a key role in assessment, intervention, program design, compliance, and prevention. They address the needs of students of all ages and disorders, ensure the educational relevance of their services, and provide culturally competent care. Given the scope of their work, SLPs must balance and prioritize their varying responsibilities in school settings. This study investigates how SLPs navigate their involvement with the prevention-oriented framework Multi-Tiered System of Supports (MTSS) while providing direct support to students with disabilities through Individualized Education Programs (IEPs)...
November 30, 2023: Language, Speech, and Hearing Services in Schools
https://read.qxmd.com/read/38002906/indices-of-narrative-language-associated-with-disability
#38
JOURNAL ARTICLE
Norah M Almubark, Gabriela Silva-Maceda, Matthew E Foster, Trina D Spencer
Narratives skills are associated with long-term academic and social benefits. While students with disabilities often struggle to produce complete and complex narratives, it remains unclear which aspects of narrative language are most indicative of disability. In this study, we examined the association between a variety of narrative contents and form indices and disability. Methodology involved drawing 50 K-3 students with Individual Education Programs (IEP) and reported language concerns from a large diverse sample ( n = 1074)...
November 15, 2023: Children
https://read.qxmd.com/read/37992409/workload-versus-caseload-an-exploratory-comparison-study-of-individualized-education-program-progress-and-other-outcomes
#39
JOURNAL ARTICLE
Charles H Carlin
PURPOSE: The purpose of this study was to obtain preliminary data about the effectiveness of four workload approaches (WAs) that were implemented in public school settings. The WAs were compared to each other and the caseload approach (CA). METHOD: Five speech-language pathologists were selected to implement one of the four WAs, and two used the CA. Data were collected in the areas of Individualized Education Program (IEP) progress, classroom performance, delivery of services, workload parameters, and stakeholder perceptions...
November 22, 2023: Language, Speech, and Hearing Services in Schools
https://read.qxmd.com/read/37991201/anti-inflammatory-and-healing-effect-of-the-polysaccharidic-extract-of-opuntia-ficus-indica-cladodes-in-cutaneous-excisional-wounds-in-rats
#40
JOURNAL ARTICLE
Beatriz Lima Adjafre, Iásly Costa Lima, Ana Paula Negreiros Nunes Alves, Rafael Aires Lessa, Arcelina Pacheco Cunha, Maria Gonçalves Pereira, Ana Maria Sampaio Assreuy, Mário Rogério Lima Mota
This study aimed to investigate the anti-inflammatory and wound healing effects of the polysaccharide extract from Opuntia ficus-indica cladodes (TPL-Ofi) using a rat cutaneous wound model. After anaesthesia, four 7-mm-diameter dorsal wounds per animal (n = 6/group for each experimental day of evaluation) were created in female Wistar rats using a surgical punch. The animals were treated topically twice daily with TPL-Ofi (0.01-1%; treated group) or sterile saline (control group) for a period of 21 days...
November 22, 2023: International Journal of Experimental Pathology
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